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Transcription
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Stat6-- ???

  *** Bclxl-gene mRNA[Northern] is increased irt IL4 (7 hr)
    *** cells: mSpBCs<Cd45~pos> in BMS "treated with anti-IgM"
    *** bkg reqs: Stat6 [KO]
    *** source: 12023955-Fig-3b
  *** Bclxl-gene mRNA[Northern] is increased irt IL4 (times)
    *** cells: mSpCs in BMS "treated with anti-Cd3 for 48 hr"
    *** times: 0 24+ 48+ hr
    *** does not req: Stat6 [KO]
    *** source: 10843732-Fig-6

Chemicals

  *** Bclxl-gene mRNA[Northern] is increased irt IL4 (6 hr)
    *** cells: CTLL2 in BMS "IL2-deprived"
    *** unaffected by: Rapamycin [cotreatment]
    *** unaffected by: Wortmannin [cotreatment]
    *** source: 10843732-Fig-4
  *** Bclxl-gene mRNA[Northern] is increased irt IL4 (24 hr)
    *** cells: mSpCs in BMS "treated with anti-Cd3 for 48 hr"
    *** unaffected by: Rapamycin [cotreatment]
    *** unaffected by: Wortmannin [cotreatment]
    *** source: 10843732-Fig-6
  *** Bclxl-gene mRNA[Northern] is increased irt IL4 (48 hr)
    *** cells: mSpCs in BMS "treated with anti-Cd3 for 48 hr"
    *** enhanced by: Rapamycin [cotreatment]
    *** unaffected by: Wortmannin [cotreatment]
    *** source: 10843732-Fig-6

Requirement for Protein synthesis

  *** Bclxl-gene mRNA[Northern] is increased irt IL4 (7 hr)
    *** cells: mSpBCs<Cd45~pos> in BMS "treated with anti-IgM"
    *** unaffected by: CHX [pretreatment]
    *** source: 12023955-Fig-3c

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Translation
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  *** Bclxl[Ab] prot-exp[WB] is detectable-but unchanged irt IL4 (17 hr)
    *** cells: mLCs<IgM~neg><IgG~neg> in BMS
    *** does not req: Stat6 [KO]
    *** does not req: Irs2 [KO]
    *** does not req: Irs2 or Stat6 [DKO]
    *** source: 11739727-Fig-5b
  *** Bclxl[Ab] prot-exp[WB] is increased irt IL4 (48 hr)
    *** cells: mSpBCs<Cd45~pos> in BMS
    *** enhanced by: anti-IgM [cotreatment]
    *** partially reqs: Stat6 [KO]
    *** source: 12023955-Fig-3a

