*** Cbl--
  *** Cbl[Ab] snaggedby[WB] rYwhaq[GST] is increased irt anti-Cd3 (5 min)
    *** cells: hPBTCs in BMS
    *** source: 11024037-Fig-4a
  *** Cbl[Ab]IP Yphos[pYAb] is increased irt anti-Cd3 (times)
    *** cells: hPBTCs in BMS
    *** times: 0 1+ 2+ 5+ min
    *** source: 11024037-Fig-3a
*** Cdk2--
  *** Cdk2[Ab] prot-exp[WB] is increased irt anti-Cd3 (18 hr)
    *** cells: mSpCs in BMS
    *** source: 10072077-Fig-6a
*** Cdk4--
  *** Cdk4[Ab] prot-exp[WB] is unchanged irt anti-Cd3 (18 hr)
    *** cells: mSpCs in BMS
    *** source: 10072077-Fig-6a
*** Cdk6--
  *** Cdk6[Ab] prot-exp[WB] is increased irt anti-Cd3 (18 hr)
    *** cells: mSpCs in BMS
    *** does not req: Stat5a [KO]
    *** does not req: Stat5b [KO]
    *** source: 10072077-Fig-6b
  *** Cdk6[Ab] prot-exp[WB] is increased irt anti-Cd3 (18 hr)
    *** cells: mSpCs in BMS
    *** reqs: Stat5a and/or Stat5b [DKO]
    *** source: 10072077-Fig-6a
*** Cdkn1b--
  *** Cdkn1b[Ab] prot-exp[WB] is decreased irt anti-Cd3 (18 hr)
    *** cells: mSpCs in BMS
    *** does not req: Stat5a or Stat5b [DKO]
    *** source: 10072077-Fig-6a
*** CyclinAs--
*** CyclinAs--
  *** CyclinAs[Ab] prot-exp[WB] is increased irt anti-Cd3 (18 hr)
    *** cells: mSpCs in BMS
    *** does not req: Stat5a [KO]
    *** does not req: Stat5b [KO]
    *** source: 10072077-Fig-6b
  *** CyclinAs[Ab] prot-exp[WB] is increased irt anti-Cd3 (18 hr)
    *** cells: mSpCs in BMS
    *** reqs: Stat5a and/or Stat5b [DKO]
    *** source: 10072077-Fig-6a
*** CyclinD2--
  *** CyclinD2[Ab] prot-exp[WB] is increased irt anti-Cd3 (18 hr)
    *** cells: mSpCs in BMS
    *** partially reqs: Stat5a [KO]
    *** partially reqs: Stat5b [KO]
    *** source: 10072077-Fig-6b
  *** CyclinD2[Ab] prot-exp[WB] is increased irt anti-Cd3 (18 hr)
    *** cells: mSpCs in BMS
    *** reqs: Stat5a and/or Stat5b [DKO]
    *** source: 10072077-Fig-6a
*** CyclinD3--
  *** CyclinD3[Ab] prot-exp[WB] is increased irt anti-Cd3 (18 hr)
    *** cells: mSpCs in BMS
    *** partially reqs: Stat5a [KO]
    *** partially reqs: Stat5b [KO]
    *** source: 10072077-Fig-6b
  *** CyclinD3[Ab] prot-exp[WB] is increased irt anti-Cd3 (18 hr)
    *** cells: mSpCs in BMS
    *** reqs: Stat5a and/or Stat5b [DKO]
    *** source: 10072077-Fig-6a
  *** CyclinEs[Ab] prot-exp[WB] is increased irt anti-Cd3 (18 hr)
    *** cells: mSpCs in BMS
    *** source: 10072077-Fig-6a
*** Erks--
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt anti-Cd3 (5 min)
    *** cells: JURKATT in BMS
    *** unaffected by: U73343 [addition]
    *** unaffected by: U73122 [addition]
    *** inhibited by: HerbimycinA [addition]
    *** source: 10807788-Fig-2
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt anti-Cd3 (15 min)
    *** cells: JURKAT<Pten~null> in BMS
    *** inhibited by: xCbl [addition]
    *** source: 11024037-Fig-6a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt anti-Cd3 (15 min)
    *** cells: JURKATT in BMS
    *** enhanced by: xRasGrp1 [addition]
    *** source: 10807788-Fig-4c
*** Fos--
  *** Fos[Ab] prot-exp[WB] is increased irt anti-Cd3 (times)
    *** cells: JURKAT<Pten~null><xBraf> in BMS
    *** times: 0 60+ 180+ min
    *** unaffected by: xBraf(T598A/S601A) [substitution]
    *** source: 15339934-Fig-6a
*** Foxp3--
  *** Foxp3-gene mRNA[RTPCR] is increased irt anti-Cd3 (24 hr)
    *** cells: EL4<xFoxp3> in BMS
    *** source: 18434325-Fig-3a
  *** Foxp3-gene mRNA[RTPCR] is unchanged irt anti-Cd3 (6 hr)
    *** cells: hPBMCs<Cd4~pos><IL2Ra~pos> in BMS
    *** source: 16645171-Fig-1a
  *** Foxp3-gene mRNA[RTPCR] is unchanged irt anti-Cd3 (24 hr)
    *** cells: EL4 in BMS
    *** source: 18434325-Fig-3a
*** Hras--
  *** Hras[Ab] GTP-association[BDPD] is increased irt anti-Cd3 (5 min)
    *** cells: JURKATT in BMS
    *** unaffected by: U73343 [addition]
    *** unaffected by: U73122 [addition]
    *** inhibited by: HerbimycinA [addition]
    *** source: 10807788-Fig-2
  *** Hras[Ab] GTP-association[BDPD] is increased irt anti-Cd3 (times)
    *** cells: JURKATT in BMS
    *** times: 0 5++ 30++ 60+ 90+ 120+ min
    *** source: 10807788-Fig-3a
  *** Hras[Ab] GTP-association[BDPD] is increased irt anti-Cd3 (times)
    *** cells: JURKATT in BMS "containing CdCl2"
    *** times: 0 10++ 30++ 60+ 300+ min
    *** enhanced by: xRasGrp1 [addition]
    *** source: 10807788-Fig-4b
  *** Hras[Ab]IP GTP-association[TLC] is increased irt anti-Cd3 (5 min)
    *** cells: hPHAblasts in BMS "IL2-deprived"
    *** unaffected by: IL2 [cotreatment]
    *** source: 1532814-Fig-5
  *** xHras[tAb] GTP-association[BDPD] is increased irt anti-Cd3 (times)
    *** cells: JURKAT<Pten~null> in BMLS
    *** times: 0 2+ 5+ min
    *** source: 15226433(D)
*** Ifng--
  *** Ifng-gene mRNA[Northern] is increased irt anti-Cd3 (4 hr)
    *** cells: 3F6 in BMS
    *** source: 10097133-Fig-1a
  *** Ifng-gene mRNA[RTPCR] is increased irt anti-Cd3 (5 hr)
    *** cells: mSpTh1 in BMS "OVA specific"
    *** source: 17088898-Fig-1a
  *** Ifng-gene mRNA[RTPCR] is increased irt anti-Cd3 (5 hr)
    *** cells: mSpTh1 in BMS "OVA specific"
    *** source: 17581589-Fig-1a
  *** Ifng-gene mRNA[RTPCR] is unchanged irt anti-Cd3 (5 hr)
    *** cells: mSpTh0 in BMS "OVA specific"
    *** source: 17581589-Fig-1a
  *** Ifng-gene mRNA[RTPCR] is unchanged irt anti-Cd3 (5 hr)
    *** cells: mSpTh2 in BMS "OVA specific"
    *** source: 17088898-Fig-1a
  *** Ifng-gene mRNA[RTPCR] is unchanged irt anti-Cd3 (5 hr)
    *** cells: mSpTh2 in BMS "OVA specific"
    *** source: 17581589-Fig-1a
  *** Ifng-gene mRNA[RTPCR] is unchanged irt anti-Cd3 (5 hr)
    *** cells: mSpTh17 in BMS "OVA specific"
    *** source: 17088898-Fig-1a
  *** Ifng-gene mRNA[RTPCR] is unchanged irt anti-Cd3 (5 hr)
    *** cells: mSpTh17 in BMS "OVA specific"
    *** source: 17581589-Fig-1a
  *** Ifng[Ab] secretion[ELISA] is increased irt anti-Cd3 (3 days)
    *** cells: hPBMCs in BMS
    *** inhibited by: IL10 [cotreatment]
    *** source: 10637267-Fig-3a
  *** Ifng[Ab] secretion[ELISA] is increased irt anti-Cd3 (6 hr)
    *** cells: mSpCD4TCs in BMS "pretreated with anti-Cd3 + anti-Cd28 + IL4 for 5 days"
    *** does not req: Stat6 [KO]
    *** reqs: Tbet [KO]
    *** source: 19324016-Fig-2b
  *** Ifng[Ab] secretion[ELISA] is increased irt anti-Cd3 (6 hr)
    *** cells: mSpCD4TCs in BMS "pretreated with anti-Cd3 + anti-Cd28 + IL12 for 5 days"
    *** does not req: Stat6 [KO]
    *** reqs: Tbet [KO]
    *** source: 19324016-Fig-2b
  *** Ifng[Ab] secretion[ELISA] is increased irt anti-Cd3 (8 hr)
    *** cells: mSpTh1 in BMS "OVA-specific"
    *** inhibited by: CsA [pretreatment]
    *** unaffected by: SB203580 [pretreatment]
    *** source: 1175814-Fig-6b
  *** Ifng[Ab] secretion[ELISA] is increased irt anti-Cd3 (8 hr)
    *** cells: mSpTh1 in BMS "OVA-specific"
    *** unaffected by: Tyrphostin1 [pretreatment]
    *** inhibited by: CsA [pretreatment]
    *** unaffected by: SB203580 [pretreatment]
    *** source: 1175814-Fig-6a
  *** Ifng[Ab] secretion[ELISA] is increased irt anti-Cd3 (24 hr)
    *** cells: mLNTCs in BMS
    *** enhanced by: anti-Cd28 [cotreatment]
    *** source: 14734615-Fig-4a
  *** Ifng[Ab] secretion[ELISA] is increased irt anti-Cd3 (24 hr)
    *** cells: mLNTCs in BMS
    *** reqs: Stat4 [KO]
    *** source: 14734615-Fig-4a
  *** Ifng[Ab] secretion[ELISA] is increased irt anti-Cd3 (24 hr)
    *** cells: mSPOvaBlasts<Cd4~pos> in BMS "resting"
    *** unaffected by: xGadd45b [addition]
    *** source: 1175814-Fig-3b
  *** Ifng[Ab] secretion[ELISA] is increased irt anti-Cd3 (24 hr)
    *** cells: mSpTh1 in BMS
    *** partially reqs: Ripk2 [KO]
    *** source: 11894097-Fig-3b
  *** Ifng[Ab] secretion[ELISA] is increased irt anti-Cd3 (24 hr)
    *** cells: mSpTh1 in BMS "OVA specific"
    *** source: 17088898-Fig-1a
  *** Ifng[Ab] secretion[ELISA] is increased irt anti-Cd3 (24 hr)
    *** cells: mSpTh1 in BMS "OVA-specific"
    *** enhanced by: IL18 [cotreatment]
    *** source: 1175814-Fig-5b
  *** Ifng[Ab] secretion[ELISA] is increased irt anti-Cd3 (24 hr)
    *** cells: mSpTh1 in BMS "OVA-specific"
    *** unaffected by: xIkba(37-317)"DN" [addition]
    *** source: 1175814-Fig-5c
  *** Ifng[Ab] secretion[ELISA] is increased irt anti-Cd3 (24 hr)
    *** cells: mSpTh1 in BMS "OVA-specific"
    *** unaffected by: xMekk4(1-329)"DN" [addition]
    *** unaffected by: xMekk4(1-645)"DN" [addition]
    *** source: 1175814-Fig-5b
  *** Ifng[Ab] secretion[ELISA] is increased irt anti-Cd3 (24 hr)
    *** cells: mSpTh1 in BMS "OVA-specific"
    *** unaffected by: xMekk4(1-329)"DN" [addition]
    *** unaffected by: xMekk4(1-645)"DN" [addition]
    *** source: 1175814-Fig-5c
  *** Ifng[Ab] secretion[ELISA] is increased irt anti-Cd3 (48 hr)
    *** cells: mSpTCs in BMS "pretreated with IL2 + anti-Cd3 + IL12 for 72 hr"
    *** comment: requires IL12 pretreatment [omission]
    *** comment: inhibited by IL4 pretreatment [substitution]
    *** source: 9759857-Fig-5a
  *** Ifng[Ab] secretion[ELISA] is increased irt anti-Cd3 (48 hr)
    *** cells: mSpTCs in BMS "pretreated with IL2 + anti-Cd3 + IL12 for 72 hr"
    *** comment: requires IL12 pretreatment [omission]
    *** comment: inhibited by IL4 pretreatment [substitution]
    *** source: 9759857-Fig-5c
  *** Ifng[Ab] secretion[ELISA] is increased irt anti-Cd3 (72 hr)
    *** cells: mSpCs in BMS
    *** reqs: IL2Rg [KO]
    *** source: 10962026-Fig-3c
  *** Ifng[Ab] secretion[ELISA] is increased irt anti-Cd3 (72 hr)
    *** cells: mSpCs<IL2Rg~null><xIL2Rg> in BMS
    *** inhibited by: xIL2Rg(1-290)"M1" [substitution]
    *** inhibited by: xIL2Rg(1-321)"M2" [substitution]
    *** source: 10962026-Fig-3c
  *** Ifng[Ab] secretion[ELISA] is increased irt anti-Cd3 (times)
    *** cells: mSpTCs in BMS "pretreated with anti-Cd3 + IL12 for 72 hr"
    *** times: 0 3+ 6+ 24++ 48+++ 72+++ hr
    *** source: 9759857-Fig-4b
  *** Ifng[Ab] secretion[ELISA] is unchanged irt anti-Cd3 (24 hr)
    *** cells: mSpTh2 in BMS "OVA specific"
    *** source: 17088898-Fig-1a
  *** Ifng[Ab] secretion[ELISA] is unchanged irt anti-Cd3 (24 hr)
    *** cells: mSpTh17 in BMS "OVA specific"
    *** source: 17088898-Fig-1a
  *** Ifng[Ab] secretion[ELISA] is unchanged irt anti-Cd3 (times)
    *** cells: mSpTCs in BMS "pretreated with IL12 for 72 hr"
    *** times: 0 24 72 hr
    *** source: 9759857-Fig-4b
*** IL2--
  *** IL2-gene mRNA[Northern] is increased irt anti-Cd3 (times)
    *** cells: hPBMCs in BMHIS
    *** times: 0 3+ 6++ 12+ 24 36 48 120 hr
    *** source: 1708096-Fig-1a
  *** IL2[Ab] secretion[ELISA] is increased irt anti-Cd3 (72 hr)
    *** cells: mSpCs in BMS
    *** partially reqs: IL2Rg [KO]
    *** source: 10962026-Fig-3c
  *** IL2[Ab] secretion[ELISA] is increased irt anti-Cd3 (72 hr)
    *** cells: mSpCs<IL2Rg~null><xIL2Rg> in BMS
    *** partially inhibited by: xIL2Rg(1-290)"M1" [substitution]
    *** partially inhibited by: xIL2Rg(1-321)"M2" [substitution]
    *** source: 10962026-Fig-3c
  *** IL2[Ab] secretion[ELISA] is unchanged irt anti-Cd3 (24 hr)
    *** cells: mTh1 in BMS
    *** source: 9177292-Fig-1
*** IL2Ra---
  *** IL2Ra-gene mRNA[Northern] is increased irt anti-Cd3 (times)
    *** cells: hPBMCs in BMHIS
    *** times: 0 3 6+ 12++ 24++ 36++ 48++ 120 hr
    *** source: 1708096-Fig-1a
  *** IL2Ra[Ab] surface-exp[FACS] is increased irt anti-Cd3 (17 hr)
    *** cells: mThyCs<Cd4~pos> in BMS
    *** inhibited by: CsA [cotreatment]
    *** source: 12065418-Fig-8a
  *** IL2Ra[Ab] surface-exp[FACS] is increased irt anti-Cd3 (17 hr)
    *** cells: mThyCs<Cd8~pos> in BMS
    *** inhibited by: CsA [cotreatment]
    *** source: 12065418-Fig-8a
  *** IL2Ra[Ab] surface-exp[FACS] is increased irt anti-Cd3 (times)
    *** cells: hPBMCs in BMS
    *** times: 0 12+ 24++ 36+++ hr
    *** source: 11994454-Fig-6c
*** IL2Rb--
  *** IL2Rb-gene mRNA[Northern] is increased irt anti-Cd3 (times)
    *** cells: hPBMCs in BMHIS
    *** times: 0+ 3+ 6+ 12++ 24++ 36++ 48++ 120+ hr
    *** comment: no control for total RNA
    *** source: 1708096-Fig-1a
*** IL4--
  *** IL4-gene mRNA[RTPCR] is increased irt anti-Cd3 (5 hr)
    *** cells: mSpTh2 in BMS "OVA specific"
    *** source: 17088898-Fig-1a
  *** IL4-gene mRNA[RTPCR] is increased irt anti-Cd3 (5 hr)
    *** cells: mSpTh2 in BMS "OVA specific"
    *** source: 17581589-Fig-1a
  *** IL4-gene mRNA[RTPCR] is unchanged irt anti-Cd3 (5 hr)
    *** cells: mSpTh0 in BMS "OVA specific"
    *** source: 17581589-Fig-1a
  *** IL4-gene mRNA[RTPCR] is unchanged irt anti-Cd3 (5 hr)
    *** cells: mSpTh1 in BMS "OVA specific"
    *** source: 17088898-Fig-1a
  *** IL4-gene mRNA[RTPCR] is unchanged irt anti-Cd3 (5 hr)
    *** cells: mSpTh1 in BMS "OVA specific"
    *** source: 17581589-Fig-1a
  *** IL4-gene mRNA[RTPCR] is unchanged irt anti-Cd3 (5 hr)
    *** cells: mSpTh17 in BMS "OVA specific"
    *** source: 17088898-Fig-1a
  *** IL4-gene mRNA[RTPCR] is unchanged irt anti-Cd3 (5 hr)
    *** cells: mSpTh17 in BMS "OVA specific"
    *** source: 17581589-Fig-1a
  *** IL4[Ab] secretion[ELISA] is increased irt anti-Cd3 (6 hr)
    *** cells: mSpCD4TCs in BMS "pretreated with anti-Cd3 + anti-Cd28 + IL4 for 5 days"
    *** reqs: Stat6 [KO]
    *** does not req: Tbet [KO]
    *** source: 19324016-Fig-2b
  *** IL4[Ab] secretion[ELISA] is increased irt anti-Cd3 (6 hr)
    *** cells: mSpCD4TCs in BMS "pretreated with anti-Cd3 + anti-Cd28 + IL12 for 5 days"
    *** reqs: Stat6 [KO]
    *** does not req: Tbet [KO]
    *** source: 19324016-Fig-2b
  *** IL4[Ab] secretion[ELISA] is increased irt anti-Cd3 (24 hr)
    *** cells: mSpTh2 in BMS
    *** does not req: Ripk2 [KO]
    *** source: 11894097-Fig-3c
  *** IL4[Ab] secretion[ELISA] is increased irt anti-Cd3 (24 hr)
    *** cells: mSpTh2 in BMS "OVA specific"
    *** source: 17088898-Fig-1a
  *** IL4[Ab] secretion[ELISA] is increased irt anti-Cd3 (72 hr)
    *** cells: mSpCs in BMS
    *** reqs: IL2Rg [KO]
    *** source: 10962026-Fig-3c
  *** IL4[Ab] secretion[ELISA] is increased irt anti-Cd3 (72 hr)
    *** cells: mSpCs<IL2Rg~null><xIL2Rg> in BMS
    *** inhibited by: xIL2Rg(1-290)"M1" [substitution]
    *** inhibited by: xIL2Rg(1-321)"M2" [substitution]
    *** source: 10962026-Fig-3c
  *** IL4[Ab] secretion[ELISA] is unchanged irt anti-Cd3 (24 hr)
    *** cells: mSpTh1 in BMS "OVA specific"
    *** source: 17088898-Fig-1a
  *** IL4[Ab] secretion[ELISA] is unchanged irt anti-Cd3 (24 hr)
    *** cells: mSpTh17 in BMS "OVA specific"
    *** source: 17088898-Fig-1a
  *** IL4[activity] secretion[IL4ActivityAssay] is increased irt anti-Cd3 (48 hr)
    *** cells: mSpTCs in BMS "pretreated with IL2 + anti-Cd3 + IL4 for 72 hr"
    *** comment: requires IL4 pretreatment [omission]
    *** comment: inhibited by IL12 pretreatment [substitution]
    *** source: 9759857-Fig-5a
*** IL5--
  *** IL5[Ab] secretion[ELISA] is increased irt anti-Cd3 (6 hr)
    *** cells: mSpCD4TCs in BMS "pretreated with anti-Cd3 + anti-Cd28 + IL4 for 5 days"
    *** partially reqs: Stat6 [KO]
    *** does not req: Tbet [KO]
    *** source: 19324016-Fig-2b
  *** IL5[Ab] secretion[ELISA] is increased irt anti-Cd3 (6 hr)
    *** cells: mSpCD4TCs in BMS "pretreated with anti-Cd3 + anti-Cd28 + IL12 for 5 days"
    *** reqs: Stat6 [KO]
    *** does not req: Tbet [KO]
    *** source: 19324016-Fig-2b
*** IL10Rb--
  *** IL10Rb-gene mRNA[RTPCR] is detectable-but unchanged irt anti-Cd3 (times)
    *** cells: hPBTCs in BMS
    *** times: 0+ 2+ 6+ 18+ hr
    *** source: 15308104-Fig-1a
*** IL12Rb2--
  *** IL12Rb2-gene mRNA[RPA] is increased irt anti-Cd3 (times)
    *** cells: hCBLs<Cd4~pos><Cd45ro~neg> in BMS
    *** times: 0+ 24++ 48++ 96+ hr
    *** enhanced by: IL12 [cotreatment]
    *** inhibited by: IL4 [cotreatment]
    *** source: 10037767-Fig-5
*** IL17a--
  *** IL17a-gene mRNA[RTPCR] is increased irt anti-Cd3 (24 hr)
    *** cells: EL4 in BMS
    *** inhibited by: xFoxp3 [addition]
    *** source: 18434325-Fig-3a
  *** IL17a-gene promo-reporter[Luc] is increased irt anti-Cd3 (24 hr)
    *** cells: EL4 in BMS
    *** inhibited by: xFoxp3 [addition]
    *** unaffected by: xFoxp3(mnr)"delExon2" [addition]
    *** unaffected by: xFoxp3(mnr)"delFKH" [addition]
    *** source: 18434325-Fig-4c
  *** IL17a-gene promo-reporter[Luc] is increased irt anti-Cd3 (24 hr)
    *** cells: EL4 in BMS
    *** source: 18434325-Fig-2a
  *** IL17a[Ab] secretion[ELISA] is increased irt anti-Cd3 (24 hr)
    *** cells: mSpTh17 in BMS "OVA specific"
    *** source: 17088898-Fig-1a
  *** IL17a[Ab] secretion[ELISA] is unchanged irt anti-Cd3 (24 hr)
    *** cells: mSpTh1 in BMS "OVA specific"
    *** source: 17088898-Fig-1a
  *** IL17a[Ab] secretion[ELISA] is unchanged irt anti-Cd3 (24 hr)
    *** cells: mSpTh2 in BMS "OVA specific"
    *** source: 17088898-Fig-1a
*** IL17f--
  *** IL17f-gene mRNA[RTPCR] is increased irt anti-Cd3 (5 hr)
    *** cells: mSpTh17 in BMS "OVA specific"
    *** source: 17088898-Fig-1a
  *** IL17f-gene mRNA[RTPCR] is increased irt anti-Cd3 (5 hr)
    *** cells: mSpTh17 in BMS "OVA specific"
    *** source: 17581589-Fig-1a
  *** IL17f-gene mRNA[RTPCR] is unchanged irt anti-Cd3 (5 hr)
    *** cells: mSpTh0 in BMS "OVA specific"
    *** source: 17581589-Fig-1a
  *** IL17f-gene mRNA[RTPCR] is unchanged irt anti-Cd3 (5 hr)
    *** cells: mSpTh1 in BMS "OVA specific"
    *** source: 17088898-Fig-1a
  *** IL17f-gene mRNA[RTPCR] is unchanged irt anti-Cd3 (5 hr)
    *** cells: mSpTh1 in BMS "OVA specific"
    *** source: 17581589-Fig-1a
  *** IL17f-gene mRNA[RTPCR] is unchanged irt anti-Cd3 (5 hr)
    *** cells: mSpTh2 in BMS "OVA specific"
    *** source: 17088898-Fig-1a
  *** IL17f-gene mRNA[RTPCR] is unchanged irt anti-Cd3 (5 hr)
    *** cells: mSpTh2 in BMS "OVA specific"
    *** source: 17581589-Fig-1a
*** IL18R1--
  *** IL18R1-gene mRNA[Northern] is detectable-but unchanged irt anti-Cd3 (4 hr)
    *** cells: mSpTh1 in BMS
    *** source: 11120802-Fig-4b
  *** IL18R1-gene mRNA[RTPCR] is unchanged irt anti-Cd3 (48 hr)
    *** cells: mSpTCs in BMS
    *** source: 9759857-Fig-4a
*** IL21--
  *** IL21-gene mRNA[RTPCR] is increased irt anti-Cd3 (5 hr)
    *** cells: mSpTh1 in BMS "OVA specific"
    *** source: 17581589-Fig-1a
  *** IL21-gene mRNA[RTPCR] is increased irt anti-Cd3 (5 hr)
    *** cells: mSpTh2 in BMS "OVA specific"
    *** source: 17581589-Fig-1a
  *** IL21-gene mRNA[RTPCR] is increased irt anti-Cd3 (5 hr)
    *** cells: mSpTh17 in BMS "OVA specific"
    *** source: 17581589-Fig-1a
  *** IL21-gene mRNA[RTPCR] is unchanged irt anti-Cd3 (5 hr)
    *** cells: mSpTh0 in BMS "OVA specific"
    *** source: 17581589-Fig-1a
*** IL22--
  *** IL22-gene mRNA[RTPCR] is increased irt anti-Cd3 (5 hr)
    *** cells: mSpTh17 in BMS "OVA specific"
    *** source: 17088898-Fig-1a
  *** IL22-gene mRNA[RTPCR] is increased irt anti-Cd3 (48 hr)
    *** cells: hPBMCs<Cd14~neg><Cd19~neg><Cd56~neg><Cd11a~neg><HlaDra~neg> in BMS
    *** enhanced by: ConA [cotreatment]
    *** source: 10875937-Fig-1
  *** IL22-gene mRNA[RTPCR] is increased irt anti-Cd3 (times)
    *** cells: hPBTCs in BMS
    *** times: 0 2+ 6++ 18++ hr
    *** source: 15308104-Fig-7b
  *** IL22-gene mRNA[RTPCR] is increased irt anti-Cd3 (tnr)
    *** cells: SPB21 in BMS
    *** source: 15120652-Fig-1
  *** IL22-gene mRNA[RTPCR] is unchanged irt anti-Cd3 (5 hr)
    *** cells: mSpTh1 in BMS "OVA specific"
    *** source: 17088898-Fig-1a
  *** IL22-gene mRNA[RTPCR] is unchanged irt anti-Cd3 (5 hr)
    *** cells: mSpTh2 in BMS "OVA specific"
    *** source: 17088898-Fig-1a
  *** IL22[Ab] secretion[ELISA] is increased irt anti-Cd3 (24 hr)
    *** cells: mSpTh1 in BMS "OVA specific"
    *** source: 17088898-Fig-1a
  *** IL22[Ab] secretion[ELISA] is increased irt anti-Cd3 (24 hr)
    *** cells: mSpTh17 in BMS "OVA specific"
    *** source: 17088898-Fig-1a
  *** IL22[Ab] secretion[ELISA] is unchanged irt anti-Cd3 (24 hr)
    *** cells: mSpTh2 in BMS "OVA specific"
    *** source: 17088898-Fig-1a
  *** IL22Ra1-gene mRNA[RTPCR] is unchanged irt anti-Cd3 (times)
    *** cells: hPBTCs in BMS
    *** times: 0 2 6 18 hr
    *** source: 15308104-Fig-1a
  *** IL22Ra1-gene mRNA[RTPCR] is unchanged irt anti-Cd3 (tnr)
    *** cells: SPB21 in BMS
    *** source: 15120652-Fig-1
*** Irf1--
  *** Irf1-gene mRNA[RPA] is increased irt anti-Cd3 (times)
    *** cells: hCBLs<Cd4~pos><Cd45ro~neg> in BMS
    *** times: 0+ 24++ 48++ 96+ hr
    *** enhanced by: IL12 [cotreatment]
    *** unaffected by: IL4 [cotreatment]
    *** source: 10037767-Fig-5
*** Jak1--
  *** Jak1[Ab] Yphos[pYAb-ppt] is unchanged irt anti-Cd3 (15 min)
    *** cells: hPHAblasts in BMS
    *** source: 7988557-Fig-2b
  *** Jak1[Ab]IP Yphos[pYAb] is unchanged irt anti-Cd3 (15 min)
    *** cells: hPHAblasts in BMS
    *** source: 7988557-Fig-2c
*** Jak3--
  *** Jak3[Ab]IP prot-exp[WB] is increased irt anti-Cd3 (times)
    *** cells: hPBMCs in BMS
    *** times: 0 24+ 48++ hr
    *** source: 9092570-Fig-4b
*** Kras--
  *** xKras[tAb] GTP-association[BDPD] is increased irt anti-Cd3 (times)
    *** cells: JURKAT<Pten~null> in BMLS
    *** times: 0 2+ 5+ min
    *** comment: xKras-splice-variant(2) (aka 4B, 2B, PO1118-2) is used
    *** source: 15226433(D)
*** Mras
  *** xMras[tAb] GTP-association[BDPD] is unchanged irt anti-Cd3 (times)
    *** cells: JURKAT<Pten~null> in BMLS
    *** times: 0 2 5 min
    *** source: 15226433(D)
*** Nras--
  *** xNras[tAb] GTP-association[BDPD] is increased irt anti-Cd3 (times)
    *** cells: JURKAT<Pten~null> in BMLS
    *** times: 0 2+ 5+ min
    *** source: 15226433(D)
*** Pxn--
  *** Pxn[Ab] copptby[WB] Fak2[Ab] is detectable-but unchanged irt anti-Cd3 (20 min)
    *** cells: AB1 in BMS
    *** source: 9488700-Fig-7
  *** Pxn[Ab] copptby[WB] Lck[Ab] is increased irt anti-Cd3 (20 min)
    *** cells: AB1 in BMS
    *** source: 9488700-Fig-3
  *** Pxn[Ab] snaggedby[WB] rLck(mnr)"SH2"[GST] is increased irt anti-Cd3 (20 min)
    *** cells: AB1 in BMS
    *** comment: snagged Pxn is phosed on tyrosine [pYAb]
    *** inhibited by: rLck(mnr)"SH3" [substitution]
    *** source: 9488700-Fig-5
  *** Pxn[Ab]IP Yphos[pYAb] is increased irt anti-Cd3 (20 min)
    *** cells: AB1 in BMS
    *** source: 9488700-Fig-2a
  *** Pxn[Ab]IP Yphos[pYAb] is increased irt anti-Cd3 (20 min)
    *** cells: AB1 in BMS
    *** times: 0+ 5++ 10+ min
    *** comment: antibody was cross-linked instead of bound to plate
    *** bkg inhibited by: PP1 [cotreatment]
    *** source: 9488700-Fig-8
  *** Pxn[Ab]IP Yphos[pYAb] is increased irt anti-Cd3 (20 min)
    *** cells: JURKAT<Pten~null> in BMS
    *** times: 0 2+ 5++ 10+ min
    *** reqs: Lck [KO]
    *** source: 9488700-Fig-9
*** Raf1--
  *** Raf1-gene mRNA[Northern] is increased irt anti-Cd3 (times)
    *** cells: hPBMCs in BMHIS
    *** times: 0 6+ 48++ hr
    *** unaffected by: CsA + IL2 [cotreatment]
    *** comment: inhibited by CsA cotreatment at 48 hr only
    *** comment: unaffected by CHX cotreatment at 6 hr (ND at 48 hr)
    *** comment: no control for total RNA
    *** source: 1708096-Table-1
  *** Raf1-gene mRNA[Northern] is increased irt anti-Cd3 (times)
    *** cells: hPBMCs in BMHIS
    *** times: 0+ 3+ 6+ 12++ 24++ 36++ 48++ 120+ hr
    *** comment: no control for total RNA
    *** source: 1708096-Fig-1a
  *** Raf1[Ab] phos[WBMS] is increased irt anti-Cd3 (times)
    *** cells: hPBMCs in BMHIS
    *** times: 0 3+ 6++ 12 24+ 36+++ 48+++ 72+++ 96++ 120+ hr
    *** source: 1708096-Fig-1d
  *** Raf1[Ab] phos[WBMS] is unchanged irt anti-Cd3 (times)
    *** cells: hIL2RTCs in BMHIS "IL2-deprived for 12-14 hr"
    *** times: 0 5 15 60 min
    *** source: 1708096-Fig-3b
  *** Raf1[Ab] phos[WBMS] is unchanged irt anti-Cd3 (times)
    *** cells: hPBMCs in BMHIS
    *** times: 0 5 15 30 min
    *** source: 1708096-Fig-3a
  *** Raf1[Ab]IP IVKA(auto)[32P-ATP] is increased irt anti-Cd3 (48 hr)
    *** cells: hPBMCs in BMHIS
    *** comment: no control for total Raf1 protein
    *** source: 1708096-Fig-4a
*** RasGrp1--
  *** RasGrp1[Ab] infraction(cytoplasmic)[WB] is decreased irt anti-Cd3 (times)
    *** cells: JURKATT in BMS
    *** times: 0++ 5+ 30+ 60+ 90+ 120+ min
    *** source: 10807788-Fig-3b
  *** RoRc-gene mRNA[RTPCR] is detectable-but unchanged irt anti-Cd3 (24 hr)
    *** cells: EL4 in BMS
    *** source: 18434325-Fig-3a
*** Stat1--
  *** Stat1[Ab] snaggedby[WB] oligo[biotin] is unchanged irt anti-Cd3 (15 min)
    *** cells: hPHAblasts in BMS
    *** oligo: "FcgR-GAS" 5-GTATTTCCCAGAAAAGGAAC-3
    *** source: 7988557-Fig-9b
*** Stat3--
  *** Stat3[Ab] snaggedby[WB] oligo[biotin] is unchanged irt anti-Cd3 (15 min)
    *** cells: hPHAblasts in BMS
    *** oligo: "FcgR-GAS" 5-GTATTTCCCAGAAAAGGAAC-3
    *** source: 7988557-Fig-9c
*** Stat4--
  *** Stat4[Ab]IP Yphos[pYAb] is unchanged irt anti-Cd3 (30 min)
    *** cells: 3F6 in BMS
    *** source: 10097133-Fig-1b
*** DNA-synthesis--
  *** DNA-synthesis[3H-Thymidine] is increased irt anti-Cd3 (3 days)
    *** cells: hPBMCs in BMS
    *** unaffected by: IL10 [cotreatment]
    *** source: 10637267-Fig-3a
  *** DNA-synthesis[3H-Thymidine] is increased irt anti-Cd3 (18 hr)
    *** cells: mSpCs in BMS
    *** does not req: Stat5a [KO]
    *** partially reqs: Stat5b [KO]
    *** reqs: Stat5a and/or Stat5b [DKO]
    *** source: 10072077-Fig-3a
  *** DNA-synthesis[3H-Thymidine] is increased irt anti-Cd3 (26 hr)
    *** cells: mTCs in BMS
    *** partially inhibited by: xIkba(mnr)"del-Nterm" [addition]
    *** source: 11160275-Fig-8
  *** DNA-synthesis[3H-Thymidine] is increased irt anti-Cd3 (40 hr)
    *** cells: mTCs in BMS
    *** inhibited by: xIkba(mnr)"del-Nterm" [addition]
    *** source: 11160275-Fig-1b
  *** DNA-synthesis[3H-Thymidine] is increased irt anti-Cd3 (40 hr)
    *** cells: mTCs in BMS
    *** unaffected by: IL2 [cotreatment]
    *** unaffected by: IL4 [cotreatment]
    *** source: 11160275-Fig-1b
  *** DNA-synthesis[3H-Thymidine] is increased irt anti-Cd3 (48 hr)
    *** cells: mSpTCs<Cd4~pos> in BMS
    *** partially reqs: Ripk2 [KO]
    *** source: 11894097-Fig-2d
  *** DNA-synthesis[3H-Thymidine] is increased irt anti-Cd3 (56 hr)
    *** cells: mTCs in BMS
    *** unaffected by: IL12 [cotreatment]
    *** source: 11160275-Fig-8
  *** DNA-synthesis[3H-Thymidine] is unchanged irt anti-Cd3 (88 hr)
    *** cells: mThyCs in BMS
    *** source: 10962026-Fig-3a
*** Tyk2--
  *** Tyk2[Ab] Yphos[pYAb-ppt] is unchanged irt anti-Cd3 (15 min)
    *** cells: hPHAblasts in BMS
    *** source: 7988557-Fig-2b
  *** Tyk2[Ab]IP Yphos[pYAb] is unchanged irt anti-Cd3 (15 min)
    *** cells: hPHAblasts in BMS
    *** source: 7988557-Fig-2c
*** Vav1--
  *** xVav1[Ab]IP phos(Y174)[phosAb] is increased irt anti-Cd3 (times)
    *** cells: JURKAT<Pten~null> in BMLS
    *** times: 0 2++ 5+ 10 min
    *** source: 10669745-Fig-9c
  *** xVav1[Ab]IP phos(Y174)[phosAb] is increased irt anti-Cd3 (times)
    *** cells: JURKAT<Pten~null> in BMLS "Triton-soluble-fraction"
    *** times: 0 1++ 2++ 5++ 10+ 30+ min
    *** source: 10669745-Fig-9c
  *** xVav1[Ab]IP Yphos[pYAb] is increased irt anti-Cd3 (times)
    *** cells: JURKAT<Pten~null> in BMLS
    *** times: 0 2++ 5+ 10 min
    *** source: 10669745-Fig-9c
*** Vav3--
  *** Vav3[Ab]IP Yphos[pYAb] is increased irt anti-Cd3 (times)
    *** cells: JURKAT<Pten~null> in BMS
    *** times: 0 2+ 5+ 10+ min
    *** source: 10523675-Fig-2c
