Tnk2 to EgfR  max between 30 and 60 min

  *** Tnk2[Ab] copptby[WB] EgfR[Ab] is increased irt Egf (times)
    *** cells: BE2C in BMLS
    *** times: 0 5+ 30++ 60++ min
    *** source: 17182860(D)
  *** Tnk2[Ab] copptby[WB] EgfR[Ab] is increased irt Egf (times)
    *** cells: COS7 in BMLS
    *** times: 0 30++ 60++ 120++ 240++ 360+ min
    *** source: 17182860(D)
  *** Tnk2[Ab] copptby[WB] EgfR[Ab] is increased irt Egf (times)
    *** cells: COS7 in BMLS
    *** times: 0 1 10+ 30++ 60++ min
    *** source: 17182860(D)
  *** Tnk2[Ab] copptby[WB] EgfR[Ab] is increased irt Egf (times)
    *** cells: H358 in BMLS
    *** times: 0 10 30+ 60++ 120++ 180++ min
    *** source: 17182860(D)
  *** Tnk2[Ab] copptby[WB] EgfR[Ab] is increased irt Egf (times)
    *** cells: HELA in BMLS
    *** times: 0 5+ 30+ 60++ min
    *** source: 17182860(D)
  *** Tnk2[Ab] copptby[WB] EgfR[Ab] is increased irt Egf (times)
    *** cells: MDAMB231 in BMLS
    *** times: 0 30+ 90++ 180++ min
    *** source: 17182860(D)
  *** EgfR[Ab] copptby[WB] xTnk2[tAb] is increased irt Egf (times)
    *** cells: COS7 in BMLS
    *** times: 0 30+ 60+ min
    *** source: 17182860(D)
  *** xTnk2[tAb] copptby[WB] EgfR[Ab] is increased irt Egf (times)
    *** cells: COS7 in BMLS
    *** times: 0 1+ 30+ min
    *** inhibited by: AG1478 [addition]
    *** source: 17182860(D)
  *** xTnk2[XFP] colocwith[IHC] EgfR[Ab] is increased irt Egf (times)
    *** cells: COS7 in BMLS
    *** times: 0 5+ 30++ min
    *** source: 17182860(D)

  *** xTnk2[tAb] copptby[WB] xEgfR[Ab] is increased irt Egf (times)
    *** cells: CHO in BMLS
    *** times: 0+ 10++ 60++ min
    *** inhibited by: xEgfR(K721R)"KD" [substitution]
    *** unaffected by: xEgfR(Y1045F)"Cbl-binding-site-mut" [substitution]
    *** inhibited by: xEgfR(Y1173F)"Shp2-binding-site-mut" [substitution]
    *** source: 17182860(D)

Yphos

  *** Tnk2[Ab]IP Yphos[pYAb] is increased irt Egf (times)
    *** cells: HEK293 in BMS
    *** times: 0 1+ 2++ 5+ min
    *** source: 11394904-Fig-2a
  *** Tnk2[MS] Yphos[pYAb-ppt] is increased irt Egf (times)
    *** cells: HELA in BMLS
    *** times: 1+ 5+ 10+ 20 min
    *** source: 15314609(D)
  *** xTnk2[Ab]IP Yphos[pYAb] is unchanged irt Egf (5 min)
    *** cells: HER14 in BMLS
    *** source: 16777958-Fig-2c
  *** Tnk2[Ab]IP phos(Y284)[phosAb] is increased irt Egf (5 min)
    *** cells: HER14 in BMLS
    *** source: 16777958-Fig-2c
  *** Tnk2[Ab]IP Yphos[pYAb] is increased irt Egf (times)
    *** cells: HEK293 in BMS
    *** times: 0 1+++ 3++ 10+ 20 60 min
    *** source: 8647288-Fig-3

