=============
Transcription
=============

Hmgb1-- and/or Hmgb2-- and/or Hmgb3--  ???

  *** Ifnb1-gene mRNA[RTPCR] is increased irt CpGa-transfection (times)
    *** cells: mFLpDCs in BMS
    *** times: 0 6++ 12+ hr
    *** partially reqs: Hmgb1 [KO]
    *** source: 19890330-Fig-3b
  *** Ifnb1-gene mRNA[RTPCR] is increased irt CpGa-transfection (times)
    *** cells: RAW2647 in BMS
    *** times: 0 3+ 6++ hr
    *** partially reqs: Hmgb1 and/or Hmgb2 and/or Hmgb3 [KO]
    *** source: 19890330-Fig-S5b

no extras

  *** Ifnb1-gene mRNA[RTPCR] is increased irt CpG-2006 (times)
    *** cells: hPDCs in BMS
    *** times: 0 3+ 15 hr
    *** source: 12707322-Fig-1c
  *** Ifnb1-gene mRNA[RTPCR] is increased irt CpG-2216 (times)
    *** cells: hPDCs in BMS
    *** times: 0 3+ 15++ hr
    *** source: 12707322-Fig-1c

contradictions

  *** Ifnb1-gene mRNA[RTPCR] is unchanged irt CpGa (times)
    *** cells: RAW2647 in BMS
    *** times: 0 3 6 hr
    *** source: 19890330-Fig-S5b

=========
Secretion
=========

  *** Ifnb1[Ab] secretion[ELISA] is increased irt CpG-2006 (48 hr)
    *** cells: hPDCs in BMS
    *** partially inhibited by: anti-Clec4c [pretreatment]
    *** source: 12707322-Fig-8b
  *** Ifnb1[Ab] secretion[ELISA] is increased irt CpG-2006 (48 hr)
    *** cells: hPDCs in BMS
    *** source: 12707322-Fig-1a
  *** Ifnb1[Ab] secretion[ELISA] is increased irt CpG-2006 (48 hr)
    *** cells: hPDCs in BMS
    *** unaffected by: anti-IfnaR [cotreatment]
    *** source: 12707322-Fig-4c
  *** Ifnb1[Ab] secretion[ELISA] is increased irt CpG-2216 (48 hr)
    *** cells: hPDCs in BMS
    *** partially inhibited by: anti-Clec4c [pretreatment]
    *** source: 12707322-Fig-8b
  *** Ifnb1[Ab] secretion[ELISA] is increased irt CpG-2216 (48 hr)
    *** cells: hPDCs in BMS
    *** partially inhibited by: anti-IfnaR [cotreatment]
    *** source: 12707322-Fig-4c
  *** Ifnb1[Ab] secretion[ELISA] is increased irt CpG-2216 (48 hr)
    *** cells: hPDCs in BMS
    *** source: 12707322-Fig-1a
  *** Ifnb1[Ab] secretion[ELISA] is unchanged irt CpG-2006 (48 hr)
    *** cells: hPDCs in BMS
    *** unaffected by: Cd40L [cotreatment]
    *** source: 12707322-Fig-11b


