================
Direct Activaton
================

S927

  *** rNfkb1(758-967)[phosAb] phos(S927)[phosAb] is increased by rIkk1
    *** cells: none
    *** inhibited by: rNfkb1((758-967)/S927A) [substitution]
    *** unaffected by: rNfkb1((758-967)/S932A) [substitution]
    *** source: 12482991-Fig-4c
  *** rNfkb1(758-967)[phosAb] phos(S927)[phosAb] is increased by rIkk1
    *** cells: none
    *** inhibited by: rNfkb1(758-967/S927A) [substitution]
    *** source: 11297557-Fig-6c

S932

  *** rNfkb1(758-967)[phosAb] phos(S932)[phosAb] is increased by rIkk1
    *** cells: none
    *** inhibited by: rNfkb1((758-967)/S932A) [substitution]
    *** unaffected by: rNfkb1((758-967)/S927A) [substitution]
    *** source: 12482991-Fig-4c


==========================
SemiDirect Phosphorylation
==========================

  *** rNfkb1(436-968)"delN"[32P] phos[32P-ATP] is increased by xIkk1[tAb]IP
    *** cells: none
    *** IPfrom: HELA<xIkk1> in BMS
    *** partially inhibited by: rNfkb1(436-968/S921A/S923A/S932A)"delN" [substitution]
    *** source: 10469655-Fig-9a
  *** rNfkb1[32P] phos[32P-ATP] is increased by xIkk1[tAb]IP
    *** cells: none
    *** IPfrom: HELA<xIkk1> in BMS
    *** comment: enhanced by treatment of cells with Tnf for 5 min
    *** source: 10469655-Fig-4a
  *** rNfkb1[32P] phos[32P-ATP] is increased by xIkk1[tAb]IP
    *** cells: none
    *** IPfrom: HELA<xIkk1> in BMS
    *** comment: enhanced by treatment of cells with Tnf for 5 min
    *** source: 10469655-Fig-4b
  *** rNfkb1[32P] phos[32P-ATP] is increased by xIkk1[tAb]IP
    *** cells: none
    *** IPfrom: HELA<xIkk1> in BMS
    *** inhibited by: rNfkb1(1-433) [substitution]
    *** partially inhibited by: rNfkb1(468-968) [substitution]
    *** inhibited by: rNfkb1(202-818) [substitution]
    *** partially inhibited by: rNfkb1(818-968) [substitution]
    *** source: 10469655-Fig-5b
  *** rNfkb1[32P] phos[32P-ATP] is increased by xIkk1[tAb]IP
    *** cells: none
    *** IPfrom: HELA<xIkk1> in BMS
    *** unaffected by: rNfkb1(1-936)"delC1" [substitution]
    *** partially inhibited by: rNfkb1(1-920)"delC2" [substitution]
    *** partially inhibited by: rNfkb1(1-902)"delC3" [substitution]
    *** partially inhibited by: rNfkb1(1-891)"delC4" [substitution]
    *** inhibited by: rNfkb1(1-850)"delC5" [substitution]
    *** source: 10469655-Fig-5c

===================
Protein Association
===================

  *** xIkk1[tAb] copptby[WB] xNfkb1[tAb] is detectable
    *** cells: HEK293<xIkk1><xNfkb1> in BMS
    *** inhibited by: xNfkb1(1-850)"delC5" [substitution]
    *** inhibited by: xNfkb1(1-433) [substitution]
    *** unaffected by: rNfkb1(mnr)"delN" [substitution]
    *** source: 10469655-Fig-6

