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Transcription
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Ctdsp1--  Ctdsp2--  ???

  *** Cdkn2b-gene promo-reporter[Luc] is increased irt Tgfb1 (tnr)
    *** cells: HACAT in BMS
    *** bkg enhanced by: xCtdsp1 [addition]
    *** unaffected by: xCtdsp1(D96E/D98N)"CIA" [addition]
    *** source: 17035229-Fig-6a
  *** Cdkn2b-gene mRNA[RTPCR] is increased irt Tgfb1 (3 hr)
    *** cells: OSACL in BMS
    *** reqs: Ctdsp1 and/or Ctdsp2 [RNAi]
    *** source: 17085434-Fig-6c

inhibited by Pias4--

  *** Cdkn2b-gene mRNA[Northern] is increased irt Tgfb1 (times)
    *** cells: MV1LU in BMS
    *** times: 0 1+ 2+ 4++ 8++ hr
    *** partially inhibited by: xPias4 [addition]
    *** source: 12904571-Fig-3

inhibited by Ppm1a--

  *** Cdkn2b-gene promo-reporter[Luc] is increased irt Tgfb1 (tnr)
    *** cells: HACAT in BMS
    *** repressed by: Ppm1a [RNAi]
    *** source: 16751101-Fig-5i
  *** Cdkn2b-gene mRNA[RTPCR] is increased irt Tgfb1 (times)
    *** cells: HACAT in BMS
    *** times: 0 4+ 8+ 24+ hr
    *** repressed by: Ppm1a [RNAi]
    *** source: 16751101-Fig-5b

Smad3--

  *** Cdkn2b-gene promo-reporter[Luc] is increased irt Tgfb1 (tnr)
    *** cells: mEFs<Smad3~null><xSmad3> in BMS
    *** unaffected by: xSmad3(T8V) [substitution]
    *** enhanced by: xSmad3(T179V) [substitution]
    *** enhanced by: xSmad3(S213A) [substitution]
    *** enhanced by: xSmad3(T8V/T179V/S213A) [substitution]
    *** source: 15241418-Fig-3a
  *** Cdkn2b-gene promo-reporter[Luc] is increased irt Tgfb1 (12 hr)
    *** cells: RGM1<xSmad3> in BMLS
    *** unaffected by: xSmad3(T179V/S204A/S208A/S213A) [substitution]
    *** bkg inhibited by: xSmad3(S416A/S422A/S425A) [substitution]
    *** source: 15326485-Fig-9a
  *** Cdkn2b-gene mRNA[Northern] is increased irt Tgfb1 (24 hr)
    *** cells: mEFs<Smad3~null><xSmad3> in BMS
    *** source: 15241418-Fig-4e

no extras--

  *** Cdkn2b-gene mRNA[Northern] is increased irt Tgfb1 (times)
    *** cells: HACAT in BMS
    *** times: 0 1 2+ 4+ 8+ hr
    *** source: 12150994-Fig-6e
  *** Cdkn2b-gene promo-reporter[Luc] is increased irt Tgfb1 (tnr)
    *** cells: HACAT in BMS
    *** source: 16751101-Fig-5c
  *** Cdkn2b-gene promo-reporter[Luc] is increased irt Tgfb1 (tnr)
    *** cells: HEPG2 in BMS
    *** source: 15241418-Fig-3c
  *** Cdkn2b-gene promo-reporter[Luc] is increased irt Tgfb1 (12 hr)
    *** cells: RGM1 in BMLS
    *** source: 15326485-Fig-9a

===========
Translation
===========

  *** Cdkn2b[Ab] prot-exp[WB] is increased irt Tgfb1 (18 hr)
    *** cells: HACAT in BMLS "treated with serum at 0 hr"
    *** does not req: Smad2 [AntiSense]
    *** source: 14555988-Fig-4a
  *** Cdkn2b[Ab] prot-exp[WB] is increased irt Tgfb1 (18 hr)
    *** cells: HACAT in BMLS "treated with serum at 0 hr"
    *** does not req: Smad3 [AntiSense]
    *** source: 14555988-Fig-4b
  *** Cdkn2b[Ab] prot-exp[WB] is increased irt Tgfb1 (18 hr)
    *** cells: HACAT in BMLS "treated with serum at 0 hr"
    *** partially reqs: Smad4 [AntiSense]
    *** source: 14555988-Fig-4b
  *** Cdkn2b[Ab] prot-exp[WB] is increased irt Tgfb1 (20 hr)
    *** cells: HACAT in BMS
    *** unaffected by: xCtdsp1 [addition]
    *** source: 17035229-Fig-7d
  *** Cdkn2b[Ab] prot-exp[WB] is increased irt Tgfb1 (24 hr)
    *** cells: mEFs in BMS
    *** reqs: Pml [KO]
    *** source: 15356634-Fig-1c
