not Brca1--

  *** Atm{phos(S1981)}[phosAb] locatedin(subnuclear-bodies)[IHC] is detectable
    *** cells: hFibros in BMS "treated with IR for 1 hr"
    *** does not req: Brca1 [RNAi]
    *** source: 19001859-Fig-2a

Mdc1--

  *** Atm{phos(S1981)}[phosAb] locatedin(subnuclear-bodies)[IHC] is increased irt IR (1 hr)
    *** cells: mEFs in BMS
    *** reqs: Mdc1 [KO]
    *** source: 16427009-Fig-4c
  *** Atm{phos(S1981)}[phosAb] locatedin(subnuclear-bodies)[IHC] is detectable
    *** cells: hFibros in BMS "treated with IR for 1 hr"
    *** partially reqs: Mdc1 [RNAi]
    *** comment: req based on measurement of cells with >5 foci
    *** comment: difference is not apparent in images
    *** source: 19001859-Fig-2a
  *** Atm{phos(S1981)}[phosAb] locatedin(subnuclear-bodies)[IHC] is detectable
    *** cells: HELA in BMS "treated with IR for 1 hr"
    *** reqs: Mdc1 [RNAi]
    *** source: 16427009-Fig-S4
  *** Atm{phos(S1981)}[phosAb] locatedin(subnuclear-bodies)[IHC] is detectable
    *** cells: mEFs<Mdc1~null><xMdc1> in BMS "treated with IR for tnr"
    *** reqs: xMdc1 [omission]
    *** inhibited by: xMdc1(del(56-124))"delFHA" [substitution]
    *** inhibited by: xMdc1(del(1894-2089))"delBRCT" [substitution]
    *** source: 16427009-Fig-5f


Nbs1--  ????

  *** Atm{phos(S367)}[phosAb] locatedin(DSBs)[IHC] is increased irt Ni64Ions (1 hr)
    *** cells: NBS03LA<Nbs1~fmut> in BMS
    *** comment: intensity of staining is less than that seen in AG1522D
    *** source: 21149446-Fig-S6a
  *** Atm{phos(S1981)}[phosAb] locatedin(DSBs)[IHC] is increased irt Ni64Ions (1 hr)
    *** cells: NBS03LA<Nbs1~fmut> in BMS
    *** comment: intensity of staining is less than that seen in AG1522D
    *** source: 21149446-Fig-S6a

Tp53bp2--  ????

  *** Atm{phos(S1981)}[phosAb] locatedin(subnuclear-bodies)[IHC] is detectable
    *** cells: hFibros in BMS "treated with IR for 1 hr"
    *** partially reqs: Tp53bp1 [RNAi]
    *** comment: req based on measurement of cells with >5 foci
    *** comment: difference is vaguely apparent in images
    *** source: 19001859-Fig-2a

  *** xAtm{phos(S1981)}[phosAb] locatedin(subnuclear-bodies)[IHC] is increased irt IR (times)
    *** cells: AT1ABR<Atm~fmut><xAtm> in BMS
    *** times: 0 30+ 360+ min
    *** unaffected by: xAtm(S367A) [substitution]
    *** unaffected by: xAtm(S1983A) [substitution]
    *** inhibited by: xAtm(S1981A) [substitution]
    *** comment: author found inhibition by S367A and S1983A by counting number of foci per cell
    *** source: 16858402-Fig-6a

  *** Atm{phos(S367)}[phosAb] locatedin(DSBs)[IHC] is increased irt Ni64Ions (1 hr)
    *** cells: AG1522D in BMS
    *** source: 21149446-Fig-S6a
  *** Atm{phos(S367)}[phosAb] locatedin(DSBs)[IHC] is increased irt XenonIons (times)
    *** cells: AG1522D in BMS
    *** times: 0 5+ 60++ 1440+ min
    *** comment: colocates with H2ax-phos(S140)
    *** source: 21149446-Fig-8
  *** Atm{phos(S367)}[phosAb] locatedin(subnuclear-bodies)[IHC] is detectable
    *** cells: HE49 in BMS "treated with IR for 1 hr"
    *** comment: colocates with Atm-phos(S1981)
    *** comment: colocates with H2ax-phos(S140)
    *** comment: colocates with Tp53bp1
    *** source: 21149446-Fig-S3
  *** Atm{phos(S367)}[phosAb] locatedin(subnuclear-bodies)[IHC] is detectable
    *** cells: NotReported in BMS "treated with IR for tnr"
    *** comment: colocates with Atm-phos(S367)
    *** source: 21149446-Fig-7a
  *** Atm{phos(S367)}[phosAb] locatedin(subnuclear-bodies)[IHC] is detectable
    *** cells: NotReported in BMS "treated with IR for tnr"
    *** comment: colocates with H2ax-phos(S140)
    *** source: 21149446-Fig-7a
  *** Atm{phos(S1981)}[phosAb] locatedin(DSBs)[IHC] is increased irt C12Ions (10 min)
    *** cells: AG1522D in BMS
    *** comment: colocates with Atm-phos(S367)
    *** source: 21149446-Fig-S5a
  *** Atm{phos(S1981)}[phosAb] locatedin(DSBs)[IHC] is increased irt Ni64Ions (1 hr)
    *** cells: AG1522D in BMS
    *** source: 21149446-Fig-S6a
  *** Atm{phos(S1981)}[phosAb] locatedin(DSBs)[IHC] is increased irt Ni64Ions (10 min)
    *** cells: AG1522D in BMS
    *** comment: colocates with Atm-phos(S367)
    *** source: 21149446-Fig-S5b
  *** Atm{phos(S1981)}[phosAb] locatedin(DSBs)[IHC] is increased irt XenonIons (times)
    *** cells: AG1522D in BMS
    *** times: 0 5++ 60++ 1440+ min
    *** comment: colocates with H2ax-phos(S140)
    *** source: 21149446-Fig-S4b
  *** Atm{phos(S1981)}[phosAb] locatedin(subnuclear-bodies)[IHC] is detectable
    *** cells: HE49 in BMS "treated with IR for 1 hr"
    *** comment: colocates with Atm-phos(S367)
    *** source: 21149446-Fig-S3
  *** Atm{phos(S1981)}[phosAb] locatedin(subnuclear-bodies)[IHC] is detectable
    *** cells: NotReported in BMS "treated with IR for tnr"
    *** comment: colocates with H2ax-phos(S140)
    *** source: 21149446-Fig-7a
  *** Atm{phos(S2996)}[phosAb] locatedin(DSBs)[IHC] is increased irt Au197Ions (times)
    *** cells: AG1522D in BMS
    *** times: 0 1+ 12+ hr
    *** comment: colocates with H2ax-phos(S140)
    *** source: 21149446-Fig-9
  *** Atm[Ab] locatedin(DSBs)[IHC] is increased irt XenonIons (times)
    *** cells: AG1522D in BMS
    *** times: 0 5++ 60++ 1440+ min
    *** comment: colocates with H2ax-phos(S140)
    *** source: 21149446-Fig-S4a
  *** xAtm[XFP] locatedin(DSBs)[IHC] is increased irt U238Ions (30 min)
    *** cells: GM8523HTERT<Atm~fmut> in BMS
    *** comment: colocates with H2ax-phos(S140)
    *** unaffected by: xAtm(S367A) [substitution]
    *** unaffected by: xAtm(S1981A) [substitution]
    *** source: 21149446-Fig-10
