============================
Phosphorylation on Tyrosine
============================

  *** Erbb2[Ab]IP Yphos[pYAb] is increased irt Egf (2 min)
    *** cells: MDAMB361 in BMLS
    *** source: 11297548(D)
  *** Erbb2[Ab]IP Yphos[pYAb] is increased irt Egf (5 min)
    *** cells: COS in BMS "quiescent"
    *** source: 10938266(D)
  *** xErbb2[Ab]IP Yphos[pYAb] is increased irt Egf (10 min)
    *** cells: NIH3T3<xEgfR> in BMLS
    *** source: 9710588-Fig-2a
  *** Erbb2[MS] Yphos[pYAb-ppt] is increased irt Egf (times)
    *** cells: HELA in BMLS
    *** times: 0 1+++ 5+++ 10++ 20+ min
    *** source: 15314609(D)

  *** xErbb2[35S] Yphos[pYAb-ppt] is detectable-but unchanged irt Egf (1 hr)
    *** cells: NIH3T3<xErbb2> in BMS
    *** source: 1349015-Fig-4



===============
Coppt with EgfR
===============

  *** xErbb2[35S] copptby[Xlink] xEgfR[35S] is increased irt Egf (1 hr)
    *** cells: NIH3T3<xEgfR><xErbb2> in BMS
    *** partially inhibited by: xEgfR(1-677) [substitution]
    *** partially inhibited by: xEgfR(K721A)"KD" [substitution]
    *** source: 1349015-Fig-2

============
Dimerization
============

  *** xErbb2[Ab]IP oligomerization[Xlink] is unchanged irt Egf (1 hr)
    *** cells: NIH3T3<xErbb2> in BMS
    *** source: 1349015-Fig-2

===============
Kinase Activity
===============

  *** xErbb2[Ab]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: NIH3T3<xErbb2> in BMS
    *** unaffected by: xEgfR [addition]
    *** unaffected by: xEgfR(K721A)"KD" [addition]
    *** unaffected by: xEgfR(1-677) [addition]
    *** source: 1349015-Fig-1b
