======================
Direct Phosphorylation
======================

  *** rMkk4(mnr)"KD"[32P] phos[32P-ATP] is increased by rMekk4(CatDom)"CA"
    *** cells: none
    *** source: 9305639-Fig-9a
  *** rMkk4[32P] phos[32P-ATP] is increased by rMekk4(CatDom)"CA"
    *** cells: none
    *** inhibited by: rMekk4(CatDom/K116M)"KD" [substitution]
    *** source: 9079650-Fig-4b

=======================
Indirect Phophorylation
=======================

  *** xMkk4[tAb]IP phos(sitenr)[phosAb] is increased itpo xMekk4
    *** cells: COS7 in BMS
    *** source: 9305639-Fig-8

=====================================================
Activation of kinase activity against P38 but not Jnk 
=====================================================

  *** xMkk4[tAb]IP IVKA(Jnk1,Jun)[32P-ATP] is unchanged itpo xMekk4
    *** cells: COS7 in BMS
    *** source: 9891090-Fig-7
  *** xMkk4[tAb]IP IVKA(P38?)[32P-ATP] is increased itpo xMekk4
    *** cells: COS7 in BMS
    *** source: 9305639-Fig-8

