===========
DNA-binding
===========

reqs Stat4--

  *** Jun[Ab] boundto(IL2Ra-gene)[ChIP] is increased irt IL12 (times)
    *** cells: mSpCs in BMS "pretreated with anti-Cd3 for 72 hr"
    *** times: 0 4+ 8+ hr
    *** reqs: Stat4 [KO]
    *** source: 14660657-Fig-5a

Effect of Cotreatments

  *** Jun[Ab] boundto(Ifng-gene)[ChIP] is increased irt IL12 (1 hr)
    *** cells: hPBTCs in BMS "preactivated with Cd3/Cd28"
    *** unaffected by: anti-Cd28 [cotreatment]
    *** source: 15522880-Fig-3a
  *** Jun[Ab] snaggedby[WB] oligo[agarose] is increased irt IL12 (tnr)
    *** cells: 2D6 in BMS "IL12-deprived" "nuclear-extracts"
    *** enhanced by: IL18 [cotreatment]
    *** source: 11801649-Fig-7a
  *** Jun[Ab] snaggedby[WB] oligo[agarose] is increased irt IL12 (tnr)
    *** cells: 2D6 in BMS "IL12-deprived" "nuclear-extracts"
    *** enhanced by: IL18 [cotreatment]
    *** source: 11801649-Fig-7b

Chemicals

  *** Jun[Ab] boundto(Ifng-gene)[ChIP] is increased irt IL12 (1 hr)
    *** cells: hPBTCs in BMS "preactivated with Cd3/Cd28"
    *** unaffected by: CsA [pretreatment]
    *** inhibited by: Rapamycin [pretreatment]
    *** source: 15522880-Fig-3a

=====================
Relocation to Nucleus
=====================

  *** Jun[Ab]IP infraction(nuclear)[WB] is increased irt IL12 (tnr)
    *** cells: 2D6 in BMS "IL12-deprived"
    *** enhanced by: IL18 [cotreatment]
    *** comment: nuclear Jun is not phosed on S63
    *** source: 11801649-Fig-6b
