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Phosphorylation on S1981
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Mre11-- and/or Rad50--

  *** Atm[phosAb] phos(S1981)[phosAb] is increased irt NCS (times)
    *** cells: hLymphoblasts in BMS
    *** times: 0+ 5++ 15++ 30++ 60++ min
    *** reqs: Mre11 and/or Rad50 [fmut]
    *** source: 14532133-Fig-2b
  *** Atm[phosAb] phos(S1981)[phosAb] is increased irt NCS (times)
    *** cells: hLymphoblasts<Nbs1~null><xNbs1><Mre11~null><xMre11><Rad50~null><xRad50> in BMS
    *** times: 0 10++ 30++ min
    *** reqs: xNbs1 and/or xMre11 and/or xRad50 [omission]
    *** source: 14532133-Fig-6b

Nbs1--

  *** Atm[phosAb] phos(S1981)[phosAb] is increased irt NCS (times)
    *** cells: hLymphoblasts in BMS
    *** times: 0+ 5++ 15++ 30++ 60++ min
    *** partially reqs: Nbs1 [fmut]
    *** source: 14532133-Fig-2b
  *** Atm[phosAb] phos(S1981)[phosAb] is increased irt NCS (times)
    *** cells: hLymphoblasts<Nbs1~null><xNbs1> in BMS
    *** times: 0 10++ 30++ 60+ min
    *** partially reqs: xNbs1 [omission]
    *** source: 14532133-Fig-6c

no Trim28--

  *** Atm[phosAb] phos(S1981)[phosAb] is increased irt NCS (30 min)
    *** cells: U2OS<Trim28~kd><xTrim28> in BMS
    *** does not req: xTrim28 [omission]
    *** unaffected by: xTrim28(S824A) [substitution]
    *** unaffected by: xTrim28(S824D) [substitution]
    *** source: 16862143-Fig-S5b

chemicals

  *** Atm[phosAb] phos(S1981)[phosAb] is increased irt NCS (10 min)
    *** cells: U2OS<xMdm4> in BMS
    *** partially inhibited by: Wortmannin [pretreatment]
    *** inhibited by: KU55933 [pretreatment]
    *** source: 15788536-Fig-9

no extras

  *** Atm[phosAb] phos(S1981)[phosAb] is increased irt NCS (30 min)
    *** cells: U2OS in BMS
    *** source: 16862143-Fig-S5b

