======================
Direct Phosphorylation
======================

  *** rMnk1[32P] phos[32P-ATP] is increased by rErk2(mnr)"CA"
    *** cells: none
    *** source: 11154262-Fig-1a
  *** rMnk1[32P] phos[32P-ATP] is increased by rErk2{act}
    *** cells: none
    *** source: 9155017-Fig-5a

===================
Protein Association
===================

  *** rErk2[35S] boundby[WB] rMnk1[GST] is detectable
    *** cells: none
    *** source: 9155017-Fig-3b
  *** Erks[Ab] copptby[WB] xMnk1[GST] is detectable
    *** cells: HEK293T<xMnk1> in BMS
    *** source: 9155017-Fig-3c

===================================================
Activation in response to overexpressed active Erk2
===================================================

  *** xMnk1[His]IP IVKA(Eif4e)[32P-ATP] is increased itpo (xMek1(mnr)"CA" + xErk2)
    *** cells: Ecoli<xMnk1> in BugMedium
    *** source: 17130135-Fig-1a

========================================================
Phosphorylation in response to overexpressed active Erk2
========================================================

  *** xMnk1[phosAb] phos(T257)[phosAb] is increased itpo (xMek1(mnr)"CA" + xErk2)
    *** cells: Ecoli<xMnk1> in BugMedium
    *** source: 17130135-Fig-1c
  *** xMnk1[phosAb] phos(T257)[phosAb] is increased itpo (xMek1(mnr)"CA" + xErk2)
    *** cells: Ecoli<xMnk1> in BugMedium
    *** unaffected by: xMnk1(T250A) [substitution]
    *** inhibited by: xMnk1(T257A) [substitution]
    *** source: 17130135-Fig-1d
  *** xMnk1[phosAb] phos(T250/T257)[phosAb] is increased itpo (xMek1(mnr)"CA" + xErk2)
    *** cells: Ecoli<xMnk1> in BugMedium
    *** inhibited by: xMnk1(T250A) [substitution]
    *** inhibited by: xMnk1(T257A) [substitution]
    *** source: 17130135-Fig-1d
