=========================
Smad2 to TgfbR1 irt Tgfb1
=========================

  *** TgfbR1[Ab] copptby[WB] Smad2[Ab] is increased irt Tgfb1 (1 hr)
    *** cells: HEPG2 in BMS
    *** source: 12543979-Fig-2
  *** Smad2[Ab] copptby[WB] TgfbR1[Ab] is increased irt Tgfb1 (1 hr)
    *** cells: HEPG2 in BMS
    *** source: 12543979-Fig-2

====================================================
Coprecipitation with other members of TgfbR1 complex
====================================================

Smad3--

  *** xSmad2[35S] copptby[WB] xSmad3[35S] is increased itpo (xTgfbR1 + xTgfbR2)
    *** cells: COS in BMS
    *** source: 9311995-Fig-6a
  *** Smad2[Ab] copptby[WB] Smad3[Ab] is increased irt Tgfb1 (1 hr)
    *** cells: HEPG2 in BMS
    *** source: 12543979-Fig-2

Smurf2--

  *** xSmad2[Ab] copptby[WB] xSmurf2[tAb] is increased itpo xTgfbR1(mnr)"CA"
    *** cells: HEK293 in BMS
    *** inhibited by: xSmad2(mnr)"phos-mut" [substitution]
    *** source: 11389444-Fig-1b
  *** Smad2[Ab] snaggedby[WB] rSmurf2(244-434)[GST] is increased irt Tgfb1 (4 hr)
    *** cells: HACAT in BMS
    *** comment: snagged Smad2 is phosed(S465/S467)[phosAb]
    *** source: 11016919-Fig-4
  *** xSmad2[tAb] copptby[WB] xSmurf2[tAb] is increased itpo xTgfbR1(mnr)"CA"
    *** cells: HEK293 in BMS
    *** inhibited by: xSmad2(del(221-225))"del-PY" [substitution]
    *** source: 11389444-Fig-1d
  *** xSmad2[tAb] copptby[WB] xSmurf2[tAb] is increased itpo xTgfbR1(mnr)"CA"
    *** cells: HEK293 in BMS
    *** inhibited by: xSmad2(mnr)"phos-mut" [substitution]
    *** source: 11389444-Fig-1a
  *** xSmad2[tAb] copptby[WB] xSmurf2[tAb] is increased itpo xTgfbR1(mnr)"CA"
    *** cells: HEK293 in BMS
    *** unaffected by: xSmurf2(C716A)"CIA" [substitution]
    *** source: 11389444-Fig-1d

