========
Location
========

  *** xMnk2[XFP] infraction(cytoplasmic)[WB] is detectable
    *** cells: HEK293<xMnk2> in BMS
    *** source: 12897141-Fig-5b
  *** xMnk2[XFP] infraction(nuclear)[WB] is undetectable
    *** cells: HEK293<xMnk2> in BMS
    *** unaffected by: xMnk2(R447A/R448A) [substitution]
    *** reversed by: xMnk2(1-455) [substitution]
    *** unaffected by: xMnk2((1-455)/R447A/R448A) [substitution]
    *** unaffected by: xMnk2(L444A) [substitution]
    *** unaffected by: xMnk2(1-446) [substitution]
    *** source: 12897141-Fig-6c
  *** xMnk2[XFP] locatedin(cytoplasm)[IHC] is detectable
    *** cells: HEK293<xMnk1> in BMS
    *** comment: xMnk2 location is unaffected by 4 hr LMB treatment
    *** source: 12897141-Fig-6a
  *** xMnk2[XFP] locatedin(cytoplasm)[IHC] is undetectable
    *** cells: HEK293<xMnk2> in BMS
    *** source: 12897141-Fig-5a

  *** xMnk2(1-70)[XFP] infraction(nuclear)[WB] is detectable
    *** cells: HEK293<xMnk2(1-70)> in BMS
    *** inhibited by: xMnk2(1-60) [substitution]
    *** source: 12897141-Fig-5d

===============
Kinase Activity
===============

  *** xMnk2[tAb]IP IVKA(Eif4e)[32P-ATP] is detectable
    *** cells: HEK293<xMnk2> in BMLS
    *** source: 12897141-Fig-3g
  *** xMnk2[tAb]IP IVKA(Eif4e)[32P-ATP] is detectable
    *** cells: HEK293<xMnk2> in BMS
    *** inhibited by: xMnk2(R447A/R448A) [substitution]
    *** inhibited by: xMnk2(L444A) [substitution]
    *** unaffected by: xMnk2(1-455) [substitution]
    *** inhibited by: xMnk2(1-446) [substitution]
    *** source: 12897141-Fig-4e

===============
Phosphorylation
===============

  *** xMnk2[tAb]IP phos(TPELTT)[phosAb] is detectable
    *** cells: HEK293<xMnk2> in BMS
    *** inhibited by: xMnk2(R447A/R448A) [substitution]
    *** inhibited by: xMnk2(L444A) [substitution]
    *** unaffected by: xMnk2(1-455) [substitution]
    *** inhibited by: xMnk2(1-446) [substitution]
    *** source: 12897141-Fig-4d
  *** xMnk2[tAb]IP phos(TPELTT)[phosAb] is detectable
    *** cells: HEK293<xMnk2> in BMLS
    *** source: 12897141-Fig-3f
