===============
Kinase Activity
===============

  *** Jnks[Ab]IP IVKA(Jun)[32P-ATP] is increased irt PolyIC (30 min)
    *** cells: mBMMs in BMS
    *** source: 12354379-Fig-2c

===============
Phosphorylation
===============

not Ikke--

  *** Jnks[phosAb] phos(TPY)[phosAb] is increased irt PolyIC (times)
    *** cells: mEFs in BMS
    *** times: 0 10+ 20 min
    *** does not req: Ikke [KO]
    *** source: 15210742-Fig-4d

not Irak1--

  *** Jnks[phosAb] phos(TPY)[phosAb] is increased irt Poly-dIdC (times)
    *** cells: HEK293<xTLR3> in BMS
    *** times: 0+ 10+++ 20++ 30++ 60++ 120+ min
    *** does not req: Irak1 [fmut]
    *** source: 12609980-Fig-1b 

Mekk1--  ???

  *** Jnks[phosAb] phos(TPY)[phosAb] is increased irt PolyIC (times)
    *** cells: mESCs in BMS
    *** times: 0 10++ 30+ 60 min
    *** inhibited by: kMekk1(1-1188)"del-kinase-domain" [addition]
    *** source: 10805784-Fig-2

not Myd88--

  *** Jnks[phosAb] phos(TPY)[phosAb] is increased irt PolyIC (times)
    *** cells: mBMMs in BMS
    *** times: 0 15++ 30++ 45+ 90+ min
    *** does not req: Myd88 [KO]
    *** source: 11607032-Fig-6b

not Ripk1--

  *** Jnks[phosAb] phos(TPY)[phosAb] is increased irt PolyIC
    *** cells: mEFs in BMS
    *** times: 0 10+++ 30++ 60+ 120+ 480 min
    *** does not req: Ripk1 [KO]
    *** source: 15064760-Fig-5b

Tak1--  ???

  *** Jnks[phosAb] phos(TPY)[phosAb] is increased irt PolyIC
    *** cells: mEFs in BMS
    *** times: 0 15 30 60++ 120+ 240 min
    *** comment: delayed by 60 min in Tak1-null mEFs [KO]
    *** comment: delayed by 60 min in Tab1-null mEFs [KO]
    *** comment: delayed by 60 min in Tab2-null mEFs [KO]
    *** source: 16260493-Fig-3e

not Tbk1--

  *** Jnks[phosAb] phos(TPY)[phosAb] is increased irt PolyIC (times)
    *** cells: mEFs in BMS
    *** times: 0 10+ 20 min
    *** does not req: Tbk1 [KO]
    *** source: 15210742-Fig-4d

TLR3--

  *** Jnks[phosAb] phos(TPY)[phosAb] is increased irt Poly-dIdC (times)
    *** cells: HEK293I1A<Irak1~fmut><xTLR3> in BMS
    *** times: 0+ 30++ 60++ 120+ min
    *** reqs: xTLR3 [omission]
    *** source: 12609980-Fig-1c 

Tradd--

  *** Jnks[phosAb] phos(TPY)[phosAb] is increased irt PolyIC (times)
    *** cells: mEFs in BMS
    *** times: 0 15 30 60 120+ min
    *** reqs: Tradd [KO]
    *** source: 18641654-Fig-4c
  *** Jnks[phosAb] phos(TPY)[phosAb] is increased irt PolyIC (times)
    *** cells: mBMDCs in BMS
    *** times: 0 10 20+ 30+ 60+ 90+ min
    *** reqs: Tradd [KO]
    *** source: 18641654-Fig-4d

not Traf6--

  *** Jnks[phosAb] phos(TPY)[phosAb] is increased irt PolyIC (times)
    *** cells: mBMMs in BMS
    *** times: 0 10++ 30++ 60+ min
    *** does not req: Traf6 [KO]
    *** source: 16306937-Fig-4a
  *** Jnks[phosAb] phos(TPY)[phosAb] is increased irt PolyIC (times)
    *** cells: mSMacs in BMS
    *** times: 0 10 20+ 30+ 60 90 min
    *** does not req: Traf6 [KO]
    *** source: 15322147-Fig-2a

chemicals

  *** Jnks[phosAb] phos(TPY)[phosAb] is increased irt PolyIC (20 min)
    *** cells: hMDDCs in BMS
    *** unaffected by: PP2 [pretreatment]
    *** unaffected by: PP3 [pretreatment]
    *** source: 16858407-Fig-2b
  *** Jnks[phosAb] phos(TPY)[phosAb] is increased irt PolyIC (times)
    *** cells: mBMMs in BMS
    *** times: 0 5+ 10++ 30++ 60 min
    *** unaffected by: SmacMimetic [pretreatment]
    *** source: 19898473-Fig-1a
  *** Jnks[phosAb] phos(TPY)[phosAb] is increased irt PolyIC (times)
    *** cells: RAW2647 in BMS
    *** times: 0 30+ 60+ min
    *** unaffected by: SmacMimetic [pretreatment]
    *** source: 19898473-Fig-S1


no extras

  *** Jnks[phosAb] phos(TPY)[phosAb] is increased irt PolyIC (1 hr)
    *** cells: U373<xCd14> in BMS
    *** source: 12062447-Fig-4a
  *** Jnks[phosAb] phos(TPY)[phosAb] is increased irt PolyIC (times)
    *** cells: hMDDCs in BMS
    *** times: 0+ 10++ 20++ 40++ 60+ min
    *** source: 16858407-Fig-2a
  *** Jnks[phosAb] phos(TPY)[phosAb] is increased irt PolyIC (times)
    *** cells: mBMMs in BMS "immortalized"
    *** times: 0 5 10 20 40+ 60+ min
    *** source: 22065573-Fig-3a
