======================
Relocation to Nucleus
======================

Src--

  *** Irf3[Ab] locatedin(nucleus)[IHC] is increased irt PolyIC (50 min)
    *** cells: mEFs<Src~null><Yes1~null><Fyn~null><xSrc> in BMS
    *** reqs: xSrc [omission]
    *** source: 16858407-Fig-1f
  *** Irf3[Ab] infraction(nuclear)[WB] is increased irt PolyIC (times)
    *** cells: mEFs<Src~null><Yes1~null><Fyn~null><xSrc> in BMS
    *** times: 0 10 20+ 40++ 50+++ min
    *** reqs: xSrc [omission]
    *** source: 16858407-Fig-1d

Traf3--

  *** Irf3[Ab] infraction(nuclear)[WB] is increased irt PolyIC (times)
    *** cells: mBMMs in BMS
    *** times: 0 45+ 90++ min
    *** partially reqs: Traf3 [KO]
    *** source: 16306936-Fig-2e

inhibited by Pin1--

  *** Irf3[Ab] locatedin(nucleus)[IHC] is increased irt PolyIC (tnr)
    *** cells: HEK293<xTLR3> in BMS
    *** inhibited by: xPin1 [addition]
    *** source: 16699525-Fig-1f

Tbk1-- and/or TnfR1--

  *** Irf3[Ab] infraction(nuclear)[WB] is increased irt PolyIC (times)
    *** cells: mBMMs in BMS
    *** times: 0 30+ 60++ min
    *** reqs: Tbk1 and/or TnfR1 [DKO]
    *** source: 15210743-Fig-2a

TLR3--

  *** Irf3[Ab] locatedin(nucleus)[IHC] is increased irt PolyIC (75 min)
    *** cells: RPE1 in BMS
    *** reqs: TLR3 [RNAi]
    *** source: 22611194-Fig-1c

chemicals

  *** Irf3[Ab] locatedin(nucleus)[IHC] is increased irt PolyIC (75 min)
    *** cells: RPE1 in BMS
    *** inhibited by: Leupeptin [pretreatment]
    *** inhibited by: Z-FA-FMK [pretreatment]
    *** source: 22611194-Fig-2c

no extras

  *** Irf3[Ab] infraction(nuclear)[WB] is increased irt PolyIC (times)
    *** cells: mBMMs in BMS
    *** times: 0 15+ 30++ 60++ 90 min
    *** source: 12354379-Fig-3a
  *** Irf3[Ab] locatedin(nucleus)[IHC] is increased irt PolyIC (times)
    *** cells: RPE1 in BMS
    *** times: 0+ 15+ 30+ 60++ 75+++ 90++ min
    *** source: 22611194-Fig-S1f
