=============
Transcription
=============

Irf1--

  *** IL12b-gene mRNA[RTPCR] is increased irt Lps (6 hr)
    *** cells: mPECs in BMS
    *** partially reqs: Irf1 [KO]
    *** source: 10415056(D)

Irf2--

  *** IL12b-gene mRNA[RTPCR] is increased irt Lps (6 hr)
    *** cells: mPECs in BMS
    *** partially reqs: Irf2 [KO]
    *** source: 10415056(D)

Irf5--

  *** IL12b-gene mRNA[RTPCR] is increased irt Lps (times)
    *** cells: mSMacs in BMS
    *** times: 0 2++ 4+ 6+ 12+ hr
    *** reqs: Irf5 [KO]
    *** source: 15665823-Fig-2d

Myd88--

  *** IL12b-gene mRNA[RTPCR] is increased irt Lps (2 hr)
    *** cells: mBMMs in BMS
    *** reqs: Myd88 [KO]
    *** source: 19898473-Fig-6b

Nfkbiz--

  *** IL12b-gene mRNA[MicroArray] is increased irt Lps (4 hr)
    *** cells: mPECs in BMS
    *** reqs: Nfkbiz [KO]
    *** source: 15241416-Fig-S4a
  *** IL12b-gene mRNA[Northern] is increased irt Lps (times)
    *** cells: mPECs in BMS
    *** times: 0 2++ 4++ 6+ hr
    *** reqs: Nfkbiz [KO]
    *** source: 15241416-Fig-3e

not Pias4--  inhibitory

  *** IL12b-gene mRNA[RTPCR] is increased irt Lps (times)
    *** cells: mBMDCs in BMS
    *** times: 0 60+ 180++ 360++ min
    *** repressed by: Pias4 [KO]
    *** source: 17606919-Fig-5b

not Traf3--  inhibitory

  *** IL12b-gene mRNA[RTPCR] is increased irt Lps (90 min)
    *** cells: mBMMs in BMS
    *** repressed by: Traf3 [KO]
    *** source: 16306937-Fig-S3c

not Traf6--

  *** IL12b-gene mRNA[RTPCR] is increased irt Lps (6 hr)
    *** cells: mBMMs in BMS
    *** does not req: Traf6 [KO]
    *** source: 16306937-Fig-S5c

Trif--

  *** IL12b-gene mRNA[RTPCR] is increased irt Lps (2 hr)
    *** cells: mBMMs in BMS
    *** partially reqs: Trif [fmut]
    *** source: 19898473-Fig-6b

Chemicals

  *** IL12b-gene mRNA[Northern] is increased irt Lps (6 hr)
    *** cells: mPECs in BMLS
    *** partially inhibited by: Dexamethasone [addition]
    *** partially inhibited by: GW7845 [addition]
    *** partially inhibited by: T1317 [addition]
    *** partially inhibited by: ATRA [addition]
    *** partially inhibited by: Calcitrol [addition]
    *** unaffected by: Estradiol [addition]
    *** source: 16143103-Fig-1d
  *** IL12b-gene mRNA[Northern] is increased irt Lps (6 hr)
    *** cells: mPECs in BMLS
    *** partially inhibited by: Dexamethasone [addition]
    *** partially inhibited by: GW7845 [addition]
    *** inhibited by: Dexamethasone + GW7845 [addition]
    *** source: 16143103-Fig-6b
  *** IL12b-gene mRNA[RTPCR] is increased irt Lps (2 hr)
    *** cells: mBMMs in BMS
    *** inhibited by: SmacMimetic [pretreatment]
    *** source: 19898473-Fig-6a
  *** IL12b-gene mRNA[RTPCR] is increased irt Lps (2 hr)
    *** cells: mBMMs in BMS
    *** inhibited by: SmacMimetic [pretreatment]
    *** source: 19898473-Fig-6b

No extras

  *** IL12b-gene mRNA[Northern] is increased irt Lps (4 hr)
    *** cells: mPECs in BMS
    *** source: 12096038-Fig-1a
  *** IL12b-gene mRNA[Northern] is increased irt Lps (times)
    *** cells: mPECs in BMS
    *** times: 0 7 15 30 60+ 120++ 240++ 360++ min
    *** source: 15241416-Fig-S4b
  *** IL12b-gene mRNA[RPA] is increased irt Lps (5 hr)
    *** cells: hMDDCs in BMS
    *** source: 16895974(D)
  *** IL12b-gene mRNA[RTPCR] is increased irt Lps (3 hr)
    *** cells: mPECs in BMS
    *** source: 16709849(D)
  *** IL12b-gene mRNA[RTPCR] is increased irt Lps (24 hr)
    *** cells: mPECs in BMS
    *** source: 16709849(D)
  *** IL12b-gene mRNA[RTPCR] is increased irt Lps (times)
    *** cells: mPECs in BMS
    *** times: 0 2+ 4++ 6++ 8++ 10+ hr
    *** source: 11179315(D)


=========
Secretion
=========

not Ikk1--

  *** IL12b[Ab] secretion[ELISA] is increased irt Lps (24 hr)
    *** cells: mBMfDCs in BMS
    *** does not req: Ikk1 [KO]
    *** source: 16612387-Fig-1a

inhibited by Irak3--

  *** IL12b[Ab] secretion[ELISA] is increased irt Lps (24 hr)
    *** cells: mBMMs in BMS
    *** repressed by: Irak3 [KO]
    *** source: 12150927-Fig-1a

not Irf4--

  *** IL12b[Ab] secretion[ELISA] is increased irt Lps (24 hr)
    *** cells: mBMMs in BMS
    *** does not req: Irf4 [KO]
    *** source: 16236719-Fig-5

not Irf5--

  *** IL12b[Ab] secretion[ELISA] is increased irt Lps (24 hr)
    *** cells: mBMMs in BMS
    *** does not req: Irf5 [KO]
    *** source: 16236719-Fig-5

not Nlrp3--

  *** IL12b[Ab] secretion[ELISA] is increased irt Lps (16 hr)
    *** cells: mBMMs in BMS
    *** does not req: Nlrp3 [KO]
    *** source: 16407890(D)

not Nod2--

  *** IL12b[Ab] secretion[ELISA] is increased irt Lps (16 hr)
    *** cells: mBMMs in BMS
    *** does not req: Nod2 [KO]
    *** source: 16407890(D)

inhibited by Socs1--

  *** IL12b[Ab] secretion[ELISA] is increased irt Lps (12 hr)
    *** cells: mSACs in BMS
    *** repressed by: Socs1 [KO]
    *** source: 12433373-Fig-2b

not Socs3--

  *** IL12b[Ab] secretion[ELISA] is increased irt Lps (5 hr)
    *** cells: mBMMs in BMS
    *** does not req: Socs3 [KO]
    *** source: 12754506-Fig-1b

not TLR7--

  *** IL12b[Ab] secretion[ELISA] is increased irt Lps (24 hr)
    *** cells: mPECs in BMS
    *** does not req: TLR7 [KO]
    *** source: 11812998-Fig-3a

not TLR9--

  *** IL12b[Ab] secretion[ELISA] is increased irt Lps (24 hr)
    *** cells: mBMDCs in BMS
    *** does not req: TLR9 [KO]
    *** source: 11130078-Fig-3c

Ifng-- cotreatment

  *** IL12b[Ab] secretion[ELISA] is increased irt Lps (24 hr)
    *** cells: mBMDCs in BMS
    *** enhanced by: Ifng [cotreatment]
    *** source: 11130078-Fig-3c
  *** IL12b[Ab] secretion[ELISA] is increased irt Lps (24 hr)
    *** cells: mPECs in BMS
    *** enhanced by: Ifng [cotreatment]
    *** source: 11812998-Fig-3a

IL6-- cotreatment

  *** IL12b[Ab] secretion[ELISA] is increased irt Lps (9 hr)
    *** cells: mPECs in BMS
    *** unaffected by: IL6 [cotreatment]
    *** comment: inhibited by IL6 in Socs3-null cells
    *** source: 12754507-Fig-2b

IL10-- cotreatment

  *** IL12b[Ab] secretion[ELISA] is increased irt Lps (5 hr)
    *** cells: mBMMs in BMS
    *** partially inhibited by: IL10 [cotreatment]
    *** source: 12754506-Fig-1b
  *** IL12b[Ab] secretion[ELISA] is increased irt Lps (9 hr)
    *** cells: mPECs in BMS
    *** inhibited by: IL10 [cotreatment]
    *** source: 12754507-Fig-2b

No extras

  *** IL12b[Ab] secretion[ELISA] is increased irt Lps (18 hr)
    *** cells: mPECs in BMS
    *** source: 16996713(D)
  *** IL12b[Ab] secretion[ELISA] is increased irt Lps (times)
    *** cells: mPECs in BMS
    *** times: 0 6+ 24++ hr
    *** source: 11179315(D)

