Mef2c is phosed on S387/T293/T300 irt Lps

  *** xMef2c(TAD)[tAb]IP phos[32Pi] is increased irt Lps (2 hr)
    *** cells: RAW2647 in BMS
    *** partially inhibited by: xMef2c(TAD/S387A) [substitution]
    *** partially inhibited by: xMef2c(TAD/T293A/T300A) [substitution]
    *** source: 9069290-Fig-3c

Mef2c activation requires phosphorylation on S387/T293/T300

  *** xMef2c(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased irt Lps (8 hr)
    *** cells: RAW2647 in BMS
    *** inhibited by: xMef2c(TAD/S387A) [substitution]
    *** unaffected by: xMef2c(TAD/S387A) [substitution]
    *** inhibited by: xMef2c(TAD/T293A/T300A) [substitution]
    *** source: 9069290-Fig-3e

Mef2c activation requires P38

  *** xMef2c(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased irt Lps (8 hr)
    *** cells: RAW2647 in BMS
    *** inhibited by: xP38?(K63M)"DN" [addition]
    *** source: 9069290-Fig-2d

other

  *** Mef2s[RE] oligo-binding[EMSA] is increased irt Lps (times)
    *** cells: RAW2647 in BMS
    *** times: 0  30+ 60++ 120++ 300+ min
    *** source: 9069290-Fig-2b
  *** xMef2c(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased irt Lps (8 hr)
    *** cells: THP1 in BMS
    *** bkg inhibited by: SB202190 [addition]
    *** source: 9069290-Fig-2c

