  *** xMek1(S218D/S222D)"CA"[tAb]IP phos(S298)[phosAb] is detectable
    *** cells: COS1 in BMLS
    *** unaffected by: xMek1(T292A) [substitution]
    *** inhibited by: xMek1(T292D) [substitution]
    *** source: 14993270-Fig-4a
  *** xMek1(S218D/S222D)"CA"[tAb]IP phos(S298)[phosAb] is detectable
    *** cells: COS1 in BMLS
    *** unaffected by: xMek1(T386A) [substitution]
    *** unaffected by: xMek1(T386D) [substitution]
    *** source: 14993270-Fig-6b
  *** xMek1(S218D/S222D)"CA"[tAb]IP phos(T292)[phosAb] is detectable
    *** cells: COS1 in BMLS
    *** unaffected by: xMek1(T386A) [substitution]
    *** unaffected by: xMek1(T386D) [substitution]
    *** source: 14993270-Fig-6b

  *** xMek1[tAb]IP phos(S298)[phosAb] is detectable
    *** cells: COS1 in BMLS
    *** enhanced by: xMek1(T292A) [substitution]
    *** inhibited by: xMek1(T292D) [substitution]
    *** source: 14993270-Fig-2b
  *** xMek1[tAb]IP phos(S298)[phosAb] is detectable
    *** cells: COS1 in BMLS
    *** inhibited by: xMek1(R291A) [substitution]
    *** enhanced by: xMek1(R291K) [substitution]
    *** source: 14993270-Fig-6a
  *** xMek1[tAb]IP phos(S298)[phosAb] is detectable
    *** cells: COS1 in BMLS "in suspension"
    *** inhibited by: xMek1(T292D) [substitution]
    *** source: 14993270-Fig-5b
  *** xMek1[tAb]IP phos(S298)[phosAb] is detectable
    *** cells: COS1 in BMS
    *** enhanced by: xMek1(T292A) [substitution]
    *** inhibited by: xMek1(T292D) [substitution]
    *** source: 14993270-Fig-2b
  *** xMek1[tAb]IP phos(S298)[phosAb] is detectable
    *** cells: rEFs in BMLS
    *** unaffected by: xMek1(K97A)"KD" [substitution]
    *** inhibited by: xMek1(S298A) [substitution]
    *** source: 17314031-Fig-2b

  *** xMek1[tAb]IP phos(T292)[phosAb] is detectable
    *** cells: COS1 in BMLS
    *** enhanced by: xMek1(R291A) [substitution]
    *** inhibited by: xMek1(R291K) [substitution]
    *** source: 14993270-Fig-6a

  *** xMek1(mnr)"CA"[Ab]IP IVKA(Erk2)[32P-ATP] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xMek1(mnr)"CA-del(265-301)" [substitution]
    *** source: 9677429-Fig-2f
