===========================
Phosphorylation on Tyrosine
===========================

IfngR2--

  *** Jak2[Ab]IP Yphos[pYAb] is increased irt Ifng (10 min)
    *** cells: CHOK1<xHlab7><xIfngR1><xIfngR2> in BMS
    *** reqs: xIfngR2 [omission]
    *** inhibited by: xIfngR2(1-285) [substitution]
    *** source: 7673114-Fig-4
  *** Jak2[Ab]IP Yphos[pYAb] is increased irt Ifng (10 min)
    *** cells: CHOK1<xHlab7><xIfngR1><xIfngR2> in BMS
    *** reqs: xIfngR2 [omission]
    *** inhibited by: xIfngR2(1-285) [substitution]
    *** source: 7673114-Fig-6

Jak2 kinase activity

  *** Jak2[Ab]IP Yphos[pYAb] is increased irt Ifng (15 min)
    *** cells: 2C4 in BMS
    *** inhibited by: xJak2(mnr)"KD" [addition]
    *** source: 7537214-Fig-7c


no extras

  *** Jak2[Ab]IP Yphos[pYAb] is increased irt Ifng (5 min)
    *** cells: H4IIE in BMS
    *** source: 12087100-Fig-2b
  *** Jak2[Ab]IP Yphos[pYAb] is increased irt Ifng (10 min)
    *** cells: 3112<xIfngR1> in BMS
    *** source: 7615558-Fig-3b
  *** Jak2[Ab]IP Yphos[pYAb] is increased irt Ifng (15 min)
    *** cells: 2C4 in BMS
    *** source: 7537214-Fig-7b
  *** Jak2[Ab]IP Yphos[pYAb] is increased irt Ifng (15 min)
    *** cells: 2FTGH in BMS
    *** source: 7537214-Fig-1c
  *** Jak2[Ab]IP Yphos[pYAb] is increased irt Ifng (15 min)
    *** cells: HELA in BMS
    *** source: 7514165-Fig-4c
  *** Jak2[Ab]IP Yphos[pYAb] is increased irt Ifng (times)
    *** cells: HELA in BMS
    *** times: 0 1+ 2+ 5+ min
    *** source: 7514165-Fig-2b
  *** Jak2[Ab]IP Yphos[pYAb] is unchanged irt Ifng (10 min)
    *** cells: L929<xIfngR1> in BMS
    *** comment: L929 cells are mouse and do not respond to hIfng
    *** source: 7615558-Fig-3b

===============
Kinase Activity
===============

IfngR2--

  *** Jak2[Ab]IP IVKA(peptide)[32P-ATP] is increased irt Ifng (10 min)
    *** cells: CHOK1<xHlab7><xIfngR1><xIfngR2> in BMS
    *** reqs: xIfngR2 [omission]
    *** inhibited by: xIfngR2(1-285) [substitution]
    *** source: 7673114-Fig-3

no extras

  *** Jak2[Ab]IP IVKA(auto)[32P-ATP] is increased irt Ifng (15 min)
    *** cells: 2FTGH in BMS
    *** source: 7537214-Fig-3
  *** Jak2[Ab]IP IVKA(auto)[32P-ATP] is increased irt Ifng (tnr)
    *** cells: HELA in BMS
    *** source: 7615558-Fig-5
  *** Jak2[Ab]IP IVKA(auto)[32P-ATP] is unchanged irt Ifng (15 min)
    *** cells: U4A<Jak1~null> in BMS
    *** source: 7537214-Fig-3
  *** Jak2[Ab]IP IVKA(auto)[pYAb] is increased irt Ifng (tnr)
    *** cells: HELA in BMS
    *** source: 7615558-Fig-6
