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Phosphorylation on T251
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Rac1--

  *** Mkk4[phosAb] phos(T261)[phosAb] is increased irt IL6 (15 min)
    *** cells: HEPG2 in BMS
    *** inhibited by: xRac1(T17N) [addition]
    *** source: 11335711-Fig-5a

Chemicals

  *** Mkk4[phosAb] phos(T261)[phosAb] is increased irt IL6 (15 min)
    *** cells: HEPG2 in BMS
    *** times: 0+ 5++ 10+ min
    *** unaffected by: Rottlerin [pretreatment]
    *** source: 11335711-Fig-5d

No extras

  *** Mkk4[phosAb] phos(T261)[phosAb] is increased irt IL6 (times)
    *** cells: HEPG2 in BMLS
    *** times: 0 5+ 10+ 20 min
    *** source: 10727406-Fig-3a

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Evidence Required
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(1) Mkk4-phos(T261) represents activated Mkk4
(2) Mkk4 location in response to IL6
