==========
EgfR coppt
==========

  *** xEgfR[Ab] copptby[WB] Stat1[Ab] is increased irt Egf (15 min)
    *** cells: hESKs<xEgfR> in BMLS "Egf and BPE starved"
    *** source: 15284024-Fig-5a
  *** Stat1[Ab] copptby[WB] EgfR[Ab] is detectable
    *** cells: A431 in BMLS
    *** unaffected by: Egf (5,15,30,60,120 min) [stim]
    *** source: 10358079-Fig-3a
  *** xStat1[tAb] copptby[WB] xEgfR[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12070153-Fig-4d

=====
Yphos
=====

  *** xStat1[tAb]IP Yphos[pYAb] is increased irt Egf (15 min)
    *** cells: COS7 in BMS
    *** source: 9083098-Fig-1
  *** Stat1[Ab]IP Yphos[pYAb] is increased irt Egf (10 min)
    *** cells: A431 in BMLS
    *** inhibited by: PP1 [addition]
    *** inhibited by: CGP77675 [addition]
    *** source: 10358079-Fig-6b
  *** Stat1[Ab]IP Yphos[pYAb] is increased irt Egf (times)
    *** cells: A431 in BMLS
    *** times: 0 5++ 15++ 30+ 60+ 120+ min
    *** source: 10358079-Fig-2a

==========
phos(Y701)
==========

  *** xStat1[phosAb] phos(Y701)[phosAb] is increased irt Egf (15 min)
    *** cells: COS1 in BMS
    *** source: 11278353-Fig-3b
  *** Stat1[Ab]IP phos(Y701)[phosAb] is increased irt Egf (15 min)
    *** cells: hESKs<xEgfR> in BMLS "Egf and BPE starved"
    *** source: 15284024-Fig-5a
  *** Stat1[phosAb] phos(Y701)[phosAb] is increased irt Egf (15 min)
    *** cells: hESKs<xEgfR> in BMLS "Egf and BPE starved"
    *** inhibited by: AG490 [addition]
    *** inhibited by: Wortmannin [addition]
    *** unaffected by: LY294002 [addition]
    *** source: 15284024-Fig-2
  *** Stat1[phosAb] phos(Y701)[phosAb] is increased irt Egf (10 min)
    *** cells: A431 in BMS
    *** does not req: Stat3 [RNAi]
    *** source: 17646016-Fig-4
  *** Stat1[phosAb] phos(Y701)[phosAb] is increased irt Egf (10 min)
    *** cells: A431 in BMS
    *** inhibited by: AG1478 [addition]
    *** inhibited by: Compound-56 [addition]
    *** partially inhibited by: CGP77675 [addition]
    *** source: 17646016-Fig-3b
  *** Stat1[phosAb] phos(Y701)[phosAb] is increased irt Egf (10 min)
    *** cells: A431 in BMS
    *** source: 17646016-Fig-1b
  *** Stat1[phosAb] phos(Y701)[phosAb] is increased irt Egf (10 min)
    *** cells: A4318a in BMS
    *** source: 17646016-Fig-1b
  -------------------------------------------------------------------
  *** Stat1[phosAb] phos(Y701)[phosAb] is increased irt Egf (30 min)
    *** cells: HEK293<xEgfR> in BMS
    *** source: 12070153-Fig-1b
  *** Stat1[phosAb] phos(Y701)[phosAb] is increased irt Egf (times)
    *** cells: A431 in BMS "nuclear fraction"
    *** times: 0 30+ 60++ 260+++ 1440 min
    *** source: 12270932-Fig-1a
  *** Stat1[phosAb] phos(Y701)[phosAb] is increased irt Egf (times)
    *** cells: A431 in BMS "nuclear fraction"
    *** times: 0 30+ 180+ 360+ 1440 min
    *** source: 12270932-Fig-2c
  *** Stat1[phosAb] phos(Y701)[phosAb] is increased irt Egf (1 hr)
    *** cells: HN5 in BMS
    *** source: 17918184-Fig-3a
  *** Stat1[phosAb] phos(Y701)[phosAb] is increased irt Egf (times)
    *** cells: A431 in BMS
    *** times: 0 1+ 2+ 4+ 8+ 16+ 24+ hr
    *** source: 17918184-Fig-2a
  *** Stat1[phosAb] phos(Y701)[phosAb] is increased irt Egf (times)
    *** cells: HN5 in BMS
    *** times: 0 1+ 2+ 4+ 8+ 16+ 24+ hr
    *** source: 17918184-Fig-2a

==========
phos(S727)
==========

  *** xStat1[phosAb] phos(S727)[phosAb] is increased irt Egf (15 min)
    *** cells: COS1 in BMS
    *** source: 11278353-Fig-3b
  *** Stat1[phosAb] phos(S727)[phosAb] is increased irt Egf (15 min)
    *** cells: hESKs<xEgfR> in BMLS "Egf and BPE starved"
    *** unaffected by: AG490 [addition]
    *** inhibited by: Wortmannin [addition]
    *** inhibited by: LY294002 [addition]
    *** source: 15284024-Fig-2
  *** Stat1[phosAb] phos(S727)[phosAb] is increased irt Egf (times)
    *** cells: A431 in BMS "nuclear fraction"
    *** times: 0 30+ 60++ 360++ 1440+ hr
    *** source: 12270932-Fig-1a
  *** Stat1[phosAb] phos(Y727)[phosAb] is increased irt Egf (10 min)
    *** cells: A431 in BMS
    *** does not req: Stat3 [RNAi]
    *** source: 17646016-Fig-4

======
coppts
======

Jak1

  *** Stat1[Ab] copptby[WB] Jak1[Ab] is increased irt Egf (15 min)
    *** cells: hESKs<xEgfR> in BMLS "Egf and BPE starved"
    *** source: 15284024-Fig-5b

Jak2

  *** Stat1[Ab] copptby[WB] Jak2[Ab] is increased irt Egf (15 min)
    *** cells: hESKs<xEgfR> in BMLS "Egf and BPE starved"
    *** source: 15284024-Fig-5b
  *** Stat1[Ab] copptby[WB] Jak2[Ab] is increased irt Egf (15 min)
    *** cells: hESKs in BMLS "Egf and BPE starved"
    *** source: 15284024-Fig-5b

Shp2

  *** Stat1[Ab] copptby[WB] Shp2[Ab] is increased irt Egf (tnr)
    *** cells: A431 in BMS
    *** source: 12270932-Fig-1d

Src

  *** Stat1[Ab] copptby[WB] Src[Ab] is increased irt Egf (times)
    *** cells: A431 in BMLS
    *** times: 0 5+ 15+ 30+ 60+ 120+ min
    *** source: 10358079-Fig-5b

===========
CBS binding
===========

  *** Stat1[RE] oligo-binding[EMSA] is increased irt Egf (30 min)
    *** cells: MDAMB468 in BMS
    *** source: 14676838-Fig-3a
  *** Stat1[Ab] snaggedby[WB] oligo[biotin] is increased irt Egf (15 min)
    *** cells: A431 in BMS
    *** source: 17918184-Fig-2b
  *** Stat1[Ab] snaggedby[WB] oligo[biotin] is increased irt Egf (15 min)
    *** cells: HN5 in BMS
    *** source: 17918184-Fig-2b
  *** Stat1[Ab] oligo-binding[EMSA] is increased irt Egf (15 min)
    *** cells: A431 in BMLS
    *** source: 8140422-Fig-3b


==============================
Direct phosphorylation by EgfR
==============================

  *** pStat1[32P] phos[32P-ATP] is increased by pEgfR
    *** cells: none
    *** comment: Stat1 from kinase reaction binds to a GAS oligo
    *** source: 7657660-Fig-5b,6a
  *** pStat1[pYAb] Yphos[pYAb] is increased by pEgfR
    *** cells: none
    *** source: 7657660-Fig-6b
