=====================================================
RasGrf1 is directly phosphorylated on tyrosine by Src
=====================================================

  *** rRasGrf1[32P] phos[32P-ATP] is increased by rSrc
    *** cells: none
    *** source: 10681520-Fig-5a
  *** rRasGrf1[pYAb] Yphos[pYAb] is increased by rSrc
    *** cells: none
    *** source: 10681520-Fig-5b

=========================
Yphos in the presence of
=========================

  *** xRasGrf1[tAb]IP Yphos[pYAb] is increased itpo xSrc(mnr)"vSrc"
    *** cells: HEK293 in BMS
    *** source: 10681520-Fig-1a,1b
  *** xRasGrf1[tAb]IP Yphos[pYAb] is increased itpo xSrc
    *** cells: HEK293<xRasGrf1> in BMLS
    *** source: 16481401-Fig-5d

==========================================================================
RasGrf1 Gef-activity on Rac1 is increased in the presence of activated Src
==========================================================================

  *** xRasGrf1[tAb]IP IVGefA(Rac1)[3H-GDP] is increased itpo xSrc(mnr)"vSrc"
    *** cells: HEK293 in BMLS
    *** source: 10681520-Fig-2a,2b
  *** xRasGrf1[tAb]IP IVGefA(Rac1)[3H-GDP] is increased itpo xSrc(mnr)"vSrc"
    *** cells: HEK293 in BMLS
    *** source: 10681520-Fig-3

============================================================
RasGrf1 phosphorylated by Src is not a Gef for Cdc42 or Rhoa
============================================================

  *** xRasGrf1[tAb]IP IVGefA(Cdc42)[3H-GDP] is unchanged itpo xSrc(mnr)"vSrc"
    *** cells: HEK293 in BMLS
    *** source: 10681520-Fig-3
  *** xRasGrf1[tAb]IP IVGefA(Rhoa)[3H-GDP] is unchanged itpo xSrc(mnr)"vSrc"
    *** cells: HEK293 in BMLS
    *** source: 10681520-Fig-3

  *** xRasGrf1[tAb]IP IVGefA(Hras)[3H-GDP] is detectable
    *** cells: HEK293 in BMLS
    *** unaffected by: xSrc(mnr)"vSrc" [addition]
    *** source: 10681520-Fig-4

