====================
Protein Associations
====================

Cbl--

  *** xPak1[Ab] copptby[WB] xCbl[tAb] is undetectable
    *** cells: HEK293T<xCbl><xPak1> in BMS
    *** source: 16407834-Fig-2b

Gnb1--

  *** xPak1[tAb] copptby[WB] xGnb1[Ab] is detectable
    *** cells: HEK293<xGng2> in BMS
    *** unaffected by: xArhGef6 [addition]
    *** enhanced by: xArhGef6 + xCdc42 [addition]
    *** source: 12887923-Fig-2a

Grb2--

  *** Pak1[Ab] copptby[WB] Grb2[Ab] is detectable
    *** cells: HACAT in BMS
    *** source: 12522133-Fig-2b
  *** Pak1[Ab] copptby[WB] Grb2[Ab] is detectable
    *** cells: JURKAT<Pten~null> in BMS
    *** source: 12522133-Fig-2b

Nck1--

  *** xPak1[Ab] copptby[WB] Nck1[Ab] is detectable
    *** cells: HEK293T in BMLS
    *** partially inhibited by: 8CPTcAMP [addition]
    *** partially inhibited by: xPrkg1 [addition]
    *** inhibited by: 8CPTcAMP + xPrkg1 [addition]
    *** comment: inversely correlates with Pak1[phosAb] phos(S21)[phosAb]
    *** source: 16490784(D)
  *** xPak1[Ab] copptby[WB] Nck1[Ab] is detectable
    *** cells: HEK293T in BMLS
    *** unaffected by: xPak1(K299R)"KD" [substitution]
    *** source: 16490784(D)
  *** Pak1[Ab] copptby[WB] xNck1[Ab] is detectable
    *** cells: COS7 in BMS
    *** source: 8824201-Fig-3a
  *** Pak1[Ab] copptby[WB] xNck1[Ab] is detectable
    *** cells: L6 in BMLS
    *** unaffected by: Pdgf (5 min) [stim]
    *** unaffected by: Ins (5 min) [stim]
    *** source: 8798379-Fig-1
  *** xPak1[Ab] snaggedby[WB] rNck1[GST] is detectable
    *** cells: HEK293 in BMS
    *** source: 8798379-Fig-4
  *** xPak1[tAb] snaggedby[WB] rNck1[GST] is detectable
    *** cells: COS7 in BMS
    *** source: 8824201-Fig-1

not Geft--

  *** Pak1[Ab] copptby[WB] xGeft[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 18851832-Fig-4d

not Hras--

  *** xPak1[Ab] copptby[WB] xHras(G12V)"CA"[tAb] is undetectable
    *** cells: COS7 in BMS
    *** source: 8910292(D)

not Rhoa--

  *** xPak1[Ab] copptby[WB] xRhoa(Q61L)"CA"[tAb] is undetectable
    *** cells: COS7 in BMS
    *** source: 8910292(D)
  *** xPak1[tAb] snaggedby[WB] rRhoa(Q63L)"CA"[GST] is undetectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-2

not Rhog--

  *** xPak1[tAb] snaggedby[WB] rRhog(Q61L)"CA"[GST] is undetectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-2

========
Location
========

Focal Complexes

  *** xPak1[Ab] locatedin(peripheral-focal-complexes)[IHC] is detectable
    *** cells: HELA<xPak1><xCdc42(G12V)> in BMS
    *** inhibited by: xArhGef7(W32P/W44G) [addition]
    *** source: 9659915-Fig-5a
  *** xPak1[Ab] locatedin(peripheral-focal-complexes)[IHC] is detectable
    *** cells: HELA<xPak1><xCdc42(G12V)> in BMS
    *** inhibited by: xPak1(P191G/R192A)"Pix-binding-defective" [substitution]
    *** source: 9659915-Fig-5a

