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Syk Yphos is increased irt Csf1
===============================

  *** Syk[Ab]IP Yphos[pYAb] is increased irt Csf1 (times)
    *** cells: mBMPOs in BMS "Csf1-and-Rankl-deprived"
    *** times: 0+ 2+++ 5+ 15+ 30+ min
    *** source: 18691974-Fig-2b

reqs Dap12

  *** Syk[Ab]IP Yphos[pYAb] is increased irt Csf1 (times)
    *** cells: mBMMs in BMS "Csf1-starved"
    *** times: 0 2+ 5++ min
    *** reqs: Dap12 [KO]
    *** source: 19503107-Fig-S3
  *** Syk[Ab]IP Yphos[pYAb] is increased irt Csf1 (5 min)
    *** cells: mBMPOs<Dap12~null><xDap12> in BMS "Csf1-and-Rankl-deprived"
    *** reqs: xDap12 [omission]
    *** source: 18691974-Fig-2e
  *** Syk[Ab]IP Yphos[pYAb] is increased irt Csf1 (times)
    *** cells: mBMPOs in BMS "Csf1-and-Rankl-deprived"
    *** times: 0+ 2++ 5++ min
    *** bkg reqs: Dap12 [KO]
    *** source: 18691974-Fig-2d

reqs Dap12-Yphos

  *** Syk[Ab]IP Yphos[pYAb] is increased irt Csf1 (5 min)
    *** cells: mBMPOs<Dap12~null><xDap12> in BMS "Csf1-and-Rankl-deprived"
    *** inhibited by: xDap12(Y92F/Y103F) [substitution]
    *** source: 18691974-Fig-4b

reqs Syk kinase activity

  *** xSyk[Ab]IP Yphos[pYAb] is increased irt Csf1 (5 min)
    *** cells: mBMPOs<Syk~null><xSyk> in BMS "Csf1-and-Rankl-deprived"
    *** inhibited by: xSyk(K402R)"KD" [substitution]
    *** source: 18691974-Fig-3d

reqs Syk SH2 domain

  *** xSyk[Ab]IP Yphos[pYAb] is increased irt Csf1 (5 min)
    *** cells: mBMPOs<Syk~null><xSyk> in BMS "Csf1-and-Rankl-deprived"
    *** inhibited by: xSyk(R195A) [substitution]
    *** source: 18691974-Fig-4c

=========
Chemicals
=========

  *** Syk[Ab]IP Yphos[pYAb] is increased irt Csf1 (5 min)
    *** cells: mBMPOs in BMS "Csf1-and-Rankl-deprived"
    *** inhibited by: SU6656 [addition]
    *** source: 18691974-Fig-3c

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physical interaction with Dap12
===============================

  *** Syk[Ab] copptby[WB] xDap12[tAb] is increased irt Csf1 (5 min)
    *** cells: mBMPOs<Dap12~null><xDap12> in BMS "Csf1-and-Rankl-deprived"
    *** inhibited by: xDap12(Y92F/Y103F) [substitution]
    *** source: 18691974-Fig-4d
