*** A2m--    
*** Akt1--
  *** Akt1[phosAb] phos(S473)[phosAb] is unchanged irt IL6 (30 min)
    *** cells: HEPG2 in BMLS "plated on collagen"
    *** source: 19953085-Fig-S1
  *** Bak1-gene mRNA[RPA] is decreased irt IL6 (6 hr)
    *** cells: KAS61 in BMS "IL6 deprived for 24 hr"
    *** reversed by: 15dPGJ2 [cotreatment]
    *** reversed by: Troglitazone [cotreatment]
    *** unaffected by: Troglitazone + GW9662 [cotreatment]
    *** unaffected by: WY14643 [cotreatment]
    *** source: 14975242-Fig-2d
  *** Bax-gene mRNA[RPA] is decreased irt IL6 (6 hr)
    *** cells: KAS61 in BMS "IL6 deprived for 24 hr"
    *** reversed by: 15dPGJ2 [cotreatment]
    *** reversed by: Troglitazone [cotreatment]
    *** unaffected by: Troglitazone + GW9662 [cotreatment]
    *** unaffected by: WY14643 [cotreatment]
    *** source: 14975242-Fig-2d
  *** Bcl2-gene mRNA[RPA] is detectable-but unchanged irt IL6 (6 hr)
    *** cells: KAS61 in BMS "IL6 deprived for 24 hr"
    *** inhibited by: 15dPGJ2 [cotreatment]
    *** inhibited by: Troglitazone [cotreatment]
    *** unaffected by: Troglitazone + GW9662 [cotreatment]
    *** unaffected by: WY14643 [cotreatment]
    *** source: 14975242-Fig-2e
  *** Bclxl-gene mRNA[RPA] is increased irt IL6 (6 hr)
    *** cells: KAS61 in BMS "IL6 deprived for 24 hr"
    *** inhibited by: 15dPGJ2 [cotreatment]
    *** partially inhibited by: Troglitazone [cotreatment]
    *** unaffected by: Troglitazone + GW9662 [cotreatment]
    *** unaffected by: WY14643 [cotreatment]
    *** source: 14975242-Fig-2e
  *** Cdkn1a-gene mRNA[RPA] is decreased irt IL6 (6 hr)
    *** cells: KAS61 in BMS "IL6 deprived for 24 hr"
    *** reversed by: 15dPGJ2 [cotreatment]
    *** reversed by: Troglitazone [cotreatment]
    *** unaffected by: Troglitazone + GW9662 [cotreatment]
    *** unaffected by: WY14643 [cotreatment]
    *** source: 14975242-Fig-2d
*** Creb1--
  *** Creb1[phosAb] phos(S133)[phosAb] is increased irt IL6 (30 min)
    *** cells: HEPG2 in BMLS "plated on collagen"
    *** unaffected by: Gefitinib [cotreatment]
    *** unaffected by: BMS345541 [cotreatment]
    *** partially inhibited by: PD325901 [cotreatment]
    *** unaffected by: PHA818637 [cotreatment]
    *** unaffected by: ZSTK474 [cotreatment]
    *** source: 19953085-Fig-S1
*** Csf3--
  *** Csf3[125I] receptor-binding[RIA] is undetectable
    *** cells: BAFB03<IL6R~null><xGp130> in BMS
    *** comment: Csf3 is from human
    *** source: 2261637-Fig-5a
  *** Defb1-gene mRNA[RTPCR] is unchanged irt IL6 (18 hr)
    *** cells: hHepatocytes in BMS
    *** source: 15308104-Fig-S1a
  *** Defb4a-gene mRNA[RTPCR] is unchanged irt IL6 (18 hr)
    *** cells: hHepatocytes in BMS
    *** source: 15308104-Fig-S1a
  *** Defb103a-gene mRNA[RTPCR] is unchanged irt IL6 (18 hr)
    *** cells: hHepatocytes in BMS
    *** source: 15308104-Fig-S1a
  *** E2f1-gene mRNA[RPA] is increased irt IL6 (6 hr)
    *** cells: KAS61 in BMS "IL6 deprived for 24 hr"
    *** inhibited by: 15dPGJ2 [cotreatment]
    *** inhibited by: Troglitazone [cotreatment]
    *** unaffected by: Troglitazone + GW9662 [cotreatment]
    *** unaffected by: WY14643 [cotreatment]
    *** source: 14975242-Fig-2b
  *** E2f2-gene mRNA[RPA] is increased irt IL6 (6 hr)
    *** cells: KAS61 in BMS "IL6 deprived for 24 hr"
    *** inhibited by: 15dPGJ2 [cotreatment]
    *** inhibited by: Troglitazone [cotreatment]
    *** unaffected by: Troglitazone + GW9662 [cotreatment]
    *** unaffected by: WY14643 [cotreatment]
    *** source: 14975242-Fig-2b
  *** E2f4-gene mRNA[RPA] is increased irt IL6 (6 hr)
    *** cells: KAS61 in BMS "IL6 deprived for 24 hr"
    *** inhibited by: 15dPGJ2 [cotreatment]
    *** inhibited by: Troglitazone [cotreatment]
    *** unaffected by: Troglitazone + GW9662 [cotreatment]
    *** unaffected by: WY14643 [cotreatment]
    *** source: 14975242-Fig-2b
*** Egr1--
  *** Egr1-gene mRNA[Northern] is increased irt IL6 (times)
    *** cells: M1 in BMS
    *** times: 0 1+ 6++ 24+ hr
    *** unaffected by: xStat1(Y701F) [addition]
    *** unaffected by: xStat3(Y705F) [addition]
    *** unaffected by: xStat3(E434A/E435A) [addition]
    *** source: 8670868-Fig-7
  *** Egr1-gene mRNA[Northern] is increased irt IL6 (times)
    *** cells: M1 in BMS
    *** times: 0 4+ 24 hr
    *** unaffected by: xPtprec [addition]
    *** unaffected by: xPtprec(D245A) [addition]
    *** source: 10859312-Fig-4
*** Erks--
*** Foxo1--
  *** Foxo1[Ab] locatedin(nucleus)[IHC] is detectable-but unchanged irt IL6 (10 min)
    *** cells: HEPG2 in BMLS "pretreated with LY294002"
    *** source: 12456685-Fig-5
  *** Foxo1[phosAb] phos(sitenr)[phosAb] is increased irt IL6 (tnr)
    *** cells: MM1S in BMLS
    *** bkg inhibited by: PP2 [pretreatment]
    *** unaffected by: PP3 [pretreatment]
    *** source: 15010462-Fig-7d
  *** Foxo1[phosAb] phos(T24)[phosAb] is unchanged irt IL6 (15 min) 
    *** cells: HEPG2 in BMLS
    *** source: 12456685-Fig-3c
  *** Foxo1[phosAb] phos(T256)[phosAb] is unchanged irt IL6 (15 min) 
    *** cells: HEPG2 in BMLS
    *** source: 12456685-Fig-3c
*** Gab1--
*** Gab2--
*** Gp130--
  *** Gp130-gene mRNA[RPA] is detectable-but unchanged irt IL6 (6 hr)
    *** cells: KAS61 in BMS "IL6 deprived for 24 hr"
    *** unaffected by: 15dPGJ2 [cotreatment]
    *** unaffected by: Troglitazone [cotreatment]
    *** unaffected by: Troglitazone + GW9662 [cotreatment]
    *** unaffected by: WY14643 [cotreatment]
    *** source: 14975242-Fig-3a
  *** Gp130[Ab]IP IVLKA(PtdIns)[32P-ATP] is unchanged irt IL6 (10 min)
    *** cells: HEPG2 in BMS
    *** source: 9632795-Fig-1d
  *** Gp130[Ab]IP Yphos[pYAb] is increased irt IL6 (times)
    *** cells: H35 in BMS
    *** times: 0 5+ 15+ 30 60 120 180 240 min
    *** source: 10409724-Fig-2a
*** Grb2--
  *** Grb2[Ab] copptby[WB] Gab1[Ab] is unchanged irt IL6 (2 min)
    *** cells: MM1S in BMLS
    *** source: 15010462-Fig-2b
  *** Grb2[Ab] copptby[WB] Gab2[Ab] is unchanged irt IL6 (2 min)
    *** cells: MM1S in BMLS
    *** source: 15010462-Fig-2b
*** GRR-reporter--
  *** GRR-reporter[Luc] is increased irt IL6 (2 hr)
    *** cells: HEPG2 in BMS
    *** unaffected by: anti-IL10Rb [pretreatment]
    *** source: 10954742-Fig-5b
  *** Gsk3s[phosAb] phos(SFAE)[phosAb] is unchanged irt IL6 (30 min)
    *** cells: HEPG2 in BMLS "plated on collagen"
    *** source: 19953085-Fig-S1
*** Hck--
*** Hif1a--
  *** Hif1a[Ab] prot-exp[ELISA] is unchanged irt IL6 (times)
    *** cells: hUVECs in BMS
    *** times: 0 4 24 hr
    *** source: 18606657-Fig-1a
*** Hp--
  *** Hp-gene mRNA[Northern] is increased irt IL6 (8 hr)
    *** cells: HEPG2 in BMS
    *** partially reqs: Lmo4 [RNAi]
    *** source: 15677447-Fig-7g
  *** Hspb1[phosAb] phos(S78)[phosAb] is unchanged irt IL6 (30 min)
    *** cells: HEPG2 in BMLS "plated on collagen"
    *** source: 19953085-Fig-S1
*** Ifng--
  *** Ifng-gene mRNA[RPA] is unchanged irt IL6 (4 hr)
    *** cells: mBMNKs<Rag1~null> in BMS
    *** source: 10229825-Fig-1b
  *** Ifng[Ab] secretion[ELISA] is unchanged irt IL6 (4 hr)
    *** cells: mBMNKs<Rag1~null> in BMS
    *** source: 10229825-Fig-1a
  *** Ikba[phosAb] phos(S32/S36)[phosAb] is unchanged irt IL6 (30 min)
    *** cells: HEPG2 in BMLS "plated on collagen"
    *** source: 19953085-Fig-S1
*** IL2--
  *** IL2[125I] receptor-binding[RIA] is undetectable
    *** cells: BAFB03<IL6R~null><xGp130> in BMS
    *** comment: IL2 is from human
    *** source: 2261637-Fig-5a
*** IL3--
  *** IL3[125I] receptor-binding[RIA] is detectable
    *** cells: BAFB03<IL6R~null><xGp130> in BMS
    *** comment: reqs that the IL3 be from mouse and not human
    *** source: 2261637-Fig-5a
  *** IL6R-gene mRNA[RPA] is detectable-but unchanged irt IL6 (6 hr)
    *** cells: KAS61 in BMS "IL6 deprived for 24 hr"
    *** unaffected by: 15dPGJ2 [cotreatment]
    *** unaffected by: Troglitazone [cotreatment]
    *** unaffected by: Troglitazone + GW9662 [cotreatment]
    *** unaffected by: WY14643 [cotreatment]
    *** source: 14975242-Fig-3a
*** IL23R--
  *** IL23R-gene mRNA[RTPCR] is increased irt IL6 (48 hr)
    *** cells: mSpNaiveCD4TCs in BMS "containing anti-Cd3 + anti-Cd28"
    *** comment: enhanced by low concs of Tgfb1
    *** source: 18368049-Fig-4b
  *** IL23R-gene mRNA[RTPCR] is increased irt IL6 (48 hr)
    *** cells: mSpNaiveCD4TCs<xCxcL9> in BMS
    *** inhibited by: xFoxp3 [substitution]
    *** partially inhibited by: xFoxp3(mnr)"exon2-deleted" [substitution]
    *** source: 18368049-Fig-4a
  *** IL23R-gene mRNA[RTPCR] is increased irt IL6 (48 hr)
    *** cells: mSpNaiveCD4TCs in BMS "containing anti-Cd3 + anti-Cd28"
    *** inhibited by: Tgfb1 [cotreatment]
    *** enhanced by: IL21 [cotreatment]
    *** source: 17581537-Fig-1b
  *** IL23R-gene mRNA[RTPCR] is increased irt IL6 (48 hr)
    *** cells: mSpNaiveCD4TCs in BMS "containing anti-Cd3 + anti-Cd28"
    *** inhibited by: Tgfb1 [cotreatment]
    *** unaffected by: IL21 [cotreatment]
    *** source: 17581537-Fig-4d
  *** IL23R-gene mRNA[RTPCR] is increased irt IL6 (48 hr)
    *** cells: mSpNaiveCD4TCs in BMS "containing anti-Cd3 + anti-Cd28"
    *** inhibited by: Tgfb1 [cotreatment]
    *** unaffected by: IL21 [cotreatment]
    *** source: 17581537-Fig-5c
  *** IL23R-gene mRNA[RTPCR] is increased irt IL6 (48 hr)
    *** cells: mSpNaiveCD4TCs in BMS "containing anti-Cd3 + anti-Cd28"
    *** reqs: IL21R [KO]
    *** source: 17581537-Fig-4d
  *** IL23R-gene mRNA[RTPCR] is increased irt IL6 (48 hr)
    *** cells: mSpNaiveCD4TCs in BMS "containing anti-Cd3 + anti-Cd28"
    *** reqs: RoRc [KO]
    *** source: 17581537-Fig-1b
  *** IL23R-gene mRNA[RTPCR] is increased irt IL6 (48 hr)
    *** cells: mSpNaiveCD4TCs in BMS "containing anti-Cd3 + anti-Cd28"
    *** reqs: Stat3 [KO]
    *** source: 17581537-Fig-5c
*** Irf1--
  *** Irs1[phosAb] phos(S636/S639)[phosAb] is increased irt IL6 (30 min)
    *** cells: HEPG2 in BMLS "plated on collagen"
    *** unaffected by: Gefitinib [cotreatment]
    *** unaffected by: BMS345541 [cotreatment]
    *** partially inhibited by: PD325901 [cotreatment]
    *** unaffected by: PHA818637 [cotreatment]
    *** unaffected by: ZSTK474 [cotreatment]
    *** source: 19953085-Fig-S1
*** Jak1--
*** Jak2--
*** Jak3--
  *** Jak3[Ab]IP Yphos[pYAb] is unchanged irt (IL6 + IL6Rsol) (15 min)
    *** cells: 2C4 in BMS
    *** source: 7537214-Fig-7b
  *** Jnks[phosAb] phos(TPY)[phosAb] is unchanged irt IL6 (30 min)
    *** cells: HEPG2 in BMLS "plated on collagen"
    *** source: 19953085-Fig-S1
  *** Jun[phosAb] phos(S63)[phosAb] is unchanged irt IL6 (30 min)
    *** cells: HEPG2 in BMLS "plated on collagen"
    *** source: 19953085-Fig-S1
*** Lbp--
  *** Lbp-gene mRNA[Northern] is increased irt IL6 (24 hr)
    *** cells: HUH7 in BMS
    *** enhanced by: Dexamethasone [cotreatment]
    *** source: 8668165-Fig-1d
*** LifR--
  *** LifR[Ab]IP Yphos[pYAb] is unchanged irt (IL6 + IL6Rsol) (5 min)
    *** cells: EW1 in BMLS
    *** source: 8272873-Fig-1a
*** Lmo4--
  *** Lmo4[Ab] copptby[WB] Gp130[Ab] is detectable-but unchanged irt IL6 (30 min)
    *** cells: T47D in BMS
    *** source: 15677447-Fig-2c
  *** Lmo4[Ab] copptby[WB] Jak1[Ab] is increased irt IL6 (30 min)
    *** cells: T47D in BMS
    *** source: 15677447-Fig-2c
  *** Lmo4[Ab] copptby[WB] Shp2[Ab] is detectable-but unchanged irt IL6 (30 min)
    *** cells: HEPG2 in BMS
    *** source: 15677447-Fig-3b
  *** Lmo4[Ab] copptby[WB] Shp2[Ab] is detectable-but unchanged irt IL6 (30 min)
    *** cells: T47D in BMS
    *** source: 15677447-Fig-3b
  *** Lmo4[Ab] copptby[WB] Stat3[Ab] is unchanged irt IL6 (30 min)
    *** cells: T47D in BMS
    *** source: 15677447-Fig-2c
  *** xLmo4[tAb] copptby[WB] Gp130[Ab] is increased irt IL6 (30 min)
    *** cells: HEPG2 in BMS
    *** source: 15677447-Fig-2a
  *** xLmo4[tAb] copptby[WB] Gp130[Ab] is increased irt IL6 (30 min)
    *** cells: HEPG2<xLmo4> in BMS
    *** source: 15677447-Fig-4
  *** xLmo4[tAb] copptby[WB] Jak1[Ab] is increased irt IL6 (30 min)
    *** cells: HEPG2 in BMS
    *** source: 15677447-Fig-2a
  *** Mcl1-gene mRNA[RPA] is detectable-but unchanged irt IL6 (6 hr)
    *** cells: KAS61 in BMS "IL6 deprived for 24 hr"
    *** inhibited by: 15dPGJ2 [cotreatment]
    *** partially inhibited by: Troglitazone [cotreatment]
    *** unaffected by: Troglitazone + GW9662 [cotreatment]
    *** unaffected by: WY14643 [cotreatment]
    *** source: 14975242-Fig-2e
*** Mcp6--
  *** Mcp6-gene promo-reporter[Luc] is unchanged irt (IL6 + IL6Rsol) (6 hr) 
    *** cells: NIH3T3<xMitf> in BMS
    *** unaffected by: xMitf(S409A) [substitution]
    *** source: 15572665-Fig-2c
  *** Mek12s[phosAb] phos(SMANS)[phosAb] is unchanged irt IL6 (30 min)
    *** cells: HEPG2 in BMLS "plated on collagen"
    *** source: 19953085-Fig-S1
*** Mitf--
  *** Mitf[Ab] copptby[WB] Pias3[Ab] is decreased irt (IL6 + IL6Rsol) (15 min)
    *** cells: B16 in BMS
    *** source: 15572665-Fig-7b
  *** Mitf[Ab] copptby[WB] Pias3[Ab] is decreased irt (IL6 + IL6Rsol) (tnr)
    *** cells: mBMMastCs in BMS "IL3-deprived"
    *** source: 15572665-Fig-6b
  *** xMitf[Ab] copptby[WB] xPias3[Ab] is decreased irt (IL6 + IL6Rsol) (15 min)
    *** cells: NIH3T3 in BMS
    *** reversed by: xMitf(S409A) [substitution]
    *** source: 15572665-Fig-2b
  *** xMitf[Ab]IP Sphos[pSAb] is increased irt (IL6 + IL6Rsol) (15 min)
    *** cells: NIH3T3 in BMS
    *** unaffected by: xMitf(S73A) [substitution]
    *** unaffected by: xMitf(S409A) [substitution]
    *** inhibited by: xMitf(S73A/S409A) [substitution]
    *** source: 15572665-Fig-2a
  *** Mitf[Ab]IP Sphos[pSAb] is increased irt (IL6 + IL6Rsol) (tnr)
    *** cells: mBMMastCs in BMS "IL3-deprived"
    *** source: 15572665-Fig-6a
*** Mkk4--
*** Myb--
  *** Myb-gene mRNA[Northern] is decreased irt IL6 (times)
    *** cells: M1 in BMS
    *** times: 0++ 1++ 6+ 24 hr
    *** unaffected by: xStat1(Y701F) [addition]
    *** reversed by: xStat3(Y705F) [addition]
    *** reversed by: xStat3(E434A/E435A) [addition]
    *** source: 8670868-Fig-7
*** Myc--
  *** Myc-gene mRNA[Northern] is decreased irt IL6 (times)
    *** cells: M1 in BMS
    *** times: 0+ 4+ 24 hr
    *** reversed by: xPtprec [addition]
    *** unaffected by: xPtprec(D245A) [addition]
    *** source: 10859312-Fig-4
  *** Myc-gene mRNA[Northern] is decreased irt IL6 (times)
    *** cells: M1 in BMS
    *** times: 0++ 1++ 6+ 24 hr
    *** unaffected by: xStat1(Y701F) [addition]
    *** reversed by: xStat3(Y705F) [addition]
    *** reversed by: xStat3(E434A/E435A) [addition]
    *** source: 8670868-Fig-7
  *** Myc-gene mRNA[RTPCR] is increased irt IL6 (6 hr)
    *** cells: KAS61 in BMS "IL6 deprived for 24 hr"
    *** inhibited by: 15dPGJ2 [cotreatment]
    *** inhibited by: Troglitazone [cotreatment]
    *** unaffected by: WY14643 [cotreatment]
    *** source: 14975242-Fig-2b
  *** Ncor2[Ab] copptby[WB] Pparg[Ab] is detectable-but unchanged irt IL6 (10 min)
    *** unaffected by: 15dPGJ2 [pretreatment]
    *** inhibited by: Troglitazone [pretreatment]
    *** comment: no way to tell whether coppt or Ncor2 prot-exp is inhibited here
    *** unaffected by: Troglitazone + GW9662 [pretreatment]
    *** source: 14975242-Fig-6c
*** Nos2a--
  *** Nos2a-gene mRNA[Northern] is increased irt IL6 (3 days)
    *** cells: M1 in BMS
    *** inhibited by: xStat3(Y705F) [addition]
    *** inhibited by: xStat3(E434A/E435A) [addition]
    *** unaffected by: xStat1(Y701F) [addition]
    *** source: 8670868-Fig-3
*** P38--
  *** P38s[phosAb] phos(TGY)[phosAb] is detectable-but unchanged irt IL6 (times)
    *** cells: J774E in BMLS
    *** times: 0+ 2+ 5+ 10+ 20+ 30+ min
    *** source: 16763563-Fig-3b
  *** P38s[phosAb] phos(TGY)[phosAb] is increased irt IL6 (30 min)
    *** cells: HEPG2 in BMLS "plated on collagen"
    *** partially inhibited by: Gefitinib [cotreatment]
    *** inhibited by: BMS345541 [cotreatment]
    *** partially inhibited by: PD325901 [cotreatment]
    *** unaffected by: PHA818637 [cotreatment]
    *** partially inhibited by: ZSTK474 [cotreatment]
    *** source: 19953085-Fig-S1
  *** Pi3k[phosAb] phos(sitenr)[phosAb] is increased irt IL6 (10 min)
    *** cells: KAS61 in BMS "IL6 deprived for 24 hr"
    *** unaffected by: 15dPGJ2 [pretreatment]
    *** unaffected by: Troglitazone [pretreatment]
    *** unaffected by: Troglitazone + GW9662 [pretreatment]
    *** unaffected by: WY14643 [pretreatment]
    *** source: 14975242-Fig-3c
  *** Pias3[Ab] prot-exp[WB] is detectable-but unchanged irt IL6 (10 min)
    *** cells: KAS61 in BMS "IL6 deprived for 24 hr"
    *** unaffected by: 15dPGJ2 [pretreatment]
    *** unaffected by: Troglitazone [pretreatment]
    *** unaffected by: Troglitazone + GW9662 [pretreatment]
    *** unaffected by: WY14643 [pretreatment]
    *** source: 14975242-Fig-6e
*** Pik3r--
  *** Pik3rs[Ab] copptby[WB] Gab1[Ab] is increased irt IL6 (10 min)
    *** cells: HEPG2 in BMS
    *** source: 9632795-Fig-1c
  *** Pik3rs[Ab] copptby[WB] Gab1[Ab] is increased irt IL6 (times)
    *** cells: HEPG2 in BMS
    *** times: 0 5++ 10++ 30+ 60 min
    *** source: 9632795-Fig-1a
  *** Pik3rs[Ab] copptby[WB] Gp130[Ab] is unchanged irt IL6 (10 min)
    *** cells: HEPG2 in BMS
    *** source: 9632795-Fig-1c
  *** Pik3rs[Ab] copptby[WB] Shp2[Ab] is increased irt IL6 (10 min)
    *** cells: HEPG2 in BMS
    *** source: 9632795-Fig-1c
*** Pkcd--
  *** Pparg[Ab]IP prot-exp[WB] is detectable-but unchanged irt IL6 (10 min)
    *** cells: KAS61 in BMS "IL6 deprived for 24 hr"
    *** unaffected by: 15dPGJ2 [pretreatment]
    *** unaffected by: Troglitazone [pretreatment]
    *** source: 14975242-Fig-6a
  *** Pparg[Ab]IP prot-exp[WB] is detectable-but unchanged irt IL6 (10 min)
    *** cells: KAS61 in BMS "IL6 deprived for 24 hr"
    *** unaffected by: 15dPGJ2 [pretreatment]
    *** unaffected by: Troglitazone [pretreatment]
    *** unaffected by: Troglitazone + GW9662 [pretreatment]
    *** source: 14975242-Fig-6c
*** Proliferation--
  *** Proliferation[CellNumber] is decreased irt IL6 (3 days)
    *** cells: M1 in BMS
    *** unaffected by: xStat1(Y701F) [addition]
    *** reversed by: xStat3(Y705F) [addition]
    *** reversed by: xStat3(E434A/E435A) [addition]
    *** source: 8670868-Fig-4
*** Rab4--
  *** Rab4?-gene mRNA[RTPCR] is unchanged irt IL6 (times)
    *** cells: J774E in BMLS
    *** times: 0+ 1+ 2+ 3+ 4+ 5+ 6+ hr
    *** source: 16763563-Fig-2c
  *** Rab4s[Ab] prot-exp[WB] is unchanged irt IL6 (times)
    *** cells: J774E in BMLS
    *** times: 0+ 2+ 4+ 6+ hr
    *** comment: cells were incubated for 3 hr in BMS after stimulus
    *** source: 16763563-Fig-2a
*** Rab5--
  *** Rab5a-gene mRNA[RTPCR] is increased irt IL6 (times)
    *** cells: J774E in BMLS
    *** times: 0+ 1+ 2+ 3++ 4++ 5++ 6++ hr
    *** source: 16763563-Fig-2c
  *** Rab5b-gene mRNA[RTPCR] is increased irt IL6 (times)
    *** cells: J774E in BMLS
    *** times: 0+ 1+ 2+ 3+ 4+ 5++ 6++ hr
    *** source: 16763563-Fig-2c
  *** Rab5c-gene mRNA[RTPCR] is increased irt IL6 (6 hr)
    *** cells: J774E in BMLS
    *** unaffected by: Genistein [pretreatment]
    *** unaffected by: Wortmannin [pretreatment]
    *** unaffected by: LY294002 [pretreatment]
    *** inhibited by: PD98059 [pretreatment]
    *** inhibited by: U0126 [pretreatment]
    *** unaffected by: SB203580 [pretreatment]
    *** unaffected by: SP600125 [pretreatment]
    *** source: 16763563-Fig-3a
  *** Rab5c-gene mRNA[RTPCR] is increased irt IL6 (times)
    *** cells: J774E in BMLS
    *** times: 0+ 1++ 2++ 3++ 4++ 5+++ 6+++ hr
    *** source: 16763563-Fig-2c
  *** Rab5c-gene promo-reporter[Luc] is increased irt IL6 (8 hr)
    *** cells: J774E in BMLS
    *** inhibited by: PD98059 [pretreatment]
    *** unaffected by: SB203580 [pretreatment]
    *** source: 16763563-Fig-4b
  *** Rab5c-gene promo-reporter[Luc] is increased irt IL6 (8 hr)
    *** cells: J774E in BMLS
    *** source: 16763563-Fig-4a
  *** Rab5c-gene promo-reporter[Luc] is unchanged irt IL6 (8 hr)
    *** cells: J774E in BMLS
    *** source: 16763563-Fig-4a
  *** Rab5s[Ab] prot-exp[WB] is increased irt IL6 (6 hr)
    *** cells: J774E in BMLS
    *** comment: cells were incubated for 3 hr in BMS after stimulus
    *** source: 16763563-Fig-1a
  *** Rab5s[Ab] prot-exp[WB] is increased irt IL6 (times)
    *** cells: J774E in BMLS
    *** times: 0+ 2++ 4++ 6++ hr
    *** comment: cells were incubated for 3 hr in BMS after stimulus
    *** source: 16763563-Fig-2a
*** Rab6--
  *** Rab6?-gene mRNA[RTPCR] is unchanged irt IL6 (times)
    *** cells: J774E in BMLS
    *** times: 0+ 1+ 2+ 3+ 4+ 5+ 6+ hr
    *** source: 16763563-Fig-2c
  *** Rab6s[Ab] prot-exp[WB] is unchanged irt IL6 (times)
    *** cells: J774E in BMLS
    *** times: 0+ 2+ 4+ 6+ hr
    *** comment: cells were incubated for 3 hr in BMS after stimulus
    *** source: 16763563-Fig-2a
*** Rab7--
  *** Rab7?-gene mRNA[RTPCR] is unchanged irt IL6 (times)
    *** cells: J774E in BMLS
    *** times: 0+ 1+ 2+ 3+ 4+ 5+ 6+ hr
    *** source: 16763563-Fig-2c
  *** Rab7s[Ab] prot-exp[WB] is unchanged irt IL6 (6 hr)
    *** cells: J774E in BMLS
    *** comment: cells were incubated for 3 hr in BMS after stimulus
    *** source: 16763563-Fig-1a
  *** Rab7s[Ab] prot-exp[WB] is unchanged irt IL6 (times)
    *** cells: J774E in BMLS
    *** times: 0+ 2+ 4+ 6+ hr
    *** comment: cells were incubated for 3 hr in BMS after stimulus
    *** source: 16763563-Fig-2a
*** Rab11--
  *** Rab11s[Ab] prot-exp[WB] is unchanged irt IL6 (times)
    *** cells: J774E in BMLS
    *** times: 0+ 2+ 4+ 6+ hr
    *** comment: cells were incubated for 3 hr in BMS after stimulus
    *** source: 16763563-Fig-2a
*** Rac1--
*** RankL--
*** RoRc-- RoRc-gene--
  *** RoRc-gene mRNA[RTPCR] is unchanged irt IL6 (3 days)
    *** cells: hNaiveCD4TCs in BMS
    *** source: 18454151-Fig-2b
  *** RoRc-gene mRNA[RTPCR] is increased irt IL6 (48 hr)
    *** cells: mCD4TCs<xCxcL9> in BMS "containing anti-Cd3 + anti-Cd28"
    *** unaffected by: IL23 [cotreatment]
    *** enhanced by: Tgfb [cotreatment]
    *** source: 17581537-Fig-2c
  *** RoRc-gene mRNA[RTPCR] is increased irt IL6 (48 hr)
    *** cells: mCD4TCs<xIL23R> in BMS "containing anti-Cd3 + anti-Cd28"
    *** enhanced by: IL23 [cotreatment]
    *** enhanced by: Tgfb1 [cotreatment]
    *** source: 17581537-Fig-2c
  *** RoRc[Ab] prot-exp[WB] is increased irt IL6 (48 hr)
    *** cells: mCD4TCs<xIL23R> in BMS "containing anti-Cd3 + anti-Cd28"
    *** enhanced by: Tgfb1 [cotreatment]
    *** unaffected by: IL21 [cotreatment]
    *** source: 17581537-Fig-3c
*** Rsk1--
  *** Rsk1[phosAb] phos(T359/S363)[phosAb] is unchanged irt IL6 (30 min)
    *** cells: HEPG2 in BMLS "plated on collagen"
    *** source: 19953085-Fig-S1
*** Rsks--
  *** Rsks[Ab]IP Sphos[pSAb] is increased irt (IL6 + IL6Rsol) (tnr)
    *** cells: mBMMastCs in BMS "IL3-deprived"
    *** source: 15572665-Fig-6a
  *** S6k1[phosAb] phos(T444/S447)[phosAb] is increased irt IL6 (30 min)
    *** cells: HEPG2 in BMLS "plated on collagen"
    *** unaffected by: Gefitinib [cotreatment]
    *** unaffected by: BMS345541 [cotreatment]
    *** partially inhibited by: PD325901 [cotreatment]
    *** unaffected by: PHA818637 [cotreatment]
    *** unaffected by: ZSTK474 [cotreatment]
    *** source: 19953085-Fig-S1
  *** Saa1[Ab] secretion[ELISA] is increased irt IL6 (48 hr)
    *** cells: hHepatocytes in BMS
    *** source: 15308104-Fig-2d
*** Shp2--
*** Socs3--
*** Stat1--
  *** Stat1[Ab] copptby[WB] Pias1[Ab] is unchanged irt IL6 (15 min)
    *** cells: HEPG2 in BMS
    *** source: 9724754-Fig-4d
  *** Stat1[Ab] copptby[WB] Pias3[Ab] is unchanged irt IL6 (15 min)
    *** cells: HEPG2 in BMS
    *** source: 9724754-Fig-4e
  *** Stat1[Ab] oligo-binding[EMSA] is increased irt IL6 (45 min)
    *** cells: T47D in BMS
    *** source: 7523403-Fig-1a
  *** Stat1[Ab] oligo-binding[EMSA] is unchanged irt IL6 (15 min)
    *** cells: A431 in BMLS "nuclear-extracts"
    *** source: 8140422-Fig-3b
*** Stat3--
  *** Stat3[Ab]IP phos[32Pi] is increased irt IL6 (15 min)
    *** cells: HEPG2 in BMS
    *** source: 10446219-Fig-5a
  *** Stat3[phosAb] phos(sitenr)[phosAb] is increased irt IL6 (15 min)
    *** cells: HEPG2 in BMS
    *** source: 9724754-Fig-4c
  *** Stat3[phosAb] phos(sitenr)[phosAb] is increased irt IL6 (30 min)
    *** cells: mBMMs in BMS
    *** does not req: Socs3 [KO]
    *** source: 12754506-Fig-2
  *** Stat3[phosAb] phos(sitenr)[phosAb] is increased irt IL6 (30 min)
    *** cells: mBMMs in BMS
    *** inhibited by: Ifng [pretreatment]
    *** comment: inhibition by Ifng requires Socs3 [KO]
    *** source: 12754506-Fig-2
  *** Stat3[phosAb] phos(sitenr)[phosAb] is increased irt IL6 (30 min)
    *** cells: mBMMs in BMS
    *** inhibited by: Lps [preconditioning]
    *** source: 12754506-Fig-2
  *** Stat3[phosAb] phos(sitenr)[phosAb] is increased irt IL6 (30 min)
    *** cells: mBMMs in BMS
    *** unaffected by: IL10 [pretreatment]
    *** source: 12754506-Fig-2
  *** Stat3[phosAb] phos(sitenr)[phosAb] is increased irt IL6 (times)
    *** cells: mBMMs in BMS
    *** times: 0 25++ 100+ 400++ min
    *** comment: repressed by Socs3 [KO] at 400 min only
    *** source: 12754506-Fig-1a
  *** Stat3[phosAb] phos(sitenr)[phosAb] is increased irt IL6 (times)
    *** cells: mBMMs<Ifng~null> in BMS
    *** times: 0 25++ 100+ 400++ min
    *** comment: partially reqs Socs1 [KO] at 400 min only
    *** source: 12754506-Fig-1a
  *** Stat3[phosAb] phos(sitenr)[phosAb] is increased irt IL6 (times)
    *** cells: MM1S in BMLS
    *** times: 0 1 5+ 30+ min
    *** unaffected by: PP2 [pretreatment]
    *** source: 15010462-Fig-7a
  *** Stat3[phosAb] phos(sitenr)[phosAb] is increased irt IL6 (times)
    *** cells: mPECs in BMS
    *** times: 0 1+ 3+ 6+ 9+ hr
    *** does not req: Socs3 [KO]
    *** source: 12754507-Fig-3a
*** Stat5s--
  *** Stat5s[Ab] oligo-binding[EMSA] is unchanged irt IL6 (15 min)
    *** cells: HEPG2 in BMS "nuclear-extracts"
    *** source: 8621622-Fig-6
*** DNA-synthesis--
  *** DNA-synthesis[3H-Thymidine] is decreased irt IL6 (70 hr)
    *** cells: M1 in BMS
    *** enhanced by: IL6Rsol [cotreatment]
    *** source: 2788034-Fig-6b
  *** DNA-synthesis[3H-Thymidine] is increased irt (IL6Rsol + IL6) (40 hr)
    *** cells: BAFB03<xGp130> in BMS
    *** reqs: xGp130 [omission]
    *** reqs: IL6Rsol [omission]
    *** source: 2261637-Fig-7
  *** DNA-synthesis[3H-Thymidine] is increased irt (IL6Rsol + IL6) (40 hr)
    *** cells: BAFB03<xGp130> in BMS
    *** unaffected by: xGp130(1-783)"IC141" [substitution]
    *** unaffected by: xGp130(1-735)"IC93" [substitution]
    *** unaffected by: xGp130(1-707)"IC65" [substitution]
    *** inhibited by: xGp130(1-652)"IC10" [substitution]
    *** source: 1662392-Fig-3
  *** DNA-synthesis[3H-Thymidine] is increased irt IL6 (20 hr)
    *** cells: ANBL6 in BMS "IL6 deprived for 24 hr"
    *** inhibited by: 15dPGJ2 [cotreatment]
    *** inhibited by: Troglitazone [cotreatment]
    *** unaffected by: WY14643 [cotreatment]
    *** source: 14975242-Fig-1c
  *** DNA-synthesis[3H-Thymidine] is increased irt IL6 (20 hr)
    *** cells: KAS61 in BMS "IL6 deprived for 24 hr"
    *** inhibited by: 15dPGJ2 [cotreatment]
    *** inhibited by: Troglitazone [cotreatment]
    *** unaffected by: 15dPGJ2 + GW9662 [cotreatment]
    *** source: 14975242-Fig-1f
  *** DNA-synthesis[3H-Thymidine] is increased irt IL6 (20 hr)
    *** cells: KAS61 in BMS "IL6 deprived for 24 hr"
    *** inhibited by: 15dPGJ2 [cotreatment]
    *** inhibited by: Troglitazone [cotreatment]
    *** unaffected by: WY14643 [cotreatment]
    *** source: 14975242-Fig-1b
  *** DNA-synthesis[3H-Thymidine] is increased irt IL6 (20 hr)
    *** cells: OCIMY5<Pparg~null> in BMS "IL6 deprived for 24 hr"
    *** unaffected by: 15dPGJ2 [cotreatment]
    *** unaffected by: Troglitazone [cotreatment]
    *** unaffected by: WY14643 [cotreatment]
    *** source: 14975242-Fig-1d
  *** DNA-synthesis[3H-Thymidine] is increased irt IL6 (48 hr)
    *** cells: MM1S in BMS
    *** enhanced by: xHck [addition]
    *** source: 15010462-Fig-7g
  *** DNA-synthesis[3H-Thymidine] is increased irt IL6 (48 hr)
    *** cells: MM1S in BMS
    *** inhibited by: PP2 [cotreatment]
    *** source: 15010462-Fig-7g
  *** DNA-synthesis[3H-Thymidine] is increased irt IL6 (48 hr)
    *** cells: MM1S<xHck> in BMS
    *** inhibited by: PP2 [cotreatment]
    *** source: 15010462-Fig-7h
  *** DNA-synthesis[3H-Thymidine] is increased irt IL6 (48 hr)
    *** cells: MM1S<xHck> in BMS
    *** partially inhibited by: xHck(K269E) [substitution]
    *** source: 15010462-Fig-7h
  *** DNA-synthesis[3H-Thymidine] is increased irt IL6 (70 hr)
    *** cells: M1 in BMS
    *** comment: concentration of IL6 req is decreased itpo xIL6R or xIL6R(1-403)"delIC"
    *** source: 2788034-Fig-5
*** Tp53--
  *** Tp53[phosAb] phos(S15)[phosAb] is unchanged irt IL6 (30 min)
    *** cells: HEPG2 in BMLS "plated on collagen"
    *** source: 19953085-Fig-S1
*** Tyk2--
  *** xTyk2[Ab] copptby[WB] xShp2[Ab] is detectable-but unchanged irt (IL6 + IL6Rsol) (15 min)
    *** cells: U1A<Tyk2~null><xTyk2> in BMS
    *** source: 9794795-Fig-4c
*** Vavs--
*** IL21--
  *** IL21-gene mRNA[RTPCR] is increased irt IL6 (48 hr)
    *** cells: mSpNaiveCD4TCs in BMS "containing anti-Cd3 + anti-Cd28"
    *** does not req: IL21R [KO]
    *** source: 17581537-Fig-4c
  *** IL21-gene mRNA[RTPCR] is increased irt IL6 (48 hr)
    *** cells: mSpNaiveCD4TCs in BMS "containing anti-Cd3 + anti-Cd28"
    *** does not req: RoRc [KO]
    *** source: 17581537-Fig-1a
  *** IL21-gene mRNA[RTPCR] is increased irt IL6 (48 hr)
    *** cells: mSpNaiveCD4TCs in BMS "containing anti-Cd3 + anti-Cd28"
    *** partially reqs: Stat3 [KO]
    *** source: 17581537-Fig-5b
  *** IL21-gene mRNA[RTPCR] is increased irt IL6 (48 hr)
    *** cells: mSpNaiveCD4TCs in BMS "containing anti-Cd3 + anti-Cd28"
    *** unaffected by: Tgfb1 [cotreatment]
    *** unaffected by: IL21 [cotreatment]
    *** source: 17581537-Fig-1a
  *** IL21-gene mRNA[RTPCR] is increased irt IL6 (48 hr)
    *** cells: mSpNaiveCD4TCs in BMS "containing anti-Cd3 + anti-Cd28"
    *** unaffected by: Tgfb1 [cotreatment]
    *** unaffected by: IL21 [cotreatment]
    *** source: 17581537-Fig-4c
  *** IL21-gene mRNA[RTPCR] is increased irt IL6 (48 hr)
    *** cells: mSpNaiveCD4TCs in BMS "containing anti-Cd3 + anti-Cd28"
    *** unaffected by: Tgfb1 [cotreatment]
    *** unaffected by: IL21 [cotreatment]
    *** source: 17581537-Fig-5b
