=============
Transcription
=============

not Cdkn2b--

  *** Myc-gene mRNA[Northern] is decreased irt Tgfb1 (1 hr)
    *** cells: MV1LU in BMS
    *** unaffected by: xCdkn2b [addition]
    *** source: 12150994-Fig-6f

E2f4-- and/or E2f5--  ????

  *** Myc-gene mRNA[Northern] is decreased irt Tgfb1 (2 hr)
    *** cells: HACAT in BMS
    *** does not req: E2f4 [RNAi]
    *** partially reqs: E2f5 [RNAi]
    *** reqs: E2f4 and/or E2f5 [RNAi]
    *** source: 12150994-Fig-7c

not Ppm1a--

  *** Myc-gene mRNA[RTPCR] is decreased irt Tgfb1 (times)
    *** cells: HACAT in BMS
    *** times: 0+++ 4++ 8+ 24+ hr
    *** does not req: Ppm1a [RNAi]
    *** source: 16751101-Fig-5g

Smad3--  ???

  *** Myc-gene mRNA[RPA] is decreased irt Tgfb1 (1 hr)
    *** cells: mSECs in BMS
    *** partially reqs: Smad3 [KO]
    *** source: 14993291-Fig-2a

chemicals

  *** Myc-gene mRNA[Northern] is decreased irt Tgfb1 (1 hr)
    *** cells: HACAT in BMS
    *** enhanced by: CHX [addition]
    *** source: 12150994-Fig-6d

no extras

  *** Myc-gene mRNA[Northern] is decreased irt Tgfb1 (times)
    *** cells: HACAT in BMS
    *** times: 0+ 1 2 4 8 hr
    *** source: 12150994-Fig-6e
  *** Myc-gene mRNA[RPA] is decreased irt Tgfb1 (1 hr)
    *** cells: BALBMK in BMS
    *** source: 14993291-Fig-2a
  *** Myc-gene mRNA[RPA] is decreased irt Tgfb1 (1 hr)
    *** cells: BALBMK in BMS
    *** source: 14993291-Fig-3a
  *** Myc-gene mRNA[RPA] is decreased irt Tgfb1 (times)
    *** cells: HACAT in BMS
    *** times: 0++ 2+ 4+ 8++ hr
    *** source: 14993291-Fig-2c

===========
Translation
===========

not Smad2--

  *** Myc[Ab] prot-exp[WB] is decreased irt Tgfb1 (18 hr)
    *** cells: HACAT in BMLS "treated with serum at 0 hr"
    *** does not req: Smad2 [AntiSense]
    *** source: 14555988-Fig-4a
  *** Myc[Ab] prot-exp[WB] is decreased irt Tgfb1 (18 hr)
    *** cells: MCF10A in BMS
    *** reqs: Smad2 [AntiSense]
    *** source: 14555988-Fig-6a

Smad4--

  *** Myc[Ab] prot-exp[WB] is decreased irt Tgfb1 (18 hr)
    *** cells: HACAT in BMLS "treated with serum at 0 hr"
    *** partially reqs: Smad4 [AntiSense]
    *** source: 14555988-Fig-4b
  *** Myc[Ab] prot-exp[WB] is decreased irt Tgfb1 (18 hr)
    *** cells: MCF10A in BMS
    *** reqs: Smad4 [AntiSense]
    *** source: 14555988-Fig-6c

Smad3--

  *** Myc[Ab] prot-exp[WB] is decreased irt Tgfb1 (18 hr)
    *** cells: HACAT in BMLS "treated with serum at 0 hr"
    *** reqs: Smad3 [AntiSense]
    *** source: 14555988-Fig-4b
  *** Myc[Ab] prot-exp[WB] is decreased irt Tgfb1 (18 hr)
    *** cells: MCF10A in BMS
    *** reqs: Smad3 [AntiSense]
    *** source: 14555988-Fig-6b

no extras

  *** Myc[Ab] prot-exp[WB] is decreased irt Tgfb1 (times)
    *** cells: HACAT in BMS
    *** times: 0+++ 1++ 2+ hr
    *** reversed by: xCsnk1g2 [addition]
    *** repressed by: Csnk1g2 [RNAi]
    *** source: 18794808-Fig-3b






----------- contradictions ---------------------------------

  *** Myc[Ab] prot-exp[WB] is increased irt Tgfb1 (times)
    *** cells: HACAT in BMS
    *** times: 0+ 30++ 120++ 360++ 720++ min
    *** reqs: Smad7 [RNAi]
    *** source: 15684397-Fig-2b
  *** Myc[Ab] prot-exp[WB] is increased irt Tgfb1 (times)
    *** cells: PC3U in BMS
    *** times: 0+ 2+ 6++ 12++ hr
    *** inhibited by: CHX [addition]
    *** source: 15684397-Fig-1e
  *** Myc[Ab] prot-exp[WB] is increased irt Tgfb1 (times)
    *** cells: PC3U in BMS
    *** times: 0+ 2+ 6++ 12+++ hr
    *** reqs: Smad7 [RNAi]
    *** source: 15684397-Fig-1d
  *** Myc[Ab] prot-exp[WB] is increased irt Tgfb1 (times)
    *** cells: PC3U in BMS
    *** times: 0+ 30++ 120++ 360++ 720++ min
    *** reqs: Smad7 [RNAi]
    *** source: 15684397-Fig-2b












