All human type I IFNs (IFNa, Ifnb, and ifnw) bind to a cell surface receptor consisting of two transmembrane proteins, type I IFN receptor (ifnar) 1 [2153461] and ifnar2 [8181059], which associate upon binding. IFN binds with high affinity to ifnar2, probably recruiting ifnar1 subsequently. 11698684(C)

experimental evidence needed
