===========================
Phosphorylation on Tyrosine
===========================

IfngR2--

  *** Jak1[Ab]IP Yphos[pYAb] is increased irt Ifng (10 min)
    *** cells: 3112<xIfngR1> in BMS
    *** source: 7615558-Fig-3a
  *** Jak1[Ab]IP Yphos[pYAb] is increased irt Ifng (10 min)
    *** cells: CHOK1<xHlab7><xIfngR1><xIfngR2> in BMS
    *** reqs: xIfngR2 [omission]
    *** inhibited by: xIfngR2(1-285) [substitution]
    *** source: 7673114-Fig-4

Jak2--

  *** Jak1[Ab]IP Yphos[pYAb] is increased irt Ifng (15 min)
    *** cells: GAMMA2A<Jak2~null><xJak2> in BMS
    *** reqs: xJak2 [omission]
    *** inhibited by: xJak2(mnr)"KD" [substitution]
    *** source: 7537214-Fig-7a

Jak1 features

  *** xJak1[Ab]IP Yphos[pYAb] is increased irt Ifng (20 min)
    *** cells: U4A<Jak1~null><xJak1> in BMS
    *** inhibited by: xJak1(192-1125) [substitution]
    *** source: 12133952-Fig-4a


no extras

  *** Jak1[Ab]IP Yphos[pYAb] is increased irt Ifng (10 min)
    *** cells: HEPG2 in BMS
    *** source: 8272872-Fig-2c
  *** Jak1[Ab]IP Yphos[pYAb] is increased irt Ifng (15 min)
    *** cells: 2C4 in BMS
    *** source: 7537214-Fig-7a
  *** Jak1[Ab]IP Yphos[pYAb] is increased irt Ifng (15 min)
    *** cells: 2FTGH in BMS
    *** source: 7537214-Fig-1b
  *** Jak1[Ab]IP Yphos[pYAb] is increased irt Ifng (15 min)
    *** cells: HELA in BMS
    *** source: 7514165-Fig-4e
  *** xJak1[Ab]IP Yphos[pYAb] is increased irt Ifng (20 min)
    *** cells: U4A<Jak1~null><xJak1> in BMS
    *** source: 15935617-Fig-3b
  *** Jak1[Ab]IP Yphos[pYAb] is increased irt Ifng (times)
    *** cells: HELA in BMS
    *** times: 0 1+ 2+ 5+ min
    *** source: 7514165-Fig-2a
  *** Jak1[Ab]IP Yphos[pYAb] is unchanged irt Ifng (10 min)
    *** cells: L929<xIfngR1> in BMS
    *** comment: L929 cells are mouse and do not respond to hIfng
    *** source: 7615558-Fig-3a


===============
Kinase Activity
===============

IfngR2--

  *** Jak1[Ab]IP IVKA(peptide)[32P-ATP] is increased irt Ifng (10 min)
    *** cells: CHOK1<xHlab7><xIfngR1><xIfngR2> in BMS
    *** reqs: xIfngR2 [omission]
    *** inhibited by: xIfngR2(1-285) [substitution]
    *** source: 7673114-Fig-3

no extras

  *** Jak1[Ab]IP IVKA(auto)[32P-ATP] is detectable-but unchanged irt Ifng (tnr)
    *** cells: HELA in BMS
    *** source: 7615558-Fig-5
  *** Jak1[Ab]IP IVKA(auto)[pYAb] is detectable-but unchanged irt Ifng (tnr)
    *** cells: HELA in BMS
    *** source: 7615558-Fig-6

