======================
Phosphorylation on T68
======================

Atm--  ???

  *** Chek2[Ab]IP phos(T68)[phosAb] is increased irt UV (2 hr)
    *** cells: hLymphoblasts<Atm~fmut> in BMS
    *** comment: response is less than that seen in normal hLymphoblasts
    *** source: 10973490-Fig-4c
  *** Chek2[phosAb] phos(T68)[phosAb] is unchanged irt UV (1 hr)
    *** cells: hFibros<Atm~fmut> in BMS
    *** source: 16327781-Fig-1a

Atr--

  *** Chek2[phosAb] phos(T68)[phosAb] is unchanged irt UV (1 hr)
    *** cells: hFibros<Atr~fmut> in BMS
    *** source: 16327781-Fig-1a

no extras

  *** Chek2[Ab]IP phos(T68)[phosAb] is increased irt UV (2 hr)
    *** cells: HEK293T in BMS
    *** source: 10973490-Fig-4a
  *** Chek2[phosAb] phos(T68)[phosAb] is increased irt UV (1 hr)
    *** cells: HELA in BMS
    *** source: 16327781-Fig-1a
  *** Chek2[Ab]IP phos(T68)[phosAb] is increased irt UV (2 hr)
    *** cells: hLymphoblasts in BMS
    *** source: 10973490-Fig-4c
  *** Chek2[phosAb] phos(T68)[phosAb] is increased irt UV (1 hr)
    *** cells: U2OS in BMS
    *** comment: response is significantly less than that caused by IR
    *** source: 16327781-Fig-1b
  *** Chek2[phosAb] phos(T68)[phosAb] is increased irt UV (1 hr)
    *** cells: U2OS in BMS
    *** comment: response is significantly less than that caused by IR
    *** source: 16327781-Fig-S1b
  *** Chek2[phosAb] phos(T68)[phosAb] is increased irt UV (1 hr)
    *** cells: HELA in BMS
    *** comment: response is significantly less than that caused by IR
    *** source: 14695167-Fig-2b


===============
Kinase Activity
===============

  *** Chek2[Ab]IP IVKA(Cdc25c)[32P-ATP] is increased irt UV (2 hr)
    *** cells: HEK293T in BMS
    *** source: 9836640-Fig-3e

