=============
Transcription
=============

Hmgb1-- and/or Hmgb2-- and/or Hmgb3--

  *** IL6-gene mRNA[RTPCR] is increased irt PolyIC-transfection (6 hr)
    *** cells: mEFs in BMS
    *** partially reqs: Hmgb1 [KO]
    *** source: 19890330-Fig-S2b
  *** IL6-gene mRNA[RTPCR] is increased irt PolyIC-transfection (6 hr)
    *** cells: mEFs in BMS
    *** partially reqs: Hmgb1 and/or Hmgb2 and/or Hmgb3 [RNAi]
    *** source: 19890330-Fig-S2j
  *** IL6-gene mRNA[RTPCR] is increased irt PolyIC-transfection (6 hr)
    *** cells: mEFs in BMS
    *** partially reqs: Hmgb2 [KO]
    *** source: 19890330-Fig-S2d
  *** IL6-gene mRNA[RTPCR] is increased irt PolyIC-transfection (6 hr)
    *** cells: NIH3T3 in BMS
    *** partially reqs: Hmgb1 and/or Hmgb2 and/or Hmgb3 [RNAi]
    *** source: 19890330-Fig-S2q
  *** IL6-gene mRNA[RTPCR] is increased irt PolyIC-transfection (6 hr)
    *** cells: RAW2647 in BMS
    *** partially reqs: Hmgb1 and/or Hmgb2 and/or Hmgb3 [RNAi]
    *** source: 19890330-Fig-S2o
  *** IL6-gene mRNA[RTPCR] is increased irt PolyIC-transfection (times)
    *** cells: mEFs in BMS
    *** times: 0 3+ 6+ hr
    *** reqs: Hmgb1 and/or Hmgb2 and/or Hmgb3 [KO]
    *** source: 19890330-Fig-1c
  *** IL6-gene mRNA[RTPCR] is increased irt PolyIC-transfection (times)
    *** cells: mEFs in BMS
    *** times: 0 3+ 6++ hr
    *** partially reqs: Hmgb1 [KO]
    *** source: 19890330-Fig-S2a
  *** IL6-gene mRNA[RTPCR] is increased irt PolyIC-transfection (times)
    *** cells: mFLcDCs in BMS
    *** times: 0 3++ 6+ hr
    *** partially reqs: Hmgb1 [KO]
    *** source: 19890330-Fig-3a
  *** IL6-gene mRNA[RTPCR] is increased irt PolyIC-transfection (times)
    *** cells: mFLcDCs in BMS
    *** times: 0 3++ 6+ hr
    *** partially reqs: Hmgb1 [KO]
    *** source: 19890330-Fig-S1c
  *** IL6-gene mRNA[RTPCR] is increased irt PolyIC-transfection (times)
    *** cells: RAW2647 in BMS
    *** times: 0 3+ 6++ hr
    *** reqs: Hmgb1 and/or Hmgb2 and/or Hmgb3 [KO]
    *** source: 19890330-Fig-S5a

MsR1--

  *** IL6-gene mRNA[RTPCR] is increased irt PolyIC (2 hr)
    *** cells: BEAS2B in BMS
    *** inhibited by: anti-MsR1 [pretreatment]
    *** source: 17709607-Fig-2a
  *** IL6-gene mRNA[RTPCR] is increased irt PolyIC (2 hr)
    *** cells: hBECs in BMLS
    *** inhibited by: anti-MsR1 [pretreatment]
    *** source: 17709607-Fig-2b

not Pkr--

  *** IL6-gene mRNA[RPA] is increased irt PolyIC-transfection (4 hr)
    *** cells: mEFs in BMLS
    *** does not req: Pkr [KO]
    *** source: 11113181-Fig-7a

chemicals

  *** IL6-gene mRNA[RTPCR] is increased irt PolyIC (2 hr)
    *** cells: BEAS2B in BMS
    *** inhibited by: DextranSulfate [cotreatment]
    *** inhibited by: Fucoidan [cotreatment]
    *** inhibited by: Ac-LDL [cotreatment]
    *** unaffected by: Heparin [cotreatment]
    *** unaffected by: Fetuin [cotreatment]
    *** source: 17709607-Fig-1a
  *** IL6-gene mRNA[RTPCR] is increased irt PolyIC (2 hr)
    *** cells: hBECs in BMLS
    *** inhibited by: DextranSulfate [cotreatment]
    *** source: 17709607-Fig-1c
  *** IL6-gene mRNA[RTPCR] is increased irt PolyIC (2 hr)
    *** cells: mBMMs in BMS
    *** unaffected by: SmacMimetic [pretreatment]
    *** source: 19898473-Fig-6a


=========
Secretion
=========

Hmgb1-- and/or Hmgb2-- and/or Hmgb3--

  *** IL6[Ab] secretion[ELISA] is increased irt PolyIC-transfection (6 hr)
    *** cells: mEFs in BMS
    *** partially reqs: Hmgb1 and/or Hmgb2 and/or Hmgb3 [RNAi]
    *** source: 19890330-Fig-S2k

not Pkr--

  *** IL6[Ab] secretion[ELISA] is increased irt PolyIC-transfection (24 hr)
    *** cells: mEFs in BMLS
    *** does not req: Pkr [KO]
    *** source: 11113181-Fig-7b



chemicals

  *** IL6[Ab] secretion[ELISA] is increased irt PolyIC (24 hr)
    *** cells: hMDDCs in BMS
    *** inhibited by: Z-FA-FMK [pretreatment]
    *** source: 23255358-Fig-2e

