=============
Transcription
=============

Egfr--

  *** Nos2a-gene mRNA[RTPCR] is increased irt Egf (times)
    *** cells: CHO<xEgfR> in BMLS
    *** times: 0 1+ 2+ hr
    *** inhibited by: xEgfR(R645A/R646A/R647A) [substitution]
    *** source: 15950906-Fig-5e
  *** Nos2a-gene promo-reporter[Luc] is increased irt Egf (4 hr)
    *** cells: CHO<xEgfR> in BMLS
    *** inhibited by: xEgfR(R645A/R646A/R647A) [substitution]
    *** source: 15950906-Fig-5e

Stat3--

  *** Nos2a-gene promo-reporter[Luc] is increased irt Egf (4 hr)
    *** cells: HELA in BMLS
    *** inhibited by: xStat3(mnr)"DN" [addition]
    *** source: 15950906-Fig-5g

chemicals

  *** Nos2a-gene promo-reporter[Luc] is increased irt Egf (4 hr)
    *** cells: A431 in BMLS
    *** inhibited by: AG490 [pretreatment] no-bkg-control
    *** inhibited by: AG1478 [pretreatment] no-bkg-control
    *** inhibited by: PD158780 [pretreatment] no-bkg-control
    *** source: 15950906-Fig-5a

no extras

  *** Nos2a-gene mRNA[RTPCR] is increased irt Egf (times)
    *** cells: MDAMB468 in BMLS
    *** times: 0 1+ 2++ 6++ hr
    *** source: 15950906-Fig-3a
  *** Nos2a-gene mRNA[RTPCR] is detectable-but unchanged irt Egf (times)
    *** cells: CHO in BMLS
    *** times: 0+ 1+ 2+ hr
    *** source: 15950906-Fig-5e
  *** Nos2a-gene promo-reporter[Luc] is increased irt Egf (4 hr)
    *** cells: A431 in BMLS
    *** source: 15950906-Fig-4c
  *** Nos2a[Ab] prot-exp[WB] is increased irt Egf (6 hr)
    *** cells: MDAMB468 in BMLS
    *** source: 15950906-Fig-3b


===========
Translation
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State in cells with "hyperactive Stat3,EgfR,Src"

  *** Nos2a[Ab] prot-exp[WB] is detectable
    *** cells: PANC1 in BMS
    *** does not req: Src [RNAi]
    *** source: 21573184-Fig-6b
  *** Nos2a[Ab] prot-exp[WB] is detectable
    *** cells: PANC1 in BMS
    *** partially reqs: EgfR [RNAi]
    *** source: 21573184-Fig-6b
