  *** xTak1[phosAb] phos(T187/S192)[phosAb] is increased itpo xUbiq
    *** cells: HEK293T<xTak1> in BMS
    *** enhanced by: xTab1 [addition]
    *** enhanced by: xTab2 [addition]
    *** source: 18758450-Fig-S2b
  *** xTak1[phosAb] phos(T187/S192)[phosAb] is increased itpo xUbiq
    *** cells: HEK293T<xTak1> in BMS
    *** inhibited by: xTak1(K63R) [substitution]
    *** source: 18758450-Fig-S2b
  *** xTak1[phosAb] phos(T187/S192)[phosAb] is increased itpo xUbiq
    *** cells: HEK293T<xTak1> in BMS
    *** unaffected by: xTgfbR1(mnr)"CA" [addition]
    *** unaffected by: xTgfbR1(mnr)"KD" [addition]
    *** source: 18758450-Fig-S3b


  *** xTak1[tAb]IP IVKA(Mkk6)(S207)[phosAb] is increased by rUbiq{poly1}
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** comment: xTak1[tAb]IP was shown to contain Tab1 and Tab2
    *** comment: rUbiq was polymerized with (pUbe1 + (rUbc13 + rUev1a) + rTraf6)
    *** source: 19675569-Fig-2f
  *** xTak1[tAb]IP IVKA(Mkk6)(S207)[phosAb] is increased by rUbiq{poly1}
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** comment: xTak1[tAb]IP was shown to contain Tab1 and Tab2
    *** comment: rUbiq was polymerized with (pUbe1 + (rUbc13 + rUev1a) + rTraf6)
    *** comment: unaffected by short linear Ubiq chains [addition]
    *** comment: inhibited by short K63-linked Ubiq chains [addition]
    *** source: 19675569-Fig-S9b
  *** xTak1[tAb]IP IVKA(Mkk6)(S207)[phosAb] is increased by rUbiq{poly1}
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** comment: xTak1[tAb]IP was shown to contain Tab1 and Tab2
    *** comment: rUbiq was polymerized with (pUbe1 + (rUbc13 + rUev1a) + rTraf6)
    *** inhibited by: rCyld [addition]
    *** unaffected by: rCyld(C601S) [addition]
    *** inhibited by: rUsp5 [addition]
    *** source: 19675569-Fig-3a
  *** xTak1[tAb]IP IVKA(Mkk6)(S207)[phosAb] is increased by rUbiq{poly1}
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** comment: xTak1[tAb]IP was shown to contain Tab1 and Tab2
    *** comment: rUbiq was polymerized with (pUbe1 + (rUbc13 + rUev1a) + rTraf6)
    *** source: 19675569-Fig-2e
  *** xTak1[tAb]IP IVKA(Mkk6)(S207)[phosAb] is increased by rUbiq{poly1}
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** comment: xTak1[tAb]IP was shown to contain Tab1 and Tab2
    *** comment: rUbiq was polymerized with (pUbe1 + (rUbc13 + rUev1a) + rTraf6)
    *** source: 19675569-Fig-S10c
  *** xTak1[tAb]IP IVKA(Mkk6)(S207)[phosAb] is increased by rUbiq{poly1}
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** comment: xTak1[tAb]IP was shown to contain Tab1 and Tab2
    *** comment: rUbiq was polymerized with (pUbe1 + (rUbc13 + rUev1a) + rTraf6) followed by inactivation of E1 and E2 with NEM
    *** inhibited by: rUsp5 [addition]
    *** unaffected by: rUsp5(C335A) [addition]
    *** source: 19675569-Fig-S6c
  *** xTak1[tAb]IP IVKA(Mkk6)(S207)[phosAb] is increased by rUbiq{poly1}
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** comment: xTak1[tAb]IP was shown to contain Tab1 and Tab2
    *** comment: rUbiq was polymerized with (pUbe1 + (rUbc13 + rUev1a) + rTraf6) followed by inactivation of E1 and E2 with NEM
    *** source: 19675569-Fig-S6b
  *** xTak1[tAb]IP IVKA(Mkk6)(S207)[phosAb] is increased by rUbiq{poly1}
    *** cells: none
    *** IPfrom: HEK293T<xTab2> in BMS
    *** comment: rUbiq was polymerized with (pUbe1 + (rUbc13 + rUev1a) + rTraf6)
    *** bkg inhibited by: xTak1(T187A)[tAb]IP [substitution]
    *** source: 19675569-Fig-3f
  *** xTak1[tAb]IP IVKA(Mkk6)(S207)[phosAb] is increased by rUbiq{poly1}
    *** cells: none
    *** IPfrom: HEK293T<xTab2> in BMS
    *** comment: rUbiq was polymerized with (pUbe1 + (rUbc13 + rUev1a) + rTraf6)
    *** inhibited by: xTab2(C670A/C673A) [substitution]
    *** source: 19675569-Fig-3e
  *** xTak1[tAb]IP phos(T187)[phosAb] is increased by rUbiq{poly1}
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** comment: xTak1[tAb]IP was shown to contain Tab1 and Tab2
    *** comment: rUbiq was polymerized with (pUbe1 + (rUbc13 + rUev1a) + rTraf6)
    *** unaffected by: xTak1(K63W)[tAb]IP [addition]
    *** inhibited by: xTak1(K63W)[tAb]IP [substitution]
    *** source: 19675569-Fig-3d


  *** xTak1[tAb]IP IVKA(Mkk6)(S207)[phosAb] is increased by (rUbiq + pUbe1 + rUbc13 + rUev1a + rTraf6)
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** comment: xTak1[tAb]IP was shown to contain Tab1 and Tab2
    *** comment: inhibited by removal of rUbiq{poly} before addition to xTak1[tAb]IP
    *** comment: unaffected by removal of (rTraf6 + pUbe1 + rUbc13 + rUev1a) before addition to xTak1[tAb]IP
    *** source: 19675569-Fig-2c
  *** xTak1[tAb]IP IVKA(Mkk6)(S207)[phosAb] is increased by (rUbiq + pUbe1 + rUbc13 + rUev1a + rTraf6)
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** comment: xTak1[tAb]IP was shown to contain Tab1 and Tab2
    *** source: 19675569-Fig-2b
  *** xTak1[tAb]IP phos(T187)[phosAb] is increased by (rUbiq + pUbe1 + rUbc13 + rUev1a + rTraf6)
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** comment: xTak1[tAb]IP was shown to contain Tab1 and Tab2
    *** reqs: rTraf6 [omission]
    *** reqs: rUbc13 and/or rUev1a [omission]
    *** comment: unaffected by addition of NEM to reaction before addition of xTak1[tAb]IP
    *** comment: inhibited by addition of NEM to reaction before addition of (xTak1[tAb]IP + rTraf6)
    *** comment: inhibited by addition of NEM to reaction before addition of (xTak1[tAb]IP + rTraf6 + rUbc13 + rUev1a)
    *** source: 19675569-Fig-2a
  *** xTak1[tAb]IP phos(T187)[phosAb] is increased by (rUbiq + pUbe1 + rUbc13 + rUev1a + rTraf6)
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** comment: xTak1[tAb]IP was shown to contain Tab1 and Tab2
    *** reqs: rTraf6 [omission]
    *** reqs: rUbc13 and/or rUev1a [omission]
    *** reqs: pUbe1 [omission]
    *** source: 19675569-Fig-1b
  *** xTak1[tAb]IP phos(T187)[phosAb] is increased by (rUbiq + pUbe1 + rUbc13 + rUev1a + rTraf6)
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** comment: xTak1[tAb]IP was shown to contain Tab1 and Tab2
    *** reqs: rUbiq [omission]
    *** inhibited by: rUbiq(dig)"K48-only" [substitution]
    *** inhibited by: rUbiq(K63R) [substitution]
    *** inhibited by: rUbiq(dig)"no-lysines" [substitution]
    *** unaffected by: rUbiq(K63only) [substitution]
    *** unaffected by: rUbiq(K48R) [substitution]
    *** source: 19675569-Fig-1b
  *** xTak1[tAb]IP phos(T187)[phosAb] is increased by (rUbiq + pUbe1 + rUbc13 + rUev1a + rTraf6)
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** comment: xTak1[tAb]IP was shown to contain Tab1 and Tab2
    *** source: 19675569-Fig-1c
  *** xTak1[tAb]IP phos[WBMS-PPase] is increased by (rUbiq + pUbe1 + rUbc13 + rUev1a + rTraf6)
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** comment: xTak1[tAb]IP was shown to contain Tab1 and Tab2
    *** source: 19675569-Fig-1c
