=================
Required Proteins
=================

IL2Rb--

  *** Jnks[Ab]IP IVKA(Atf2)[32P-ATP] is increased irt IL2 (10 min)
    *** cells: BAFB03<xIL2Rb(1-355)> in BMS "IL3-deprived"
    *** inhibited by: xIL2Rb(Y338F) [substitution]
    *** inhibited by: xIL2Rb((1-355)/Y338F) [substitution]
    *** enhanced by: xIL2Rb(1-325)"Shc1-fusion" [substitution]
    *** source: 1066828-Fig-3a
  *** Jnks[Ab]IP IVKA(Atf2)[32P-ATP] is increased irt IL2 (10 min)
    *** cells: BAFB03<xIL2Rb> in BMS "IL3-deprived"
    *** inhibited by: xIL2Rb(del(266-323)) [substitution]
    *** inhibited by: xIL2Rb(del(312-383)) [substitution]
    *** source: 1066828-Fig-2b
  *** Jnks[Ab]IP IVKA(Atf2)[32P-ATP] is increased irt IL2 (10 min)
    *** cells: BAFB03<xIL2Rb> in BMS "IL3-deprived"
    *** unaffected by: xIL2Rb(del(266-323)) [substitution]
    *** unaffected by: xIL2Rb(del(312-383)) [substitution]
    *** source: 1066828-Fig-2b
  *** Jnks[phosAb] phos(TPY)[phosAb] is increased irt IL2 (10 min)
    *** cells: BAFB03<xIL2Rb(1-355)> in BMS "IL3-deprived"
    *** inhibited by: xIL2Rb(Y338F) [substitution]
    *** inhibited by: xIL2Rb((1-355)/Y338F) [substitution]
    *** enhanced by: xIL2Rb(1-325)"Shc1-fusion" [substitution]
    *** source: 1066828-Fig-3a

=========
Chemicals
=========

CNI1493--

  *** Jnks[Ab]IP IVKA(Atf2)[32P-ATP] is increased irt IL2 (10 min)
    *** cells: BAFB03<xIL2Rb> in BMS "IL3-deprived"
    *** inhibited by: CNI1493 [pretreatment]
    *** source: 1066828-Fig-5
  *** Jnks[Ab]IP IVKA(Atf2)[32P-ATP] is increased irt IL2 (10 min)
    *** cells: CT6 in BMS "IL2-deprived"
    *** inhibited by: CNI1493 [pretreatment]
    *** source: 1066828-Fig-5

SB203580--

  *** Jnks[Ab]IP IVKA(Atf2)[32P-ATP] is increased irt IL2 (10 min)
    *** cells: CT6 in BMS
    *** unaffected by: SB203580 [pretreatment]
    *** source: 9169478-Fig-4d

=========
No Extras
=========

  *** Jnks[Ab]IP IVKA(Atf2)[32P-ATP] is increased irt IL2 (10 min)
    *** cells: CT6 in BMS
    *** source: 9169478-Fig-1b
  *** Jnks[Ab]IP IVKA(Atf2)[32P-ATP] is increased irt IL2 (10 min)
    *** cells: CT6 in BMS
    *** source: 9169478-Fig-1c
  *** Jnks[Ab]IP IVKA(Atf2)[32P-ATP] is increased irt IL2 (times)
    *** cells: KIT225 in BMS
    *** times: 0 10+ 20+ 30+ min
    *** source: 9169478-Fig-1a

==============
Contradictions
==============

  *** Jnks[phosAb] phos(TPY)[phosAb] is unchanged irt IL2 (15 min)
    *** cells: hPBTCs<Itgb2~neg><Cd8~pos><Cd56~neg><Cd4~neg><Cd20~neg> in BMS
    *** unaffected by: IL12 [cotreatment]
    *** source: 10201984-Fig-2a
