=================
Required Proteins
=================

Gsk3b--

  *** Eselectin-gene promo-reporter[Luc] is increased irt IL1b (tnr)
    *** cells: mEFs in BMS
    *** partially reqs: Gsk3b [KO]
    *** source: 10894547-Fig-5e

IL1R1--

  *** Eselectin-gene promo-reporter[Luc] is increased irt IL1b (8 hr)
    *** cells: HELA<xIL1R1> in BMS
    *** inhibited by: xIL1R1(1-524) [substitution]
    *** source: 9430229-Fig-4a
  *** Eselectin-gene promo-reporter[Luc] is increased irt IL1b (6 hr)
    *** cells: HEK293 in BMS
    *** enhanced by: xIL1R1 [addition]
    *** source: 9371760-Fig-1a

IL1Rap--

  *** Eselectin-gene promo-reporter[Luc] is increased irt IL1b (8 hr)
    *** cells: HELA<xIL1Rap> in BMS
    *** inhibited by: xIL1Rap(1-533) [substitution]
    *** source: 9430229-Fig-4a
  *** Eselectin-gene promo-reporter[Luc] is increased irt IL1b (6 hr)
    *** cells: HELA in BMS
    *** inhibited by: xIL1Rap(1-403) [addition]
    *** source: 9371760-Fig-4b
  *** Eselectin-gene promo-reporter[Luc] is increased irt IL1b (6 hr)
    *** cells: HEK293 in BMS
    *** enhanced by: xIL1Rap [addition]
    *** source: 9371760-Fig-1a

Irak1--

  *** Eselectin-gene promo-reporter[Luc] is increased irt IL1b (6 hr)
    *** cells: HEK293I1A<Irak1~null><xIrak1> in BMS
    *** reqs: xIrak1 [omission]
    *** source: 11960013-Fig-4b
  *** Eselectin-gene promo-reporter[Luc] is increased irt IL1b (8 hr)
    *** cells: HEK293 in BMS
    *** inhibited by: xIrak1(1-214)"Nterm" [addition]
    *** source: 9430229-Fig-6a

Irak4-act--

  *** Eselectin-gene promo-reporter[Luc] is increased irt IL1b (6 hr)
    *** cells: HEK293<xIL1R1> in BMS
    *** inhibited by: xIrak4(K213A/K214A)"KD" [substitution]
    *** inhibited by: xIrak4(1-191) [substitution]
    *** source: 11960013-Fig-4a

Myd88--

  *** Eselectin-gene promo-reporter[Luc] is increased irt IL1b (8 hr)
    *** cells: HEK293 in BMS
    *** inhibited by: xMyd88(152-296)"Cterm" [substitution]
    *** source: 9430229-Fig-6a
  *** Eselectin-gene promo-reporter[Luc] is increased irt IL1b (8 hr)
    *** cells: HELA in BMS
    *** enhanced by: xMyd88 [addition]
    *** source: 9430229-Fig-2a
  *** Eselectin-gene promo-reporter[Luc] is increased irt IL1b (8 hr)
    *** cells: HELA in BMS
    *** inhibited by: xMyd88(152-296)"Cterm" [addition]
    *** source: 9430229-Fig-2c

not Socs--

  *** Eselectin-gene promo-reporter[Luc] is increased irt IL1 (18 hr)
    *** cells: HEPG2 in BMS
    *** unaffected by: xSocs1 [addition]
    *** source: 10201928-Fig-7

Tbk1--

  *** Eselectin-gene promo-reporter[Luc] is increased irt IL1b (times)
    *** cells: mEFs in BMS
    *** times: 0 2+ 6++ hr
    *** reqs: Tbk1 [KO]
    *** source: 10990461-Fig-6a

Traf6--

  *** Eselectin-gene promo-reporter[Luc] is increased irt IL1b (8 hr)
    *** cells: HEK293 in BMS
    *** inhibited by: xTraf6(mnr)"DN" [addition]
    *** source: 9430229-Fig-6a

=========
No Extras
=========

  *** Eselectin-gene promo-reporter[Luc] is increased itpo (xIL1R1 + xIL1Rap)
    *** cells: HEK293 in BMS
    *** source: 9371760-Fig-1a
  *** Eselectin-gene promo-reporter[Luc] is increased irt IL1b (4 hr)
    *** cells: HEK293<xTLR2><xCd14> in BMS
    *** source: 16982824-Fig-3c
  *** Eselectin-gene promo-reporter[Luc] is increased irt IL1b (4 hr)
    *** cells: HEK293<xTLR2><xTLR1><xCd14> in BMS
    *** source: 16982824-Fig-3c
  *** Eselectin-gene promo-reporter[Luc] is increased irt IL1b (4 hr)
    *** cells: HEK293<xTLR2><xTLR6><xCd14> in BMS
    *** source: 16982824-Fig-3c
  *** Eselectin-gene promo-reporter[Luc] is increased irt IL1 (6 hr)
    *** cells: HEK293<xIL1R1> in BMS
    *** source: 9520446-Fig-6

