Myd88 requires Traf6 to return to cyto

  *** Myd88[Ab] copptby[WB] TLR4[Ab] is increased irt Lps (times)
    *** cells: RAW2647 in BMS "membrane fraction"
    *** times: 0 10+ 30 min
    *** comment: decrease at 30 min reqs Traf6 [RNAi]
    *** comment: decrease at 30 min does not req Traf3 [RNAi]
    *** source: 19898473-Fig-2c

Indication that Ciap1 or Ciap2 is required for return to cyto

  *** Myd88[Ab] copptby[WB] TLR4[Ab] is increased irt Lps (times)
    *** cells: mBMMs in BMS "membrane fraction"
    *** times: 0 10+ 30 min
    *** comment: pretreatment with SmacMimetic prevented decrease at 30 min
    *** source: 19898473-Fig-2a

Myd88 returns to cyto with Ciap2

  *** Myd88[Ab] copptby[WB] Ciap2[Ab] is increased irt Lps (times)
    *** cells: mBMMs in BMS "cytosolic fraction"
    *** times: 0 10+ 30+ min
    *** source: 19898473-Fig-S4a
  *** Myd88[Ab] copptby[WB] Ciap2[Ab] is increased irt Lps (times)
    *** cells: mBMMs in BMS "membrane fraction"
    *** times: 0 10+ 30 min
    *** source: 19898473-Fig-S4a

Myd88 returns to cyto with Tak1

  *** Myd88[Ab] copptby[WB] Tak1[Ab] is increased irt Lps (times)
    *** cells: mBMMs in BMS "cytosolic fraction"
    *** times: 0 10+ 30+ min
    *** inhibited by: SmacMimetic [pretreatment]
    *** source: 19898473-Fig-2a
