=================
Kinase Activation
=================

  *** Ampk[Ab]IP IVKA(peptide)[32P-ATP] is increased irt Vegf (times)
    *** cells: hAECs in BSS
    *** times: 0+ 5+++ 15+ 30+ min
    *** unaffected by: Wortmannin [addition]
    *** unaffected by: PP1 [addition]
    *** inhibited by: U73122 [addition]
    *** inhibited by: STO609 [addition]
    *** source: 17276402(D)


=============================
Phosphorylation on LRTSC site
=============================

not Akt1--

  *** Ampkas[phosAb] phos(LRTSC)[phosAb] is increased irt Vegf (times)
    *** cells: bAECs in BMLS
    *** times: 0+ 2++ 5++ min
    *** does not req: Akt1 [RNAi]
    *** source: 17519230-Fig-6b


Camkk2--

  *** Ampkas[phosAb] phos(LRTSC)[phosAb] is increased irt Vegf (times)
    *** cells: bAECs in BMLS
    *** times: 0+ 2++ 5++ 15++ min
    *** bkg reqs: Camkk2 [RNAi]
    *** source: 17519230-Fig-2b

not Rac1--

  *** Ampkas[phosAb] phos(LRTSC)[phosAb] is increased irt Vegf (times)
    *** cells: bAECs in BMLS
    *** times: 0+ 2++ 5++ min
    *** does not req: Rac1 [RNAi]
    *** source: 17519230-Fig-8a

VegfR2--

  *** Ampkas[phosAb] phos(LRTSC)[phosAb] is increased irt Vegf (times)
    *** cells: bAECs in BMLS
    *** times: 0+ 5++ 15++ min
    *** reqs: VegfR2 [RNAi]
    *** source: 17519230-Fig-2a

chemicals

  *** Ampkas[phosAb] phos(LRTSC)[phosAb] is increased irt Vegf (5 min)
    *** cells: bAECs in BMLS
    *** inhibited by: Genistein [pretreatment]
    *** inhibited by: PP2 [pretreatment]
    *** unaffected by: CsA [pretreatment]
    *** unaffected by: SB203580 [pretreatment]
    *** source: 17519230-Fig-1b
  *** Ampkas[phosAb] phos(LRTSC)[phosAb] is increased irt Vegf (5 min)
    *** cells: bAECs in BMLS
    *** unaffected by: Wortmannin [pretreatment]
    *** source: 17519230-Fig-1d
  *** Ampkas[phosAb] phos(LRTSC)[phosAb] is increased irt Vegf (2 min)
    *** cells: bAECs in BMLS
    *** inhibited by: STO609 [addition]
    *** source: 17519230-Fig-2a

no extras

  *** Ampkas[phosAb] phos(LRTSC)[phosAb] is increased irt Vegf (times)
    *** cells: bAECs in BMLS
    *** times: 0 1+ 2++ 5+++ 15++ 30+ min
    *** source: 17519230-Fig-1a






