=======================
Phosphorylation on S727
=======================

EgfR--

  *** Stat3[phosAb] phos(S727)[phosAb] is increased irt UV (30 min)
    *** cells: mEFs in BMLS
    *** partially reqs: EgfR [KO]
    *** source: 11553624-Fig-2a

Erk2--

  *** Stat3[phosAb] phos(S727)[phosAb] is increased irt UV (30 min)
    *** cells: JB6CL41 in BMLS
    *** partially inhibited by: xErk2(mnr)"DN" [addition]
    *** source: 11553624-Fig-4a

Jnk1-- and/or Jnk2--

  *** Stat3[phosAb] phos(S727)[phosAb] is increased irt UV (30 min)
    *** cells: JB6CL41 in BMLS
    *** partially inhibited by: xJnk1(mnr)"DN" [addition]
    *** source: 11553624-Fig-4c
  *** Stat3[phosAb] phos(S727)[phosAb] is increased irt UV (30 min)
    *** cells: JB6CL41 in BMLS
    *** partially reqs: Jnk1 [KO]
    *** partially reqs: Jnk2 [KO]
    *** source: 11553624-Fig-4d

Msk1--

  *** Stat3[phosAb] phos(S727)[phosAb] is increased irt UV (30 min)
    *** cells: JB6CL41<xMsk1> in BMLS
    *** partially inhibited by: Msk1(mnr)"CT-KD" [substitution]
    *** partially inhibited by: Msk1(mnr)"NT-KD" [substitution]
    *** source: 11553624-Fig-6b

P38a--

  *** Stat3[phosAb] phos(S727)[phosAb] is increased irt UV (30 min)
    *** cells: JB6CL41 in BMLS
    *** partially inhibited by: xP38a(mnr)"DN" [addition]
    *** source: 11553624-Fig-4b

chemicals

  *** xStat3[phosAb] phos(S727)[phosAb] is increased irt UV (30 min)
    *** cells: COS1<xStat3> in BMS
    *** unaffected by: SB203580 [pretreatment]
    *** unaffected by: PD98059 [pretreatment]
    *** source: 10521505-Fig-4
  *** Stat3[phosAb] phos(S727)[phosAb] is increased irt UV (30 min)
    *** cells: JB6CL41 in BMLS
    *** inhibited by: AG1478 [pretreatment]
    *** inhibited by: PD153035 [pretreatment]
    *** source: 11553624-Fig-2b
  *** Stat3[phosAb] phos(S727)[phosAb] is increased irt UV (30 min)
    *** cells: JB6CL41 in BMLS
    *** inhibited by: PD98059 [pretreatment]
    *** source: 11553624-Fig-3a
  *** Stat3[phosAb] phos(S727)[phosAb] is increased irt UV (30 min)
    *** cells: JB6CL41 in BMLS
    *** inhibited by: SB202190 [pretreatment]
    *** source: 11553624-Fig-3b
  *** Stat3[phosAb] phos(S727)[phosAb] is increased irt UV (30 min)
    *** cells: JB6CL41 in BMLS
    *** partially inhibited by: H89 [pretreatment]
    *** source: 11553624-Fig-6c
  *** Stat3[phosAb] phos(S727)[phosAb] is increased irt UV (30 min)
    *** cells: JB6CL41 in BMLS
    *** unaffected by: LY294002 [pretreatment]
    *** source: 11553624-Fig-3c
  *** Stat3[phosAb] phos(S727)[phosAb] is increased irt UV (30 min)
    *** cells: JB6CL41 in BMLS
    *** unaffected by: Rapamycin [pretreatment]
    *** source: 11553624-Fig-3c

no extras

  *** xStat3[phosAb] phos(S727)[phosAb] is increased irt UV (30 min)
    *** cells: COS1<xStat3> in BMS
    *** source: 10521505-Fig-1a
  *** Stat3[phosAb] phos(S727)[phosAb] is increased irt UV (30 min)
    *** cells: JB6CL41 in BMLS
    *** source: 11553624-Fig-1a
  *** Stat3[phosAb] phos(S727)[phosAb] is increased irt UV (times)
    *** cells: JB6CL41 in BMLS
    *** times: 0 5+ 10+ 15++ 30++ 45++ 60++ min
    *** source: 11553624-Fig-1b
  *** Stat3[phosAb] phos(S727)[phosAb] is increased irt UV (times)
    *** cells: JB6CL41 in BMLS
    *** times: 0+ 15+++ 30+++ 120+ 360++ 720 min
    *** source: 11553624-Fig-1c

=====================================
No increase in phosphorylaton on Y705
=====================================

  *** Stat3[phosAb] phos(Y705)[phosAb] is decreased irt UV (times)
    *** cells: JB6CL41 in BMLS
    *** times: 0+ 5+ 10+ 15+ 30+ 45 60 min
    *** source: 11553624-Fig-1b
  *** xStat3[phosAb] phos(Y705)[phosAb] is unchanged irt UV (30 min)
    *** cells: COS1<xStat3> in BMS
    *** source: 10521505-Fig-1a
  *** Stat3[phosAb] phos(Y705)[phosAb] is unchanged irt UV (30 min)
    *** cells: JB6CL41 in BMLS
    *** source: 11553624-Fig-1a
  *** Stat3[phosAb] phos(Y705)[phosAb] is unchanged irt UV (30 min)
    *** cells: JB6CL41 in BMLS
    *** unaffected by: AG1478 [pretreatment]
    *** unaffected by: PD153035 [pretreatment]
    *** source: 11553624-Fig-2b
  *** Stat3[phosAb] phos(Y705)[phosAb] is unchanged irt UV (30 min)
    *** cells: JB6CL41 in BMLS
    *** unaffected by: Jnk1 [KO]
    *** unaffected by: Jnk2 [KO]
    *** source: 11553624-Fig-4d
  *** Stat3[phosAb] phos(Y705)[phosAb] is unchanged irt UV (30 min)
    *** cells: JB6CL41 in BMLS
    *** unaffected by: xErk2(mnr)"DN" [addition]
    *** source: 11553624-Fig-4a
  *** Stat3[phosAb] phos(Y705)[phosAb] is unchanged irt UV (30 min)
    *** cells: JB6CL41 in BMLS
    *** unaffected by: xJnk1(mnr)"DN" [addition]
    *** source: 11553624-Fig-4c
  *** Stat3[phosAb] phos(Y705)[phosAb] is unchanged irt UV (30 min)
    *** cells: JB6CL41 in BMLS
    *** unaffected by: xP38a(mnr)"DN" [addition]
    *** source: 11553624-Fig-4b
  *** Stat3[phosAb] phos(Y705)[phosAb] is unchanged irt UV (30 min)
    *** cells: mEFs in BMLS
    *** bkg reqs: EgfR [KO]
    *** source: 11553624-Fig-2a


=============================================
Oligo-Binding or increase in nuclear location
=============================================

  *** Stat3[Ab] oligo-binding[EMSA] is increased irt UV (30 min)
    *** cells: JB6CL41 in BMLS "nuclear extracts"
    *** inhibited by: xErk2(mnr)"DN" [addition]
    *** inhibited by: xJnk1(mnr)"DN" [addition]
    *** inhibited by: xP38a(mnr)"DN" [addition]
    *** source: 11553624-Fig-8c
  *** Stat3[Ab] oligo-binding[EMSA] is increased irt UV (30 min)
    *** cells: JB6CL41 in BMLS "nuclear extracts"
    *** source: 11553624-Fig-8a
  *** Stat3[Ab] oligo-binding[EMSA] is increased irt UV (30 min)
    *** cells: JB6CL41 in BMLS "nuclear extracts"
    *** source: 11553624-Fig-8b
  *** Stat3[Ab] oligo-binding[EMSA] is increased irt UV (30 min)
    *** cells: JB6CL41<xMsk1> in BMLS "nuclear extracts"
    *** partially inhibited by: Msk1(mnr)"CT-KD" [substitution]
    *** partially inhibited by: Msk1(mnr)"NT-KD" [substitution]
    *** source: 11553624-Fig-8b
  *** Stat3[Ab] oligo-binding[EMSA] is increased irt UV (30 min)
    *** cells: JB6CL41<xMsk1> in BMLS "nuclear extracts"
    *** source: 11553624-Fig-8a
