===========================
P38a Direct Phosphorylation
===========================

  *** rP38a[32P] phos[32P-ATP] is increased by rMkk6
    *** cells: none
    *** source: 9430721-Fig-7a
  *** rP38a[32P] phos[32P-ATP] is increased by rMkk6
    *** cells: none
    *** inhibited by: rP38?(T180A/Y182F) [substitution]
    *** source: 8622669-Fig-6b
  *** rP38a[32P] phos[32P-ATP] is increased by rMkk6
    *** cells: none
    *** source: 8622669-Fig-6a
  *** rP38a[32P] phos[32P-ATP] is increased by rMkk6
    *** cells: none
    *** enhanced by: rTaok1(1-416)"CA" [addition]
    *** source: 9786855-Fig-4b
  *** rP38a[32P] phos[32P-ATP] is increased by rMkk6
    *** cells: none
    *** enhanced by: rTaok2(1-320)"CA" [addition]
    *** source: 10497253-Fig-2a

======================
P38a Direct Activation
======================

  *** rP38a[His] IVKA(Atf2)[32P-ATP] is increased by rMkk6
    *** cells: none
    *** source: 8663074-Fig-2
  *** rP38a IVKA(Atf2)[32P-ATP] is increased by rMkk6
    *** cells: none
    *** source: 9384583-Fig-1b

==========
Activation
==========

  *** xP38a[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xMkk6
    *** cells: NIH3T3 in BMS
    *** source: 10669751-Fig-5a
  *** xP38a[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xMkk6
    *** cells: COS7 in BMS
    *** source: 8663524-Fig-7
  *** xP38a[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xMkk6(S207E/T211E)"CA"
    *** cells: COS7 in BMS
    *** source: 9430721-Fig-2b
  *** xP38a[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xMkk6(S207E/T211E)"CA"
    *** cells: COS7 in BMS
    *** source: 9430721-Fig-6c
  *** xP38a[tAb]IP IVKA(Elk1)[32P-ATP] is increased itpo xMkk6(S207E/T211E)"CA"
    *** cells: COS7 in BMS
    *** source: 9430721-Fig-8d
  *** xP38a[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xMkk6
    *** cells: COS7 in BMS
    *** source: 9384583-Fig-1a
  *** P38a[Ab]IP IVKA(Atf2)[32P-ATP] is increased itpo xMkk6(S207E/T211E)
    *** cells: COS1 in BMS
    *** source: 8622669-Fig-7c
  *** xP38a[Ab]IP IVKA(Atf2)[32P-ATP] is increased itpo xMkk6(S207E/T211E)
    *** cells: COS1 in BMS
    *** source: 8622669-Fig-7c
  *** xP38a[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xMkk6(S207E/T211E)
    *** cells: COS1 in BMS
    *** inhibited by: xMkk6(K82A) [substitution]
    *** source: 8622669-Fig-7b
  *** xP38a[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xMkk6(S207E/T211E)
    *** cells: COS1 in BMS
    *** inhibited by: xP38?(T180A/Y182F) [substitution]
    *** source: 8622669-Fig-7b
-------------------------------------------------------------------------------
  *** xP38b[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xMkk6
    *** cells: COS7 in BMS
    *** source: 8663524-Fig-7
  *** xP38b[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xMkk6(S207E/T211E)"CA"
    *** cells: COS7 in BMS
    *** source: 9430721-Fig-2b
  *** xP38b[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xMkk6(S207E/T211E)"CA"
    *** cells: COS7 in BMS
    *** source: 9430721-Fig-6c
  *** xP38b[tAb]IP IVKA(Elk1)[32P-ATP] is increased itpo xMkk6(S207E/T211E)"CA"
    *** cells: COS7 in BMS
    *** source: 9430721-Fig-8d
-------------------------------------------------------------------------------
  *** xP38g[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xMkk6(S207E/T211E)"CA"
    *** cells: COS7 in BMS
    *** source: 9430721-Fig-2b
  *** xP38g[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xMkk6(S207E/T211E)"CA"
    *** cells: COS7 in BMS
    *** source: 9430721-Fig-6c
  *** xP38g[tAb]IP IVKA(Elk1)[32P-ATP] is increased itpo xMkk6(S207E/T211E)"CA"
    *** cells: COS7 in BMS
    *** source: 9430721-Fig-8d
  *** xP38g[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xMkk6
    *** cells: NIH3T3 in BMS
    *** source: 10669751-Fig-5b
  *** rP38g IVKA(MBP)[32P-ATP] is increased by rMkk6
    *** cells: none
    *** source: 9384583-Fig-1b
  *** xP38g[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xMkk6
    *** cells: COS7 in BMS
    *** source: 9384583-Fig-1a
-------------------------------------------------------------------------------
  *** xP38d[tAb]IP IVKA(Atf2)[32P-ATP] is unchanged itpo xMkk6
    *** cells: NIH3T3 in BMS
    *** source: 10669751-Fig-5b

===============
Phosphorylation
===============

  *** xP38s[phosAb] phos(TGY)[phosAb] is increased itpo xMkk6(mnr)"CA"
    *** cells: COS7<xSumo1> in BMS
    *** inhibited by: xP38?(mnr)"DN" [addition]
    *** source: 17897103-Fig-2a
  *** xP38s[phosAb] phos(TGY)[phosAb] is increased itpo xMkk6(mnr)"CA"
    *** cells: COS7<xSumo1> in BMS
    *** source: 17897103-Fig-1
  *** xP38s[phosAb] phos(TGY)[phosAb] is increased itpo xMkk6(mnr)"CA"
    *** cells: COS7<xSumo1> in BMS
    *** source: 17897103-Fig-3a
  *** xP38s[phosAb] phos(TGY)[phosAb] is increased itpo xMkk6(mnr)"CA"
    *** cells: COS7<xSumo1> in BMS
    *** unaffected by: SB202190 [addition]
    *** source: 17897103-Fig-2b
  *** xP38s[phosAb] phos(TGY)[phosAb] is increased itpo xMkk6(mnr)"CA"
    *** cells: COS7<xSumo1> in BMS
    *** unaffected by: SB202190 [addition]
    *** source: 17897103-Fig-3b
  *** xP38s[phosAb] phos(TGY)[phosAb] is increased itpo xMkk6(mnr)"CA"
    *** cells: COS7<xSumo1> in BMS
    *** unaffected by: xStat1(K703R) [substitution]
    *** unaffected by: xStat1(Y701F) [substitution]
    *** unaffected by: xStat1(S727A) [substitution]
    *** source: 17897103-Fig-4a
-------------------------------------------------------------------------------
  *** rP38b[32P] phos[32P-ATP] is increased by rMkk6
    *** cells: none
    *** source: 9430721-Fig-7a
-------------------------------------------------------------------------------
  *** rP38g[32P] phos[32P-ATP] is increased by rMkk6
    *** cells: none
    *** source: 9430721-Fig-7a

