=====================
Phosphorylation sites
=====================

S593A/S666A

  *** xTax1bp1[Ab]IP phos[32Pi] is increased irt Tnf (15 min)
    *** cells: mEFs<Tax1bp1~null><xTax1bp1> in BMS
    *** inhibited by: xTax1bp1(S593A/S666A) [substitution]
    *** source: 21765415-Fig-2h
  *** xTax1bp1[tAb] phos[WBMS] is increased irt Tnf (15 min)
    *** cells: mEFs<Tax1bp1~null><xTax1bp1> in BMS
    *** inhibited by: xTax1bp1(S593A/S666A) [substitution]
    *** source: 21765415-Fig-S5

S666A

  *** xTax1bp1[tAb] phos[WBMS] is increased irt Tnf (15 min)
    *** cells: mEFs<Tax1bp1~null><xTax1bp1> in BMS
    *** unaffected by: xTax1bp1(S593A) [substitution]
    *** inhibited by: xTax1bp1(S593A/S666A) [substitution]
    *** inhibited by: xTax1bp1(S666A) [substitution]
    *** source: 21765415-Fig-2f

S593

  *** Tax1bp1[phosAb] phos(S593)[phosAb] is increased irt Tnf (times)
    *** cells: mBMMs in BMS
    *** times: 0 15+ 60+ min
    *** comment: total protein increase and WBMS correlates with phos increase
    *** source: 21765415-Fig-2k
  *** Tax1bp1[phosAb] phos(S593)[phosAb] is increased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0 15+ 30+ 60+ 120+ min
    *** comment: total protein controls not performed
    *** source: 21765415-Fig-2j

=================
Required proteins
=================

not Akt1-- or Akt2--

  *** xTax1bp1[Ab] phos[WBMS] is increased irt Tnf (times)
    *** cells: mEFs<xTax1bp1> in BMS
    *** times: 0 15+ 30+ min
    *** does not req: Akt1 or Akt2 [DKO]
    *** source: 21765415-Fig-S3

Ikk1--  kinase activity

  *** xTax1bp1[tAb] phos[WBMS] is increased irt Tnf (15 min)
    *** cells: mEFs<Ikk1~null><xIkk1><xTax1bp1> in BMS
    *** reqs: xIkk1 [omission]
    *** inhibited by: xIkk1(K44M)"KD" [substitution]
    *** source: 21765415-Fig-1h
  *** xTax1bp1[tAb] phos[WBMS] is increased irt Tnf (15 min)
    *** cells: mEFs<xTax1bp1> in BMS
    *** reqs: Ikk1 [KO]
    *** source: 21765415-Fig-1e
  *** Tax1bp1[Ab]IP phos[WBMS] is increased irt Tnf (15 min)
    *** cells: mEFs<Ikk1~null><xIkk1> in BMS
    *** inhibited by: xIkk1(K44M)"KD" [substitution]
    *** source: 21765415-Fig-1g


not Ikk2--

  *** xTax1bp1[tAb] phos[WBMS] is increased irt Tnf (15 min)
    *** cells: mEFs<xTax1bp1> in BMS
    *** does not req: Ikk2 [KO]
    *** source: 21765415-Fig-1e

not Nemo--

  *** xTax1bp1[tAb] phos[WBMS] is increased irt Tnf (15 min)
    *** cells: mEFs<xTax1bp1> in BMS
    *** does not req: Nemo [KO]
    *** source: 21765415-Fig-1e

no extras

  *** Tax1bp1[Ab]IP phos[32Pi] is increased irt Tnf (15 min)
    *** cells: mEFs in BMS
    *** source: 21765415-Fig-1c
  *** xTax1bp1[tAb] phos[WBMS-PPase] is increased irt Tnf (30 min)
    *** cells: mEFs<xTax1bp1> in BMS
    *** source: 21765415-Fig-1a

