*** Akt1--
  *** Akt1[phosAb] phos(S473)[phosAb] is increased irt Cd40L (20 min)
    *** cells: mEFs<Traf2~null><xTraf2> in BMS
    *** reqs: xTraf2 [omission]
    *** source: 16260598-Fig-5d
  *** Akt1[phosAb] phos(S473)[phosAb] is increased irt Cd40L (20 min)
    *** cells: mEFs<Traf6~null><xTraf6> in BMS
    *** reqs: xTraf6 [omission]
    *** source: 16260598-Fig-7b
  *** Akt1[phosAb] phos(S473)[phosAb] is increased irt Cd40L (times)
    *** cells: mBMDCs in BMLS
    *** times: 0 5 20+ 60+ 180++ min
    *** comment: reqs Cblb[KO] for increase at 20 min only
    *** source: 11406619-Fig-4b
  *** Akt1[phosAb] phos(S473)[phosAb] is increased irt Cd40L (times)
    *** cells: mEFs in BMS
    *** times: 0 20++ 30+ min
    *** bkg reqs: Traf2 [KO]
    *** source: 16260598-Fig-4c
  *** Akt1[phosAb] phos(S473)[phosAb] is increased irt Cd40L (times)
    *** cells: mSpLs in BMLS
    *** times: 0 5+ 20+ min
    *** partially reqs: Cbl [KO]
    *** source: 11406619-Fig-4c
  *** Akt1[phosAb] phos(S473)[phosAb] is increased irt Cd40L (times)
    *** cells: mSpLs in BMLS
    *** times: 0 5+ 20+ min
    *** partially reqs: Cblb [KO]
    *** source: 11406619-Fig-4c
*** Bcl6--
  *** Bcl6-gene mRNA[Northern] is decreased irt anti-Cd40 (24 hr)
    *** cells: RAMOS in BMS
    *** unaffected by: IL4 [cotreatment]
    *** source: 10601358-Fig-4a
  *** Bclxl-gene mRNA[RTPCR] is increased irt anti-Cd40 (2 hr)
    *** cells: mSpCs<Cd40~null><xCd40> in BMS
    *** unaffected by: xCd40(del(230-247))"dTR6" [substitution]
    *** unaffected by: xCd40(T255A)"dTR23" [substitution]
    *** partially inhibited by: xCd40(del(230-247)/T255A)"dTRs" [substitution]
    *** source: 12354380-Fig-7c
  *** Bclxl-gene mRNA[RTPCR] is increased irt anti-Cd40 (2 hr)
    *** cells: mSpCs<Cd40~pos> in BMS
    *** source: 12354380-Fig-7c
  *** Cbl[Ab] copptby[WB] Cd40[Ab] is increased irt Cd40L (times)
    *** cells: mBMDCs in BMS
    *** times: 0+ 5++ 10+++ min
    *** source: 11406619-Fig-1b
  *** Cbl[Ab]IP Yphos[pYAb] is decreased irt PP1 (90 min)
    *** cells: mBMDCs in BMS
    *** source: 11406619-Fig-1d
  *** CcL2-gene mRNA[Northern] is increased irt Cd40L (6 hr)
    *** cells: hUVECs in BMS
    *** bkg inhibited by: Curcumin [pretreatment]
    *** bkg inhibited by: NDGA [pretreatment]
    *** source: 11714736-Fig-4a
  *** CcL2-gene mRNA[Northern] is increased irt Cd40L (6 hr)
    *** cells: hUVECs in BMS
    *** inhibited by: xTraf3 [addition]
    *** source: 11714736-Fig-3a
  *** CcL2-gene mRNA[Northern] is increased irt Cd40L (6 hr)
    *** cells: hUVECs in BMS
    *** unaffected by: Curcumin [pretreatment]
    *** source: 11714736-Fig-4c
  *** CcL5-gene promo-reporter[Luc] is increased irt Cd40L (18 hr)
    *** cells: 9HTEO in BMS
    *** inhibited by: xIkk1(K44A)"DN" [addition]
    *** inhibited by: xIkk2(K44A)"DN" [addition]
    *** source: 12122011-Fig-5a
  *** CcL5-gene promo-reporter[Luc] is increased irt Cd40L (18 hr)
    *** cells: 9HTEO in BMS
    *** inhibited by: xTraf2 [addition]
    *** inhibited by: xTraf2(mnr)"DN" [addition]
    *** source: 12122011-Fig-9
  *** CcL5-gene promo-reporter[Luc] is increased irt Cd40L (18 hr)
    *** cells: 9HTEO<xTraf3> in BMS
    *** inhibited by: xTraf3(mnr)"DN" [substitution]
    *** source: 12122011-Fig-9
  *** CcL5-gene promo-reporter[Luc] is increased irt Cd40L (18 hr)
    *** cells: 9HTEO<xTraf3> in BMS
    *** source: 12122011-Fig-10
  *** CcL5[Ab] secretion[ELISA] is increased irt Cd40L (tnr)
    *** cells: 9HTEO in BMS
    *** source: 12122011-Fig-5b
  *** CcL5[Ab] secretion[ELISA] is increased irt Cd40L (tnr)
    *** cells: HT29<xCd40> in BMS
    *** reqs: xCd40 [omission]
    *** inhibited by: xCd40(T254A) [substitution]
    *** source: 12122011-Fig-8
  *** Cd40[Ab]IP IVKA(Khdrbs1)[32P-ATP] is increased irt Cd40L (times)
    *** cells: mBMDCs in BMS
    *** times: 0 5 10+ min
    *** source: 11406619-Fig-1b
*** Cd80--
  *** Cd80[Ab] surface-exp[FACS] is increased irt anti-Cd40 (3 days)
    *** cells: A202J in BMS
    *** partially reqs: Traf2 [null-mut]
    *** source: 12958312-Fig-8a
  *** Cd80[Ab] surface-exp[FACS] is increased irt Cd40L (36 hr)
    *** cells: hBCs in BMS
    *** source: 12818164-Fig-4
  *** Cd80[Ab] surface-exp[FACS] is increased irt Cd40L (36 hr)
    *** cells: hPBMCs<Cd40L~null> in BMS
    *** source: 12818164-Fig-4
  *** Cd80[Ab] surface-exp[FACS] is unchanged irt Cd40L (24 hr)
    *** cells: mSpBCs in BMS
    *** unaffected by: kMekk1(1-1188)"del-kinase-domain" [addition]
    *** source: 17143273-Fig-6a
  *** Cd80[Ab] surface-exp[FACS] is unchanged irt Cd40L (36 hr)
    *** cells: hPBMCs<Cd40~null> in BMS
    *** source: 12818164-Fig-4
  *** Cd80[Ab] surface-exp[FACS] is unchanged irt Cd40L (36 hr)
    *** cells: hPBMCs<Nemo~null> in BMS
    *** source: 12818164-Fig-4
*** Cd86--
  *** Cd86[Ab] surface-exp[FACS] is increased irt anti-Cd40 (24 hr)
    *** cells: mSpBCs in BMLS
    *** does not req: Peli1 [KO]
    *** source: 19734906-Fig-3a
  *** Cd86[Ab] surface-exp[FACS] is increased irt Cd40L (18 hr)
    *** cells: mBMDCs in BMS
    *** does not req: Traf1 [KO]
    *** source: 12370254-Fig-4a
  *** Cd86[Ab] surface-exp[FACS] is increased irt Cd40L (18 hr)
    *** cells: mSpCs<Cd40~null><xCd40> in BMS
    *** partially inhibited by: xCd40(del(230-247))"dTR6" [substitution]
    *** partially inhibited by: xCd40(T255A)"dTR23" [substitution]
    *** inhibited by: xCd40(del(230-247)/T255A)"dTRs" [substitution]
    *** source: 12354380-Fig-6
  *** Cd86[Ab] surface-exp[FACS] is increased irt Cd40L (18 hr)
    *** cells: mSpCs<Cd40~pos> in BMS
    *** source: 12354380-Fig-6
  *** Ciap2-gene promo-reporter[Luc] is increased irt Cd40L (36 hr)
    *** cells: mEFs in BMS
    *** does not req: Tpl2 [KO]
    *** source: 15670770-Fig-1f
  *** Ciap2-gene promo-reporter[Luc] is increased itpo xCd40
    *** cells: HEK293 in BMS
    *** inhibited by: xTpl2(K167M) [addition]
    *** source: 15670770-Fig-1b
  *** Ciap2[Ab]IP ubiq[K63UbAb] is increased irt anti-Cd40 (1 hr)
    *** cells: A20 in BMS
    *** does not req: Traf3 [RNAi]
    *** source: 18997792-Fig-6d
  *** Ciap2[Ab]IP ubiq[K63UbAb] is increased irt anti-Cd40 (1 hr)
    *** cells: A20 in BMS
    *** reqs: Traf2 [RNAi]
    *** source: 18997792-Fig-6d
  *** xCiap2[tAb]IP ubiq[K63UbAb] is increased irt anti-Cd40 (1 hr)
    *** cells: HEK293T<xCiap2> in BMS
    *** source: 18997792-Fig-6e
  *** xCiap2[tAb]IP ubiq[K63UbAb] is increased irt anti-Cd40 (1 hr)
    *** cells: HEK293T<xCiap2><xTraf2> in BMS
    *** source: 18997792-Fig-6e
*** CyclinD1--
  *** CyclinD1-gene mRNA[RTPCR] is unchanged irt Cd40L (24 hr)
    *** cells: mSpBCs in BMS
    *** unaffected by: kMekk1(1-1188)"del-kinase-domain" [addition]
    *** source: 17143273-Fig-5b
  *** CyclinD1[Ab] prot-exp[WB] is unchanged irt Cd40L (24 hr)
    *** cells: mSpBCs in BMS
    *** unaffected by: kMekk1(1-1188)"del-kinase-domain" [addition]
    *** source: 17143273-Fig-5c
*** CyclinD2--
  *** CyclinD2-gene mRNA[RTPCR] is increased irt Cd40L (24 hr)
    *** cells: mSpBCs in BMS
    *** inhibited by: kMekk1(1-1188)"del-kinase-domain" [addition]
    *** source: 17143273-Fig-5b
  *** CyclinD2[Ab] prot-exp[WB] is increased irt Cd40L (24 hr)
    *** cells: mSpBCs in BMS
    *** partially inhibited by: kMekk1(1-1188)"del-kinase-domain" [addition]
    *** source: 17143273-Fig-5c
*** CyclinD3--
  *** CyclinD3-gene mRNA[RTPCR] is unchanged irt Cd40L (24 hr)
    *** cells: mSpBCs in BMS
    *** unaffected by: kMekk1(1-1188)"del-kinase-domain" [addition]
    *** source: 17143273-Fig-5b
  *** CyclinD3[Ab] prot-exp[WB] is unchanged irt Cd40L (24 hr)
    *** cells: mSpBCs in BMS
    *** unaffected by: kMekk1(1-1188)"del-kinase-domain" [addition]
    *** source: 17143273-Fig-5c
  *** Dgka-gene mRNA[RTPCR] is decreased irt anti-Cd40 (2 hr)
    *** cells: mSpCs<Cd40~null><xCd40> in BMS
    *** unaffected by: xCd40(del(230-247))"dTR6" [substitution]
    *** source: 12354380-Fig-7c
  *** Dgka-gene mRNA[RTPCR] is decreased irt anti-Cd40 (2 hr)
    *** cells: mSpCs<Cd40~pos> in BMS
    *** source: 12354380-Fig-7c
*** Erks--
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt anti-Cd40 (times)
    *** cells: mSpBCs in BMS
    *** times: 0 5+++ 10++ 30+ 60 min
    *** partially inhibited by: kMekk1(1-1188)"del-kinase-domain" [addition]
    *** source: 17143273-Fig-3
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Cd40L (times)
    *** cells: hUVECs in BMS
    *** times: 0+ 10++ 20+ min
    *** unaffected by: xTraf3 [addition]
    *** comment: xTraf3 may prevent decrease in phos at 20 min
    *** source: 11714736-Fig-5b
*** FceR2--
  *** FceR2-gene mRNA[RPA] is increased irt anti-Cd40 (24 hr)
    *** cells: RAMOS in BMS
    *** enhanced by: IL4 [cotreatment]
    *** source: 10601358-Fig-1
  *** FceR2[Ab] surface-exp[FACS] is increased irt Cd40L (18 hr)
    *** cells: mSpCs<Cd40~null><xCd40> in BMS
    *** unaffected by: xCd40(del(230-247))"dTR6" [substitution]
    *** partially inhibited by: xCd40(T255A)"dTR23" [substitution]
    *** inhibited by: xCd40(del(230-247)/T255A)"dTRs" [substitution]
    *** source: 12354380-Fig-6
  *** FceR2[Ab] surface-exp[FACS] is increased irt Cd40L (18 hr)
    *** cells: mSpCs<Cd40~pos> in BMS
    *** source: 12354380-Fig-6
*** Hsp70--
  *** Hsp70[Ab] infraction(P100)[WB] is unchanged irt anti-Cd40 (times)
    *** cells: mSpBCs in BMS
    *** times: 0 10 30 60 min
    *** source: 18635759-Fig-S6
*** Cd54
  *** Cd54[Ab] surface-exp[FACS] is increased irt Cd40L (18 hr)
    *** cells: mSpCs<Cd40~null><xCd40> in BMS
    *** partially inhibited by: xCd40(del(230-247))"dTR6" [substitution]
    *** partially inhibited by: xCd40(T255A)"dTR23" [substitution]
    *** inhibited by: xCd40(del(230-247)/T255A)"dTRs" [substitution]
    *** source: 12354380-Fig-6
  *** Cd54[Ab] surface-exp[FACS] is increased irt Cd40L (18 hr)
    *** cells: mSpCs<Cd40~pos> in BMS
    *** source: 12354380-Fig-6
  *** Cd54[Ab] surface-exp[FACS] is increased irt Cd40L (36 hr)
    *** cells: hBCs in BMS
    *** source: 12818164-Fig-4
  *** Cd54[Ab] surface-exp[FACS] is increased irt Cd40L (36 hr)
    *** cells: hPBMCs<Cd40L~null> in BMS
    *** source: 12818164-Fig-4
  *** Cd54[Ab] surface-exp[FACS] is unchanged irt Cd40L (24 hr)
    *** cells: mSpBCs in BMS
    *** unaffected by: kMekk1(1-1188)"del-kinase-domain" [addition]
    *** source: 17143273-Fig-6a
  *** Cd54[Ab] surface-exp[FACS] is unchanged irt Cd40L (36 hr)
    *** cells: hPBMCs<Cd40~null> in BMS
    *** source: 12818164-Fig-4
  *** Cd54[Ab] surface-exp[FACS] is unchanged irt Cd40L (36 hr)
    *** cells: hPBMCs<Nemo~null> in BMS
    *** source: 12818164-Fig-4
  *** Ikba[Ab] prot-exp[WB] is decreased irt anti-Cd40 (times)
    *** cells: HEK293<xCd40> in BMS
    *** times: 0+ 30 300+ min
    *** source: 12374738-Fig-1d
  *** Ikba[Ab] prot-exp[WB] is decreased irt anti-Cd40 (times)
    *** cells: HEK293<xCd40> in BMS
    *** times: 0++ 10+ 30 min
    *** unaffected by: xNik(del(624-947))"DN" [addition]
    *** source: 12374738-Fig-7b
  *** Ikba[Ab] prot-exp[WB] is decreased irt Cd40L (times)
    *** cells: HEK293<xCd40> in BMS
    *** times: 0+ 30 300+ min
    *** source: 12374738-Fig-1d
  *** Ikba[Ab] prot-exp[WB] is decreased irt Cd40L (times)
    *** cells: mBMDCs in BMLS
    *** times: 0++ 5+ 20+ 60+ 180++ min
    *** unaffected by: Cblb [KO]
    *** source: 11406619-Fig-4b
  *** Ikba[Ab] prot-exp[WB] is decreased irt Cd40L (times)
    *** cells: mSpBCs in BMS
    *** times: 0++ 30 120+ 240+ min
    *** reversed by: MG132 [addition]
    *** source: 12374738-Fig-5b
  *** Ikba[Ab] prot-exp[WB] is unchanged irt Cd40L (times)
    *** cells: hUVECs in BMS
    *** times: 0+ 5+ 15+ 30+ 60+ min
    *** source: 11714736-Fig-4d
  *** Ikba[phosAb] phos(S32)[phosAb] is increased irt Cd40L (times)
    *** cells: 9HTEO in BMS
    *** times: 0 5++ 15+ 30+ min
    *** source: 12122011-Fig-4a
  *** Ikba[phosAb] phos(sitenr)[phosAb] is increased irt anti-Cd40 (times)
    *** cells: A202J in BMS
    *** times: 0 5+ 10+ min
    *** does not req: Traf2 [null-mut]
    *** source: 12958312-Fig-7a
*** Ikk1--
  *** Ikk1[Ab] copptby[WB] Cd40[Ab] is unchanged irt anti-Cd40 (times)
    *** cells: mSpBCs in BMS
    *** times: 0 10 30 min
    *** source: 18635759-Fig-2c
  *** Ikk1[Ab] copptby[WB] Mekk1[Ab] is unchanged irt anti-Cd40 (times)
    *** cells: mSpBCs in BMS
    *** times: 0 10 30 min
    *** source: 18635759-Fig-2d
  *** xIkk1[tAb]IP IVKA(auto)[32P-ATP] is increased itpo xCd40
    *** cells: HEK293 in BMS "treated with anti-Cd40 (15 min)"
    *** inhibited by: xTpl2(K167M) [addition]
    *** source: 15670770-Fig-1a
  *** xIkk1[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xCd40
    *** cells: HEK293 in BMS "treated with anti-Cd40 (15 min)"
    *** inhibited by: xTpl2(K167M) [addition]
    *** source: 15670770-Fig-1a
*** IL6--
  *** IL6[Ab] secretion[ELISA] is increased irt Cd40L (24 hr)
    *** cells: mSpBCs in BMS
    *** bkg inhibited by: kMekk1(1-1188)"del-kinase-domain" [addition]
    *** source: 17143273-Fig-6b
  *** IL8[Ab] secretion[ELISA] is increased irt Cd40L (6 hr)
    *** cells: hUVECs in BMS
    *** inhibited by: xTraf3 [addition]
    *** source: 11714736-Fig-3b
  *** IL12a-gene mRNA[RTPCR] is increased irt Cd40L (times)
    *** cells: hPBMonos in BMS "treated with Csf2 + IL4 for 6 days"
    *** times: 0 1++ 2+ days
    *** source: 11114383-Fig-3b
  *** IL12a-gene mRNA[RTPCR] is increased irt Cd40L (times)
    *** cells: hPBMonos in BMS "treated with Csf2 + IL4 for 6 days"
    *** times: 0+ 1++ 2++ days
    *** source: 11114383-Fig-3b
  *** IL23a-gene mRNA[RTPCR] is detectable-but unchanged irt Cd40L (times)
    *** cells: hPBMonos in BMS "treated with Csf2 + IL4 for 6 days"
    *** times: 0+ 1+ 2+ days
    *** source: 11114383-Fig-3b
  *** Irf1-gene mRNA[Northern] is increased irt anti-Cd40 (times)
    *** cells: BJAB in BMS
    *** times: 0+ 1+++ 3++ 6+ 18+ hr
    *** source: 9133417-Fig-5c
  *** Irf3-gene mRNA[RTPCR] is unchanged irt Cd40L (times)
    *** cells: hPDCs in BMS
    *** times: 0+ 3++ 15+ hr
    *** source: 12707322-Fig-6
  *** Irf4-gene mRNA[Northern] is increased irt anti-Cd40 (24 hr)
    *** cells: RAMOS in BMS
    *** enhanced by: IL4 [cotreatment]
    *** source: 10601358-Fig-4a
  *** Irf4[Ab]IP prot-exp[WB] is unchanged irt anti-Cd40 (24 hr)
    *** cells: hTonsillarBCs in BMS
    *** source: 10601358-Fig-4b
  *** Irf7-gene mRNA[RTPCR] is  unchanged irt Cd40L (times)
    *** cells: hPDCs in BMS
    *** times: 0+ 3+ 15+ hr
    *** source: 12707322-Fig-6
*** Jak3--
*** Jun--
  *** Jun[Ab] prot-exp[WB] is increased irt anti-Cd40 (times)
    *** cells: mSpBCs in BMS
    *** times: 0 24++ 48+ hr
    *** inhibited by: kMekk1(1-1188)"del-kinase-domain" [addition]
    *** comment: Jun is phosed on S63
    *** source: 17143273-Fig-5a
*** Junb--
  *** Junb[Ab] prot-exp[WB] is increased irt anti-Cd40 (times)
    *** cells: mSpBCs in BMS
    *** times: 0 24++ 48+ hr
    *** partially inhibited by: kMekk1(1-1188)"del-kinase-domain" [addition]
    *** source: 17143273-Fig-5a
*** Map4k2--
  *** Map4k2[Ab] copptby[WB] Mekk1[Ab] is unchanged irt anti-Cd40 (times)
    *** cells: mSpBCs in BMS
    *** times: 0 5 10 30 60 min
    *** source: 17143273-Fig-4c
  *** Map4k2[Ab] copptby[WB] Mekk1[Ab] is unchanged irt Cd40L (times)
    *** cells: mSpBCs in BMS
    *** times: 0 5 10 30 60 min
    *** source: 17143273-Fig-S7b
  *** Map4k2[Ab] prot-exp[WB] is unchanged irt anti-Cd40 (times)
    *** cells: mSpBCs in BMS
    *** times: 0+ 5+ 10+ 30+ 60+ min
    *** source: 17143273-Fig-4b
*** Mekk1--
  *** Mekk1[Ab] prot-exp[WB] is unchanged irt anti-Cd40 (times)
    *** cells: mSpBCs in BMS
    *** times: 0+ 5+ 10+ 30+ 60+ min
    *** source: 17143273-Fig-4a
  *** Mekk1[Ab] prot-exp[WB] is unchanged irt anti-Cd40 (times)
    *** cells: mSpBCs in BMS
    *** times: 0+ 5+ 10+ 30+ 60+ min
    *** source: 17143273-Fig-4b
  *** Mekk1[Ab]IP ubiq[UbAb] is increased irt anti-Cd40 (times)
    *** cells: mSpBCs in BMS
    *** times: 0 5 10++ 30+ 60 min
    *** source: 17143273-Fig-S8a
  *** Mekk1[Ab]IP ubiq[UbAb] is increased irt anti-Cd40 (times)
    *** cells: mSpBCs in BMS
    *** times: 0 10++ 30+ 60 min
    *** does not req: Traf3 [KO]
    *** source: 18635759-Fig-S2
  *** Mekk1[Ab]IP ubiq[UbAb] is increased irt anti-Cd40 (times)
    *** cells: mSpBCs in BMS
    *** times: 0 10++ 30+ 60 min
    *** does not req: Traf6 [KO]
    *** source: 18635759-Fig-S2
  *** Mekk1[Ab]IP ubiq[UbAb] is increased irt anti-Cd40 (times)
    *** cells: mSpBCs in BMS
    *** times: 0 10++ 30+ 60 min
    *** reqs: Traf2 [KO]
    *** source: 18635759-Fig-S2
  *** Mekk1[Ab]IP ubiq[UbAb] is increased irt anti-Cd40 (times)
    *** cells: mSpBCs in BMS "S100-fraction"
    *** times: 0 10+ 30+ min
    *** inhibited by: SmacMimetic [addition]
    *** inhibited by: MG132 [addition]
    *** source: 18635759-Fig-S10
*** Mhc2s--
  *** Mhc2s[Ab] surface-exp[FACS] is increased irt anti-Cd40 (24 hr)
    *** cells: mSpBCs in BMLS
    *** does not req: Peli1 [KO]
    *** source: 19734906-Fig-3a
  *** Mhc2s[Ab] surface-exp[FACS] is increased irt Cd40L (24 hr)
    *** cells: mSpBCs in BMS
    *** unaffected by: kMekk1(1-1188)"del-kinase-domain" [addition]
    *** source: 17143273-Fig-6a
*** Mkk4--
  *** Mkk4[Ab]IP IVKA(Jnk1,Jun)[32P-ATP] is increased irt anti-Cd40 (15 min)
    *** cells: WEHI231 in BMS
    *** source: 9535930-Fig-5d
  *** Mkk7[Ab]IP IVKA(Jnk1,Jun)[32P-ATP] is increased irt anti-Cd40 (15 min)
    *** cells: WEHI231 in BMS
    *** source: 9535930-Fig-5d
*** Mkk36s--
  *** Mkk36s[phosAb] phos(SVAKT)[phosAb] is increased irt anti-Cd40 (times)
    *** cells: mSpBCs in BMS
    *** times: 0 10+ 30+ min
    *** inhibited by: SmacMimetic [addition]
    *** source: 18635759-Fig-6a
*** Nemo--
  *** Nemo[Ab]IP IVKA(Ikba)[32P-ATP] is increased irt Cd40L (times)
    *** cells: RS11846 in BMS
    *** times: 0 5+ 10+ 20+ min
    *** source: 15670770-Fig-2a
*** Nfkb--
  *** Nfkb-reporter[Luc] is increased irt Cd40L (5 hr)
    *** cells: HEK293T in BMS
    *** source: 12917689-Fig-2c
  *** Nfkb-reporter[Luc] is increased irt Cd40L (8 hr)
    *** cells: mEFs in BMS
    *** partially inhibited by: xCd40(T254A)"mT2/T3" [addition]
    *** partially inhibited by: xCd40(Q234A/E235A)"mT6" [addition]
    *** source: 16260598-Fig-6b
  *** Nfkb-reporter[Luc] is increased irt Cd40L (8 hr)
    *** cells: mEFs in BMS
    *** partially reqs: Traf2 [KO]
    *** source: 16260598-Fig-6b
  *** Nfkb-reporter[Luc] is increased irt Cd40L (8 hr)
    *** cells: mEFs<Traf2~null> in BMS
    *** inhibited by: xTraf6(mnr)"DN" [addition]
    *** source: 16260598-Fig-6a
  *** Nfkb-reporter[Luc] is increased irt Cd40L (8 hr)
    *** cells: mEFs<Traf2~null> in BMS
    *** unaffected by: xTraf3(mnr)"DN" [addition]
    *** source: 16260598-Fig-6a
  *** Nfkb-reporter[Luc] is increased irt Cd40L (36 hr)
    *** cells: mEFs in BMS
    *** bkg reqs: Tpl2 [KO]
    *** source: 15670770-Fig-1f
  *** Nfkb-reporter[Luc] is increased itpo xCd40
    *** cells: HEK293 in BMS
    *** inhibited by: xTpl2(K167M) [addition]
    *** source: 15670770-Fig-1b
  *** Nfkb[RE] oligo-binding[EMSA] is increased irt anti-Cd40 (times)
    *** cells: HEK293<xCd40> in BMS
    *** times: 0 30++ 60+ 180+ 360+ 960+ min
    *** source: 12374738-Fig-4b
  *** Nfkb[RE] oligo-binding[EMSA] is increased irt anti-Cd40 (times)
    *** cells: mSpBCs in BMS
    *** times: 0 30+ 60+ 120+ hr
    *** reqs: Traf6 [KO]
    *** source: 10215628-Fig-5b
  *** Nfkb[RE] oligo-binding[EMSA] is increased irt Cd40L (5 hr)
    *** cells: mSpBCs in BMS
    *** source: 12374738-Fig-5c
  *** Nfkb[RE] oligo-binding[EMSA] is increased irt Cd40L (30 min)
    *** cells: HELA<xCd40> in BMS "nuclear-extracts"
    *** partially inhibited by: xCd40(T254A)"mT2/T3" [substitution]
    *** partially inhibited by: xCd40(Q234A/E235A)"mT6" [substitution]
    *** inhibited by: xCd40(Q234A/E235A/Q263A/T254A)"mT2/T3/T6" [substitution]
    *** partially inhibited by: xCd40(Q234A/E235A/Q263A)"mT3/T6" [substitution]
    *** source: 16260598-Fig-2c
  *** Nfkb[RE] oligo-binding[EMSA] is increased irt Cd40L (30 min)
    *** cells: mEFs<Traf2~null><xTraf2> in BMS
    *** partially reqs: xTraf2 [omission]
    *** source: 16260598-Fig-5b
  *** Nfkb[RE] oligo-binding[EMSA] is increased irt Cd40L (times)
    *** cells: mEFs in BMS
    *** times: 0 30++ 60+ 180+ min
    *** partially reqs: Traf2 [KO]
    *** source: 16260598-Fig-4e
  *** Nfkb[RE] oligo-binding[EMSA] is increased irt Cd40L (times)
    *** cells: mEFs in BMS
    *** times: 0 30++ 60+ min
    *** bkg reqs: Traf6 [KO]
    *** source: 16260598-Fig-6d
*** Nfkb1--
*** Nfkb2--
  *** Nfkb2[Ab] cleavage[WB] is increased irt anti-Cd40 (12 hr)
    *** cells: HEK293<xCd40> in BMS
    *** source: 12374738-Fig-1a
  *** Nfkb2[Ab] cleavage[WB] is increased irt anti-Cd40 (times)
    *** cells: HEK293<xCd40> in BMS
    *** times: 0 1+ 2++ 4++ 6+++ hr
    *** unaffected by: xIkba(mnr)"blocks-Nfkb-activation" [addition]
    *** source: 12374738-Fig-2a
  *** Nfkb2[Ab] cleavage[WB] is increased irt anti-Cd40 (times)
    *** cells: HEK293<xCd40> in BMS
    *** times: 0 3+ 6++ 9++ 24+++ hr
    *** source: 12374738-Fig-1c
  *** Nfkb2[Ab] cleavage[WB] is increased irt anti-Cd40 (times)
    *** cells: HEK293<xCd40> in BMS
    *** times: 0 30 180+ 360++ min
    *** inhibited by: xNik(del(624-947))"DN" [addition]
    *** source: 12374738-Fig-7a
  *** Nfkb2[Ab] cleavage[WB] is increased irt anti-Cd40 (times)
    *** cells: HEK293<xCd40> in BMS
    *** times: 0 30 300+ min
    *** source: 12374738-Fig-1d
  *** Nfkb2[Ab] cleavage[WB] is increased irt anti-Cd40 (times)
    *** cells: M1241 in BMS
    *** times: 0 8+ 24++ hr
    *** source: 15084608-Fig-5a
  *** Nfkb2[Ab] cleavage[WB] is increased irt anti-Cd40 (times)
    *** cells: mSpBCs in BMS
    *** times: 0 4+ 18++ hr
    *** source: 18997792-Fig-S4c
  *** Nfkb2[Ab] cleavage[WB] is increased irt anti-Cd40 (times)
    *** cells: mSpBCs in BMS
    *** times: 0 60+ 120+ 240++ min
    *** source: 18997792-Fig-5a
  *** Nfkb2[Ab] cleavage[WB] is increased irt Cd40L (times)
    *** cells: HEK293<xCd40> in BMS
    *** times: 0 30 300+ min
    *** source: 12374738-Fig-1d
  *** Nfkb2[Ab] cleavage[WB] is increased irt Cd40L (times)
    *** cells: mSpBCs in BMS
    *** times: 0 2+ 4+ 6++ hr
    *** source: 12374738-Fig-5a
  *** Nfkb2[Ab] infraction(nuclear)[WB] is increased irt anti-Cd40 (times)
    *** cells: HEK293<xCd40> in BMS
    *** times: 0 30 60 190+ 180++ 960+++ min
    *** comment: only Nfkb2-p52 is seen in NucFraction
    *** source: 12374738-Fig-4a
  *** Nfkb2[Ab] infraction(nuclear)[WB] is increased irt anti-Cd40 (times)
    *** cells: HEK293<xCd40> in BMS
    *** times: 0 30+ 240++ min
    *** inhibited by: xNik(del(624-947))"DN" [addition]
    *** source: 12374738-Fig-7a
  *** Nfkb2[Ab] infraction(nuclear)[WB] is increased irt Cd40L (times)
    *** cells: mSpBCs in BMS
    *** times: 0+ 30++ 120++ 240++ min
    *** inhibited by: MG132 [addition]
    *** source: 12374738-Fig-5b
  *** Nfkb2[Ab] infraction(nuclear)[WB] is increased irt Cd40L (times)
    *** cells: mSpBCs in BMS
    *** times: 0+ 30++ 300+++ min
    *** source: 12374738-Fig-6b
  *** Nfkb2[Ab] oligo-binding[EMSA] is increased irt anti-Cd40 (times)
    *** cells: HEK293<xCd40> in BMS
    *** times: 0 30 60 180+ 360++ 960++ min
    *** source: 12374738-Fig-4c
  *** Nfkb2[Ab] oligo-binding[EMSA] is increased irt anti-Cd40 (times)
    *** cells: HEK293<xCd40> in BMS
    *** times: 0 30 360+ min
    *** source: 12374738-Fig-4c
  *** Nfkb2[Ab] oligo-binding[EMSA] is increased irt Cd40L (5 hr)
    *** cells: mSpBCs in BMS
    *** source: 12374738-Fig-5d
  *** xNfkb2[tAb] cleavage[WB] is increased irt anti-Cd40 (15 hr)
    *** cells: HEK293<xCd40> in BMS
    *** inhibited by: xNfkb2(del(346-377))"GRR-domain-mut" [substitution]
    *** source: 12374738-Fig-2b
  *** xNfkb2[tAb] cleavage[WB] is increased irt anti-Cd40 (15 hr)
    *** cells: HEK293<xCd40> in BMS
    *** inhibited by: xNfkb2(S866A/S870A)"PEST-region-mut" [substitution]
    *** source: 12374738-Fig-2d
  *** xNfkb2[tAb] cleavage[WB] is increased irt anti-Cd40 (times)
    *** cells: HEK293<xCd40> in BMS
    *** times: 0 30 3+ 360+ min
    *** inhibited by: CHX [addition]
    *** source: 12374738-Fig-3a,3b
  *** Nik[Ab] prot-exp[WB] is increased irt anti-Cd40 (times)
    *** cells: mSpBCs in BMS
    *** times: 0 4+ 18++ hr
    *** source: 18997792-Fig-S4c
  *** Pik3rs[Ab] copptby[WB] Cd40[Ab] is increased irt Cd40L (times)
    *** cells: mBMDCs in BMS
    *** times: 0+ 5++ 10+++ min
    *** source: 11406619-Fig-1b
*** Rel--
  *** Rel[Ab] oligo-binding[EMSA] is increased irt Cd40L (12 hr)
    *** cells: CL01 in BMS "nuclear-extracts"
    *** oligo: "Nfkb" 5-GTGTCTGGACTCCCCCTCGCC-3
    *** enhanced by: IL4 [cotreatment]
    *** source: 10228008-Fig-7a
  *** Rel[Ab] oligo-binding[EMSA] is increased irt Cd40L (12 hr)
    *** cells: hTonsillarBCs in BMS "nuclear-extracts"
    *** oligo: "Nfkb" 5-GTGTCTGGACTCCCCCTCGCC-3
    *** enhanced by: IL4 [cotreatment]
    *** source: 10228008-Fig-7a
  *** Rel[Ab] oligo-binding[EMSA] is unchanged irt anti-Cd40 (times)
    *** cells: HEK293<xCd40> in BMS
    *** times: 0 30 360 min
    *** source: 12374738-Fig-4c
  *** Rel[Ab] oligo-binding[EMSA] is unchanged irt Cd40L (5 hr)
    *** cells: mSpBCs in BMS
    *** source: 12374738-Fig-5d
*** Rela--
  *** Rela[Ab] infraction(nuclear)[WB] is increased irt anti-Cd40 (times)
    *** cells: HEK293<xCd40> in BMS
    *** times: 0+ 30++ 60++ 180++ 480++ 960++ min
    *** source: 12374738-Fig-4a
  *** Rela[Ab] infraction(nuclear)[WB] is increased irt Cd40L (times)
    *** cells: mSpBCs in BMS
    *** times: 0 30+ 300+ min
    *** source: 12374738-Fig-6b
  *** Rela[Ab] oligo-binding[EMSA] is increased irt anti-Cd40 (2 hr)
    *** cells: RAMOS in BMS
    *** oligo: "Lta-Nfkb" 5-CCTGGGGGCTTCCCCGGG-3
    *** source: 9541585-Fig-2a
  *** Rela[Ab] oligo-binding[EMSA] is increased irt anti-Cd40 (30 min)
    *** cells: BL2 in BMS "nuclear-extracts"
    *** unaffected by: IL4 [cotreatment]
    *** source: 14978013-Fig-5
  *** Rela[Ab] oligo-binding[EMSA] is increased irt anti-Cd40 (times)
    *** cells: HEK293<xCd40> in BMS
    *** times: 0 30+ 360+ min
    *** source: 12374738-Fig-4c
  *** Rela[Ab] oligo-binding[EMSA] is increased irt Cd40L (12 hr)
    *** cells: CL01 in BMS "nuclear-extracts"
    *** oligo: "Nfkb" 5-GTGTCTGGACTCCCCCTCGCC-3
    *** enhanced by: IL4 [cotreatment]
    *** source: 10228008-Fig-7a
  *** Rela[Ab] oligo-binding[EMSA] is increased irt Cd40L (12 hr)
    *** cells: hTonsillarBCs in BMS "nuclear-extracts"
    *** oligo: "Nfkb" 5-GTGTCTGGACTCCCCCTCGCC-3
    *** enhanced by: IL4 [cotreatment]
    *** source: 10228008-Fig-7a
  *** Rela[Ab] oligo-binding[EMSA] is unchanged irt Cd40L (5 hr)
    *** cells: mSpBCs in BMS
    *** source: 12374738-Fig-5d
  *** Rela[Ab] oligo-binding[EMSA] is unchanged irt Cd40L (30 min)
    *** cells: hPBMonos in BMS
    *** source: 10395671-Fig-2
  *** Rela[Ab] oligo-binding[EMSA] is unchanged irt Cd40L (30 min)
    *** cells: hTonsillarBCs in BMS
    *** source: 10395671-Fig-2
  *** Relb[Ab] infraction(nuclear)[WB] is increased irt anti-Cd40 (times)
    *** cells: HEK293<xCd40> in BMS
    *** times: 0 30 240+ min
    *** inhibited by: xNik(del(624-947))"DN" [addition]
    *** source: 12374738-Fig-7a
  *** Relb[Ab] infraction(nuclear)[WB] is increased irt anti-Cd40 (times)
    *** cells: mSpBCs in BMS
    *** times: 0+ 60+ 120+ 240++ min
    *** comment: total protein not shown
    *** source: 18997792-Fig-5a
  *** Relb[Ab] infraction(nuclear)[WB] is increased irt Cd40L (times)
    *** cells: mSpBCs in BMS
    *** times: 0 30 300+ min
    *** source: 12374738-Fig-6b
*** Stat1--
  *** Stat1-gene mRNA[RTPCR] is  unchanged irt Cd40L (times)
    *** cells: hPDCs in BMS
    *** times: 0+ 3+ 15+ hr
    *** source: 12707322-Fig-6
  *** Stat1[Ab] oligo-binding[EMSA] is unchanged irt anti-Cd40 (30 min)
    *** cells: hPBMonos in BMS "nuclear-extracts"
    *** source: 10395671-Fig-6a
*** Stat2--
  *** Stat2[Ab] oligo-binding[EMSA] is unchanged irt anti-Cd40 (30 min)
    *** cells: hPBMonos in BMS "nuclear-extracts"
    *** source: 10395671-Fig-6a
*** Stat3--
  *** Stat3[Ab] infraction(nuclear)[WB] is increased irt anti-Cd40 (times)
    *** cells: BJAB in BMS
    *** times: 0 5 15+ 30+ 60+ min
    *** source: 9133417-Fig-5b
  *** Stat3[Ab] oligo-binding[EMSA] is unchanged irt anti-Cd40 (30 min)
    *** cells: hPBMonos in BMS "nuclear-extracts"
    *** source: 10395671-Fig-6a
  *** Stat3[Ab]IP Yphos[pYAb] is increased irt anti-Cd40 (10 min)
    *** cells: BJAB in BMS
    *** source: 9133417-Fig-5a
  *** Stat4[Ab] oligo-binding[EMSA] is unchanged irt anti-Cd40 (30 min)
    *** cells: hPBMonos in BMS "nuclear-extracts"
    *** source: 10395671-Fig-6a
*** Stat5--
  *** Stat5s[Ab] oligo-binding[EMSA] is increased irt anti-Cd40 (30 min)
    *** cells: hPBMonos in BMS "nuclear-extracts"
    *** source: 10395671-Fig-6a
*** Stat6--
  *** Stat6[Ab] oligo-binding[EMSA] is unchanged irt anti-Cd40 (30 min)
    *** cells: hPBMonos in BMS "nuclear-extracts"
    *** source: 10395671-Fig-6a
  *** Stat6[Ab] oligo-binding[EMSA] is unchanged irt Cd40L (12 hr)
    *** cells: CL01 in BMS "nuclear-extracts"
    *** oligo: GAS 5-GAGCTGTGATTTCCTAGGAAGACAAA-3
    *** source: 10228008-Fig-7a
  *** Stat6[Ab] oligo-binding[EMSA] is unchanged irt Cd40L (12 hr)
    *** cells: hTonsillarBCs in BMS "nuclear-extracts"
    *** oligo: GAS 5-GAGCTGTGATTTCCTAGGAAGACAAA-3
    *** source: 10228008-Fig-7a
  *** Stat6[Ab] snaggedby[WB] rIrf4[GST] is decreased irt anti-Cd40 (24 hr)
    *** cells: RAMOS in BMS
    *** source: 10601358-Fig-3a
*** Thymidine-inc
  *** DNA-synthesis[3H-Thymidine] is increased irt anti-Cd40 (48 hr)
    *** cells: mSpBCs in BMLS
    *** does not req: Peli1 [KO]
    *** source: 19734906-Fig-3b
  *** DNA-synthesis[3H-Thymidine] is increased irt anti-Cd40 (48 hr)
    *** cells: mSpBCs in BMS
    *** does not req: Ripk2 [KO]
    *** source: 11894097-Fig-2c
  *** DNA-synthesis[3H-Thymidine] is increased irt Cd40L (4 days)
    *** cells: hBCs in BMS "EBV transformed"
    *** enhanced by: C4bpa [cotreatment]
    *** source: 12818164-Fig-3a
  *** DNA-synthesis[3H-Thymidine] is increased irt Cd40L (4 days)
    *** cells: hPBMCs in BMS
    *** source: 12818164-Fig-3c
  *** DNA-synthesis[3H-Thymidine] is increased irt Cd40L (4 days)
    *** cells: hPBMCs in BMS
    *** source: 12818164-Fig-3d
  *** DNA-synthesis[3H-Thymidine] is increased irt Cd40L (4 days)
    *** cells: hPBMCs<Cd40L~null> in BMS
    *** source: 12818164-Fig-3c
  *** DNA-synthesis[3H-Thymidine] is unchanged irt Cd40L (4 days)
    *** cells: hPBMCs<Cd40~null> in BMS
    *** source: 12818164-Fig-3c
  *** DNA-synthesis[3H-Thymidine] is unchanged irt Cd40L (4 days)
    *** cells: hPBMCs<Nemo~null> in BMS
    *** source: 12818164-Fig-3d
*** Tnf--
  *** Tnf[Ab] secretion[ELISA] is increased irt Cd40L (24 hr)
    *** cells: mSpBCs in BMS
    *** inhibited by: kMekk1(1-1188)"del-kinase-domain" [addition]
    *** source: 17143273-Fig-6b
  *** Tnfaip3-gene mRNA[RTPCR] is increased irt anti-Cd40 (2 hr)
    *** cells: mSpCs<Cd40~null><xCd40> in BMS
    *** unaffected by: xCd40(del(230-247))"dTR6" [substitution]
    *** unaffected by: xCd40(T255A)"dTR23" [substitution]
    *** partially inhibited by: xCd40(del(230-247)/T255A)"dTRs" [substitution]
    *** source: 12354380-Fig-7c
  *** Tnfaip3-gene mRNA[RTPCR] is increased irt anti-Cd40 (2 hr)
    *** cells: mSpCs<Cd40~pos> in BMS
    *** source: 12354380-Fig-7c
*** Tpl2--
*** Traf1--
  *** Traf1[Ab] prot-exp[WB] is increased irt Cd40L (24 hr)
    *** cells: mBMDCs in BMLS
    *** source: 12370254-Fig-4b
*** Traf2--
  *** Traf2[Ab] prot-exp[WB] is decreased irt anti-Cd40 (times)
    *** cells: KMS28BM in BMS
    *** times: 0++ 10++ 30++ 240+ min
    *** reqs: Ciap1 and/or Ciap2 [KO]
    *** source: 18997792-Fig-5c
  *** Traf2[Ab] prot-exp[WB] is decreased irt anti-Cd40 (times)
    *** cells: mSpBCs in BMS
    *** times: 0++ 5++ 10++ 30++ 60+ min
    *** source: 17143273-Fig-4b
  *** Traf2[Ab] prot-exp[WB] is decreased irt anti-Cd40 (times)
    *** cells: mSpBCs in BMS
    *** times: 0++ 15++ 30+ 45+ 60+ min
    *** source: 18997792-Fig-S4b
  *** Traf2[Ab] prot-exp[WB] is decreased irt anti-Cd40 (times)
    *** cells: mSpBCs in BMS
    *** times: 0++ 60+ 120+ 240+ min
    *** source: 18997792-Fig-5a
  *** Traf2[Ab] prot-exp[WB] is decreased irt Cd40L (20 min)
    *** cells: mBMDCs in BMLS
    *** does not req: Traf1 [KO]
    *** source: 12370254-Fig-4b
  *** Traf2[Ab] prot-exp[WB] is decreased irt Cd40L (20 min)
    *** cells: mBMDCs in BMLS
    *** unaffected by: Cd40L [pretreatment]
    *** source: 12370254-Fig-4b
  *** Traf2[Ab] prot-exp[WB] is decreased irt Cd40L (times)
    *** cells: KMS28BM in BMS
    *** times: 0++ 30+ 240+ min
    *** reqs: Ciap1 and/or Ciap2 [KO]
    *** source: 18997792-Fig-5c
  *** Traf2[Ab] prot-exp[WB] is unchanged irt anti-Cd40 (times)
    *** cells: mSpBCs in BMS
    *** times: 0+ 5+ 10+ 30+ 60+ min
    *** source: 17143273-Fig-4b
  *** Traf3[Ab] prot-exp[WB] is decreased irt anti-Cd40 (4 hr)
    *** cells: mSpBCs in BMS
    *** reversed by: SmacMimetic [pretreatment]
    *** source: 18997792-Fig-5e
  *** Traf3[Ab] prot-exp[WB] is decreased irt anti-Cd40 (30 min)
    *** cells: A20 in BMS
    *** reversed by: MG132 [pretreatment]
    *** source: 18997792-Fig-S4a
  *** Traf3[Ab] prot-exp[WB] is decreased irt anti-Cd40 (times)
    *** cells: KMS28BM in BMS
    *** times: 0++ 10++ 30+ 240+ min
    *** reqs: Ciap1 and/or Ciap2 [KO]
    *** source: 18997792-Fig-5c
  *** Traf3[Ab] prot-exp[WB] is decreased irt anti-Cd40 (times)
    *** cells: mSpBCs in BMS
    *** times: 0++ 15+ 30+ 45+ 60+ min
    *** source: 18997792-Fig-S4b
  *** Traf3[Ab] prot-exp[WB] is decreased irt anti-Cd40 (times)
    *** cells: mSpBCs in BMS
    *** times: 0++ 30+ 240+ min
    *** reversed by: SmacMimetic [pretreatment]
    *** source: 18997792-Fig-5d
  *** Traf3[Ab] prot-exp[WB] is decreased irt anti-Cd40 (times)
    *** cells: mSpBCs in BMS
    *** times: 0+++ 60++ 120+ 240+ min
    *** source: 18997792-Fig-5a
  *** Traf3[Ab] prot-exp[WB] is decreased irt Cd40L (times)
    *** cells: KMS28BM in BMS
    *** times: 0++ 30+ 240 min
    *** reqs: Ciap1 and/or Ciap2 [KO]
    *** source: 18997792-Fig-5c
  *** Traf3[Ab]IP ubiq[K63UbAb] is unchanged irt anti-Cd40 (90 min)
    *** cells: mSpBCs in BMS
    *** source: 18997792-Fig-S7
  *** Traf3[Ab]IP ubiq[UbAb] is increased irt anti-Cd40 (90 min)
    *** cells: mSpBCs in BMS
    *** inhibited by: SmacMimetic [pretreatment]
    *** source: 18997792-Fig-S7
*** Traf6--
  *** Traf6[Ab] copptby[WB] Mekk1[Ab] is unchanged irt anti-Cd40 (times)
    *** cells: mSpBCs in BMS
    *** times: 0 5 10 30 60 min
    *** source: 17143273-Fig-4c
  *** Traf6[Ab] copptby[WB] Mekk1[Ab] is unchanged irt Cd40L (times)
    *** cells: mSpBCs in BMS
    *** times: 0 5 10 30 60 min
    *** source: 17143273-Fig-S7b
  *** Traf6[Ab] prot-exp[WB] is unchanged irt anti-Cd40 (times)
    *** cells: mSpBCs in BMS
    *** times: 0+ 2+ 5+ 10+ 30+ min
    *** unaffected by: SmacMimetic [addition]
    *** source: 18635759-Fig-5d
  *** xTraf6[tAb] copptby[WB] Traf2[Ab] is increased irt Cd40L (15 min)
    *** cells: HELA<xCd40(Q234A/E235A)"mT6"> in BMS
    *** inhibited by: xCd40(T254A)"mT2/T3" [substitution]
    *** source: 16260598-Fig-8d
  *** xTraf6[tAb] copptby[WB] Traf2[Ab] is increased irt Cd40L (times)
    *** cells: HELA<xCd40(Q234A/E235A)"mT6"> in BMS
    *** times: 0 10++ 15+ min
    *** source: 16260598-Fig-8c
