=============
Pxn phos(Y31)
=============

Ptk6--

  *** Pxn[Ab]IP phos(Y31)[phosAb] is increased irt Egf (15 min)
    *** cells: COS1 in BMLS
    *** inhibited by: xPtk6(K219M)"KD" [addition]
    *** source: 15572663-Fig-5e
  --------------------------------------------------------------
  *** Pxn[phosAb] phos(Y31)[phosAb] is unchanged irt Egf (5 min)
    *** cells: mEFs<Shp2~null><xShp2> in BMLS
    *** source: 14967142-Fig-5a

==============
Pxn phos(Y118)
==============

Ptk6--

  *** Pxn[Ab]IP phos(Y118)[phosAb] is increased irt Egf (15 min)
    *** cells: COS1 in BMLS
    *** inhibited by: xPtk6(K219M)"KD" [addition]
    *** source: 15572663-Fig-5e
  --------------------------------------------------------------
  *** Pxn[phosAb] phos(Y118)[phosAb] is unchanged irt Egf (5 min)
    *** cells: mEFs<Shp2~null><xShp2> in BMLS
    *** source: 14967142-Fig-5a

============================
Phoshphorylation on Tyrosine
============================

Ptk6--

  *** Pxn[Ab]IP Yphos[pYAb] is increased irt Egf (15 min)
    *** cells: COS1 in BMLS "on Fibronectin"
    *** inhibited by: xPtk6(K219M)"KD" [addition]
    *** source: 15572663-Fig-5d

  *** Pxn[Ab]IP Yphos[pYAb] is increased irt Egf (times)
    *** cells: COS1 in BMLS "on Fibronectin"
    *** times: 0 5+ 15++ 30 60 min
    *** source: 15572663-Fig-5c
  --------------------------------------------------------------
  *** Pxn[Ab]IP Yphos[pYAb] is decreased irt Egf (times)
    *** cells: RAT1<xInsR> in BMLS
    *** times: 0++ 1+ 5+ 10+ 20+ min
    *** source: 9348226-Fig-2a
  *** Pxn[Ab]IP Yphos[pYAb] is decreased irt Egf (10 min)
    *** cells: MDAMB468 in BMLS
    *** inhibited by: xShp2(C459S/D425A)"CIA" [addition]
    *** source: 14665621-Fig-5b
  *** Pxn[Ab]IP Yphos[pYAb] is decreased irt Egf (10 min)
    *** cells: MDAMB468 in BMLS
    *** source: 14665621-Fig-4b
  *** Pxn[Ab]IP Yphos[pYAb] is decreased irt Egf (times)
    *** cells: A431 in BMLS
    *** times: 0++ 2++ 5+ 10+ 15+ 30+ min
    *** source: 14665621-Fig-1b
  *** Pxn[Ab]IP Yphos[pYAb] is decreased irt Egf (times)
    *** cells: MDAMB468 in BMLS
    *** times: 0+++ 2++ 5+ 10 15 30+ min
    *** source: 14665621-Fig-1a

=====================
Total Phosphorylation
=====================

  *** xPxn[Ab]IP phos[32Pi] is increased irt Egf (times)
    *** cells: MDAMB231 in BMS
    *** times: 0 7+ 15++ 25++ min
    *** source: 12858963-Fig-3d

==================================
coppt with other proteins in EgfRC
==================================

  *** Pxn[Ab] copptby[WB] Crk[Ab] is increased irt Egf (times)
    *** cells: RAT1<xInsR> in BMLS
    *** times: 0 1+ 5++ 10++ 20++ min
    *** source: 9348226-Fig-2b

  *** Pxn[Ab] copptby[WB] Gab1[Ab] is increased irt Egf (times)
    *** cells: MDAMB468 in BMLS
    *** times: 0+ 5++ 10++ 30++ min
    *** source: 14665621-Fig-2a
  *** Pxn[Ab] copptby[WB] xGab1(Y627F/Y659F)[tAb] is increased irt Egf (10 min)
    *** cells: MDAMB468 in BMLS
    *** source: 14665621-Fig-4c

=========================
Location by Fractionation
=========================

  *** Pxn[Ab] infraction(membrane)[WB] is decreased irt Egf (16 hr)
    *** cells: NIH3T3 in BMS
    *** comment: no total protein controls
    *** source: 20375009-Fig-S4


