======================
Direct Phosphorylation
======================

  *** rMdm2[phosAb] phos(Y394)[phosAb] is increased by rAbl1
    *** cells: none
    *** inhibited by: rAbl1(mnr)"KD" [substitution]
    *** source: 12110584-Fig-6e
  *** rMdm2[phosAb] phos(Y394)[phosAb] is increased by rAbl1
    *** cells: none
    *** inhibited by: rMdm2(Y394F) [substitution]
    *** unaffected by: rMdm2(358-493) [substitution]
    *** source: 12110584-Fig-6e
  *** rMdm2[phosAb] phos(Y394)[phosAb] is increased by rAbl1
    *** cells: none
    *** inhibited by: rMdm2(Y394F) [substitution]
    *** unaffected by: rMdm2(S395D) [substitution]
    *** unaffected by: rMdm2(S395A) [substitution]
    *** source: 12110584-Fig-7a

==================================
Phosphorylation in the presence of
==================================

  *** xMdm2[Ab]IP phos(Y394)[phosAb] is increased itpo xAbl1
    *** cells: HEK293<xMdm2> in BMS
    *** inhibited by: xMdm2(Y394F) [substitution]
    *** source: 12110584-Fig-6c
  *** xMdm2[Ab]IP phos(Y394)[phosAb] is increased itpo xAbl1
    *** cells: HEK293<xMdm2> in BMS "treated with Vanadate"
    *** inhibited by: xMdm2(Y394F) [substitution]
    *** unaffected by: xMdm2(S395D) [substitution]
    *** unaffected by: xMdm2(S395A) [substitution]
    *** source: 12110584-Fig-7b
  *** xMdm2[Ab]IP Yphos[pYAb] is increased itpo xAbl1
    *** cells: HEK293<xMdm2> in BMS
    *** inhibited by: xAbl1(mnr)"KD" [substitution]
    *** source: 12110584-Fig-5a
  *** xMdm2[Ab]IP Yphos[pYAb] is increased itpo xAbl1
    *** cells: HEK293<xMdm2> in BMS
    *** unaffected by: xAbl1(mnr)"delSH2" [substitution]
    *** source: 12110584-Fig-5b
  *** xMdm2[Ab]IP Yphos[pYAb] is increased itpo xAbl1
    *** cells: HEK293<xMdm2> in BMS
    *** unaffected by: xMdm2(Y489F) [substitution]
    *** partially inhibited by: xMdm2(Y394F) [substitution]
    *** source: 12110584-Fig-6b

===================
Protein Association
===================

  *** rAbl1[35S] boundby[WB] Mdm2[Ab] is detectable
    *** cells: none
    *** source: 12110584-Fig-1b
  *** rMdm2[Ab] boundby[WB] rAbl1[His] is detectable
    *** cells: none
    *** unaffected by: rMdm2(del(1-50)) [substitution]
    *** unaffected by: rMdm2(del(58-89)) [substitution]
    *** unaffected by: rMdm2(del(90-150)) [substitution]
    *** unaffected by: rMdm2(del(150-230)) [substitution]
    *** unaffected by: rMdm2(del(441-491)) [substitution]
    *** unaffected by: rMdm2(del(222-437)) [substitution]
    *** unaffected by: rMdm2(6-339) [substitution]
    *** unaffected by: rMdm2(1-200) [substitution]
    *** source: 12110584-Fig-2
  *** xMdm2[Ab] copptby[WB] xAbl1[Ab] is detectable
    *** cells: HEK293<xMdm2><xAbl1> in BMS
    *** source: 12110584-Fig-1a

