==========================
SemiDirect Phosphorylation
==========================

  *** rIkk2(K44M)[32P] phos[32P-ATP] is increased by xIkk1[tAb]IP
    *** cells: none
    *** IPfrom: COS in BMS
    *** unaffected by: xIkk1(S176E/S180E)[tAb]IP [substitution]
    *** inhibited by: xIkk1(S176A/S180A)[tAb]IP [substitution]
    *** inhibited by: xIkk1(K44M)[tAb]IP [substitution]
    *** inhibited by: xIkk1(del(560-744)/K44M) [substitution]
    *** source: 10779355-Fig-6a

phos(S177/S181)

  *** rIkk2(K44M)[32P] phos[32P-ATP] is increased by xIkk1[tAb]IP
    *** cells: none
    *** IPfrom: COS in BMS
    *** inhibited by: rIkk2(S177A/S181A) [substitution]
    *** source: 10779355-Fig-6b

===============
Phosphorylation
===============

  *** xIkk2[tAb]IP phos[32Pi] is increased itpo xIkk1
    *** cells: COS in BMS
    *** unaffected by: xIkk1(S176E/S180E) [substitution]
    *** inhibited by: xIkk1(S176A/S180A) [substitution]
    *** inhibited by: xIkk1(K44M) [substitution]
    *** source: 10779355-Fig-3a

==========
Activation
==========

  *** xIkk2[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xIkk1
    *** cells: COS in BMS
    *** enhanced by: xIkk1(S176E/S180E) [substitution]
    *** source: 10779355-Fig-5a

