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Coprecipitation
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Axin1 required features

  *** Mekk1[Ab] copptby[WB] Axin1[Ab] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xAxin1(del(679-711))"M8" [addition]
    *** source: 12878610-Fig-3
  *** Axin1[Ab] copptby[WB] Mekk1[Ab] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xAxin1(del(210-338))"D19" [addition]
    *** source: 12878610-Fig-3
  *** xAxin1[tAb] copptby[WB] xMekk1(mnr)"C"[tAb] is detectable
    *** cells: HEK293T<xAxin1><xMekk1> in BMS
    *** unaffected by: xAxin1(198-832)"N1" [substitution]
    *** inhibited by: xAxin1(400-832)"N2" [substitution]
    *** inhibited by: xAxin1(509-832)"N3" [substitution]
    *** unaffected by: xAxin1(1-746)"C2" [substitution]
    *** unaffected by: xAxin1(1-398)"C3" [substitution]
    *** inhibited by: xAxin1(1-230)"C4" [substitution]
    *** unaffected by: xAxin1(198-398)"M4" [substitution]
    *** unaffected by: xAxin1((198-353)/(509-832))"M3" [substitution]
    *** source: 10575011-Fig-4
  *** xMekk1(mnr)"C"[tAb] copptby[WB] xAxin1[tAb] is detectable
    *** cells: HEK293T<xAxin1><xMekk1> in BMS
    *** unaffected by: xAxin1(198-832)"N1" [substitution]
    *** inhibited by: xAxin1(400-832)"N2" [substitution]
    *** inhibited by: xAxin1(509-832)"N3" [substitution]
    *** unaffected by: xAxin1(1-746)"C2" [substitution]
    *** unaffected by: xAxin1(1-398)"C3" [substitution]
    *** inhibited by: xAxin1(1-230)"C4" [substitution]
    *** unaffected by: xAxin1(198-398)"M4" [substitution]
    *** unaffected by: xAxin1((198-353)/(509-832))"M3" [substitution]
    *** source: 10575011-Fig-4

Mekk1 required features

  *** xAxin1[tAb] copptby[WB] xMekk1[tAb] is detectable
    *** cells: HEK293T<xAxin1><xMekk1> in BMS
    *** inhibited by: xMekk1(mnr)"N3.1" [substitution]
    *** inhibited by: xMekk1(mnr)"N1.9" [substitution]
    *** unaffected by: xMekk1(mnr)"C" [substitution]
    *** source: 10575011-Fig-2c
  *** xMekk1[tAb] copptby[WB] xAxin1[tAb] is detectable
    *** cells: HEK293T<xAxin1><xMekk1> in BMS
    *** inhibited by: xMekk1(mnr)"N3.1" [substitution]
    *** inhibited by: xMekk1(mnr)"N1.9" [substitution]
    *** unaffected by: xMekk1(mnr)"C" [substitution]
    *** source: 10575011-Fig-2c

No extras

  *** xAxin1[tAb] copptby[WB] xMekk1(mnr)"C"[tAb] is detectable
    *** cells: HEK293T<xAxin1><xMekk1(mnr)"C"> in BMS
    *** source: 11884395-Fig-2a
  *** xAxin1[tAb] copptby[WB] xMekk1(mnr)"C"[tAb] is detectable
    *** cells: HEK293T<xAxin1><xMekk1(mnr)"C"> in BMS
    *** source: 11884395-Fig-2b


