===========================
Semi-Direct Phosphorylation
===========================

  *** rIkk2(170-190)[32P] phos[32P-ATP] is increased by xMekk3[tAb]IP
    *** cells: none
    *** inhibited by: rIkk2((170-190)/S177A/S181A) [substitution]
    *** source: 14636585(D)
  *** rIkk2[32P] phos[32P-ATP] is increased by xMekk3[tAb]IP
    *** cells: COS1 in BMS
    *** inhibited by: xMekk3(mnr)"KD" [substitution]
    *** source: 11429546-Fig-3d

===============
Phosphorylation
===============

  *** Ikk2[phosAb] phos(S181)[phosAb] is increased itpo xMekk3
    *** cells: HEK293 in BMS
    *** inhibited by: xMekk3(K391A)"KD" [substitution]
    *** source: 15572679-Fig-9

=================
Kinase Activation
=================

  *** Ikk2[Ab]IP IVKA(Ikba)[32P-ATP] is increased itpo xMekk3
    *** cells: mEFs in BMS
    *** does not req: Ripk1 [KO]
    *** source: 11429546-Fig-3e
  *** Ikk2[Ab]IP IVKA(Ikba)[32P-ATP] is increased itpo xMekk3
    *** cells: mEFs in BMS
    *** does not req: Traf2 [KO]
    *** source: 11429546-Fig-3e
  *** Ikk2[Ab]IP IVKA(Ikba)[32P-ATP] is detectable
    *** cells: mEFs in BMS
    *** reqs: Mekk3 [KO]
    *** source: 14661019-Fig-3e
  *** xIkk2[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xMekk3
    *** cells: HELA in BMS
    *** source: 10085062-Fig-2b
  *** xIkk2[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xMekk3
    *** cells: HELA in BMS
    *** source: 10085062-Fig-3b



