{
 
"1433x1":{"stype" : "basicOp",
	 "name" : "1433x1",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "sort" : "Protein" }
},
"Cbl":{"stype" : "basicOp",
	 "name" : "Cbl",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "spname" : "CBL_HUMAN", "spnumber" : "P22681", "hugosym" : "CBL", "synonyms" : [ "CBL E3 ubiquitin protein ligase ", "Signal transduction protein CBL ", "Proto-oncogene c-CBL ", "Casitas B-lineage lymphoma proto-oncogene ", "CBL2 " ], "sort" : "Protein" }
},
"Egf":{"stype" : "basicOp",
	 "name" : "Egf",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "category" : "Ligand", "spnumber" : "P01133", "hugosym" : "EGF", "contains" : [ "Epidermal growth factor", "Urogastrone" ], "synonyms" : [ "Pro-epidermal growth factor", "EGF_HUMAN" ], "sort" : "ErbB1L" }
},
"EgfR":{"stype" : "basicOp",
	 "name" : "EgfR",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "category" : "Receptor", "spnumber" : "P00533", "hugosym" : "EGFR", "synonyms" : [ "Epidermal growth factor receptor", "ERBB1", "Receptor tyrosine-protein kinase ErbB-1", "EGFR_HUMAN" ], "sort" : "BProtein" }
},
"ErbB2":{"stype" : "basicOp",
	 "name" : "ErbB2",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "spname" : "ERB2_HUMAN", "spnumber" : "P04626", "hugosym" : "ERBB2", "category" : "Receptor", "synonyms" : [ "Receptor tyrosine-protein kinase erbB-2 precursor", "p185erbB2, C-erbB-2 ", "NEU proto-oncogene ", "Tyrosine kinase-type cell surface receptor HER2 ", "MLN 19, HER2, NEU, NGL, TKR1 " ], "sort" : "BProtein" }
},
"Gab1":{"stype" : "basicOp",
	 "name" : "Gab1",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "spnumber" : "Q13480", "hugosym" : "GAB1", "synonyms" : [ "GRB2-associated binding protein 1", "GRB2-associated binder-1", "GABI_HUMAN" ], "sort" : "GabS" }
},
"Gab2":{"stype" : "basicOp",
	 "name" : "Gab2",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "spnumber" : "Q9UQC2", "hugosym" : "GAB2", "synonyms" : [ "GRB2-associated binding protein 2", "GRB2-associated binder-2", "pp100", "KIAA0571", "GABJ_HUMAN" ], "sort" : "GabS" }
},
"Gabs":{"stype" : "basicOp",
	 "name" : "Gabs",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "category" : "Family", "members" : [ "Gab1", "Gab2" ], "comment" : "", "sort" : "GabS" }
},
"Grb2":{"stype" : "basicOp",
	 "name" : "Grb2",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "spname" : "GRB2_HUMAN", "spnumber" : "P62993", "hugosym" : "GRB2", "synonyms" : [ "Growth factor receptor-bound protein 2", "GRB2 adapter protein ", "SH2/SH3 adapter GRB2 ", "Abundant Src homology protein, Ash protein, Ash " ], "sort" : "BProtein" }
},
"Hras":{"stype" : "basicOp",
	 "name" : "Hras",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "spnumber" : "P01112", "hugosym" : "HRAS", "synonyms" : [ "GTPase HRas", "Transforming protein p21", "v-Ha-ras Harvey rat sarcoma viral oncogene homolog", "Harvey murine sarcoma virus oncogene", "H-Ras-1", "c-H-ras", "HRAS1", "RASH1", "RASH_HUMAN" ], "sort" : "BProtein" }
},
"PP2a":{"stype" : "basicOp",
	 "name" : "PP2a",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "subunits" : [ "Ppp2ca", "Ppp2cb", "Ppp2r1a", "Ppp2r1b", "Ppp2r2a", "Ppp2r2b", "Ppp2r2c", "Ppp2r2d", "Ppp2r3a", "Ppp2r3b", "Ppp2r4", "Ppp2r5a", "Ppp2r5b", "Ppp2r5c", "Ppp2r5d", "Ppp2r5e" ], "comment" : [ "Protein Phosphatase PP2A consists of:  ", "a 36 kDa catalytic subunit: Ppp2ca or Ppp2cb ", "a 65 kDa constant regulatory subunit: Ppp2r1a or Ppp2r1b ", "a variety of regulatory subunits which include: ", "regulatory subunits B: Ppp2r2 - Ppp2r5 ", "viral proteins, and cell signaling molecules. " ], "sort" : "Composite" }
},
"Pak1":{"stype" : "basicOp",
	 "name" : "Pak1",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "spnumber" : "Q13153", "hugosym" : "PAK1", "synonyms" : [ "Serine/threonine-protein kinase PAK 1", "p21-activated kinase 1 ", "PAK-1, P65-PAK, Alpha-PAK ", "PAK1_HUMAN " ], "sort" : "BProtein" }
},
"Pi3k":{"stype" : "basicOp",
	 "name" : "Pi3k",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "subunits" : [ "Pik3ca", "Pik3cb", "Pik3r1" ], "comment" : "PI3 Kinase is a heterodimer of: a p110 catalytic subunit: Pik3ca, Pik3cb, Pik3cd or Pik3cg; and a p85 regulatory subunit: Pik3r1, Pik3r2, or Pik3r3 ", "sort" : "Composite" }
},
"Pik3ca":{"stype" : "basicOp",
	 "name" : "Pik3ca",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "subunitof" : "Pi3k", "spnumber" : "P42336", "hugosym" : "PIK3CA", "synonyms" : [ "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "PI3-kinase p110 subunit alpha", "PtdIns-3-kinase p110", "Pi3k", "PK3CA_HUMAN" ], "sort" : "BProtein" }
},
"Pik3cb":{"stype" : "basicOp",
	 "name" : "Pik3cb",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "subunitof" : "Pi3k", "spnumber" : "P42338", "hugosym" : "PIK3CB", "synonyms" : [ "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "PI3-kinase p110 subunit beta", "PtdIns-3-kinase p110", "Pi3k", "Pi3kbeta", "PK3CA_HUMAN" ], "sort" : "BProtein" }
},
"Pik3r1":{"stype" : "basicOp",
	 "name" : "Pik3r1",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "subunitof" : "Pi3k", "spnumber" : "P27986", "hugosym" : "PIK3R1", "synonyms" : [ "Phosphatidylinositol 3-kinase regulatory alpha subunit", "PI3-kinase p85-alpha subunit", "PtdIns-3-kinase p85-alpha", "Pi3k", "GRB1", "P85A_HUMAN" ], "sort" : "BProtein" }
},
"Plcg":{"stype" : "basicOp",
	 "name" : "Plcg",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "category" : "Family", "members" : [ "Plcg1", "Plcg2" ], "sort" : "Plc" }
},
"Plcg1":{"stype" : "basicOp",
	 "name" : "Plcg1",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "spname" : "PIG1_HUMAN", "spnumber" : "P19174", "hugosym" : "PLCG1", "synonyms" : [ "1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1", "EC 3.1.4.11 ", "Phosphoinositide phospholipase C ", "PLC-gamma-1 ", "Phospholipase C-gamma-1 ", "PLC-II,  PLC-148, PLC1 " ], "sort" : "BProtein" }
},
"Plcg2":{"stype" : "basicOp",
	 "name" : "Plcg2",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "spname" : "PIG2_HUMAN", "spnumber" : "P16885", "hugosym" : "PLCG2", "synonyms" : [ "1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2", "EC 3.1.4.11 ", "Phosphoinositide phospholipase C ", "PLC-gamma-2 ", "Phospholipase C-gamma-2 ", "PLC-IV " ], "sort" : "BProtein" }
},
"Ppp2ca":{"stype" : "basicOp",
	 "name" : "Ppp2ca",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "subunitof" : "PP2a", "spnumber" : "P67775", "hugosym" : "PPP2CA", "synonyms" : [ "Serine/threonine protein phosphatase 2A,", "catalytic subunit, alpha isoform", "PP2A-alpha", "Replication protein C, RP-C", "P2AA_HUMAN " ], "sort" : "Ppp2cS" }
},
"Ppp2cb":{"stype" : "basicOp",
	 "name" : "Ppp2cb",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "subunitof" : "PP2a", "spnumber" : "P62714", "hugosym" : "PPP2CB", "synonyms" : [ "Serine/threonine protein phosphatase 2A,", "catalytic subunit, beta isoform", "PP2A-beta", "P2AB_HUMAN " ], "sort" : "Ppp2cS" }
},
"Ppp2cs":{"stype" : "basicOp",
	 "name" : "Ppp2cs",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "category" : "Family", "members" : [ "Ppp2ca", "Ppp2cb" ], "sort" : "Ppp2cS" }
},
"Ppp2r1a":{"stype" : "basicOp",
	 "name" : "Ppp2r1a",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "subunitof" : "PP2a", "spnumber" : "P30153", "hugosym" : "PPP2R1A", "synonyms" : [ "Serine/threonine protein phosphatase 2A,", "65 kDa regulatory subunit A, alpha isoform", "PP2A, subunit A, PR65-alpha isoform", "PP2A, subunit A, R1-alpha isoform", "2AAA_HUMAN " ], "sort" : "Ppp2r1S" }
},
"Ppp2r1b":{"stype" : "basicOp",
	 "name" : "Ppp2r1b",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "subunitof" : "PP2a", "spnumber" : "P30154", "hugosym" : "PPP2R1B", "synonyms" : [ "Serine/threonine protein phosphatase 2A,", "65 kDa regulatory subunit A, beta isoform", "PP2A, subunit A, PR65-beta isoform", "PP2A, subunit A, R1-beta isoform", "PP2A, structural/regulatory subunit A, beta", "2AAB_HUMAN " ], "sort" : "Ppp2r1S" }
},
"Ppp2r1s":{"stype" : "basicOp",
	 "name" : "Ppp2r1s",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "category" : "Family", "members" : [ "Ppp2r1a", "Ppp2r1b" ], "sort" : "Ppp2r1S" }
},
"Ppp2r2a":{"stype" : "basicOp",
	 "name" : "Ppp2r2a",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "subunitof" : "PP2a", "spnumber" : "P63151", "hugosym" : "PPP2R2A", "synonyms" : [ "Serine/threonine protein phosphatase 2A,", "55 kDa regulatory subunit B,alpha isoform", "PP2A, subunit B, B-alpha isoform", "PP2A, subunit B, B55-alpha isoform", "PP2A, subunit B, PR55-alpha isoform", "PP2A, subunit B, R2-alpha isoform", "Sur-6", "2ABA_HUMAN " ], "sort" : "BProtein" }
},
"Ppp2r2b":{"stype" : "basicOp",
	 "name" : "Ppp2r2b",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "subunitof" : "PP2a", "spnumber" : "Q00005", "hugosym" : "PPP2R2B", "synonyms" : [ "Serine/threonine protein phosphatase 2A,", "55 kDa regulatory subunit B, beta isoform", "PP2A, subunit B, B-beta isoform", "PP2A, subunit B, B55-beta isoform", "PP2A, subunit B, PR55-beta isoform", "PP2A, subunit B, R2-beta isoform", "2ABB_HUMAN " ], "sort" : "BProtein" }
},
"Ppp2r2c":{"stype" : "basicOp",
	 "name" : "Ppp2r2c",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "subunitof" : "PP2a", "spnumber" : "Q9Y2T4", "hugosym" : "PPP2R2C", "synonyms" : [ "Serine/threonine protein phosphatase 2A,", "55 kDa regulatory subunit B, gamma isoform", "PP2A, subunit B, B-gamma isoform", "PP2A, subunit B, B55-gamma isoform", "PP2A, subunit B, PR55-gamma isoform", "PP2A, subunit B, R2-gamma isoform", "IMYPNO1", "2ABG_HUMAN " ], "sort" : "BProtein" }
},
"Ppp2r2d":{"stype" : "basicOp",
	 "name" : "Ppp2r2d",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "subunitof" : "PP2a", "spnumber" : "Q66LE6", "hugosym" : "PPP2R2D", "synonyms" : [ "KIAA1541;", "Serine/threonine-protein phosphatase 2A,", "55 kDa regulatory subunit B, delta isoform", "PP2A, subunit B, B-delta isoform", "PP2A, subunit B, B55-delta isoform", "PP2A, subunit B, PR55-delta isoform", "PP2A, subunit B, R2-delta isoform", "2ABD_HUMAN " ], "sort" : "BProtein" }
},
"Ppp2r3a":{"stype" : "basicOp",
	 "name" : "Ppp2r3a",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "subunitof" : "PP2a", "spnumber" : "Q06190", "hugosym" : "PPP2R3A", "synonyms" : [ "Serine/threonine protein phosphatase 2A,", "72/130 kDa regulatory subunit B", "PP2A, subunit B, B''-PR72/PR130", "PP2A, subunit B, B72/B130 isoforms", "PP2A, subunit B, PR72/PR130 isoforms", "PP2A, subunit B, R3 isoform", "PPP2R3", "2ACA_HUMAN " ], "sort" : "BProtein" }
},
"Ppp2r3b":{"stype" : "basicOp",
	 "name" : "Ppp2r3b",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "subunitof" : "PP2a", "spnumber" : "Q9Y5P8", "hugosym" : "PPP2R3B", "synonyms" : [ "Protein phosphatase 2A, regulatory subunit B'', beta", "Serine/threonine protein phosphatase 2A,", "48 kDa regulatory subunit B", "PP2A, subunit B, PR48 isoform", "PPP2R3L, PPP2R3LY", "2ACC_HUMAN " ], "sort" : "BProtein" }
},
"Ppp2r4":{"stype" : "basicOp",
	 "name" : "Ppp2r4",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "subunitof" : "PP2a", "spnumber" : "Q15257", "hugosym" : "PPP2R4", "synonyms" : [ "Protein phosphatase 2A, regulatory subunit B'", "PP2A, subunit B', PR53 isoform", "Phosphotyrosyl phosphatase activator, PTPA", "PTPA_HUMAN " ], "sort" : "BProtein" }
},
"Ppp2r5a":{"stype" : "basicOp",
	 "name" : "Ppp2r5a",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "subunitof" : "PP2a", "spnumber" : "Q15172", "hugosym" : "PPP2R5A", "synonyms" : [ "Serine/threonine protein phosphatase 2A,", "56 kDa regulatory subunit, alpha isoform", "PP2A, B subunit, B' alpha isoform", "PP2A, B subunit, B56 alpha isoform", "PP2A, B subunit, PR61 alpha isoform", "PP2A, B subunit, R5 alpha isoform", "2A5A_HUMAN " ], "sort" : "BProtein" }
},
"Ppp2r5b":{"stype" : "basicOp",
	 "name" : "Ppp2r5b",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "subunitof" : "PP2a", "spnumber" : "Q15173", "hugosym" : "PPP2R5B", "synonyms" : [ "Serine/threonine protein phosphatase 2A,", "56 kDa regulatory subunit, beta isoform", "PP2A, B subunit, B' beta isoform", "PP2A, B subunit, B56 beta isoform", "PP2A, B subunit, PR61 beta isoform", "PP2A, B subunit, R5 beta isoform", "2A5B_HUMAN " ], "sort" : "BProtein" }
},
"Ppp2r5c":{"stype" : "basicOp",
	 "name" : "Ppp2r5c",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "subunitof" : "PP2a", "spnumber" : "Q13362", "hugosym" : "PPP2R5C", "synonyms" : [ "Serine/threonine protein phosphatase 2A,", "56 kDa regulatory subunit, gamma isoform", "PP2A, B subunit, B' gamma isoform", "PP2A, B subunit, B56 gamma isoform", "PP2A, B subunit, PR61 gamma isoform", "PP2A, B subunit, R5 gamma isoform", "KIAA0044", "2A5G_HUMAN " ], "sort" : "BProtein" }
},
"Ppp2r5d":{"stype" : "basicOp",
	 "name" : "Ppp2r5d",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "subunitof" : "PP2a", "spnumber" : "Q14738", "hugosym" : "PPP2R5D", "synonyms" : [ "Serine/threonine protein phosphatase 2A,", "56 kDa regulatory subunit, delta isoform", "PP2A, B subunit, B' delta isoform", "PP2A, B subunit, B56 delta isoform", "PP2A, B subunit, PR61 delta isoform", "PP2A, B subunit, R5 delta isoform", "2A5D_HUMAN " ], "sort" : "BProtein" }
},
"Ppp2r5e":{"stype" : "basicOp",
	 "name" : "Ppp2r5e",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "subunitof" : "PP2a", "spnumber" : "Q16537", "hugosym" : "PPP2R5E", "synonyms" : [ "Serine/threonine protein phosphatase 2A,", "56 kDa regulatory subunit, epsilon isoform", "PP2A, B subunit, B' epsilon isoform", "PP2A, B subunit, B56 epsilon isoform", "PP2A, B subunit, PR61 epsilon isoform", "PP2A, B subunit, R5 epsilon isoform", "2A5E_HUMAN " ], "sort" : "BProtein" }
},
"Raf1":{"stype" : "basicOp",
	 "name" : "Raf1",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "spnumber" : "P04049", "hugosym" : "RAF1", "synonyms" : [ "RAF proto-oncogene serine/threonine-protein kinase ", "Transforming replication defective murine retrovirus 3611-MSV ", "Raf-1, C-RAF, cRaf, RAF, Oncogene MIL ", "RAF1_HUMAN " ], "sort" : "BProtein" }
},
"Shc":{"stype" : "basicOp",
	 "name" : "Shc",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "spname" : "SHC1_HUMAN", "spnumber" : "P29353", "hugosym" : "SHC1", "synonyms" : [ "SHC transforming protein 1 ", "SH2 domain protein C1 ", "Src homology 2 domain containing transforming protein C1 ", "SHC, SHCA " ], "sort" : "BProtein" }
},
"Sos1":{"stype" : "basicOp",
	 "name" : "Sos1",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "category" : "Guanine Nucleotide Exchange Factor", "spnumber" : "Q07889", "hugosym" : "SOS1", "synonyms" : [ "Son of sevenless protein homolog 1", "SOS-1", "SOS1 guanine nucleotide exchange factor", "Son of sevenless, drosophila homolog 1 ", "SOS1_HUMAN" ], "sort" : "BProtein" }
},
"Src":{"stype" : "basicOp",
	 "name" : "Src",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "spname" : "SRC_HUMAN", "spnumber" : "P12931", "hugosym" : "SRC", "synonyms" : [ "Proto-oncogene tyrosine-protein kinase Src ", "Avian sarcoma virus protein, ASV ", "Tyrosine kinase pp60c-src ", "Tyrosine protein kinase SRC-1 ", "Protooncogene SRC, Rous sarcoma ", "v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog ", "p60-Src, c-Src, SRC1 " ], "sort" : "BProtein" }
},
"Tgfa":{"stype" : "basicOp",
	 "name" : "Tgfa",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "spnumber" : "P01135", "hugosym" : "TGFA", "synonyms" : [ "Transforming growth factor alpha precursor ", "TGF-alpha ", "EGF-like TGF, ETGF ", "TGF type 1  ", "TGFA_HUMAN " ], "sort" : "ErbB1L" }
},
"Ube2l3":{"stype" : "basicOp",
	 "name" : "Ube2l3",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "spname" : "UB2L3_HUMAN", "spnumber" : "P68036", "hugosym" : "UBE2L3", "synonyms" : [ "Ubiquitin-conjugating enzyme E2 L3 (EC 6.3.2.19) ", "Ubiquitin-protein ligase L3 ", "Ubiquitin carrier protein L3 ", "UbcH7, E2-F1, L-UBC, UBCE7, UBCH7 " ], "sort" : "BProtein" }
},
"Vav2":{"stype" : "basicOp",
	 "name" : "Vav2",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "spname" : "VAV2_HUMAN", "spnumber" : "P52735", "hugosym" : "VAV2", "synonyms" : "Vav-2 protein.", "sort" : "BProtein" }
},

"DAG":{"stype" : "basicOp",
	 "name" : "DAG",
	 "modname" : "CHEMICALOPS",
	 "metadata" : { "category" : "Chemical", "keggcpd" : "C00165", "synonyms" : "Diacylglycerol ", "sort" : "Chemical" }
},
"IP3":{"stype" : "basicOp",
	 "name" : "IP3",
	 "modname" : "CHEMICALOPS",
	 "metadata" : { "category" : "Chemical", "keggcpd" : "C04569", "synonyms" : "Inositol-1,4,5-triphosphate ", "sort" : "Chemical" }
},
"PIP2":{"stype" : "basicOp",
	 "name" : "PIP2",
	 "modname" : "CHEMICALOPS",
	 "metadata" : { "category" : "Chemical", "keggcpd" : "C04569", "synonyms" : "Phosphatidylinositol-4,5P ", "sort" : "Chemical" }
},
"PIP3":{"stype" : "basicOp",
	 "name" : "PIP3",
	 "modname" : "CHEMICALOPS",
	 "metadata" : { "category" : "Chemical", "keggcpd" : "C05981", "synonyms" : "Phosphatidylinositol-3,4,5P ", "sort" : "Chemical" }
},
"cAMP":{"stype" : "basicOp",
	 "name" : "cAMP",
	 "modname" : "CHEMICALOPS",
	 "metadata" : { "sort" : "Chemical" }
},
 
} 
