=============================
phos(T8/T179/S204/S208/S213)
=============================

  *** rSmad3[32P] phos[32P-ATP] is increased by Cdk4[Ab]IP
    *** cells: none
    *** IPfrom: MV1LU in BMS
    *** partially inhibited by: rSmad3(T179V/S204A/S208A/S213A) [substitution]
    *** partially inhibited by: rSmad3(T8V) [substitution]
    *** inhibited by: rSmad3(T8V/T179V/S204A/S208A/S213A) [substitution]
    *** source: 15241418-Fig-2b

========
phos(T8)
========

  *** rSmad3[phosAb] phos(T8)[phosAb] is increased by Cdk4[Ab]IP
    *** cells: none
    *** IPfrom: MV1LU in BMS
    *** source: 15241418-Fig-S3a
  *** rSmad3[phosAb] phos(T8)[phosAb] is increased by Cdk4[Ab]IP
    *** cells: none
    *** IPfrom: MV1LU in BMS
    *** inhibited by: rSmad3(T8V) [substitution]
    *** source: 15241418-Fig-S3b
  *** Smad3[phosAb] phos(T8)[phosAb] is detectable
    *** cells: mEFs in BMS
    *** partially reqs: Cdk4 [KO]
    *** source: 15241418-Fig-S5c
  *** Smad3[phosAb] phos(T8)[phosAb] is detectable
    *** cells: U2OS in BMS
    *** partially reqs: Cdk4 [RNAi]
    *** source: 15241418-Fig-S5d

==========
phos(T179)
==========

  *** Smad3[phosAb] phos(T179)[phosAb] is detectable
    *** cells: mEFs in BMS
    *** partially reqs: Cdk4 [KO]
    *** source: 15241418-Fig-S5c
  *** rSmad3[phosAb] phos(T179)[phosAb] is increased by Cdk4[Ab]IP
    *** cells: none
    *** IPfrom: MV1LU in BMS
    *** inhibited by: rSmad3(T179V) [substitution]
    *** source: 15241418-Fig-S3b
  *** rSmad3[phosAb] phos(T179)[phosAb] is increased by Cdk4[Ab]IP
    *** cells: none
    *** IPfrom: MV1LU in BMS
    *** source: 15241418-Fig-S3a

==========
phos(S204)
==========

  *** rSmad3[phosAb] phos(S204)[phosAb] is increased by Cdk4[Ab]IP
    *** cells: none
    *** IPfrom: MV1LU in BMS
    *** inhibited by: rSmad3(S204A) [substitution]
    *** source: 15241418-Fig-S3b
  --------- ??? -----------------------------------------
  *** Smad3[phosAb] phos(S204)[phosAb] is detectable
    *** cells: mEFs in BMS
    *** does not req: Cdk4 [KO]
    *** source: 15241418-Fig-S5c
  *** Smad3[phosAb] phos(S204)[phosAb] is detectable
    *** cells: U2OS in BMS
    *** does not req: Cdk4 [RNAi]
    *** source: 15241418-Fig-S5d

==========
phos(S208)
==========

  *** rSmad3[phosAb] phos(S208)[phosAb] is increased by Cdk4[Ab]IP
    *** cells: none
    *** IPfrom: MV1LU in BMS
    *** inhibited by: rSmad3(S208A) [substitution]
    *** source: 15241418-Fig-S3b

==========
phos(S213)
==========

  *** Smad3[phosAb] phos(S213)[phosAb] is detectable
    *** cells: mEFs in BMS
    *** partially reqs: Cdk4 [KO]
    *** source: 15241418-Fig-S5c
  *** rSmad3[phosAb] phos(S213)[phosAb] is increased by Cdk4[Ab]IP
    *** cells: none
    *** IPfrom: MV1LU in BMS
    *** inhibited by: rSmad3(S213A) [substitution]
    *** source: 15241418-Fig-S3b
  *** rSmad3[phosAb] phos(S213)[phosAb] is increased by Cdk4[Ab]IP
    *** cells: none
    *** IPfrom: MV1LU in BMS
    *** source: 15241418-Fig-S3a

==========
total phos
==========

  *** rSmad3[32P] phos[32P-ATP] is increased by (rCdk4{act} + rCyclinD?)
    *** cells: none
    *** comment: recombinant proteins were incubated with HELA extract to activate the Cdk4
    *** source: 15241418-Fig-1b
  *** rSmad3[32P] phos[32P-ATP] is increased by (rCdk4{act} + rCyclinD?)
    *** cells: none
    *** comment: recombinant proteins were incubated with HELA extract to activate the Cdk4
    *** source: 15241418-Fig-S1b
