===========================
Phosphorylation on Tyrosine
===========================

IL4R--

  *** xFes[Ab]IP Yphos[pYAb] is increased irt IL4 (tnr)
    *** cells: COS7<xIL4R> in BMLS
    *** unaffected by: xIL4R(1-625)"N" [substitution]
    *** inhibited by: xIL4R(1-520)"M2" [substitution]
    *** inhibited by: xIL4R(1-431)"P" [substitution]
    *** source: 8916957-Fig-7a

Jak1--

  *** xFes[tAb]IP Yphos[pYAb] is increased irt IL4 (15 min)
    *** cells: HELA<Jak1~null><xJak1> in BMS
    *** reqs: xJak1 [omission]
    *** source: 11160325-Fig-2b

No Extras--

  *** xFes(K590E)[tAb]IP Yphos[pYAb] is increased irt IL4 (times)
    *** cells: M1241 in BMS
    *** times: 0 1+ 5+ 15+ 30+ 60+ min
    *** source: 11160325-Fig-2a
  *** Fes[Ab]IP Yphos[pYAb] is increased irt IL4 (times)
    *** cells: BAF3 in BMS
    *** times: 0 1+ 5+ 15+ 30+ 60+ min
    *** source: 11160325-Fig-1a

========================
Location in IL4R complex
========================

  *** IL4R[Ab] copptby[WB] Fes[Ab] is increased irt IL4 (times)
    *** cells: BAF3 in BMS
    *** times: 0 1+ 5+ 15+ 30+ 60+ min
    *** source: 11160325-Fig-1b
  *** xFes[Ab] copptby[WB] xIL4R[Ab] is detectable-but unchanged irt IL4 (tnr)
    *** cells: COS7 in BMLS
    *** unaffected by: xIL4R(1-625)"N" [substitution]
    *** unaffected by: xIL4R(1-520)"M2" [substitution]
    *** unaffected by: xIL4R(1-431)"P" [substitution]
    *** source: 8916957-Fig-7c

========================================
Coppt with other members of IL4R complex
========================================

Pi3k--

  *** Fes[Ab] copptby[WB] Pik3rs[Ab] is increased irt IL4 (times)
    *** cells: CTLL2 in BMLS
    *** times: 0 1+ 5++ 15 min
    *** source: 8916957-Fig-2
  *** Fes[Ab] copptby[WB] Pik3rs[Ab] is increased irt IL4 (times)
    *** cells: HT2 in BMLS
    *** times: 0 1+ 5 15 min
    *** source: 8916957-Fig-2


