==========
EgfR coppt
==========

  *** Grb2[Ab] copptby[WB] xEgfR[Ab] is increased irt Egf (3 min)
    *** cells: NIH3T3<xEgfR> in BMLS
    *** inhibited by: xEgfR(del(1084-1210)) [substitution]
    *** source: 7518560(D)
  *** Grb2[Ab] copptby[WB] EgfR[Ab] is increased irt Egf (2 min)
    *** cells: MDAMB361 in BMLS
    *** source: 11297548(D)
  *** Grb2[Ab] copptby[WB] EgfR[Ab] is increased irt Egf (2 min)
    *** cells: A7R5 in BMLS
    *** source: 11907028(D)
  *** Grb2[Ab] copptby[WB] EgfR[Ab] is increased irt Egf (10 min)
    *** cells: 16E6P in BMS "Egf deprived"
    *** source: 8662998-Fig-4
  *** Grb2[Ab] copptby[WB] xEgfR[Ab] is increased irt Egf (2 min)
    *** cells: CHO in BMLS
    *** source: 7527043-Fig-2
  *** Grb2[Ab] copptby[WB] xEgfR[Ab] is increased irt Egf (times)
    *** cells: CHO in BMLS
    *** times: 0 1++ 2+++ 5++ 10+ min
    *** source: 7527043-Fig-3
  *** Grb2[Ab] copptby[WB] xEgfR[Ab] is increased irt Egf (2 min)
    *** cells: CHO in BMLS
    *** inhibited by: xEgfR(Y1092F/Y1110F/Y1172A/Y1197F) [substitution]
    *** inhibited by: xEgfR(Y1016F/Y1092F/Y1110F/Y1172A) [substitution]
    *** unaffected by: xEgfR(Y1016F/Y1110F/Y1172A/Y1197F) [substitution]
    *** partially inhibited by: xEgfR(Y1016F/Y1092F/Y1172A/Y1197F) [substitution]
    *** partially inhibited by: xEgfR(Y1016F/Y1092F/Y1110F/Y1197F) [substitution]
    *** inhibited by: xEgfR(Y1016F/Y1092F/Y1110F/Y1172A/Y1197F) [substitution]
    *** source: 7527043-Fig-4
  *** Grb2[Ab] copptby[WB] EgfR[Ab] is increased irt Egf (times)
    *** cells: RAT1 in BMLS
    *** times: 0 1++ 2++ 5++ 10++ 20++ min
    *** source: 7798267-Fig-3b
  *** xGrb2[tAb] copptby[WB] EgfR[Ab] is increased irt Egf (30 min)
    *** cells: COS1 in BMS
    *** source: 14498832-Fig-6
  *** Grb2[Ab] copptby[WB] xEgfR[Ab] is increased irt Egf (10 min)
    *** cells: NIH3T3<xErbb2> in BMLS
    *** source: 9710588-Fig-3a
  *** Grb2[Ab] copptby[WB] xEgfR[Ab] is increased irt Egf (10 min)
    *** cells: NIH3T3<xErbb3> in BMLS
    *** source: 9710588-Fig-3a
  *** Grb2[Ab] copptby[WB] xEgfR[Ab] is increased irt Egf (10 min)
    *** cells: NIH3T3<xErbb4> in BMLS
    *** source: 9710588-Fig-3a
  *** Grb2[Ab] copptby[WB] EgfR[Ab] is increased irt Egf (2 min)
    *** cells: HER14 in BMLS
    *** source: 1322798-Fig-3
  -------------------------------------------------------------------------
  *** EgfR[phosAb] copptby[WB] Grb2[Ab] is increased irt Egf (times)
    *** cells: CHO<xEgfR><xInsR> in BMS
    *** times: 0 2+ 5+ 15+ min
    *** comment: only EgfR phosed on Y0192 was examined
    *** source: 15192046-Fig-7
  *** EgfR[Ab] copptby[WB] Grb2[Ab] is increased irt Egf (10 min)
    *** cells: MIMCD3 in BMLS
    *** unaffected by: U0126 [addition]
    *** source: 11896055(D)
  *** xEgfR[Ab] copptby[WB] Grb2[Ab] is increased irt Egf (15 min)
    *** cells: NIH3T3<xEgfR> in BMS
    *** inhibited by: xEgfR(Y1016F/Y1092F/Y1110F/Y1172F/Y1197F) [substitution]
    *** source: 8626525-Fig-4a
  *** EgfR[Ab] copptby[WB] Grb2[Ab] is increased irt Egf (5 min)
    *** cells: VERO in BMLS
    *** partially inhibited by: Wortmannin [addition] no-bkg-control
    *** partially inhibited by: LY294002 [addition] no-bkg-control
    *** source: 11134009-Fig-5a
  *** EgfR[Ab] copptby[WB] Grb2[Ab] is increased irt Egf (5 min)
    *** cells: COS7 in BMLS
    *** source: 10330169-Fig-3d
  *** EgfR[Ab] snaggedby[WB] rGrb2[GST] is increased irt Egf (2 min)
    *** cells: HER14 in BMLS
    *** unaffected by: rGrb2(mnr)"SH2" [substitution]
    *** source: 1322798-Fig-5


Yphos???

  *** Grb2[Ab] Yphos[pYAb-ppt] is increased irt Egf (times)
    *** cells: HELA in BMLS
    *** times: 0 1++ 5+ 10+ 20 min
    *** source: 15314609-Fig-2
  *** Grb2[Ab]IP phos[32Pi] is unchanged irt Egf (2 min)
    *** cells: HER14 in BMLS
    *** source: 1322798-Fig-6



=======================================
copptby[WB] other EgfR binding proteins
=======================================

Cbl--

  *** Grb2[Ab] copptby[WB] Cbl[Ab] is increased irt Egf (10 min)
    *** cells: 16E6P in BMS "Egf deprived"
    *** source: 8662998-Fig-4

Gab1

  *** Grb2[Ab] copptby[WB] Gab1[Ab] is increased irt Egf (10 min)
    *** cells: PC12 in BMLS
    *** source: 11353842-Fig-2d

Shc1--

  *** Grb2[Ab] copptby[WB] Shc1[Ab] is increased irt Egf (10 min)
    *** cells: 16E6P in BMS "Egf deprived"
    *** source: 8662998-Fig-4
  *** Grb2[Ab] copptby[WB] Shc1[Ab] is increased irt Egf (times)
    *** cells: RAT1<xInsR> in BMLS
    *** times: 0 1++ 10+ 30+ 60 120 min
    *** unaffected by: PD98059 [addition]
    *** source: 7592690-Fig-3d
  *** Grb2[Ab] copptby[WB] Shc1[Ab] is increased irt Egf (times)
    *** cells: RAT1 in BMLS
    *** times: 0 1+ 2+ 5+ 10+ 20+ min
    *** source: 7798267-Fig-3a
  *** Grb2[Ab] copptby[WB] xShc1p52[Ab] is increased irt Egf (5 min)
    *** cells: COS1 in BMLS
    *** inhibited by: xShc1(Y349F) [substitution]
    *** inhibited by: xShc1(Y350F) [substitution]
    *** inhibited by: xShc1(Y349F/Y350F) [substitution]
    *** source: 8939605-Fig-8c
  *** Grb2[Ab] copptby[WB] xShc1p52[Ab] is increased irt Egf (5 min)
    *** cells: COS1 in BMLS
    *** inhibited by: xShc1(Y349F/Y350F) [substitution]
    *** unaffected by: xShc1(Y427F) [substitution]
    *** source: 8939605-Fig-7c
  *** Grb2[Ab] copptby[WB] xShc1[Ab] is increased irt Egf (5 min)
    *** cells: NIH3T3<xEgfR><xShc1> in BMLS
    *** inhibited by: xShc1(Y427F) [substitution]
    *** unaffected by: xShc1(Y349F/Y350F) [substitution]
    *** source: 9121430-Fig-6d
  *** Grb2[Ab] copptby[WB] Shc1[Ab] is increased irt Egf (1 min)
    *** cells: HEK293 in BMS
    *** source: 8647288-Fig-4c
  *** Grb2[Ab] copptby[WB] (xShc1p52[Ab] + xShc1p46[Ab]) is increased irt Egf (5 min)
    *** cells: COS1 in BMS
    *** source: 9049300(D)
  *** Grb2[Ab] copptby[WB] xShc1p66[Ab] is increased irt Egf (5 min)
    *** cells: COS1 in BMS
    *** source: 9049300(D)
  *** Grb2[Ab] copptby[WB] Shc1[Ab] is increased irt Egf (times)
    *** cells: CCL39<xEgfR> in BMS
    *** times: 0 5++ 10++ 20+ 30+ 60+ min
    *** source: 9733714-Fig-3b
  *** Grb2[Ab] copptby[WB] Shc1[Ab] is increased irt Egf (5 min)
    *** cells: COS7 in BMLS
    *** unaffected by: LY294002 [pretreatment]
    *** source: 10330169-Fig-4c

Sos1--

  *** Grb2[Ab] copptby[WB] Sos1[Ab] is detectable-but unchanged irt Egf (5 min)
    *** cells: COS7 in BMLS
    *** unaffected by: LY294002 [pretreatment]
    *** source: 10330169-Fig-4c

Tnk2--

  *** Grb2[Ab] copptby[WB] xTnk2[Ab] is increased irt Egf (1 min)
    *** cells: HEK293 in BMS
    *** source: 8647288-Fig-4b

