===============================
Direct phosphorylation by P38a
===============================

on T69/T71

  *** rAtf2[phosAb] phos(T69/T71)[phosAb] is increased by rP38a{act}
    *** cells: none
    *** comment: rP38a was activated with Mkk6
    *** source: 15304344-Fig-2
  *** Atf2[phosAb] phos(T69/T71)[phosAb] is detectable
    *** cells: mEFs in BMS
    *** inhibited by: SB203580 [addition]
    *** source: 15304344-Fig-5a

on T71

  *** rAtf2[phosAb] phos(T71)[phosAb] is increased by rP38a{act}
    *** cells: none
    *** comment: rP38a was activated with Mkk6
    *** source: 15304344-Fig-2
  *** Atf2[phosAb] phos(T71)[phosAb] is detectable
    *** cells: mEFs in BMS
    *** partially inhibited by: SB203580 [addition]
    *** source: 15304344-Fig-5a

not on S90

  *** rAtf2[phosAb] phos(S90)[phosAb] is unchanged by rP38a{act}
    *** cells: none
    *** comment: rP38a was activated with Mkk6
    *** source: 15304344-Fig-2

total phos

  *** rAtf2(1-253) phos[32P-ATP] is increased by rP38a{act}
    *** cells: none
    *** source: 9155018-Fig-8a
  *** rAtf2[32P] phos[32P-ATP] is increased by (rMkk6 + rP38a)
    *** cells: none
    *** partially reqs: rMkk6 [omission]
    *** reqs: rP38a [omission]
    *** inhibited by: rP38a(T180A/Y182F) [substitution]
    *** source: 8622669-Fig-6c
  *** rAtf2[32P] phos[32P-ATP] is increased by rP38a
    *** cells: none
    *** inhibited by: SB203580 [addition]
    *** source: 9430721-Fig-4
  *** rAtf2[32P] phos[32P-ATP] is increased by rP38a
    *** cells: none
    *** inhibited by: rP38a(T180A/Y182F) [substitution]
    *** enhanced by: rMkk4 [addition]
    *** source: 7839144-Fig-3b
  *** rAtf2[32P] phos[32P-ATP] is increased by rP38a
    *** cells: none
    *** inhibited by: rAtf2(T69A/T71A) [substitution]
    *** source: 7535770-Fig-1a
  *** rAtf2(1-109)[32P] phos[32P-ATP] is increased by rP38a
    *** cells: none
    *** inhibited by: SB202190 [addition]
    *** source: 8663524-Fig-4
  *** rAtf2(1-109)[32P] phos[32P-ATP] is increased by rP38a
    *** cells: none
    *** source: 8663524-Fig-3
  *** rAtf2[phosAb] phos(S71)[phosAb] is increased by rP38a{act}
    *** cells: none
    *** source: 11896587-Fig-4b

===========================
Semi-direct phosphorylation
===========================

  *** rAtf2[32P] phos[32P-ATP] is increased by xP38a{act}[tAb]IP
    *** cells: none
    *** IPfrom: COS1 in BMS "treated with UV for tnr"
    *** source: 8622669-Fig-4e
  *** rAtf2[32P] phos[32P-ATP] is increased by xP38?[tAb]IP
    *** cells: none
    *** IPfrom: H1299<Tp53~null> in BMS "treated with UV for 1 hr"
    *** comment: increase requires UV treatment [omission]
    *** source: 10581258-Fig-3a
  *** rAtf2(1-109)[32P] phos[32P-ATP] is increased by xP38a[Ab]IP
    *** cells: none
    *** IPfrom: COS7<xP38a> in BMS "treated with UV"
    *** source: 9111305-Fig-1a
  *** rAtf2[32P] phos[32P-ATP] is increased by xP38a[Ab]IP
    *** cells: none
    *** IPfrom: COS7<xP38a> in BMS "treated with UV"
    *** source: 9111305-Fig-1a

===================
Protein Association
===================

  *** xP38a[tAb] snaggedby[WB] rAtf2(1-109)[GST] is detectable
    *** cells: NotReported in BMS
    *** source: 7535770-Fig-1b

=========================
Activation itpo P38a{act}
=========================

  *** xAtf2(TAD)[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xP38a
    *** cells: CHO in BMS
    *** source: 8663524-Fig-8
  *** xAtf2[Gal4-DBD] Gal4-reporter[Luc] is increased itpo (xMkk3(S189E/T193E) + xP38a)
    *** cells: CHO in BMS
    *** source: 8622669-Fig-4b
  *** xAtf2(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xP38a
    *** cells: CHO in BMS
    *** enhanced by: xMkk3(S189E/T193E)"CA" [addition]
    *** enhanced by: xMkk6(S207E/T211E)"CA" [addition]
    *** source: 8663524-Fig-9

==============================
Direct phosphorylation by P38b
===============================

on T69/T71

  *** rAtf2[phosAb] phos(T69/T71)[phosAb] is increased by rP38b{act}
    *** cells: none
    *** comment: rP38b was activated with Mkk6
    *** source: 15304344-Fig-2
  *** Atf2[phosAb] phos(T69/T71)[phosAb] is detectable
    *** cells: mEFs in BMS
    *** inhibited by: SB203580 [addition]
    *** source: 15304344-Fig-5a

on T71

  *** rAtf2[phosAb] phos(T71)[phosAb] is increased by rP38b{act}
    *** cells: none
    *** comment: rP38b was activated with Mkk6
    *** source: 15304344-Fig-2
  *** Atf2[phosAb] phos(T71)[phosAb] is detectable
    *** cells: mEFs in BMS
    *** partially inhibited by: SB203580 [addition]
    *** source: 15304344-Fig-5a

not on S90

  *** rAtf2[phosAb] phos(S90)[phosAb] is unchanged by rP38b{act}
    *** cells: none
    *** comment: rP38b was activated with Mkk6
    *** source: 15304344-Fig-2

total phos

  *** rAtf2[32P] phos[32P-ATP] is increased by rP38b
    *** cells: none
    *** inhibited by: SB203580 [addition]
    *** source: 9430721-Fig-4
  *** rAtf2[32P] phos[32P-ATP] is increased by rP38b
    *** cells: none
    *** source: 9430721-Fig-2a
  *** rAtf2(1-109)[32P] phos[32P-ATP] is increased by rP38b
    *** cells: none
    *** inhibited by: SB202190 [addition]
    *** source: 8663524-Fig-4
  *** rAtf2(1-109)[32P] phos[32P-ATP] is increased by rP38b
    *** cells: none
    *** source: 8663524-Fig-3


=====================
activation itpo xP38b
=====================

  *** xAtf2(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xP38b
    *** cells: CHO in BMS
    *** inhibited by: xP38b(T188A/Y190F)"KD" [substitution]
    *** source: 8663524-Fig-8
  *** xAtf2(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xP38b
    *** cells: CHO in BMS
    *** unaffected by: xMkk3(S189E/T193E)"CA" [addition]
    *** enhanced by: xMkk6(S207E/T211E)"CA" [addition]
    *** source: 8663524-Fig-9



  *** rAtf2[32P] phos[32P-ATP] is increased by rP38g
    *** cells: none
    *** unaffected by: SB203580 [addition]
    *** source: 9430721-Fig-4



