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Unphosphorylated Cdkn1b is seen mostly in the nucleus in serum-replete cells
============================================================================

  *** Cdkn1b[Ab] infraction(nuclear)[WB] is detectable
    *** cells: WM35 in BMS
    *** source: 18570873-Fig-2a
  *** xCdkn1b[Ab] infraction(nuclear)[WB] is detectable
    *** cells: WM35 in BMS
    *** source: 18570873-Fig-2b
  *** xCdkn1b[XFP] locatedin(nucleus)[IHC] is detectable
    *** cells: WM35<xCdkn1b> in BMS
    *** source: 18570873-Fig-2c

  *** xCdkn1b[XFP] locatedin(nucleus)[IHC] is detectable
    *** cells: WM35<xCdkn1b> in BMS
    *** unaffected by: xCdkn1b(T157A) [substitution]
    *** unaffected by: xCdkn1b(T198A) [substitution]
    *** unaffected by: xCdkn1b(T157A/T198A) [substitution]
    *** comment: xCdkn1b(T157D) also appears in cytoplasm
    *** comment: xCdkn1b(T198D) also appears in cytoplasm
    *** source: 18570873-Fig-2d

  *** rCdkn1b[His] nuc-import[IVnucImport] is detectable
    *** cells: WM35 in BMS "nuclei"
    *** comment: delayed by pretreatment with cytosolic extract from WM35<xMtor>
    *** source: 18570873-Fig-2e

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Phosphorylation of Cdkn1b by Sgk1 causes it to be retained in the cyto
======================================================================

  *** xCdkn1b[XFP] locatedin(cytoplasm)[IHC] is increased itpo xSgk1
    *** cells: WM35<xCdkn1b> in BMS
    *** reversed by: xSgk1(mnr)"KD" [substitution]
    *** source: 18570873-Fig-6e
  *** Cdkn1b[Ab] infraction(nuclear)[WB] is decreased itpo xSgk1
    *** cells: WM35 in BMS
    *** reversed by: xSgk1(mnr)"KD" [substitution]
    *** source: 18570873-Fig-6d

======================================================================
Things that activate Sgk1 cause Cdkn1b to be retained in the cyto
======================================================================

  *** Cdkn1b[Ab] infraction(cytoplasmic)[WB] is increased itpo xMtor
    *** cells: WM35 in BMS
    *** source: 18570873-Fig-2a
  *** Cdkn1b[Ab] infraction(cytoplasmic)[WB] is increased itpo xMtor
    *** cells: WM35 in BMS
    *** source: 18570873-Fig-2b
  *** xCdkn1b[XFP] locatedin(cytoplasm)[IHC] is detectable
    *** cells: WM35<xCdkn1b><xMtor> in BMS
    *** reqs: Rictor [RNAi]
    *** reqs: Raptor [RNAi]
    *** source: 18570873-Fig-7b
  *** xCdkn1b[XFP] locatedin(cytoplasm)[IHC] is increased itpo xMtor
    *** cells: WM35<xCdkn1b> in BMS
    *** inhibited by: xCdkn1b(T157A) [substitution]
    *** inhibited by: xCdkn1b(T198A) [substitution]
    *** inhibited by: xCdkn1b(T157A/T198A) [substitution]
    *** source: 18570873-Fig-2d
  *** xCdkn1b[XFP] locatedin(cytoplasm)[IHC] is increased itpo xMtor
    *** cells: WM35<xCdkn1b> in BMS
    *** source: 18570873-Fig-2c
  *** xCdkn1b[XFP] locatedin(cytoplasm)[IHC] is increased itpo xMtor
    *** cells: WM35<xCdkn1b><xMtor> in BMS
    *** inhibited by: Rapamycin [addition]
    *** source: 18570873-Fig-7d


