=========================
Coprecipitation with TLR4
=========================

  *** Ciap2[Ab] copptby[WB] TLR4[Ab] is increased irt Lps (times)
    *** cells: RAW2647 in BMS "membrane fraction"
    *** times: 0 10+ 30 min
    *** comment: decrease at 30 min reqs Traf6 [RNAi]
    *** comment: decrease at 30 min does not req Traf3 [RNAi]
    *** source: 19898473-Fig-2c

not Myd88--  ???

  *** Ciap2[Ab] copptby[WB] TLR4[Ab] is increased irt Lps (times)
    *** cells: mBMMs<Myd88~null> in BMS "membrane fraction"
    *** times: 0 10+ 30+ min
    *** source: 19898473-Fig-S3a


not Trif--

  *** Ciap2[Ab] copptby[WB] TLR4[Ab] is increased irt Lps (times)
    *** cells: mBMMs<Trif~fmut> in BMS "membrane fraction"
    *** times: 0 10+ 30 min
    *** source: 19898473-Fig-S3a

  *** Ciap2[Ab] copptby[WB] TLR4[Ab] is increased irt Lps (times)
    *** cells: mBMMs in BMS "membrane fraction"
    *** times: 0 10+ 30 min
    *** inhibited by: SmacMimetic [pretreatment]
    *** source: 19898473-Fig-2a
  *** Ciap2[Ab] copptby[WB] TLR4[Ab] is increased irt Lps (times)
    *** cells: RAW2647 in BMS "membrane fraction"
    *** times: 0 10+ min
    *** unaffected by: Dynasore [pretreatment]
    *** source: 19898473-Fig-S4b

==============================================
Association with other members of TLR4 complex
==============================================

  *** Ciap2[Ab] copptby[WB] Tak1[Ab] is increased irt Lps (times)
    *** cells: mBMMs in BMS "cytosolic fraction"
    *** times: 0 10+ 30+ min
    *** inhibited by: SmacMimetic [pretreatment]
    *** source: 19898473-Fig-2a

========
Location
========

  *** Ciap2[Ab] infraction(endosomal)[WB] is unchanged irt Lps (times)
    *** cells: RAW2647 in BMS
    *** times: 0 30 60 min
    *** unaffected by: SmacMimetic [pretreatment]
    *** unaffected by: Dynasore [pretreatment]
    *** source: 19898473-Fig-4b
  *** Ciap2[Ab]IP infraction(cytosolic)[WB] is detectable-but unchanged irt Lps (times)
    *** cells: mBMMs in BMS
    *** times: 0+ 10+ 30+ min
    *** source: 19898473-Fig-S4a
  *** Ciap2[Ab]IP infraction(membrane)[WB] is increased irt Lps (times)
    *** cells: mBMMs in BMS
    *** times: 0 10+ 30 min
    *** source: 19898473-Fig-S4a
