Irak1--

  *** Rela[phosAb] phos(S536)[phosAb] is increased irt IL1b (times)
    *** cells: mEFs in BMS
    *** times: 0 15+ 30+ min
    *** inhibited by: Irak4(K213A/K214A)"KD" [substitution]
    *** source: 17337443-Fig-3a

Ikba--  ???

  *** Rela[phosAb] phos(S536)[phosAb] is increased irt IL1b (15 min)
    *** cells: HELA in BMS
    *** unaffected by: xIkba(mnr)"SuperRepressor" [addition]
    *** source: 16046471-Fig-4b

Ikke--  ???

  *** xRela[phosAb] phos(S536)[phosAb] is increased irt IL1 (10 min)
    *** cells: HEK293<xIL1R1> in BMS
    *** enhanced by: xIkke [addition]
    *** inhibited by: xIkke(mnr)"KD" [addition]
    *** source: 15489227-Fig-5a

Tak1--

  *** Rela[phosAb] phos(S536)[phosAb] is increased irt IL1b (times)
    *** cells: mEFs<Tak1~null><xTak1> in BMS
    *** times: 0 5++ 10+ 15+ 30 min
    *** partially reqs: xTak1 [omission]
    *** partially inhibited by: xTak1(T178A/T184A) [substitution]
    *** source: 18617512-Fig-4d

not Tbk1--

  *** xRela[phosAb] phos(S536)[phosAb] is increased irt IL1 (10 min)
    *** cells: HEK293<xIL1R1> in BMS
    *** unaffected by: xTbk1 [addition]
    *** unaffected by: xTbk1(mnr)"KD" [addition]
    *** source: 15489227-Fig-5a

not Traf2-- or Traf5--

  *** Rela[phosAb] phos(S536)[phosAb] is increased irt IL1b (10 min)
    *** cells: mEFs in BMS
    *** does not req: Traf2 or Traf5 [DKO]
    *** source: 12842894-Fig-4

other--

  *** Rela[Ab]IP phos[32Pi] is increased irt IL1 (10 min)
    *** cells: mEFs in BMS
    *** source: 11684013-Fig-4a
  *** Rela[phosAb] phos(S536)[phosAb] is increased irt IL1a (times)
    *** cells: HELA in BMS
    *** times: 0 10++ 30+ min
    *** unaffected by: PD98059 [addition]
    *** unaffected by: SP600125 [addition]
    *** unaffected by: SB203580 [addition]
    *** unaffected by: Wortmannin [addition]
    *** source: 15489227(D)
  *** xRela[phosAb] phos(S536)[phosAb] is increased irt IL1b (15 min)
    *** cells: mEFs<Rela~null><xRela> in BMS
    *** unaffected by: xRela(S468A) [substitution]
    *** source: 16046471-Fig-5a

=======================
Phosphorylation on S468
=======================

  *** Rela[phosAb] phos(S468)[phosAb] is detectable-but unchanged irt IL1b (15 min)
    *** cells: SKW64 in BMS
    *** source: 16046471-Fig-3b
  *** Rela[phosAb] phos(S468)[phosAb] is increased irt IL1b (15 min)
    *** cells: HELA in BMS
    *** source: 16046471-Fig-3b
  *** Rela[phosAb] phos(S468)[phosAb] is increased irt IL1b (15 min)
    *** cells: MCF7 in BMS
    *** source: 16046471-Fig-3b
  *** Rela[phosAb] phos(S468)[phosAb] is increased irt IL1b (15 min)
    *** cells: HEP3B in BMS
    *** source: 16046471-Fig-3b
  *** Rela[phosAb] phos(S468)[phosAb] is increased irt IL1b (15 min)
    *** cells: U251 in BMS
    *** source: 16046471-Fig-3b
  *** Rela[phosAb] phos(S468)[phosAb] is increased irt IL1b (15 min)
    *** cells: HELA in BMS
    *** unaffected by: xIkk1(mnr)"DN" [addition]
    *** source: 16046471-Fig-4a
  *** Rela[phosAb] phos(S468)[phosAb] is increased irt IL1b (15 min)
    *** cells: HELA in BMS
    *** inhibited by: xIkk2(mnr)"DN" [addition]
    *** source: 16046471-Fig-4a
  *** Rela[phosAb] phos(S468)[phosAb] is increased irt IL1b (15 min)
    *** cells: HELA in BMS
    *** unaffected by: xIkba(mnr)"SuperRepressor" [addition]
    *** source: 16046471-Fig-4a
  *** Rela[phosAb] phos(S468)[phosAb] is increased irt IL1b (15 min)
    *** cells: HELA in BMS
    *** inhibited by: PS1145 [pretreatment]
    *** unaffected by: SB203580 [pretreatment]
    *** unaffected by: PD98059 [pretreatment]
    *** unaffected by: LY294002 [pretreatment]
    *** unaffected by: SP600125 [pretreatment]
    *** unaffected by: GSK3inhibitorI [pretreatment]
    *** source: 16046471-Fig-4d
  *** xRela[phosAb] phos(S468)[phosAb] is increased irt IL1b (15 min)
    *** cells: mEFs<Rela~null><xRela> in BMS
    *** inhibited by: xRela(S468A) [substitution]
    *** source: 16046471-Fig-5a
  *** Rela[phosAb] phos(S468)[phosAb] is unchanged irt IL1b (15 min)
    *** cells: JURKAT<Pten~null> in BMS
    *** source: 16046471-Fig-3b
  *** Rela[phosAb] phos(S468)[phosAb] is increased irt IL1b (times)
    *** cells: HELA in BMS
    *** times: 0 7+++ 15++ 30+ 60 120 min
    *** enhanced by: CalyculinA [pretreatment]
    *** source: 16046471-Fig-3a
