======================
Direct Phosphorylation
======================

  *** rTp53(1-42)[32P] phos[32P-ATP] is increased by rCsnk1d
    *** cells: none
    *** unaffected by: rTp53(S6A/S9A) [substitution]
    *** unaffected by: rTp53(S15A) [substitution]
    *** partially inhibited by: rTp53(S37A) [substitution]
    *** partially inhibited by: rTp53(S15A/S37A) [substitution]
    *** unaffected by: rTp53(T18A) [substitution]
    *** inhibited by: rTp53(S20A) [substitution]
    *** source: 10606744-Fig-1b 
  *** rTp53(1-42)[32P] phos[32P-ATP] is increased by rCsnk1d
    *** cells: none
    *** comment: enhanced by pre-phos with pDnapk
    *** source: 10606744-Fig-2b
  *** rTp53[32P] phos[32P-ATP] is increased by rCsnk1d
    *** cells: none
    *** comment: enhanced by pre-phos with pDnapk
    *** source: 10606744-Fig-3a


=====================================================================
phosphorylation of Tp53(T18) by Csnk1d requires pre-phos on Tp53(S15)
=====================================================================

  *** rTp53(2-46)[phosAb] phos(S15)[phosAb] is unchanged by rCsnk1d
    *** cells: none
    *** source: 10734067-Fig-4c
  *** rTp53(2-46)[phosAb] phos(T18)[phosAb] is unchanged by rCsnk1d
    *** cells: none
    *** source: 10734067-Fig-4c

  *** rTp53(2-46)[phosAb] phos(T18)[phosAb] is increased by (rCsnk1d + pDnapk)
    *** cells: none
    *** reqs: both [omissions]
    *** source: 10734067-Fig-4c

  *** sTp53(1-24)[32P] phos[32P-ATP] is unchanged by rCsnk1d
    *** cells: none
    *** source: 10734067-Fig-4a
  *** sTp53(1-24/pS15)[32P] phos[32P-ATP] is increased by rCsnk1d
    *** cells: none
    *** inhibited by: sTp53(1-24) [substitution]
    *** partially inhibited by: sTp53(1-24/pS15/T18A) [substitution]
    *** partially inhibited by: sTp53(1-24/pS6/pS15/T18A) [substitution]
    *** partially inhibited by: sTp53(1-24/pS9/pS15/T18A) [substitution]
    *** partially inhibited by: sTp53(1-24/pS15/pS18/S20A) [substitution]
    *** partially inhibited by: sTp53(1-24/pS9) [substitution]
    *** source: 10734067-Fig-4a

