=====================================================
Proteins required for Erk Phosphorylation on TEY site
=====================================================

inhibited by Abi1--

  *** xErk2[tAb]IP phos(TEY)[phosAb] is increased irt Egf (5 min)
    *** cells: COS7 in BMLS
    *** partially inhibited by: xAbi1 [addition]
    *** source: 11777939-Fig-4b

ArhGef7--  ???

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (times)
    *** cells: NIH3T3 in BMLS
    *** times: 0 10++ 24+ 45 min
    *** bkg reqs: ArhGef7 [RNAi]
    *** source: 16892055-Fig-1b

Braf--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: CCD18CO in BMLS
    *** partially reqs: Braf [RNAi] no-bkg-control
    *** source: 15258589-Fig-3a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (times)
    *** cells: mEFs in BMLS
    *** times: 0 5+++ 10++ 30+ min
    *** partially reqs: Braf [KO]
    *** source: 15199148-Fig-2a

not Brap--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (times)
    *** cells: HELA in BMS
    *** times: 0 10+++ 20++ 30+ min
    *** does not req: Brap [RNAi]
    *** source: 14724641-Fig-2f

Cdc42--  ???

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (times)
    *** cells: NIH3T3 in BMLS
    *** times: 0 10+ 45 min
    *** bkg reqs: Cdc42 [RNAi]
    *** source: 16892055-Fig-1a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (times)
    *** cells: NIH3T3 in BMLS
    *** times: 0 10++ 24+ 45 min
    *** bkg inhibited by: xCdc42(T17N) [addition]
    *** source: 16892055-Fig-1a

inhibited by Dok2--

  *** xErk2[tAb]IP phos(TEY)[phosAb] is increased irt Egf (times)
    *** cells: COS1 in BMLS
    *** times: 0 2+ 5++ 10+++ min
    *** inhibited by: xDok2 [addition]
    *** source: 15831486-Fig-1,2
  *** xErk2[tAb]IP phos(TEY)[phosAb] is increased irt Egf (times)
    *** cells: COS1 in BMS
    *** times: 0 2+ 5++ 10++ min
    *** partially inhibited by: xDok2 [addition]
    *** source: 10508618-Fig-3a

reqs Fak2--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (15 min)
    *** cells: A431 in BMS
    *** partially inhibited by: xFak2(K457A/D576A)"DN" [addition]
    *** source: 14963038-Fig-6b

Gabs--

Requirement for Gab1 phos(Y627/Y659) or Gab2 phos(Y614/Y643)
for Erk Phosphorylation on TEY site
~/evidence/Egf-Evidence/196.Gabs.txt

Git1--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (times)
    *** cells: HEK293 in BMLS
    *** times: 0 2+ 5+ 10 20 min
    *** comment: prolonged by xGit1 [addition]
    *** source: 14701758-Fig-6a,6b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (times)
    *** cells: HELA in BMLS
    *** times: 0 5+ 10+ min
    *** partially reqs: Git1 [RNAi]
    *** source: 14701758-Fig-7b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (times)
    *** cells: HEK293<xGit1> in BMS
    *** times: 0 2+ 5+ 10++ min
    *** inhibited by: xGit1(del(420-475)) [substitution]
    *** comment: inhibition at 10 min only
    *** source: 15923189-Fig-5c

Grb2--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (15 min)
    *** cells: COS1 in BMS
    *** unaffected by: xGrb2 [addition]
    *** source: 14498832-Fig-4

Hras--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: 3Y1<xEgfR> in BMLS
    *** inhibited by: xHras(S17N)"DN" [addition]
    *** source: 10611224-Fig-3a
  *** xErk2[tAb]IP phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: COS1 in BMLS
    *** inhibited by: xHras(S17N)"DN" [addition]
    *** source: 12167697-Fig-2a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (20 min)
    *** cells: HELA in BMLS
    *** partially inhibited by: xHras(S17N)"DN" [addition]
    *** source: 9790194-Fig-2b

not IL17Rd1--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (times)
    *** cells: HELA in BMS
    *** times: 0 5+ 10+ min
    *** does not req: IL17Rd [RNAi]
    *** source: 15239952-Fig-6b

not Jun--

  *** xErk1[tAb]IP phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: COS7 in BMLS
    *** unaffected by: xJun [addition]
    *** unaffected by: xJun(mnr)"Tam67" [addition]
    *** unaffected by: xJun(mnr)"DBM3" [addition]
    *** source: 12738796-Fig-5a
  *** xErk1[tAb]IP phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: COS7 in BMLS
    *** unaffected by: SP600125 [addition]
    *** source: 12738796-Fig-4a

Ksr1-- ???

  *** Erks[Ab] copptby[WB] xKsr1[tAb] is increased irt Egf (5 min)
    *** cells: COS in BMLS
    *** source: 11741534-Fig-1,5b

Mek1--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (5 min)
    *** cells: HEK293 in BMS
    *** inhibited by: xMek1(265-301) [addition]
    *** source: 9677429-Fig-3b

not Mek5--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (20 min)
    *** cells: HELA in BMLS
    *** unaffected by: xMek5(mnr)"DN" [addition]
    *** source: 9790194-Fig-2b

not Mekk1--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (tnr)
    *** cells: mEFs in BMS
    *** does not req: Mekk1 [KO]
    *** source: 12048245-Fig-4b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (5 min)
    *** cells: CHO<xEgfR><xInsR> in BMS
    *** times: 0 2++ 5++ 15+ min
    *** unaffected by: xMekk1(mnr)"DN" [addition]
    *** source: 15192046-Fig-8b

not Mekk2--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (15 min)
    *** cells: HELA in BMLS
    *** does not req: Mekk2 [RNAi]
    *** source: 16581779-Fig-5b

not Mekk3--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (15 min)
    *** cells: HELA in BMLS
    *** unaffected by: xMekk3(K391W)"DN" [addition]
    *** source: 10593883-Fig-4b

Mlk3--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: WI38 in BMLS
    *** partially reqs: Mlk3 [RNAi]
    *** source: 15258589-Fig-2c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: CCD18CO in BMLS
    *** bkg reqs: Mlk3 [RNAi]
    *** source: 15258589-Fig-2a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: CCD18CO in BMLS
    *** reqs: Mlk3 [RNAi] no-bkg-control
    *** source: 15258589-Fig-2a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: CCD18CO in BMLS
    *** partially reqs: Mlk3 [RNAi]
    *** source: 15258589-Fig-2a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: CCD18CO in BMLS
    *** reqs: Mlk3 [RNAi] no-bkg-control
    *** source: 15258589-Fig-3a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: CCD18CO in BMLS
    *** reqs: Mlk3 [RNAi] no-bkg-control
    *** source: 15258589-Fig-3c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: HEK293 in BMLS
    *** reqs: Mlk3 [RNAi]
    *** source: 16537381-Fig-1b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: HEK293<Mlk3~null><xMlk3> in BMLS
    *** unaffected by: xMlk3(K144R)"KD" [substitution]
    *** source: 16537381-Fig-1b
  *** xErk1[tAb]IP phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: COS7 in BMLS
    *** partially inhibited by: xMlk3 [addition]
    *** partially inhibited by: xMlk3 + xJun [addition]
    *** unaffected by: xMlk3 + xJun(mnr)"Tam67" [addition]
    *** unaffected by: xMlk3 + xJun(mnr)"DBM3" [addition]
    *** source: 12738796-Fig-5a
 -----------------------------------------------------------------
  *** xErk1[tAb]IP phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: COS7 in BMLS
    *** inhibited by: xMlk3 [addition]
    *** source: 12738796-Fig-3b
  *** xErk1[tAb]IP phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: COS7 in BMLS
    *** partially inhibited by: xMlk3 [addition]
    *** source: 12738796-Fig-4a
  *** xErk1[tAb]IP phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: COS7 in BMLS
    *** partially inhibited by: xMlk3 [addition]
    *** source: 12738796-Fig-4b
 -------------------- contradiction -----------------------------
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (times)
    *** cells: A549 in BMLS
    *** times: 0+ 5++ 10++ 30++ 60++ 120+ min
    *** does not req: Mlk3 [RNAi]
    *** source: 18851832-Fig-2c

not Mras--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (times)
    *** cells: mAstrocytes in BMLS
    *** times: 0 2+ 5+ 15+ 40+ 90+ min
    *** does not req: Mras [KO]
    *** source: 16980617-Fig-7a

not Msk1-- or Msk2--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (5 min)
    *** cells: mEFs in BMLS
    *** does not req: Msk2 [KO]
    *** does not req: Msk1 [KO]
    *** does not req: Msk1 or Msk2 [DKO]
    *** source: 11909979-Fig-4a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (times)
    *** cells: mESCs in BMLS
    *** times: 0 10+ 20+ 30+ min
    *** does not req: Msk1 [KO]
    *** source: 11018520-Fig-3c

Muc20-- ???

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (5 min)
    *** cells: HEK293 in BMLS
    *** unaffected by: xMuc20 [addition]
    *** source: 15314156-Fig-2a

not Pak1--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (5 min)
    *** cells: HELA in BMS
    *** does not req: Pak1 [RNAi]
    *** does not req: Pak1 or Pak2 [DRNAi]
    *** source: 16129686-Fig-3a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (5 min)
    *** cells: NIH3T3 in BMLS
    *** unaffected by: xPak1(83-149)"DN" [addition]
    *** source: 16129686-Fig-3a

not Pak2--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (5 min)
    *** cells: HELA in BMS
    *** does not req: Pak2 [RNAi]
    *** does not req: Pak1 or Pak2 [DRNAi]
    *** source: 16129686-Fig-3a

Pld1-- and/or Pld2--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (30 min)
    *** cells: 3Y1<xEgfR> in BMS
    *** enhanced by: xPld1 [addition]
    *** partially inhibited by: xPld1(K898R)"CIA" [addition]
    *** enhanced by: xPld2 [addition]
    *** partially inhibited by: xPld2(K758R)"CIA" [addition]
    *** source: 11134345-Fig-8d

not Ppp2r1a--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (times)
    *** cells: PC63 in  BMHIS
    *** times: 0 5++ 15+ 30 min
    *** does not req: Ppp2r1a [RNAi]
    *** source: 16129692-Fig-2a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (times)
    *** cells: PC63 in  BMHIS
    *** times: 0 5+++ 20++ 45++ 90++ 240+ min
    *** comment: sustained signal (20-240 min) reqs Ppp2r1a [RNAi]
    *** source: 16129692-Fig-3a

not Ptk6--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (5 min)
    *** cells: SYF<Src~null><Yes1~null><Fyn~null> in BMLS
    *** unaffected by: xPtk6 [addition]
    *** source: 20606012-Fig-6b

inhibited by Ptpn6--

  *** Erks[phosAb] phos(TEY)[phosAb] is decreased itpo xPtpn6
    *** cells: HEK293<xEgfR> in BMS "treated with Egf for 5 min"
    *** source: 9733788-Fig-5b

not Raf1--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: mEFs in BMLS
    *** does not req: Raf1 [KO]
    *** unaffected by: kRaf1(Y340F/Y341F) [substitution]
    *** source: 11296227-Fig-5b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (times)
    *** cells: mEFs in BMLS
    *** times: 0 2++ 5+++ 10+ 20+ 60 min
    *** does not req: Raf1 [KO]
    *** unaffected by: kRaf1(Y340F/Y341F) [substitution]
    *** source: 11296227-Fig-5a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: mEFs in BMLS
    *** does not req: Raf1 [KO]
    *** source: 11296228-Fig-6d
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (times)
    *** cells: mEFs in BMLS
    *** times: 0 2+++ 5+++ 15++ 45+ min
    *** does not req: Raf1 [KO]
    *** source: 11296228-Fig-6e
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (5 min)
    *** cells: rEFs in BMLS
    *** does not req: Raf1 [RNAi]
    *** source: 17314031-Fig-3
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (tnr)
    *** cells: mEFs in BMS
    *** does not req: Raf1 [KO]
    *** source: 12048245-Fig-4a
  --------- contradiction ----------------------------------------
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: CCD18CO in BMLS
    *** reqs: Raf1 [RNAi] no-bkg-control
    *** source: 15258589-Fig-3a

not RalGds--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (5 min)
    *** cells: COS7 in BMLS
    *** unaffected by: xRalGds [addition]
    *** unaffected by: xRalGds(del(1-297)) [addition]
    *** source: 11283245-Fig-7b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (times)
    *** cells: MCF10A in BMLS
    *** times: 0 5++ 10++ 30+ min
    *** does not req: RalGds [RNAi]
    *** source: 18285454-Fig-1c

not Rala--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: 3Y1<xEgfR> in BMLS
    *** unaffected by: xRala [addition]
    *** unaffected by: xRala(S28N)"DN" [addition]
    *** unaffected by: xRala(Q72L)"DN" [addition]
    *** unaffected by: xRala(del(1-11)) [addition]
    *** unaffected by: xRala(D49N)"DN" [addition]
    *** source: 10611224-Fig-3a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: 3Y1<xEgfR> in BMLS
    *** unaffected by: xRala(S28N)"DN" [addition]
    *** source: 10675331-Fig-3b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: HEK293 in BMLS
    *** unaffected by: xRala(S28N)"DN" [addition]
    *** source: 10675331-Fig-5c

not Raptor--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (times)
    *** cells: HC11 in BMLS "containing Ins"
    *** times: 0 7+ 15+ min
    *** unaffected by: Rapamycin [addition]
    *** source: 16984645-Fig-4a

not Rin1--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (times)
    *** cells: PC6 in BMLS
    *** times: 0 5+++ 15++ 60+ min
    *** does not req: Rin1 [RNAi]
    *** source: 16157584-Fig-3a

Rsk1--  ???

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: HEK293E in BMLS
    *** unaffected by: xRsk1 [addition]
    *** source: 12906785-Fig-1c

not Rsk2--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (30 min)
    *** cells: mESCs in BMS
    *** does not req: Rsk2 [KO]
    *** source: 10436156-Fig-6b

Shc1--  phosed on Y427

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (5 min)
    *** cells: NIH3T3<xEgfR><xShc1> in BMLS
    *** inhibited by: xShc1(Y427F) [substitution]
    *** unaffected by: xShc1(Y349F/Y350F) [substitution]
    *** source: 9121430-Fig-6c

Shoc2--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (8 min)
    *** cells: BT549 in BMS
    *** partially reqs: Shoc2 [RNAi]
    *** source: 16630891-Fig-5b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (8 min)
    *** cells: HBL100 in BMS
    *** partially reqs: Shoc2 [RNAi]
    *** source: 16630891-Fig-5b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (8 min)
    *** cells: HEK293T in BMS
    *** reqs: Shoc2 [RNAi]
    *** source: 16630891-Fig-5a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (8 min)
    *** cells: MCF10A in BMS
    *** partially reqs: Shoc2 [RNAi]
    *** source: 16630891-Fig-5b

Shp2--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (5 min)
    *** cells: mEFs in BMLS
    *** partially reqs: Shp2 [KO]
    *** source: 14967142-Fig-3b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: COS1 in BMLS
    *** partially inhibited by: xShp2(C459S) [addition]
    *** partially inhibited by: xShp2(R465E) [addition]
    *** partially inhibited by: xShp2(C459S/R465E) [addition]
    *** source: 14560030-Fig-4a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: COS1 in BMLS
    *** partially inhibited by: xShp2(C459S) [addition]
    *** source: 14560030-Fig-1a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (times)
    *** cells: COS1 in BMLS
    *** times: 0 2++ 10++ 60+ 240 min
    *** partially inhibited by: xShp2(C459S) [addition]
    *** comment: decrease after 10 min is reversed itpo xShp2 [addition]
    *** source: 14560030-Fig-1b

not Sin1--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (15 min)
    *** cells: mEFs in BMLS
    *** does not req: Sin1 [KO]
    *** source: 16962653-Fig-5b

Src--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (15 min)
    *** cells: A431 in BMS
    *** partially inhibited by: xSrc(K297R/Y530F)"DN" [addition]
    *** source: 14963038-Fig-6b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (times)
    *** cells: mEFs<Src~null><Yes1~null><Fyn~null><xSrc> in BMLS
    *** times: 0 5+ 15+ 30+ 60+ min
    *** comment: Erk-phos pattern is peculiar when xSrc is omitted
    *** source: 14967142-Fig-6c

not Stat1--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: A4318a in BMS
    *** unaffected by: xStat1 [addition]
    *** unaffected by: xStat1(Y701F) [addition]
    *** source: 17646016-Fig-2a

not Stat3--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (15 min)
    *** cells: COS1 in BMS
    *** unaffected by: xStat3 [addition]
    *** source: 14498832-Fig-4

not Tak1--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: HELA in BMS
    *** does not req: Tak1 [RNAi]
    *** source: 19687304-Fig-4a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (5 min)
    *** cells: HELA in BMS
    *** does not req: Tak1 [RNAi]
    *** source: 19393267-Fig-1b

not Ubiq--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (times)
    *** cells: U2OS in BMS
    *** times: 0 5+ 10+ min
    *** does not req: Ubiq [RNAi]
    *** source: 19854138-Fig-S3b

not Wdr83--

  *** xErk1[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: COS1<xErk1> in BMLS
    *** unaffected by: xWdr83 [addition]
    *** source: 15118098-Fig-5d
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: HELA in BMLS
    *** unaffected by: xWdr83 [addition]
    *** source: 15118098-Fig-5e
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: HELA in BMLS
    *** does not req: Wdr83 [RNAi]
    *** source: 15118098-Fig-6c

Effect of chemicals on Erk Phosphorylation on TEY site
~/evidence/Egf-Evidence/196.Chemicals.txt
No extras
~/evidence/Egf-Evidence/196.NoExtras.txt





=====================================
Cells containing Braf(V600E) mutation
=====================================

  *** Erks[phosAb] phos(TEY)[phosAb] is detectable-but unchanged irt Egf (4 hr)
    *** cells: A375 in BMLS "containing low-glucose"
    *** source: 19274086-Fig-3d
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable-but unchanged irt Egf (4 hr)
    *** cells: SKMEL28 in BMLS "containing low-glucose"
    *** source: 19274086-Fig-3d
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable-but unchanged irt Egf (4 hr)
    *** cells: UACC903 in BMLS "containing low-glucose"
    *** source: 19274086-Fig-3d
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable-but unchanged irt Egf (4 hr)
    *** cells: A375 in BMLS "containing low-glucose"
    *** source: 19274086-Fig-3e
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable-but unchanged irt Egf (4 hr)
    *** cells: SKMEL28 in BMLS "containing low-glucose"
    *** source: 19274086-Fig-3e
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable-but unchanged irt Egf (4 hr)
    *** cells: UACC903 in BMLS "containing low-glucose"
    *** source: 19274086-Fig-3e

  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xEgfR(Y992F)"CA"
    *** cells: NIH3T3<xShp2(R465E)"DN"> in BMLS
    *** inhibited by: xEgfR(WT) [substitution]
    *** source: 14560030-Fig-8a

contradiction

  *** Erk2[Ab]IP Yphos[pYAb] is unchanged irt Egf (tnr)
    *** cells: HEPG2 in BMS
    *** source: 10446219-Fig-5c

Erk features

  *** xErk2[tAb]IP phos(TEY)[phosAb] is increased irt Egf (5 min)
    *** cells: NIH3T3<xErk2> in BMLS
    *** unaffected by: xErk2(L198A) [substitution]
    *** unaffected by: xErk2(L232A) [substitution]
    *** unaffected by: xErk2(Y261A) [substitution]
    *** unaffected by: xErk2(D319N) [substitution]
    *** source: 16051177-Fig-1b

  *** xErk2[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: COS7<xErk2> in BMLS
    *** inhibited by: xErk2(T185A/E186A/Y187A) [substitution]
    *** source: 18760948-Fig-2h
  *** xErk2[phosAb] phos(TEY)[phosAb] is increased irt Egf (times)
    *** cells: COS7<xErk2> in BMLS
    *** times: 0 5++ 15++ 30+ 45 min
    *** source: 18760948-Fig-2b
