==================================================
Coprecipitation between Pip5k1b and Dvls irt Wnt3a
==================================================

  *** Pip5k1b[Ab] copptby[WB] xDvl3[tAb] is increased irt Wnt3a (30 min)
    *** cells: HEK293T<xDvl3> in BMS
    *** source: 18772438-Fig-3j

=====================================================
Coprecipitation between Pip5k1b and Pi4k2a irt Wnt3a
=====================================================

  *** Pip5k1b[Ab] copptby[WB] xPi4k2a[tAb] is increased irt Wnt3a (30 min)
    *** cells: HEK293T<xPi4k2a> in BMS
    *** source: 19561074-Fig-5c

====================================
Direct Activation of Pip5k1b by Dvls
====================================

  *** rPip5k1b IVLKA(PI4P)[TLC] is increased by rDvl3
    *** cells: none
    *** source: 18772438-Fig-3k
  *** rPip5k1b IVLKA(PtdIns)[TLC] is increased by rDvl1(1-200)"Dix"
    *** cells: none
    *** inhibited by: rDvl1(376-503)"Dep" [substitution]
    *** inhibited by: rDvl1(201-375)"Pdz" [substitution]
    *** source: 19561074-Fig-4d

===================
Direct Interactions
===================

Pip5k1b/Dvl1--

  *** rPip5k1b[His] boundby[WB] rDvl1[GST] is detectable
    *** cells: none
    *** source: 18772438-Fig-S6f

Pi4k2a/Pip5k1b--

  *** rPip5k1b[tAb] boundby[WB] rPi4k2a[GST] is detectable
    *** cells: none
    *** source: 19561074-Fig-S2b

===============
Coprecipitation
===============

Pip5k1b/Dvl1--

  *** xPip5k1b[tAb] copptby[WB] xDvl1[tAb] is detectable
    *** cells: HEK293T<xPip5k1a><xDvl1> in BMS
    *** unaffected by: xDvl1(1-200)"N" [substitution]
    *** partially inhibited by: xDvl1(201-375)"P" [substitution]
    *** inhibited by: xDvl1(376-503)"D" [substitution]
    *** inhibited by: xDvl1(504-695)"C" [substitution]
    *** source: 18772438-Fig-S6e
  *** xPip5k1b[tAb] copptby[WB] xDvl1[tAb] is detectable
    *** cells: HEK293T<xPip5k1a><xDvl1> in BMS
    *** unaffected by: xPip5k1b(1-319)"N1" [substitution]
    *** unaffected by: xPip5k1b(20-410)"K1" [substitution]
    *** inhibited by: xPip5k1b(223-540)"C1" [substitution]
    *** unaffected by: xPip5k1b(1-270)"N2" [substitution]
    *** inhibited by: xPip5k1b(271-540)"C2" [substitution]
    *** source: 18772438-Fig-S6d
  *** xPip5k1b[tAb] copptby[WB] xDvl1[tAb] is detectable
    *** cells: HEK293T<xPip5k1b><xDvl1> in BMS
    *** source: 18772438-Fig-S6c
  *** xPip5k1b[tAb] copptby[WB] xDvl1[tAb] is detectable
    *** cells: HEK293T<xDvl1><xPip5k1b> in BMS
    *** unaffected by: xPi4k2a [addition]
    *** source: 19561074-Fig-5a

Pip5k1b/Pi4k2a--

  *** xPip5k1b[tAb] copptby[WB] xPi4k2a[tAb] is detectable
    *** cells: HEK293T<xPip5k1b><xPi4k2a> in BMS
    *** source: 19561074-Fig-S2a

