=====================================
Proteins Required for mRNA expression
=====================================

Irak4--

  *** CxcL1-gene mRNA[RTPCR] is increased irt IL1b (times)
    *** cells: mEFs in BMS
    *** times: 0 1+ 2+ 4+ 6+ hr
    *** partially inhibited by: kIrak4(K213A/K214A)"KD" [knockin]
    *** source: 17337443-Fig-5b


===============================
Proteins Required for secretion
===============================

  *** CxcL1[Ab] secretion[ELISA] is increased irt IL1b (24 hr)
    *** cells: mBMMs in BMS
    *** inhibited by: kIrak4(K213A/K214A)"KD" [knockin]
    *** source: 17470642-Fig-3b
  *** CxcL1[Ab] secretion[ELISA] is increased irt IL1b (times)
    *** cells: mEFs in BMS
    *** times: 0 16+ 24++ 40+++ hr
    *** inhibited by: kIrak4(K213A/K214A)"KD" [knockin]
    *** source: 17337443-Fig-6a
  *** CxcL1[Ab] secretion[ELISA] is increased irt IL1 (tnr)
    *** cells: mEFs<Tirap~null><Myd88~null><xMyd88> in BMS
    *** source: 16751103-Fig-6h

