===============
Kinase Activity ???
===============

  *** Jak1[Ab]IP IVKA(auto)[32P-ATP] is unchanged irt (IL6 + IL6Rsol) (10 min) 
    *** cells: BAFB03<xGp130> in BMLS
    *** source: 8134389-Fig-2c
  *** Jak1[Ab]IP IVKA(auto)[32P-ATP] is unchanged irt (IL6 + IL6Rsol) (10 min) 
    *** cells: M1 in BMLS
    *** source: 8134389-Fig-2c

===========================
Phosphorylation on Tyrosine
===========================

not Jak2--

  *** Jak1[Ab]IP Yphos[pYAb] is increased irt (IL6 + IL6Rsol) (15 min)
    *** cells: GAMMA2A<Jak2~null> in BMS
    *** source: 7537214-Fig-2b
  *** Jak1[Ab]IP Yphos[pYAb] is increased irt (IL6 + IL6Rsol) (15 min)
    *** cells: GAMMA2A<Jak2~null><xJak2> in BMS
    *** does not req: xJak2 [omission]
    *** unaffected by: xJak2(mnr)"KD" [substitution]
    *** source: 7537214-Fig-7a
  *** Jak1[Ab]IP Yphos[pYAb] is increased irt (IL6 + IL6Rsol) (15 min)
    *** cells: U1D<Tyk2~null> in BMS
    *** source: 7537214-Fig-2b

not Tyk2--

  *** Jak1[Ab]IP Yphos[pYAb] is increased irt (IL6 + IL6Rsol) (5 min)
    *** cells: EW1 in BMLS
    *** source: 8272873-Fig-2a
  *** Jak1[Ab]IP Yphos[pYAb] is increased irt (IL6 + IL6Rsol) (10 min)
    *** cells: BAFB03<xGp130> in BMLS
    *** source: 8134389-Fig-2a
  *** Jak1[Ab]IP Yphos[pYAb] is increased irt (IL6 + IL6Rsol) (15 min)
    *** cells: 2C4 in BMS
    *** source: 7537214-Fig-7a
  *** Jak1[Ab]IP Yphos[pYAb] is increased irt (IL6 + IL6Rsol) (15 min)
    *** cells: 2FTGH in BMS
    *** source: 7537214-Fig-2b

inhibited by Ptprec--

  *** Jak1[phosAb]IP Yphos[pYAb] is increased irt IL6 (5 min)
    *** cells: M1 in BMS
    *** partially inhibited by: xPtprec [addition]
    *** unaffected by: xPtprec(D245A) [addition]
    *** source: 10859312-Fig-5a

No extras

  *** xJak1[Ab]IP Yphos[pYAb] is increased irt (IL6 + IL6Rsol) (15 min)
    *** cells: U4A<Jak1~null><xJak1> in BMS
    *** source: 7537214-Fig-2b
  *** Jak1[Ab]IP Yphos[pYAb] is increased irt IL6 (10 min)
    *** cells: HEPG2 in BMS
    *** source: 8272872-Fig-2c
  *** Jak1[Ab]IP Yphos[pYAb] is increased irt IL6 (15 min)
    *** cells: 2FTGH in BMS
    *** source: 7537214-Fig-1b
  *** xJak1[Ab]IP Yphos[pYAb] is increased irt IL6 (20 min)
    *** cells: U4A<Jak1~null><xJak1> in BMS
    *** source: 15935617-Fig-3b
  *** Jak1[Ab]IP Yphos[pYAb] is increased irt IL6 (times)
    *** cells: HEPG2 in BMS
    *** times: 0 2+ 5+ 15+ 30+ 60 min
    *** source: 8272872-Fig-2a

Contradictions

  *** Jak1[Ab]IP Yphos[pYAb] is unchanged irt (IL6 + IL6Rsol) (5 min)
    *** cells: SKMES in BMLS
    *** source: 8272873-Fig-2c
  *** Jak1[Ab]IP Yphos[pYAb] is unchanged irt (IL6 + IL6Rsol) (10 min)
    *** cells: M1 in BMLS
    *** source: 8134389-Fig-2a
  *** Jak1[Ab]IP Yphos[pYAb] is unchanged irt (IL6 + IL6Rsol) (times)
    *** cells: M1 in BMLS
    *** times: 0 2 5 15 30 min
    *** source: 8134389-Fig-2b

================
Coprecipitations
================

  *** xJak1[Ab] copptby[WB] xShp2[Ab] is detectable-but unchanged irt (IL6 + IL6Rsol) (15 min)
    *** cells: U4A<Jak1~null><xJak1> in BMS
    *** source: 9794795-Fig-4a
