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Effect of chemicals on Erk Phosphorylation on TEY site
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  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (15 min)
    *** cells: 3Y1 in BMLS
    *** inhibited by: U0126 [pretreatment] no-bkg-control
    *** source: 15024089-Fig-4a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (15 min)
    *** cells: HEK293E in BMLS
    *** inhibited by: U0126 [pretreatment] no-bkg-control
    *** source: 15024089-Fig-4a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (1 hr)
    *** cells: REF52 in BMS
    *** inhibited by: U0126 [addition]
    *** source: 10480934-Fig-4b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: RAT2 in BMS
    *** inhibited by: U0126 [addition]
    *** source: 11297520-Fig-6b
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased irt Egf (5 min)
    *** cells: COS7 in BMLS
    *** inhibited by: U0126 [addition] no-bkg-control
    *** source: 10473620-Fig-4a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (30 min)
    *** cells: NR6<xEgfR> in BMLS
    *** inhibited by: U0126 [addition] no-bkg-control
    *** source: 14747473-Fig-6b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (5 min)
    *** cells: CHO<xEgfR><xInsR> in BMS
    *** inhibited by: U0126 [addition]
    *** source: 15192046-Fig-6
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (15 min)
    *** cells: mEFs<Jnk1~null><Jnk2~null> in BMLS
    *** inhibited by: U0126 [addition]
    *** source: 12110590-Fig-3d
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (1 hr)
    *** cells: REF52 in BMS
    *** inhibited by: PD98059 [addition]
    *** source: 10480934-Fig-4b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (5 min)
    *** cells: hUVECs in BMLS
    *** inhibited by: PD98059 [addition]
    *** source: 10671553-Fig-9a,9b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: RAT2 in BMS
    *** inhibited by: PD98059 [addition]
    *** source: 11297520-Fig-6b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: RAT2 in BMS
    *** inhibited by: PD98059 [addition]
    *** source: 11297520-Fig-6b
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased irt Egf (5 min)
    *** cells: COS7 in BMLS
    *** inhibited by: PD98059 [addition] no-bkg-control
    *** source: 10473620-Fig-4a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (5 min)
    *** cells: HEK293T in BMLS
    *** inhibited by: PD98059 [addition]
    *** source: 11598209-Fig-7b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (5 min)
    *** cells: mEFs in BMLS
    *** inhibited by: PD184352 [addition] no-bkg-control
    *** source: 11909979-Fig-3a
  *** xErk2[tAb]IP phos(TEY)[phosAb] is increased irt Egf (times)
    *** cells: COS1 in BMLS
    *** times: 0 2+ 5++ 10+++ min
    *** inhibited by: PP1 [addition]
    *** source: 15831486-Fig-1,2
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (5 min)
    *** cells: MDAMB468 in BMLS
    *** inhibited by: PP1 [addition]
    *** source: 14665621-Fig-8a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (15 min)
    *** cells: NIH3T3<xInsR> in BMLS
    *** partially inhibited by: PP1 [addition]
    *** source: 11046144-Fig-6b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (15 min)
    *** cells: mEFs<Jnk1~null><Jnk2~null> in BMLS
    *** unaffected by: PP1 [addition]
    *** source: 12110590-Fig-6a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (2 min)
    *** cells: A7R5 in BMLS
    *** unaffected by: PP2 [addition]
    *** source: 11907028-Fig-6a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: H197 in BMS
    *** unaffected by: Rottlerin [pretreatment]
    *** source: 10330161-Fig-2b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: H197 in BMS
    *** inhibited by: Wortmannin [pretreatment]
    *** source: 10330161-Fig-2d
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: H197 in BMS
    *** unaffected by: PDB [pretreatment]
    *** unaffected by: Go6976 [pretreatment]
    *** unaffected by: Rottlerin [pretreatment]
    *** inhibited by: Wortmannin [pretreatment]
    *** unaffected by: Chelerythrine [pretreatment]
    *** inhibited by: PD98059 [pretreatment]
    *** source: 10330161-Fig-3b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: PC12 in BMS
    *** unaffected by: Rottlerin [pretreatment]
    *** unaffected by: PDB [pretreatment]
    *** source: 10330161-Fig-5b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: NIH3T3 in BMS
    *** unaffected by: Rottlerin [pretreatment]
    *** source: 10330161-Fig-6a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (30 min)
    *** cells: HEK293<xTsc2> in BMLS
    *** inhibited by: U0126 [pretreatment] no-bkg-control
    *** unaffected by: Wortmannin [pretreatment] no-bkg-control
    *** source: 15851026-Fig-1b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: mESCs in BMLS
    *** inhibited by: PD98059 [pretreatment]
    *** source: 11018520-Fig-2c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: A431 in BMS
    *** bkg inhibited by: AG1478 [addition]
    *** bkg inhibited by: Compound-56 [addition]
    *** unaffected by: CGP77675 [addition]
    *** source: 17646016-Fig-3b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (3 min)
    *** cells: C3H10T12 in BMLS
    *** unaffected by: Bisindolylmaleimide-I [addition]
    *** unaffected by: Go6976 [addition]
    *** source: 11358964-Fig-3b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (20 min)
    *** cells: HELA in BMLS
    *** inhibited by: PD153035 [addition]
    *** source: 9790194-Fig-1d
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: MIMCD3 in BMLS
    *** inhibited by: PD98059 [pretreatment] no-bkg-control
    *** source: 1118451-Fig-1a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: MIMCD3 in BMLS
    *** inhibited by: U0126 [pretreatment] no-bkg-control
    *** source: 1118451-Fig-1b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (30 min)
    *** cells: 3Y1<xEgfR> in BMS
    *** inhibited by: 1Butanol [pretreatment]
    *** unaffected by: isoButanol [pretreatment]
    *** source: 11134345-Fig-8b
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: MDAMB468 in BMLS "treated with Egf for 5 hr"
    *** inhibited by: Gefitinib [pretreatment]
    *** inhibited by: AG1478 [pretreatment]
    *** unaffected by: AG490 [pretreatment]
    *** unaffected by: LY294002 [pretreatment]
    *** inhibited by: U0126 [pretreatment]
    *** source: 17909010-Fig-3a


Bisindolylmaleimide-I--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (5 min)
    *** cells: hUVECs in BMLS
    *** unaffected by: Bisindolylmaleimide-I [addition]
    *** source: 10671553-Fig-9a,9b

Forskolin--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (15 min)
    *** cells: HELA in BMLS
    *** unaffected by: Forskolin + IBMX [addition]
    *** source: 16581779-Fig-4c
  *** Erk1[Ab]IP IVKA(MBP)[32P-ATP] is increased irt Egf (10 min)
    *** cells: PC12 in BMLS
    *** unaffected by: Forskolin [addition]
    *** source: 9094716-Fig-2a

H89--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: RAT2 in BMS
    *** inhibited by: H89 [addition]
    *** source: 11297520-Fig-7a

LY294002--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (times)
    *** cells: COS in BMS
    *** times: 0 2+ 5+ 10+ 20+ 60+ min
    *** partially inhibited by: LY294002 [addition]
    *** source: 11259591-Fig-1a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (30 min)
    *** cells: NR6<xEgfR> in BMLS
    *** unaffected by: LY294002 [addition]
    *** source: 14747473-Fig-6d
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (times)
    *** cells: HC11 in BMLS "containing Ins"
    *** times: 0 7+ 15+ min
    *** unaffected by: LY294002 [addition]
    *** source: 16984645-Fig-4a
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is increased irt Egf (5 min)
    *** cells: VERO in BMLS
    *** inhibited by: LY294002 [addition] no-bkg-control
    *** source: 11134009-Fig-1b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (5 min)
    *** cells: VERO in BMLS
    *** inhibited by: LY294002 [addition] no-bkg-control
    *** source: 11134009-Fig-1a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (5 min)
    *** cells: COS7 in BMLS
    *** inhibited by: LY294002 [pretreatment]
    *** source: 10330169-Fig-1a

PD180970--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (5 min)
    *** cells: MDAMB468 in BMLS
    *** unaffected by: PD180970 [addition]
    *** source: 14665621-Fig-8c

PD184352--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (times)
    *** cells: RAT2 in BMS
    *** times: 0 2+ 5+ 10+ 20+ 40 min
    *** bkg inhibited by: PD184352 [addition]
    *** source: 11297520-Fig-6a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: RAT2 in BMS
    *** inhibited by: PD184352 [addition]
    *** source: 11297520-Fig-6b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: RAT2 in BMS
    *** inhibited by: PD184352 [addition]
    *** source: 11297520-Fig-6b

PMA--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (times)
    *** cells: COS7 in BMLS
    *** times: 0 5+ 10+ min
    *** unaffected by: PMA [addition]
    *** source: 11283245-Fig-1d
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (5 min)
    *** cells: COS7 in BMLS
    *** unaffected by: PMA [addition]
    *** source: 11283245-Fig-7b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (3 min)
    *** cells: C3H10T12 in BMLS "pretreated overnight with PMA"
    *** source: 11358964-Fig-3a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (3 min)
    *** cells: C3H10T12 in BMLS "pretreated overnight with PMA"
    *** unaffected by: Bisindolylmaleimide-I [addition]
    *** unaffected by: Go6976 [addition]
    *** source: 11358964-Fig-3b

Rapamycin--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: RAT2 in BMS
    *** unaffected by: Rapamycin [addition]
    *** source: 11297520-Fig-6b

Ro318220--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: RAT2 in BMS
    *** unaffected by: Ro318220 [addition]
    *** source: 11297520-Fig-6b

SB203580--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (15 min)
    *** cells: mEFs<Jnk1~null><Jnk2~null> in BMLS
    *** unaffected by: SB203580 [addition]
    *** source: 12110590-Fig-3d
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (5 min)
    *** cells: mEFs in BMLS
    *** unaffected by: SB203580 [addition] no-bkg-control
    *** source: 11909979-Fig-3a

SU416--

  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (5 min)
    *** cells: hUVECs in BMLS
    *** unaffected by: SU5416 [addition]
    *** source: 10671553-Fig-9a,9b


Wortmannin--

  *** Erk2[Ab]IP IVKA(EgfR)[32P-ATP] is increased irt Egf (10 min)
    *** cells: COS in BMLS
    *** unaffected by: Wortmannin [addition] no-bkg-control
    *** source: 9305638-Fig-4b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (5 min)
    *** cells: hUVECs in BMLS
    *** unaffected by: Wortmannin [addition]
    *** source: 10671553-Fig-9a,9b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (times)
    *** cells: COS in BMS
    *** times: 0 2+ 5+ 10+ 20+ 60+ min
    *** partially inhibited by: Wortmannin [addition]
    *** source: 11259591-Fig-1a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (10 min)
    *** cells: RAT2 in BMS
    *** unaffected by: Wortmannin [addition]
    *** source: 11297520-Fig-6b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (times)
    *** cells: HEK293 in BMLS
    *** times: 0 1+ 3++ 5++ 10+ 30+ min
    *** partially inhibited by: Wortmannin [addition]
    *** source: 16687399-Fig-2b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (times)
    *** cells: HEK293 in BMLS
    *** times: 0 1 3+ 4++ 5++ 7+++ 10++ 15+ 30+ min
    *** partially inhibited by: Wortmannin [addition]
    *** source: 16687399-Fig-2d
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is increased irt Egf (5 min)
    *** cells: VERO in BMLS
    *** inhibited by: Wortmannin [addition] no-bkg-control
    *** source: 11134009-Fig-1b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (5 min)
    *** cells: VERO in BMLS
    *** inhibited by: Wortmannin [addition] no-bkg-control
    *** source: 11134009-Fig-1a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Egf (5 min)
    *** cells: VERO in BMLS
    *** inhibited by: Wortmannin [addition] no-bkg-control
    *** source: 11134009-Fig-1c
