==============================================================
Rationale for similar response of Crk and CrkL from Egf Rules
==============================================================

===================
Recruitment to Trka
===================

  *** Crks[Ab] copptby[WB] xTrka[Ab] is increased irt Ngf (times)
    *** cells: PC12<xTrka> in BMS
    *** times: 0 1+ 2++ 5+++ 60++ 180++ min
    *** source: 15167895-Fig-5c
  *** xTrka[Ab] copptby[WB] Crks[Ab] is increased irt Ngf (10 min)
    *** cells: PC12NNR5<xTrka> in BMS
    *** unaffected by: xTrka(Y490F) [substitution]
    *** source: 15167895-Fig-5a

===========================
Phosphorylation on Tyrosine  Crk only ???
===========================

  *** Crk[Ab]IP Yphos[pYAb] is increased irt Ngf (times)
    *** cells: PC12 in BMLS
    *** times: 0 2++ 5++ 15 30 60 min
    *** source: 11278445-Fig-5a

  *** CrkL[Ab]IP Yphos[pYAb] is unchanged irt Ngf (times)
    *** cells: PC12 in BMLS
    *** times: 0 5 10 30 60 min
    *** source: 11466412-Fig-4a

================================================
Coprecipitation with other Trka binding proteins
================================================

Arms--

  *** CrkL[Ab] copptby[WB] Arms[Ab] is increased irt Ngf (times)
    *** cells: PC12<xTrka> in BMS
    *** times: 0 1+ 5+ 15+ 20+ min
    *** source: 15167895-Fig-5b

Frs2--

  *** Crk[Ab] copptby[WB] Frs2[Ab] is increased irt Ngf (times)
    *** cells: PC12 in BMLS
    *** times: 0 2+ 5+ 15+ 30+ 60+ min
    *** source: 11278445-Fig-8b


