================================
Phosphorylation on S957 and S966
================================

not Atm--

  *** Smc1a[phosAb] phos(S966)[phosAb] is increased irt UV (2 hr)
    *** cells: GM9607<Atm~fmut> in BMS
    *** source: 11877376-Fig-3b
  *** Smc1a[phosAb] phos(S957)[phosAb] is increased irt UV (2 hr)
    *** cells: GM9607<Atm~fmut> in BMS
    *** source: 11877376-Fig-3b
  *** Smc1a[phosAb] phos(S957)[phosAb] is increased irt UV (90 min)
    *** cells: GM1588<Atm~fmut> in BMS
    *** comment: signal is similar to that in cells from normal fibros
    *** source: 16087684-Fig-2b
  *** Smc1a[phosAb] phos(S966)[phosAb] is increased irt UV (1 hr)
    *** cells: hFibros<Atm~fmut> in BMS
    *** source: 16327781-Fig-1a

Atr--

  *** Smc1a[phosAb] phos(S957)[phosAb] is increased irt UV (times)
    *** cells: DK0061<Atr~fmut> in BMS
    *** times: 0 30+ 90+ min
    *** comment: signal is significantly lower than that in cells from normal lymphoblasts
    *** source: 16087684-Fig-2b
  *** Smc1a[phosAb] phos(S966)[phosAb] is unchanged irt UV (1 hr)
    *** cells: hFibros<Atr~fmut> in BMS
    *** source: 16327781-Fig-1a

not Mdc1--

  *** Smc1a[phosAb] phos(S966)[phosAb] is increased irt UV (3 hr)
    *** cells: NotReported in BMS
    *** does not req: Mdc1 [RNAi]
    *** source: 12607005-Fig-5e

Rad50--

  *** Smc1a[phosAb] phos(S957)[phosAb] is increased irt UV (times)
    *** cells: HCT116 in BMS
    *** times: 0 30+ 90+ min
    *** reqs: Rad50 [RNAi]
    *** comment: Rad50 KD also causes loss of Nbs1 or Mre11 prot-exp
    *** source: 16087684-Fig-2a
  *** Smc1a[phosAb] phos(S957)[phosAb] is increased irt UV (times)
    *** cells: HEK293T in BMS
    *** times: 0 30+ 90++ min
    *** partially reqs: Rad50 [RNAi]
    *** comment: Rad50 KD also causes partial loss of Nbs1 and total loss Mre11 prot-exp
    *** source: 16087684-Fig-2a


no extras

  *** Smc1a[phosAb] phos(S957)[phosAb] is increased irt UV (2 hr)
    *** cells: GM637 in BMS
    *** source: 11877376-Fig-3b
  *** Smc1a[phosAb] phos(S966)[phosAb] is increased irt UV (2 hr)
    *** cells: GM637 in BMS
    *** source: 11877376-Fig-3b
  *** Smc1a[phosAb] phos(S957)[phosAb] is increased irt UV (90 min)
    *** cells: hFibros in BMS
    *** source: 16087684-Fig-2b
  *** Smc1a[phosAb] phos(S957)[phosAb] is increased irt UV (times)
    *** cells: DK0063 in BMS
    *** times: 0 30+ 90+ min
    *** source: 16087684-Fig-2b
  *** Smc1a[phosAb] phos(S957)[phosAb] is increased irt UV (3 hr)
    *** cells: GM637 in BMS
    *** source: 15175241-Fig-S1a
  *** Smc1a[phosAb] phos(S957)[phosAb] is increased irt UV (3 hr)
    *** cells: GM9607<Atm~fmut> in BMS
    *** source: 15175241-Fig-S1a
  *** Smc1a[phosAb] phos(S966)[phosAb] is increased irt UV (1 hr)
    *** cells: HELA in BMS
    *** source: 16327781-Fig-1a
