================================================
Acetylation does not require Atm Kinase Activity
================================================

  *** xAtm[Ab]IP acetyl(K3016)[AcAb] is increased irt Bleomycin (30 min)
    *** cells: GM5849<Atm~fmut><xAtm> in BMS
    *** unaffected by: xAtm(D2870A/N2875K/D2889A)"KD" [substitution]
    *** source: 17923702-Fig-4b

==========================
Acetylation requires Tip60
==========================

  *** Atm[Ab]IP acetyl[KAcAb] is increased irt Bleomycin (30 min)
    *** cells: HEK293T in BMS
    *** reqs: Tip60 [RNAi]
    *** source: 17923702-Fig-1b

=========================
Acetylation site is K3016
=========================

  *** xAtm[Ab]IP acetyl[KAcAb] is increased irt Bleomycin (30 min)
    *** cells: GM5849<Atm~fmut><xAtm> in BMS
    *** unaffected by: xAtm(K1772A/K1773A)"K2" [substitution]
    *** unaffected by: xAtm(K2204A/K2207A)"K6" [substitution]
    *** bkg inhibited by: xAtm(K3016A/K3018A)"K6" [substitution]
    *** source: 17923702-Fig-1b
  *** xAtm[Ab]IP acetyl(K3016)[AcAb] is increased irt Bleomycin (times)
    *** cells: GM5849<Atm~fmut><xAtm> in BMS
    *** times: 0 5+ 40+ 120+ min
    *** inhibited by: xAtm(K3016A) [substitution]
    *** source: 17923702-Fig-2b
  *** xAtm[Ab]IP acetyl[KAcAb] is increased irt Bleomycin (30 min)
    *** cells: GM5849<Atm~fmut><xAtm> in BMS
    *** inhibited by: xAtm(K3016A) [substitution]
    *** unaffected by: xAtm(K3018A) [substitution]
    *** source: 17923702-Fig-1d
  *** xAtm[Ab]IP acetyl[KAcAb] is increased irt Bleomycin (30 min)
    *** cells: GM5849<Atm~fmut><xAtm> in BMS
    *** inhibited by: xAtm(K3016T) [substitution]
    *** inhibited by: xAtm(K3016Q) [substitution]
    *** inhibited by: xAtm(K3016E) [substitution]
    *** inhibited by: xAtm(K3016A) [substitution]
    *** source: 17923702-Fig-1e
  *** xAtm[Ab]IP acetyl[KAcAb] is increased irt Bleomycin (tnr)
    *** cells: GM5849<Atm~fmut> in BMS
    *** inhibited by: xAtm(1-3032)"dFATC" [substitution]
    *** unaffected by: xAtm(chimera)"AtrFATC" [substitution]
    *** unaffected by: xAtm(chimera)"PrkdcFATC" [substitution]
    *** unaffected by: xAtm(chimera)"TrrapFATC" [substitution]
    *** source: 16603769-Fig-1b

============================================
Association with something with HAT activity
============================================

  *** Atm[Ab]IP IVHatAct(HistH4)[ELISA] is increased irt Bleomycin (30 min)
    *** cells: HELA<xTip60> in BMS
    *** source: 16603769-Fig-3d
  *** xAtm[Ab]IP IVHatAct(HistH4)[ELISA] is increased irt Bleomycin (30 min)
    *** cells: GM5849<Atm~fmut><xAtm> in BMS
    *** unaffected by: xAtm(K3016A) [substitution]
    *** source: 17923702-Fig-3a



