==========================
semi-direct ubiquitination
==========================

  *** Traf2[Ab]IP ubiq[UbAb] is increased itpo (xUbc13 + xUbiq)
    *** cells: HELA in BMS
    *** source: 12591926-Fig-1a
  *** Traf2[Ab]IP upshift[WBMS] is increased itpo (xUbc13 + xUbiq)
    *** cells: HELA in BMS
    *** source: 12591926-Fig-1a

========================
evidence for K63 linkage
========================

  *** xTraf2[Ab]IP ubiq[UbAb] is increased itpo (xUbc13 + xUbiq)
    *** cells: HELA in BMS
    *** inhibited by: xUbiq(K63R) [addition]
    *** unaffected by: xUbiq(K48R) [addition]
    *** source: 12591926-Fig-1a

  *** xTraf2[tAb]IP ubiq[tUbAb] is detectable
    *** cells: HELA<xUbiq> in BMS
    *** enhanced by: xUbc13 [addition]
    *** unaffected by: xUbc13(C87A) [addition]
    *** source: 14713952-Fig-3b
  *** xTraf2[Ab]IP ubiq[UbAb] is increased itpo (xUbc13 + xUbiq)
    *** cells: HELA in BMS
    *** inhibited by: xUbc13(C87A)"E2-inactive" [addition]
    *** source: 12591926-Fig-1a
