  *** Tollip[Ab] copptby[WB] IL1R1[Ab] is increased irt IL1b (times)
    *** cells: EL4 in BMS
    *** times: 0 1 2+ 5 10 min
    *** source: 10854325-Fig-2b

  *** Irak1[Ab] copptby[WB] Tollip[Ab] is decreased irt IL1b (5 min)
    *** cells: EL4 in BMS
    *** source: 10854325-Fig-3b

  *** xTollip[Ab] copptby[WB] (xIL1R1[tAb] + xIL1Rap[tAb]) is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xTollip(del(48-178)) [substitution]
    *** unaffected by: xTollip(47-274) [substitution]
    *** inhibited by: xTollip(1-229) [substitution]
    *** inhibited by: xTollip(1-178) [substitution]
    *** source: 10854325-Fig-5b
  *** xTollip[Ab] copptby[WB] (xIL1R1[tAb] + xIL1Rap[tAb]) is detectable
    *** cells: HEK293T<xIrak1(D340N)"KD"> in BMS
    *** inhibited by: xIrak1(WT) [addition]
    *** inhibited by: xIrak1(T66A) [addition]
    *** source: 10854325-Fig-4a

  *** xTollip[tAb] copptby[WB] Irak1[Ab] is decreased irt IL1b (5 min)
    *** cells: HEK293<xIL1R1> in BMS
    *** source: 10854325-Fig-3a
  *** xTollip[tAb] copptby[WB] xIL1R1[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 10854325-Fig-2a
  *** xTollip[tAb] copptby[WB] xIL1Rap[tAb] is detectable
    *** cells: HEK293T in BMS
    *** enhanced by: xIL1R1 [addition]
    *** source: 10854325-Fig-2a


