UniProt(T444/S447) CST(T421/S424)
UniProt(T252)      CST(S229)
UniProt(S394)      CST(S371)
UniProt(T412)      CST(T389)
UniProt(S434)      CST(S411)

================================================
Semi-Direct Phosphorylation on T412 by Raptor-IP
================================================

  *** rS6k1[32P] phos[32P-ATP] is increased by Raptor[Ab]IP
    *** cells: none
    *** comment: Raptor-IP is from HEK293 in BMS
    *** inhibited by: rFkbp12 + Rapamycin [addition]
    *** source: 15268862-Fig-3e
  *** rS6k1[32P] phos[32P-ATP] is increased by Raptor[Ab]IP
    *** cells: none
    *** comment: Raptor-IP is from HELA in BMS
    *** inhibited by: rFkbp12 + Rapamycin [addition]
    *** source: 15268862-Fig-3e
  *** rS6k1[phosAb] phos(T412)[phosAb] is increased by Raptor[Ab]IP
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** partially inhibited by: rS6k1(mnr)"F5A" [substitution]
    *** unaffected by: rS6k1(mnr)"delCT" [substitution]
    *** partially inhibited by: rS6k1(mnr)"F5AdelCT" [substitution]
    *** source: 15809305-Fig-3b
  *** rS6k1[phosAb] phos(T412)[phosAb] is increased by Raptor[Ab]IP
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** unaffected by: rFkbp12 [addition]
    *** inhibited by: rFkbp12 + Rapamycin [addition]
    *** source: 15809305-Fig-3c
  *** rS6k1(355-438)[phosAb] phos(T412)[phosAb] is increased by Raptor[Ab]IP
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** unaffected by: rS6k1(355-525) [substitution]
    *** source: 15809305-Fig-3d
  *** rS6k1[phosAb] phos(T412)[phosAb] is increased by Raptor[Ab]IP
    *** cells: none
    *** IPfrom: HEK293 in BMS
    *** source: 18925875-Fig-4e

============================================================
Semi-Direct Phosphorylation on T412 is not caused by Mtorc2
============================================================

  *** rS6k1[phosAb] phos(T412)[phosAb] is increased by Mtor[Ab]IP
    *** cells: none
    *** IPfrom: mEFs in BMS
    *** does not req: Rictor [KO]
    *** source: 18925875-Fig-4b
  *** rS6k1[phosAb] phos(T412)[phosAb] is unchanged by Rictor[Ab]IP
    *** cells: none
    *** IPfrom: HEK293 in BMS
    *** source: 18925875-Fig-4e
  *** rS6k1[32P] phos[32P-ATP] is unchanged by Rictor[Ab]IP
    *** cells: none
    *** comment: Rictor-IP is from HEK293 in BMS
    *** comment: unaffected by addition of (rFkbp12 + Rapamycin) to kinase reaction
    *** source: 15268862-Fig-3e
  *** rS6k1[32P] phos[32P-ATP] is unchanged by Rictor[Ab]IP
    *** cells: none
    *** comment: Rictor-IP is from HELA in BMS
    *** comment: unaffected by addition of (rFkbp12 + Rapamycin) to kinase reaction
    *** source: 15268862-Fig-3e
  *** rS6k1[phosAb] phos(T412)[phosAb] is unchanged by Rictor[Ab]IP
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** unaffected by: rS6k1(mnr)"F5A" [substitution]
    *** comment: deletion of rS6k1 C-terminus causes an increase in T412 phos by Rictor[Ab]IP
    *** source: 15809305-Fig-3b

=========================================
S6k1 basal phosphorylation requires Mlst8
=========================================

  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HEK293T in BMS
    *** reqs: Mlst8 [RNAi]
    *** source: 12718876(D)
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itpo xMlst8
    *** cells: HEK293T in BMS
    *** source: 12718876(D)
  ------- contradiction ----------------------------------------------
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: mEFs<xSgk1(61-431)> in BMS
    *** does not req: Mlst8 [RNAi]
    *** source: 18925875-Fig-1d
  --------------------------------------------------------------------
  *** S6k1[phosAb] phos(T444/S447)[phosAb] is detectable
    *** cells: HEK293T in BMS
    *** reqs: Mlst8 [RNAi]
    *** source: 12718876(D)
  *** S6k1[phosAb] phos(T444/S447)[phosAb] is increased itpo xMlst8
    *** cells: HEK293T in BMS
    *** source: 12718876(D)

============================================
S6k1 basal phosphorylation does not req Sin1
============================================

  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HEK293T in BMS
    *** does not req: Sin1 [RNAi]
    *** source: 16919458-Fig-3a
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HELA in BMS
    *** does not req: Sin1 [RNAi]
    *** source: 16919458-Fig-3a
  --------------------------------------------------------------------
  *** S6k1[phosAb] phos(T444/S447)[phosAb] is detectable
    *** cells: HEK293 in BMS
    *** does not req: Sin1 [RNAi]
    *** source: 17043309-Fig-2b
  *** S6k1[phosAb] phos(T444/S447)[phosAb] is detectable
    *** cells: HELA in BMS
    *** does not req: Sin1 [RNAi]
    *** source: 17043309-Fig-2a
  --------------------------------------------------------------------

========================================
S6k1 basal phosphorylation requires Mtor
========================================

  *** rS6k1a2(332-415)[32P] phos[32P-ATP] is increased by xMtor[tAb]IP
    *** cells: none
    *** IPfrom: HEK293<xMtor> in BMS
    *** partially inhibited by: rS6k1a2(332-415/T412A) [substitution]
    *** unaffected by: rS6k1a2(332-415/T404A) [substitution]
    *** source: 9465032-Fig-3b
  *** rS6k1a2(332-502)[32P] phos[32P-ATP] is increased by xMtor[tAb]IP
    *** cells: none
    *** IPfrom: HEK293<xMtor> in BMS
    *** inhibited by: xMtor(D2357E)"KD" [substitution]
    *** source: 9465032-Fig-1a
  *** rS6k1a2(332-502)[32P] phos[32P-ATP] is increased by xMtor[tAb]IP
    *** cells: none
    *** IPfrom: HEK293<xMtor> in BMS
    *** partially inhibited by: rFkbp12 + Rapamycin [addition]
    *** source: 9465032-Fig-1b
  *** rS6k1a2[32P] phos[32P-ATP] is increased by xMtor[tAb]IP
    *** cells: none
    *** IPfrom: HEK293<xMtor> in BMS
    *** partially inhibited by: rFkbp12 + Rapamycin [addition]
    *** source: 9465032-Fig-1b
  *** rS6k1a2[32P] phos[32P-ATP] is increased by xMtor[tAb]IP
    *** cells: none
    *** IPfrom: HEK293<xMtor> in BMS
    *** unaffected by: rS6k1a2(332-502) [substitution]
    *** unaffected by: rS6k1a2(332-415) [substitution]
    *** inhibited by: rS6k1a2(415-502) [substitution]
    *** inhibited by: rS6k1a2(66-235) [substitution]
    *** source: 9465032-Fig-1a
  *** xS6k1a2[GST]IP phos[32P-ATP] is increased by xMtor[tAb]IP
    *** cells: none
    *** IP1from: HEK293<xS6k1a2> in BMS
    *** IP2from: HEK293<xMtor> in BMS
    *** inhibited by: xMtor(D2357E)"KD" [substitution]
    *** comment: xS6k1a2[GST]IP with GST is added to the CTerm is used
    *** comment: xS6k1a2[GST]IP is CA if GST is added to the CTerm
    *** source: 9465032-Fig-3d
  *** rS6k1(332-415)[32P] phos[32P-ATP] is increased by xMtor[tAb]IP
    *** cells: none
    *** IPfrom: HEK293 in BMS
    *** comment: increase is over xMtor(D2357E)"KD"[tAb]IP
    *** partially inhibited by: rS6k1((332-415)/T412A) [substitution]
    *** unaffected by: rS6k1((332-415)/S404A) [substitution]
    *** source: 9405468-Fig-3b
  *** rS6k1[phosAb] phos(T412)[phosAb] is increased by Mtor[Ab]IP
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** partially inhibited by: rS6k1(mnr)"F5A" [substitution]
    *** unaffected by: rS6k1(mnr)"delCT" [substitution]
    *** unaffected by: rS6k1(mnr)"F5AdelCT" [substitution]
    *** source: 15809305-Fig-3b
  *** rS6k1[32P] phos[32P-ATP] is increased by xMtor[tAb]IP
    *** cells: none
    *** IPfrom: HEK293 in BMS
    *** comment: increase is over xMtor(D2357E)"KD"[tAb]IP
    *** source: 9405468-Fig-1a
  *** rS6k1[32P] phos[32P-ATP] is increased by Mtor[Ab]IP
    *** cells: none
    *** IPfrom: HEK293 in BMS
    *** inhibited by: rFkbp12 + Rapamycin [addition]
    *** source: 15268862-Fig-3e
  *** rS6k1(355-438)[phosAb] phos(T412)[phosAb] is increased by Mtor[Ab]IP
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** unaffected by: rS6k1(355-525) [substitution]
    *** source: 15809305-Fig-3d
  -------- phos(S394) ------------------------------------------------
  *** xS6k1[tAb]IP phos(S394)[phosAb] is increased by xMtor[tAb]IP
    *** cells: HEK293 in BMLS
    *** inhibited by: xMtor(D2537E)"KD" [substitution]
    *** source: 11914378-Fig-5a
  --------------------------------------------------------------------
  -------- phos(T412) ------------------------------------------------
  *** xS6k1(23-525)[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HEK293T<xS6k1(23-525)> in BMS
    *** reqs: Mtor [RNAi]
    *** source: 15809305-Fig-2a
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HEK293T in BMS
    *** reqs: Mtor [RNAi]
    *** source: 12718876(D)
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: DROSOPHILAS2 in BMS
    *** reqs: Mtor [RNAi]
    *** source: 15268862-Fig-3d
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HELA in BMS
    *** reqs: Mtor [RNAi]
    *** source: 15268862-Fig-4a
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: A549 in BMS
    *** reqs: Mtor [RNAi]
    *** source: 15718470-Fig-2a
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HEK293T in BMS
    *** reqs: Mtor [RNAi]
    *** source: 15718470-Fig-2b
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HELA in BMS
    *** reqs: Mtor [RNAi]
    *** source: 15718470-Fig-2b
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HT29 in BMS
    *** reqs: Mtor [RNAi]
    *** source: 15718470-Fig-2a
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: PC3 in BMS
    *** reqs: Mtor [RNAi]
    *** source: 15718470-Fig-2b
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: MCF7 in BMS
    *** reqs: Mtor [RNAi]
    *** source: 18339839-Fig-2c
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: MDAMB231 in BMS
    *** reqs: Mtor [RNAi]
    *** source: 18339839-Fig-2c
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: PC3 in BMS
    *** reqs: Mtor [RNAi]
    *** source: 18339839-Fig-2c
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: 786O in BMS
    *** partially reqs: Mtor [RNAi]
    *** source: 19114562-Fig-1
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HEK293T in BMS
    *** reqs: Mtor [RNAi]
    *** source: 16603397-Fig-3c
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HELA in BMS
    *** reqs: Mtor [RNAi]
    *** source: 16603397-Fig-3c
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: H460 in BMS
    *** reqs: Mtor [RNAi]
    *** source: 16603397-Fig-3c
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HEK293T in BMS
    *** reqs: Mtor [RNAi]
    *** source: 15809305-Fig-1b
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itpo xMtor
    *** cells: WM35 in BMS
    *** source: 18570873-Fig-1
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itpo xMtor
    *** cells: WM35 in BMS
    *** source: 18570873-Fig-3b
  -------- phos(S434) ------------------------------------------------
  *** S6k1[phosAb] phos(S434)[phosAb] is detectable
    *** cells: HEK293T in BMS
    *** reqs: Mtor [RNAi]
    *** source: 15809305-Fig-1b
  -------- phos(T444/S447) ------------------------------------------------
  *** S6k1[phosAb] phos(T444/S447)[phosAb] is detectable
    *** cells: HEK293T in BMS
    *** reqs: Mtor [RNAi]
    *** source: 12718876(D)
  *** S6k1[phosAb] phos(T444/S447)[phosAb] is detectable
    *** cells: HELA in BMS
    *** reqs: Mtor [RNAi]
    *** source: 17043309-Fig-2a
  *** S6k1[phosAb] phos(T444/S447)[phosAb] is detectable
    *** cells: HEK293 in BMS
    *** reqs: Mtor [RNAi]
    *** source: 17043309-Fig-2b


==========================================
S6k1 basal phosphorylation requires Raptor
===========================================

  ---------------- phos(T412) ----------------------------------------
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: DROSOPHILAS2 in BMS
    *** reqs: Raptor [RNAi]
    *** source: 15268862-Fig-3d
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HELA in BMS
    *** reqs: Raptor [RNAi]
    *** source: 15268862-Fig-4a
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: A549 in BMS
    *** reqs: Raptor [RNAi]
    *** source: 15718470-Fig-2a
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HEK293T in BMS
    *** reqs: Raptor [RNAi]
    *** source: 15718470-Fig-2b
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HELA in BMS
    *** reqs: Raptor [RNAi]
    *** source: 15718470-Fig-2b
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HT29 in BMS
    *** reqs: Raptor [RNAi]
    *** source: 15718470-Fig-2a
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: PC3 in BMS
    *** reqs: Raptor [RNAi]
    *** source: 15718470-Fig-2b
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: 786O in BMS
    *** partially reqs: Raptor [RNAi]
    *** source: 19114562-Fig-1
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HEK293T in BMS
    *** reqs: Raptor [RNAi]
    *** source: 15809305-Fig-1b
  *** xS6k1(23-525)[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HEK293T<xS6k1(23-525)> in BMS
    *** reqs: Raptor [RNAi]
    *** source: 15809305-Fig-2a
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: WM35<xMtor> in BMS
    *** reqs: Raptor [RNAi]
    *** source: 18570873-Fig-7a
  ---------------- phos(S434) -----------------------------------------
  *** S6k1[phosAb] phos(S434)[phosAb] is detectable
    *** cells: HEK293T in BMS
    *** reqs: Raptor [RNAi]
    *** source: 15809305-Fig-1b
  --------------------------------------------------------------------
  *** S6k1[phosAb] phos(T444/S447)[phosAb] is detectable
    *** cells: HELA in BMS
    *** partially reqs: Raptor [RNAi]
    *** source: 17043309-Fig-2a
  *** S6k1[phosAb] phos(T444/S447)[phosAb] is detectable
    *** cells: HELA in BMS
    *** partially reqs: Raptor [RNAi]
    *** source: 17043309-Fig-2b
  ---------------- ?????????? ----------------------------------------
  *** S6k1[phosAb] phos(T412)[phosAb] is decreased itpo xRaptor
    *** cells: HEK293T in BMS
    *** inhibited by: xRaptor(Y194A/D195A/C196A) [substitution]
    *** source: 12150925-Fig-6e

  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: WM35<xMtor> in BMS
    *** reqs: Raptor [RNAi]
    *** comment: subject was published as Sgk1 phos(S422) but was shown by 18925875 to be S6k1(T412)
    *** source: 18570873-Fig-7a

==================================================
S6k1 basal phosphorylation does not require Rictor
==================================================

  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Rictor [RNAi]
    *** cells: HEK293T in BMS
    *** source: 15268862-Fig-3c
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Rictor [RNAi]
    *** cells: DROSOPHILAS2 in BMS
    *** source: 15268862-Fig-3d
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HELA in BMS
    *** does not req: Rictor [RNAi]
    *** source: 15268862-Fig-4a
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Rictor [RNAi]
    *** cells: HELA in BMS
    *** source: 15268862-Fig-3c
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: A549 in BMS
    *** does not req: Rictor [RNAi]
    *** source: 15718470-Fig-2a
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HEK293T in BMS
    *** does not req: Rictor [RNAi]
    *** source: 15718470-Fig-2b
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HELA in BMS
    *** does not req: Rictor [RNAi]
    *** source: 15718470-Fig-2b
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HT29 in BMS
    *** does not req: Rictor [RNAi]
    *** source: 15718470-Fig-2a
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: PC3 in BMS
    *** does not req: Rictor [RNAi]
    *** source: 15718470-Fig-2b
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Rictor [RNAi]
    *** cells: HELA in BMS
    *** source: 16919458-Fig-3a
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HEK293T in BMS
    *** does not req: Rictor [RNAi]
    *** source: 16919458-Fig-3a
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: 786O in BMS
    *** does not req: Rictor [RNAi]
    *** source: 19114562-Fig-1
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HEK293T in BMS
    *** does not req: Rictor [RNAi]
    *** source: 15809305-Fig-1b
  *** xS6k1(23-525)[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HEK293T<xS6k1(23-525)> in BMS
    *** does not req: Rictor [RNAi]
    *** source: 15809305-Fig-2a
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: WM35<xMtor> in BMS
    *** does not req: Rictor [RNAi]
    *** source: 18570873-Fig-7a
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: mEFs<xSgk1(61-431)> in BMS
    *** does not req: Rictor [RNAi]
    *** source: 18925875-Fig-1a
  -------- phos(S434) ------------------------------------------------
  *** S6k1[phosAb] phos(S434)[phosAb] is detectable
    *** cells: HEK293T in BMS
    *** does not req: Rictor [RNAi]
    *** source: 15809305-Fig-1b
  -------- phos(T444/S447) ------------------------------------------------
  *** S6k1[phosAb] phos(T444/S447)[phosAb] is detectable
    *** cells: HELA in BMS
    *** does not req: Rictor [RNAi]
    *** source: 17043309-Fig-2a
  *** S6k1[phosAb] phos(T444/S447)[phosAb] is detectable
    *** cells: HEK293 in BMS
    *** does not req: Rictor [RNAi]
    *** source: 17043309-Fig-2b
  --------------------------------------------------------------------

*** S6k1 can be phosed on T412 by Rictor complex if C-terminus is removed

  *** rS6k1(355-438)[phosAb] phos(T412)[phosAb] is increased by Rictor[Ab]IP
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** inhibited by: rS6k1(355-525) [substitution]
    *** source: 15809305-Fig-3d
  *** rS6k1(mnr)"F5AdelCT"[phosAb] phos(T412)[phosAb] is increased by Rictor[Ab]IP
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** unaffected by: rFkbp12 [addition]
    *** unaffected by: rFkbp12 + Rapamycin [addition]
    *** source: 15809305-Fig-3c

  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: mEFs<xSgk1> in BMS
    *** does not req: Rictor [RNAi]
    *** source: 18925875-Fig-1c

  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: WM35<xMtor> in BMS
    *** does not req: Rictor [RNAi]
    *** comment: subject was published as Sgk1 phos(S422) but was shown by 18925875 to be S6k1(T412)
    *** source: 18570873-Fig-7a


================================================
S6k1 basal phosphorylation does not require Sin1
================================================

  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: mEFs<xSgk1(61-431)> in BMS
    *** does not req: Sin1 [RNAi]
    *** source: 18925875-Fig-1e

================================================
S6k1 basal phosphorylation does not require Sgk1
================================================

  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: WM35<xSgk1> in BMS
    *** inhibited by: xSgk1(S422A) [substitution]
    *** unaffected by: xSgk1(T256A) [substitution]
    *** unaffected by: xSgk1(F385A) [substitution]
    *** comment: subject was published as Sgk1 phos(S422) but was shown by 18925875 to be S6k1(T412)
    *** source: 18570873-Fig-5a

===============================================
S6k1 basal phosphorylation is inhibited by Tsc2
===============================================

  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Tsc2 [RNAi]
    *** cells: WM35 in BMS
    *** comment: subject was published as Sgk1 phos(S422) but was shown by 18925875 to be S6k1(T412)
    *** source: 18570873-Fig-7e

====================================================
S6k1 basal phosphorylation is inhibited by Rapamycin
====================================================

  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HEK293<xSgk1> in BMS
    *** inhibited by: PI103 [pretreatment]
    *** inhibited by: Rapamycin [pretreatment]
    *** source: 18925875-Fig-5a
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HELA<xSgk1> in BMS
    *** inhibited by: PI103 [pretreatment]
    *** inhibited by: Rapamycin [pretreatment]
    *** source: 18925875-Fig-5c
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: MCF7<xSgk1> in BMS
    *** inhibited by: PI103 [pretreatment]
    *** inhibited by: Rapamycin [pretreatment]
    *** source: 18925875-Fig-5b
  *** S6k1[phosAb] phos(T412)[phosAb] is decreased irt Rapamycin (times)
    *** cells: WM35 in BMS
    *** times: 0+ 15 30 60 min
    *** comment: this reqs much higher Rapa conc in WM35<xMtor> cells
    *** comment: subject was published as Sgk1 phos(S422) but was shown by 18925875 to be S6k1(T412)
    *** source: 18570873-Fig-3b























