=====================
Phoshorylation on T68
=====================

not Atm--

  *** Chek2[Ab]IP phos(T68)[phosAb] is increased irt Hydroxyurea (24 hr)
    *** cells: hLymphoblasts in BMS
    *** does not req: Atm [fmut]
    *** source: 10973490-Fig-4c

chemicals

  *** Chek2[phosAb] phos(T68)[phosAb] is increased irt Hydroxyurea (2 hr)
    *** cells: RAJI in BMS
    *** inhibited by: Wortmannin [pretreatment]
    *** source: 16461339-Fig-1a

  *** Chek2[Ab]IP phos(T68)[phosAb] is increased irt Hydroxyurea (24 hr)
    *** cells: HEK293T in BMS
    *** source: 10973490-Fig-4a

===============
Kinase Activity
===============

  *** Chek2[Ab]IP IVKA(Cdc25c)[32P-ATP] is increased irt Hydroxyurea (20 hr)
    *** cells: AG04405<Atm~fmut> in BMS
    *** source: 10435585-Fig-6b
  *** Chek2[Ab]IP IVKA(Cdc25c)[32P-ATP] is increased irt Hydroxyurea (20 hr)
    *** cells: MRC5 in BMS
    *** source: 10435585-Fig-6b
  *** Chek2[Ab]IP IVKA(Cdc25c)[32P-ATP] is increased irt Hydroxyurea (2 hr)
    *** cells: HEK293T in BMS
    *** source: 9836640-Fig-3e
