===================
Requirement for Src
===================

  *** rCdc42 GDP-dissociation[3H-GDP] is increased by (rArhGef7 + rSrc)
    *** cells: none
    *** reqs: rSrc [omission]
    *** source: 16892055-Fig-3a
  *** xCdc42[tAb] GTP-association[BDPD] is unchanged itpo xArhGef7
    *** cells: COS7<xCdc42> in BMS
    *** source: 9659915-Fig-6b

=============================
Requirement for ArhGef7-Yphos
=============================

  *** rCdc42{GMPPCP}[Ab] snaggedby[WB] xArhGef7[tAb]IP is detectable
    *** cells: NIH3T3<xSrc(mnr)"vSrc"> in BMLS
    *** inhibited by: xArhGef7(Y442F) [substitution]
    *** source: 16892055-Fig-3d

=======================================================
Increase in ArhGef7 activity on Cdc42 itpo xSrc-CA
=======================================================

  *** xArhGef7[tAb]IP IVGefA(Cdc42)[3H-GDP] is increased itpo xSrc(Y527F)"CA"
    *** cells: NIH3T3 in BMLS
    *** inhibited by: xArhGef7(Y619F) [substitution]
    *** source: 16892055-Fig-3b

  *** xArhGef7[Ab] snaggedby[WB] rCdc42{GMPPCP}[GST] is increased by rSrc
    *** cells: NIH3T3<xArhGef7> in BMLS
    *** comment: snagged ArhGef7 is Yphosed
    *** source: 16892055-Fig-3c
  *** ArhGef7[Ab] snaggedby[WB] rCdc42{GMPPCP}[GST] is increased itpo xSrc(Y527F)"CA"
    *** cells: NIH3T3 in BMLS
    *** comment: snagged ArhGef7 is Yphosed
    *** source: 16892055-Fig-3c

  *** xArhGef7[tAb] snaggedby[WB] rCdc42(T17N)[GST] is undetectable
    *** cells: COS7<xArhGef7> in BMLS
    *** source: 15306850-Fig-2b



  *** xCdc42[tAb] copptby[WB] ArhGef7[Ab] is detectable
    *** cells: NIH3T3<xCdc42> in BMLS
    *** enhanced by: xCdc42(F28L)"CA" [substitution]
    *** source: 16892055-Fig-4b

