Tak1 requires Traf6 to return to cyto

  *** Tak1[Ab] copptby[WB] TLR4[Ab] is increased irt Lps (times)
    *** cells: RAW2647 in BMS "membrane fraction"
    *** times: 0 10+ 30 min
    *** comment: decrease at 30 min reqs Traf6 [RNAi]
    *** comment: decrease at 30 min does not req Traf3 [RNAi]
    *** source: 19898473-Fig-2c

Indication that Ciap1 or Ciap2 is required for return to cyto

  *** Tak1[Ab] copptby[WB] TLR4[Ab] is increased irt Lps (times)
    *** cells: mBMMs in BMS "membrane fraction"
    *** times: 0 10+ 30 min
    *** comment: pretreatment with SmacMimetic prevented decrease at 30 min
    *** comment: coppt Tak1 is not phosed on T184/T187
    *** source: 19898473-Fig-2a


