================================
Direct Phosphorylation by Csnk1e
================================

  *** rApc(1484-1528)"R3"[CB] phos[WBMS] is increased by rCsnk1e
    *** cells: none
    *** enhanced by: rGsk3b [addition]
    *** source: 15327768-Fig-4a
  *** rApc(1211-2075)[32P] phos[32P-ATP] is detectable
    *** cells: none
    *** comment: reaction contains rCsnk1e
    *** source: 11425858-Fig-3b
  *** rApc(1211-2075)[CB] phos[WBMS] is increased by rCsnk1e
    *** cells: none
    *** source: 11425858-Fig-3c

===============================
Direct Phosphorylation by Gsk3b
===============================

enhanced by rAxin1--

  *** rApc(1211-2075)[32P] phos[32P-ATP] is increased by rAxin1
    *** cells: none
    *** comment: reaction mix contains rGsk3b
    *** inhibited by: rApc(959-1338) [substitution]
    *** source: 10698523-Fig-2a
  *** rApc(1211-2075)[32P] phos[32P-ATP] is increased by rAxin1
    *** cells: none
    *** comment: reaction mix contains rGsk3b
    *** inhibited by: rAxin1(298-506) [substitution]
    *** source: 10698523-Fig-3a

  requires rAxin1 RGS domain

  *** rApc(1211-2075)[32P] phos[32P-ATP] is unchanged by rAxin1(298-506)
    *** cells: none
    *** comment: reaction mix contains rGsk3b
    *** unaffected by: rApc(959-1338) [substitution]
    *** source: 10698523-Fig-2b
  *** rApc(1211-2075)[32P] phos[32P-ATP] is unchanged by rAxin1(298-832)
    *** cells: none
    *** comment: reaction mix contains rGsk3b
    *** unaffected by: rApc(959-1338) [substitution]
    *** source: 10698523-Fig-2c

enhanced by rCsnk1e--

  *** rApc(1484-1528)"R3"[CB] phos[WBMS] is increased by rGsk3b
    *** cells: none
    *** enhanced by: rCsnk1e [addition]
    *** source: 15327768-Fig-4a

enhanced by rCtnnb1--

  *** rApc(959-1338)[32P] phos[32P-ATP] is increased by rCtnnb1
    *** cells: none
    *** comment: reaction mix contains rGsk3b and rAxin1
    *** inhibited by: rCtnnb1(423-781) [substitution]
    *** source: 10698523-Fig-3b
  *** rApc(1211-2075)[32P] phos[32P-ATP] is increased by rCtnnb1
    *** cells: none
    *** comment: reaction mix contains rGsk3b and rAxin1
    *** inhibited by: rCtnnb1(423-781) [substitution]
    *** source: 10698523-Fig-3a

inhibited by Dvl1

  *** rApc(1211-2075)[32P] phos[32P-ATP] is increased by (rAxin1 + rGsk3b)
    *** cells: none
    *** inhibited by: rDvl1 [addition]
    *** source: 10330181-Fig-6c

=======================================
Increase in phosphorylation itpo xAxin1
=======================================

  *** Apc[Ab] phos[WBMS] is increased itpo xAxin1
    *** cells: Lcells in BMS
    *** source: 10698523-Fig-4b

=========================================
Increase in phosphorylation itpo xCsnk1e
=========================================

  *** xApc[tAb] phos[WBMS] is increased itpo xCsnk1e
    *** cells: COS<xDvl1> in BMS
    *** inhibited by: xCsnk1e(mnr)"KD" [substitution]
    *** source: 11425858-Fig-3a
