===========================
P38a Direct Phosphorylation
===========================

  *** rP38a[32P] phos[32P-ATP] is increased by rMkk3
    *** cells: none
    *** inhibited by: rP38a(T180A/Y182F) [substitution]
    *** source: 7839144-Fig-2a
  *** rP38a[32P] phos[32P-ATP] is increased by rMkk3
    *** cells: none
    *** source: 7839144-Fig-2a
  *** rP38a[32P] phos[32P-ATP] is increased by rMkk3
    *** cells: none
    *** source: 9430721-Fig-7a
  *** rP38a[32P] phos[32P-ATP] is increased by (rMkk3 + rTaok1(1-416)"CA")
    *** cells: none
    *** reqs: both [omissions]
    *** source: 9786855-Fig-4a
  *** rP38a[32P] phos[32P-ATP] is increased by (rMkk3 + rTaok1(1-416)"CA")
    *** cells: none
    *** reqs: both [omissions]
    *** source: 10497253-Fig-2a

===============
P38a Activation
===============

  *** xP38a[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xMkk3
    *** cells: COS7 in BMS
    *** source: 8663524-Fig-7
  *** xP38a[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xMkk3(S218E/T222E)"CA"
    *** cells: COS7 in BMS
    *** source: 9430721-Fig-6a
  *** xP38a[Ab]IP IVKA(Atf2)[32P-ATP] is increased itpo xMkk3
    *** cells: COS1 in BMS
    *** source: 7839144-Fig-5
  *** xP38a[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xMkk3(S189E/T193E)
    *** cells: COS1 in BMS
    *** inhibited by: xMkk3(S189A/T193A) [substitution]
    *** source: 8622669-Fig-1b
  *** xP38a[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xMkk3(S189E/T193E)
    *** cells: COS1 in BMS
    *** inhibited by: xP38a(T180A/Y182F) [substitution]
    *** source: 8622669-Fig-1b
  *** xP38a[Ab]IP IVKA(Atf2)[32P-ATP] is increased itpo xMkk3(S189E/T193E)
    *** cells: COS1 in BMS
    *** source: 8622669-Fig-7c
  *** P38a[Ab]IP IVKA(Atf2)[32P-ATP] is unchanged itpo xMkk3(S189E/T193E)
    *** cells: COS1 in BMS
    *** comment: experimental conditions optimal for xP38a not endogenous P38a
    *** source: 8622669-Fig-7c
  *** xP38a[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xMkk3(S189E/T193E)
    *** cells: COS1 in BMS
    *** source: 8622669-Fig-2a


  --------------------------------------------------------------------------
  *** xP38b[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xMkk3
    *** cells: COS7 in BMS
    *** source: 8663524-Fig-7
  *** xP38b[tAb]IP IVKA(Atf2)[32P-ATP] is unchanged itpo xMkk3(S218E/T222E)"CA"
    *** cells: COS7 in BMS
    *** source: 9430721-Fig-6a
  *** rP38b[32P] phos[32P-ATP] is unchanged by rMkk3
    *** cells: none
    *** source: 9430721-Fig-7a
  --------------------------------------------------------------------------
  *** rP38g[32P] phos[32P-ATP] is increased by rMkk3
    *** cells: none
    *** source: 9430721-Fig-7a
  --------------------------------------------------------------------------
  *** xP38g[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xMkk3(S218E/T222E)"CA"
    *** cells: COS7 in BMS
    *** source: 9430721-Fig-6a
  *** xP38a[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xMkk3(mnr)"CA"
    *** cells: HEK293T in BMS
    *** inhibited by: SB203580 [addition]
    *** source: 12972619-Fig-2f

