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Transcription
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  *** Cdkn1a-gene mRNA[RTPCR] is increased irt UV (12 hr)
    *** cells: MCF7 in BMS
    *** source: 11030628-Fig-5h

contradiction

  *** Cdkn1a-gene promo-reporter[Luc] is unchanged irt UV (24 hr)
    *** cells: MCF7 in BMS
    *** source: 11780126-Fig-5b

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Translation
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increase reqs Pin1--

  *** Cdkn1a[Ab] prot-exp[WB] is increased irt UV (12 hr)
    *** cells: HCT116 in BMS "treated with Nutlin3a"
    *** reqs: Pin1 [RNAi]
    *** source: 17906639-Fig-1c
  *** Cdkn1a[Ab] prot-exp[WB] is increased irt UV (16 hr)
    *** cells: mEFs in BMS
    *** partially reqs: Pin1 [KO]
    *** source: 12397361-Fig-S2d
  *** Cdkn1a[Ab] prot-exp[WB] is increased irt UV (tnr)
    *** cells: U2OS in BMS
    *** enhanced by: xPin1 [addition]
    *** source: 12397361-Fig-3a

  *** Cdkn1a[Ab] prot-exp[WB] is increased irt UV (12 hr)
    *** cells: U2OS in BMS
    *** comment: increase correlates with the increase in Tp53 prot-exp
    *** source: 17906639-Fig-S1a
  *** Cdkn1a[Ab] prot-exp[WB] is increased irt UV (48 hr)
    *** cells: MCF7 in BMS
    *** source: 11030628-Fig-5g


decrease

  *** Cdkn1a[Ab] prot-exp[WB] is decreased irt UV (12 hr)
    *** cells: MCF7 in BMS
    *** source: 11780126-Fig-5a


Atm--  ???

  *** Cdkn1a[Ab] prot-exp[WB] is decreased irt UV (90 min)
    *** cells: GM1588<Atm~fmut> in BMS
    *** comment: signal is similar to that in cells from normal fibros
    *** source: 16087684-Fig-4b

Atr--  ???

  *** Cdkn1a[Ab] prot-exp[WB] is decreased irt UV (times)
    *** cells: DK0061<Atr~fmut> in BMS
    *** times: 0++ 30+ 90 min
    *** comment: decrease is slightly less than that in cells from normal lymphoblasts
    *** source: 16087684-Fig-4b

Rad50-- ???

  *** Cdkn1a[Ab] prot-exp[WB] is decreased irt UV (times)
    *** cells: HCT116 in BMS
    *** times: 0++ 30+ 90 min
    *** does not req: Rad50 [RNAi]
    *** comment: Rad50 KD also causes loss of Nbs1 or Mre11 prot-exp
    *** source: 16087684-Fig-4a
  *** Cdkn1a[Ab] prot-exp[WB] is decreased irt UV (times)
    *** cells: HEK293T in BMS
    *** times: 0++ 30++ 90+ min
    *** partially reqs: Rad50 [RNAi]
    *** comment: Rad50 KD also causes partial loss of Nbs1 and total loss Mre11 prot-exp
    *** source: 16087684-Fig-4a


  *** Cdkn1a[Ab] prot-exp[WB] is decreased irt UV (times)
    *** cells: DK0063 in BMS
    *** times: 0++ 30+ 90 min
    *** source: 16087684-Fig-4b
  *** Cdkn1a[Ab] prot-exp[WB] is decreased irt UV (90 min)
    *** cells: hFibros in BMS
    *** source: 16087684-Fig-4b
