==========
EgfR coppt
==========

  *** EgfR[Ab] copptby[WB] Cbl[Ab] is increased irt Egf (5 min)
    *** cells: MDA in BMS
    *** source: 11894095(D)
  *** Cbl[Ab] copptby[WB] EgfR[Ab] is increased irt Egf (10 min)
    *** cells: 16E6P in BMS "Egf deprived"
    *** source: 8662998-Fig-4
  *** EgfR[Ab] copptby[WB] Cbl[Ab] is increased irt Egf (times)
    *** cells: PC12 in BMLS
    *** times: 0 1++ 5+ 15 min
    *** source: 8550620-Fig-3d
  *** EgfR[Ab] copptby[WB] xCbl[tAb] is increased irt Egf (times)
    *** cells: HEK293 in BMLS
    *** times: 0 3+ 10+ 30 60 min
    *** source: 10531381(D)
  *** Cbl[Ab] copptby[WB] EgfR[Ab] is increased irt Egf (15 min)
    *** cells: COS7 in BMLS
    *** source: 15465819(D)
  *** xCbl[Ab] copptby[WB] EgfR[Ab] is increased irt Egf (15 min)
    *** cells: COS7 in BMLS
    *** source: 15465819(D)
  *** Cbl[Ab] copptby[WB] EgfR[Ab] is increased irt Egf (times)
    *** cells: BE2C in BMLS
    *** times: 0 5++ 30+ 60+ min
    *** source: 17182860(D)
  *** Cbl[Ab] copptby[WB] EgfR[Ab] is increased irt Egf (times)
    *** cells: COS7 in BMLS
    *** times: 0 1+ 10+ 30+ 60++ min
    *** source: 17182860(D)
  *** Cbl[Ab] copptby[WB] EgfR[Ab] is increased irt Egf (times)
    *** cells: mEFs<Plcg1~null><xPlcg1> in BMLS
    *** times: 0 5+ 15+ min
    *** source: 12061819-Fig-3b

=====
Yphos
=====

  *** Cbl[Ab]IP Yphos[pYAb] is increased irt Egf (10 min)
    *** cells: 76N in BMS "Egf deprived"
    *** source: 8662998-Fig-3
  *** Cbl[Ab]IP Yphos[pYAb] is increased irt Egf (times)
    *** cells: 16E6P in BMS "Egf deprived"
    *** times: 0 1++ 2+++ 5+ 15++ 60+ min
    *** source: 8662998-Fig-1a,2,4
  *** Cbl[MS] Yphos[pYAb-ppt] is increased irt Egf (5 min)
    *** cells: HELA in BMLS
    *** comment: ppt Cbl was predicted to be phosed on Y674 [MS]
    *** source: 11687594-Table-1,2
  *** Cbl[Ab]IP Yphos[pYAb] is increased irt Egf (times)
    *** cells: T47D in BMLS
    *** times: 0 1+ 2+ 5+ 10+ 15+ min
    *** inhibited by: PP1 [addition]
    *** source: 11994282(D)
  *** Cbl[MS] Yphos[pYAb-ppt] is increased irt Egf (times)
    *** cells: HELA in BMLS
    *** times: 0 1+++ 5+++ 10++ 20+ min
    *** source: 15314609(D)
  *** Cbl[Ab] Yphos[pYAb-ppt] is increased irt Egf (times)
    *** cells: HELA in BMLS
    *** times: 0 1+++ 5+++ 10++ 20+ min
    *** source: 15314609(D)
  *** Cbl[Ab]IP Yphos[pYAb] is increased irt Egf (times)
    *** cells: PC12 in BMLS
    *** times: 0 1++ 5+ 15 min
    *** source: 8550620-Fig-3c
  *** Cbl[Ab] Yphos[pYAb-ppt] is increased irt Egf (times)
    *** cells: PC12 in BMLS
    *** times: 0 1++ 5+ 15 min
    *** source: 8550620-Fig-3b
  *** Cbl[MS] Yphos[pYAb-ppt] is increased irt Egf (5 min)
    *** cells: HELA in BMLS
    *** source: 10618391-Table-1
  *** Cbl[Ab]IP Yphos[pYAb] is increased irt Egf (times)
    *** cells: mEFs<Plcg1~null><xPlcg1> in BMLS
    *** times: 0 5+ 15+ min
    *** unaffected by: xPlcg1(del(SH3)) [substitution]
    *** source: 12061819-Fig-4a,4b
  *** Cbl[Ab]IP Yphos[pYAb] is increased irt Egf (times)
    *** cells: RAT1<xInsR> in BMLS
    *** times: 0 1+++ 5++ 10+ 20+ min
    *** source: 9348226-Fig-3a
  *** Cbl[Ab]IP Yphos[pYAb] is increased irt Egf (times)
    *** cells: HEK293 in BMLS
    *** times: 0 1++ 2++ 5+ 10+ min
    *** partially inhibited by: Forskolin [addition]
    *** source: 12606547-Fig-6a
  *** Cbl[Ab]IP Yphos[pYAb] is increased irt Egf (times)
    *** cells: NIH3T3<xInsR> in BMS
    *** times: 0 1++ 2++ 5+ 10+ min
    *** partially inhibited by: Forskolin [addition]
    *** source: 12606547-Fig-6b
  *** Crk[Ab]IP Yphos[pYAb] is increased irt Egf (times)
    *** cells: PC12 in BMLS
    *** times: 0 2++ 5++ 15 30 60 min
    *** source: 11278445-Fig-5a
  *** xCbl[Ab]IP Yphos[pYAb] is detectable-but unchanged irt Egf (10 min)
    *** cells: HEK293T<xArhGef7><xCbl> in BMLS
    *** source: 16407834-Fig-3e


=======================================================
Coprecipitation with other members of the EgfR complex
=======================================================

ArhGef7--

  *** xCbl[tAb] copptby[WB] ArhGef7[Ab] is detectable-but unchanged irt Egf (10 min)
    *** cells: HEK293T<xCbl> in BMS
    *** inhibited by: xCbl(R829A) [substitution]
    *** source: 16407834-Fig-3b
  *** xCbl[tAb] copptby[WB] xArhGef7[tAb] is decreased irt Egf (10 min)
    *** cells: HEK293T<xArhGef7><xCbl> in BMS
    *** source: 16407834-Fig-3a


Cbl--

  *** Cbl[Ab] copptby[WB] ArhGef7[Ab] is increased irt Egf (10 min)
    *** cells: HEK293T in BMS
    *** source: 16407834-Fig-3b

Cin85--

  *** Cbl[Ab] copptby[WB] Cin85[Ab] is increased irt Egf (5 min)
    *** cells: HELA in BMS
    *** source: 11894095-Fig-1b
  *** Cbl[Ab] copptby[WB] Cin85[Ab] is increased irt Egf (5 min)
    *** cells: HELA in BMS
    *** source: 11894095-Fig-2d
  *** Cbl[Ab] copptby[WB] Cin85[Ab] is increased irt Egf (5 min)
    *** cells: MDA in BMS
    *** source: 11894095-Fig-2d
  *** Cbl[Ab] copptby[WB] xCin85[tAb] is increased irt Egf (5 min)
    *** cells: HEK293T<xEndA1> in BMS
    *** source: 11894095-Fig-2b

Crk--

  *** Cbl[Ab] copptby[WB] Crk[Ab] is increased irt Egf (times)
    *** cells: RAT1<xInsR> in BMLS
    *** times: 0 1+++ 5++ 10+ 20+ min
    *** source: 9348226-Fig-3b
  *** Cbl[Ab] copptby[WB] Crk[Ab] is increased irt Egf (times)
    *** cells: PC12 in BMLS
    *** times: 0 2+++ 5+++ 15++ 30+ 60+ min
    *** source: 11278445-Fig-5c

CrkL--

  *** Cbl[Ab] copptby[WB] CrkL[Ab] is increased irt Egf (times)
    *** cells: PC12 in BMLS
    *** times: 0 5+ 10+ min
    *** source: 11466412-Fig-4c
  *** Cbl[Ab] copptby[WB] CrkL[Ab] is increased irt Egf (10 min)
    *** cells: 16E6P in BMS "Egf deprived"
    *** source: 8662998-Fig-4

EndA1--

  *** Cbl[Ab] copptby[WB] EndA1[Ab] is increased irt Egf (5 min)
    *** cells: HELA in BMS
    *** source: 11894095-Fig-2d
  *** Cbl[Ab] copptby[WB] EndA1[Ab] is increased irt Egf (5 min)
    *** cells: MDA in BMS
    *** source: 11894095-Fig-2d

Grb2--

  *** Cbl[Ab] copptby[WB] Grb2[Ab] is increased irt Egf (10 min)
    *** cells: 16E6P in BMS "Egf deprived"
    *** source: 8662998-Fig-4

Pi3k--

  *** Cbl[Ab] copptby[WB] Pik3rs[Ab] is increased irt Egf (10 min)
    *** cells: 16E6P in BMS "Egf deprived"
    *** source: 8662998-Fig-4

Plcg1--

  *** Cbl[Ab] copptby[WB] Plcg1[Ab] is increased irt Egf (times)
    *** cells: NIH3T3<xEgfR> in BMLS
    *** times: 0 5+ 15++ min
    *** source: 12061819-Fig-2
  *** Cbl[Ab] copptby[WB] xPlcg1[Ab] is increased irt Egf (times)
    *** cells: mEFs<Plcg1~null><xPlcg1> in BMLS
    *** times: 0 5+ 15+ min
    *** inhibited by: xPlcg1(del(SH3)) [substitution]
    *** source: 12061819-Fig-3a,5


===========
Degradation
===========

  *** xCbl[tAb] prot-exp[WB] is decreased irt Egf (times)
    *** cells: HEK293T<xArhGef7><xCbl> in BMLS
    *** times: 0++ 5++ 10+ 30+ 60+ min
    *** source: 16407834-Fig-3c
