===========================
Phosphorylation on Tyrosine
===========================

  *** Pik3r1[Ab]IP Yphos[pYAb] is decreased irt IL4 (1 min)
    *** cells: RAMOS in BMLS
    *** source: 9065461-Fig-2b

Contradiction

  *** Pik3rs[Ab]IP Yphos[pYAb] is unchanged irt IL4 (times)
    *** cells: hPBTCs in BMLS
    *** times: 0 1 5 min
    *** source: 9973481-Fig-2a

=====================
Lipid Kinase Activity
=====================

  *** Pik3rs[Ab]IP IVLKA(PtdIns)[TLC] is increased irt IL4 (30 min)
    *** cells: TS1<xIL2Ra><xIL2Rb> in BMS "IL2-deprived"
    *** unaffected by: ToxinB [pretreatment]
    *** source: 9029085-Fig-5

============================================
Coppt with other members of the IL4R complex
============================================

Irs2--

  *** Pik3rs[Ab] copptby[WB] Irs2[Ab] is increased irt IL4 (15 min)
    *** cells: M1241 in BMS
    *** inhibited by: xFes(K590E)"KD" [addition]
    *** source: 11160325-Fig-4a
  *** Pik3rs[Ab] copptby[WB] Irs2[Ab] is increased irt IL4 (15 min)
    *** cells: M1241<xFes> in BMS
    *** inhibited by: xFes(K590E)"KD" [substitution]
    *** source: 11160325-Fig-4a
  *** Pik3rs[Ab] copptby[WB] Irs2[Ab] is increased irt IL4 (times)
    *** cells: hPBMCs in BMLS
    *** times: 0 5+ 15+ min
    *** source: 7499365-Fig-3

==================
Relocation to IL4R
==================

  *** xIL4R[Ab]IP IVLKA(PtdIns)[TLC] is increased irt IL4 (tnr)
    *** cells: COS7 in BMLS
    *** source: 8916957-Fig-5a

