===============
Phosphorylation
===============

Erk2--

  *** Fos[phosAb] phos(T325)[phosAb] is increased irt Egf (5 min)
    *** cells: HELA<Erk1~null><Erk2~null><xErk2> in BMLS
    *** reqs: xErk2 [omission]
    *** partially inhibited by: xErk2(L232A) [substitution]
    *** partially inhibited by: xErk2(Y261A) [substitution]
    *** unaffected by: xErk2(D319N) [substitution]
    *** source: 16051177-Fig-2a
  *** xFos[phosAb] phos(T325)[phosAb] is increased irt Egf (5 min)
    *** cells: HELA<Erk1~null><Erk2~null><xErk2><xFos> in BMLS
    *** reqs: xErk2 [omission]
    *** source: 16051177-Fig-S1d

no extras--

  *** xFos[phosAb] phos(T325)[phosAb] is increased irt Egf (5 min)
    *** cells: HELA<xFos> in BMLS
    *** source: 16051177-Fig-S1d
  *** Fos[phosAb] phos(T325)[phosAb] is increased irt Egf (5 min)
    *** cells: HELA in BMLS
    *** source: 16051177-Fig-2a

contradiction

  *** Fos[phosAb] phos(T325)[phosAb] is unchanged irt Egf (5 min)
    *** cells: SWISS3T3 in BMLS
    *** source: 12134156-Fig-6a

chemicals

  *** xFos[phosAb] phos(T325)[phosAb] is increased irt Egf (5 min)
    *** cells: NIH3T3<xFos> in BMLS
    *** inhibited by: U0126 [pretreatment]
    *** source: 14673150-Fig-1b

Fos features

  *** xFos(S362D/S374D)[phosAb] phos(T325)[phosAb] is increased irt Egf (5 min)
    *** cells: NIH3T3 in BMS
    *** inhibited by: xFos(S362D/S374D/T343A) [substitution]
    *** inhibited by: xFos(S362D/S374D/Y345A) [substitution]
    *** source: 12134156-Fig-5e
  *** xFos[phosAb] phos(T325)[phosAb] is increased irt Egf (5 min)
    *** cells: NIH3T3 in BMS
    *** bkg inhibited by: xFos(T343A) [substitution]
    *** bkg inhibited by: xFos(Y345A) [substitution]
    *** source: 12134156-Fig-5d
  *** xFos[phosAb] phos(T325)[phosAb] is increased irt Egf (5 min)
    *** cells: NIH3T3 in BMS
    *** unaffected by: rFos(S362D/S374D) [substitution]
    *** source: 12134156-Fig-5b

=============
Oligo-binding
=============

  *** Fos[Ab] oligo-binding[EMSA] is increased irt Egf (10 min)
    *** cells: HEK293T<xEgfR> in BMLS
    *** inhibited by: xArf4(T31N)"DN" [substitution]
    *** source: 12446727-Fig-6c
