=================
Required Proteins
=================

Pin1--   ???

  *** xFos(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased irt Pdgf (5 hr)
    *** cells: NIH3T3 in BMLS
    *** enhanced by: xPin1 [addition]
    *** source: 16123044-Fig-4a


================
Protein Features
================

  *** xFos(209-380)[Gal4-DBD] Gal4-reporter[Luc] is increased irt Pdgf (4 hr)
    *** cells: NIH3T3 in BMLS
    *** inhibited by: xFos((209-380)/T232A/T325A/T331A/S374A) [substitution]
    *** source: 12972619-Fig-5b
  *** xFos(209-380)[Gal4-DBD] Gal4-reporter[Luc] is increased irt Pdgf (5 hr)
    *** cells: NIH3T3 in BMLS
    *** inhibited by: xFos((209-380)/T232A/T325A/T331A/S374A) [substitution]
    *** partially inhibited by: xFos((209-380)/T232A) [substitution]
    *** partially inhibited by: xFos((209-380)/T325A) [substitution]
    *** partially inhibited by: xFos((209-380)/T331A) [substitution]
    *** partially inhibited by: xFos((209-380)/T374A) [substitution]
    *** source: 12972619-Fig-8b
  *** xFos(209-380)[Gal4-DBD] Gal4-reporter[Luc] is increased irt Pdgf (5 hr)
    *** cells: NIH3T3 in BMLS
    *** inhibited by: rFos((209-380)/T232A/T325A/T331A/S374A) [substitution]
    *** source: 16123044-Fig-4b

===============
Phosphorylation
===============

  *** xFos[Ab] phos[WBMS] is increased irt Pdgf (30 min)
    *** cells: NIH3T3 in BMLS
    *** inhibited by: xFos(T232A/T325A/T331A/S374A) [substitution]
    *** source: 12972619-Fig-6a
  *** Fos[Ab] phos[WBMS-PPase] is increased irt Pdgf (times)
    *** cells: NIH3T3 in BMLS
    *** times: 0 10+ 30+ min
    *** source: 12972619-Fig-2e

========
Location
========

  *** Fos[Ab] infraction(nuclear)[WB] is increased irt Pdgf (times)
    *** cells: NIH3T3 in BMLS
    *** times: 0 30 60++ 120++ 240++ 360+ min
    *** source: 12972619-Fig-2a
  *** Fos[Ab] infraction(nuclear)[WB] is increased irt Pdgf (2 hr)
    *** cells: NIH3T3 in BMLS
    *** inhibited by: U0126 [addition]
    *** unaffected by: SP600125 [addition]
    *** unaffected by: SB203580 [addition]
    *** source: 12972619-Fig-2b


=========
Chemicals
=========

  *** xFos(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased irt Pdgf (tnr)
    *** cells: NIH3T3 in BMLS
    *** inhibited by: U0126 [addition]
    *** unaffected by: SP600125 [addition]
    *** unaffected by: SB203580 [addition]
    *** source: 12972619-Fig-3c
  *** xFos[Ab] phos[WBMS] is increased irt Pdgf (30 min)
    *** cells: NIH3T3 in BMLS
    *** inhibited by: U0126 [addition]
    *** source: 12972619-Fig-6a
  *** Fos[Ab] phos[WBMS] is increased irt Pdgf (30 min)
    *** cells: NIH3T3 in BMLS
    *** inhibited by: U0126 [addition]
    *** unaffected by: SP600125 [addition]
    *** unaffected by: SB203580 [addition]
    *** source: 12972619-Fig-2d
  *** Fos[Ab] prot-exp[WB] is increased irt Pdgf (times)
    *** cells: SWISS3T3 in BMLS
    *** times: 0 45+ 60+ 90++ 120++ 150++ 180++ 210++ min
    *** inhibited by: U0126 [addition]
    *** source: 12134156-Fig-6c

=========
no extras
=========

  *** xFos(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased irt Pdgf (4 hr)
    *** cells: NIH3T3 in BMLS
    *** source: 12972619-Fig-3b
  *** xFos[Gal4-DBD] Gal4-reporter[Luc] is increased irt Pdgf (4 hr)
    *** cells: NIH3T3 in BMLS
    *** source: 12972619-Fig-3b
