=============
Transcription
=============

Fak1-- phos(Y397) phos(Y925)

  *** Col1a1-gene mRNA[RTPCR] is increased irt Tgfb1 (8 hr)
    *** cells: hMesangialCells in BMLS
    *** source: 18032789-Fig-3a
  *** Col1a1-gene promo-reporter[Luc] is increased irt Tgfb1 (tnr)
    *** cells: hMesangialCells<xFak1> in BMLS
    *** inhibited by: xFak1(Y397F) [substitution]
    *** partially inhibited by: xFak1(Y925F) [substitution]
    *** source: 18032789-Fig-6b


partially inhibited by Smad2--

  *** Col1a1-gene mRNA[RTPCR] is increased irt Tgfb1 (3 hr)
    *** cells: mTECs in BMS
    *** partially inhibited by: xSmad2 [addition]
    *** source: 20595680-Fig-10c
  *** Col1a1-gene mRNA[RTPCR] is increased irt Tgfb1 (3 hr)
    *** cells: mTECs in BMS
    *** repressed by: Smad2 [RNAi]
    *** source: 20595680-Fig-4c
  *** Col1a1-gene mRNA[RTPCR] is increased irt Tgfb1 (3 hr)
    *** cells: mEFs<Smad2~null> in BMS
    *** source: 20595680-Fig-4b
  *** Col1a1-gene mRNA[RTPCR] is increased irt Tgfb1 (times)
    *** cells: mEFs<Smad2~null> in BMS
    *** times: 0 1+ 3++ 6+++ 12++ 24++ hr
    *** source: 20595680-Fig-4a

no extras

  *** Col1a1-gene mRNA[RTPCR] is increased irt Tgfb1 (3 hr)
    *** cells: mEFs in BMS
    *** source: 20595680-Fig-4b
  *** Col1a1-gene mRNA[RTPCR] is increased irt Tgfb1 (times)
    *** cells: mEFs in BMS
    *** times: 0 1+ 3+ 6++ 12+++ 24+++ hr
    *** source: 20595680-Fig-4a

==============
Promo-Reporter
==============

  *** Col1a1-gene promo-reporter[Luc] is increased irt Tgfb1 (24 hr)
    *** cells: AKR2B in BMLS
    *** enhanced by: Rapamycin [pretreatment]
    *** source: 19117990-Fig-3d
  *** Col1a1-gene promo-reporter[Luc] is increased irt Tgfb1 (24 hr)
    *** cells: AKR2B in BMLS
    *** partially reqs: Raptor [RNAi]
    *** partially reqs: Rictor [RNAi]
    *** source: 19117990-Fig-6c

===========
Translation
===========

  *** Col1[Ab] prot-exp[WB] is increased irt Tgfb1 (24 hr)
    *** cells: mEFs in BMS
    *** repressed by: Smad2 [KO]
    *** source: 20595680-Fig-5b
  *** Col1[Ab] prot-exp[WB] is increased irt Tgfb1 (times)
    *** cells: mEFs in BMS
    *** times: 0 6+ 12++ 24+++ hr
    *** source: 20595680-Fig-5a
  *** Col1[Ab] prot-exp[WB] is increased irt Tgfb1 (times)
    *** cells: mEFs<Smad2~null> in BMS
    *** times: 0 6+ 12++ 24+++ hr
    *** source: 20595680-Fig-5a

  *** Col1a1[Ab] prot-exp[WB] is increased irt Tgfb1 (24 hr)
    *** cells: AKR2B in BMLS
    *** unaffected by: Rapamycin [pretreatment]
    *** source: 19117990-Fig-3d

