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Transcription
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Eps15-- ???

  *** Ifnb1-gene promo-reporter[Luc] is increased irt PolyIC (6 hr)
    *** cells: HEK293<xTLR3> in BMS
    *** inhibited by: xEps15(mnr)"DN" [addition]
    *** source: 16858407-Fig-5d

Hmgb1-- and/or Hmgb2-- and/or Hmgb3--

inhibited by Ikba--  ???

  *** Ifnb1-gene mRNA[RTPCR] is increased irt PolyIC (2 hr)
    *** cells: U373<xCd14> in BMS
    *** enhanced by: xIkba(S32A/S36A)"DN" [addition]
    *** source: 22065573-Fig-1e

Ikke--

  *** Ifnb1-gene mRNA[RTPCR] is increased irt PolyIC (tnr)
    *** cells: HELA in BMS
    *** reqs: Ikke [RNAi]
    *** source: 17142768-Fig-7a

Irf7--

  *** Ifnb1-gene mRNA[RTPCR] is increased irt PolyIC (times)
    *** cells: mBMMs in BMS "immortalized"
    *** times: 0 2+ 4++ hr
    *** reqs: Irf7 [RNAi]
    *** source: 22065573-Fig-7c

not Peli--

  *** Ifnb1-gene mRNA[RTPCR] is increased irt PolyIC (times)
    *** cells: mEFs in BMLS
    *** times: 0 2++ 4+ hr
    *** does not req: Peli1 [KO]
    *** source: 19734906-Fig-2a

not Pkr--

  *** Ifnb1-gene mRNA[RPA] is increased irt PolyIC-transfection (4 hr)
    *** cells: mEFs in BMLS
    *** does not req: Pkr [KO]
    *** source: 11113181-Fig-7a

Rela--  ???

  *** Ifnb1-gene promo-reporter[Luc] is increased irt PolyIC (6 hr)
    *** cells: HEK293<xTLR3> in BMS
    *** enhanced by: xRela [addition]
    *** source: 22065573-Fig-4a

inhibited by Rel--  ???

  *** Ifnb1-gene promo-reporter[Luc] is increased irt PolyIC (6 hr)
    *** cells: HEK293<xTLR3> in BMS
    *** inhibited by: xRel [addition]
    *** source: 22065573-Fig-4a

inhibited by Relb--  ???

  *** Ifnb1-gene promo-reporter[Luc] is increased irt PolyIC (6 hr)
    *** cells: HEK293<xTLR3> in BMS
    *** inhibited by: xRelb [addition]
    *** source: 22065573-Fig-4a

Tbk1--

  *** Ifnb1-gene mRNA[RTPCR] is increased irt PolyIC (tnr)
    *** cells: HELA in BMS
    *** reqs: Tbk1  [RNAi]
    *** source: 17142768-Fig-7a

inhibited by Tnfaip3--

  *** Ifnb1-gene promo-reporter[Luc] is increased irt PolyIC (3 hr)
    *** cells: HEK293<xTLR3> in BMS
    *** inhibited by: xTnfaip3 [addition]
    *** source: 15661910-Fig-1e

Traf6--  ????

  *** Ifnb1-gene promo-reporter[Luc] is increased irt PolyIC (9 hr)
    *** cells: HEK293<xTLR3> in BMS
    *** inhibited by: xTraf6(mnr)"T6CT" [addition]
    *** unaffected by: xTraf2(mnr)"T2CT" [addition]
    *** source: 14530355-Fig-3b

Trif--

  *** Ifnb1-gene mRNA[RTPCR] is increased irt PolyIC (2 hr)
    *** cells: mBMMs in BMS "immortalized"
    *** reqs: Trif [KO]
    *** source: 22065573-Fig-1a
  *** Ifnb1-gene mRNA[RTPCR] is increased irt PolyIC (tnr)
    *** cells: HELA in BMS
    *** reqs: Trif [RNAi]
    *** source: 17142768-Fig-7a

inhibited by Yy1--

  *** Ifnb1-gene mRNA[RTPCR] is increased irt PolyIC (2 hr)
    *** cells: mBMMs in BMS "immortalized"
    *** repressed by: Yy1 [RNAi]
    *** source: 22065573-Fig-2d
  *** Ifnb1-gene mRNA[RTPCR] is increased irt PolyIC (2 hr)
    *** cells: mBMMs in BMS "immortalized"
    *** repressed by: Yy1 [RNAi]
    *** source: 22065573-Fig-2e
  *** Ifnb1-gene mRNA[RTPCR] is increased irt PolyIC (2 hr)
    *** cells: U373<xCd14> in BMS
    *** inhibited by: xYy1 [addition]
    *** source: 22065573-Fig-5b
  *** Ifnb1-gene promo-reporter[Luc] is increased irt PolyIC (6 hr)
    *** cells: HEK293<xTLR3> in BMS
    *** inhibited by: xYy1 [addition]
    *** source: 22065573-Fig-4a

chemicals

  *** Ifnb1-gene mRNA[RTPCR] is increased irt PolyIC (2 hr)
    *** cells: mBMMs in BMS "immortalized"
    *** enhanced by: JSH23 [pretreatment]
    *** enhanced by: CHX [pretreatment]
    *** source: 22065573-Fig-2a
  *** Ifnb1-gene mRNA[RTPCR] is increased irt PolyIC (2 hr)
    *** cells: mBMMs in BMS "immortalized"
    *** enhanced by: JSH23 [pretreatment]
    *** source: 22065573-Fig-1a
  *** Ifnb1-gene mRNA[RTPCR] is increased irt PolyIC-transfection (tnr)
    *** cells: mEFs in BMS
    *** inhibited by: CpGb-transfection [pretreatment]
    *** source: 19890330-Fig-4a
  *** Ifnb1-gene mRNA[RTPCR] is increased irt PolyIC (4 hr)
    *** cells: mBMMs in BMS
    *** unaffected by: SmacMimetic [pretreatment]
    *** source: 19898473-Fig-6a

no extras

  *** Ifnb1-gene promo-reporter[Luc] is increased irt dsRNA (6 hr)
    *** cells: HEK293<xTLR3> in BMS
    *** comment: dsRNA is a 34 bp sequence derived from human rhinovirus
    *** source: 16858407-Fig-S2b
  *** Ifnb1[Ab] secretion[ELISA] is increased irt dsRNA (8 hr)
    *** cells: hMDDCs in BMS
    *** comment: dsRNA is a 34 bp sequence derived from human rhinovirus
    *** source: 16858407-Fig-S2a
  *** Ifnb1-gene mRNA[RTPCR] is increased irt PolyIC (2 hr)
    *** cells: THP1 in BMS "differentiated with Csf1"
    *** enhanced by: JSH23 [pretreatment]
    *** source: 22065573-Fig-1c

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Translation
===========

  *** Ifnb1[Ab] secretion[ELISA] is increased irt PolyIC (16 hr)
    *** cells: U373<xCd14> in BMS
    *** enhanced by: xRela [addition]
    *** source: 22065573-Fig-4b
  *** Ifnb1[Ab] secretion[ELISA] is increased irt PolyIC (16 hr)
    *** cells: U373<xCd14> in BMS
    *** partially inhibited by: xRelb [addition]
    *** source: 22065573-Fig-4b
  *** Ifnb1[Ab] secretion[ELISA] is increased irt PolyIC (16 hr)
    *** cells: U373<xCd14> in BMS
    *** unaffected by: xRel [addition]
    *** source: 22065573-Fig-4b
