==============================================
Proteins required for Ikba degradation irt Tnf
==============================================

not Atm--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (2 hr)
    *** cells: HEK293 in BMS
    *** does not req: Atm [RNAi]
    *** source: 14651848-Fig-6a

not Atr--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (2 hr)
    *** cells: HEK293 in BMS
    *** does not req: Atr [RNAi]
    *** source: 14651848-Fig-6a

not Azi2--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: HELA in BMS
    *** times: 0+ 10 30 min
    *** does not req: Azi2 [RNAi]
    *** source: 14560022-Fig-7c

not Bcl10--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (30 min)
    *** cells: mEFs in BMS "treated with CHX"
    *** does not req: Bcl10 [KO]
    *** source: 17095601-Fig-1b

Ciap1-- and/or Ciap2--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0++ 5+ 30 min
    *** reqs: Ciap1 [KO]
    *** source: 18621737-Fig-1a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs<Ciap2~null> in BMS
    *** times: 0++ 5+ 30 min
    *** reqs: Ciap1 [RNAi]
    *** source: 18621737-Fig-1b
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: C2C12 in BMS
    *** times: 0+++ 5++ 15+ 30+ 60+++ min
    *** reqs: Ciap1 [RNAi]
    *** source: 18697935-Fig-2a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: C2C12 in BMS
    *** times: 0+++ 5++ 15+ min
    *** does not req: Ciap2 [RNAi]
    *** partially reqs: Ciap1 [RNAi]
    *** reqs: Ciap1 and/or Ciap2 [RNAi]
    *** source: 18697935-Fig-S3b
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: C2C12 in BMS
    *** times: 0+++ 5++ 15+ min
    *** reqs: Ciap1 [RNAi]
    *** source: 18697935-Fig-3c
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: C2C12<xCiap1(mnr)"KD"><xCiap2> in BMS
    *** times: 0+++ 5++ 15+ min
    *** reqs: xCiap2 [omission]
    *** source: 18697935-Fig-3c
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0++ 5+ 15 min
    *** does not req: Ciap1 [RNAi]
    *** does not req: Ciap2 [RNAi]
    *** reqs: Ciap1 and/or Ciap2 [RNAi]
    *** source: 18697935-Fig-3a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs<Ciap1~null> in BMS
    *** times: 0+++ 5++ 15+ min
    *** reqs: Ciap2 [RNAi]
    *** source: 18697935-Fig-4b
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs<Ciap1~null> in BMS
    *** times: 0+++ 5++ 15+ min
    *** reqs: Ciap2 [RNAi]
    *** source: 18697935-Fig-S3a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs<Ciap1~null><xCiap2> in BMS
    *** times: 0+++ 5++ 15+ min
    *** reversed by: xCiap2(H588A) [substitution]
    *** source: 18697935-Fig-4b
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mHepatocytes in BMS
    *** times: 0+++ 5++ 15+ min
    *** partially reqs: Ciap1 [RNAi]
    *** does not req: Ciap2 [RNAi]
    *** reqs: Ciap1 and/or Ciap2 [RNAi]
    *** source: 18697935-Fig-3b
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mSkMFibros in BMS
    *** times: 0+++ 5++ 15+ min
    *** does not req: Ciap1 [KO]
    *** does not req: Ciap2 [KO]
    *** does not req: Ciap1 and/or Ciap2 [RNAi]
    *** partially reqs: Ciap1 [KO] and/or Ciap2 [RNAi]
    *** partially reqs: Ciap1 [RNAi] and/or Ciap2 [KO]
    *** source: 18697935-Fig-S4
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mSkMs in BMS
    *** times: 0++ 5+ 15 60++ min
    *** does not req: Ciap2 [KO]
    *** source: 18697935-Fig-2d
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mSkMs in BMS
    *** times: 0++ 5+ 15 60++ min
    *** partially reqs: Ciap1 [KO]
    *** source: 18697935-Fig-2d
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0++ 5+ 30 min
    *** does not req: Ciap2 [KO]
    *** source: 18621737-Fig-1a

not Xiap--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0++ 5+ 30 min
    *** does not req: Xiap [KO]
    *** source: 18621737-Fig-1a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: C2C12 in BMS
    *** times: 0+++ 5++ 15+ 30++ 60+++ min
    *** does not req: Xiap [RNAi]
    *** source: 18697935-Fig-S2
  *** Ikba[Ab] prot-exp[WB] is unchanged irt Tnf (times)
    *** cells: C2C12<xCiap1(mnr)"KD"> in BMS
    *** times: 0+++ 5++ 15+ min
    *** unaffected by: xXiap [addition]
    *** source: 18697935-Fig-3c

Btrc--

  *** xIkba[tAb] prot-exp[WB] is decreased irt Tnf (30 min)
    *** cells: HEK293 in BMS
    *** reversed by: xBtrc(mnr)"F-box-deletion-mutant" [addition]
    *** comment: the addition of xBtrc-mut has less effect on endogenous Ikba
    *** source: 9990853-Fig-2
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: HEK293 in BMS "cytoplasmic-extracts from cells treated with CHX"
    *** times: 0++ 15+ 30 min
    *** enhanced by: xBtrc [addition]
    *** reversed by: xBtrc(del(148-192)) [addition]
    *** source: 10075690-Fig-2a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (15 min)
    *** cells: HELA in BMS
    *** reqs: Fbxw11 and/or Btrc [RNAi]
    *** source: 12482991-Fig-6b

reversed by Cezanne--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: HEK293 in BMS
    *** times: 0+++ 5++ 15+ 20 min
    *** partially reversed by: xCezanne [addition]
    *** source: 18178551-Fig-4a

reversed by Cyld--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: HEK293T in BMS
    *** times: 0+ 10 20 min
    *** reversed by: xCyld [addition]
    *** source: 12917691-Fig-S4b
  *** xIkba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: HEK293T in BMS
    *** times: 0+ 10 20 min
    *** reversed by: xCyld [addition]
    *** source: 12917691-Fig-S4b

Erc1--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: HELA in BMS
    *** times: 0+ 7+ 15+ 30 60 120+ min
    *** reqs: Erc1 [RNAi]
    *** source: 15218148-Fig-2b

not Gsk3b--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 15 30 60 120+ 240+ 480+ min
    *** does not req: Gsk3b [KO]
    *** source: 10894547-Fig-5h

not Hdac3--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: HELA in BMS
    *** times: 0+ 10 30 90+ min
    *** unaffected by: xHdac3 [addition]
    *** source: 11533489-Fig-3c

not Ikk1--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (15 min)
    *** cells: mEFs in BMS
    *** does not req: Ikk1 [KO]
    *** source: 21765415-Fig-6a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (15 min)
    *** cells: mEFs<xTax1bp1> in BMS
    *** does not req: Ikk1 [KO]
    *** source: 21765415-Fig-1e
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 15 30 60+ min
    *** does not req: Ikk1 [KO]
    *** source: 17244613-Fig-1b
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 15 30 60+ min
    *** does not req: Ikk1 [KO]
    *** source: 11733537-Fig-3a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: HELA in BMS
    *** times: 0+ 2+ 5+ 10 20 60 min
    *** does not req: Ikk1 [RNAi]
    *** source: 12547194-Fig-1a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (10 min)
    *** cells: mEFs in BMS
    *** does not req: Ikk1 [KO]
    *** source: 12759443(D)
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 5 10 30 min
    *** does not req: Ikk1 [KO]
    *** source: 12759443-Fig-2b
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (15 min)
    *** cells: mEFs<Ikk1~null><xIkk1> in BMS
    *** unaffected by: xIkk1(K44M)"KD" [substitution]
    *** source: 21765415-Fig-1g
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (15 min)
    *** cells: mEFs<Ikk1~null><xIkk1><xTax1bp1> in BMS
    *** does not req: xIkk1 [omission]
    *** unaffected by: xIkk1(K44M)"KD" [substitution]
    *** source: 21765415-Fig-1h
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0++ 5+ 15 60++ min
    *** does not req: Ikk1 [KO]
    *** source: 11297557-Fig-1a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0++ 5++ 10+ 20 30+ 60++ min
    *** does not req: Ikk1 [KO]
    *** source: 19666475-Fig-5a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs<Ikk1~null><xIkk1> in BMS
    *** times: 0++ 5+ 10 20 30+ 60++ min
    *** does not req: xIkk1 [omission]
    *** unaffected by: xIkk1(1-737)"delNBD" [substitution]
    *** source: 19666475-Fig-5a


Ikk2--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (15 min)
    *** cells: mEFs in BMS
    *** reqs: Ikk2 [KO]
    *** source: 21765415-Fig-6a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 15 60+ min
    *** reqs: Ikk2 [KO]
    *** source: 17244613-Fig-3b
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 5 10 30 min
    *** reqs: Ikk2 [KO]
    *** source: 12759443-Fig-2b
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 15 30 60+ min
    *** reqs: Ikk2 [KO]
    *** source: 17244613-Fig-1b
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 15 30 60+ min
    *** partially reqs: Ikk2 [KO]
    *** source: 11733537-Fig-3a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: HELA in BMS
    *** times: 0+ 2+ 5+ 10 20 60 min
    *** does not req: Ikk2 [RNAi]
    *** source: 12547194-Fig-1b
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (10 min)
    *** cells: mEFs in BMS
    *** partially reqs: Ikk2 [KO]
    *** source: 12759443(D)
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 15 30+ 60+ min
    *** reversed by: xIkk2(K44M) [addition]
    *** source: 17244613-Fig-4b
  *** Ikba[Ab] prot-exp[WB] is unchanged irt Tnf (times)
    *** cells: mEFs<Ikk1~null><Ikk2~null><xIkk1> in BMS
    *** times: 0+ 15+ 30+ 60+ min
    *** source: 17244613-Fig-5c
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (15 min)
    *** cells: mEFs<xTax1bp1> in BMS
    *** reqs: Ikk2 [KO]
    *** source: 21765415-Fig-1e
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0++ 5+ 15 60++ min
    *** reqs: Ikk2 [KO]
    *** source: 11297557-Fig-1b
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0++ 5++ 10+ 20 30 60++ min
    *** reqs: Ikk2 [KO]
    *** source: 19666475-Fig-1c
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs<Ikk2~null><xIkk2> in BMS
    *** times: 0++ 5+ 10 20 30+ 60++ min
    *** reqs: xIkk2 [omission]
    *** reversed by: xIkk2(1-733)"delNBD" [substitution]
    *** source: 19666475-Fig-1c

Ikk1 and/or Ikk2--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 15 60+ 120+ min
    *** reqs: Ikk1 and/or Ikk2 [DKO]
    *** source: 10898787-Fig-2b
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: HELA in BMS
    *** times: 0+ 2+ 5+ 10 20 60 min
    *** partially reqs: Ikk1 and/or Ikk2 [RNAi]
    *** source: 12547194(D)
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0++ 15 30+ 60++ min
    *** reqs: Ikk1 and/or Ikk2 [DKO]
    *** source: 17244613-Fig-5c

not Irak3--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mBMMs in BMS
    *** times: 0+ 10 20 60+ min
    *** does not req: Irak3 [KO]
    *** source: 12150927-Fig-4c

not Irak4--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 15 30 min
    *** unaffected by: xIrak4(K213A/K214A)"KD" [addition]
    *** source: 17337443-Fig-3c

not Malt1--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (30 min)
    *** cells: mEFs in BMS "treated with CHX"
    *** does not req: Malt1 [KO]
    *** source: 17095601-Fig-1b


not Mekk2--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS "on gelatin"
    *** times: 0+ 15 60 120+ min
    *** does not req: Mekk2 [RNAi]
    *** source: 14636585(D)

Mekk3--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS "on gelatin"
    *** times: 0+ 15 60 120+ min
    *** reqs: Mekk3 [KO]
    *** source: 14636585(D)
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 10 20 30+ 45+ 60+ min
    *** reqs: Mekk3 [KO]
    *** source: 11429546-Fig-3b

not Mlk3--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 5+ 10 15 min
    *** does not req: Mlk3 [KO]
    *** source: 15831472(D)

not Msk1/Msk2--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 5+ 10+ 15 20 30 min
    *** does not req: Msk1 or Msk2 [DKO]
    *** source: 12628924-Fig-8a

Muc1--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: MCF10A in BMS "cytoplasmic fraction"
    *** times: 0+ 30 120 min
    *** reqs: Muc1 [RNAi]
    *** source: 18037881-Fig-4a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (30 min)
    *** cells: MCF10A in BMS "cytoplasmic fraction"
    *** reqs: Muc1 [RNAi]
    *** source: 18037881-Fig-4b
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (30 min)
    *** cells: mMECs in BMS "cytoplasmic fraction"
    *** reqs: Muc1 [RNAi]
    *** source: 18037881-Fig-4c

not Myd88--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs<Myd88~null><xMyd88> in BMS
    *** times: 0+ 2 30 min
    *** does not req: xMyd88 [omission]
    *** source: 12538665-Fig-1b
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 10 30 min
    *** does not req: Myd88 [KO]
    *** source: 16115877-Fig-4a,4b,4c

Nemo--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 15 30 60+ min
    *** reqs: Nemo [KO]
    *** source: 17244613-Fig-1b
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (10 min)
    *** cells: JURKAT<Pten~null> in BMS
    *** reqs: Nemo [KO]
    *** source: 16547522-Fig-3b
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (10 min)
    *** cells: mEFs in BMS
    *** reqs: Nemo [KO]
    *** source: 16547522-Fig-3d
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (20 min)
    *** cells: HEK293T in BMS
    *** reversed by: xNemo [addition]
    *** source: 10755617(D)
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (15 min)
    *** cells: mEFs in BMS
    *** reqs: Nemo [KO]
    *** source: 21765415-Fig-6a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (15 min)
    *** cells: mEFs<xTax1bp1> in BMS
    *** reqs: Nemo [KO]
    *** source: 21765415-Fig-1e
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0++ 5+ 15 60++ min
    *** reqs: Nemo [KO]
    *** source: 11297557-Fig-1c

  requirement for Nemo ubiq sites

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (10 min)
    *** cells: JURKAT<Pten~null><Nemo~null><xNemo> in BMS
    *** reqs: xNemo [omission]
    *** reversed by: xNemo(L320P) [substitution]
    *** reversed by: xNemo(D311N) [substitution]
    *** source: 16547522-Fig-3b
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (10 min)
    *** cells: mEFs<Nemo~null><xNemo> in BMS
    *** reqs: xNemo [omission]
    *** reversed by: xNemo(L320P) [substitution]
    *** reversed by: xNemo(D311N) [substitution]
    *** source: 16547522-Fig-3d

not Nfkb1--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (15 min)
    *** cells: HELA<xNfkb1> in BMS
    *** unaffected by: xNfkb1(S927A) [substitution]
    *** unaffected by: xNfkb1(S932A) [substitution]
    *** source: 12482991-Fig-2c
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: HELA<xNfkb1> in BMS
    *** times: 0+ 15 30 60 min
    *** unaffected by: xNfkb1(S927A) [substitution]
    *** source: 11297557-Fig-4b

not Nik--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (tbg)
    *** cells: mEFs in BMS
    *** does not req: Nik [KO]
    *** source: 11238593(D)
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (30 min)
    *** cells: HEK293<xCd40> in BMS
    *** unaffected by: xNik(del(624-947))"DN" [addition]
    *** source: 12374738-Fig-7b

not Nkiras1/2

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (30 min)
    *** cells: HEK293 in BMS
    *** does not req: Nkiras1 [RNAi]
    *** source: 15024091-Fig-3a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: HELA in BMS
    *** times: 0+ 15 30 min
    *** does not req: Nkiras1 or Nkiras1 [RNAi]
    *** source: 15024091-Fig-3b

not Pias1--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 10 30 60+ min
    *** unaffected by: Pias1 [KO]
    *** source: 17606919-Fig-7b
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mBMMs in BMS "cytoplasmic-extracts"
    *** times: 0++ 10 30+ min
    *** unaffected by: Pias1 [KO]
    *** source: 15657437-Fig-6a

not Pias4--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 10 30 60+ min
    *** unaffected by: Pias4 [KO]
    *** source: 17606919-Fig-7a

not Pkr--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0++ 15+ 30+ 60++ 120++ 240++ min
    *** unaffected by: Pkr [KO]
    *** source: 10648614-Fig-3

Ppp2cb--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: HEK293 in BMS
    *** times: 0+ 5+ 15 30 60+ 120+ min
    *** comment: prolonged by xPpp2cb [addition]
    *** source: 14585847-Fig-5a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: HELA in BMS
    *** times: 0+ 5+ 15 30 60+ 120+ min
    *** comment: repressed at later times by Ppp2cb [RNAi]
    *** source: 14585847-Fig-4c

not Raf1--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMLS
    *** times: 0++ 5+ 10 20 min
    *** does not req: Raf1 [KO]
    *** source: 11296228-Fig-7b

not Rela--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (15 min)
    *** cells: mEFs<Rela~null> in BMS
    *** partially reversed by: LMB [pretreatment]
    *** source: 11416149-Fig-1c

Ripk1--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: JURKAT<Pten~null> in BMS
    *** times: 0+ 15 30 min
    *** reqs: Ripk1 [KO]
    *** source: 15572679-Fig-2d
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: JURKAT<Pten~null> in BMS
    *** times: 0+ 15 30 min
    *** reqs: Ripk1 [KO]
    *** source: 15572679-Fig-3b
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: JURKAT<Pten~null> in BMS
    *** times: 0+ 15 30 min
    *** reqs: Ripk1 [KO]
    *** source: 15572679-Fig-5d
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0++ 5+ 15 30+ 60++ min
    *** reqs: Ripk1 [KO]
    *** source: 10795740-Fig-1a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 10 30 min
    *** partially reqs: Ripk1 and/or Myd88 [DKO]
    *** source: 16115877-Fig-4a,4b,4c

Stat1--  inhibition by overexpression

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (30 min)
    *** cells: U3A<Stat1~null> in BMS
    *** reversed by: xStat1 [addition]
    *** source: 10848577-Fig-5a

Syk--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: JURKAT-H33HJ-JA1 in BMLS
    *** times: 0+ 10 15 20 min
    *** reqs: Syk [null-mut]
    *** source: 16291755-Fig-7b
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (tnr)
    *** cells: MCF7 in BMLS
    *** reqs: Syk [RNAi]
    *** source: 16291755-Fig-7e
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: JURKAT<Pten~null> in BMS
    *** times: 0+ 5 10 15 30 60+ min
    *** reversed by: Piceatannol [addition]
    *** source: 15240695-Fig-4a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: JCam1 in BMS "Syk and Lck deficient"
    *** times: 0+ 5+ 10 15 30 60+ min
    *** unaffected by: xLck [addition]
    *** source: 15240695-Fig-4b

not Tab1

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (30 min)
    *** cells: MCF10A in BMS "cytoplasmic fraction"
    *** does not req: Tab1 [RNAi]
    *** source: 18037881-Fig-S5
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 15 30+ 60+ min
    *** does not req: Tab1 [KO]
    *** source: 16260493(D)

Tab2-- or Tab3--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 15 30+ 60+ min
    *** does not req: Tab2 [KO]
    *** source: 16260493(D)
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (30 min)
    *** cells: MCF10A in BMS "cytoplasmic fraction"
    *** partially reqs: Tab2 [RNAi]
    *** source: 18037881-Fig-5b
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: HELA in BMS
    *** times: 0+ 2 6 min
    *** does not req: Tab2 [RNAi]
    *** does not req: Tab3 [RNAi]
    *** partially reqs: Tab2 and/or Tab3 [DRNAi]
    *** source: 14633987-Fig-7b
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 15 30+ min
    *** does not req: Tab2 [KO]
    *** source: 12556483-Fig-4a

Tak1--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: HELA in BMS
    *** times: 0+ 2+ 5+ 10 20 60 min
    *** partially reqs: Tak1 [RNAi]
    *** source: 12547194(D)
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: HEK293 in BMS
    *** times: 0+ 5+ 10+ 20 30 min
    *** reqs: Tak1 [RNAi]
    *** source: 15327770(D)
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 15 30 min
    *** reqs: Tak1 [KO]
    *** source: 16186825(D)
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 15 30+ 60+ min
    *** reqs: Tak1 [KO]
    *** source: 16260493(D)
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (30 min)
    *** cells: MCF10A in BMS "cytoplasmic fraction"
    *** reqs: Tak1 [RNAi]
    *** source: 18037881-Fig-5a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs<Tak1~null><xTak1> in BMS
    *** times: 0++ 5+ 10+ 15 30+ min
    *** reqs: xTak1 [omission]
    *** reversed by: xTak1(K158R) [addition]
    *** source: 20038579-Fig-7a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs<Tak1~null><xTak1> in BMS
    *** times: 0++ 5+ 10+ 15 min
    *** reversed by: xTak1(K158R) [addition]
    *** source: 20038579-Fig-S3a

not Tax1bp1--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (15 min)
    *** cells: mEFs<Tax1bp1~null><xTax1bp1> in BMS
    *** unaffected by: xTax1bp1(S593A) [substitution]
    *** unaffected by: xTax1bp1(S593A/S666A) [substitution]
    *** unaffected by: xTax1bp1(S666A) [substitution]
    *** source: 21765415-Fig-2f

not Tbk1--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 1+ 3 9 27 90+ min
    *** does not req: Tbk1 [KO]
    *** source: 10990461-Fig-5a

Tnfaip3--  ???

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (20 min)
    *** cells: HEK293T in BMS
    *** reversed by: xTnfaip3 [addition]
    *** source: 10755617(D)
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 10 20 30 60++ 90++ 120++ 180+ min
    *** comment: return of signal after 60 min reqs Tnfaip3 [KO]
    *** source: 11009421-Fig-3b
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mThyCs in BMS
    *** times: 0+ 10 20 30 60+ min
    *** comment: return of signal at 60 min reqs Tnfaip3 [KO]
    *** source: 11009421-Fig-2c

TnfR1--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 5+ 15 30+ min
    *** reqs: TnfR1 [KO]
    *** source: 12654725-Fig-4c
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mBMMs in BMS
    *** times: 0+ 5 15 30 45+ min
    *** reqs: TnfR1 [KO]
    *** source: 18641654-Fig-1b
  *** Ikba[phosAb] phos(S32/S36)[phosAb] is increased irt Tnf (times)
    *** cells: mBMMs in BMS
    *** times: 0+ 5 15+ 30+ 45+ min
    *** reqs: TnfR1 [KO]
    *** source: 18641654-Fig-1b

Tpl2--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 10 20 30 45+ min
    *** reqs: Tpl2 [KO]
    *** source: 15833743-Fig-5a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: JURKATT<xNfkb1> in BMS
    *** times: 0++ 2+ 8 15 30 min
    *** unaffected by: xTpl2(D270A)"KD" [addition]
    *** source: 9950430-Fig-7b

Tradd--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mBMMs in BMS
    *** times: 0+ 5 15 30 45+ min
    *** partially reqs: Tradd [KO]
    *** source: 18641654-Fig-1b
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 5+ 15 30 45+ min
    *** reqs: Tradd [KO]
    *** source: 18641654-Fig-1a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 5 30 45+ min
    *** reqs: Tradd [KO]
    *** source: 18641654-Fig-1a

Traf2--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 10 30 min
    *** partially reqs: Traf2 and/or Traf5 [DKO]
    *** source: 11479302-Fig-1c
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (10 min)
    *** cells: mEFs in BMS
    *** reqs: Traf2 and/or Traf5 [DKO]
    *** source: 12842894-Fig-4
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0++ 5+ 15 30+ 60++ min
    *** partially reqs: Traf2 [KO]
    *** source: 10795740-Fig-1a

Ube1--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: U2OS in BMS
    *** times: 0+ 5+ 10 min
    *** reqs: Ube1 [RNAi]
    *** source: 19854138-Fig-S3d

Ube2ds--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: U2OS in BMS
    *** times: 0+ 5+ 15 min
    *** partially reqs: Ube2ds [RNAi]
    *** source: 19854138-Fig-4a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: U2OS<Ube2ds~null><xUbe2d3> in BMS
    *** times: 0+ 5+ 15 min
    *** unaffected by: xUbe2d3(C85A) [substitution]
    *** source: 19854138-Fig-4b


not Ubc13--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (10 min)
    *** cells: HELA in BMS
    *** does not req: Ubc13 [RNAi]
    *** source: 14713952-Fig-4e
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (15 min)
    *** cells: HELA<xTraf2><xUbc13> in BMS
    *** unaffected by: xUbc13(C87A) [substitution]
    *** source: 14713952-Fig-3d
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: U2OS in BMS
    *** times: 0+ 5+ 15 min
    *** does not req: Ubc13 [RNAi]
    *** source: 19854138-Fig-3a,3c
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: U2OS<Ubc13~null><xUbc13(C87A)> in BMS
    *** times: 0+ 5+ 15 min
    *** source: 19854138-Fig-3c

Ubiq--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: U2OS in BMS
    *** times: 0+ 5+ 15 min
    *** reqs: Ubiq [RNAi]
    *** source: 19854138-Fig-2a,2c

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: U2OS<Ubiq~null><xUbiq> in BMS
    *** times: 0+ 5+ 15 min
    *** unaffected by: xUbiq(K63R) [substitution]
    *** source: 19854138-Fig-2c
  *** Ikba[Ab] prot-exp[WB] is unchanged irt Tnf (10 min)
    *** cells: U2OS<Ubiq~null><xUbiq(K63R)> in BMS
    *** source: 19854138-Fig-S5a

not Usp21--

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: HELA in BMS
    *** times: 0++ 5++ 10 30+ min
    *** does not req: Usp21 [RNAi]
    *** source: 19910467-Fig-4b

======================
Required Ikba features
======================

  *** xIkba[Ab] prot-exp[WB] is decreased irt Tnf (25 min)
    *** cells: HELA in BMS
    *** reversed by: xIkba(S36A) [substitution]
    *** reversed by: xIkba(S32A) [substitution]
    *** reversed by: xIkba(S32A/S36A) [substitution]
    *** reversed by: xIkba(D31A) [substitution]
    *** reversed by: xIkba(D31A/D35A) [substitution]
    *** partially reversed by: xIkba(S32T) [substitution]
    *** unaffected by: xIkba(S234A) [substitution]
    *** source: 8657102-Fig-2b
  *** xIkbb[Ab] prot-exp[WB] is decreased irt Tnf (30 min)
    *** cells: HELA in BMS
    *** reversed by: xIkbb(S19A) [substitution]
    *** reversed by: xIkbb(S23A) [substitution]
    *** reversed by: xIkbb(S19A/S23A) [substitution]
    *** source: 8657102-Fig-5
  *** xIkba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: HELA in BMS
    *** times: 0++ 5+ 10 20 min
    *** reversed by: xIkba(S32A) [substitution]
    *** reversed by: xIkba(S36A) [substitution]
    *** reversed by: xIkba(S32A/S36A) [substitution]
    *** reversed by: xIkba(D31A) [substitution]
    *** reversed by: xIkba(D31A/D35A) [substitution]
    *** partially reversed by: xIkba(S32T) [substitution]
    *** unaffected by: xIkba(S36T) [substitution]
    *** unaffected by: xIkba(S234A) [substitution]
    *** source: 8657102-Fig-2a
  *** xIkba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: EL4<xIkba> in BMS
    *** times: 0++ 5 15 60+ min
    *** reversed by: xIkba(S32G) [substitution]
    *** source: 7878466-Fig-1d
  *** xIkba[Ab] prot-exp[WB] is decreased irt Tnf (15 min)
    *** cells: 70Z3<xCd14><xIkba> in BMS "pretreated with ZVAD"
    *** reversed by: xIkba(S32A/S36A) [substitution]
    *** source: 12138192-Fig-1c

=========
chemicals
=========

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (15 min)
    *** cells: mEFs in BMS
    *** partially reversed by: LMB [pretreatment]
    *** partially reversed by: MG132 [pretreatment]
    *** source: 11416149-Fig-1b
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (30 min)
    *** cells: EAHY926 in BMLS
    *** reversed by: Methyl-beta-cyclodextrin [addition]
    *** source: 15793306-Fig-3a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: EAHY926 in BMLS
    *** times: 0+ 10+ 20 30 min
    *** unaffected by: Methyl-beta-cyclodextrin [addition]
    *** source: 15793306-Fig-3a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: SAOS2 in BMS
    *** times: 0+ 8 15 min
    *** reversed by: MG132 [addition]
    *** source: 15073170-Fig-2e
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (3 min)
    *** cells: HELA in BMS
    *** reversed by: Bay117082 [addition]
    *** source: 12842894-Fig-6
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (5 min)
    *** cells: HELA in BMS
    *** reversed by: ALLN [addition]
    *** source: 12842894-Fig-3a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: U2OS in BMS
    *** times: 0 5+ 10+ min
    *** unaffected by: SmacMimetic [addition]
    *** source: 19854138-Fig-7a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: HT1080 in BMS
    *** times: 0++ 5+ 30 min
    *** reversed by: BV6 [addition]
    *** source: 18621737-Fig-1c
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: HT1080 in BMS
    *** times: 0++ 5+ 30 min
    *** reversed by: BV6 [addition]
    *** source: 18621737-Fig-2a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (20 min)
    *** cells: mBMMs in BMS "cytoplasmic extracts"
    *** reversed by: PS1145 [pretreatment]
    *** source: 15199157-Fig-1a
  *** Mek1[phosAb] phos(sitenr)[phosAb] is increased irt Tnf (15 min)
    *** cells: mBMMs in BMS
    *** reversed by: PS1145 [pretreatment]
    *** source: 15199157-Fig-3c
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (15 min)
    *** cells: HELA in BMS
    *** reversed by: ALLN [pretreatment]
    *** reversed by: LMB [pretreatment]
    *** source: 10655476-Fig-1b
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (15 min)
    *** cells: HELA in BMS "cytoplasmic-extracts"
    *** reversed by: LMB [pretreatment]
    *** unaffected by: SN50 [pretreatment]
    *** source: 10655476-Fig-6b
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (15 min)
    *** cells: HELA in BMS "enucleated before treatment"
    *** reversed by: ALLN [pretreatment]
    *** unaffected by: LMB [pretreatment]
    *** source: 10655476-Fig-2b

=========
no extras
=========

  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: MRC5 in BMLS
    *** times: 0+ 5 20 min
    *** source: 9261174-Fig-4
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: MCF7 in BMS
    *** times: 0+ 15 30 60+ min
    *** source: 16280327-Fig-2
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: THP1 in BMS
    *** times: 0+ 3+ 5 10 30 min
    *** source: 10477696-Fig-6a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: THP1 in BMS
    *** times: 0+ 5 10 20 30 40 50+ 60+ 75+ 90+ min
    *** source: 10455128-Fig-5b
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (15 min)
    *** cells: SAOS2 in BMS
    *** source: 15073170-Fig-2c
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: HEK293 in BMS
    *** times: 0+ 2 5 10 min
    *** source: 10356400-Fig-1
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: HEK293T in BMS
    *** times: 0+ 5 10 20 30+ 60+ min
    *** source: 16135789-Fig-2a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: HEK293<xCd40> in BMS
    *** times: 0+ 30 300+ min
    *** source: 12374738-Fig-1d
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: HEK293 in BMS
    *** times: 0+ 2+ 5 10 20 min
    *** source: 12842894-Fig-2b
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: HELA in BMS
    *** times: 0+ 2+ 5 10 20 min
    *** source: 12842894-Fig-2a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: 3T3L1 in BMS "differentiated into adipocytes"
    *** times: 0+ 5+ 10 15 30 60+ min
    *** source: 17500068-Fig-4a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: 3T3L1 in BMS "differentiated into adipocytes"
    *** times: 0+ 5 15 30 60 120+ 360+ 720+ min
    *** source: 17500068-Fig-8a
  *** Ikba[Ab] prot-exp[WB] is decreased irt anti-TnfR1 (times)
    *** cells: 3T3L1 in BMS "differentiated into adipocytes"
    *** times: 0+ 5 15 30 60 120+ 360+ 720+ min
    *** source: 17500068-Fig-8a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: U2OS in BMS
    *** times: 0 5 20 min
    *** source: 12917690-Fig-2c
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (10 min)
    *** cells: U2OS in BMS
    *** source: 19854138-Fig-S5a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: HEK293T in BMS
    *** times: 0++ 2++ 5+ min
    *** source: 12867425-Fig-4j
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: HELA in BMS
    *** times: 0++ 2++ 5+ 10 20 30 min
    *** source: 12867425-Fig-1a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: EL4 in BMS
    *** times: 0+ 5 15 60++ min
    *** source: 7878466-Fig-1a
  *** xIkba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: EL4<xIkba> in BMS
    *** times: 0++ 5 15 60+ min
    *** source: 7878466-Fig-1a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (15 min)
    *** cells: hUVECs in BMS
    *** source: 11714736-Fig-4d
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mBMDCs in BMS
    *** times: 0+ 30 60+ min
    *** source: 20185725-Fig-S1e
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mBMMs in BMS
    *** times: 0+ 30 60+ min
    *** source: 20185725-Fig-S1d
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (30 min)
    *** cells: MCF7 in BMLS
    *** source: 17693255-Fig-S1a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (30 min)
    *** cells: MCF7 in BMLS
    *** source: 17693255-Fig-S1b
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: MCF7 in BMLS
    *** times: 0+++ 5++ 10+ 20+ 30++ min
    *** source: 17693255-Fig-1a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: MDAMB453 in BMLS
    *** times: 0+++ 5+++ 10++ 20+ 30+ min
    *** source: 17693255-Fig-1a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: MDAMB453 in BMLS
    *** times: 0+++ 10++ 20+ 30+ min
    *** source: 18949383-Fig-1a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: HEK293<xIkba> in BMS
    *** times: 0++ 5++ 10+ 20+ 30+ 60++ min
    *** source: 10655476-Fig-3a
  *** xIkba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: HEK293<xIkba> in BMS
    *** times: 0++ 5++ 10++ 20+ 30+ 60+ min
    *** source: 10655476-Fig-3a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0++ 10 25 40+ 55++ 70++ min
    *** comment: Tnf was removed after the first 10 min
    *** source: 11416149-Fig-3a
  *** Ikba[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: T98G in BMS
    *** times: 0++ 12+ 30 60+ 90++ 120++ 240++ min
    *** source: 10648614-Fig-2a



at later times

  *** Ikba[Ab] prot-exp[WB] is unchanged irt Tnf (times)
    *** cells: mBMMs in BMS
    *** times: 0 2+ 4+ 6+ hr
    *** source: 20185725-Fig-3d


