  ***  xFoxp3[tAb] copptby[WB] xRoRc[Ab] is detectable
    *** cells: HEK293T<xRoRc><xFoxp3> in BMS
    *** inhibited by: xFoxp3(mnr)"exon2-deleted" [substitution]
    *** source: 18368049-Fig-3b
*** A2m--
  *** A2m-gene promo-reporter[Luc] is increased itpo xFoxo1
    *** cells: HEPG2 in BMS "treated with IL6"
    *** inhibited by: xFoxo1(1-357) [substitution]
    *** partially inhibited by: xFoxo1(1-505) [substitution]
    *** partially inhibited by: xFoxo1(1-560) [substitution]
    *** partially inhibited by: xFoxo1(1-639) [substitution]
    *** source: 12456685-Fig-4f
*** Abl1--
  *** Abl1[Ab] copptby[WB] CrkL[Ab] is detectable
    *** cells: 32D in BMS
    *** source: 8978605-Fig-6c
  *** xAbl1[Ab] copptby[WB] xDok2[Ab] is detectable
    *** cells: COS1<xDok2><xAbl1> in BMLS
    *** partially inhibited by: xAbl1(mnr)"KD" [substitution]
    *** inhibited by: xAbl1(mnr)"dSH2" [substitution]
    *** source: 12777393-Fig-3a
  *** Abl1[Ab] snaggedby[WB] rCrk[GST] is detectable
    *** cells: 32D in BMS
    *** source: 8978605-Fig-3
  *** Abl1[Ab] snaggedby[WB] rCrkL[GST] is detectable
    *** cells: 32D in BMS
    *** source: 8978605-Fig-3
  *** xAbl1[Ab]IP Yphos[pYAb] is detectable
    *** cells: COS1<xAbl1> in BMS
    *** inhibited by: xAbl1(mnr)"KD" [substitution]
    *** partially inhibited by: xAbl1(mnr)"dSH2" [substitution]
    *** source: 12777393-Fig-3a
*** Abl2--
  *** xAbl2[tAb] copptby[WB] xHras(G12V)[Ab] is increased itpo xRin1
    *** cells: HEK293T<xAbl2> in BMS
    *** source: 15886098-Fig-6a
*** Accs--
  *** Accs[phosAb] phos(MSGLH)[phosAb] is decreased itpo xAkt1(myr)"CA"
    *** cells: mEFs<Tsc2~null> in BMS
    *** source: 16027121-Fig-6c
  *** Accs[phosAb] phos(MSGLH)[phosAb] is detectable
    *** cells: mEFs<Lkb1~null> in BMS
    *** enhanced by: xLkb1 [addition]
    *** source: 19187764-Fig-5a
  *** Accs[phosAb] phos(MSGLH)[phosAb] is detectable
    *** cells: mEFs<Lkb1~null><xLkb1> in BMS
    *** enhanced by: xLkb1(S428A) [substitution]
    *** enhanced by: xLkb1(S325A) [substitution]
    *** enhanced by: xLkb1(S325A/S428A) [substitution]
    *** source: 19187764-Fig-5a
  *** Accs[phosAb] phos(MSGLH)[phosAb] is detectable
    *** cells: mHepatocytes in BMS
    *** reqs: Lkb1 [KO]
    *** source: 18439900-Fig-S2
  *** Accs[phosAb] phos(MSGLH)[phosAb] is detectable
    *** cells: SKMEL28<xLkb1> in BMS
    *** unaffected by: xLkb1(S428A) [substitution]
    *** enhanced by: xLkb1(S325A) [substitution]
    *** enhanced by: xLkb1(S325A/S428A) [substitution]
    *** source: 19187764-Fig-5b
  *** Accs[phosAb] phos(MSGLH)[phosAb] is increased itao Akt1 and Akt2 [DKO]
    *** cells: mEFs in BMLS
    *** source: 16027121-Fig-2d
  *** Accs[phosAb] phos(MSGLH)[phosAb] is increased itao Cav1 [RNAi]
    *** cells: bAECs in BMLS
    *** source: 17519230(D)
  *** Accs[phosAb] phos(MSGLH)[phosAb] is increased itao Tsc2 [KO]
    *** cells: mEFs in BMS
    *** source: 16027121-Fig-6c
  *** Accs[phosAb] phos(MSGLH)[phosAb] is increased itpo xCamkk2
    *** cells: CCL13 in BMS
    *** inhibited by: xCamkk2(D329A)"KD" [substitution]
    *** source: 16054096(D)
  *** Accs[phosAb] phos(MSGLH)[phosAb] is increased itpo xLkb1
    *** cells: UACC257 in BMS
    *** enhanced by: xLkb1(S325A/S428A) [addition]
    *** source: 19187764-Fig-S11
  *** Accs[phosAb] phos(MSGLH)[phosAb] is increased itpo xLkb1(S325A/S428A)
    *** cells: CHO in BMS
    *** inhibited by: xLkb1(WT) [substitution]
    *** source: 19187764-Fig-S11
  *** Accs[phosAb] phos(MSGLH)[phosAb] is increased itpo xMap4k4
    *** cells: rNCMs in BMS
    *** inhibited by: xTak1(K63W)"DN" [addition]
    *** source: 17085580(D)
  *** Accs[phosAb] phos(MSGLH)[phosAb] is undetectable
    *** cells: HELA in BMS
    *** unaffected by: xLkb1 [addition]
    *** unaffected by: xLkb1(S428A) [addition]
    *** enhanced by: xLkb1(S325A) [addition]
    *** enhanced by: xLkb1(S325A/S428A) [addition]
    *** source: 19187764-Fig-S10
  *** Accs[phosAb] phos(S73)[phosAb] is decreased itpo xAkt1(myr)"CA"
    *** cells: rNCMs in BMS
    *** source: 12890675(D)
  *** Accs[phosAb] phos(S73)[phosAb] is decreased itpo xAkt2(myr)"CA"
    *** cells: rNCMs in BMS
    *** source: 12890675(D)
*** Ack2--
  *** xAck2[tAb] copptby[WB] xCdc42(Q61L)[tAb] is detectable
    *** cells: COS7<xSrc><xAck2> in BMS
    *** unaffected by: xSrc(Y530F) [substitution]
    *** source: 14506284-Fig-3l
*** Actb--
  *** Actb[Ab] colocwith[IHC] Stau1[Ab] is detectable
    *** cells: SHSY5Y in BMS "differentiated with retinoic acid for 7 days"
    *** source: 15121898(D)
  *** Actb[Ab] copptby[WB] xStau1[tAb] is detectable
    *** cells: HEK293T in BMS "infected with vaccinia vTf7-3 virus"
    *** source: 15121898(D)
*** Actin--
  *** Actin[Ab] copptby[WB] xEps8[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 14565974-Fig-4a
  *** Actin[Ab] copptby[WB] xEps8l1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 14565974-Fig-4a
  *** Actin[Ab] copptby[WB] xEps8l2[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 14565974-Fig-4a
  *** Actin[Ab] copptby[WB] xEps8l3[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 14565974-Fig-4a
*** AcvR1--
  *** xAcvR1[tAb] copptby[WB] xZfyve16[tAb] is undetectable
    *** cells: HEK293T<xAcvR1> in BMS
    *** source: 17272273-Fig-4d
  *** xAcvR1[tAb]IP cleavage[WB] is unchanged itpo xAdam17
    *** cells: CHO<xAcvR1> in BMLS
    *** source: 19595713-Fig-3d
  *** xAcvR1b[tAb] copptby[WB] xZfyve16[tAb] is detectable
    *** cells: HEK293T<xAcvR1b> in BMS
    *** source: 17272273-Fig-4d
  *** xAcvR1b[tAb]IP cleavage[WB] is unchanged itpo xAdam17
    *** cells: CHO<xAcvR1b> in BMLS
    *** source: 19595713-Fig-3d
  *** xAcvR2[tAb]IP IVKA(Smad1)[32P-ATP] is unchanged itpo xAcvR1
    *** cells: COS1<xAcvR2> in BMS "treated with Bmp7 (30 min)"
    *** source: 9748228(D)
  *** xAcvR2b[tAb]IP IVKA(Smad1)[32P-ATP] is increased itpo xBmpR1b
    *** cells: COS1<xAcvR2b> in BMS "treated with Bmp2 (30 min)"
    *** source: 9748228(D)
  *** xAcvR2b[tAb]IP IVKA(Smad1)[32P-ATP] is unchanged itpo xAcvR1
    *** cells: COS1<xAcvR2b> in BMS "treated with Bmp7 (30 min)"
    *** source: 9748228(D)
  *** xAcvRl1[Ab] copptby[WB] xEng[tAb] is detectable
    *** cells: COS1<xAcvRl1> in BMS
    *** source: 10187774(D)
  *** xAcvRl1[tAb] copptby[WB] xZfyve16[tAb] is detectable
    *** cells: HEK293T<xAcvRl1> in BMS
    *** source: 17272273-Fig-4d
  *** xAcvRl1[tAb]IP cleavage[WB] is unchanged itpo xAdam17
    *** cells: CHO<xAcvRl1> in BMLS
    *** source: 19595713-Fig-3d
  *** xAdam10[tAb] oligomerization[2TagPpt] is detectable
    *** cells: CHO<xProTgfa><xAdam10> in BMS
    *** source: 22550340-Fig-S2a
  *** xAdam17[tAb] copptby[WB] xAcvR1[tAb] is undetectable
    *** cells: HEPG2<xAdam17><xAcvR1> in BMS
    *** source: 22550340-Fig-1c
  *** xAdam17[tAb] copptby[WB] xAdam10[tAb] is undetectable
    *** cells: HEPG2<xAdam17><xAdam10> in BMS
    *** source: 22550340-Fig-1c
  *** xAdam17[tAb] copptby[WB] xTgfbR2[tAb] is undetectable
    *** cells: CHO<xProTgfa><xAdam10><xTgfbR2> in BMS
    *** source: 22550340-Fig-S2a
  *** xAdam17[tAb] copptby[WB] xTgfbR2[tAb] is undetectable
    *** cells: HEPG2<xAdam17><xTgfbR2> in BMS
    *** source: 22550340-Fig-1c
  *** xAdam17[tAb] oligomerization[2TagPpt] is detectable
    *** cells: CHO<xProTgfa><xAdam17> in BMS
    *** source: 22550340-Fig-4a
  *** xAdam17[tAb] oligomerization[2TagPpt] is detectable
    *** cells: HEK293<xAdam17> in BMS
    *** inhibited by: xAdam17(mnr)"delCytoDomain" [substitution]
    *** source: 22550340-Fig-3b
  *** xAdam17[tAb] oligomerization[2TagPpt] is detectable
    *** cells: HEPG2<xAdam17> in BMS
    *** source: 22550340-Fig-1c
  *** xAdam17[tAb] oligomerization[2TagPpt] is detectable
    *** cells: HEPG2<xAdam17> in BMS
    *** source: 22550340-Fig-S3b
  *** xAdam17[tAb]IP IVProteaseAct(peptide)[FRET] is detectable
    *** cells: CHO<xProTgfa> in BMS
    *** inhibited by: xAdam17(mnr)"CysteineTrap" [substitution]
    *** source: 22550340-Fig-5d
  *** xAdrbk1[Ab] copptby[WB] xGit1[tAb] is detectable
    *** cells: COS7<xAdrbk1><xGit1> in BMS
    *** source: 10896954-Fig-5
  *** xAdrbk1[Ab] copptby[WB] xGit2-short[tAb] is detectable
    *** cells: COS7<xAdrbk1><xGit2-short> in BMS
    *** source: 10896954-Fig-5
  *** xAdrbk1[Ab] copptby[WB] xGit2[tAb] is detectable
    *** cells: COS7<xAdrbk1><xGit2> in BMS
    *** source: 10896954-Fig-5
*** Agl--
  *** xAgl[tAb] copptby[WB] xAmpka1[tAb] is detectable
    *** cells: COS7<xAgl> in BMS
    *** source: 15886229(D)
  *** xAgl[tAb] copptby[WB] xAmpka2[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 15886229(D)
  *** xAgl[tAb] copptby[WB] xAmpkb1[tAb] is detectable
    *** cells: COS7 in BMS
    *** unaffected by: xAmpkb1(W100G/K128Q)"glycogen-binding-mut" [substitution]
    *** source: 15886229(D)
  *** xAgl[tAb] copptby[WB] xAmpkb2[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 15886229(D)
  *** xAgl[tAb] copptby[WB] xAmpkg1[tAb] is undetectable
    *** cells: COS7 in BMS
    *** source: 15886229(D)
  *** xAgl[tAb] copptby[WB] xAmpkg2[tAb] is undetectable
    *** cells: COS7 in BMS
    *** source: 15886229(D)
*** Aicda--
  *** Aicda-gene mRNA[RTPCR] is detectable
    *** cells: mSpBCs in BMS "treated with anti-Cd40 (24 hr)"
    *** partially inhibited by: kMekk1(1-1188)"del-kinase-domain" [addition]
    *** source: 17143273-Fig-6c
  *** rAkt1 IVKA(Tsc2)(S939)[phosAb] is increased by xIkke[tAb]IP
    *** cells: none
    *** IPfrom: HEK293<xIkke> in BMS
    *** inhibited by: xIkke(mnr)"KD" [substitution]
    *** source: 21464307-Fig-3c
*** Akt1--
  *** xAkt1(myr)[Ab]IP IVKA(Tsc2)[32P-ATP] is detectable
    *** cells: HELA in BMS
    *** inhibited by: rTsc2(S939A) [substitution]
    *** inhibited by: rTsc2(S981A) [substitution]
    *** inhibited by: rTsc2(S993A) [substitution]
    *** inhibited by: rTsc2(S1130A) [substitution]
    *** inhibited by: rTsc2(S1132A) [substitution]
    *** inhibited by: rTsc2(S1462A) [substitution]
    *** inhibited by: rTsc2(S1798A) [substitution]
    *** source: 12167664-Fig-1b
  *** xAkt1(myr)[phosAb] phos(T308)[phosAb] is detectable
    *** cells: COS7<xAkt1(myr)> in BMS
    *** inhibited by: xYwhaq [addition]
    *** inhibited by: xYwhah [addition]
    *** source: 12177059-Fig-4d
  *** rAkt1[Ab] boundby[WB] rPlcg1(mnr)"SH3"[GST] is detectable
    *** cells: none
    *** source: 16525023-Fig-3c
  *** Akt1[Ab] copptby[WB] Tsc2[Ab] is detectable
    *** cells: HELA in BMS
    *** source: 12167664-Fig-2a
  *** xAkt1[Ab] copptby[WB] xTsc1[tAb] is detectable
    *** cells: HEK293T<xTsc1><xTsc2><xAkt1> in BMS
    *** reqs: xTsc2 [omission]
    *** source: 12167664-Fig-2b
  *** xAkt1[Ab] copptby[WB] xTsc2[tAb] is detectable
    *** cells: HEK293<xTsc1><xTsc2><xAkt1> in BMLS
    *** source: 15342917-Fig-3a
  *** xAkt1[Ab] copptby[WB] xYwhab[tAb] is detectable
    *** cells: HEK293T<xYwhab><xAkt1> in BMS
    *** source: 12177059-Fig-1d
  *** xAkt1[Ab] copptby[WB] xYwhaq[tAb] is detectable
    *** cells: HEK293T<xYwhaq><xAkt1> in BMS
    *** source: 12177059-Fig-1d
  *** xAkt1[Ab] copptby[WB] xYwhaz[tAb] is detectable
    *** cells: HEK293T<xYwhaz><xAkt1> in BMS
    *** source: 12177059-Fig-1d
  *** Akt1[Ab] infraction(S100)[WB] is detectable
    *** cells: HELA in BMLS
    *** source: 21464307-Fig-5c
  *** Akt1[Ab] infraction(S100)[WB] is detectable
    *** cells: HELA in BMS
    *** source: 21464307-Fig-5c
  *** Akt1[Ab] infraction(S100)[WB] is detectable
    *** cells: MDCK2 in BMS
    *** source: 21464307-Fig-5c
  *** Akt1[Ab] prot-exp[WB] is detectable
    *** cells: mESCs in BMS
    *** does not req: Pdpk1 [KO]
    *** source: 11078882-Fig-1
  *** Akt1[Ab]IP IVKA(Gsk3s)[32P-ATP] is detectable
    *** cells: COS1 in BMLS
    *** inhibited by: xPtk6 [addition]
    *** inhibited by: xPtk6(Y447F) [substitution]
    *** unaffected by: xPtk6(K219M)"KD" [addition]
    *** source: 15539407-Fig-5b
  *** Akt1[Ab]IP IVKA(HistH2B)[32P-ATP] is increased itpo xPik3c?(mnr)"CAAX"
    *** cells: COS7 in BMS
    *** inhibited by: xPik3ca(CAAX/R916P) [substitution]
    *** source: 8999998-Fig-3a
  *** Akt1[Ab]IP IVKA(HistH2B)[32P-ATP] is increased itpo xRac1(G12V)
    *** cells: NK92 in BMS "IL2 deprived"
    *** source: 12393431-Fig-5d
  *** rAkt1[GST] boundby[WB] Plcg1[Ab] is detectable
    *** cells: none
    *** IPfrom: COS7 in BMLS "treated with Egf for 15 min"
    *** comment: reqs Egf treatment [omission]
    *** source: 16525023-Fig-2d
  *** xAkt1[GST]IP phos(T308)[phosAb] is increased itpo xSmad2
    *** cells: HEK293T<xPdpk1> in BMS
    *** source: 17327236-Fig-4b
  *** xAkt1[GST]IP phos(T308)[phosAb] is increased itpo xSmad3
    *** cells: HEK293T<xPdpk1> in BMS
    *** source: 17327236-Fig-4b
  *** xAkt1[GST]IP phos(T308)[phosAb] is increased itpo xSmad7
    *** cells: HEK293T<xPdpk1> in BMS
    *** source: 17327236-Fig-4b
  *** Akt1[phosAb] phos(S473)[phosAb] is decreased itpo xPten
    *** cells: JURKAT<Pten~null> in BMS
    *** source: 16603397-Fig-S3
  *** Akt1[phosAb] phos(S473)[phosAb] is decreased itpo xRasa1(456-1047)"Cterm"
    *** cells: HELA in BMS
    *** source: 11847220-Fig-4b
  *** xAkt1[phosAb] phos(S473)[phosAb] is decreased itpo xRheb
    *** cells: HEK293<xAkt1> in BMS
    *** source: 12820960-Fig-3c
  *** Akt1[phosAb] phos(S473)[phosAb] is detectable
    *** cells: 3T3L1 in BMS
    *** reqs: Pras40 [RNAi]
    *** source: 17277771-Fig-2a
  *** Akt1[phosAb] phos(S473)[phosAb] is detectable
    *** cells: 786O in BMLS
    *** inhibited by: xPld1(K898R)"CIA" + xPld2(K758R)"CIA" [addition]
    *** comment: inhibition is reversed by addition of PA for 3 hr
    *** source: 19114562-Fig-2e
  *** Akt1[phosAb] phos(S473)[phosAb] is detectable
    *** cells: 786O in BMS
    *** inhibited by: xPld1(K898R)"CIA" [addition]
    *** inhibited by: xPld2(K758R)"CIA" [addition]
    *** source: 19114562-Fig-2d
  *** Akt1[phosAb] phos(S473)[phosAb] is detectable
    *** cells: HEK293 in BMS "Leucine deprived"
    *** does not req: Mtor [RNAi]
    *** source: 12150925-Fig-5a
  *** Akt1[phosAb] phos(S473)[phosAb] is detectable
    *** cells: HEK293<xSgk1> in BMS
    *** inhibited by: PI103 [pretreatment]
    *** unaffected by: Rapamycin [pretreatment]
    *** source: 18925875-Fig-5a
  *** Akt1[phosAb] phos(S473)[phosAb] is detectable
    *** cells: HELA in BMS
    *** inhibited by: LY294002 [pretreatment]
    *** inhibited by: Wortmannin [pretreatment]
    *** partially inhibited by: Rapamycin [pretreatment]
    *** source: 21464307-Fig-5b
  *** Akt1[phosAb] phos(S473)[phosAb] is detectable
    *** cells: HELA in BMS
    *** reqs: Rictor [RNAi]
    *** source: 19446321-Fig-4g
  *** Akt1[phosAb] phos(S473)[phosAb] is detectable
    *** cells: HELA<xSgk1> in BMS
    *** inhibited by: PI103 [pretreatment]
    *** unaffected by: Rapamycin [pretreatment]
    *** source: 18925875-Fig-5c
  *** Akt1[phosAb] phos(S473)[phosAb] is detectable
    *** cells: HELA<xTbk1> in BMS
    *** partially inhibited by: xTbk1(mnr)"KD" [substitution]
    *** source: 21464307-Fig-S5a
  *** Akt1[phosAb] phos(S473)[phosAb] is detectable
    *** cells: HELA<xTbk1> in BMS
    *** partially reqs: Mtor [RNAi]
    *** partially reqs: Rictor [RNAi]
    *** source: 21464307-Fig-S5a
  *** Akt1[phosAb] phos(S473)[phosAb] is detectable
    *** cells: HEPG2 in BMLS "plated on collagen"
    *** unaffected by: Gefitinib [cotreatment]
    *** unaffected by: PD325901 [cotreatment]
    *** inhibited by: BMS345541 [cotreatment]
    *** unaffected by: PHA818637 [cotreatment]
    *** inhibited by: ZSTK474 [cotreatment]
    *** source: 19953085-Fig-S1
  *** Akt1[phosAb] phos(S473)[phosAb] is detectable
    *** cells: HEPG2 in BMS
    *** reqs: Pras40 [RNAi]
    *** source: 17277771-Fig-2a
  *** Akt1[phosAb] phos(S473)[phosAb] is detectable
    *** cells: MCF7<xSgk1> in BMS
    *** inhibited by: PI103 [pretreatment]
    *** unaffected by: Rapamycin [pretreatment]
    *** source: 18925875-Fig-5b
  *** Akt1[phosAb] phos(S473)[phosAb] is detectable
    *** cells: OCIMY5 in BMS
    *** reqs: Deptor [RNAi]
    *** source: 19446321-Fig-6e
  *** Akt1[phosAb] phos(S473)[phosAb] is detectable
    *** cells: PC12<xGab1> in BMLS
    *** unaffected by: PD98059 [addition]
    *** inhibited by: LY294002 [addition]
    *** source: 10601297-Fig-9c
  *** Akt1[phosAb] phos(S473)[phosAb] is detectable
    *** cells: RPMI8226 in BMS
    *** does not req: Raptor [RNAi]
    *** source: 19446321-Fig-S9
  *** Akt1[phosAb] phos(S473)[phosAb] is detectable
    *** cells: RPMI8226 in BMS
    *** reqs: Deptor [RNAi]
    *** comment: requirement for Deptor can be overcome itao Raptor
    *** source: 19446321-Fig-S9
  *** Akt1[phosAb] phos(S473)[phosAb] is detectable
    *** cells: RPMI8226 in BMS
    *** reqs: Deptor [RNAi]
    *** source: 19446321-Fig-6e
  *** Akt1[phosAb] phos(S473)[phosAb] is detectable
    *** cells: RPMI8226 in BMS
    *** reqs: Maf [RNAi]
    *** source: 19446321-Fig-6j
  *** xAkt1[phosAb] phos(S473)[phosAb] is detectable-but unchanged itpo xBnip3
    *** cells: HEK293<xS6k1> in BMS
    *** source: 17928295-Fig-2d
  *** xAkt1[phosAb] phos(S473)[phosAb] is detectable-but unchanged itpo xRagA
    *** cells: HEK293<xEif4ebp1> in BMS
    *** unaffected by: xRagC [addition]
    *** source: 18604198-Fig-2c
  *** xAkt1[phosAb] phos(S473)[phosAb] is detectable-but unchanged itpo xRagA(Q66L)
    *** cells: HEK293<xEif4ebp1> in BMS
    *** unaffected by: xRagA(Q120L) [addition]
    *** source: 18604198-Fig-2c
  *** xAkt1[phosAb] phos(S473)[phosAb] is detectable-but unchanged itpo xRagA(T21N)
    *** cells: HEK293<xEif4ebp1> in BMS
    *** unaffected by: xRagC(S75N) [addition]
    *** source: 18604198-Fig-2c
  *** xAkt1[phosAb] phos(S473)[phosAb] is detectable-but unchanged itpo xRagC
    *** cells: HEK293<xEif4ebp1> in BMS
    *** unaffected by: xRagA [addition]
    *** source: 18604198-Fig-2c
  *** xAkt1[phosAb] phos(S473)[phosAb] is detectable-but unchanged itpo xRagC(Q120L)
    *** cells: HEK293<xEif4ebp1> in BMS
    *** unaffected by: xRagA(Q120L) [addition]
    *** source: 18604198-Fig-2c
  *** xAkt1[phosAb] phos(S473)[phosAb] is detectable-but unchanged itpo xRagC(S75N)
    *** cells: HEK293<xEif4ebp1> in BMS
    *** unaffected by: xRagA(T21N) [addition]
    *** source: 18604198-Fig-2c
  *** Akt1[phosAb] phos(S473)[phosAb] is increased irt anti-Itgav-adherence (60 min)
    *** cells: ECV304 in BMLS
    *** comment: no controls for total Akt1 were performed
    *** enhanced by: Egf (tnr) [stim]
    *** source: 18844239-Fig-2c
  *** Akt1[phosAb] phos(S473)[phosAb] is increased irt anti-Itgb1-adherence (60 min)
    *** cells: ECV304 in BMLS
    *** comment: no controls for total Akt1 were performed
    *** enhanced by: Egf (tnr) [stim]
    *** source: 18844239-Fig-2c
  *** Akt1[phosAb] phos(S473)[phosAb] is increased itao Cav1 [RNAi]
    *** cells: bAECs in BMLS
    *** source: 15292187(D)
  *** Akt1[phosAb] phos(S473)[phosAb] is increased itao Deptor [RNAi]
    *** cells: HELA in BMS
    *** source: 19446321-Fig-2c
  *** Akt1[phosAb] phos(S473)[phosAb] is increased itao Deptor [RNAi]
    *** cells: mEFs<Tp53~null> in BMS
    *** source: 19446321-Fig-2c
  *** Akt1[phosAb] phos(S473)[phosAb] is increased itao Pten [RNAi]
    *** cells: DLD1 in BMS
    *** source: 16603397-Fig-S3
  *** Akt1[phosAb] phos(S473)[phosAb] is increased itao Raptor [RNAi]
    *** cells: HELA in BMS
    *** source: 19446321-Fig-4g
  *** Akt1[phosAb] phos(S473)[phosAb] is increased itao Tsc2 [RNAi]
    *** cells: WM35 in BMS
    *** source: 18570873-Fig-7e
  *** xAkt1[phosAb] phos(S473)[phosAb] is increased itpo (xGab1 + xFgfR1)
    *** cells: HEK293 in BMS
    *** inhibited by: xGab1(Y448F/Y473F/Y590F) [substitution]
    *** source: 11353842-Fig-6c
  *** xAkt1[phosAb] phos(S473)[phosAb] is increased itpo (xGab1 + xFgfR1)
    *** cells: HEK293 in BMS
    *** reqs: xGab1 [omission]
    *** reqs: xFgfR1 [omission]
    *** source: 11353842-Fig-6b
  *** Akt1[phosAb] phos(S473)[phosAb] is increased itpo xGab1
    *** cells: PC12 in BMLS
    *** source: 10601297-Fig-4a
  *** Akt1[phosAb] phos(S473)[phosAb] is increased itpo xGnai3(Q204L)"CA"
    *** cells: mEFs<Gnai1~null><Gnai3~null> in BMLS
    *** source: 19401591-Fig-3d
  *** Akt1[phosAb] phos(S473)[phosAb] is increased itpo xHras(Q61L)"CA"
    *** cells: PC6 in BMLS
    *** source: 15632082-Fig-1c
  *** Akt1[phosAb] phos(S473)[phosAb] is increased itpo xMras(H81L)"CA"
    *** cells: MCF7 in BMS
    *** unaffected by: xShoc2 [addition]
    *** inhibited by: xMras(H81L/D48A) [substitution]
    *** source: 16630891-Fig-2a
  *** Akt1[phosAb] phos(S473)[phosAb] is increased itpo xMras(H81L)"CA"
    *** cells: PAE in BMS
    *** unaffected by: xShoc2 [addition]
    *** inhibited by: xMras(H81L/D48A) [substitution]
    *** source: 16630891-Fig-2a
  *** Akt1[phosAb] phos(S473)[phosAb] is increased itpo xPik3c?(mnr)"CA"
    *** cells: hNKCs in BMS "IL2-deprived"
    *** source: 12393431-Fig-5b
  *** Akt1[phosAb] phos(S473)[phosAb] is increased itpo xPik3c?(mnr)"CA"
    *** cells: NK92 in BMS "IL2 deprived"
    *** source: 12393431-Fig-4a
  *** Akt1[phosAb] phos(S473)[phosAb] is increased itpo xRac1(G12V)
    *** cells: NK92 in BMS "IL2 deprived"
    *** source: 12393431-Fig-5b
  *** Akt1[phosAb] phos(S473)[phosAb] is increased itpo xRac1(G12V)
    *** cells: NK92 in BMS "IL2 deprived"
    *** source: 12393431-Fig-5c
  *** Akt1[phosAb] phos(S473)[phosAb] is increased itpo xRac1(Q61L)"CA"
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-5b
  *** Akt1[phosAb] phos(S473)[phosAb] is increased itpo xRalGds
    *** cells: NIH3T3 in BMS
    *** partially inhibited by: xRalGds(mnr)"del-Nterm" [substitution]
    *** source: 18285454-Fig-8a
  *** Akt1[phosAb] phos(S473)[phosAb] is increased itpo xRasa1((1-445)/D157A)"Casp-resistant"
    *** cells: HELA in BMS
    *** source: 11847220-Fig-4b
  *** rAkt1[phosAb] phos(S473)[phosAb] is unchanged by (rPdpk1 + rFreud1 + PIP3)
    *** cells: none
    *** unaffected by: rFreud1 [omission]
    *** unaffected by: PIP3 [omission]
    *** source: 18662999-Fig-5g
  *** rAkt1[phosAb] phos(S473)[phosAb] is unchanged by Ikk1[Ab]IP
    *** cells: none
    *** IPfrom: HELA in BMS
    *** source: 21464307-Fig-3b
  *** rAkt1[phosAb] phos(S473)[phosAb] is unchanged by xIkk1[tAb]IP
    *** cells: none
    *** IPfrom: HEK293<xIkk1> in BMS
    *** source: 21464307-Fig-3a
  *** Akt1[phosAb] phos(S473)[phosAb] is unchanged itpo (xPdpk1 + xPkcz)
    *** cells: HEK293E<xS6k1> in BMLS
    *** unaffected by: xS6k1(mnr)"F5adCT" [substitution]
    *** source: 12906785-Fig-4
  *** xAkt1[phosAb] phos(S473)[phosAb] is unchanged itpo (xTsc1 + xTsc2)
    *** cells: HEK293 in BMS
    *** source: 12172553-Fig-1d
  *** xAkt1[phosAb] phos(S473)[phosAb] is unchanged itpo (xTsc1 + xTsc2)
    *** cells: HEK293 in BMS
    *** source: 12172553-Fig-2b
  *** xAkt1[phosAb] phos(S473)[phosAb] is unchanged itpo xFrs2
    *** cells: HEK293 in BMS
    *** source: 11353842-Fig-6b
  *** Akt1[phosAb] phos(S473)[phosAb] is unchanged itpo xHras(G12V)
    *** cells: HEK293T<xS6k1> in BMS
    *** enhanced by: AA-deprivation [pretreatment]
    *** source: 15854902-Fig-S1
  *** Akt1[phosAb] phos(S473)[phosAb] is unchanged itpo xMras(H81L)"CA"
    *** cells: BT549 in BMS
    *** unaffected by: xShoc2 [addition]
    *** inhibited by: xMras(H81L/D48A) [substitution]
    *** comment: Akt1-phos(S473) is already detectable in untreated BT549
    *** source: 16630891-Fig-2a
  *** Akt1[phosAb] phos(S473)[phosAb] is unchanged itpo xRap1b(G12V)
    *** cells: HEK293T<xS6k1> in BMS
    *** unaffected by: AA-deprivation [pretreatment]
    *** source: 15854902-Fig-S1
  *** xAkt1[phosAb] phos(S473)[phosAb] is unchanged itpo xRheb
    *** cells: HEK293<xAkt1> in BMS
    *** source: 12869586-Fig-4c
  *** Akt1[phosAb] phos(S473)[phosAb] is unchanged itpo xRheb
    *** cells: HEK293E in BMS
    *** source: 12906785-Fig-1b
  *** xAkt1[phosAb] phos(S473)[phosAb] is unchanged itpo xRheb
    *** cells: HEK293E<xAkt1> in BMLS
    *** source: 12906785-Fig-1b
  *** Akt1[phosAb] phos(S473)[phosAb] is unchanged itpo xRheb
    *** cells: HEK293E<xEif4ebp1> in BMLS
    *** source: 12906785-Fig-2a
  *** Akt1[phosAb] phos(S473)[phosAb] is unchanged itpo xRheb
    *** cells: HEK293E<xS6k1> in BMLS
    *** unaffected by: xS6k1(mnr)"F5adCT" [substitution]
    *** source: 12906785-Fig-4
  *** Akt1[phosAb] phos(S473)[phosAb] is unchanged itpo xRheb
    *** cells: HEK293E<xS6k1> in BSS "containing Glucose and AminoAcids"
    *** unaffected by: Rapamycin [pretreatment]
    *** unaffected by: Wortmannin [pretreatment]
    *** source: 12906785-Fig-3
  *** Akt1[phosAb] phos(S473)[phosAb] is unchanged itpo xRheb
    *** cells: HEK293E<xS6k1> in BSS "containing Glucose"
    *** unaffected by: Rapamycin [pretreatment]
    *** unaffected by: Wortmannin [pretreatment]
    *** source: 12906785-Fig-3
  *** Akt1[phosAb] phos(S473)[phosAb] is unchanged itpo xRheb
    *** cells: HEK293T<xS6k1> in BMS
    *** unaffected by: AA-deprivation [pretreatment]
    *** source: 15854902-Fig-S1
  *** Akt1[phosAb] phos(S473)[phosAb] is unchanged itpo xRhog(Q61L)"CA"
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-5b
  *** Akt1[phosAb] phos(S473)[phosAb] is unchanged itpo xRin1(Q78L)
    *** cells: PC6 in BMLS
    *** source: 16157584-Fig-1d
  *** Akt1[phosAb] phos(S473)[phosAb] is unchanged itpo xRit1
    *** cells: PC6 in BMLS
    *** unaffected by: xRit1(Q79L)"CA" [substitution]
    *** source: 15632082-Fig-1c
  *** Akt1[phosAb] phos(S473/T308)[phosAb] is increased itpo xHras(G12R)"CA"
    *** cells: NIH3T3 in BMLS
    *** source: 11340168-Fig-1b
  *** Akt1[phosAb] phos(S473/T308)[phosAb] is increased itpo xHras(G12V)"CA"
    *** cells: NIH3T3 in BMLS
    *** source: 11340168-Fig-2a
  *** Akt1[phosAb] phos(S473/T308)[phosAb] is increased itpo xRras2(G23V)"CA"
    *** cells: NIH3T3 in BMLS
    *** inhibited by: xRras2(G23V/E46S) [substitution]
    *** source: 11340168-Fig-2a
  *** Akt1[phosAb] phos(S473/T308)[phosAb] is increased itpo xRras2(G23V)"CA"
    *** cells: NIH3T3 in BMLS
    *** inhibited by: xRras2(G23V/E48G) [substitution]
    *** inhibited by: xRras2(G23V/E46S) [substitution]
    *** unaffected by: xRras2(G23V/Y51C) [substitution]
    *** source: 11340168-Fig-1b
  *** Akt1[phosAb] phos(S473/T308)[phosAb] is increased itpo xRras2(G23V)"CA"
    *** cells: NIH3T3 in BMLS
    *** inhibited by: xRras2(G23V/E48G) [substitution]
    *** unaffected by: xRras2(G23V/Y51C) [substitution]
    *** source: 11340168-Fig-2b
  *** Akt1[phosAb] phos(S473/T308)[phosAb] is increased itpo xRras2(G23V)"CA"
    *** cells: NIH3T3 in BMLS
    *** unaffected by: U0126 [addition]
    *** inhibited by: LY294002 [addition]
    *** source: 11340168-Fig-1b
  *** Akt1[phosAb] phos(S473/T308)[phosAb] is unchanged itpo xRras(mnr)"CA"
    *** cells: NIH3T3 in BMLS
    *** source: 11340168-Fig-2c
  *** Akt1[phosAb] phos(sitenr)[phosAb] is increased itao Pten [KO]
    *** cells: mEFs in BMS
    *** source: 14517213-Fig-4a
  *** Akt1[phosAb] phos(sitenr)[phosAb] is increased itao Rin1 [RNAi]
    *** cells: HEPG2 in BMS
    *** source: 16457816-Fig-5a
  *** Akt1[phosAb] phos(sitenr)[phosAb] is increased itao Rin3 [RNAi]
    *** cells: HEPG2 in BMS
    *** source: 16457816-Fig-5a
  *** Akt1[phosAb] phos(sitenr)[phosAb] is increased itpo xHras(Q61L)"CA"
    *** cells: NIH3T3 in BMS
    *** inhibited by: Wortmannin [addition]
    *** source: 11788587-Fig-6
  *** Akt1[phosAb] phos(sitenr)[phosAb] is increased itpo xRras2(Q72L)"CA"
    *** cells: NIH3T3 in BMS
    *** inhibited by: Wortmannin [addition]
    *** source: 11788587-Fig-6
  *** Akt1[phosAb] phos(sitenr)[phosAb] is unchanged itao Rin2 [RNAi]
    *** cells: HEPG2 in BMS
    *** source: 16457816-Fig-5a
  *** Akt1[phosAb] phos(sitenr)[phosAb] is unchanged itpo xMek1
    *** cells: mEFs in BMS
    *** source: 16698790-Fig-6b
  *** Akt1[phosAb] phos(sitenr)[phosAb] is unchanged itpo xPak1(T423E)"CA"
    *** cells: mEFs in BMS
    *** source: 16698790-Fig-6b
  *** Akt1[phosAb] phos(sitenr)[phosAb] is unchanged itpo xRock1
    *** cells: mEFs in BMS
    *** source: 16698790-Fig-6b
  *** xAkt1[phosAb] phos(T308)[phosAb] is detectable
    *** cells: COS7<xAkt1><xPdpk1> in BMLS "treated with Serum for 10 min"
    *** inhibited by: xPdpk1(S241A) [substitution]
    *** unaffected by: xPdpk1(R238E) [substitution]
    *** enhanced by: xPdpk1(V243P) [substitution]
    *** source: 12177059-Fig-4a
  *** Akt1[phosAb] phos(T308)[phosAb] is detectable
    *** cells: HELA in BMS
    *** partially inhibited by: LY294002 [pretreatment]
    *** unaffected by: Wortmannin [pretreatment]
    *** unaffected by: Rapamycin [pretreatment]
    *** source: 21464307-Fig-5b
  *** Akt1[phosAb] phos(T308)[phosAb] is detectable
    *** cells: HELA<xTbk1> in BMS
    *** does not req: Mtor [RNAi]
    *** does not req: Rictor [RNAi]
    *** source: 21464307-Fig-S5a
  *** Akt1[phosAb] phos(T308)[phosAb] is detectable
    *** cells: HELA<xTbk1> in BMS
    *** inhibited by: xTbk1(mnr)"KD" [substitution]
    *** source: 21464307-Fig-S5a
  *** Akt1[phosAb] phos(T308)[phosAb] is detectable
    *** cells: OCIMY5 in BMS
    *** reqs: Deptor [RNAi]
    *** source: 19446321-Fig-6e
  *** Akt1[phosAb] phos(T308)[phosAb] is detectable
    *** cells: RPMI8226 in BMS
    *** does not req: Raptor [RNAi]
    *** source: 19446321-Fig-S9
  *** Akt1[phosAb] phos(T308)[phosAb] is detectable
    *** cells: RPMI8226 in BMS
    *** reqs: Deptor [RNAi]
    *** comment: requirement for Deptor can be overcome itao Raptor
    *** source: 19446321-Fig-S9
  *** Akt1[phosAb] phos(T308)[phosAb] is detectable
    *** cells: RPMI8226 in BMS
    *** reqs: Deptor [RNAi]
    *** source: 19446321-Fig-6e
  *** Akt1[phosAb] phos(T308)[phosAb] is detectable
    *** cells: RPMI8226 in BMS
    *** reqs: Maf [RNAi]
    *** source: 19446321-Fig-6j
  *** Akt1[phosAb] phos(T308)[phosAb] is increased itao Raptor [RNAi]
    *** cells: A549 in BMS
    *** source: 15718470-Fig-2a
  *** Akt1[phosAb] phos(T308)[phosAb] is increased itao Raptor [RNAi]
    *** cells: HT29 in BMS
    *** source: 15718470-Fig-2a
  *** xAkt1[phosAb] phos(T308)[phosAb] is increased itpo (xTsc1 + xTsc2)
    *** cells: HEK293 in BMS
    *** source: 12172553-Fig-1d
  *** Akt1[phosAb] phos(T308)[phosAb] is increased itpo xHras(mnr)"CA"
    *** cells: 32D<xCsf1R> in BMLS
    *** times: 0 5+ 10+ 30 min
    *** partially inhibited by: xCsf1R(del(678-747))"Pik3r-binding-mut" [substitution]
    *** source: 10958675-Fig-7b
  *** Akt1[phosAb] phos(T308)[phosAb] is increased itpo xRalGds
    *** cells: NIH3T3 in BMS
    *** partially inhibited by: xRalGds(mnr)"del-Nterm" [substitution]
    *** source: 18285454-Fig-8a
  *** rAkt1[phosAb] phos(T308)[phosAb] is unchanged by Ikk1[Ab]IP
    *** cells: none
    *** IPfrom: HELA in BMS
    *** source: 21464307-Fig-3b
  *** rAkt1[phosAb] phos(T308)[phosAb] is unchanged by xIkk1[tAb]IP
    *** cells: none
    *** IPfrom: HEK293<xIkk1> in BMS
    *** source: 21464307-Fig-3a
  *** Akt1[phosAb] phos(T309)[phosAb] is detectable
    *** cells: 786O in BMS
    *** inhibited by: xPld1(K898R)"CIA" [addition]
    *** inhibited by: xPld2(K758R)"CIA" [addition]
    *** source: 19114562-Fig-2d
  *** xAkt1[tAb] copptby[WB] Plcg1[Ab] is detectable
    *** cells: COS7<xAkt1> in BMLS "treated with Egf for 30 min"
    *** partially inhibited by: xAkt1(P424A) [substitution]
    *** partially inhibited by: xAkt1(P467A) [substitution]
    *** inhibited by: xAkt1(P424A/P467A) [substitution]
    *** source: 16525023-Fig-4a
  *** xAkt1[tAb] copptby[WB] xFreud1[tAb] is detectable
    *** cells: HEK293T<xFreud1><xAkt1> in BMS
    *** unaffected by: xAkt1(K179A) [substitution]
    *** unaffected by: xAkt1(K179A/S473A) [substitution]
    *** unaffected by: xAkt1(K179A/T308A/S473A) [substitution]
    *** source: 18662999-Fig-4d
  *** xAkt1[tAb] copptby[WB] xTpl2[tAb] is detectable
    *** cells: HEK293T<xTpl2><xAkt1> in BMS
    *** source: 12138205-Fig-2b
  *** xAkt1[tAb]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: HEK293T<xAkt1> in BMS
    *** enhanced by: xTpl2(del(424-468)) [addition]
    *** enhanced by: xTpl2(del(397-468)) [addition]
    *** comment: coppt xTpl2 and xTpl2(del(424-468)) are also phosed
    *** comment: coppt xTpl2(del(397-468)) is not phosed
    *** source: 12138205-Fig-3a
  *** xAkt1[tAb]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: HEK293T<xAkt1> in BMS
    *** unaffected by: xTpl2(del(424-468)) [addition]
    *** unaffected by: xTpl2(del(397-468)) [addition]
    *** comment: coppt xTpl2 and xTpl2(del(424-468)) are also phosed
    *** comment: coppt xTpl2(del(397-468)) is not phosed
    *** comment: coppt xTpl2(S400A) and xTpl2(S413A) are also phosed
    *** comment: coppt xTpl2(S400A/S413A) is not phosed
    *** source: 12138205-Fig-4
  *** xAkt1[tAb]IP IVKA(HistH2B)[32P-ATP] is increased itpo xHras(G12V)"CA"
    *** cells: NIH3T3<xInsR> in BMS
    *** inhibited by: LY294002 [addition]
    *** inhibited by: xAkt1(R25C)"PH-domain-mut" [substitution]
    *** source: 8999998-Fig-3b
  *** xAkt1[tAb]IP IVKA(HistH2B)[32P-ATP] is increased itpo xMras(Q71L)"CA"
    *** cells: NIH3T3 in BMLS
    *** inhibited by: LY294002 [addition]
    *** inhibited by: Wortmannin [addition]
    *** source: 10803462-Fig-3,4
  *** xAkt1[tAb]IP IVKA(HistH2B)[32P-ATP] is increased itpo xPik3c?(mnr)"CAAX"
    *** cells: COS7<xAkt1> in BMLS
    *** source: 10330169-Fig-3d
  *** xAkt1[tAb]IP IVKA(HistH2B)[32P-ATP] is increased itpo xPik3c?(mnr)"CAAX"
    *** cells: NIH3T3<xInsR> in BMS
    *** inhibited by: LY294002 [addition]
    *** inhibited by: xAkt1(R25C)"PH-domain-mut" [substitution]
    *** source: 8999998-Fig-3b
  *** xAkt1[tAb]IP IVKA(HistH2B)[32P-ATP] is increased itpo xRras(G38V)"CA"
    *** cells: NIH3T3<xInsR> in BMS
    *** inhibited by: LY294002 [addition]
    *** inhibited by: xAkt1(R25C)"PH-domain-mut" [substitution]
    *** source: 8999998-Fig-3b
  *** xAkt1[tAb]IP IVKA(HistH2B)[32P-ATP] is increased itpo xSrc(mnr)"vSrc"
    *** cells: COS7<xAkt1> in BMLS
    *** source: 10330169-Fig-3d
  *** xAkt1[tAb]IP IVKA(HistH2B)[32P-ATP] is increased itpo xSrc(mnr)"vSrc"
    *** cells: NIH3T3<xInsR> in BMS
    *** inhibited by: LY294002 [addition]
    *** inhibited by: xAkt1(R25C)"PH-domain-mut" [substitution]
    *** source: 8999998-Fig-3b
  *** xAkt1[tAb]IP IVKA(HistH2B)[32P-ATP] is unchanged itpo xHras(G12R)"CA"
    *** cells: NIH3T3 in BMLS
    *** source: 10803462-Fig-3
  *** xAkt1[tAb]IP IVKA(HistH2B)[32P-ATP] is unchanged itpo xRac1(G12V)"CA"
    *** cells: NIH3T3<xInsR> in BMS
    *** inhibited by: xAkt1(R25C)"PH-domain-mut" [substitution]
    *** source: 8999998-Fig-3b
  *** xAkt1[tAb]IP IVKA(HistH2B)[32P-ATP] is unchanged itpo xRaf1(mnr)"CAAX"
    *** cells: NIH3T3<xInsR> in BMS
    *** source: 8999998-Fig-3b
  *** xAkt1[tAb]IP IVKA(HistH3)[32P-ATP] is unchanged itpo xCdc42(G12V)"CA"
    *** cells: NIH3T3 in BMLS
    *** source: 8653792-Fig-5d
  *** xAkt1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xKras(G12V)"CA"
    *** cells: HEK293 in BMLS
    *** unaffected by: xShoc2 [addition]
    *** source: 10783161-Fig-2e
  *** xAkt1[tAb]IP IVLKA(PtdIns)[TLC] is increased itpo xMras(Q71L)"CA"
    *** cells: NIH3T3 in BMLS
    *** source: 10803462-Fig-4
  *** xAkt1[tAb]IP phos(S473)[phosAb] is increased itpo xDeptor
    *** cells: HELA<xAkt1> in BMS
    *** inhibited by: xDeptor(dig)"13ST/A" [substitution]
    *** source: 19446321-Fig-5c
  *** xAkt1[tAb]IP phos(S473)[phosAb] is increased itpo xDeptor
    *** cells: mEFs<Tp53~null><xAkt1> in BMS
    *** source: 19446321-Fig-S4
  *** xAkt1[tAb]IP phos(S473)[phosAb] is increased itpo xPras40
    *** cells: HELA<xAkt1> in BMS
    *** source: 19446321-Fig-5c
  *** xAkt1[tAb]IP phos(sitenr)[phosAb] is increased itpo xMras(Q71L)"CA"
    *** cells: PC12 in BMS
    *** source: 10803462-Fig-6
  *** xAkt1[tAb]IP phos(sitenr)[phosAb] is unchanged itpo xHras(G12R)"CA"
    *** cells: PC12 in BMS
    *** source: 10803462-Fig-6
  *** xAkt1[tAb]IP phos(T308)[phosAb] is detectable
    *** cells: SYF<Src~null><Yes1~null><Fyn~null><xAkt1> in BMLS
    *** inhibited by: xAkt1(Y315F/T326F) [substitution]
    *** source: 20606012-Fig-7d
  *** xAkt1[tAb]IP phos(T308)[phosAb] is increased itpo xDeptor
    *** cells: HELA<xAkt1> in BMS
    *** unaffected by: xDeptor(dig)"13ST/A" [substitution]
    *** source: 19446321-Fig-5c
  *** xAkt1[tAb]IP phos(T308)[phosAb] is increased itpo xDeptor
    *** cells: mEFs<Tp53~null><xAkt1> in BMS
    *** source: 19446321-Fig-S4
  *** xAkt1[tAb]IP phos(T308)[phosAb] is increased itpo xPras40
    *** cells: HELA<xAkt1> in BMS
    *** source: 19446321-Fig-5c
  *** xAkt1[tAb]IP phos(T308)[phosAb] is increased itpo xPtk6(Y447F)
    *** cells: SYF<Src~null><Yes1~null><Fyn~null><xAkt1> in BMLS
    *** source: 20606012-Fig-7d
*** Akt2--
  *** xAkt2[tAb] copptby[WB] xJip1[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 12194869(D)
  *** Akts[Ab] snaggedby[WB] rPlcg1(mnr)"SH3"[GST] is detectable
    *** cells: COS7 in BMLS
    *** inhibited by: rPlcg1(mnr)"NSH2" [substitution]
    *** inhibited by: rPlcg1(mnr)"CSH2" [substitution]
    *** inhibited by: rPlcg1(mnr)"NPH" [substitution]
    *** enhanced by: rPlcg1(mnr)"SH2-SH2-SH3" [substitution]
    *** source: 16525023-Fig-3a
  *** rAldoa[MS] cleavage[WB] is increased by rCasp1
    *** cells: none
    *** source: 17959595(D)
  *** rAldoa[MS] cleavage[WB] is unchanged by rCasp3
    *** cells: none
    *** source: 17959595(D)
*** Alox15--
  *** Alox15[Ab] prot-exp[WB] is increased itpo xStat6
    *** cells: BEAS2B in BMS "treated with IL4 for 48 hr"
    *** source: 10657944-Fig-3
*** Ampk--
  *** Ampk[Ab] copptby[WB] xLkb1[tAb] is increased itao Braf(V600E) [RNAi]
    *** cells: SKMEL28 in BMS
    *** source: 19187764-Fig-2a
  *** Ampk[phosAb] phos(T172)[phosAb] is decreased itpo xAkt1(myr)"CA"
    *** cells: mEFs<Tsc2~null> in BMS
    *** source: 16027121-Fig-6c
  *** Ampk[phosAb] phos(T172)[phosAb] is decreased itpo xAkt1(myr)"CA"
    *** cells: RAT1A in BMS
    *** unaffected by: Serum-deprivation [pretreatment]
    *** source: 16027121-Fig-2f
  *** Ampk[phosAb] phos(T172)[phosAb] is detectable
    *** cells: EEF4 in BMS
    *** enhanced by: Rottlerin [addition]
    *** enhanced by: FCCP [addition]
    *** unaffected by: NaN3 [addition]
    *** enhanced by: Oligomycin [addition]
    *** enhanced by: Rotenone [addition]
    *** source: 14651849-Fig-3d
  *** Ampk[phosAb] phos(T172)[phosAb] is detectable
    *** cells: EEF8<Tsc2~null> in BMS
    *** enhanced by: Rottlerin [addition]
    *** enhanced by: FCCP [addition]
    *** unaffected by: NaN3 [addition]
    *** unaffected by: Oligomycin [addition]
    *** enhanced by: Rotenone [addition]
    *** source: 14651849-Fig-3d
  *** Ampk[phosAb] phos(T172)[phosAb] is detectable
    *** cells: mEFs in BMS
    *** reqs: Lkb1 [KO]
    *** source: 18439900-Fig-5c
  *** Ampk[phosAb] phos(T172)[phosAb] is detectable
    *** cells: mHepatocytes in BMS
    *** reqs: Lkb1 [KO]
    *** source: 18439900-Fig-S2
  *** Ampk[phosAb] phos(T172)[phosAb] is increased itao Akt1 and/or Akt2 [DKO]
    *** cells: mEFs in BMLS
    *** source: 16027121-Fig-2d
  *** Ampk[phosAb] phos(T172)[phosAb] is increased itao Tsc2 [KO]
    *** cells: mEFs in BMS
    *** source: 16027121-Fig-6c
  *** Ampk[phosAb] phos(T172)[phosAb] is unchanged itpo xAkt1(myr)"CA"
    *** cells: RAT1A in BMS
    *** source: 16027121-Fig-4a
  *** xAmpka?[Ab] copptby[WB] xLkb1[Ab] is decreased itpo xBraf(V600E)
    *** cells: HELA in BMS
    *** reversed by: U0126 [addition]
    *** source: 19274086-Fig-4d
  *** xAmpka?[tAb] copptby[WB] xLkb1[tAb] is detectable
    *** cells: HEK293T in BMLS
    *** inhibited by: xLkb1(S428A) [substitution]
    *** inhibited by: xLkb1(S428D) [substitution]
    *** unaffected by: xLkb1(mnr)"KD" [substitution]
    *** source: 19274086-Fig-4b
  *** rAmpka1[32P] phos[32P-ATP] is detectable
    *** cells: none
    *** comment: reaction also contains rAmpkb1, rAmpkg1, rPkcz, rLkb1
    *** partially inhibited by: rLkb1(S428A) [substitution]
    *** source: 19414597-Fig-1e
  *** rAmpka1[32P] phos[32P-ATP] is unchanged by rPkcz
    *** cells: none
    *** comment: reaction also contains rAmpkb1 and rAmpkg1
    *** source: 19414597-Fig-1c
  *** Ampka1[Ab] prot-exp[WB] is unchanged itao Pdpk1 [KO]
    *** cells: mESCs in BMLS
    *** source: 10801415-Fig-7b
  *** Ampka1[tAb] copptby[WB] Tak1[tAb] is detectable
    *** cells: THP1 in BMS
    *** enhanced by: Lps (45 min) [stim]
    *** source: 22833096-Fig-2d
  *** xAmpka1[tAb] copptby[WB] xTak1[tAb] is detectable
    *** cells: HEK293<xAmpka1><xTak1> in BMS
    *** enhanced by: Lps (45 min) [stim]
    *** source: 22833096-Fig-2a
  *** xAmpka1[tAb] copptby[WB] xTak1[tAb] is detectable
    *** cells: HEK293<xAmpka1><xTak1> in BMS
    *** inhibited by: xAmpka1(1-312) [substitution]
    *** unaffected by: xAmpka1(1-3392) [substitution]
    *** source: 22833096-Fig-2c
  *** Ampkas[Ab]IP phos[32P-ATP] is increased by rPkcz
    *** cells: none
    *** IPfrom: bAECs in BMS
    *** source: 19414597-Fig-1b
  *** Ampkas[phosAb] phos(LRTSC)[phosAb] is detectable
    *** cells: THP1 in BMS
    *** partially reqs: Tak1 [RNAi]
    *** source: 22833096-Fig-2f
  *** Ampkas[phosAb] phos(S496)[phosAb] is detectable
    *** cells: THP1 in BMS
    *** reqs: Tak1 [RNAi]
    *** source: 22833096-Fig-2f
  *** Ampkas[phosAb] phos(T172)[phosAb] is increased irt Glucose-deprivation (4 hr)
    *** cells: A375 in BMLS
    *** source: 19274086-Fig-3a
  *** Ampkas[phosAb] phos(T172)[phosAb] is increased irt Glucose-deprivation (4 hr)
    *** cells: SKMEL28 in BMLS
    *** repressed by: Braf [RNAi]
    *** comment: SKMEL28 contain Braf(V600E) mutation
    *** source: 19274086-Fig-3d
  *** Ampkas[phosAb] phos(T172)[phosAb] is increased irt U0126 (4 hr)
    *** cells: A375 in BMLS "Low-Glucose"
    *** source: 19274086-Fig-3a
  *** Ampkas[phosAb] phos(T172)[phosAb] is increased irt U0126 (4 hr)
    *** cells: SKMEL28 in BMLS "Low-Glucose"
    *** source: 19274086-Fig-3a
  *** Ampkas[phosAb] phos(T172)[phosAb] is increased itao Braf(V600E) [RNAi]
    *** cells: SKMEL28 in BMS
    *** source: 19187764-Fig-2a
  *** Ampkas[phosAb] phos(T172)[phosAb] is increased itao Erk2 [RNAi]
    *** cells: SKMEL28 in BMS
    *** source: 19187764-Fig-S5
  *** Ampkas[phosAb] phos(T172)[phosAb] is increased itao Mek1 [RNAi]
    *** cells: SKMEL28 in BMS
    *** source: 19187764-Fig-2b
  *** Ampkas[phosAb] phos(T172)[phosAb] is unchanged itpo xDvl2
    *** cells: HEK293<xS6k1> in BMS
    *** source: 16959574-Fig-4b
  *** Ampkas[phosAb] phos(T172)[phosAb] is unchanged itpo xDvl2
    *** cells: HEK293<xS6k1> in BMS "Glucose-deprived"
    *** source: 16959574-Fig-4b
  *** AP1-reporter[Luc] is decreased itpo xJnk1(T183A/Y185F)
    *** cells: NCIH82<xHras(G12V)> in BMLS
    *** source: 10667594-Fig-6a
  *** AP1-reporter[Luc] is detectable
    *** cells: rEFs<xJun> in BMS
    *** enhanced by: xJun(S243F) [substitution]
    *** source: 1846781-Fig-6
  *** AP1-reporter[Luc] is detectable
    *** cells: THP1 in BMS
    *** reqs: Ampka1 [RNAi]
    *** source: 22833096-Fig-3a
  *** AP1-reporter[Luc] is increased itpo (xTab1 + xTak1)
    *** cells: mEFs<Tak1~null> in BMS
    *** reqs: xTak1 [omission]
    *** inhibited by: xTak1(K63R) [substitution]
    *** partially inhibited by: xTak1(T178A) [substitution]
    *** partially inhibited by: xTak1(T184A) [substitution]
    *** inhibited by: xTak1(T178A/T184A) [substitution]
    *** unaffected by: xTak1(T178E) [substitution]
    *** unaffected by: xTak1(T184E) [substitution]
    *** unaffected by: xTak1(T178E/T184E) [substitution]
    *** source: 18617512-Fig-1c
  *** AP1-reporter[Luc] is increased itpo (xTak1 + xTab1)
    *** cells: HELA in BMS
    *** inhibited by: xTak1(T187A) [substitution]
    *** inhibited by: xTak1(K63W)"KD" [substitution]
    *** source: 15590691-Fig-1d
  *** AP1-reporter[Luc] is increased itpo xAmpka1
    *** cells: THP1 in BMS
    *** inhibited by: xAmpka1(D159A)"DN" [substitution]
    *** enhanced by: xAmpka1(T174D)"CA" [substitution]
    *** source: 22833096-Fig-1h
  *** AP1-reporter[Luc] is increased itpo xEts1
    *** cells: MDCK in BMLS
    *** partially inhibited by: xEts1(T38A) [substitution]
    *** source: 11948414-Fig-4b
  *** AP1-reporter[Luc] is increased itpo xHras(G12V)
    *** cells: NCIH82 in BMS
    *** source: 10667594-Fig-5a
  *** AP1-reporter[Luc] is increased itpo xTab1
    *** cells: HEK293T<xTak1> in BMS
    *** unaffected by: xTak1(K34R) [substitution]
    *** unaffected by: xTak1(K52R/K54R) [substitution]
    *** unaffected by: xTak1(K58R) [substitution]
    *** inhibited by: xTak1(K63R) [substitution]
    *** unaffected by: xTak1(K72R) [substitution]
    *** unaffected by: xTak1(K91R) [substitution]
    *** unaffected by: xTak1(K150R) [substitution]
    *** inhibited by: xTak1(K158R) [substitution]
    *** unaffected by: xTak1(K172R) [substitution]
    *** unaffected by: xTak1(K190R) [substitution]
    *** unaffected by: xTak1(K209R) [substitution]
    *** unaffected by: xTak1(K227R) [substitution]
    *** unaffected by: xTak1(K253R) [substitution]
    *** unaffected by: xTak1(K257R) [substitution]
    *** unaffected by: xTak1(K269R) [substitution]
    *** unaffected by: xTak1(K282R) [substitution]
    *** source: 20038579-Fig-3f
  *** AP1-reporter[Luc] is increased itpo xTak1
    *** cells: mEFs<Tak1~null><xTab1> in BMS
    *** inhibited by: xTak1(T178A) [substitution]
    *** inhibited by: xTak1(T184A) [substitution]
    *** inhibited by: xTak1(T178A/T184A) [substitution]
    *** unaffected by: xTak1(T178E/T184E) [substitution]
    *** source: 18617512-Fig-3d
  *** AP1-reporter[Luc] is increased itpo xTbp
    *** cells: HUH7 in BMS
    *** source: 17074809-Fig-6c
  *** AP1-reporter[Luc] is increased itpo xTbp
    *** cells: mEFs in BMS
    *** source: 17074809-Fig-6c
  *** AP1-reporter[Luc] is increased itpo xTpl2
    *** cells: JURKATT<Pten~null> in BMS
    *** unaffected by: xTpl2(del(424-468)) [substitution]
    *** enhanced by: xTpl2(del(397-468)) [substitution]
    *** source: 12138205-Fig-3c
  *** AP1-reporter[Luc] is increased itpo xTpl2
    *** cells: JURKATT<Pten~null> in BMS
    *** unaffected by: xTpl2(mnr)"delC" [substitution]
    *** enhanced by: xTpl2(mnr)"M30" [substitution]
    *** inhibited by: xTpl2(mnr)"Q104" [substitution]
    *** source: 12138205-Fig-2c
  *** AP1-reporter[Luc] is increased itpo xTpl2
    *** cells: JURKATT<Pten~null> in BMS
    *** unaffected by: xTpl2(S400A) [substitution]
    *** unaffected by: xTpl2(S413A) [substitution]
    *** unaffected by: xTpl2(S400A/S413A) [substitution]
    *** source: 12138205-Fig-5a
*** Apaf1--
  *** xApaf1[tAb] copptby[WB] xNod1[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 10329646(D)
*** Apbb1ip--
  *** xApbb1ip(1-261)[tAb] copptby[WB] xHras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xHras(G12V/D38A) [substitution]
    *** inhibited by: xHras(G12V/T35S) [substitution]
    *** inhibited by: xHras(G12V/E37G) [substitution]
    *** inhibited by: xHras(G12V/Y40C) [substitution]
    *** inhibited by: xHras(G12V/D38E) [substitution]
    *** source: 15143186-Fig-6
  *** xApbb1ip(1-261)[tAb] copptby[WB] xKras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xApbb1ip(1-261)[tAb] copptby[WB] xMras(Q71L)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xApbb1ip(1-261)[tAb] copptby[WB] xNras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xApbb1ip(1-261)[tAb] copptby[WB] xRap1a(G12V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xApbb1ip(1-261)[tAb] copptby[WB] xRap2a(G12V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xApbb1ip(1-261)[tAb] copptby[WB] xRras(G38V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xApbb1ip(1-261)[tAb] copptby[WB] xRras2(G23V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
*** Apc--
  *** rApc(221-958)[tAb] boundby[WB] rDvl1[tAb] is detectable
    *** cells: none
    *** source: 20224554-Fig-2f
  *** xApc(221-958)[tAb] copptby[WB] Dvls[Ab] is detectable
    *** cells: HEK293T<xApc(221-958)> in BMS
    *** source: 20224554-Fig-S16a
  *** xApc(221-958)[tAb] copptby[WB] Dvls[Ab] is detectable
    *** cells: HEK293T<xApc(221-958)> in BMS
    *** source: 20224554-Fig-S16c
  *** rApc(1342-2075)[32P] phos[32P-ATP] is increased by (pPKA + rGsk3b)
    *** cells: none
    *** reqs: pPKA [omission]
    *** source: 8638126-Fig-4a
  *** rApc(1342-2075)[32P] phos[32P-ATP] is increased by pPKA
    *** cells: none
    *** enhanced by: rGsk3b [addition]
    *** source: 8638126-Fig-4a
  *** rApc(1484-1528)"R3"[CB] boundby[WB] rCtnnb1(134-671)[GST] is unchanged by rAxin1(421-539)
    *** cells: none
    *** source: 15327768-Fig-5b
  *** Apc[Ab] copptby[WB] Ctnnb1[Ab] is decreased itpo xPin1
    *** cells: HELA in BMS
    *** source: 11533658-Fig-6a
  *** Apc[Ab] copptby[WB] Dvls[Ab] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xApc(221-958) [addition]
    *** source: 20224554-Fig-S16a
  *** Apc[Ab] copptby[WB] Dvls[Ab] is detectable
    *** cells: HELAS3 in BMS
    *** source: 20224554-Fig-2a
  *** Apc[Ab] copptby[WB] Tfap2a[Ab] is detectable
    *** cells: HCT116 in BMS
    *** source: 15331612-Fig-4c
  *** Apc[Ab] copptby[WB] Tfap2a[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 15331612-Fig-4c
  *** Apc[Ab] copptby[WB] Tfap2a[Ab] is detectable
    *** cells: HT29 in BMS
    *** source: 15331612-Fig-4c
  *** Apc[Ab] copptby[WB] xDvl2[tAb] is detectable
    *** cells: COS7<xDvl2> in BMS
    *** unaffected by: xDvl2(mnr)"delDEP" [substitution]
    *** unaffected by: xDvl2(1-509) [substitution]
    *** inhibited by: xDvl2(506-736) [substitution]
    *** source: 20224554-Fig-S14a
  *** Apc[Ab] copptby[WB] xFbxw2[tAb] is undetectable
    *** cells: HEK293T<xFbxw2><xAxin1> in BMS
    *** source: 10228155-Fig-3b
  *** Apc[Ab] copptby[WB] xMyc[Ab] is undetectable
    *** cells: HEK293<xAxin1><xMyc> in BMS
    *** source: 19131971-Fig-1d
  *** xApc[tAb] copptby[WB] xArhGef4[tAb] is detectable
    *** cells: A431 in BMLS
    *** unaffected by: xArhGef4(Y94F) [substitution]
    *** unaffected by: xArhGef4(Y94E) [substitution]
    *** unaffected by: xArhGef4(Y104E) [substitution]
    *** unaffected by: xArhGef4(Y94E/Y94E) [substitution]
    *** source: 18653540-Fig-S6
*** Apoe--
  *** Apoe-gene mRNA[Northern] is detectable
    *** cells: mSpBC in BMS
    *** partially reqs: Stat6 [KO]
    *** source: 11801631-Fig-2
*** Araf--
  *** xAraf[His]IP boundby[WB] rYwhaz[GST] is detectable
    *** cells: none
    *** IPfrom: SF9<xAraf> in BMS
    *** source: 14688280-Fig-7c
  *** xAraf[tAb] copptby[WB] xKras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1e
  *** xAraf[tAb] copptby[WB] xMras(H81L)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xShoc2 [addition]
    *** source: 16630891-Fig-3a
  *** xAraf[tAb] copptby[WB] xMras(Q81L)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1e
  *** xAraf[tAb] copptby[WB] xMras[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 16630891-Fig-3a
  *** xAraf[tAb] copptby[WB] xNras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1e
  *** xAraf[tAb] copptby[WB] xRap1a(G12V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1e
  *** xAraf[tAb] copptby[WB] xRap2a(G12V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1e
  *** xAraf[tAb] copptby[WB] xRras(G38V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1e
  *** xAraf[tAb] copptby[WB] xRras2(G38V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1e
  *** xAraf[tAb] locatedin(cellmembrane)[IHC] is increased itpo xHras(G12V)"CA"
    *** cells: MDCK in BMS
    *** source: 9020159-Fig-1
  *** xAraf[tAb]IP IVKA(Mek?,Erk2)[32P-ATP] is increased itpo xHras(G12V)"CA"
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1b
  *** xAraf[tAb]IP IVKA(Mek?,Erk2)[32P-ATP] is increased itpo xKras(G12V)"CA"
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1b
  *** xAraf[tAb]IP IVKA(Mek?,Erk2)[32P-ATP] is increased itpo xMras(Q81L)"CA"
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1b
  *** xAraf[tAb]IP IVKA(Mek?,Erk2)[32P-ATP] is increased itpo xNras(G12V)"CA"
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1b
  *** xAraf[tAb]IP IVKA(Mek1,Erk2,MBP)[32P-ATP] is unchanged itpo xHras(G12R)"CA"
    *** cells: COS7 in BMS
    *** source: 9020159-Fig-2b
  *** xAraf[tAb]IP IVKA(Mek1,Erk2,MBP)[32P-ATP] is unchanged itpo xSrc(Y527F)"CA"
    *** cells: COS7 in BMS
    *** source: 9020159-Fig-2b
  *** xAraf[tAb]IP IVKA(Mek1,Erk2)[32P-ATP] is unchanged itpo xRap1a(G12V)"CA"
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1a
  *** xAraf[tAb]IP IVKA(Mek1,Erk2)[32P-ATP] is unchanged itpo xRap2a(G12V)"CA"
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1a
  *** xAraf[tAb]IP IVKA(Mek1,Erk2)[32P-ATP] is unchanged itpo xRheb(Q64L)"CA"
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1a
  *** xAraf[tAb]IP IVKA(Mek1,Erk2)[32P-ATP] is unchanged itpo xRin1(A78L)"CA"
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1a
  *** xAraf[tAb]IP IVKA(Mek1,Erk2)[32P-ATP] is unchanged itpo xRit1(Q79L)"CA"
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1a
  *** xAraf[tAb]IP IVKA(Mek1,Erk2)[32P-ATP] is unchanged itpo xRras(G12V)"CA"
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1a
  *** xAraf[tAb]IP IVKA(Mek1,Erk2)[32P-ATP] is unchanged itpo xRras2(G23V)"CA"
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1a
  *** xAraf[tAb]IP IVKA(Mek2,Erk2,MBP)[32P-ATP] is unchanged itpo xHras(G12R)"CA"
    *** cells: COS7 in BMS
    *** source: 9020159-Fig-2b
  *** xAraf[tAb]IP IVKA(Mek2,Erk2,MBP)[32P-ATP] is unchanged itpo xSrc(Y527F)"CA"
    *** cells: COS7 in BMS
    *** source: 9020159-Fig-2b
  *** rArd1 GTP-hydrolysis[32P-GTP] is unchanged by rArfGap1
    *** cells: none
    *** source: 10788515-Fig-5a
  *** rArd1 GTP-hydrolysis[32P-GTP] is unchanged by rGit1
    *** cells: none
    *** source: 10788515-Fig-5a
  *** rArd1 GTP-hydrolysis[32P-GTP] is unchanged by rGit2-short
    *** cells: none
    *** source: 10788515-Fig-5a
*** Ard1--
  *** rArf1 GTP-hydrolysis[32P-release] is increased by rGit2
    *** cells: none
    *** source: 10896954-Fig-5
*** Arf1--
*** Arf4--
  *** xArf4[tAb] locatedin(cytoplasm)[IHC] is detectable
    *** cells: HEK293T<xEgfR> in BMLS
    *** source: 12446727-Fig-2
  *** rArf6 GTP-hydrolysis[32P-GTP] is unchanged by rArfGap1
    *** cells: none
    *** source: 10788515-Fig-5a
  *** rArf6 GTP-hydrolysis[32P-GTP] is unchanged by rArfGap1
    *** cells: none
    *** source: 10788515-Fig-5b
  *** rArf6 GTP-hydrolysis[32P-GTP] is unchanged by rArfGap1
    *** cells: none
    *** unaffected by: rArf6(myr) [substitution]
    *** source: 10788515-Fig-6a
*** Arf6--
  *** rArf6(myr) GTP-hydrolysis[32P-GTP] is unchanged by rArfGap1
    *** cells: none
    *** source: 10788515-Fig-6b
*** ArhGap5--
  *** ArhGap5[Ab] copptby[WB] Pxn[Ab] is detectable
    *** cells: hMesangialCells in BMS
    *** comment: coppt is not detectable when cells are held in suspension
    *** source: 10092539-Fig-3
*** ArhGdia--
  *** xArhGdia[tAb] copptby[WB] xCdc42(Q61L)[tAb] is increased itpo xSrc(Y530F)"CA"
    *** cells: COS7<xSrc> in BMS
    *** inhibited by: xCdc42(Q61L/Y64F) [substitution] no-bkg-control
    *** inhibited by: xCdc42(Q61L/Y64E) [substitution] no-bkg-control
    *** source: 14506284-Fig-4
  *** xArhGdia[tAb] copptby[WB] xCdc42[tAb] is increased itpo xSrc(Y530F)"CA"
    *** cells: COS7<xSrc> in BMS
    *** unaffected by: xCdc42(Q61L)"CA" [substitution]
    *** source: 14506284-Fig-4
*** ArhGef2--
  *** rArhGef2(226-643)[His] boundby[WB] rCdc42{NucFree}[GST] is undetectable
    *** cells: none
    *** source: 11595749-Fig-1b
  *** rArhGef2(226-643)[His] boundby[WB] rCdc42{NucFree}[GST] is undetectable
    *** cells: none
    *** source: 11595749-Fig-2b
  *** rArhGef2(226-643)[His] boundby[WB] rCdc42{NucFree}[GST] is undetectable
    *** cells: none
    *** source: 11595749-Fig-2c
  *** rArhGef2(226-643)[His] boundby[WB] rRac1{NucFree}[GST] is detectable
    *** cells: none
    *** partially inhibited by: rRac1(A59G) [substitution]
    *** inhibited by: rRac1(Q61L) [substitution]
    *** inhibited by: rRac1(Y64A) [substitution]
    *** partially inhibited by: rRac1(D65A) [substitution]
    *** inhibited by: rRac1(R66A/L67A) [substitution]
    *** partially inhibited by: rRac1(L70A/S71A) [substitution]
    *** partially inhibited by: rRac1(Q47D) [substitution]
    *** source: 11595749-Fig-2a
  *** rArhGef2(226-643)[His] boundby[WB] rRac1{NucFree}[GST] is detectable
    *** cells: none
    *** partially inhibited by: rRac1(E31A) [substitution]
    *** partially inhibited by: rRac1(Y32A) [substitution]
    *** partially inhibited by: rRac1(I33A) [substitution]
    *** partially inhibited by: rRac1(T35A) [substitution]
    *** inhibited by: rRac1(D38A) [substitution]
    *** inhibited by: rRac1(N39A) [substitution]
    *** source: 11595749-Fig-2a
  *** rArhGef2(226-643)[His] boundby[WB] rRac1{NucFree}[GST] is detectable
    *** cells: none
    *** source: 11595749-Fig-1b
  *** xArhGef2[tAb] snaggedby[WB] rCdc42(G15N)"NucFree"[GST] is undetectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-1
  *** xArhGef2[tAb] snaggedby[WB] rRac1(G15N)"NucFree"[GST] is undetectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-1
  *** xArhGef2[tAb] snaggedby[WB] rRhoa(G17A)"NucFree"[GST] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-1
  *** xArhGef2[tAb] snaggedby[WB] rRhog(G15N)"NucFree"[GST] is undetectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-1
*** ArhGef4--
  *** xArhGef4[tAb]IP Yphos[pYAb] is increased itpo xAbl1
    *** cells: A431 in BMLS
    *** source: 18653540-Fig-6b
  *** xArhGef6[tAb] prot-exp[WB] is detectable
    *** cells: COS7<xArhGef6> in BMLS
    *** comment: this has a second band at 2X MW which author says is dimerization
    *** comment: dimer is not seen when xArhGef6(L711R/L718S)"LZm" is substituted
    *** source: 15306850-Fig-5a
  *** xArhGef6[tAb] snaggedby[WB] rCdc42(T17N)[GST] is undetectable
    *** cells: COS7<xArhGef6> in BMLS
    *** source: 15306850-Fig-2b
*** ArhGef7--
  *** xArhGef7[Ab] prot-exp[WB] is decreased itpo xCbl
    *** cells: HEK293T<xArhGef7> in BMLS
    *** reversed by: xCbl(R829A) [substitution]
    *** source: 16407834-Fig-4b
  *** xArhGef7[Ab] prot-exp[WB] is decreased itpo xCdc42
    *** cells: HEK293T<xArhGef7> in BMLS
    *** source: 16407834-Fig-4b
  *** xArhGef7[Ab] prot-exp[WB] is decreased itpo xCdc42
    *** cells: HEK293T<xArhGef7><xCbl> in BMLS
    *** source: 16407834-Fig-4a
  *** xArhGef7[Ab] prot-exp[WB] is increased itpo xPak1
    *** cells: HEK293T<xArhGef7><xCbl> in BMLS
    *** source: 16407834-Fig-4a
  *** xArhGef7[Ab] prot-exp[WB] is increased itpo xRac1
    *** cells: HEK293T<xArhGef7><xCbl> in BMLS
    *** source: 16407834-Fig-4a
  *** xArhGef7[Ab]IP prot-exp[WB] is decreased itpo xCdc42
    *** cells: HEK293T<xArhGef7><xCbl> in BMLS
    *** source: 16407834-Fig-4c
  *** xArhGef7[Ab]IP prot-stability[35S-pulse-chase] is decreased itpo xCbl
    *** cells: HEK293T<xArhGef7> in BMLS "treated with Egf"
    *** source: 16407834-Fig-4c
  *** xArhGef7[tAb] copptby[WB] xArhGef6[tAb] is detectable
    *** cells: COS7<xArhGef7><xArhGef6> in BMLS
    *** inhibited by: xArhGef6(L711R/L718S)"LZm" [substitution]
    *** source: 15306850-Fig-5b
  *** xArhGef7[tAb] ubiq[tUbAb] is increased itpo xCbl
    *** cells: HEK293T<xArhGef7><xUbiq> in BMLS
    *** source: 16407834-Fig-3f
  *** xArhGef7[tAb]IP Yphos[pYAb] is increased itpo xFak1
    *** cells: NIH3T3 in BMLS
    *** inhibited by: xArhGef7(Y619F) [substitution]
    *** source: 16892055-Fig-2h
  *** xArhGef7[tAb]IP Yphos[pYAb] is increased itpo xFak1
    *** cells: NIH3T3 in BMLS
    *** inhibited by: xFak1(mnr)"KD" [substitution]
    *** source: 16892055-Fig-2h
*** ArhGef11--
  *** xArhGef11[tAb] copptby[WB] xMlk3[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 18851832-Fig-4a
  *** xArhGef12[tAb] copptby[WB] xMlk3[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 18851832-Fig-4b
  *** xArhGef12[tAb] snaggedby[WB] rCdc42(G15N)"NucFree"[GST] is undetectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-1
  *** xArhGef12[tAb] snaggedby[WB] rRac1(G15N)"NucFree"[GST] is undetectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-1
  *** xArhGef12[tAb] snaggedby[WB] rRhoa(G17A)"NucFree"[GST] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-1
  *** xArhGef12[tAb] snaggedby[WB] rRhog(G15N)"NucFree"[GST] is undetectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-1
  *** rArl1 GTP-hydrolysis[32P-GTP] is unchanged by rArfGap1
    *** cells: none
    *** source: 10788515-Fig-5a
  *** rArl1 GTP-hydrolysis[32P-GTP] is unchanged by rGit1
    *** cells: none
    *** source: 10788515-Fig-5a
  *** rArl1 GTP-hydrolysis[32P-GTP] is unchanged by rGit2-short
    *** cells: none
    *** source: 10788515-Fig-5a
  *** rArl2 GTP-hydrolysis[32P-GTP] is unchanged by rArfGap1
    *** cells: none
    *** source: 10788515-Fig-5a
  *** rArl2 GTP-hydrolysis[32P-GTP] is unchanged by rGit1
    *** cells: none
    *** source: 10788515-Fig-5a
  *** rArl2 GTP-hydrolysis[32P-GTP] is unchanged by rGit2-short
    *** cells: none
    *** source: 10788515-Fig-5a
  *** xArms[Ab] copptby[WB] xCrkL[tAb] is detectable
    *** cells: HEK293<xArms><xCrkL> in BMS
    *** enhanced by: xTrka [addition]
    *** source: 15167895-Fig-5d
  *** Arms[Ab] copptby[Xlink] Trks[Ab] is detectable
    *** cells: rECNs in BMS
    *** source: 15167895-Fig-2c
*** Arrb1--
  *** xArrb1(Q394L)[XFP] locatedin(cytoplasm)[IHC] is detectable
    *** cells: HEK293<xArrb1(Q394L)><xOpRd1> in BMS
    *** source: 16325578-Fig-1a
  *** Arrb1[Ab] boundto(Cdkn1b-gene)[ChIP] is detectable
    *** cells: HELA in BMS
    *** source: 16325578-Fig-3a
  *** xArrb1[Ab] boundto(Cdkn1b-gene)[ChIP] is detectable
    *** cells: mEFs<Arrb1~null><Arrb2~null><xArrb1> in BMS
    *** source: 16325578-Fig-3a
  *** Arrb1[Ab] boundto(Fos-gene)[ChIP] is detectable
    *** cells: HELA in BMS
    *** partially reqs: Creb1 [RNAi]
    *** source: 16325578-Fig-6d
  *** Arrb1[Ab] boundto(Fos-gene)[ChIP] is detectable
    *** cells: HELA in BMS
    *** source: 16325578-Fig-3a
  *** xArrb1[Ab] boundto(Fos-gene)[ChIP] is detectable
    *** cells: mEFs<Arrb1~null><Arrb2~null><xArrb1> in BMS
    *** source: 16325578-Fig-3a
  *** Arrb1[Ab] boundto(Jun-gene)[ChIP] is undetectable
    *** cells: HELA in BMS
    *** source: 16325578-Fig-3a
  *** Arrb1[Ab] boundto(Jun-gene)[ChIP] is undetectable
    *** cells: HELA in BMS
    *** source: 16325578-Fig-6d
  *** xArrb1[Ab] boundto(Jun-gene)[ChIP] is undetectable
    *** cells: mEFs<Arrb1~null><Arrb2~null><xArrb1> in BMS
    *** source: 16325578-Fig-3a
  *** Arrb1[Ab] boundto(S6k1-gene)[ChIP] is detectable
    *** cells: HELA in BMS
    *** partially reqs: Creb1 [RNAi]
    *** source: 16325578-Fig-6d
  *** Arrb1[Ab] copptby[WB] Creb1[Ab] is detectable
    *** cells: HELA in BMS
    *** source: 16325578-Fig-6c
  *** Arrb1[Ab] copptby[WB] Ep300[Ab] is detectable
    *** cells: HELA in BMS "nuclear-extracts"
    *** source: 16325578-Fig-4c
  *** xArrb1[XFP] locatedin(nucleus-cytoplasm)[IHC] is detectable
    *** cells: HEK293<xArrb1><xAdRb2> in BMS
    *** source: 16325578-Fig-S1a
  *** xArrb1[XFP] locatedin(nucleus-cytoplasm)[IHC] is detectable
    *** cells: HEK293<xArrb1><xOpRd1> in BMS
    *** source: 16325578-Fig-1a
  *** xArrb1[XFP] locatedin(nucleus-cytoplasm)[IHC] is detectable
    *** cells: HEK293<xArrb1><xOpRd1> in BMS
    *** source: 16325578-Fig-S1a
  *** xArrb1[XFP] locatedin(nucleus-cytoplasm)[IHC] is detectable
    *** cells: HEK293<xArrb1><xOpRk1> in BMS
    *** source: 16325578-Fig-S1a
  *** xArrb1[XFP] locatedin(nucleus-cytoplasm)[IHC] is detectable
    *** cells: HEK293<xArrb1><xOpRm1> in BMS
    *** source: 16325578-Fig-S1a
*** Arrb2--
  *** xArrb2[XFP] locatedin(cytoplasm)[IHC] is detectable
    *** cells: HEK293<xArrb2><xOpRd1> in BMS
    *** source: 16325578-Fig-1a
*** Asap1--
  *** Asap1[Ab] copptby[WB] Reps2[Ab] is detectable
    *** cells: CHO<xInsR> in BMS
    *** source: 12149250-Fig-2a
  *** xAsap1[tAb] copptby[WB] xPxn[GST] is detectable
    *** cells: CHO<xInsR><xAsap1><xPxn> in BMS
    *** unaffected by: xReps2 [addition]
    *** source: 12149250-Fig-6a
  *** xAsap1[tAb] copptby[WB] xRalbp1[tAb] is detectable
    *** cells: CHO<xInsR><xRalbp1><xAsap1> in BMS
    *** enhanced by: xReps2 [addition]
    *** inhibited by: xReps2(P423A/P426A) [addition]
    *** source: 12149250-Fig-5b
  *** xAsap1[tAb] copptby[WB] xReps2[tAb] is detectable
    *** cells: CHO<xInsR><xReps2><xAsap1> in BMS
    *** inhibited by: xReps2(P423A/P426A) [substitution]
    *** source: 12149250-Fig-4c
  *** Asap2[Ab] copptby[WB] Reps2[Ab] is detectable
    *** cells: CHO<xInsR> in BMS
    *** source: 12149250-Fig-2a
  *** Asap2[Ab] prot-exp[WB] is detectable
    *** cells: COS7 in BMS
    *** source: 10749932-Fig-2a
  *** Asap2[Ab] prot-exp[WB] is detectable
    *** cells: HELA in BMS
    *** source: 10749932-Fig-2a
  *** Asap2[Ab] prot-exp[WB] is detectable
    *** cells: VERO in BMS
    *** source: 10749932-Fig-2a
  *** Asap2[Ab] prot-exp[WB] is undetectable
    *** cells: HEK293T in BMS
    *** source: 10749932-Fig-2a
  *** Asap2[Ab] prot-exp[WB] is undetectable
    *** cells: NIH3T3 in BMS
    *** source: 10749932-Fig-2a
  *** Asap2[Ab] prot-exp[WB] is undetectable
    *** cells: PC12 in BMS
    *** source: 10749932-Fig-2a
  *** Asap2[Ab]IP Yphos[pYAb] is detectable
    *** cells: U937 in BMS
    *** source: 10749932-Fig-2b
  *** Asap2[Ab]IP Yphos[pYAb] is detectable
    *** cells: U937 in BMS "treated with PMA for 3 days"
    *** source: 10749932-Fig-2b
  *** Ascl2-gene mRNA[RTPCR] is detectable
    *** cells: DLD1 in BMS
    *** partially reqs: Mekk1 [RNAi]
    *** source: 20128690-Fig-4b
*** Ask1--
  *** rAsk1[35S] boundby[WB] rGadd45b[GST] is detectable
    *** cells: none
    *** source: 14743220-Fig-1c
  *** rAsk1[35S] boundby[WB] rTxn[GST] is decreased by Diamide
    *** cells: none
    *** source: 9564042-Fig-6c
  *** rAsk1[35S] boundby[WB] rTxn[GST] is decreased by H2O2
    *** cells: none
    *** source: 9564042-Fig-6c
  *** Ask1[Ab] prot-exp[WB] is increased itpo (xTLR4 + xCd4)
    *** cells: THP1 in BMS
    *** source: 18155167-Fig-2
  *** xAsk1[Ab]IP IVKA(Mkk3,P38?,Atf2)[32P-ATP] is detectable
    *** cells: COS7 in BMS
    *** source: 8974401-Fig-2c
  *** xAsk1[Ab]IP IVKA(Mkk4,P38?,Atf2)[32P-ATP] is detectable
    *** cells: COS7 in BMS
    *** source: 8974401-Fig-2c
  *** xAsk1[Ab]IP IVKA(Mkk4)[32P-ATP] is increased itpo xTraf2
    *** cells: HEK293 in BMS
    *** unaffected by: xUbc13(C87A)"E2-inactive" [addition]
    *** source: 12591926-Fig-3
  *** xAsk1[Ab]IP IVKA(Mkk6,P38?,Atf2)[32P-ATP] is detectable
    *** cells: COS7 in BMS
    *** source: 8974401-Fig-2c
  *** xAsk1[tAb] copptby[WB] Fak2[Ab] is undetectable
    *** cells: HEK293 in BMS
    *** source: 9564042-Fig-6d
  *** xAsk1[tAb] copptby[WB] Ripk1[Ab] is undetectable
    *** cells: HEK293T in BMS
    *** source: 14585994-Fig-4a
  *** xAsk1[tAb] copptby[WB] xGadd45b[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 14743220-Fig-1a
  *** xAsk1[tAb] copptby[WB] xTraf1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 9774977-Fig-1b
  *** xAsk1[tAb] copptby[WB] xTraf2[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 9774977-Fig-1b,1c
  *** xAsk1[tAb] copptby[WB] xTraf3[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 9774977-Fig-1b
  *** xAsk1[tAb] copptby[WB] xTraf5[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 9774977-Fig-1b
  *** xAsk1[tAb] copptby[WB] xTraf6[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 9774977-Fig-1b
  *** xAsk1[tAb]IP IVKA(Mkk6,P38g,Atf2)[32P-ATP] is detectable
    *** cells: HEK293 in BMS
    *** source: 9564042-Fig-2a
  *** xAsk1[tAb]IP IVKA(Mkk6,P38g)[32P-ATP] is increased itpo xTraf2
    *** cells: HEK293 in BMS
    *** source: 9774977-Fig-1a
  *** xAsk1[tAb]IP IVKA(Mkk6,P38g)[32P-ATP] is increased itpo xTraf6
    *** cells: HEK293 in BMS
    *** source: 9774977-Fig-1a
  *** xAsk1[tAb]IP IVKA(Mkk6,P38g)[32P-ATP] is unchanged itpo xTraf1
    *** cells: HEK293 in BMS
    *** source: 9774977-Fig-1a
  *** xAsk1[tAb]IP IVKA(Mkk6,P38g)[32P-ATP] is unchanged itpo xTraf3
    *** cells: HEK293 in BMS
    *** source: 9774977-Fig-1a
  *** xAsk1[tAb]IP IVKA(Mkk6,P38g)[32P-ATP] is unchanged itpo xTraf5
    *** cells: HEK293 in BMS
    *** source: 9774977-Fig-1a
*** Atf1--
*** Atf2--
  *** rAtf2(1-125)[32P] phos[32P-ATP] is increased by rPkca
    *** cells: none
    *** inhibited by: rAtf2(1-125/S121A) [substitution]
    *** unaffected by: rAtf2(1-125/T69A/T71A) [substitution]
    *** inhibited by: rAtf2(1-125/S121A/T69A/T71A) [substitution]
    *** source: 19176525-Fig-4a
  *** rAtf2(111-123)[32P] phos[32P-ATP] is increased by pCPkcs
    *** cells: none
    *** inhibited by: rAtf2(111-123/S121A) [substitution]
    *** comment: phos on this peptide is weaker than phos on the S340S and S367 peptides
    *** source: 19176525-Fig-2c
  *** rAtf2(111-123)[32P] phos[32P-ATP] is increased by rPkca
    *** cells: none
    *** inhibited by: rAtf2(111-123/S121A) [substitution]
    *** comment: phos on this peptide is weaker than phos on the S340S and S367 peptides
    *** source: 19176525-Fig-2e
  *** rAtf2(111-123)[32P] phos[32P-ATP] is increased by rPkcb
    *** cells: none
    *** inhibited by: rAtf2(111-123/S121A) [substitution]
    *** comment: phos on this peptide is weaker than phos on the S340S and S367 peptides
    *** source: 19176525-Fig-2e
  *** rAtf2(111-123)[32P] phos[32P-ATP] is unchanged by rPkcb2
    *** cells: none
    *** inhibited by: rAtf2(111-123/S121A) [substitution]
    *** source: 19176525-Fig-2e
  *** rAtf2(111-123)[32P] phos[32P-ATP] is unchanged by rPkcd
    *** cells: none
    *** inhibited by: rAtf2(111-123/S121A) [substitution]
    *** source: 19176525-Fig-2k
  *** rAtf2(111-130)[32P] phos[32P-ATP] is increased by pCPkcs
    *** cells: none
    *** inhibited by: rAtf2(111-130/S121A) [substitution]
    *** comment: phos on this peptide is weaker than phos on the S340S and S367 peptides
    *** source: 19176525-Fig-2c
  *** rAtf2(111-130)[32P] phos[32P-ATP] is increased by rPkca
    *** cells: none
    *** inhibited by: rAtf2(111-130/S121A) [substitution]
    *** comment: phos on this peptide is weaker than phos on the S340S and S367 peptides
    *** source: 19176525-Fig-2e
  *** rAtf2(111-130)[32P] phos[32P-ATP] is increased by rPkcb
    *** cells: none
    *** inhibited by: rAtf2(111-130/S121A) [substitution]
    *** comment: phos on this peptide is weaker than phos on the S340S and S367 peptides
    *** source: 19176525-Fig-2e
  *** rAtf2(111-130)[32P] phos[32P-ATP] is increased by rPkcd
    *** cells: none
    *** unaffected by: rAtf2(111-130/S121A) [substitution]
    *** source: 19176525-Fig-2k
  *** rAtf2(111-130)[32P] phos[32P-ATP] is unchanged by rPkcb2
    *** cells: none
    *** inhibited by: rAtf2(111-130/S121A) [substitution]
    *** source: 19176525-Fig-2e
  *** rAtf2(332-351)[32P] phos[32P-ATP] is increased by pCPkcs
    *** cells: none
    *** inhibited by: rAtf2(332-351/S340A) [substitution]
    *** source: 19176525-Fig-2c
  *** rAtf2(332-351)[32P] phos[32P-ATP] is increased by rPkca
    *** cells: none
    *** inhibited by: rAtf2(332-351/S340A) [substitution]
    *** source: 19176525-Fig-2e
  *** rAtf2(332-351)[32P] phos[32P-ATP] is increased by rPkcb
    *** cells: none
    *** inhibited by: rAtf2(332-351/S340A) [substitution]
    *** source: 19176525-Fig-2e
  *** rAtf2(332-351)[32P] phos[32P-ATP] is increased by rPkcb2
    *** cells: none
    *** inhibited by: rAtf2(332-351/S340A) [substitution]
    *** source: 19176525-Fig-2e
  *** rAtf2(332-351)[32P] phos[32P-ATP] is increased by rPkcd
    *** cells: none
    *** unaffected by: rAtf2(332-351/S340A) [substitution]
    *** source: 19176525-Fig-2k
  *** rAtf2(357-376)[32P] phos[32P-ATP] is increased by pCPkcs
    *** cells: none
    *** inhibited by: rAtf2(357-376/S367A) [substitution]
    *** source: 19176525-Fig-2c
  *** rAtf2(357-376)[32P] phos[32P-ATP] is increased by rPkca
    *** cells: none
    *** inhibited by: rAtf2(357-376/S367A) [substitution]
    *** source: 19176525-Fig-2e
  *** rAtf2(357-376)[32P] phos[32P-ATP] is increased by rPkcb
    *** cells: none
    *** inhibited by: rAtf2(357-376/S367A) [substitution]
    *** source: 19176525-Fig-2e
  *** rAtf2(357-376)[32P] phos[32P-ATP] is increased by rPkcb2
    *** cells: none
    *** inhibited by: rAtf2(357-376/S367A) [substitution]
    *** source: 19176525-Fig-2e
  *** rAtf2(357-376)[32P] phos[32P-ATP] is increased by rPkcd
    *** cells: none
    *** inhibited by: rAtf2(357-376/S367A) [substitution]
    *** source: 19176525-Fig-2k
  *** xAtf2(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xHras(Q61L)"CA"
    *** cells: mEFs<Jnk1~null><Jnk2~null> in BMLS
    *** inhibited by: xAtf2(TAD/T69A/T71A) [substitution]
    *** source: 19647037-Fig-3b
  *** xAtf2(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xHras(Q61L)"CA"
    *** cells: NIH3T3<xInsR> in BMS
    *** inhibited by: xAtf2(T69A) [substitution]
    *** inhibited by: xAtf2(T71A) [substitution]
    *** inhibited by: xAtf2(T69A/T71A) [substitution]
    *** source: 12110590-Fig-2d
  *** xAtf2(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMap4k4
    *** cells: HEK293 in BMS
    *** inhibited by: xMap4k4(D152N)"KD" [substitution]
    *** inhibited by: xMap4k4(del(Cterm)) [substitution]
    *** source: 9135144-Fig-8b
  *** Atf2(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMekk1(mnr)"CA"
    *** cells: mESCs in BMS
    *** does not req: Med23 [KO]
    *** source: 11934987-Fig-3a
  *** xAtf2(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMkk3(S189E/T193E)"CA"
    *** cells: CHO in BMS
    *** source: 8663524-Fig-9
  *** xAtf2(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMkk6(S207E/T211E)"CA"
    *** cells: CHO in BMS
    *** source: 8663524-Fig-9
  *** xAtf2(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xRgl2(mnr)"CAAX"
    *** cells: mEFs<Jnk1~null><Jnk2~null> in BMLS
    *** inhibited by: xAtf2(TAD/T69A/T71A) [substitution]
    *** source: 19647037-Fig-3b
  *** rAtf2[32P] phos[32P-ATP] is increased by pCPkcs
    *** cells: none
    *** inhibited by: rAtf2(S121A) [substitution]
    *** source: 19176525-Fig-2b
  *** Atf2[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: HELA in BMS
    *** unaffected by: PMA (30 min) [stim]
    *** comment: Atf2 in nucleus is phosed on S340 [phosAb]
    *** comment: Atf2 in nucleus is phosed on S490/S498 [phosAb]
    *** comment: Atf2 in nucleus is phosed on T69/T71 [phosAb]
    *** source: 19176525-Fig-4c
  *** Atf2[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xTraf6
    *** cells: HEK293 in BMS
    *** enhanced by: xZnf274 [addition]
    *** source: 14960584-Fig-7a
  *** Atf2[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xTraf6
    *** cells: HEK293 in BMS
    *** enhanced by: xZnf274 [addition]
    *** source: 14960584-Fig-7b
  *** Atf2[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xZnf274
    *** cells: HEK293 in BMS
    *** enhanced by: xTraf6 [addition]
    *** source: 14960584-Fig-7a
  *** xAtf2[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xMek1(del(32-51)/S218E/S222D)
    *** cells: CHO in BMS
    *** source: 8622669-Fig-4b
  *** Atf2[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xTraf1
    *** cells: HEK293 in BMS
    *** unaffected by: xZnf274 [addition]
    *** source: 14960584-Fig-7b
  *** Atf2[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xTraf2
    *** cells: HEK293 in BMS
    *** unaffected by: xZnf274 [addition]
    *** source: 14960584-Fig-7b
  *** Atf2[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xTraf3
    *** cells: HEK293 in BMS
    *** unaffected by: xZnf274 [addition]
    *** source: 14960584-Fig-7b
  *** Atf2[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xTraf5
    *** cells: HEK293 in BMS
    *** unaffected by: xZnf274 [addition]
    *** source: 14960584-Fig-7b
  *** Atf2[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xZnf274
    *** cells: HEK293 in BMS
    *** source: 14960584-Fig-7b
  *** Atf2[phosAb] phos(T69/T71)[phosAb] is increased itpo xHras(Q61L)"CA"
    *** cells: mEFs<Jnk1~null><Jnk2~null> in BMLS
    *** source: 19647037-Fig-3a
  *** xAtf2[phosAb] phos(T69/T71)[phosAb] is increased itpo xHras(Q61L)"CA"
    *** cells: NIH3T3<xInsR> in BMLS
    *** source: 12110590-Fig-2c
  *** Atf2[phosAb] phos(T69/T71)[phosAb] is increased itpo xRaf1(mnr)"CAAX"
    *** cells: mEFs<Jnk1~null><Jnk2~null> in BMLS
    *** source: 19647037-Fig-3a
  *** Atf2[phosAb] phos(T69/T71)[phosAb] is increased itpo xRgl2(mnr)"CAAX"
    *** cells: mEFs<Jnk1~null><Jnk2~null> in BMLS
    *** source: 19647037-Fig-3a
  *** xAtf2[phosAb] phos(T69/T71)[phosAb] is increased itpo xRgl2(mnr)"CAAX"
    *** cells: mEFs<Jnk1~null><Jnk2~null> in BMLS
    *** unaffected by: U0126 [addition]
    *** source: 12110590-Fig-5f
  *** xAtf2[phosAb] phos(T69/T71)[phosAb] is increased itpo xRgl2(mnr)"CAAX"
    *** cells: NIH3T3<xInsR> in BMLS
    *** unaffected by: U0126 [addition]
    *** source: 12110590-Fig-5f
  *** Atf2[phosAb] phos(T71)[phosAb] is increased itpo xHras(Q61L)"CA"
    *** cells: mEFs<Jnk1~null><Jnk2~null> in BMLS
    *** source: 19647037-Fig-3a
  *** Atf2[phosAb] phos(T71)[phosAb] is increased itpo xRaf1(mnr)"CAAX"
    *** cells: mEFs<Jnk1~null><Jnk2~null> in BMLS
    *** source: 19647037-Fig-3a
  *** Atf2[phosAb] phos(T71)[phosAb] is increased itpo xRgl2(mnr)"CAAX"
    *** cells: mEFs<Jnk1~null><Jnk2~null> in BMLS
    *** source: 19647037-Fig-3a
*** Atf3--
  *** Atf3[Ab] prot-exp[WB] is increased itpo xSmad3
    *** cells: C2C12 in BMS
    *** unaffected by: xSmad3(T178V) [substitution]
    *** enhanced by: xSmad3(S203A) [substitution]
    *** enhanced by: xSmad3(S207A) [substitution]
    *** enhanced by: xSmad3(S203A/S207A) [substitution]
    *** unaffected by: xSmad3(T178V/S203A/S207A) [substitution]
    *** source: 16156666-Fig-6
*** Atg3--
  *** xAtg3[tAb] copptby[WB] xAtg7[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 11825910(D)
  *** xAtg5[XFP] colocwith[IHC] Atg12[Ab] is detectable
    *** cells: mESCs in BMS
    *** inhibited by: xAtg5(K130R) [substitution]
    *** source: 11266458(D)
  *** xAtg7[Ab] copptby[WB] xAtg10[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 12890687(D)
  *** xAtg7[tAb] copptby[WB] xAtg3[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 11825910(D)
  *** xAtg10[Ab] copptby[WB] xMap1lc3?[tAb] is detectable
    *** cells: HEK293<xAtg7> in BMS
    *** unaffected by: xAtg7 [omission]
    *** source: 12890687(D)
  *** xAtg10[tAb] copptby[WB] xAtg12[tAb] is detectable
    *** cells: HEK293<xAtg7> in BMS
    *** reqs: xAtg7 [omission]
    *** inhibited by: xAtg12(mnr)"DN" [substitution]
    *** source: 12890687(D)
  *** xAtg12[tAb] copptby[WB] xAtg3[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 11825910(D)
  *** xAtg12[tAb] copptby[WB] xAtg10[Ab] is detectable
    *** cells: HEK293<xAtg7> in BMS
    *** reqs: xAtg7 [omission]
    *** inhibited by: xAtg12(mnr)"DN" [substitution]
    *** source: 12890687(D)
*** Atm--
  *** xAtm(2678-3056)[tAb] copptby[WB] xRheb[GST] is detectable
    *** cells: HEK293T<xRheb><xAtm(2678-3056)> in BMS
    *** source: 15854902-Fig-4a
  *** Atm[Ab] copptby[WB] Atrip[Ab] is detectable
    *** cells: HELA in BMS "nuclear-extract"
    *** comment: IP was performed in the presence of linear dsDNA
    *** source: 15758953-Fig-S4b
  *** Atm[Ab] copptby[WB] Ku80[Ab] is undetectable
    *** cells: HELA in BMS "nuclear-extract"
    *** comment: IP was performed in the presence of linear dsDNA
    *** source: 15758953-Fig-S4b
  *** Atm[Ab] copptby[WB] Mdc1[Ab] is detectable
    *** cells: NBS1LBI<Nbs1~fmut><xNbs1> in BMS
    *** does not req: xNbs1 [omission]
    *** source: 16427009-Fig-S7
  *** Atm[Ab] copptby[WB] Nbs1[Ab] is detectable
    *** cells: HELA in BMS "nuclear-extract"
    *** comment: IP was performed in the presence of linear dsDNA
    *** source: 15758953-Fig-S4b
  *** Atm[Ab] copptby[WB] Nbs1[Ab] is detectable
    *** cells: NotReported in BMS "nuclear-extracts"
    *** comment: enhanced by additon of linear dsDNA to lysates before IP
    *** comment: unaffected by additon of circular dsDNA to lysates before IP
    *** source: 15758953-Fig-2d
  *** Atm[Ab] copptby[WB] Trrap[Ab] is undetectable
    *** cells: HELA in BMS
    *** source: 16141325-Fig-2e
  *** Atm[Ab] copptby[WB] xMdc1[tAb] is detectable
    *** cells: HEK293T<xMdc1> in BMS
    *** inhibited by: xMdc1(del(56-124))"delFHA" [substitution]
    *** source: 16427009-Fig-5e
  *** xAtm[Ab] copptby[WB] xNbs1[tAb] is detectable
    *** cells: NotReported<xAtm><xNbs1> in BMS
    *** inhibited by: xNbs1(1-734) [substitution]
    *** source: 15758953-Fig-1d
  *** xAtm[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: GM5849<Atm~fmut> in BMS
    *** unaffected by: xAtm(1-3032)"dFATC" [substitution]
    *** unaffected by: xAtm(chimera)"AtrFATC" [substitution]
    *** unaffected by: xAtm(chimera)"PrkdcFATC" [substitution]
    *** unaffected by: xAtm(chimera)"TrrapFATC" [substitution]
    *** source: 16603769-Fig-S1
  *** xAtm[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: GM5849<Atm~fmut><xAtm> in BMS
    *** unaffected by: xAtm(K3016R) [substitution]
    *** source: 17923702-Fig-S2
  *** Atm[Ab] snaggedby[WB] dsDNA[biotin] is detectable
    *** cells: NBS1LBI<Nbs1~fmut><xNbs1> in BMS
    *** reqs: xNbs1 [omission]
    *** inhibited by: xNbs1(1-734)"delC" [substitution]
    *** source: 15758953-Fig-2a
  *** Atm[Ab] snaggedby[WB] dsDNA[biotin] is detectable
    *** cells: NotReported in BMS
    *** comment: inhibited by addition of rNbs1(734-754) to the lysates
    *** comment: unaffected by addition of rNbs1(675-697) to the lysates
    *** source: 15758953-Fig-2b
  *** Atm[Ab] snaggedby[WB] rAtrip(765-791)[biotin] is detectable
    *** cells: HELA in BMS "nuclear-extract"
    *** source: 15758953-Fig-S4a
  *** Atm[Ab] snaggedby[WB] rKu80(718-732)[biotin] is detectable
    *** cells: HELA in BMS "nuclear-extract"
    *** source: 15758953-Fig-S4a
  *** Atm[Ab] snaggedby[WB] rMdc1(56-124)"FHA"[GST] is detectable
    *** cells: HEK293T in BMS
    *** source: 16427009-Fig-5c
  *** Atm[Ab] snaggedby[WB] rMdc1(56-124)"FHA"[GST] is detectable
    *** cells: NBS1LBI<Nbs1~fmut><xNbs1> in BMS
    *** does not req: xNbs1 [omission]
    *** source: 16427009-Fig-S6
  *** Atm[Ab] snaggedby[WB] rMdc1(1894-2089)"BRCT"[GST] is undetectable
    *** cells: HEK293T in BMS
    *** source: 16427009-Fig-5b
  *** Atm[Ab] snaggedby[WB] rNbs1(734-754)[biotin] is detectable
    *** cells: HELA in BMS "nuclear-extract"
    *** inhibited by: rNbs1(675-697) [substitution]
    *** source: 15758953-Fig-1b
  *** Atm[Ab] snaggedby[WB] rNbs1(734-754)[biotin] is detectable
    *** cells: HELA in BMS "nuclear-extract"
    *** inhibited by: rNbs1(675-697) [substitution]
    *** source: 15758953-Fig-S4a
  *** Atm[Ab] snaggedby[WB] sH2ax(123-143){phos(S140)}[GST] is undetectable
    *** cells: HELA in BMS "nuclear-extracts"
    *** unaffected by: sH2ax(123-143) [substitution]
    *** source: 16377563-Fig-1b
  *** Atm[Ab] snaggedby[WB] sH2ax(134-143){phos(S140)}[GST] is detectable
    *** cells: NBS1LBI<Nbs1~fmut><xNbs1> in BMS
    *** does not req: xNbs1 [omission]
    *** source: 16427009-Fig-S5
  *** Atm[Ab] snaggedby[WB] sH2ax(134-143){phos(S140)}[Sepharose] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: sH2ax(134-143) [substitution]
    *** source: 16427009-Fig-4e
  *** Atm[Ab] snaggedby[WB] sH2ax(134-143){phos(S140)}[Sepharose] is detectable
    *** cells: mEFs in BMS
    *** inhibited by: sH2ax(134-143) [substitution]
    *** source: 16427009-Fig-4f
  *** Atm[Ab] snaggedby[WB] sH2ax(134-143){phos(S140)}[Sepharose] is detectable
    *** cells: mEFs in BMS
    *** reqs: Mdc1 [KO]
    *** source: 16427009-Fig-4f
  *** xAtm[Ab]IP boundby[WB] rMdc1(56-124)"FHA"[GST] is detectable
    *** cells: none
    *** source: 16427009-Fig-5d
  *** xAtm[Ab]IP boundby[WB] sH2ax(134-143){phos(S140)}[Sepharose] is detectable
    *** cells: none
    *** comment: reqs addition of rMdc1 to reaction
    *** source: 16427009-Fig-4g
  *** xAtm[Ab]IP IVKA(Eif4ebp1)[32P-ATP] is detectable
    *** cells: AT22IJET<Atm~null><xAtm> in BMS
    *** source: 9733514-Fig-1b
  *** Atm[Ab]IP IVKA(Eif4ebp1)[32P-ATP] is detectable
    *** cells: G361 in BMS
    *** source: 9733514-Fig-1a
  *** Atm[Ab]IP IVKA(Eif4ebp1)[32P-ATP] is detectable
    *** cells: L40 in BMS
    *** source: 9733514-Fig-1a
  *** Atm[Ab]IP IVKA(Eif4ebp1)[32P-ATP] is detectable
    *** cells: L40 in BMS
    *** source: 9733514-Fig-1c
  *** Atm[Ab]IP IVKA(Eif4ebp1)[32P-ATP] is detectable
    *** cells: NotReported in BMS
    *** comment: inhibited by pretreatment of IP with wortmannin
    *** source: 9733514-Fig-1c
  *** Atm[Ab]IP IVKA(Eif4ebp1)[32P-ATP] is undetectable
    *** cells: 9RM in BMS
    *** source: 9733514-Fig-1c
  *** Atm[Ab]IP IVKA(Eif4ebp1)[32P-ATP] is undetectable
    *** cells: 41RM in BMS
    *** source: 9733514-Fig-1c
  *** Atm[Ab]IP IVKA(Tp53)[32P-ATP] is undetectable
    *** cells: GM1526 in BMS
    *** source: 9733515-Fig-3a
  *** rAtm[SStain] boundby[WB] rNbs1(734-754)[biotin] is detectable
    *** cells: none
    *** inhibited by: rNbs1(675-697) [substitution]
    *** source: 15758953-Fig-S1b
  *** xAtm[tAb] copptby[WB] xNbs1[tAb] is detectable
    *** cells: NotReported<xAtm><xNbs1> in BMS
    *** inhibited by: xNbs1(1-734)"delC" [substitution]
    *** partially inhibited by: xNbs1(N684A/F685A/K686A/K687A)"dMIR" [substitution]
    *** source: 15758953-Fig-1e
  *** xAtm[tAb] copptby[WB] xNbs1[tAb] is detectable
    *** cells: NotReported<xAtm><xNbs1> in BMS
    *** inhibited by: xNbs1(E736A/E737A) [substitution]
    *** inhibited by: xNbs1(D741A/D742A) [substitution]
    *** inhibited by: xNbs1(R745A/Y746A) [substitution]
    *** source: 15758953-Fig-1e
  *** xAtm[tAb] oligomerization[2TagPpt] is detectable
    *** cells: GM9607<Atm~fmut><xAtm> in BMS
    *** unaffected by: xAtm(D2870A/N2875K)"KD" [substitution]
    *** unaffected by: xAtm(S1981A) [substitution]
    *** source: 17486112-Fig-1d
*** Atp6V0--
  *** xAtp6V0c[tAb] copptby[WB] xHif1a[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 17178925(D)
  *** xAtp6V0c[tAb] copptby[WB] xHif1a[tAb] is detectable
    *** cells: HEK293 in BMS "treated with MG132"
    *** enhanced by: Bafilomycin [addition]
    *** source: 17178925(D)
*** Atr--
  *** xAtr(2288-2644)[tAb] copptby[WB] xRheb[GST] is detectable
    *** cells: HEK293T<xRheb><xAtr(2288-2644)> in BMS
    *** source: 15854902-Fig-4a
  *** Atr[Ab] copptby[WB] Atrip[Ab] is detectable
    *** cells: HELA in BMS
    *** source: 16431910-Fig-S1
  *** Atr[Ab] copptby[WB] Atrip[Ab] is detectable
    *** cells: HELA in BMS "nuclear-extract"
    *** comment: IP was performed in the presence of linear dsDNA
    *** source: 15758953-Fig-S4b
  *** Atr[Ab] copptby[WB] Ku80[Ab] is undetectable
    *** cells: HELA in BMS "nuclear-extract"
    *** comment: IP was performed in the presence of linear dsDNA
    *** source: 15758953-Fig-S4b
  *** Atr[Ab] copptby[WB] Mre11[Ab] is undetectable
    *** cells: HELA in BMS
    *** source: 16431910-Fig-S1
  *** Atr[Ab] copptby[WB] Nbs1[Ab] is detectable
    *** cells: HELA in BMS "nuclear-extract"
    *** comment: IP was performed in the presence of linear dsDNA
    *** source: 15758953-Fig-S4b
  *** Atr[Ab] copptby[WB] Nbs1[Ab] is undetectable
    *** cells: HELA in BMS
    *** source: 16431910-Fig-S1
  *** Atr[Ab] copptby[WB] Nemo[Ab] is undetectable
    *** cells: HEK293 in BMS
    *** source: 16497931-Fig-2f
  *** Atr[Ab] snaggedby[WB] rAtrip(765-791)[biotin] is detectable
    *** cells: HELA in BMS "nuclear-extract"
    *** source: 15758953-Fig-S4a
  *** Atr[Ab] snaggedby[WB] rKu80(718-732)[biotin] is detectable
    *** cells: HELA in BMS "nuclear-extract"
    *** source: 15758953-Fig-S4a
  *** Atr[Ab] snaggedby[WB] rNbs1(734-754)[biotin] is detectable
    *** cells: HELA in BMS "nuclear-extract"
    *** inhibited by: rNbs1(675-697) [substitution]
    *** source: 15758953-Fig-S4a
  *** xAtr[Ab] snaggedby[WB] ssDNA[biotin] is detectable
    *** cells: HEK293T<xAtrip> in BMS
    *** comment: Atrip was knocked-down with RNAi
    *** comment: xAtrip was RNAi-resistant
    *** reqs: xAtrip [omission]
    *** inhibited by: xAtrip(1-768)"delC" [substitution]
    *** source: 15758953-Fig-5c
  *** xAtr[tAb] copptby[WB] xAtrip[tAb] is detectable
    *** cells: NotReported<xAtrip><xAtr> in BMS
    *** inhibited by: xAtrip(1-768)"delC" [substitution]
    *** inhibited by: xAtrip(E769A/E770A) [substitution]
    *** inhibited by: xAtrip(D774A/D775A) [substitution]
    *** source: 15758953-Fig-5b
  *** xAtr[tAb]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xAtr(D2870A/N2875K)"KD" [substitution]
    *** source: 9733515-Fig-1a
  *** Atrip[Ab] copptby[WB] Ku80[Ab] is undetectable
    *** cells: HELA in BMS "nuclear-extract"
    *** comment: IP was performed in the presence of linear dsDNA
    *** source: 15758953-Fig-S4b
  *** Atrip[Ab] copptby[WB] Mre11[Ab] is detectable
    *** cells: HELA in BMS
    *** source: 16431910-Fig-S1
  *** Atrip[Ab] copptby[WB] Nbs1[Ab] is detectable
    *** cells: HELA in BMS
    *** source: 16431910-Fig-S1
  *** Atrip[Ab] copptby[WB] Nbs1[Ab] is undetectable
    *** cells: HELA in BMS "nuclear-extract"
    *** comment: IP was performed in the presence of linear dsDNA
    *** source: 15758953-Fig-S4b
  *** xAtrip[Ab] snaggedby[WB] ssDNA[biotin] is detectable
    *** cells: HEK293T<xAtrip> in BMS
    *** comment: Atrip was knocked-down with RNAi
    *** comment: xAtrip was RNAi-resistant
    *** unaffected by: xAtrip(1-768)"delC" [substitution]
    *** source: 15758953-Fig-5c
  *** xAtrip[tAb] copptby[WB] xAtr[tAb] is detectable
    *** cells: NotReported<xAtrip><xAtr> in BMS
    *** inhibited by: xAtrip(1-768)"delC" [substitution]
    *** inhibited by: xAtrip(E769A/E770A) [substitution]
    *** inhibited by: xAtrip(D774A/D775A) [substitution]
    *** source: 15758953-Fig-5b
  *** xAxin?[Ab] copptby[WB] xAdrbk?[tAb] is undetectable
    *** cells: HEK293<xAdrbk?><xAxin?> in BMS
    *** source: 20460648-Fig-S6
  *** xAxin?[tAb] copptby[WB] xGnb1[Ab] is detectable 
    *** cells: HEK293<xAxin?><xGnb1><xGng2> in BMS
    *** source: 20460648-Fig-6f
*** Axin1--
  *** rAxin1(421-539)[CB] boundby[WB] rCtnnb1(134-671)[GST] is decreased by rApc(1484-1528)"R3"{phos}
    *** cells: none
    *** comment: rApc(1484-1528) was phosed by Csnk1e and Gsk3b
    *** source: 15327768-Fig-5b
  *** Axin1[Ab] copptby[WB] Mekk4[Ab] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xAxin1(del(210-338))"Mekk4-binding-region-mut" [addition]
    *** source: 12878610-Fig-3
  *** Axin1[Ab] copptby[WB] Myc[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 19131971-Fig-1b
  *** Axin1[Ab] copptby[WB] Sp1[Ab] is undetectable
    *** cells: HEK293 in BMS
    *** source: 19131971-Fig-1b
  *** xAxin1[tAb] boundto(E2f2-gene)[ChIP] is detectable
    *** cells: HEK293 in BMLS
    *** source: 19131971-Fig-4c
  *** xAxin1[tAb] copptby[WB] xCdkn1c[tAb] is undetectable
    *** cells: HEK293T<xCdkn1c><xAxin1> in BMS
    *** source: 10228155-Fig-1a
  *** xAxin1[tAb] copptby[WB] xDixdc1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15262978-Fig-4a
  *** xAxin1[tAb] copptby[WB] xDvl1[tAb] is decreased itpo xFrat1
    *** cells: COS<xAxin1><xDvl1><xCsnk1e> in BMS
    *** reversed by: xDvl1(del(228-250)) [substitution] 
    *** source: 12556519-Fig-8a
  *** xAxin1[tAb] copptby[WB] xFbxw2[tAb] is undetectable
    *** cells: HEK293T<xFbxw2><xAxin1> in BMS
    *** source: 10228155-Fig-2b
  *** xAxin1[tAb] copptby[WB] xFbxw2[tAb] is undetectable
    *** cells: HEK293T<xFbxw2><xAxin1> in BMS
    *** source: 10228155-Fig-3b
  *** xAxin1[tAb] copptby[WB] xFbxw2[tAb] is undetectable
    *** cells: HEK293T<xFbxw2><xAxin1><xCtnnb1> in BMS
    *** source: 10228155-Fig-2c
  *** xAxin1[tAb] copptby[WB] xLrp5(1370-1615)"C2"[tAb] is detectable
    *** cells: COS7<xAxin1><xLrp5(1370-1615)> in BMS
    *** enhanced by: xGsk3b [addition]
    *** source: 11336703-Fig-3e
  *** xAxin1[tAb] copptby[WB] xLrp5(1419-1615)"C3"[tAb] is detectable
    *** cells: COS7<xAxin1><xLrp5(1419-1615)> in BMS
    *** enhanced by: xGsk3b [addition]
    *** source: 11336703-Fig-3e
  *** xAxin1[tAb] copptby[WB] xLrp5(1419-1615)"C3"[tAb] is detectable
    *** cells: COS7<xAxin1><xLrp5(1419-1615)> in BMS
    *** source: 11336703-Fig-3a
  *** xAxin1[tAb] copptby[WB] xMekk1(mnr)"C"[Ab] is detectable
    *** cells: HEK293T<xAxin1><xMekk1(mnr)"C"> in BMS
    *** inhibited by: xCsnk1e [addition]
    *** source: 11408485-Fig-3b
  *** xAxin1[tAb] copptby[WB] xMekk1(mnr)"C"[Ab] is detectable
    *** cells: HEK293T<xAxin1><xMekk1(mnr)"C"> in BMS
    *** inhibited by: xGsk3b [addition]
    *** inhibited by: xGsk3b(Y216F) [addition]
    *** unaffected by: xGsk3b(K83M) [addition]
    *** source: 11408485-Fig-2
  *** xAxin1[tAb] copptby[WB] xMekk1(mnr)"C"[tAb] is detectable
    *** cells: HEK293T<xAxin1><xMekk1(mnr)"C"> in BMS
    *** inhibited by: xCsnk1a1 [addition]
    *** unaffected by: xCsnk2a1 [addition]
    *** source: 11884395-Fig-2a
  *** xAxin1[tAb] copptby[WB] xMekk1(mnr)"C"[tAb] is detectable
    *** cells: HEK293T<xAxin1><xMekk1(mnr)"C"> in BMS
    *** partially inhibited by: xFrat1 [addition]
    *** partially inhibited by: xLrp5 [addition]
    *** partially inhibited by: xLrp6 [addition]
    *** source: 11884395-Fig-2b
  *** xAxin1[tAb] copptby[WB] xMyc[Ab] is detectable
    *** cells: HEK293<xAxin1><xMyc> in BMS
    *** enhanced by: xMyc(T58A) [substitution]
    *** enhanced by: xMyc(S62D) [substitution]
    *** source: 19131971-Fig-5b
  *** xAxin1[tAb] copptby[WB] xMyc[Ab] is detectable
    *** cells: HEK293<xAxin1><xMyc> in BMS
    *** inhibited by: xMyc(mnr)"delTAD" [substitution]
    *** source: 19131971-Fig-5a
  *** xAxin1[tAb] copptby[WB] xMyc[Ab] is detectable
    *** cells: HEK293<xAxin1><xMyc> in BMS
    *** inhibited by: xMyc(S62A) [substitution]
    *** source: 19131971-Fig-5c
  *** xAxin1[tAb] copptby[WB] xMyc[Ab] is detectable
    *** cells: HEK293<xAxin1><xMyc> in BMS
    *** source: 19131971-Fig-1d
  *** xAxin1[tAb] copptby[WB] xPpp2r2a[Ab] is detectable
    *** cells: HEK293T<xAxin1><xPpp2r2a> in BMS
    *** inhibited by: xPpp2r2a(mnr)"del1" [substitution]
    *** enhanced by: xPpp2r2a(mnr)"del2" [substitution]
    *** unaffected by: xPpp2r2a(mnr)"del3" [substitution]
    *** inhibited by: xPpp2r2a(mnr)"del4" [substitution]
    *** source: 19556239-Fig-5c
  *** xAxin1[tAb] locatedin(cellmembrane)[IHC] is increased itpo xFzd9
    *** cells: HEK293T<xAxin1> in BMS
    *** enhanced by: xDvl1 [addition]
    *** source: 12138115-Fig-7a
  *** xAxin1[tAb] locatedin(cellmembrane)[IHC] is increased itpo xFzd9
    *** cells: HEK293T<xAxin1><xDvl1> in BMS
    *** unaffected by: xFzd9(1-554)"C38" [substitution]
    *** unaffected by: xFzd9(del(58-174))"N" [substitution]
    *** source: 12138115-Fig-7b
  *** xAxin1[tAb] oligomerization[2TagPpt] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xDixdc1 [addition]
    *** source: 15262978-Fig-1c
  *** Axin1[tAb] oligomerization[2TagPpt] is detectable
    *** cells: HEK293T<xAxin1> in BMS
    *** unaffected by: xAxin1(del(210-352))"M2" [substitution]
    *** inhibited by: xAxin1(1-600)"C1" [substitution]
    *** source: 10575011-Fig-5a
  *** xAxin1[tAb] oligomerization[2TagPpt] is detectable
    *** cells: HEK293T<xAxin1> in BMS
    *** unaffected by: xCsnk1e [addition]
    *** source: 11884395-Fig-3
  *** Axin1[tAb] oligomerization[2TagPpt] is detectable
    *** cells: HEK293T<xAxin1><xMekk1> in BMS
    *** unaffected by: xAxin1(del(210-352))"M2" [substitution]
    *** source: 10575011-Fig-5a
  *** rAxin1[tAb] oligomerization[2TagPpt] is detectable
    *** cells: none
    *** source: 10330181-Fig-4a
  *** xAxin1[tAb] prot-stability[35S-pulse-chase] is detectable
    *** cells: COS<xAxin1> in BMS
    *** inhibited by: LiCl [addition]
    *** inhibited by: Okadaic-acid [addition]
    *** source: 10196136-Fig-2a
  *** xAxin1[tAb] prot-stability[35S-pulse-chase] is detectable
    *** cells: COS<xAxin1> in BMS
    *** inhibited by: xAxin1(S322A/S326A/S330A) [substitution]
    *** source: 10196136-Fig-2b
  *** xAxin1[tAb]IP phos[32Pi] is detectable
    *** cells: COS<xAxin1> in BMS
    *** source: 10196136-Fig-1a
  *** xAxin1[tAb]IP phos[WBMS] is increased by rPpm1a
    *** cells: none
    *** comment: reaction requires Mg2+
    *** comment: unaffected by addition of Okadaic-acid to reaction
    *** source: 10644691-Fig-3c
*** Axin2--
  *** Axin2-gene mRNA[RTPCR] is decreased itao Tnik [RNAi]
    *** cells: DLD1 in BMS
    *** source: 20530691-Fig-5
  *** Axin2-gene mRNA[RTPCR] is decreased itao Tnik [RNAi]
    *** cells: HCT116 in BMS
    *** source: 20530691-Fig-5
  *** Axin2-gene mRNA[RTPCR] is detectable
    *** cells: DLD1 in BMS
    *** partially reqs: Mekk1 [RNAi]
    *** source: 20128690-Fig-4b
  *** Axin2-gene mRNA[RTPCR] is increased itao Tab2 [RNAi]
    *** cells: HEK293T in BMS
    *** source: 20194509-Fig-3c
  *** Axin2-gene promo-reporter[Luc] is increased itpo xCtnnb1(mnr)"non-degradable"
    *** cells: HEK293<xTcf7l2(del(128-150))> in BMS
    *** enhanced by: xPias4 [addition]
    *** inhibited by: xPias4(C342A/C347A) [substitution]
    *** source: 12727872-Fig-7f
  *** Axin2-gene promo-reporter[Luc] is increased itpo xPias4
    *** cells: HEK293<xTcf7l2(del(128-150))> in BMS
    *** enhanced by: xCtnnb1(mnr)"non-degradable" [addition]
    *** source: 12727872-Fig-7f
  *** rAxin2(265-483)[32P] phos[32P-ATP] is increased by rGsk3b
    *** cells: none
    *** source: 9566905-Fig-6e
  *** xAxin2[Ab] copptby[WB] xApc(1711-1742)"Apc#3"[Ab] is detectable
    *** cells: NEURO2A<xAxin2><xApc(1711-1742)> in BMS
    *** unaffected by: xCtnnb1 [addition]
    *** source: 9554852-Fig-2b
  *** xAxin2[tAb] copptby[WB] xApc(1562-1593)"Apc#3"[Ab] is detectable
    *** cells: NEURO2A<xAxin2><xCtnnb1> in BMS
    *** source: 9554852-Fig-2a
  *** xAxin2[tAb]IP phos[32P-ATP] is increased by rGsk3b
    *** cells: none
    *** IPfrom: COS<xAxin2> in BMS
    *** source: 9566905-Fig-4a
*** Azi2--
  *** Azi2[Ab] copptby[WB] Tbk1[Ab] is detectable
    *** cells: HELA in BMS
    *** source: 14560022-Fig-3a
  *** xAzi2[tAb] copptby[WB] xTbk1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 14560022-Fig-4c
*** Bad--
  *** xBad[GST]IP phos(S99)[phosAb] is detectable
    *** cells: HEK293T in BMS
    *** reqs: Smad3 [RNAi]
    *** reqs: Smad7 [RNAi]
    *** source: 17327236-Fig-4b
  *** xBad[GST]IP phos(S99)[phosAb] is increased itpo xPdpk1
    *** cells: HEK293T in BMS
    *** source: 17327236-Fig-4c
  *** xBad[GST]IP phos(S99)[phosAb] is increased itpo xSmad2
    *** cells: HEK293T<xPdpk1> in BMS
    *** source: 17327236-Fig-4c
  *** xBad[GST]IP phos(S99)[phosAb] is increased itpo xSmad3
    *** cells: HEK293T<xPdpk1> in BMS
    *** source: 17327236-Fig-4c
  *** xBad[GST]IP phos(S99)[phosAb] is increased itpo xSmad7
    *** cells: HEK293T<xPdpk1> in BMS
    *** source: 17327236-Fig-4c
  *** rBad[phosAb] phos(S75)[phosAb] is increased by rJnk1{act}
    *** cells: none
    *** source: 11983683-Fig-4a
  *** rBad[phosAb] phos(S75)[phosAb] is increased by rMsk1{act}
    *** cells: none
    *** source: 11983683-Fig-4e
  *** rBad[phosAb] phos(S75)[phosAb] is unchanged by rErk1{act}
    *** cells: none
    *** source: 11983683-Fig-4a
  *** rBad[phosAb] phos(S75)[phosAb] is unchanged by rErk2{act}
    *** cells: none
    *** source: 11983683-Fig-4a
  *** rBad[phosAb] phos(S75)[phosAb] is unchanged by rJnk2{act}
    *** cells: none
    *** source: 11983683-Fig-4a
  *** rBad[phosAb] phos(S75)[phosAb] is unchanged by rMapkapk2{act}
    *** cells: none
    *** source: 11983683-Fig-4e
  *** rBad[phosAb] phos(S75)[phosAb] is unchanged by rP38a{act}
    *** cells: none
    *** source: 11983683-Fig-4a
*** Bag1--
  *** Bag1[Ab] copptby[WB] Araf[Ab] is undetectable
    *** cells: PC12 in BMS
    *** source: 16116448-Fig-7b
  *** Bag1[Ab] copptby[WB] Raf1[Ab] is detectable
    *** cells: PC12 in BMS
    *** source: 16116448-Fig-7b
  *** rBag1[tAb] boundby[WB] rRaf1[GST] is detectable
    *** cells: none
    *** inhibited by: rHsp70 [addition]
    *** source: 11231577-Fig-2a
  *** Bag4[Ab] copptby[WB] TnfR1[Ab] is detectable
    *** cells: U937 in BMS
    *** source: 9915703-Fig-4a
  *** xBag4[tAb] copptby[WB] xTnfR1[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 9915703-Fig-2b
*** Bax--
  *** Bax-gene mRNA[RTPCR] is decreased itao Setd7 [RNAi]
    *** cells: U2OS in BMS
    *** source: 15525938-Fig-S3
  *** Bax-gene mRNA[RTPCR] is detectable
    *** cells: mEFs in BMS
    *** reqs: Egr1 [KO]
    *** source: 15958557-Fig-1
  *** Bax-gene mRNA[RTPCR] is detectable
    *** cells: mThyCs in BMS "treated with IR for 18 hr"
    *** inhibited by: kTp53(S18A) [knockin] 
    *** inhibited by: kTp53(S18A/S23A) [knockin] 
    *** reqs: Tp53 [KO]
    *** source: 16757976-Fig-4b
  *** Bax-gene mRNA[RTPCR] is increased itpo xSetd7
    *** cells: U2OS in BMS
    *** source: 15525938-Fig-S3
  *** Bax-gene promo-reporter[Luc] is increased itpo xHipk2
    *** cells: MCF7 in BMS
    *** inhibited by: xHipk2(1-864) [substitution]
    *** source: 11780126-Fig-6e
  *** Bax[Ab] prot-exp[WB] is increased itao Huwe1 [RNAi]
    *** cells: U2OS in BMS
    *** source: 15989956-Fig-5a
  *** Bax[Ab] prot-exp[WB] is increased itao Huwe1 [RNAi]
    *** cells: U2OS in BMS
    *** source: 15989956-Fig-8a
  *** Bax[Ab] prot-exp[WB] is increased itao Huwe1 [RNAi]
    *** cells: U2OS in BMS
    *** source: 15989956-Fig-S4d
  *** Bax[Ab] prot-exp[WB] is increased itao Mdm2 [RNAi]
    *** cells: U2OS in BMS
    *** source: 15989956-Fig-8a
  *** Bax[Ab] prot-exp[WB] is increased itao Pirh2 [RNAi]
    *** cells: U2OS in BMS
    *** source: 15989956-Fig-8a
  *** Bax[Ab] prot-exp[WB] is increased itpo xCdk5
    *** cells: SHSY5Y in BMS
    *** source: 12064478-Fig-3
  *** Bax[Ab] prot-exp[WB] is increased itpo xCdk5r1{p25}
    *** cells: SHSY5Y in BMS
    *** source: 12064478-Fig-3
  *** Bax[Ab] prot-exp[WB] is increased itpo xP14Arf
    *** cells: U2OS in BMS
    *** source: 15989956-Fig-S13
  *** Bax[Ab] prot-exp[WB] is unchanged itao Cop1 [RNAi]
    *** cells: U2OS in BMS
    *** source: 15989956-Fig-8a
*** Bbc3--
  *** Bbc3-gene mRNA[RTPCR] is detectable
    *** cells: mThyCs in BMS "treated with IR for 18 hr"
    *** inhibited by: kTp53(S18A) [knockin] 
    *** inhibited by: kTp53(S18A/S23A) [knockin] 
    *** reqs: Tp53 [KO]
    *** source: 16757976-Fig-4b
*** Bcar1--
  *** rBcar1(213-514)"SD"[GST] Yphos[pYAb] is increased by xFak2[tAb]IP
    *** cells: none
    *** IPfrom: COS7<xFak2> in BMS
    *** unaffected by: xFak2(Y402F) [substitution]
    *** inhibited by: xFak2(K457R) [substitution]
    *** source: 9242628-Fig-5
  *** rBcar1(691-786)"SB"[GST] Yphos[pYAb] is increased by xFak2[tAb]IP
    *** cells: none
    *** IPfrom: COS7<xFak2> in BMS
    *** partially inhibited by: xFak2(Y402F) [substitution]
    *** inhibited by: xFak2(K457R) [substitution]
    *** source: 9242628-Fig-6
  *** Bcar1[Ab] copptby[WB] Crk[Ab] is increased itpo xSh2d3c(myr)
    *** cells: HEK293 in BMS
    *** inhibited by: xSh2d3c(myr/Y635E) [substitution]
    *** source: 15272013-Fig-7a
  *** Bcar1[Ab] copptby[WB] xFes[Ab] is detectable
    *** cells: BAC12F5<xFes> in BMS
    *** source: 8999909-Fig-2
  *** Bcar1[Ab] copptby[WB] xPtprh(D988A)"CIA"[tAb] is detectable
    *** cells: PANC1<xPtprh(D988A)"CIA"> in BMS "treated with pervanadate for 30 min"
    *** inhibited by: xPtprh(C1022S)"CIA" [substitution]
    *** inhibited by: xPtprh [substitution]
    *** source: 11278335-Fig-1d
  *** Bcar1[Ab] copptby[WB] xTrip6[tAb] is detectable
    *** cells: HEK293T<xCrkI><xTrip6><xSrc> in BMLS
    *** reqs: xCrkI [omission]
    *** source: 15988003-Fig-4b
  *** Bcar1[Ab] Yphos[pYAb-ppt] is increased itpo xFak2
    *** cells: HEK293T in BMS
    *** inhibited by: xFak2(Y402F) [substitution]
    *** unaffected by: xFak2(Y881F) [substitution]
    *** inhibited by: xFak2(mnr)"KD" [substitution]
    *** source: 10329689-Fig-5a
  *** Bcar1[Ab] Yphos[pYAb-ppt] is increased itpo xFak2
    *** cells: HEK293T in BMS
    *** partially inhibited by: xSrc(mnr)"KD" [addition]
    *** source: 10329689-Fig-5a
  *** Bcar1[Ab]IP Yphos[pYAb] is detectable
    *** cells: HELA in BMLS
    *** unaffected by: xSrc(mnr)"vSrc" [addition]
    *** source: 10618718-Fig-2b
  *** Bcar1[Ab]IP Yphos[pYAb] is detectable
    *** cells: MDAMB468 in BMLS
    *** source: 15140944-Fig-5b
  *** xBcar1[Ab]IP Yphos[pYAb] is increased itpo xFak2
    *** cells: COS7<xBcar1> in BMS
    *** partially inhibited by: xFak2(Y402F) [substitution]
    *** inhibited by: xFak2(K457R) [substitution]
    *** source: 9242628-Fig-3b
  *** xBcar1[Ab]IP Yphos[pYAb] is increased itpo xFak2
    *** cells: COS7<xBcar1> in BMS
    *** partially inhibited by: xFak2(Y402F) [substitution]
    *** inhibited by: xFak2(K457R) [substitution]
    *** source: 9242628-Fig-7a
  *** Bcar1[Ab]IP Yphos[pYAb] is increased itpo xSh2d3c(myr)
    *** cells: COS in BMS
    *** inhibited by: xSh2d3c(myr/Y635E) [substitution]
    *** source: 15272013-Fig-6b
  *** Bcar1[Ab]IP Yphos[pYAb] is increased itpo xSh2d3c(myr)
    *** cells: HEK293 in BMS
    *** inhibited by: xSrc(mnr)"DN" [addition]
    *** source: 15272013-Fig-6c
  *** xBcar1[tAb]IP Yphos[pYAb] is decreased itpo xPtprh
    *** cells: HEK293 in BMS
    *** reversed by: rPtprh(C1022S)"CIA" [substitution]
    *** reversed by: rPtprh(D988A)"CIA" [substitution]
    *** source: 11278335-Fig-3a
  *** xBcar1[tAb]IP Yphos[pYAb] is increased itpo xFak2
    *** cells: COS7<xBcar1> in BMS
    *** source: 9242628-Fig-2c
  *** xBcar1[tAb]IP Yphos[pYAb] is increased itpo xFyn
    *** cells: COS7<xBcar1> in BMS
    *** source: 9188452-Fig-3a
*** Bcl2--
  *** Bcl2-gene mRNA[Northern] is detectable
    *** cells: mSpCs in BMS "treated with anti-Cd3 for 48 hr"
    *** does not req: Stat6 [KO]
    *** source: 10843732-Fig-5
  *** Bcl2-gene mRNA[RTPCR] is detectable
    *** cells: THP1 in BMS
    *** reqs: Ampka1 [RNAi]
    *** source: 22833096-Fig-4d
  *** Bcl2-gene promo-reporter[Luc] is increased itpo xIkzf3
    *** cells: TS1<xIL2Ra><xIL2Rb> in BMS "containing IL2"
    *** source: 10369681-Fig-6a
  *** xBcl2[Ab] copptby[WB] Becn1[Ab] is detectable
    *** cells: HT29 in BMS
    *** source: 16179260(D)
  *** Bcl2[Ab] copptby[WB] Becn1[Ab] is undetectable
    *** cells: U251 in BMS
    *** source: 16390869(D)
  *** xBcl2[Ab] copptby[WB] xBecn1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xBcl2(G145A) [substitution]
    *** inhibited by: xBcl2(W188A) [substitution]
    *** inhibited by: xBecn1(F1232A) [substitution]
    *** unaffected by: xBecn1(I125A) [substitution]
    *** inhibited by: xBecn1(mnr)"Bcl2-BD-mut" [substitution]
    *** source: 16179260(D)
  *** Bcl2[Ab] prot-exp[WB] is detectable
    *** cells: mLCs<IgM~neg><IgG~neg> in BMS
    *** reqs: Irs2 [KO]
    *** reqs: Stat6 [KO]
    *** source: 11739727-Fig-5b
  *** Bcl2[Ab] prot-exp[WB] is detectable
    *** cells: mLCs<IgM~neg><IgG~neg> in BMS "treated with IL4 for 17 hr"
    *** reqs: Irs2 [KO]
    *** does not req: Stat6 [KO]
    *** source: 11739727-Fig-5b
  *** Bcl2[Ab] prot-exp[WB] is detectable
    *** cells: TS1<xIL2Ra><xIL2Rb> in BMS "containing IL2"
    *** source: 10369681-Fig-8
  *** Bcl2[Ab] prot-exp[WB] is undetectable
    *** cells: TS1<xIL2Ra><xIL2Rb> in BMS "containing IL4"
    *** source: 10369681-Fig-8
*** Bcl3--
  *** Bcl3-gene mRNA[RTPCR] is detectable
    *** cells: THP1 in BMS
    *** reqs: Ampka1 [RNAi]
    *** source: 22833096-Fig-4d
  *** Bcl3[Ab] snaggedby[WB] rBcl10[GST] is detectable
    *** cells: MCF7 in BMS "treated with Tnf for (1 hr)"
    *** enhanced by: rBcl10(S218D) [substitution]
    *** enhanced by: rBcl10(S231D) [substitution]
    *** enhanced by: rBcl10(1-206) [substitution]
    *** source: 16280327-Fig-7e
  *** rBcl6[Ab] oligo-binding[EMSA] is detectable
    *** cells: none
    *** oligo: "Cd23b-GAS" 5-GATCAGGGTGAATTTCTAAGAAAGGGACTGGTGT-3
    *** source: 9110977-Fig-5a
*** Bcl10--
  *** rBcl10[32P] phos[32P-ATP] is increased by Akt1[Ab]IP
    *** cells: none
    *** IPfrom: MCF7 in BMS "treated with Tnf (30 min)"
    *** inhibited by: rBcl10(S218A/S231A) [substitution]
    *** source: 16280327-Fig-6b
  *** Bcl10[Ab] copptby[WB] Bcl3[Ab] is detectable
    *** cells: MCF7 in BMS
    *** source: 16280327-Fig-7c
  *** Bcl10[Ab] copptby[WB] Rela[Ab] is undetectable
    *** cells: MCF7 in BMS
    *** source: 16280327-Fig-7d
  *** rBcl10[Ab] oligomerization[density-gradient] is increased by rIrak1
    *** cells: none
    *** inhibited by: rIrak1(T66E)"oligomerization-mut" [substitution]
    *** source: 16831874-Fig-7a
  *** rBcl10[Ab] oligomerization[density-gradient] is increased by rIrak1b
    *** cells: none
    *** source: 16831874-Fig-7a
  *** xBcl10[tAb] copptby[WB] xNod1[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 10329646(D)
*** Bclxl--
  *** Bclxl-gene mRNA[Northern] is detectable
    *** cells: mSpCs in BMS "treated with anti-Cd3 for 48 hr"
    *** does not req: Stat6 [KO]
    *** source: 10843732-Fig-5
  *** Bclxl-gene mRNA[RTPCR] is increased itpo xMitf
    *** cells: B16 in BMS
    *** inhibited by: xMitf(S409D) [substitution]
    *** source: 15572665-Fig-7c
  *** Bclxl-gene mRNA[RTPCR] is increased itpo xStat3(C661A/C663N)
    *** cells: B16 in BMS
    *** source: 15572665-Fig-7d
  *** Bclxl[Ab] copptby[WB] Becn1[Ab] is undetectable
    *** cells: U251 in BMS
    *** source: 16390869(D)
  *** Bdnf[125I] receptor-binding[RIA] is detectable
    *** cells: NIH3T3<xTrkb> in BMS
    *** source: 1375038-Fig-1b
*** Becn1--
  *** Becn1[Ab] copptby[WB] Bcl2[Ab] is undetectable
    *** cells: U251 in BMS
    *** source: 16390869(D)
  *** Becn1[Ab] copptby[WB] xBclxl[tAb] is detectable
    *** cells: HELA in BMS
    *** inhibited by: xBclxl(G138A) [substitution]
    *** source: 17446862(D)
  *** xBecn1[Ab] copptby[WB] xBclxl[tAb] is detectable
    *** cells: HELA in BMS
    *** inhibited by: xBecn1(L116A) [substitution]
    *** unaffected by: xBecn1(F123A) [substitution]
    *** source: 17446862(D)
  *** xBecn1[tAb]IP IVLKA(PtdIns)[TLC] is detectable
    *** cells: MCF7<Becn1~null><xBecn1> in BMS
    *** inhibited by: xBecn1(del(244-337)) [substitution]
    *** source: 16874027(D)
*** Bmp2--
  *** rBmp2[125I] copptby[Xlink] AcvR1b[Ab] is undetectable
    *** cells: P19 in BMS
    *** source: 9748228(D)
*** Bmp7--
  *** rBmp7[125I] copptby[Xlink] AcvR1b[Ab] is undetectable
    *** cells: P19 in BMS
    *** source: 9748228(D)
  *** rBmp7[125I] copptby[Xlink] xSmad2[tAb] is undetectable
    *** cells: COS1<xAcvR1><xAcvR2b> in BMS
    *** source: 9748228(D)
*** BmpR1a--
  *** xBmpR1a(mnr)"KD"[tAb] copptby[WB] xSnx1[tAb] is undetectable
    *** cells: COS1 in BMLS
    *** source: 11279102(D)
  *** xBmpR1a(mnr)"KD"[tAb] copptby[WB] xSnx2[tAb] is undetectable
    *** cells: COS1 in BMLS
    *** source: 11279102(D)
  *** xBmpR1a(mnr)"KD"[tAb] copptby[WB] xSnx3[tAb] is undetectable
    *** cells: COS1 in BMLS
    *** source: 11279102(D)
  *** xBmpR1a(mnr)"KD"[tAb] copptby[WB] xSnx4[tAb] is undetectable
    *** cells: COS1 in BMLS
    *** source: 11279102(D)
  *** xBmpR1a(mnr)"KD"[tAb] copptby[WB] xSnx6[tAb] is undetectable
    *** cells: COS1 in BMLS
    *** source: 11279102(D)
  *** xBmpR1a[tAb] copptby[WB] xAmhR2[Ab] is undetectable
    *** cells: CHO in BMS
    *** unaffected by: Amh (45 min) [stim]
    *** source: 10854429(D)
  *** xBmpR1a[tAb] copptby[WB] xZfyve16[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 17272273-Fig-4d
  *** xBmpR1a[tAb]IP cleavage[WB] is unchanged itpo xAdam17
    *** cells: CHO<xBmpR1a> in BMLS
    *** source: 19595713-Fig-3d
*** BmpR1b--
  *** xBmpR1b(mnr)"KD"[tAb] copptby[WB] xSnx1[tAb] is undetectable
    *** cells: COS1 in BMLS
    *** source: 11279102(D)
  *** xBmpR1b(mnr)"KD"[tAb] copptby[WB] xSnx2[tAb] is undetectable
    *** cells: COS1 in BMLS
    *** source: 11279102(D)
  *** xBmpR1b(mnr)"KD"[tAb] copptby[WB] xSnx3[tAb] is undetectable
    *** cells: COS1 in BMLS
    *** source: 11279102(D)
  *** xBmpR1b(mnr)"KD"[tAb] copptby[WB] xSnx4[tAb] is detectable
    *** cells: COS1 in BMLS
    *** source: 11279102(D)
  *** xBmpR1b(mnr)"KD"[tAb] copptby[WB] xSnx6[tAb] is detectable
    *** cells: COS1 in BMLS
    *** source: 11279102(D)
  *** xBmpR1b[tAb] copptby[WB] xZfyve16[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 17272273-Fig-4d
  *** xBmpR1b[tAb]IP cleavage[WB] is unchanged itpo xAdam17
    *** cells: CHO<xBmpR1b> in BMLS
    *** source: 19595713-Fig-3d
*** BmpR2--
  *** xBmpR2[125I] boundby[Xlink] rInhba[125I] is undetectable
    *** cells: COS1 in BMS
    *** unaffected by: xAcvR1b [addition]
    *** source: 7791754(D)
  *** xBmpR2[125I] boundby[Xlink] rTgfb1[125I] is undetectable
    *** cells: COS1 in BMS
    *** unaffected by: xTgfbR1 [addition]
    *** source: 7791754(D)
  *** xBmpR2[tAb] copptby[WB] xSnx6[tAb] is undetectable
    *** cells: COS1 in BMLS
    *** source: 11279102(D)
  *** xBmpR2[tAb]IP IVKA(Smad1)[32P-ATP] is increased itpo xAcvR1
    *** cells: COS1<xBmpR2> in BMS "treated with Bmp7 (30 min)"
    *** source: 9748228(D)
*** Braf--
  *** xBraf(1-436)[tAb] copptby[WB] xBraf(437-766)[tAb] is decreased itpo xHras(G12V)
    *** cells: HEK293<xBraf(1-436)><xBraf(437-766)> in BMLS
    *** enhanced by: xBraf(437-766/T599E/S602D) [substitution]
    *** unaffected by: xBraf(437-766/T599A/S602A) [substitution]
    *** source: 15710605-Fig-8b
  *** xBraf(1-436)[tAb] copptby[WB] xBraf(437-766)[tAb] is decreased itpo xHras(G12V)
    *** cells: HEK293<xBraf(1-436)><xBraf(437-766)> in BMLS
    *** reversed by: xBraf(1-436/R188L) [substitution]
    *** source: 15710605-Fig-6a
  *** xBraf(1-436)[tAb] copptby[WB] xBraf(437-766)[tAb] is decreased itpo xHras(G12V)
    *** cells: HEK293<xBraf(1-436)><xBraf(437-766)> in BMLS
    *** unaffected by: xBraf(437-766/S446A) [substitution]
    *** source: 15710605-Fig-6b
  *** xBraf(1-436)[tAb] copptby[WB] xBraf(437-766)[tAb] is detectable
    *** cells: HEK293<xBraf(1-436)><xBraf(437-766)> in BMLS
    *** unaffected by: xBraf(1-375) [substitution]
    *** inhibited by: xBraf(1-282) [substitution]
    *** unaffected by: xBraf(101-346) [substitution]
    *** source: 15710605-Fig-4
  *** xBraf(416-766)[tAb]IP IVKA(Mek1,Erk2)[32P-ATP] is detectable
    *** cells: HEK293<xBraf(S365A)> in BMS
    *** inhibited by: xBraf [substitution]
    *** source: 16702958-Fig-4a
  *** xBraf(437-766)[tAb]IP phos(S446)[phosAb] is increased itpo xPak1(L107F)"CA"
    *** cells: HEK293<xBraf(437-766)> in BMLS
    *** source: 15710605-Fig-7d
  *** Braf(D594G)"CA"[Ab]IP phos[32Pi] is detectable
    *** cells: NIH3T3 in BMLS
    *** comment: phos sites were shown to be S151 T401 S750 T753 by HPLC
    *** source: 19933846-Fig-2a
  *** Braf(G455A)"CA"[Ab]IP phos[32Pi] is detectable
    *** cells: NIH3T3 in BMLS
    *** comment: phos sites were shown to be S151 T401 S750 T753 by HPLC
    *** source: 19933846-Fig-2a
  *** xBraf(G466A)[tAb] copptby[WB] Raf1[Ab] is detectable
    *** cells: NIH3T3<xBraf(G466A)> in BMS
    *** enhanced by: xBraf(G466A/S151A) [substitution]
    *** unaffected by: xBraf(G466A/T401A) [substitution]
    *** enhanced by: xBraf(G466A/S750A/T753A) [substitution]
    *** enhanced by: xBraf(G466A/S151A/S401A/S750A/T753A) [substitution]
    *** inhibited by: xBraf(G466A/S151A/S401A/S750A/T753A/S729A) [substitution]
    *** source: 19933846-Fig-6a
  *** xBraf(G466A)[tAb] snaggedby[WB] Hras(G12V)[GST] is detectable
    *** cells: NIH3T3<xBraf(G466A)> in BMS
    *** enhanced by: xBraf(G466A/S151A) [substitution]
    *** unaffected by: xBraf(G466A/T401A) [substitution]
    *** unaffected by: xBraf(G466A/S750A/T753A) [substitution]
    *** enhanced by: xBraf(G466A/S151A/S401A/S750A/T753A) [substitution]
    *** enhanced by: xBraf(G466A/S151A/S401A/S750A/T753A/S729A) [substitution]
    *** source: 19933846-Fig-6a
  *** xBraf(K428M)[tAb]IP phos[32P-ATP] is increased by xAkt1{act}[tAb]IP
    *** cells: none
    *** IP1from: HEK293 in BMS
    *** IP2from: HEK293 in BMLS "treated with Ins for 10 min"
    *** partially inhibited by: xBraf(K428M/S428A/T439A) [substitution]
    *** inhibited by: xBraf(K428M/S364A/S428A/T439A) [substitution]
    *** partially inhibited by: xBraf(K428M/S364A) [substitution]
    *** partially inhibited by: xBraf(K428M/S428A) [substitution]
    *** unaffected by: xBraf(K428M/T439A) [substitution]
    *** source: 10869359-Fig-6
  *** xBraf(mnr)"KD"[tAb]IP phos[32P-ATP] is increased by rErk2{act}
    *** cells: none
    *** IPfrom: NIH3T3<xBraf(mnr)"KD"> in BMLS
    *** comment: phos sites were shown to be S151 S401 S750 T753 by HPLC
    *** source: 19933846-Fig-2b
  *** xBraf(S151A)[tAb] copptby[WB] Raf1[Ab] is detectable
    *** cells: NIH3T3<xBraf(S151A)> in BMS "treated with Pdgf for 30 min"
    *** inhibited by: xBraf [substitution]
    *** inhibited by: xBraf(T401A) [substitution]
    *** inhibited by: xBraf(S750A/T753A) [substitution]
    *** enhanced by: xBraf(S151A/S401A/S750A/T753A) [substitution]
    *** inhibited by: xBraf(S151A/S401A/S750A/T753A/S729A) [substitution]
    *** source: 19933846-Fig-6a
  *** xBraf(S151A)[tAb] snaggedby[WB] Hras(G12V)[GST] is detectable
    *** cells: NIH3T3<xBraf(S151A)> in BMS "treated with Pdgf for 30 min"
    *** inhibited by: xBraf [substitution]
    *** inhibited by: xBraf(T401A) [substitution]
    *** inhibited by: xBraf(S750A/T753A) [substitution]
    *** unaffected by: xBraf(S151A/S401A/S750A/T753A) [substitution]
    *** unaffected by: xBraf(S151A/S401A/S750A/T753A/S729A) [substitution]
    *** source: 19933846-Fig-6a
  *** xBraf(S365A)[tAb]IP IVKA(Mek1,Erk2)[32P-ATP] is detectable
    *** cells: HEK293<xBraf(S365A)> in BMS
    *** unaffected by: xBraf(S365A/S446A/S447A) [substitution]
    *** inhibited by: xBraf(S365A/S365A/S446A/S447A/D448A/D449A) [substitution]
    *** source: 16702958-Fig-4a
  *** xBraf(S446D)[tAb]IP IVKA(Mek1)[32P-ATP] is decreased itpo xRheb
    *** cells: HEK293 in BMLS
    *** source: 16803888-Fig-3e
  *** xBraf(T599E/S602D)[tAb]IP IVKA(Mek1)[32P-ATP] is unchanged itpo xRheb
    *** cells: HEK293 in BMLS
    *** source: 16803888-Fig-3e
  *** Braf(V600E)"CA"[Ab]IP phos[32Pi] is detectable
    *** cells: NIH3T3 in BMLS
    *** comment: phos sites were shown to be S151 T401 S750 T753 by HPLC
    *** source: 19933846-Fig-2a
  *** xBraf(V600E)[tAb] copptby[WB] Raf1[Ab] is decreased itpo xRheb
    *** cells: HEK293 in BMLS
    *** source: 16803888-Fig-2d
  *** xBraf(V600E)[tAb]IP IVKA(Mek1,Erk2)[32P-ATP] is detectable
    *** cells: HEK293<xBraf(V600E)> in BMS
    *** inhibited by: xBraf [substitution]
    *** inhibited by: xBraf(V600E/S365A/S446A/S447A/D448A/D449A) [substitution]
    *** unaffected by: xBraf(S365A) [substitution]
    *** unaffected by: xBraf(416-766) [substitution]
    *** source: 16702958-Fig-4b
  *** xBraf(V600E)[tAb]IP IVKA(Mek1,Erk2)[32P-ATP] is detectable
    *** cells: HEK293<xBraf(V600E)> in BMS
    *** unaffected by: xBraf(V600E/R188L) [substitution]
    *** unaffected by: xBraf(V600E/S446A/S447A) [substitution]
    *** inhibited by: xBraf(V600E/S365A/S446A/S447A/D448A/D449A) [substitution]
    *** source: 16702958-Fig-4a
  *** xBraf(V600E)[tAb]IP IVKA(Mek1)[32P-ATP] is unchanged itpo xRheb
    *** cells: HEK293 in BMLS
    *** source: 16803888-Fig-3d
  *** xBraf(V600E)[tAb]IP phos(S446)[phosAb] is decreased itpo xRheb
    *** cells: HEK293 in BMLS
    *** source: 16803888-Fig-3c
  *** xBraf[Ab] copptby[WB] Raf1[Ab] is decreased itpo xBrap
    *** cells: HEK293<xBraf> in BMS
    *** source: 18332145-Fig-2b
  *** xBraf[Ab] copptby[WB] Raf1[Ab] is detectable
    *** cells: HEK293<xBraf> in BMS
    *** unaffected by: xBraf(G596R) [substitution]
    *** source: 18332145-Fig-2b
  *** Braf[Ab] copptby[WB] xBrap[tAb] is detectable
    *** cells: HEK293<xKsr1><xBrap> in BMS
    *** source: 18332145-Fig-1b
  *** Braf[Ab] copptby[WB] xKsr1[Ab] is detectable
    *** cells: HEK293<xKsr1> in BMS
    *** unaffected by: xKsr1(540-873)"mCterm" [substitution]
    *** source: 18332145-Fig-1a
  *** Braf[Ab] copptby[WB] xKsr1[tAb] is detectable
    *** cells: HEK293<xKsr1> in BMS
    *** unaffected by: xBrap [addition]
    *** source: 18332145-Fig-1a
  *** Braf[Ab] copptby[WB] xKsr1[tAb] is detectable
    *** cells: mEFs<Ksr1~null><xKsr1><xMek1> in BMLS
    *** enhanced by: xKsr1(mnr)"AxAp" [substitution]
    *** source: 19541618-Fig-3b
  *** Braf[Ab] copptby[WB] xKsr1[tAb] is detectable
    *** cells: mEFs<Ksr1~null><xKsr1><xMek1> in BMLS
    *** inhibited by: xKsr1(530-873)"mouseCterm" [substitution]
    *** inhibited by: xKsr1(1-529)"mouseNterm" [substitution]
    *** inhibited by: xKsr1(L58G/R57S) [substitution]
    *** enhanced by: xKsr1(mnr)"AxAp" [substitution]
    *** inhibited by: xKsr1(C857Y) [substitution]
    *** source: 19541618-Fig-3a
  *** Braf[Ab] copptby[WB] xMek1[tAb] is detectable
    *** cells: mEFs<Ksr1~null><xKsr1><xMek1> in BMS
    *** inhibited by: xMek1(del(270-307))"dPRS" [substitution]
    *** unaffected by: xMek1(L274S) [substitution]
    *** unaffected by: xMek1(F275A) [substitution]
    *** unaffected by: xMek1(D303A) [substitution]
    *** inhibited by: xMek1(M308A/I310A) [substitution]
    *** source: 19541618-Fig-1c
  *** Braf[Ab] copptby[WB] xMek1[tAb] is detectable
    *** cells: mEFs<Ksr1~null><xMek1> in BMS
    *** inhibited by: xMek1(M308A/I310A) [substitution]
    *** source: 19541618-Fig-S1a
  *** Braf[Ab] copptby[WB] xMek1[tAb] is detectable
    *** cells: mEFs<Ksr1~null><xMek1> in BMS
    *** unaffected by: xKsr1 [addition]
    *** unaffected by: xKsr1(C809Y)"hC857Y" [addition]
    *** source: 19541618-Fig-S1a
  *** Braf[Ab] copptby[WB] xMek2[tAb] is detectable
    *** cells: mEFs<Ksr1~null><xKsr1><xMek2> in BMS
    *** inhibited by: xMek2(M316A/I318A) [substitution]
    *** source: 19541618-Fig-1c
  *** Braf[Ab] copptby[WB] xMek2[tAb] is detectable
    *** cells: mEFs<Ksr1~null><xMek2> in BMS
    *** inhibited by: xMek2(M316A/I318A) [substitution]
    *** source: 19541618-Fig-S1a
  *** Braf[Ab] copptby[WB] xMek2[tAb] is detectable
    *** cells: mEFs<Ksr1~null><xMek2> in BMS
    *** unaffected by: xKsr1 [addition]
    *** unaffected by: xKsr1(C809Y)"hC857Y" [addition]
    *** source: 19541618-Fig-S1a
  *** Braf[Ab] copptby[WB] xRaf1(T260A/T274A/S320A/S443A)[tAb] is detectable
    *** cells: NIH3T3<xRaf1(T260A/T274A/S320A/S443A)> in BMLS
    *** inhibited by: xRaf1 [substitution]
    *** enhanced by: xRaf1(P261S/T260A/T274A/S320A/S443A) [substitution]
    *** enhanced by: xRaf1(L613V/T260A/T274A/S320A/S443A) [substitution]
    *** source: 19933846-Fig-8a
  *** Braf[Ab] copptby[WB] xRaf1[Ab] is unchanged itpo xHras(G12V)"CA"
    *** cells: HEK293 in BMLS
    *** comment: no evidence that Braf is detectable in this experiment
    *** source: 11325826-Fig-1d
  *** xBraf[Ab] copptby[WB] xRaf1[tAb] is detectable
    *** cells: HEK293 in BMLS
    *** inhibited by: xRaf1(S621A) [substitution]
    *** source: 11325826-Fig-3
  *** xBraf[Ab] copptby[WB] xRaf1[tAb] is increased itpo xHras(G12V)"CA"
    *** cells: HEK293 in BMLS
    *** source: 11325826-Fig-1b
  *** xBraf[Ab] copptby[WB] xRaf1[tAb] is increased itpo xHras(G12V)"CA"
    *** cells: HEK293 in BMLS
    *** unaffected by: xRaf1(S259A) [substitution]
    *** bkg inhibited by: xRaf1(S621A) [substitution]
    *** source: 11325826-Fig-3
  *** Braf[Ab] copptby[WB] xRap1a(G12V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 16630891-Fig-1b
  *** xBraf[Ab] copptby[WB] xRap1a[tAb] is detectable
    *** cells: PC12 in BMLS
    *** enhanced by: xRapGef1 [addition]
    *** inhibited by: xCrkL [addition]
    *** source: 9560161-Fig-4e
  *** xBraf[Ab] copptby[WB] xRap1a[tAb] is detectable
    *** cells: PC12 in BMLS
    *** unaffected by: xPkca [addition]
    *** source: 9094716-Fig-6d
  *** xBraf[Ab] copptby[WB] xRap1a[tAb] is detectable
    *** cells: PC12 in BMLS
    *** unaffected by: xRap1a(G12V)"CA" [substitution]
    *** source: 9094716-Fig-6d
  *** Braf[Ab] copptby[WB] xRit1(Q79L)"CA"[tAb] is detectable
    *** cells: COS in BMS
    *** unaffected by: xRit1(WT) [substitution]
    *** source: 15632082-Fig-3c
  *** Braf[Ab] copptby[WB] xRras(G38V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xRras [substitution]
    *** source: 16630891-Fig-1b
  *** Braf[Ab]IP IVKA(Mek1,Erk?,MBP)[32P-ATP] is increased itao Raf1 [KO]
    *** cells: mEFs in BMLS
    *** source: 11296228-Fig-6c
  *** Braf[Ab]IP IVKA(Mek1)[32P-ATP] is detectable
    *** cells: HEK293 in BMLS
    *** reqs: Tsc2 [RNAi]
    *** source: 16803888-Fig-3a
  *** Braf[Ab]IP IVKA(Mek1)[32P-ATP] is detectable
    *** cells: mEFs in BMLS
    *** reqs: Tsc2 [KO]
    *** source: 16803888-Fig-4a
  *** xBraf[Ab]IP IVKA(Mek1)[32P-ATP] is increased itpo xRapGef1
    *** cells: PC12<xRap1a> in BMLS
    *** enhanced by: xCrkL [addition]
    *** source: 9560161-Fig-4e
  *** xBraf[Ab]IP IVKA(Mek1)[32P-ATP] is unchanged itpo xCrkL
    *** cells: PC12<xRap1a> in BMLS
    *** source: 9560161-Fig-4e
  *** xBraf[Ab]IP IVKA(Mek1)[32P-ATP] is unchanged itpo xRap1a(G12V)"CA"
    *** cells: HEK293 in BMLS
    *** source: 11325826-Fig-2
  *** Braf[Ab]IP phos(S446)[phosAb] is detectable
    *** cells: HEK293 in BMLS
    *** reqs: Tsc2 [RNAi]
    *** source: 16803888-Fig-3a
  *** xBraf[Ab]IP phos(S446)[phosAb] is increased itpo xRit1(Q79L)"CA"
    *** cells: PC6 in BMS
    *** inhibited by: xRit1(WT) [substitution]
    *** inhibited by: xRit1(S35N) [substitution]
    *** source: 15632082-Fig-4b
  *** xBraf[Ab]IP phos(S729)[phosAb] is detectable-but unchanged itpo (xHras(G12V) + xLck)
    *** cells: SF9<xBraf> in BMS
    *** source: 14688280-Fig-2b
  *** Braf[Ab]IP STphos[pSTAb] is increased itao Pin1 [KO]
    *** cells: mEFs in BMLS
    *** source: 19933846-Fig-1f
  *** xBraf[GST]IP IVKA(Mek1,Erk2,MBP)[32P-ATP] is increased itpo xRit1(Q79L)"CA"
    *** cells: COS in BMLS
    *** partially inhibited by: xRit1(WT) [substitution]
    *** inhibited by: xRit1(S35N) [substitution]
    *** source: 15632082-Fig-4c
  *** xBraf[phosAb] phos(S365)[phosAb] is detectable-but unchanged itpo (xHras(G12V) + xLck)
    *** cells: SF9<xBraf> in BMS
    *** source: 14688280-Fig-3
  *** xBraf[phosAb] phos(S446)[phosAb] is decreased itpo xRheb
    *** cells: HEK293 in BMLS
    *** source: 16803888-Fig-3b
  *** xBraf[phosAb] phos(S729)[phosAb] is increased itpo (xHras(G12V) + xLck)
    *** cells: SF9<xBraf> in BMS
    *** comment: basal phos is high and increase is slight
    *** source: 14688280-Fig-3
  *** Braf[phosAb] phos(T599/S602)[phosAb] is decreased itpo xMerlinb
    *** cells: HEI193 in BMS
    *** source: 20890305-Fig-3b
  *** Braf[phosAb] phos(T599/S602)[phosAb] is decreased itpo xMerlinb
    *** cells: RT4 in BMS
    *** source: 20890305-Fig-3a
  *** Braf[phosAb] phos(T599/S602)[phosAb] is decreased itpo xMerlinb
    *** cells: SKOV3 in BMS
    *** source: 20890305-Fig-3b
  *** Braf[phosAb] phos(T599/S602)[phosAb] is increased itao Merlin [RNAi]
    *** cells: T29 in BMS
    *** source: 20890305-Fig-3c
  *** rBraf[tAb] boundby[WB] rRaf1[tAb] is increased by rYwhaz
    *** cells: none
    *** inhibited by: rYwhaz(E5K/L12Q/A13Q/E14R/Y82Q/K85N/E87Q)"dimerization-mut" [substitution]
    *** source: 16508002-Fig-4b
  *** xBraf[tAb] copptby[WB] Hras[Ab] is decreased itpo xRheb(Q64L)"CA"
    *** cells: HEK293 in BMLS
    *** source: 16803888-Fig-4c
  *** xBraf[tAb] copptby[WB] Raf1[Ab] is decreased itpo xRheb
    *** cells: HEK293 in BMLS
    *** reversed by: xRheb [addition]
    *** source: 16803888-Fig-2b
  *** xBraf[tAb] copptby[WB] Raf1[Ab] is decreased itpo xRheb
    *** cells: HEK293 in BMLS
    *** source: 16803888-Fig-2d
  *** xBraf[tAb] copptby[WB] xAkt1[GST] is detectable
    *** cells: HEK293<xBraf> in BMLS
    *** source: 10869359-Fig-2a
  *** xBraf[tAb] copptby[WB] xMek1[tAb] is detectable
    *** cells: HELA<xBraf><xMek1> in BMS
    *** inhibited by: xMek1(M308A/I310A) [substitution]
    *** source: 19541618-Fig-S1b
  *** xBraf[tAb] copptby[WB] xMek1[tAb] is detectable
    *** cells: HELA<xBraf><xMek1> in BMS
    *** unaffected by: xBraf(C696Y) [substitution]
    *** source: 19541618-Fig-S1b
  *** xBraf[tAb] copptby[WB] xMek2[tAb] is detectable
    *** cells: HELA<xBraf><xMek1> in BMS
    *** inhibited by: xMek2(M316A/I318A) [substitution]
    *** source: 19541618-Fig-S1b
  *** xBraf[tAb] copptby[WB] xMek2[tAb] is detectable
    *** cells: HELA<xBraf><xMek2> in BMS
    *** unaffected by: xBraf(C696Y) [substitution]
    *** source: 19541618-Fig-S1b
  *** xBraf[tAb] copptby[WB] xMlk3[tAb] is decreased itpo xMerlin
    *** cells: HEK293 in BMS
    *** source: 16537381-Fig-4c
  *** xBraf[tAb] copptby[WB] xMras(Q81L)"CA"[tAb] is unchanged itpo xShoc2
    *** cells: HEK293T in BMS
    *** source: 16630891-Fig-3a,4b
  *** xBraf[tAb] copptby[WB] xRaf1(mnr)"BXB"[tAb] is decreased itpo xBrap
    *** cells: HEK293<xRaf1><xBraf> in BMS
    *** source: 18332145-Fig-3c
  *** xBraf[tAb] copptby[WB] xRaf1(mnr)"BXB"[tAb] is detectable
    *** cells: HEK293<xRaf1><xBraf> in BMS
    *** unaffected by: xBraf(mnr)"KD" [substitution]
    *** source: 18332145-Fig-3a
  *** Braf[tAb] copptby[WB] xRaf1[tAb] is decreased itpo xBrap
    *** cells: HEK293<xRaf1> in BMS
    *** unaffected by: xRaf1(1-330)"Nterm" [substitution]
    *** source: 18332145-Fig-4b
  *** xBraf[tAb] copptby[WB] xRaf1[tAb] is detectable
    *** cells: HEK293<xBraf><xRaf1> in BMS
    *** reqs: Mlk3 [RNAi]
    *** source: 16537381-Fig-2b
  *** xBraf[tAb] copptby[WB] xRaf1[tAb] is increased itpo xHras(G12V)"CA"
    *** cells: COS7 in BMS
    *** source: 16364920-Fig-3f
  *** xBraf[tAb] copptby[WB] xRaf1[tAb] is increased itpo xYwhaz
    *** cells: COS1 in BMLS
    *** source: 16508002-Fig-4a
  *** xBraf[tAb] copptby[WB] xRap1a(G12V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1e
  *** xBraf[tAb] copptby[WB] xRap1a[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1e
  *** xBraf[tAb] copptby[WB] xRap2a(G12V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1e
  *** xBraf[tAb] copptby[WB] xRit1(Q79L)"CA"[tAb] is detectable
    *** cells: COS in BMS
    *** source: 15632082-Fig-3a
  *** xBraf[tAb] copptby[WB] xRit1(Q79L)"CA"[tAb] is detectable
    *** cells: COS in BMS
    *** unaffected by: xRit1(WT) [substitution]
    *** source: 15632082-Fig-3b
  *** xBraf[tAb] copptby[WB] xRras(G38V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1e
  *** xBraf[tAb] copptby[WB] xRras(G38V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186(D)
  *** xBraf[tAb] snaggedby[WB] rYwhab[GST] is detectable
    *** cells: HEK293<xBraf> in BMS
    *** unaffected by: xBraf(V600E) [substitution]
    *** unaffected by: xBraf(S365A) [substitution]
    *** unaffected by: xBraf(S729A) [substitution]
    *** inhibited by: xBraf(S365A/S729A) [substitution]
    *** source: 16702958-Fig-3a
  *** xBraf[tAb]IP IVKA(Erk?)[32P-ATP] is increased itpo xPlce1
    *** cells: COS7 in BMLS
    *** source: 11395506-Fig-5a
  *** xBraf[tAb]IP IVKA(Erk?)[32P-ATP] is increased itpo xRapGef2
    *** cells: COS7 in BMLS
    *** source: 11395506-Fig-5a
  *** xBraf[tAb]IP IVKA(Erk1,Elk1)[32P-ATP] is decreased itpo xAkt1(myr)"CA"
    *** cells: HEK293<xBraf> in BMLS
    *** source: 10869359-Fig-1a
  *** xBraf[tAb]IP IVKA(Erk1,Elk1)[32P-ATP] is decreased itpo xAkt1(myr)"CA"
    *** cells: HEK293<xBraf> in BMLS
    *** source: 10869359-Fig-1b
  *** xBraf[tAb]IP IVKA(Erk1,Elk1)[32P-ATP] is detectable
    *** cells: HEK293<xBraf> in BMLS
    *** enhanced by: xBraf(S364A) [substitution]
    *** enhanced by: xBraf(S428A/T439A) [substitution]
    *** enhanced by: xBraf(S364A/S428A/T439A) [substitution]
    *** source: 10869359-Fig-3
  *** xBraf[tAb]IP IVKA(Mek?,Erk?,Elk1)[32P-ATP] is decreased itpo xSgk1(S422D)"CA"
    *** cells: HEK293 in BMLS
    *** source: 11410590-Fig-1,2a
  *** xBraf[tAb]IP IVKA(Mek?)[32P-ATP] is detectable
    *** cells: NIH3T3<xBraf> in BMS
    *** enhanced by: xBraf(V600E) [substitution]
    *** enhanced by: xBraf(V600E/S151A/S401A/S750A/T753A) [substitution]
    *** enhanced by: xBraf(V600E/S729A) [substitution]
    *** enhanced by: xBraf(G469A) [substitution]
    *** enhanced by: xBraf(G469A/S151A/S401A/S750A/T753A) [substitution]
    *** enhanced by: xBraf(G469A/S729A) [substitution]
    *** enhanced by: xBraf(G464V) [substitution]
    *** enhanced by: xBraf(G464V/S151A/S401A/S750A/T753A) [substitution]
    *** enhanced by: xBraf(G464V/S729A) [substitution]
    *** enhanced by: xBraf(L597V) [substitution]
    *** enhanced by: xBraf(L597V/S151A/S401A/S750A/T753A) [substitution]
    *** enhanced by: xBraf(L597V/S729A) [substitution]
    *** enhanced by: xBraf(G466A) [substitution]
    *** enhanced by: xBraf(G466A/S151A/S401A/S750A/T753A) [substitution]
    *** enhanced by: xBraf(G466A/S729A) [substitution]
    *** inhibited by: xBraf(G466V) [substitution]
    *** inhibited by: xBraf(G466V/S151A/S401A/S750A/T753A) [substitution]
    *** inhibited by: xBraf(G466V/S729A) [substitution]
    *** inhibited by: xBraf(D594G) [substitution]
    *** inhibited by: xBraf(D594G/S151A/S401A/S750A/T753A) [substitution]
    *** inhibited by: xBraf(D594G/S729A) [substitution]
    *** source: 19933846-Fig-5a
  *** xBraf[tAb]IP IVKA(Mek1,Erk2,MBP)[32P-ATP] is unchanged itpo xSrc(Y527F)"CA"
    *** cells: COS7 in BMS
    *** source: 9020159-Fig-2b
  *** xBraf[tAb]IP IVKA(Mek1,Erk2)[32P-ATP] is unchanged itpo xRaf1
    *** cells: COS7 in BMS
    *** source: 16364920-Fig-4d
  *** xBraf[tAb]IP IVKA(Mek1,Erk2)[32P-ATP] is unchanged itpo xRap1a(G12V)"CA"
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1a
  *** xBraf[tAb]IP IVKA(Mek1,Erk2)[32P-ATP] is unchanged itpo xRap2a(G12V)"CA"
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1a
  *** xBraf[tAb]IP IVKA(Mek1,Erk2)[32P-ATP] is unchanged itpo xRheb(Q64L)"CA"
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1a
  *** xBraf[tAb]IP IVKA(Mek1,Erk2)[32P-ATP] is unchanged itpo xRin1(A78L)"CA"
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1a
  *** xBraf[tAb]IP IVKA(Mek1,Erk2)[32P-ATP] is unchanged itpo xRit1(Q79L)"CA"
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1a
  *** xBraf[tAb]IP IVKA(Mek1,Erk2)[32P-ATP] is unchanged itpo xRras(G12V)"CA"
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1a
  *** xBraf[tAb]IP IVKA(Mek1)[32P-ATP] is decreased itpo xRheb
    *** cells: HEK293 in BMLS
    *** source: 16803888-Fig-3d,3e
  *** xBraf[tAb]IP IVKA(Mek1)[32P-ATP] is increased itpo xPkac?
    *** cells: COS7 in BMLS
    *** enhanced by: xRap1a [addition]
    *** source: 9094716-Fig-5a
  *** xBraf[tAb]IP IVKA(Mek1)[32P-ATP] is increased itpo xPkac?
    *** cells: COS7 in BMLS
    *** inhibited by: xRap1a(T17N)"DN" [addition]
    *** source: 9094716-Fig-5b
  *** xBraf[tAb]IP IVKA(Mek1)[32P-ATP] is increased itpo xRap1a(G12V)"CA"
    *** cells: COS7 in BMLS
    *** source: 9094716-Fig-5
  *** xBraf[tAb]IP IVKA(Mek1)[32P-ATP] is increased itpo xRap1a(G12V)"CA"
    *** cells: PC12 in BMLS
    *** source: 9094716-Fig-6d
  *** xBraf[tAb]IP IVKA(Mek2,Erk2,MBP)[32P-ATP] is unchanged itpo xSrc(Y527F)"CA"
    *** cells: COS7 in BMS
    *** source: 9020159-Fig-2b
  *** xBraf[tAb]IP phos(S364)[phosAb] is increased itpo xSgk1(S422D)"CA"
    *** cells: HEK293 in BMS
    *** unaffected by: xSgk1(K127M)"KD" [addition]
    *** source: 11410590-Fig-2c
  *** xBraf[tAb]IP phos(S364)[phosAb] is unchanged itpo xAkt1(myr)"CA"
    *** cells: HEK293 in BMS
    *** source: 11410590-Fig-2c
  *** xBraf[tAb]IP phos(S364)[phosAb] is unchanged itpo xSgk1(K127M)"KD"
    *** cells: HEK293 in BMS
    *** source: 11410590-Fig-2c
  *** xBraf[tAb]IP phos(S446)[phosAb] is decreased itpo xRheb
    *** cells: HEK293 in BMLS
    *** source: 16803888-Fig-3c
  *** xBraf[tAb]IP phos(S446)[phosAb] is detectable-but unchanged itpo xHras(G12V)"CA"
    *** cells: HEK293<xBraf> in BMLS
    *** source: 15710605-Fig-1c
  *** xBraf[tAb]IP phos(S446)[phosAb] is increased itpo xPak1(L107F)"CA"
    *** cells: HEK293<xBraf> in BMLS
    *** source: 15710605-Fig-1d
  *** xBraf[tAb]IP phos(S446)[phosAb] is increased itpo xRit1(Q79L)"CA"
    *** cells: COS in BMS
    *** source: 15632082-Fig-4a
*** Brap--
  *** xBrap[tAb] copptby[WB] xHras(G12V)"CA"[tAb] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 14724641-Fig-1c
  *** xBrap[tAb] copptby[WB] xKsr1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 14724641-Fig-S3a
  *** xBrap[tAb]IP ubiq[UbAb] is detectable
    *** cells: NotReported in BMS
    *** inhibited by: xBrap(C264A)"E3-mut" [substitution]
    *** source: 14724641-Fig-3a
  *** xBrap[tAb]IP ubiq[UbAb] is increased itpo xHras(G12V)"CA"
    *** cells: NotReported in BMS
    *** inhibited by: xBrap(C264A)"E3-mut" [substitution]
    *** source: 14724641-Fig-3b
*** Brca1--
  *** Brca1[Ab] prot-exp[WB] is detectable
    *** cells: HELA in BMS
    *** does not req: Rnf8 [RNAi]
    *** source: 18001825-Fig-S4b
  *** Brca1[Ab] snaggedby[WB] sH2ax(123-143){phos(S140)}[GST] is undetectable
    *** cells: HELA in BMS "nuclear-extracts"
    *** unaffected by: sH2ax(123-143) [substitution]
    *** source: 16377563-Fig-1b
  *** xBtc[AP] secretion[AP] is detectable
    *** cells: mEFs<xProBtc> in BMS
    *** does not req: Adam17 [KO]
    *** source: 19158376-Fig-2
  *** xBtc[AP] secretion[AP] is unchanged itpo xAdam17
    *** cells: mEFs<Adam17~null><Adam10~null><xProBtc> in BMS
    *** source: 19158376-Fig-3a
  *** xBtc[AP] secretion[AP] is unchanged itpo xAdam17
    *** cells: mEFs<Adam17~null><xProBtc> in BMS
    *** source: 19158376-Fig-2i
  *** rBtk IVKA(peptide)[32P-ATP] is unchanged by rGnas{GTPgS}
    *** cells: none
    *** source: 9796816-Fig-1
*** Btk--
  *** xBtk[Ab] copptby[WB] xMyd88[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12724322(D)
  *** xBtk[Ab] copptby[WB] xTirap[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12724322(D)
*** Btrc--
  *** rBtrc[Ab] boundby[WB] rCtnnb1[tAb] is detectable
    *** cells: none
    *** comment: reaction contains rGsk3b
    *** comment: enhanced by addition of ATP to reaction mix
    *** comment: inhibited by addition of LambdaPPase
    *** source: 10074433-Fig-3b
  *** rBtrc[tAb] boundby[WB] rCtnnb1[Ab] is detectable
    *** cells: none
    *** comment: reqs rAxin1 in reaction mix
    *** source: 10228155-Fig-1c
  *** xBtrc[tAb] copptby[WB] Ctnnb1[Ab] is detectable
    *** cells: HEK293T<xBtrc><xAxin1> in BMS
    *** source: 10228155-Fig-1b
  *** xBtrc[tAb] copptby[WB] xMyc[tAb] is undetectable
    *** cells: HEK293T in BMS "treated with MG132 for 6 hr"
    *** source: 15103331-Fig-1b
  *** xBtrc[tAb] copptby[WB] xNfkb2[Ab] is increased itpo xNik
    *** cells: HEK293 in BMS
    *** inhibited by: xNfkb2(S866A/S870A) [substitution]
    *** inhibited by: xNfkb2(S99A/S108A/S115A/S123A/S872A) [substitution]
    *** source: 15140882-Fig-6a
  *** xBtrc[tAb] copptby[WB] xRbx1[tAb] is increased itpo xCul1
    *** cells: COS7 in BMS
    *** source: 11359933-Fig-2f
  *** xBtrc[tAb] snaggedby[WB] rMyc(51-66)[agarose] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15103331-Fig-3a
*** C4bpa--
  *** pC4bpa[Ab] boundby[WB] rCd40[agarose] is detectable
    *** cells: none
    *** source: 12818164-Fig-1d
  *** pC4bpa[biotin] receptor-binding[FACS] is detectable
    *** cells: BJAB in BMS
    *** source: 12818164-Fig-2a
  *** pC4bpa[biotin] receptor-binding[FACS] is detectable
    *** cells: DAUDI in BMS
    *** source: 12818164-Fig-2a
  *** pC4bpa[biotin] receptor-binding[FACS] is detectable
    *** cells: hBCs in BMS "EBV transformed"
    *** source: 12818164-Fig-2c
  *** pC4bpa[biotin] receptor-binding[FACS] is detectable
    *** cells: RAJI in BMS
    *** source: 12818164-Fig-2a
  *** pC4bpa[biotin] receptor-binding[FACS] is detectable
    *** cells: RAMOS in BMS
    *** source: 12818164-Fig-2a
  *** pC4bpa[biotin] receptor-binding[FACS] is undetectable
    *** cells: hBCs<Cd40~null> in BMS "EBV transformed"
    *** source: 12818164-Fig-2c
  *** pC4bpa[biotin] receptor-binding[FACS] is undetectable
    *** cells: HUT78 in BMS
    *** source: 12818164-Fig-2a
  *** pC4bpa[biotin] receptor-binding[FACS] is undetectable
    *** cells: JURKAT-E6.1 in BMS
    *** source: 12818164-Fig-2a
*** Cab39--
  *** xCab39[tAb] copptby[WB] xCdc37[GST] is undetectable
    *** cells: HEK293 in BMS
    *** source: 14517248-Fig-4a
  *** xCab39[tAb] copptby[WB] xLkb1[tAb] is detectable
    *** cells: HEK293<xAmpka1><xStrada> in BMS
    *** unaffected by: xLkb1(S325A/S428A) [substitution]
    *** source: 19187764-Fig-5c
  *** xCab39L[tAb] copptby[WB] xLkb1[GST] is detectable
    *** cells: HEK293<xStrada> in BMS
    *** source: 14517248-Fig-4c
  *** xCab39L[tAb] copptby[WB] xLkb1[GST] is detectable
    *** cells: HEK293<xStradb> in BMS
    *** source: 14517248-Fig-4c
  *** CAGA-reporter[Luc] is increased itpo (xSmad4 + xSmad3(S422A/S423A/S425A))
    *** cells: MV1LU in BMS
    *** inhibited by: xJnk?(mnr)"DN" [addition]
    *** enhanced by: xJnk? [addition]
    *** source: 10601313-Fig-4d
  *** CAGA-reporter[Luc] is increased itpo (xSmad4 + xSmad3)
    *** cells: MV1LU in BMS
    *** inhibited by: xJnk?(mnr)"DN" [addition]
    *** enhanced by: xJnk? [addition]
    *** source: 10601313-Fig-4d
  *** Calm[Ab] copptby[WB] xEef2k[tAb] is detectable
    *** cells: KB<xEef2k> in BMLS "treated with Ins (30 min)"
    *** enhanced by: xEef2k(S78A) [substitution]
    *** source: 15024086-Fig-6d
  *** Calm[Ab] copptby[WB] xRasGrf2[tAb] is detectable
    *** cells: HEK293T in BMLS
    *** unaffected by: Ionomycin [addition]
    *** source: 9032266-Fig-5a
  *** Camk2a[Ab] copptby[WB] Nos3[Ab] is detectable
    *** cells: COS in BMS
    *** inhibited by: xNos3(T495A) [substitution]
    *** unaffected by: xNos3(T495D) [substitution]
    *** source: 11397791(D)
  *** Canx[Ab] infraction(nuclear)[WB] is detectable
    *** cells: HL60 in BMS
    *** source: 9346962-Fig-4
  *** Canx[Ab] infraction(P100)[WB] is detectable
    *** cells: HL60 in BMS
    *** source: 9346962-Fig-4
  *** Canx[Ab] infraction(S100)[WB] is undetectable
    *** cells: HL60 in BMS
    *** source: 9346962-Fig-4
  *** Cap[Ab] copptby[WB] Bcar1[Ab] is detectable
    *** cells: ECV304 in BMS
    *** source: 14657239-Fig-4a
  *** xCap[Ab] copptby[WB] Bcar1[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 14657239-Fig-4b
  *** xCap[tAb] copptby[WB] Bcar1[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 14657239-Fig-5c
  *** xCard8[tAb] copptby[WB] xIrak4[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 15030775(D)
  *** xCard8[tAb] copptby[WB] xNlrp2[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 15030775(D)
  *** xCard8[tAb] copptby[WB] xNlrp3[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 15030775(D)
  *** xCard8[tAb] oligomerization[2TagPpt] is detectable
    *** cells: HEK293 in BMS
    *** source: 15030775(D)
*** Casp1--
  *** Casp1-gene mRNA[RTPCR] is increased itpo xStat1
    *** cells: U3A<Stat1~null> in BMLS
    *** unaffected by: xStat1(L407A/L409A) [substitution]
    *** source: 11823427-Fig-5c
  *** xCasp1(C285A)[tAb] copptby[WB] xRipk2[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 11051551(D)
  *** xCasp1(C285A)[tAb] oligomerization[2TagPpt] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xRac1(T17N)"DN" [addition]
    *** enhanced by: xRac1(G12V)"CA" [addition]
    *** source: 15060067(D)
  *** xCasp1(C285A)[tAb] oligomerization[2TagPpt] is increased itpo xRipk2
    *** cells: HEK293 in BMS
    *** source: 11051551(D)
  *** xCasp1(C285A)[tAb] snaggedby[WB] rIceberg[GST] is detectable
    *** cells: HEK293 in BMS
    *** source: 11051551(D)
  *** xCasp1[Ab] cleavage[WB] is detectable
    *** cells: HEK293<xCasp1><xIL1b> in BMS
    *** comment: cleavage products are 10 and 20 kD
    *** inhibited by: xRac1(T17N)"DN" [addition]
    *** inhibited by: GGTI2147 [addition]
    *** inhibited by: ToxinB [addition]
    *** source: 15060067(D)
  *** xCasp1[Ab] cleavage[WB] is increased itpo xPycard
    *** cells: HEK293 in BMS
    *** comment: cleavage product is 35 kD
    *** source: 12191486(D)
  *** xCasp1[Ab] cleavage[WB] is increased itpo xPycard
    *** cells: HEK293 in BMS
    *** comment: cleavage products are 10 and 20 kD
    *** inhibited by: xRac1(T17N)"DN" [addition]
    *** inhibited by: xLimk1(mnr)"DN" [addition]
    *** source: 15060067(D)
  *** xCasp1[Ab] cleavage[WB] is increased itpo xRac1(G12V)"CA"
    *** cells: HEK293 in BMS
    *** comment: cleavage products are 10 and 20 kD
    *** inhibited by: xLimk1(mnr)"DN" [addition]
    *** enhanced by: xPycard [addition]
    *** source: 15060067(D)
  *** xCasp1[Ab] cleavage[WB] is increased itpo xRac1(G12V)"CA"
    *** cells: HEK293<xCasp1><xIL1b> in BMS
    *** comment: cleavage products are 10 and 20 kD
    *** inhibited by: xRac1(F37L) [substitution]
    *** unaffected by: xRac1(Y40H) [substitution]
    *** source: 15060067(D)
  *** Casp1[Ab] copptby[WB] Pyrin[Ab] is detectable
    *** cells: THP1 in BMS
    *** source: 16785446(D)
  *** rCasp1[tAb] cleavage[WB] is increased by rRipk2
    *** cells: none
    *** comment: cleavage products are 10 and 20 kD
    *** inhibited by: rIceberg [addition]
    *** source: 11051551(D)
  *** xCasp1[tAb] cleavage[WB] is increased itpo xNlrp3
    *** cells: HEK293T<xPycard> in BMS
    *** comment: cleavage product is 35 kD
    *** reqs: xPycard [omission]
    *** enhanced by: xNlrp3(D303N) [substitution]
    *** enhanced by: xNlrp3(R260W) [substitution]
    *** unaffected by: xPyrin [addition]
    *** source: 16037825(D)
  *** xCasp1[tAb] cleavage[WB] is increased itpo xPyrin
    *** cells: HEK293T<xPycard> in BMS
    *** comment: cleavage product is 35 kD
    *** unaffected by: xPyrin(V726A) [substitution]
    *** unaffected by: xPyrin(M694V) [substitution]
    *** inhibited by: xPyrin(L16P/F24S) [substitution]
    *** source: 16037825(D)
  *** xCasp1[tAb] cleavage[WB] is increased itpo xRipk2
    *** cells: HEK293 in BMS
    *** comment: cleavage products are 10 and 20 kD
    *** inhibited by: xIceberg [addition]
    *** source: 11051551(D)
  *** xCasp1[tAb] copptby[WB] xCasp14[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp1[tAb] copptby[WB] xCradd[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12191486(D)
  *** xCasp1[tAb] copptby[WB] xNalp1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 17349957(D)
  *** xCasp1[tAb] copptby[WB] xNod1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 10329646(D)
  *** xCasp1[tAb] copptby[WB] xPyrin[tAb] is detectable
    *** cells: HEK293T<xPycard><xCasp1> in BMS
    *** source: 16037825(D)
  *** xCasp1[tAb] copptby[WB] xPyrin[tAb] is detectable
    *** cells: PT67<Pycard~null> in BMS
    *** source: 16785446(D)
  *** xCasp1[tAb] snaggedby[WB] rNlrp3[GST] is detectable
    *** cells: HEK293T<xPycard><xCasp1> in BMS
    *** unaffected by: rNlrp3(D303N) [substitution]
    *** reqs: xPycard [omission]
    *** source: 16037825(D)
  *** xCasp1[tAb] snaggedby[WB] rPyrin[GST] is detectable
    *** cells: HEK293T<xPycard><xCasp1> in BMS
    *** source: 16037825(D)
  *** xCasp1[tAb] snaggedby[WB] rTirap[GST] is detectable
    *** cells: HEK293 in BMS
    *** source: 17360653(D)
*** Casp2--
  *** Casp2-gene mRNA[RTPCR] is increased itpo xStat1
    *** cells: U3A<Stat1~null> in BMLS
    *** unaffected by: xStat1(L407A/L409A) [substitution]
    *** source: 11823427-Fig-5c
  *** Casp2[Ab] copptby[WB] Pyrin[Ab] is undetectable
    *** cells: THP1 in BMS
    *** source: 16785446(D)
  *** xCasp2[tAb] copptby[WB] xCasp14[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp2[tAb] copptby[WB] xCradd[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12191486(D)
  *** xCasp2[tAb] copptby[WB] xNod1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 10329646(D)
*** Casp3--
  *** Casp3-gene mRNA[RTPCR] is detectable-but unchanged itpo xStat1
    *** cells: U3A<Stat1~null> in BMLS
    *** unaffected by: xStat1(L407A/L409A) [substitution]
    *** source: 11823427-Fig-5c
  *** Casp3[Ab] copptby[WB] Pyrin[Ab] is undetectable
    *** cells: THP1 in BMS
    *** source: 16785446(D)
  *** xCasp3[Ab]IP cleavage[WB] is increased itpo xBad
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp3[Ab]IP cleavage[WB] is increased itpo xBak1
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp3[Ab]IP cleavage[WB] is increased itpo xBax
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp3[Ab]IP cleavage[WB] is increased itpo xBik
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp3[Ab]IP cleavage[WB] is increased itpo xFasR
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp3[Ab]IP cleavage[WB] is increased itpo xHrk
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp3[Ab]IP cleavage[WB] is increased itpo xTnfR1
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp3[Ab]IP cleavage[WB] is increased itpo xTnfRsf25
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp3[Ab]IP cleavage[WB] is increased itpo xTrailR1
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp3[Ab]IP cleavage[WB] is increased itpo xTrailR2
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** Casp3[ClAb] cleavage(A175)[ClAb] is decreased itpo xTak1
    *** cells: mEFs<Tak1~null> in BMS "treated with Tnf for 6,12 hr"
    *** unaffected by: xTak1(K34R) [substitution]
    *** reversed by: xTak1(K209R) [substitution]
    *** source: 19843958-Fig-2i
  *** xCasp3[tAb] copptby[WB] xNod1[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 10329646(D)
*** Casp4--
  *** Casp4[Ab] copptby[WB] Pyrin[Ab] is undetectable
    *** cells: THP1 in BMS
    *** source: 16785446(D)
  *** xCasp4[tAb] copptby[WB] xCasp1[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 15107016(D)
  *** xCasp4[tAb] copptby[WB] xCasp14[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp4[tAb] copptby[WB] xCradd[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 12191486(D)
  *** xCasp4[tAb] copptby[WB] xIpaf[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 15107016(D)
  *** xCasp4[tAb] copptby[WB] xNod1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 10329646(D)
  *** Casp5[Ab] copptby[WB] Pyrin[Ab] is undetectable
    *** cells: THP1 in BMS
    *** source: 16785446(D)
  *** xCasp5[Ab] copptby[WB] xCasp1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12191486(D)
  *** xCasp5[Ab] copptby[WB] xRipk2[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12191486(D)
  *** xCasp5[tAb] copptby[WB] xCradd[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 12191486(D)
  *** Casp6[Ab] copptby[WB] Pyrin[Ab] is undetectable
    *** cells: THP1 in BMS
    *** source: 16785446(D)
  *** xCasp6[Ab]IP cleavage[WB] is increased itpo xBak1
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp6[Ab]IP cleavage[WB] is increased itpo xBax
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp6[Ab]IP cleavage[WB] is increased itpo xBik
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp6[Ab]IP cleavage[WB] is increased itpo xFasR
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp6[Ab]IP cleavage[WB] is increased itpo xTnfR1
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp6[Ab]IP cleavage[WB] is increased itpo xTnfRsf25
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp6[Ab]IP cleavage[WB] is increased itpo xTrailR1
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp6[Ab]IP cleavage[WB] is increased itpo xTrailR2
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp6[Ab]IP cleavage[WB] is unchanged itpo xBad
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp6[Ab]IP cleavage[WB] is unchanged itpo xHrk
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp6[tAb] copptby[WB] xNod1[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 10329646(D)
  *** xCasp7(C186A)[tAb] snaggedby[WB] rIceberg[GST] is undetectable
    *** cells: HEK293 in BMS
    *** source: 11051551(D)
  *** Casp7[Ab] cleavage[WB] is increased itao Cdkn1b [RNAi]
    *** cells: MCF7 in BMLS
    *** source: 17237771(D)
  *** Casp7[Ab] cleavage[WB] is increased itao Cdkn1b [RNAi]
    *** cells: MCF7 in BMS
    *** source: 17237771(D)
  *** Casp7[Ab] copptby[WB] Pyrin[Ab] is undetectable
    *** cells: THP1 in BMS
    *** source: 16785446(D)
  *** xCasp7[Ab]IP cleavage[WB] is increased itpo xBad
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp7[Ab]IP cleavage[WB] is increased itpo xBak1
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp7[Ab]IP cleavage[WB] is increased itpo xBax
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp7[Ab]IP cleavage[WB] is increased itpo xBik
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp7[Ab]IP cleavage[WB] is increased itpo xFasR
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp7[Ab]IP cleavage[WB] is increased itpo xHrk
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp7[Ab]IP cleavage[WB] is increased itpo xTnfR1
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp7[Ab]IP cleavage[WB] is increased itpo xTnfRsf25
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp7[Ab]IP cleavage[WB] is increased itpo xTrailR1
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp7[Ab]IP cleavage[WB] is increased itpo xTrailR2
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp7[tAb] copptby[WB] xNod1[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 10329646(D)
  *** Casp8[Ab] copptby[WB] Pyrin[Ab] is undetectable
    *** cells: THP1 in BMS
    *** source: 16785446(D)
  *** xCasp8[Ab] copptby[WB] xCasp10[tAb] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xFlip [addition]
    *** source: 12887920(D)
  *** xCasp8[tAb] cleavage[WB] is increased itpo xFadd
    *** cells: HEK293 in BMS
    *** source: 12191486(D)
  *** xCasp8[tAb] cleavage[WB] is unchanged itpo xNod1
    *** cells: HEK293 in BMS
    *** source: 10329646(D)
  *** xCasp8[tAb] copptby[WB] xNod1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 10329646(D)
  *** xCasp9(C287A)[tAb] snaggedby[WB] rIceberg[GST] is undetectable
    *** cells: HEK293 in BMS
    *** source: 11051551(D)
  *** Casp9[Ab] copptby[WB] Pyrin[Ab] is undetectable
    *** cells: THP1 in BMS
    *** source: 16785446(D)
  *** xCasp9[tAb] cleavage[WB] is increased itpo xNod1
    *** cells: HEK293 in BMS
    *** source: 10329646(D)
  *** xCasp9[tAb] copptby[WB] xCradd[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 12191486(D)
  *** xCasp9[tAb] copptby[WB] xNod1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 10329646(D)
  *** Casp10[Ab] copptby[WB] Pyrin[Ab] is undetectable
    *** cells: THP1 in BMS
    *** source: 16785446(D)
  *** xCasp14[Ab]IP cleavage[WB] is unchanged itpo xBad
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp14[Ab]IP cleavage[WB] is unchanged itpo xBak1
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp14[Ab]IP cleavage[WB] is unchanged itpo xBax
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp14[Ab]IP cleavage[WB] is unchanged itpo xBik
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp14[Ab]IP cleavage[WB] is unchanged itpo xFasR
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp14[Ab]IP cleavage[WB] is unchanged itpo xHrk
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp14[Ab]IP cleavage[WB] is unchanged itpo xTnfR1
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp14[Ab]IP cleavage[WB] is unchanged itpo xTnfRsf25
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp14[Ab]IP cleavage[WB] is unchanged itpo xTrailR1
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp14[Ab]IP cleavage[WB] is unchanged itpo xTrailR2
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
  *** xCasp14[tAb] copptby[WB] xCasp10[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 9792675(D)
*** Cav1--
  *** Cav1[Ab] colocwith[IHC] Eea1[Ab] is undetectable
    *** cells: MV1LU in BMS
    *** source: 12717440-Fig-1a
  *** Cav1[Ab] copptby[WB] Smad7[Ab] is detectable
    *** cells: HK2 in BMLS
    *** unaffected by: Tgfb1 (24 hr) [stim]
    *** unaffected by: anti-Cd44 (24 hr) [stim]
    *** unaffected by: PD98059 [addition]
    *** source: 15084590(D)
  *** Cav1[Ab] copptby[WB] TgfbR1[Ab] is detectable
    *** cells: HK2 in BMLS
    *** unaffected by: Tgfb1 (24 hr) [stim]
    *** unaffected by: anti-Cd44 (24 hr) [stim]
    *** unaffected by: PD98059 [addition]
    *** source: 15084590(D)
  *** Cav1[Ab] copptby[WB] TgfbR1[Ab] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 11102446(D)
  *** xCav1[Ab] copptby[WB] xTgfbR1(T204D)"CA"[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 11102446(D)
  *** xCav1[Ab] copptby[WB] xTgfbR1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xCav1(del(61-101))"scaffolding-region-mut" [substitution]
    *** comment: coppt is disrupted by addition of Cav1-61-101 or Cav1-82-101 peptides
    *** source: 11102446(D)
*** Cbl--
*** Cblb--
  *** Cblb[Ab] copptby[WB] Cin85[Ab] is detectable
    *** cells: A431 in BMLS
    *** source: 12177062(D)
  *** Cblb[Ab] copptby[WB] xRankR[tAb] is detectable
    *** cells: HEK293T<xRankR><xSrc> in BMS
    *** unaffected by: xRankR(Y345F) [substitution]
    *** unaffected by: xRankR(Y440F) [substitution]
    *** inhibited by: xRankR(Y468F) [substitution]
    *** source: 11406619-Fig-3c
  *** xCblb[tAb] copptby[WB] xArhGef7[tAb] is increased itpo xSrc(mnr)"vSrc"
    *** cells: NIH3T3 in BMLS
    *** comment: coppt is from mixed lysates (xCblb vs (xArhGef7 + xSrc(mnr)"vSrc"))
    *** source: 16892055-Fig-3e
  *** xCblb[tAb] copptby[WB] xArhGef7[tAb] is increased itpo xSrc(mnr)"vSrc"
    *** cells: NIH3T3 in BMLS
    *** inhibited by: xArhGef7(Y619F) [substitution]
    *** source: 16892055-Fig-3f
*** Cbp--
  *** Cbp[Ab] boundto(Cdkn1b-gene)[ChIP] is detectable
    *** cells: HELA in BMS
    *** does not req: Arrb1 [RNAi]
    *** unaffected by: xArrb1 [addition]
    *** unaffected by: xArrb1(Q394L) [addition]
    *** source: 16325578-Fig-4a
  *** Cbp[Ab] boundto(Cdkn1b-gene)[ChIP] is unchanged itpo xArrb1
    *** cells: mEFs<Arrb1~null><Arrb2~null> in BMS
    *** unaffected by: xArrb1(Q394L) [substitution]
    *** source: 16325578-Fig-3a
  *** Cbp[Ab] boundto(Fos-gene)[ChIP] is detectable
    *** cells: HELA in BMS
    *** does not req: Arrb1 [RNAi]
    *** unaffected by: xArrb1 [addition]
    *** unaffected by: xArrb1(Q394L) [addition]
    *** source: 16325578-Fig-4a
  *** Cbp[Ab] boundto(Fos-gene)[ChIP] is unchanged itpo xArrb1
    *** cells: mEFs<Arrb1~null><Arrb2~null> in BMS
    *** unaffected by: xArrb1(Q394L) [substitution]
    *** source: 16325578-Fig-3a
  *** Cbp[Ab] boundto(Jun-gene)[ChIP] is detectable
    *** cells: HELA in BMS
    *** does not req: Arrb1 [RNAi]
    *** unaffected by: xArrb1 [addition]
    *** unaffected by: xArrb1(Q394L) [addition]
    *** source: 16325578-Fig-4a
  *** Cbp[Ab] boundto(Jun-gene)[ChIP] is unchanged itpo xArrb1
    *** cells: mEFs<Arrb1~null><Arrb2~null> in BMS
    *** unaffected by: xArrb1(Q394L) [substitution]
    *** source: 16325578-Fig-3a
  *** Cbp[Ab] copptby[WB] Hipk2[Ab] is detectable
    *** cells: MCF7 in BMS
    *** source: 11740489-Fig-6a
  *** Cbp[Ab] copptby[WB] Hipk2[Ab] is detectable
    *** cells: U2OS in BMS
    *** source: 11740489-Fig-6a
  *** xCbp[Ab] copptby[WB] xRela[tAb] is increased itpo xPkaca
    *** cells: COS in BMS
    *** inhibited by: xRela(S276A) [substitution]
    *** source: 9660950-Fig-2c
  *** Cbp[Ab] copptby[WB] xTicam2[tAb] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xIrf3 [addition]
    *** source: 14517278-Fig-3b
  *** CcL2-gene mRNA[RTPCR] is detectable
    *** cells: mEFs in BMS
    *** bkg inhibited by: TrichostatinA [addition]
    *** source: 18443042-Fig-9a
  *** CcL2-gene mRNA[RTPCR] is detectable
    *** cells: mEFs in BMS
    *** reqs: Jun [KO]
    *** source: 18443042-Fig-9a
  *** CcL2-gene mRNA[RTPCR] is increased itao Traf2 [KO]
    *** cells: mEFs in BMS
    *** source: 18997792-Fig-S1d
  *** CcL2-gene mRNA[RTPCR] is increased itao Traf3 [KO]
    *** cells: mEFs in BMS
    *** source: 18997792-Fig-S1d
  *** CcL2-gene promo-reporter[Luc] is increased itpo (xJun + xAtf2)
    *** cells: HEK293T<xIL1R1> in BMS
    *** comment: xJun and xAtf2 were tethered and expressed with a single plasmid
    *** source: 18443042-Fig-6b
*** CcL2-gene--
  *** CcL2[Ab] secretion[ELISA] is increased irt Flagellin (24 hr)
    *** cells: CAOV3<TLR5~pos> in BMS
    *** source: 19184006-Fig-3a 
  *** CcL2[Ab] secretion[ELISA] is increased irt Flagellin (24 hr)
    *** cells: OVCAR3<TLR5~pos> in BMS
    *** source: 19184006-Fig-3a 
  *** CcL2[Ab] secretion[ELISA] is increased irt Flagellin (24 hr)
    *** cells: SKOV3<TLR5~pos> in BMS
    *** source: 19184006-Fig-3a 
  *** CcL2[Ab] secretion[ELISA] is unchanged irt Flagellin (24 hr)
    *** cells: ES2<TLR5~neg> in BMS
    *** source: 19184006-Fig-3a 
  *** CcL5-gene mRNA[MicroArray] is detectable
    *** cells: THP1 in BMS
    *** reqs: Ampka1 [RNAi]
    *** source: 22833096-Table-S1a
  *** CcL5-gene mRNA[RTPCR] is increased itao Traf2 [KO]
    *** cells: mEFs in BMS
    *** source: 18997792-Fig-S1d
  *** CcL5-gene mRNA[RTPCR] is increased itao Traf3 [KO]
    *** cells: mEFs in BMS
    *** source: 18997792-Fig-S1d
  *** CcL5-gene promo-reporter[Luc] is increased itpo xTraf3
    *** cells: 9HTEO in BMS
    *** inhibited by: xTraf3(mnr)"DN" [addition]
    *** source: 12122011-Fig-9
  *** CcL5-gene promo-reporter[Luc] is increased itpo xTraf3
    *** cells: 9HTEO in BMS
    *** source: 12122011-Fig-10
  *** CcL5[Ab] secretion[ELISA] is detectable
    *** cells: 9HTEO in BMS
    *** inhibited by: xIkk1(K44A)"DN" [addition]
    *** inhibited by: xIkk2(K44A)"DN" [addition]
    *** source: 12122011-Fig-5b
  *** CcL5[Ab] secretion[ELISA] is detectable
    *** cells: HT29<xCd40> in BMS
    *** unaffected by: xCd40(T254A) [substitution]
    *** inhibited by: xCd40(Q263A) [substitution]
    *** inhibited by: xCd40(1-201) [substitution]
    *** source: 12122011-Fig-8
  *** CcL11[Ab] secretion[ELISA] is detectable
    *** cells: mEFs in BMS "treated with IL4 + Tnf for 72 hr"
    *** inhibited by: Ifng [cotreatment]
    *** source: 14733929-Fig-3b
  *** CcL11[Ab] secretion[ELISA] is detectable
    *** cells: mEFs in BMS "treated with IL4 + Tnf for 72 hr"
    *** inhibited by: Ifng [cotreatment]
    *** source: 14733929-Fig-5b
  *** CcL11[Ab] secretion[ELISA] is detectable
    *** cells: mEFs<Socs1~null> in BMS "treated with IL4 + Tnf for 72 hr"
    *** unaffected by: Ifng [cotreatment]
    *** source: 14733929-Fig-5b
  *** CcL11[Ab] secretion[ELISA] is detectable
    *** cells: mEFs<Stat1~null> in BMS "treated with IL4 + Tnf for 72 hr"
    *** unaffected by: Ifng [cotreatment]
    *** source: 14733929-Fig-3b
  *** CcL20-gene mRNA[RTPCR] is increased itpo xRela
    *** cells: HEK293T in BMS
    *** inhibited by: xFoxp3 [addition]
    *** source: 15790681-Fig-2d
  *** CcR7-gene mRNA[RTPCR] is detectable
    *** cells: mSpBCs in BMS "treated with anti-Cd40 (24 hr)"
    *** unaffected by: kMekk1(1-1188)"del-kinase-domain" [addition]
    *** source: 17143273-Fig-6c
  *** xCd2ap[tAb] copptby[WB] xCbl[GST] is detectable
    *** cells: HEK293T in BMS
    *** source: 11067845-Fig-5a
  *** Cd3z[Ab] copptby[WB] xIL2Ra[Ab] is detectable
    *** cells: COS in BMS
    *** unaffected by: xFyn [addition]
    *** unaffected by: xPag1 [addition]
    *** source: 10790433-Fig-8a
  *** Cd14[Ab] colocwith[FRET] Golga2[Ctxb] is detectable
    *** cells: HEK293<xTLR2><xCd14> in BMS
    *** unaffected by: LTA-Sa (tnr) [stim]
    *** source: 15247273(D)
  *** Cd14[Ab] colocwith[FRET] Golga2[Ctxb] is detectable
    *** cells: hPBMCs in BMS
    *** unaffected by: LTA-Sa (10 min) [stim]
    *** unaffected by: Lps (10 min) [stim]
    *** unaffected by: Pam3Csk4 (10 min) [stim]
    *** unaffected by: FSL1 (10 min) [stim]
    *** source: 16880211(D)
  *** Cd36[Ab] colocwith[FRET] Golga2[Ctxb] is detectable
    *** cells: hPBMCs in BMS
    *** unaffected by: LTA-Sa (10 min) [stim]
    *** unaffected by: Lps (10 min) [stim]
    *** unaffected by: Pam3Csk4 (10 min) [stim]
    *** unaffected by: FSL1 (10 min) [stim]
    *** source: 16880211(D)
  *** Cd40[Ab] locatedin(cellmembrane)[IHC] is detectable
    *** cells: M1241 in BMS
    *** unaffected by: xTraf2 [addition]
    *** source: 10748139-Fig-1
  *** Cd44-gene mRNA[MicroArray] is detectable
    *** cells: THP1 in BMS
    *** reqs: Ampka1 [RNAi]
    *** source: 22833096-Table-S1a
  *** Cd44-gene mRNA[RTPCR] is detectable
    *** cells: THP1 in BMS
    *** reqs: Ampka1 [RNAi]
    *** source: 22833096-Fig-4c
  *** Cd44[Ab] prot-exp[WB] is decreased itao Tnik [RNAi]
    *** cells: SW480 in BMS
    *** source: 21710659-Fig-1a
  *** Cd74-gene mRNA[MicroArray] is detectable
    *** cells: THP1 in BMS
    *** reqs: Ampka1 [RNAi]
    *** source: 22833096-Table-S2a
  *** Cdc37[Ab] copptby[WB] Ikk1[Ab] is detectable
    *** cells: HELA in BMS
    *** unaffected by: Tnf (tnr) [stim]
    *** source: 11864612-Fig-3a,4a
  *** Cdc37[Ab] copptby[WB] Ksr1[Ab] is detectable
    *** cells: PC12 in BMS "differentiated with Ngf for 5 days"
    *** source: 10409742-Fig-2g
  *** Cdc37[Ab] copptby[WB] Mlk3[Ab] is detectable
    *** cells: MCF7 in BMS
    *** source: 15001580(D)
  *** Cdc37[Ab] copptby[WB] Nemo[Ab] is detectable
    *** cells: HELA in BMS
    *** inhibited by: Geldanamycin [addition]
    *** source: 11864612-Fig-5a
  *** Cdc37[Ab] copptby[WB] Nemo[Ab] is detectable
    *** cells: HELA in BMS
    *** unaffected by: Tnf (tnr) [stim]
    *** source: 11864612-Fig-4a
  *** Cdc37[Ab] copptby[WB] xKsr1[Ab] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: Geldanamycin [addition]
    *** source: 10409742-Fig-1f
  *** Cdc37[Ab] copptby[WB] xMlk3[Ab] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: xCdc42(G12V)"CA" [addition]
    *** unaffected by: xMlk3(K144A)"KD" [substitution]
    *** source: 15001580(D)
  *** Cdc37[Ab] copptby[WB] xMlk3[tAb] is detectable
    *** cells: MCF7 in BMS "containing AP21967 to induce xMlk3"
    *** source: 15001580(D)
  *** Cdc37[MS] copptby[WB] xMlk3[tAb] is detectable
    *** cells: MCF7 in BMS "containing AP21967 to induce xMlk3"
    *** source: 15001580(D)
  *** rCdc42 GDP-dissociation[3H-GDP] is unchanged by rRalGds
    *** cells: none
    *** source: 8094051-Fig-5
  *** rCdc42 GDP-dissociation[3H-GDP] is unchanged by rSos1(601-1019)
    *** cells: none
    *** source: 8493579-Fig-1d
  *** rCdc42 GDP-dissociation[3H-GDP] is unchanged by xArhGef6[tAb]IP
    *** cells: none
    *** IPfrom: COS7<xArhGef6> in BMS
    *** source: 15306850-Fig-2a 
  *** rCdc42 GDP-dissociation[3H-GDP] is unchanged by xRapGef1[tAb]IP
    *** cells: none
    *** source: 11309621-Fig-4a
  *** rCdc42 GDP-dissociation[3H-GDP] is unchanged by xVav3(144-847)[His]IP
    *** cells: none
    *** IPfrom: SF9 in BMS
    *** source: 10523675-Fig-3d
  *** rCdc42 GDP-dissociation[Mant-GDP] is unchanged by rArhGef2(226-643)
    *** cells: none
    *** source: 11595749-Fig-1b
  *** rCdc42 GDP-dissociation[Mant-GDP] is unchanged by rArhGef2(226-643)
    *** cells: none
    *** source: 11595749-Fig-2b
  *** rCdc42 GDP-dissociation[Mant-GDP] is unchanged by rArhGef2(226-643)
    *** cells: none
    *** source: 11595749-Fig-2d
  *** rCdc42 GDP-dissociation[Mant-GDP] is unchanged by rTiam1(1033-1606)
    *** cells: none
    *** source: 11595749-Fig-1c
  *** rCdc42 GDP-dissociation[Mant-GDP] is unchanged by rTrio(1225-1537)
    *** cells: none
    *** source: 11595749-Fig-1a
  *** rCdc42 GDP-dissociation[Mant-GDP] is unchanged by rTrio(1225-1537)
    *** cells: none
    *** source: 11595749-Fig-2b
  *** rCdc42 GDP-dissociation[Mant-GDP] is unchanged by rTrio(1225-1537)
    *** cells: none
    *** source: 11595749-Fig-2d
  *** rCdc42 GTP-association[32P-GTP] is unchanged by rSos1(601-1019)
    *** cells: none
    *** source: 8493579-Fig-1e
  *** rCdc42 GTP-association[35S-GTPgS] is increased by rAbr(104-383)
    *** cells: none
    *** source: 9659915-Fig-6a
  *** rCdc42 GTP-association[35S-GTPgS] is increased by rArhGef6(155-545)
    *** cells: none
    *** source: 9659915-Fig-6a
  *** rCdc42 GTP-association[35S-GTPgS] is unchanged by xVav3(144-847)[His]IP
    *** cells: none
    *** IPfrom: SF9 in BMS
    *** source: 10523675-Fig-3e
  *** rCdc42 GTP-association[Mant-GTP] is increased by rSpata13(92-652/W156A)
    *** cells: none
    *** inhibited by: rSpata13(WT) [substitution]
    *** source: 17704816-Fig-7b
  *** rCdc42 GTP-hydrolysis[32P-GTP] is unchanged by rSipa1
    *** cells: none
    *** source: 9346962-Fig-3b
  *** rCdc42 GTP-hydrolysis[Pi-release] is increased by rArhGap1
    *** cells: none
    *** source: 10843989-Fig-9c
*** Cdc42--
  *** xCdc42(G12V)[tAb] snaggedby[WB] rElmo2(1-362)[GST] is undetectable
    *** cells: HEK293T<xCdc42(G12V)> in BMS
    *** source: 12879077-Fig-1b
  *** xCdc42(G12V)[tAb] snaggedby[WB] rRtkn(mnr)"RBD"[GST] is undetectable
    *** cells: HEK293T<xCdc42(G12V)> in BMS
    *** source: 12879077-Fig-1b
  *** rCdc42(Q61L)[32P] phos[32P-ATP] is increased by rSrc(Y530F)"CA"
    *** cells: none
    *** inhibited by: rCdc42(Y64F) [substitution]
    *** source: 14506284-Fig-2b
  *** xCdc42(Q61L)[tAb]IP Yphos[pYAb] is increased itpo xSrc(Y530F)"CA"
    *** cells: COS7 in BMLS
    *** inhibited by: xCdc42(Q61L/Y64F)"CA" [substitution]
    *** inhibited by: xCdc42(Q61L/Y64E)"CA" [substitution]
    *** source: 14506284-Fig-2c
  *** xCdc42(Q61L)[tAb]IP Yphos[pYAb] is increased itpo xSrc(Y530F)"CA"
    *** cells: COS7<xSrc> in BMS
    *** inhibited by: xCdc42(Q61L/Y64F) [substitution]
    *** inhibited by: xCdc42(Q61L/Y64E) [substitution]
    *** source: 14506284-Fig-4
  *** xCdc42(Q61L)[tAb]IP Yphos[pYAb] is increased itpo xSrc(Y530F)"CA"
    *** cells: COS7<xSrc> in BMS
    *** unaffected by: xAck2 [addition]
    *** unaffected by: xWasp [addition]
    *** unaffected by: xPak1 [addition]
    *** source: 14506284-Fig-3r
  *** rCdc42[Ab] boundby[WB] rArhGef4(mnr)"APC-binding-mutant"[Resin] is undetectable
    *** cells: none
    *** source: 10947987-Fig-3a
  *** Cdc42[Ab] colocwith[IHC] Stau1[Ab] is detectable
    *** cells: SHSY5Y in BMS "differentiated with retinoic acid for 7 days"
    *** source: 15121898(D)
  *** Cdc42[Ab] copptby[WB] Pak2[Ab] is decreased itpo xErbin
    *** cells: AKR2B in BMLS "treated with Tgfb1 for 45 min"
    *** reqs: Merlin [RNAi]
    *** source: 19289088-Fig-5d
  *** Cdc42[Ab] copptby[WB] xStau1[tAb] is detectable
    *** cells: HEK293T in BMS "infected with vaccinia vTf7-3 virus"
    *** source: 15121898(D)
  *** Cdc42[Ab] GTP-association[BDPD] is decreased itpo xCdGap
    *** cells: COS1 in BMLS
    *** source: 14699061-Fig-7d
  *** Cdc42[Ab] GTP-association[BDPD] is increased itpo xRac1(Q61L)"CA"
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-4
  *** Cdc42[Ab] GTP-association[BDPD] is increased itpo xRhog(Q61L)"CA"
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-4
  *** xCdc42[tAb] GTP-association[BDPD] is detectable
    *** cells: HEK293<xCdc42> in BMS
    *** unaffected by: xCdc42(G12V) [substitution]
    *** inhibited by: xCdc42(T17N) [substitution]
    *** source: 20890305-Fig-4b
  *** xCdc42[tAb] GTP-association[BDPD] is detectable-but unchanged itpo xMerlin
    *** cells: HEK293<xCdc42> in BMS
    *** source: 20890305-Fig-4b
  *** xCdc42[tAb] GTP-association[BDPD] is increased itao Merlin [RNAi]
    *** cells: HEK293<xCdc42> in BMS
    *** source: 20890305-Fig-4a
  *** xCdc42[tAb] GTP-association[BDPD] is increased itpo (xGnb1 + xGng2 + xArhGef6)
    *** cells: COS7 in BMS
    *** enhanced by: xPak1 [addition]
    *** source: 12887923-Fig-3a
  *** xCdc42[tAb] GTP-association[BDPD] is increased itpo (xGnb1 + xGng2 + xPak1)
    *** cells: COS7 in BMS
    *** enhanced by: xArhGef6 [addition]
    *** source: 12887923-Fig-3a
  *** xCdc42[tAb] GTP-association[BDPD] is increased itpo xDock4(P1718L)
    *** cells: HEK293T in BMS
    *** inhibited by: xDock4(WT) [substitution]
    *** source: 12628187-Fig-4c
  *** xCdc42[tAb] GTP-association[BDPD] is increased itpo xSrc(Y530F)"CA"
    *** cells: COS7 in BMLS
    *** source: 14506284-Fig-6
  *** xCdc42[tAb] GTP-association[BDPD] is increased itpo xSrc(Y530F)"CA"
    *** cells: COS7 in BMLS
    *** source: 14506284-Fig-9
  *** xCdc42[tAb] GTP-association[BDPD] is increased itpo xSrc(Y530F)"CA"
    *** cells: COS7 in BMLS
    *** unaffected by: xCdc42(Y64F) [substitution]
    *** comment: GTP bound xCdc42 is Yphosed
    *** source: 14506284-Fig-7
  *** xCdc42[tAb] GTP-association[BDPD] is unchanged itpo (xArhGef6 + xPak1)
    *** cells: COS7 in BMS
    *** source: 12887923-Fig-3a
  *** xCdc42[tAb]IP GTP-association[35S-GTPgS] is unchanged by rRgl1
    *** cells: none
    *** IPfrom: SF9 in BMS "cytosolic-fraction"
    *** source: 9099691-Fig-5
  *** xCdc42[tAb]IP GTP-association[35S-GTPgS] is unchanged by rRgl1
    *** cells: none
    *** IPfrom: SF9 in BMS "membrane-fraction"
    *** source: 9099691-Fig-5
  *** xCdc42[tAb]IP GTP-association[TLC] is increased itpo xVav1(67-845)
    *** cells: COS7 in BMS
    *** comment: results are reported as bound labelled GDP
    *** source: 8990121-Fig-3a
  *** xCdc42[tAb]IP Yphos[pYAb] is increased itpo xSrc(Y530F)"CA"
    *** cells: COS7 in BMLS
    *** inhibited by: xSrc(WT) [substitution]
    *** source: 14506284-Fig-2a
  *** xCdc42[tAb]IP Yphos[pYAb] is increased itpo xSrc(Y530F)"CA"
    *** cells: COS7 in BMLS
    *** unaffected by: xCdc42(Q61L)"CA" [substitution]
    *** source: 14506284-Fig-2a
  *** xCdc42[tAb]IP Yphos[pYAb] is increased itpo xSrc(Y530F)"CA"
    *** cells: COS7<xSrc> in BMS
    *** unaffected by: xCdc42(Q61L)"CA" [substitution]
    *** source: 14506284-Fig-4
  *** rCdc42{GDP} GTP-association[35S-GTPgS] is unchanged by rLck
    *** cells: none
    *** source: 8990121-Fig-1a
  *** rCdc42{GDP} GTP-association[35S-GTPgS] is unchanged by rVav1{Yphos}
    *** cells: none
    *** comment: rVav1 was phosphorylated by rLck
    *** unaffected by: rVav1 [substitution]
    *** source: 8990121-Fig-2a
  *** rCdc42{GDP} GTP-association[35S-GTPgS] is unchanged by xVav1{phos}[His]IP
    *** cells: none
    *** IPfrom: SF9 in BMS
    *** comment: Vav1-IP was phosphorylated by rLck
    *** inhibited by: xVav1[His]IP [substitution]
    *** source: 9822605-Fig-4a
  *** rCdc42{GDP} GTP-association[35S-GTPgS] is unchanged by xVav2(mnr)"oncoprotein"{phos}[His]IP
    *** cells: none
    *** IPfrom: SF9 in BMS
    *** comment: Vav2-IP was phosphorylated by rLck
    *** unaffected by: xVav2(mnr)"oncoprotein"[His]IP [substitution]
    *** source: 9822605-Fig-5b
  *** rCdc42{GDP} GTP-association[35S-GTPgS] is unchanged by xVav2{phos}[His]IP
    *** cells: none
    *** IPfrom: SF9 in BMS
    *** comment: Vav2-IP was phosphorylated by rLck
    *** inhibited by: xVav2[His]IP [substitution]
    *** source: 9822605-Fig-4a
  *** rCdc42{GDP} GTP-association[35S-GTPgS] is unchanged by xVav3{phos}[His]IP
    *** cells: none
    *** IPfrom: SF9 in BMS
    *** comment: Vav1-IP was phosphorylated by rLck
    *** unaffected by: xVav3[His]IP [substitution]
    *** source: 10523675-Fig-4c
  *** rCdc42{GTPgS}[32P] boundby[WB] rMekk3[Resin] is detectable
    *** cells: none
    *** source: 9305638-Fig-7
  *** rCdc42{GTPgS}[32P] boundby[WB] rMekk4[Resin] is detectable
    *** cells: none
    *** source: 9305638-Fig-7
*** Cdc42bpa--
  *** Cdc42bpa[Ab] copptby[WB] xCdc42(Q61L)[tAb] is detectable
    *** cells: COS7<xSrc> in BMS
    *** unaffected by: xSrc(Y530F) [substitution]
    *** source: 14506284-Fig-3l
*** Cdh1--
  *** Cdh1[Ab] colocwith[IHC] Ptprf[Ab] is detectable
    *** cells: NBTII in BMS
    *** source: 10187801-Fig-4
  *** Cdh1[Ab] copptby[WB] Ctnnb1[Ab] is decreased itpo xKras(G12V)"CA"
    *** cells: IEC18 in BMS
    *** source: 12640114-Fig-3c
  *** Cdh1[Ab] copptby[WB] Ctnnb1[Ab] is detectable
    *** cells: RWP1 in BMS
    *** unaffected by: xFer [addition]
    *** unaffected by: xFyn [addition]
    *** source: 12640114-Fig-2a
  *** Cdh1[Ab] copptby[WB] Ctnnd1[Ab] is increased itpo xKras(G12V)"CA"
    *** cells: IEC18 in BMS
    *** source: 12640114-Fig-6a
  *** Cdh1[Ab] copptby[WB] EgfR[Ab] is detectable
    *** cells: MDCK in BMS
    *** unaffected by: Egf (10 min) [stim]
    *** source: 11716761-Fig-2g
  *** Cdh1[Ab] copptby[WB] EgfR[Ab] is detectable
    *** cells: SCC12F in BMS "containing hydrocortisone"
    *** unaffected by: Egf (10 min) [stim]
    *** source: 11716761-Fig-2c
  *** Cdh1[Ab] copptby[WB] Fyn[Ab] is detectable
    *** cells: IEC18 in BMS
    *** enhanced by: xKras(G12V)"CA" [addition]
    *** source: 12640114-Fig-6b
  *** Cdh1[Ab] copptby[WB] Numb[Ab] is detectable
    *** cells: MDCK2 in BMS
    *** inhibited by: Src(mnr)"vSrc" [addition]
    *** partially inhibited by: Pervanadate [addition]
    *** enhanced by: PP2 [addition]
    *** source: 19609305-Fig-1a
  *** Cdh1[Ab] copptby[WB] Pik3rs[Ab] is detectable
    *** cells: MDCK in BMS
    *** unaffected by: Egf (10 min) [stim]
    *** source: 11716761-Fig-2e
  *** Cdh1[Ab] copptby[WB] Pik3rs[Ab] is detectable
    *** cells: SCC12F in BMS "containing hydrocortisone"
    *** unaffected by: Egf (10 min) [stim]
    *** source: 11716761-Fig-2a
  *** Cdh1[Ab] copptby[WB] Ptprf[Ab] is detectable
    *** cells: MCF7 in BMS
    *** unaffected by: Egf (30 min) [stim]
    *** source: 10187801-Fig-5a
  *** Cdh1[Ab] copptby[WB] xCtnnb1[tAb] is detectable
    *** cells: IEC18<xKras(G12V)"CA"> in BMS
    *** unaffected by: rCtnnb1(Y142F) [substitution]
    *** source: 12640114-Fig-4b
  *** Cdh1[Ab] prot-exp[WB] is detectable-but unchanged itpo xBraf
    *** cells: MCF10A in BMLS
    *** inhibited by: xBraf(V600E) [substitution]
    *** unaffected by: xBraf(R188L) [substitution]
    *** inhibited by: xBraf(V600E/R118L) [substitution]
    *** unaffected by: xBraf(S446A/S5447A) [substitution]
    *** inhibited by: xBraf(V600E/S446A/S5447A) [substitution]
    *** unaffected by: xBraf(S365A/S446A/S447A/D448A/D449A) [substitution]
    *** inhibited by: xBraf(V600E/S365A/S446A/S447A/D448A/D449A) [substitution]
    *** unaffected by: xBraf(S365A) [substitution]
    *** source: 16702958-Fig-8a
  *** Cdh1[Ab] prot-exp[WB] is detectable-but unchanged itpo xBraf
    *** cells: MCF10A in BMLS
    *** inhibited by: xBraf(V600E) [substitution]
    *** unaffected by: xBraf(S729A) [substitution]
    *** inhibited by: xBraf(V600E/S729A) [substitution]
    *** source: 16702958-Fig-8b
  *** Cdh1[Ab]IP Yphos[pYAb] is increased itpo xSrc(mnr)"vSrc"
    *** cells: MDCK2 in BMS
    *** source: 19609305-Fig-1a
*** Cdk2--
  *** rCdk2[32P] phos[32P-ATP] is increased by Cdk7[Ab]IP
    *** cells: none
    *** IPfrom: hFibros in BMS
    *** comment: inhibited by addition of rCdkn1a + rCyclinA? to kinase reaction
    *** comment: inhibited by addition of rCdkn1b + rCyclinA? to kinase reaction
    *** comment: unaffected by addition of rCdkn1c + rCyclinA? to kinase reaction
    *** source: 7629134-Fig-2
  *** rCdk2[32P] phos[32P-ATP] is increased by Cdk7[Ab]IP
    *** cells: none
    *** IPfrom: hFibros in BMS
    *** comment: unaffected by addition of rCdkn1a to kinase reaction
    *** comment: unaffected by addition of rCdkn1b to kinase reaction
    *** source: 7629134-Fig-1b
  *** Cdk2[Ab] prot-exp[WB] is detectable
    *** cells: HELA in BMS
    *** unaffected by: Fbxw7 [KO]
    *** source: 15103331-Fig-5a
  *** Cdk2[Ab] prot-exp[WB] is detectable
    *** cells: HELA in BMS
    *** unaffected by: Fbxw7 [RNAi]
    *** source: 15103331-Fig-4b
  *** Cdk2[Ab] prot-exp[WB] is detectable
    *** cells: HELA in BMS
    *** unaffected by: Skp2 [RNAi]
    *** source: 15103331-Fig-4b
  *** Cdk2[Ab] prot-exp[WB] is detectable
    *** cells: mSpCs in BMS
    *** repressed by: Stat5a and/or Stat5b [DKO]
    *** source: 10072077-Fig-6a
  *** xCdk2[Ab] snaggedby[WB] rCdkn1a[GST] is detectable
    *** cells: Ecoli<xCdk2> in BMS
    *** unaffected by: rCdkn1a(del(1-29)) [substitution]
    *** unaffected by: rCdkn1a(del(17-24)) [substitution]
    *** unaffected by: rCdkn1a(del(24-29)) [substitution]
    *** unaffected by: rCdkn1a(del(43-47)) [substitution]
    *** inhibited by: rCdkn1a(del(53-58)) [substitution]
    *** unaffected by: rCdkn1a(1-90) [substitution]
    *** unaffected by: rCdkn1a(1-90/del(17-24)) [substitution]
    *** source: 8756624-Fig-1d
  *** xCdk2[Ab] snaggedby[WB] rCyclinE?[GST] is detectable
    *** cells: Ecoli<xCdk2> in BMS
    *** inhibited by: rCyclinE?(1-127) [substitution]
    *** inhibited by: rCyclinE?(1-216) [substitution]
    *** inhibited by: rCyclinE?(1-326) [substitution]
    *** unaffected by: rCyclinE?(1-334) [substitution]
    *** source: 8756624-Fig-1d
  *** xCdk2[Ab] snaggedby[WB] xE2f1[GST] is detectable
    *** cells: SF9<xCyclinA1><xCdk2> in BMS
    *** reqs: xCyclinA1 [omission]
    *** source: 10022926-Fig-2b
  *** Cdk2[Ab]IP IVKA(HistH1)[32P-ATP] is decreased itpo xHras(S17N)
    *** cells: IEC18C41 in BMS
    *** source: 8798398-Fig-5a
  *** Cdk2[Ab]IP IVKA(HistH1)[32P-ATP] is detectable
    *** cells: hFibros in BMS
    *** comment: inhibited by addition of rCdkn1a to kinase reaction
    *** source: 7629134-Fig-1a
  *** Cdk2[Ab]IP IVKA(HistH1)[32P-ATP] is detectable
    *** cells: hFibros in BMS
    *** comment: inhibited by addition of rCdkn1b to kinase reaction
    *** source: 7629134-Fig-1a
  *** Cdk2[Ab]IP IVKA(Rb1)[32P-ATP] is increased itpo xCdkn2b
    *** cells: MV1LU in BMS
    *** source: 12150994-Fig-6f
  *** Cdk2[Ab]IP IVKA(Smad2)[32P-ATP] is detectable
    *** cells: MV1LU in BMS
    *** inhibited by: rCdk2(283-298) [addition]
    *** source: 15241418-Fig-1c
  *** Cdk2[Ab]IP IVKA(Smad3)[32P-ATP] is detectable
    *** cells: MV1LU in BMS
    *** inhibited by: rCdk2(283-298) [addition]
    *** source: 15241418-Fig-1c
  *** Cdk2[Ab]IP IVKA(Smad4)[32P-ATP] is undetectable
    *** cells: MV1LU in BMS
    *** source: 15241418-Fig-1c
  *** xCdk2[tAb]IP phos(T160)[phosAb] is detectable
    *** cells: HEK293T<xCdk2><xCyclinE?> in BMS
    *** unaffected by: xCdk2(T41A/Y15F) [substitution]
    *** inhibited by: xCdk2(T160A) [substitution]
    *** source: 10903150-Fig-5a
  *** Cdk4[Ab] prot-exp[WB] is detectable
    *** cells: HACAT in BMS "containing Tgfb1"
    *** reqs: Pdpk1 [RNAi]
    *** source: 17327236-Fig-7d
  *** Cdk4[Ab] prot-exp[WB] is detectable
    *** cells: HELA in BMS "containing Tgfb1"
    *** reqs: Pdpk1 [RNAi]
    *** source: 17327236-Fig-7d
  *** Cdk4[Ab] prot-exp[WB] is detectable
    *** cells: mSpCs in BMS
    *** does not req: Stat5a or Stat5b [DKO]
    *** source: 10072077-Fig-6a
  *** Cdk4[Ab]IP IVKA(Smad2)[32P-ATP] is detectable
    *** cells: MV1LU in BMS
    *** inhibited by: rCdk4(282-303) [addition]
    *** source: 15241418-Fig-1a
  *** Cdk4[Ab]IP IVKA(Smad3)[32P-ATP] is detectable
    *** cells: MV1LU in BMS
    *** inhibited by: rCdk4(282-303) [addition]
    *** source: 15241418-Fig-1a
  *** Cdk4[Ab]IP IVKA(Smad3)[32P-ATP] is detectable
    *** cells: MV1LU in BMS
    *** source: 15241418-Fig-S1a
  *** Cdk4[Ab]IP IVKA(Smad3)[32P-ATP] is undetectable
    *** cells: MV1LU in BMS
    *** source: 15241418-Fig-1a
  *** xCdk4[tAb] copptby[WB] Bad[Ab] is undetectable
    *** cells: HEK293<xCdk4><xBad> in BMS
    *** source: 9346240-Fig-5a
  *** rCdk6[32P] phos[32P-ATP] is increased by Cdk7[Ab]IP
    *** cells: none
    *** IPfrom: hFibros in BMS
    *** comment: enhanced by addition of rCyclinD1 to kinase reaction
    *** inhibited by: rCdk6(T177A) [substitution]
    *** source: 7629134-Fig-3
  *** rCdk6[32P] phos[32P-ATP] is increased by Cdk7[Ab]IP
    *** cells: none
    *** IPfrom: hFibros in BMS
    *** comment: inhibited by addition of rCdkn1c + rCyclinD1 to kinase reaction
    *** source: 7629134-Fig-4
  *** Cdk7[Ab] snaggedby[WB] rElk1(307-428){phos}[Gal4-DBD-G5TATA] is detectable
    *** cells: mESCs in BMS "nuclear extracts"
    *** inhibited by: rElk1(307-428) [substitution]
    *** source: 14506297-Fig-3
  *** Cdk7[Ab] snaggedby[WB] rElk1(307-428){phos}[Gal4-DBD-G5TATA] is detectable
    *** cells: mESCs in BMS "nuclear extracts"
    *** reqs: Med23 [KO]
    *** source: 14506297-Fig-3
  *** Cdk7[Ab]IP IVKA(Cdk2)[32P-ATP] is detectable
    *** cells: hFibros in BMS
    *** comment: inhibited by addition of rCdkn1a + rCyclinA? to kinase reaction
    *** comment: inhibited by addition of rCdkn1b + rCyclinA? to kinase reaction
    *** comment: unaffected by addition of rCdkn1c + rCyclinA? to kinase reaction
    *** source: 7629134-Fig-2
  *** Cdk7[Ab]IP IVKA(Cdk2)[32P-ATP] is detectable
    *** cells: hFibros in BMS
    *** comment: unaffected by addition of rCdkn1a to kinase reaction
    *** comment: unaffected by addition of rCdkn1b to kinase reaction
    *** source: 7629134-Fig-1b
  *** Cdk7[Ab]IP IVKA(Cdk6)[32P-ATP] is detectable
    *** cells: hFibros in BMS
    *** comment: inhibited by addition of rCdkn1c + rCyclinD1 to kinase reaction
    *** source: 7629134-Fig-4
  *** Cdk7[Ab]IP IVKA(Rb1)[32P-ATP] is detectable
    *** cells: hFibros in BMS
    *** comment: inhibited by addition of rCdkn1c + rCyclinD1 to kinase reaction
    *** source: 7629134-Fig-4
  *** Cdk8[Ab] snaggedby[WB] rElk1(307-428){phos}[Gal4-DBD-G5TATA] is detectable
    *** cells: mESCs in BMS "nuclear extracts"
    *** inhibited by: rElk1(307-428) [substitution]
    *** source: 14506297-Fig-3
  *** Cdk8[Ab] snaggedby[WB] rElk1(307-428){phos}[Gal4-DBD-G5TATA] is detectable
    *** cells: mESCs in BMS "nuclear extracts"
    *** reqs: Med23 [KO]
    *** source: 14506297-Fig-3
  *** Cdk8[Ab] snaggedby[WB] rElk1(TAD){phos}[Gal4-DBD-G5TATA] is detectable
    *** cells: mESCs in BMS "nuclear extracts"
    *** reqs: Med23 [KO]
    *** inhibited by: rElk1(TAD) [substitution]
    *** comment: rElk1(TAD) was phosed by Erk2{act}
    *** source: 11934987-Fig-3d
*** Cdkn1a--
  *** Cdkn1a-gene mRNA[RTPCR] is detectable
    *** cells: mEFs in BMS
    *** reqs: Egr1 [KO]
    *** source: 15958557-Fig-1
  *** Cdkn1a-gene mRNA[RTPCR] is detectable
    *** cells: mSpBCs in BMS "treated with anti-Cd40 (24 hr)"
    *** unaffected by: kMekk1(1-1188)"del-kinase-domain" [addition]
    *** source: 17143273-Fig-6c
  *** Cdkn1a-gene mRNA[RTPCR] is increased itao Cop1 [RNAi]
    *** cells: U2OS in BMS
    *** source: 15103385-Fig-3a
  *** Cdkn1a-gene mRNA[RTPCR] is increased itao Ppm1a [RNAi]
    *** cells: HACAT in BMS
    *** unaffected by: SB202190 [addition]
    *** unaffected by: LY294002 [addition]
    *** unaffected by: SB216763 [addition]
    *** source: 16751101-Fig-5e
  *** Cdkn1a-gene mRNA[RTPCR] is increased itpo xSetd7
    *** cells: H1299<Tp53~null><xTp53> in BMS
    *** reqs: xTp53 [omission]
    *** source: 15525938-Fig-S4
  *** Cdkn1a-gene mRNA[RTPCR] is increased itpo xSetd7
    *** cells: U2OS in BMS
    *** source: 15525938-Fig-4b
  *** Cdkn1a-gene promo-reporter[CAT] is increased itpo xAsk1
    *** cells: H1299<Tp53~null> in BMS
    *** source: 10581258-Fig-2d
  *** Cdkn1a-gene promo-reporter[CAT] is increased itpo xAsk1
    *** cells: MCF7 in BMS
    *** source: 10581258-Fig-1d
  *** Cdkn1a-gene promo-reporter[CAT] is increased itpo xJnk1
    *** cells: MCF7 in BMS
    *** source: 10581258-Fig-1d
  *** Cdkn1a-gene promo-reporter[CAT] is increased itpo xMekk1
    *** cells: H1299<Tp53~null> in BMS
    *** source: 10581258-Fig-2d
  *** Cdkn1a-gene promo-reporter[CAT] is increased itpo xMekk1
    *** cells: MCF7 in BMS
    *** source: 10581258-Fig-1d
  *** Cdkn1a-gene promo-reporter[CAT] is increased itpo xMkk4
    *** cells: H1299<Tp53~null> in BMS
    *** source: 10581258-Fig-2d
  *** Cdkn1a-gene promo-reporter[CAT] is increased itpo xMkk4
    *** cells: MCF7 in BMS
    *** source: 10581258-Fig-1d
  *** Cdkn1a-gene promo-reporter[CAT] is increased itpo xP38?
    *** cells: MCF7 in BMS
    *** source: 10581258-Fig-1d
  *** Cdkn1a-gene promo-reporter[CAT] is unchanged itpo xErk2
    *** cells: H1299<Tp53~null> in BMS
    *** source: 10581258-Fig-2d
  *** Cdkn1a-gene promo-reporter[CAT] is unchanged itpo xErk2
    *** cells: MCF7 in BMS
    *** source: 10581258-Fig-1d
  *** Cdkn1a-gene promo-reporter[CAT] is unchanged itpo xJnk1
    *** cells: H1299<Tp53~null> in BMS
    *** source: 10581258-Fig-2d
  *** Cdkn1a-gene promo-reporter[CAT] is unchanged itpo xMek1
    *** cells: H1299<Tp53~null> in BMS
    *** source: 10581258-Fig-2d
  *** Cdkn1a-gene promo-reporter[CAT] is unchanged itpo xMek1
    *** cells: MCF7 in BMS
    *** source: 10581258-Fig-1d
  *** Cdkn1a-gene promo-reporter[CAT] is unchanged itpo xP38?
    *** cells: H1299<Tp53~null> in BMS
    *** source: 10581258-Fig-2d
  *** Cdkn1a-gene promo-reporter[CAT] is unchanged itpo xRaf1(mnr)"BXB"
    *** cells: H1299<Tp53~null> in BMS
    *** source: 10581258-Fig-2d
  *** Cdkn1a-gene promo-reporter[CAT] is unchanged itpo xRaf1(mnr)"BXB"
    *** cells: MCF7 in BMS
    *** source: 10581258-Fig-1d
  *** Cdkn1a-gene promo-reporter[Luc] is increased itpo xHipk2
    *** cells: H1299<Tp53~null><xTp53> in BMS
    *** source: 11780126-Fig-3c
  *** Cdkn1a-gene promo-reporter[Luc] is increased itpo xZbtb17
    *** cells: HELA in BMS
    *** inhibited by: xGfi1 [addition]
    *** inhibited by: xGfi1(N382S) [addition]
    *** source: 20190815-Fig-4c
  *** Cdkn1a-gene promo-reporter[Luc] is increased itpo xZbtb17
    *** cells: HELA in BMS
    *** inhibited by: xGfi1 [addition]
    *** source: 20190815-Fig-4a
  *** Cdkn1a-gene promo-reporter[Luc] is increased itpo xZbtb17
    *** cells: HELA in BMS
    *** inhibited by: xGfi1 [addition]
    *** source: 20190815-Fig-4b
  *** Cdkn1a-gene promo-reporter[Luc] is increased itpo xZbtb17
    *** cells: HELA in BMS
    *** inhibited by: xGfi1 [addition]
    *** source: 20190815-Fig-6a
  *** Cdkn1a-gene promo-reporter[Luc] is increased itpo xZbtb17
    *** cells: HELA in BMS
    *** inhibited by: xMyc [addition]
    *** source: 20190815-Fig-6a
  *** Cdkn1a[Ab] prot-exp[WB] is decreased itpo xCop1
    *** cells: SAOS2<xTp53> in BMS
    *** partially reversed by: xCop1(S387A) [substitution]
    *** reversed by: xCop1(S387D) [substitution]
    *** source: 16931761-Fig-4e
  *** Cdkn1a[Ab] prot-exp[WB] is detectable-but unchanged itpo xP14Arf
    *** cells: H1299<Tp53~null> in BMS
    *** source: 9724636-Fig-7b
  *** Cdkn1a[Ab] prot-exp[WB] is increased itao Cop1 [RNAi]
    *** cells: BJ in BMS
    *** source: 15103385-Fig-4c
  *** Cdkn1a[Ab] prot-exp[WB] is increased itao Cop1 [RNAi]
    *** cells: U2OS in BMS
    *** source: 15103385-Fig-3a
  *** Cdkn1a[Ab] prot-exp[WB] is increased itao Cop1 [RNAi]
    *** cells: U2OS in BMS
    *** source: 15103385-Fig-4c
  *** Cdkn1a[Ab] prot-exp[WB] is increased itao Cop1 [RNAi]
    *** cells: U2OS in BMS
    *** source: 15989956-Fig-8a
  *** Cdkn1a[Ab] prot-exp[WB] is increased itao Fbxo11 [RNAi]
    *** cells: U2OS in BMS
    *** source: 17098746-Fig-6b
  *** Cdkn1a[Ab] prot-exp[WB] is increased itao Gfi1 [RNAi]
    *** cells: BAF3 in BMS
    *** source: 20190815-Fig-4d
  *** Cdkn1a[Ab] prot-exp[WB] is increased itao Gfi1 [RNAi]
    *** cells: HL60 in BMS
    *** source: 20190815-Fig-4d
  *** Cdkn1a[Ab] prot-exp[WB] is increased itao Gfi1 [RNAi]
    *** cells: TF1 in BMS
    *** source: 20190815-Fig-4d
  *** Cdkn1a[Ab] prot-exp[WB] is increased itao Huwe1 [RNAi]
    *** cells: A549 in BMS
    *** source: 15989956-Fig-S7
  *** Cdkn1a[Ab] prot-exp[WB] is increased itao Huwe1 [RNAi]
    *** cells: HCT116 in BMS
    *** reqs: Tp53 [KO]
    *** source: 15989956-Fig-5e
  *** Cdkn1a[Ab] prot-exp[WB] is increased itao Huwe1 [RNAi]
    *** cells: hFibros in BMS
    *** source: 15989956-Fig-S8
  *** Cdkn1a[Ab] prot-exp[WB] is increased itao Huwe1 [RNAi]
    *** cells: MCF7 in BMS
    *** source: 15989956-Fig-S7
  *** Cdkn1a[Ab] prot-exp[WB] is increased itao Huwe1 [RNAi]
    *** cells: U2OS in BMS
    *** source: 15989956-Fig-5a
  *** Cdkn1a[Ab] prot-exp[WB] is increased itao Huwe1 [RNAi]
    *** cells: U2OS in BMS
    *** source: 15989956-Fig-8a
  *** Cdkn1a[Ab] prot-exp[WB] is increased itao Huwe1 [RNAi]
    *** cells: U2OS in BMS
    *** source: 15989956-Fig-S4d
  *** Cdkn1a[Ab] prot-exp[WB] is increased itao Mdm2 [RNAi]
    *** cells: BJ in BMS
    *** source: 15103385-Fig-4c
  *** Cdkn1a[Ab] prot-exp[WB] is increased itao Mdm2 [RNAi]
    *** cells: MCF7 in BMS
    *** source: 12963717-Fig-3a
  *** Cdkn1a[Ab] prot-exp[WB] is increased itao Mdm2 [RNAi]
    *** cells: U2OS in BMS
    *** source: 15103385-Fig-4c
  *** Cdkn1a[Ab] prot-exp[WB] is increased itao Mdm2 [RNAi]
    *** cells: U2OS in BMS
    *** source: 15989956-Fig-8a
  *** Cdkn1a[Ab] prot-exp[WB] is increased itao Mdm4 [RNAi]
    *** cells: MCF7 in BMS
    *** source: 12963717-Fig-2b
  *** Cdkn1a[Ab] prot-exp[WB] is increased itao Mdm4 [RNAi]
    *** cells: MCF7 in BMS
    *** source: 12963717-Fig-3a
  *** Cdkn1a[Ab] prot-exp[WB] is increased itao Pdpk1 [RNAi]
    *** cells: HACAT in BMS "containing Tgfb1"
    *** source: 17327236-Fig-7d
  *** Cdkn1a[Ab] prot-exp[WB] is increased itao Pdpk1 [RNAi]
    *** cells: HELA in BMS "containing Tgfb1"
    *** source: 17327236-Fig-7d
  *** Cdkn1a[Ab] prot-exp[WB] is increased itao Pirh2 [RNAi]
    *** cells: BJ in BMS
    *** source: 15103385-Fig-4c
  *** Cdkn1a[Ab] prot-exp[WB] is increased itao Pirh2 [RNAi]
    *** cells: U2OS in BMS
    *** source: 15103385-Fig-4c
  *** Cdkn1a[Ab] prot-exp[WB] is increased itao Pirh2 [RNAi]
    *** cells: U2OS in BMS
    *** source: 15989956-Fig-8a
  *** Cdkn1a[Ab] prot-exp[WB] is increased itao Smad2 [RNAi]
    *** cells: PANC1 in BMS
    *** source: 21624123-Fig-S1a
  *** Cdkn1a[Ab] prot-exp[WB] is increased itpo xCdk5
    *** cells: SHSY5Y in BMS
    *** source: 12064478-Fig-3
  *** Cdkn1a[Ab] prot-exp[WB] is increased itpo xCdk5r1{p25}
    *** cells: SHSY5Y in BMS
    *** source: 12064478-Fig-3
  *** Cdkn1a[Ab] prot-exp[WB] is increased itpo xHipk2
    *** cells: U2OS in BMS
    *** enhanced by: xTp53 [addition]
    *** source: 11740489-Fig-7e
  *** Cdkn1a[Ab] prot-exp[WB] is increased itpo xMkk7(mnr)"CA"
    *** cells: H1299<Tp53~null><xTp53> in BMS
    *** inhibited by: xDusp10 [addition]
    *** source: 11283254-Fig-5b
  *** Cdkn1a[Ab] prot-exp[WB] is increased itpo xMkk7(mnr)"CA"
    *** cells: H1299<Tp53~null><xTp53> in BMS
    *** inhibited by: xTp53(T81A) [substitution]
    *** source: 11283254-Fig-5b
  *** Cdkn1a[Ab] prot-exp[WB] is increased itpo xP14Arf
    *** cells: MCF7 in BMS
    *** reversed by: E6!Hpv16 [addition]
    *** source: 9724636-Fig-7d
  *** Cdkn1a[Ab] prot-exp[WB] is increased itpo xP14Arf
    *** cells: MCF7 in BMS
    *** source: 9724636-Fig-7b
  *** Cdkn1a[Ab] prot-exp[WB] is increased itpo xP14Arf
    *** cells: U2OS in BMS
    *** source: 9724636-Fig-4
  *** Cdkn1a[Ab] prot-exp[WB] is increased itpo xP14Arf
    *** cells: U2OS in BMS
    *** source: 15989956-Fig-S13
  *** Cdkn1a[Ab] prot-exp[WB] is increased itpo xPin1
    *** cells: U2OS in BMS
    *** source: 12397361-Fig-S2b
  *** Cdkn1a[Ab] prot-exp[WB] is increased itpo xRac1(S17N)"DN"
    *** cells: PANC1 in BMS
    *** source: 21624123-Fig-3b
  *** Cdkn1a[Ab] prot-exp[WB] is unchanged itao Mdm2 [RNAi]
    *** cells: U2OS in BMS
    *** source: 15989956-Fig-S4a
  *** Cdkn1a[Ab] prot-exp[WB] is unchanged itao Smad3 [RNAi]
    *** cells: PANC1 in BMS
    *** source: 21624123-Fig-S1a
  *** Cdkn1a[Ab] prot-exp[WB] is unchanged itpo xCdkn2a
    *** cells: U2OS in BMS
    *** source: 9724636-Fig-4
  *** Cdkn1a[Ab] prot-exp[WB] is unchanged itpo xP14Arf
    *** cells: SAOS2<Tp53~null><Rb1~null> in BMS
    *** source: 9724636-Fig-7b
  *** Cdkn1a[Ab] prot-exp[WB] is unchanged itpo xPin1
    *** cells: U2OS in BMS
    *** source: 12397361-Fig-3a
  *** xCdkn1a[Ab] snaggedby[WB] rCyclinA?[GST] is detectable
    *** cells: Ecoli<xCdkn1a> in BMS
    *** enhanced by: rCdk2 [addition]
    *** source: 8756624-Fig-2a
  *** xCdkn1a[Ab] snaggedby[WB] rCyclinA?[GST] is undetectable
    *** cells: Ecoli<xCdkn1a> in BMS
    *** source: 8756624-Fig-1a
  *** xCdkn1a[Ab] snaggedby[WB] rCyclinB?[GST] is undetectable
    *** cells: Ecoli<xCdkn1a> in BMS
    *** source: 8756624-Fig-1a
  *** xCdkn1a[Ab] snaggedby[WB] rCyclinD1[GST] is undetectable
    *** cells: Ecoli<xCdkn1a> in BMS
    *** source: 8756624-Fig-1a
  *** xCdkn1a[Ab] snaggedby[WB] rCyclinD2[GST] is undetectable
    *** cells: Ecoli<xCdkn1a> in BMS
    *** source: 8756624-Fig-1a
  *** xCdkn1a[Ab] snaggedby[WB] rCyclinD3[GST] is undetectable
    *** cells: Ecoli<xCdkn1a> in BMS
    *** source: 8756624-Fig-1a
  *** xCdkn1a[Ab] snaggedby[WB] rCyclinE?[GST] is detectable
    *** cells: Ecoli<xCdkn1a> in BMS
    *** source: 8756624-Fig-1a
  *** xCdkn1a[Ab] snaggedby[WB] rCyclinE?[GST] is detectable
    *** cells: Ecoli<xCdkn1a> in BMS
    *** unaffected by: rCdk2 [addition]
    *** source: 8756624-Fig-2a
  *** xCdkn1a[Ab] snaggedby[WB] rCyclinE?[GST] is detectable
    *** cells: Ecoli<xCdkn1a> in BMS
    *** unaffected by: rCyclinE?(1-127) [substitution]
    *** unaffected by: rCyclinE?(1-216) [substitution]
    *** unaffected by: rCyclinE?(1-326) [substitution]
    *** unaffected by: rCyclinE?(1-334) [substitution]
    *** source: 8756624-Fig-1d
  *** Cdkn1b-gene mRNA[RTPCR] is detectable
    *** cells: HELA in BMS
    *** does not req: Arrb2 [RNAi]
    *** unaffected by: xArrb2 [addition]
    *** source: 16325578-Fig-2a
  *** Cdkn1b-gene mRNA[RTPCR] is detectable
    *** cells: HELA in BMS
    *** partially reqs: Arrb1 [RNAi]
    *** enhanced by: xArrb1 [addition]
    *** unaffected by: xArrb1(Q394L) [addition]
    *** source: 16325578-Fig-2a
  *** Cdkn1b-gene mRNA[RTPCR] is detectable
    *** cells: HELA in BMS
    *** partially reqs: Arrb1 [RNAi]
    *** enhanced by: xArrb1 [addition]
    *** unaffected by: xArrb1(Q394L) [addition]
    *** source: 16325578-Fig-6a
  *** Cdkn1b-gene mRNA[RTPCR] is increased itpo xArrb1
    *** cells: mEFs<Arrb1~null><Arrb2~null> in BMS
    *** unaffected by: xArrb1(Q394L) [substitution]
    *** source: 16325578-Fig-2b
  *** Cdkn1b-gene mRNA[RTPCR] is increased itpo xEp300
    *** cells: HELA in BMS
    *** inhibited by: xEp300(mnr)"DN" [substitution]
    *** source: 16325578-Fig-6a
  *** Cdkn1b-gene mRNA[RTPCR] is increased itpo xEp300
    *** cells: mEFs<Arrb1~null><Arrb2~null> in BMS
    *** inhibited by: xEp300(mnr)"DN" [substitution]
    *** source: 16325578-Fig-6b
  *** Cdkn1b-gene mRNA[RTPCR] is unchanged itpo xArrb2
    *** cells: mEFs<Arrb1~null><Arrb2~null> in BMS
    *** source: 16325578-Fig-2b
  *** Cdkn1b[Ab] prot-exp[WB] is detectable
    *** cells: HELA in BMS
    *** does not req: Arrb2 [RNAi]
    *** unaffected by: xArrb2 [addition]
    *** source: 16325578-Fig-2a
  *** Cdkn1b[Ab] prot-exp[WB] is detectable
    *** cells: HELA in BMS
    *** partially reqs: Arrb1 [RNAi]
    *** enhanced by: xArrb1 [addition]
    *** unaffected by: xArrb1(Q394L) [addition]
    *** source: 16325578-Fig-2a
  *** Cdkn1b[Ab] prot-exp[WB] is detectable
    *** cells: HELA in BMS
    *** unaffected by: Fbxw7 [RNAi]
    *** source: 15103331-Fig-4b
  *** Cdkn1b[Ab] prot-exp[WB] is detectable
    *** cells: mSpCs in BMS
    *** does not req: Stat5a or Stat5b [DKO]
    *** source: 10072077-Fig-6a
  *** Cdkn1b[Ab] prot-exp[WB] is increased itao Skp2 [KO]
    *** cells: mESCs in BMS
    *** source: 15103331-Fig-5c
  *** Cdkn1b[Ab] prot-exp[WB] is increased itao Skp2 [RNAi]
    *** cells: HELA in BMS
    *** source: 15103331-Fig-4b
  *** Cdkn1b[Ab] prot-exp[WB] is increased itpo xArrb1
    *** cells: mEFs<Arrb1~null><Arrb2~null> in BMS
    *** unaffected by: xArrb1(Q394L) [substitution]
    *** source: 16325578-Fig-2b
  *** Cdkn1b[Ab] prot-exp[WB] is unchanged itpo xArrb2
    *** cells: mEFs<Arrb1~null><Arrb2~null> in BMS
    *** source: 16325578-Fig-2b
  *** xCdkn1b[Ab] snaggedby[WB] rCyclinA?[GST] is detectable
    *** cells: Ecoli<xCdkn1b> in BMS
    *** source: 8756624-Fig-1b
  *** xCdkn1b[Ab] snaggedby[WB] rCyclinB?[GST] is detectable
    *** cells: Ecoli<xCdkn1b> in BMS
    *** source: 8756624-Fig-1b
  *** xCdkn1b[Ab] snaggedby[WB] rCyclinD1[GST] is undetectable
    *** cells: Ecoli<xCdkn1b> in BMS
    *** source: 8756624-Fig-1b
  *** xCdkn1b[Ab] snaggedby[WB] rCyclinD2[GST] is undetectable
    *** cells: Ecoli<xCdkn1b> in BMS
    *** source: 8756624-Fig-1b
  *** xCdkn1b[Ab] snaggedby[WB] rCyclinE?[GST] is detectable
    *** cells: Ecoli<xCdkn1b> in BMS
    *** source: 8756624-Fig-1b
  *** Cdkn1b[Ab]IP prot-stability[35S-pulse-chase] is increased itpo xTsc2
    *** cells: HELA in BMS
    *** reversed by: xTsc2(S939D/S981D/S993D/S1130D/S1132D/S1462D/S1798D) [substitution]
    *** reversed by: xAkt1(myr) [addition]
    *** source: 12167664-Fig-4a
  *** Cdkn1b[phosAb] phos(T198)[phosAb] is detectable
    *** cells: mEFs in BMS
    *** unaffected by: LY294002 [addition]
    *** unaffected by: U0126 [addition]
    *** source: 17237771(D)
*** Cdkn2b--
  *** Cdkn2b-gene mRNA[Northern] is increased itpo xSmad3
    *** cells: mEFs<Smad3~null> in BMS
    *** enhanced by: xSmad3(T8V) [substitution]
    *** enhanced by: xSmad3(T179V) [substitution]
    *** enhanced by: xSmad3(S213A) [substitution]
    *** enhanced by: xSmad3(T8V/T179V/S213A) [substitution]
    *** source: 15241418-Fig-4e
  *** Cdkn2b-gene mRNA[RTPCR] is increased itao Ppm1a [RNAi]
    *** cells: HACAT in BMS
    *** source: 16751101-Fig-5b
  *** Cdkn2b-gene promo-reporter[Luc] is increased itao Cdk2 [RNAi]
    *** cells: HEPG2 in BMS
    *** source: 15241418-Fig-3c
  *** Cdkn2b-gene promo-reporter[Luc] is increased itao Cdk4 [RNAi]
    *** cells: HEPG2 in BMS
    *** source: 15241418-Fig-3c
  *** Cdkn2b-gene promo-reporter[Luc] is increased itao Ppm1a [RNAi]
    *** cells: HACAT in BMS
    *** source: 16751101-Fig-5c
  *** Cdkn2b-gene promo-reporter[Luc] is increased itpo xSmad3
    *** cells: RGM1 in BMLS
    *** unaffected by: xSmad3(T179V/S204A/S208A/S213A) [substitution]
    *** inhibited by: xSmad3(S416A/S422A/S425A) [substitution]
    *** source: 15326485-Fig-9a
  *** xCebpa[Gal4-DBD] Gal4-reporter[Luc] is unchanged itao Hdac2 [RNAi]
    *** cells: HEK293 in BMS
    *** source: 14992729-Fig-2e
*** Cfl1--
  *** xCfl1[tAb]IP phos[32Pi] is detectable
    *** cells: COS7 in BMS
    *** inhibited by: xRac1(T17N) [addition]
    *** source: 10436159-Fig-3a
  *** xCfl1[tAb]IP phos[32Pi] is increased itpo xLimk2
    *** cells: COS7 in BMS
    *** source: 10436159-Fig-1c
  *** xCfl1[tAb]IP phos[32Pi] is increased itpo xRhoa(G12V)"CA"
    *** cells: COS7<xRac1(T17N)> in BMS
    *** source: 10436159-Fig-3a
  *** xCfl1[tAb]IP phos[32Pi] is increased itpo xRock1(mnr)"CA"
    *** cells: COS7 in BMS
    *** source: 10436159-Fig-1c
*** Chek1--
  *** rChek1[32P] IVKA(auto)[32P-ATP] is detectable
    *** cells: none
    *** inhibited by: rChek1(D130A)"KD" [substitution]
    *** source: 10673501-Fig-2b
  *** Chek1[phosAb] phos(S345)[phosAb] is detectable
    *** cells: NotReported in BMS
    *** reqs: Atr [KO]
    *** source: 16461339-Fig-1d
*** Chek2--
  *** xChek2[XFP] locatedin(nucleus)[IHC] is detectable
    *** cells: HELA<xChek2> in BMS
    *** source: 10097108-Fig-2c
  *** xChfr[tAb] locatedin(subnuclear-bodies)[IHC] is undetectable
    *** cells: HEK293T<xChfr> in BMS "treated with IR for 6 hr"
    *** comment: does not colocalize with H2ax{phos(S140)}[phosAb]
    *** source: 18001825-Fig-1a
  *** xChfr[tAb] snaggedby[WB] rH2ax(mnr){phos}[SBP] is detectable
    *** cells: HEK293T<xChfr> in BMS
    *** source: 18001825-Fig-S2e
*** Ciap1--
  *** Ciap1[Ab] copptby[WB] Tradd[Ab] is undetectable
    *** cells: HELA in BMS
    *** unaffected by: Tnf (5 min) [stim]
    *** source: 8943045-Fig-5
  *** Ciap1[Ab] copptby[WB] Traf1[Ab] is undetectable
    *** cells: HELA in BMS
    *** unaffected by: Tnf (5 min) [stim]
    *** source: 8943045-Fig-5
  *** xCiap1[tAb] copptby[WB] xTgfbR1[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 11356828-Fig-3a
*** Ciap2--
  *** Ciap2-gene promo-reporter[Luc] is increased itpo xTnfR1
    *** cells: HEK293 in BMS
    *** unaffected by: xTpl2(K167M) [addition]
    *** source: 15670770-Fig-1d
  *** Ciap2-gene promo-reporter[Luc] is increased itpo xTraf2
    *** cells: HEK293 in BMS
    *** inhibited by: xTpl2(K167M) [addition]
    *** source: 15670770-Fig-2f
  *** Ciap2-gene promo-reporter[Luc] is increased itpo xTraf6
    *** cells: HEK293 in BMS
    *** inhibited by: xTpl2(K167M) [addition]
    *** source: 15670770-Fig-2f
  *** Ciap2[Ab] snaggedby[WB] rMyd88[GST] is detectable
    *** cells: RAW2647 in BMS
    *** does not req: Traf6 [RNAi]
    *** does not req: Traf3 [RNAi]
    *** source: 19898473-Fig-S3b
  *** Ciap2[Ab] snaggedby[WB] rTrif[GST] is undetectable
    *** cells: RAW2647 in BMS
    *** source: 19898473-Fig-S3b
  *** xCiap2[tAb] copptby[WB] xTgfbR1[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 11356828-Fig-3a
  *** xCiap2[tAb]IP ubiq[K63UbAb] is increased itpo xTraf2
    *** cells: HEK293T<xCiap2> in BMS
    *** inhibited by: xTraf2(mnr)"delN" [substitution]
    *** source: 18997792-Fig-6e
*** Cin85--
  *** xCin85[Ab]IP ubiq[tUbAb] is increased itpo xNedd4
    *** cells: HEK293<xEgfR><xCin85><xUbiq> in BMLS
    *** source: 12218189(D)
*** Cish--
  *** xCish[Ab] copptby[WB] xCsf2Rb[Ab] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xJak1 [addition]
    *** source: 10514520-Fig-5
  *** xCish[Ab] copptby[WB] xIL2Rb[Ab] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xCish(1-82)"NT" [substitution]
    *** unaffected by: xCish(1-177)"dCT" [substitution]
    *** source: 10514520-Fig-4b
  *** xCish[Ab] copptby[WB] xIL2Rb[Ab] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xIL2Rb(del(312-383))"delA" [substitution]
    *** partially inhibited by: xIL2Rb(del(266-323))"delB" [substitution]
    *** source: 10514520-Fig-3b
  *** xCish[Ab] copptby[WB] xIL2Rb[Ab] is detectable
    *** cells: HEK293T in BMS
    *** source: 10514520-Fig-5
  *** xCish[Ab] copptby[WB] xIL2Rb[Ab] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xCish(R107K) [substitution]
    *** source: 10514520-Fig-4c
  *** xCish[Ab] copptby[WB] xIL2Rb[Ab] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xIL2Rb(1-379) [substitution]
    *** unaffected by: xIL2Rb(1-371) [substitution]
    *** unaffected by: xIL2Rb(1-362) [substitution]
    *** unaffected by: xIL2Rb(1-350) [substitution]
    *** inhibited by: xIL2Rb(1-330) [substitution]
    *** source: 10514520-Fig-3c
  *** xCish[Ab] copptby[WB] xIL2Rb[Ab] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xIL2Rb(Y338F/Y355F/Y358F/Y361F/Y392F/Y510F) [substitution]
    *** source: 10514520-Fig-4c
  *** Col1[Ab] prot-exp[WB] is increased itao Smad2 [KO]
    *** cells: mEFs in BMS
    *** source: 20595680-Fig-5a
  *** Col1[Ab] prot-exp[WB] is unchanged itao Smad2 [KO]
    *** cells: mEFs in BMS
    *** source: 20595680-Fig-5b
  *** Col1a1-gene mRNA[RTPCR] is increased itao Smad2 [KO]
    *** cells: mEFs in BMS
    *** source: 20595680-Fig-4a
  *** Col1a1-gene mRNA[RTPCR] is increased itao Smad2 [KO]
    *** cells: mEFs in BMS
    *** source: 20595680-Fig-4b
  *** Col1a1-gene mRNA[RTPCR] is unchanged itao Smad2 [RNAi]
    *** cells: mTECs in BMS
    *** source: 20595680-Fig-4c
  *** Col1a1-gene promo-reporter[Luc] is decreased itpo xErbin
    *** cells: AKR2B in BMLS "treated with Tgfb1 for 45 min"
    *** reqs: Merlin [RNAi]
    *** source: 19289088-Fig-4d
  *** Col3[Ab] prot-exp[WB] is increased itao Smad2 [KO]
    *** cells: mEFs in BMS
    *** source: 20595680-Fig-5a
  *** Col3[Ab] prot-exp[WB] is increased itao Smad2 [KO]
    *** cells: mEFs in BMS
    *** source: 20595680-Fig-5b
  *** Col3a1-gene mRNA[RTPCR] is increased itao Smad2 [KO]
    *** cells: mEFs in BMS
    *** source: 20595680-Fig-4a
  *** Col3a1-gene mRNA[RTPCR] is increased itao Smad2 [KO]
    *** cells: mEFs in BMS
    *** source: 20595680-Fig-4b
  *** Col3a1-gene mRNA[RTPCR] is unchanged itao Smad2 [RNAi]
    *** cells: mTECs in BMS
    *** source: 20595680-Fig-4c
  *** Col11a1-gene mRNA[RTPCR] is increased itao Egr1 [KO]
    *** cells: mEFs in BMS
    *** source: 15958557-Fig-1
  *** Cop1-gene mRNA[RTPCR] is increased itpo xTp53
    *** cells: H1299<Tp53~null> in BMS
    *** inhibited by: xTp53(R175H) [substitution]
    *** source: 15103385-Fig-5c
  *** rCop1(377-400)[32P] phos[32P-ATP] is increased by Atm[Ab]IP
    *** cells: none
    *** IPfrom: GM3490 in BMS "treated with IR for 30 min"
    *** inhibited by: rCop1(377-400/S387A) [substitution]
    *** source: 16931761-Fig-1e
  *** rCop1[32P] phos[32P-ATP] is increased by Atm[Ab]IP
    *** cells: none
    *** IPfrom: NotReported in BMS
    *** inhibited by: rCop1(S387A) [substitution]
    *** source: 16931761-Fig-S7
  *** xCop1[Ab] prot-exp[WB] is decreased itpo xAtm
    *** cells: SAOS2<xCop1> in BMS
    *** reversed by: MG132 [addition]
    *** source: 16931761-Fig-2c
  *** xCop1[Ab] prot-exp[WB] is decreased itpo xAtm
    *** cells: SAOS2<xCop1> in BMS
    *** reversed by: xAtm(mnr)"KD" [substitution]
    *** source: 16931761-Fig-2a
  *** xCop1[Ab] prot-exp[WB] is decreased itpo xAtm
    *** cells: SAOS2<xCop1> in BMS
    *** reversed by: xAtm(mnr)"KD" [substitution]
    *** source: 16931761-Fig-2f
  *** xCop1[Ab] prot-exp[WB] is decreased itpo xAtm
    *** cells: SAOS2<xCop1> in BMS
    *** reversed by: xCop1(C136S/C139S) [substitution]
    *** source: 16931761-Fig-2f
  *** xCop1[Ab] prot-exp[WB] is decreased itpo xAtm
    *** cells: SAOS2<xCop1> in BMS
    *** reversed by: xCop1(S387A) [substitution]
    *** source: 16931761-Fig-2b
  *** Cop1[Ab] prot-exp[WB] is increased itpo xTp53
    *** cells: H1299<Tp53~null> in BMS
    *** inhibited by: xTp53(R175H) [substitution]
    *** source: 15103385-Fig-5d
  *** rCop1[Ab]IP ubiq[tUbAb] is increased by (rUbe2d2 + rUbe1 + rUbiq)
    *** cells: none
    *** unaffected by: rCop1(S387A) [substitution]
    *** enhanced by: rCop1(S387D) [substitution]
    *** source: 16931761-Fig-2g
  *** xCop1[tAb] ubiq[tUbAb] is increased itpo xAtm
    *** cells: H1299<xCop1><xUbiq> in BMS "treated with proteosome inhibitor for 4 hr"
    *** inhibited by: xAtm(mnr)"KD" [substitution]
    *** source: 16931761-Fig-2d
  *** xCop1[tAb] ubiq[tUbAb] is increased itpo xAtm
    *** cells: H1299<xCop1><xUbiq> in BMS "treated with proteosome inhibitor for 4 hr"
    *** inhibited by: xCop1(S387A) [substitution]
    *** source: 16931761-Fig-2e
  *** xCop1[tAb]IP phos(S387)[phosAb] is increased itpo xAtm
    *** cells: HEK293T<xCop1> in BMS
    *** inhibited by: xAtm(mnr)"KD" [substitution]
    *** source: 16931761-Fig-S10
  *** xCop1[tAb]IP ubiq[tUbAb] is increased by (rUbe2d2 + rUbe1 + rUbiq)
    *** cells: none
    *** IPfrom: HEK293T<xCop1> in BMS
    *** enhanced by: xCop1(S387D) [substitution]
    *** inhibited by: xCop1(C136S/C139S) [substitution]
    *** source: 16931761-Fig-S13
  *** xCradd[tAb] copptby[WB] xNod1[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 10329646(D)
  *** CRE-reporter[Luc] is increased itpo xCreb1
    *** cells: HEK293T in BMS
    *** enhanced by: xCreb1(T100A/S111A/S121A) [substitution]
    *** source: 15073328-Fig-4b
*** Creb1--
  *** xCreb1(1-261)[Gal4-DBD] Gal4-reporter[CAT] is increased itpo xP38a
    *** cells: SKNMC in BMS
    *** inhibited by: xCreb1(1-261/S133A) [substitution]
    *** source: 8887554-Fig-8a
  *** rCreb1[14C] acetyl[14C-acetyl-CoA] is unchanged by rEp300(1195-1810)
    *** cells: none
    *** source: 9288740-Fig-1a
  *** rCreb1[32P] phos[32P-ATP] is unchanged by rAkt1
    *** cells: none
    *** source: 11500364-Fig-3a
  *** rCreb1[32P] phos[32P-ATP] is unchanged by rAkt1(mnr)
    *** cells: none
    *** source: 11297520-Fig-1a
  *** rCreb1[32P] phos[32P-ATP] is unchanged by rS6k1
    *** cells: none
    *** source: 11500364-Fig-3a
  *** rCreb1[32P] phos[32P-ATP] is unchanged by xRsk1[GST]IP
    *** cells: none
    *** comment: xRsk1[GST]IP is from PMA stimuluated HEH293
    *** source: 11500364-Fig-3a
  *** rCreb1[32P] phos[32P-ATP] is unchanged by xRsk1[GST]IP
    *** cells: none
    *** comment: xRsk1[GST]IP is from PMA stimuluated HEK293
    *** source: 11297520-Fig-1a
  *** rCreb1[32P] phos[32P-ATP] is unchanged by xS6k1((1-421)/T412E)[tAb]IP
    *** cells: none
    *** comment: xS6k1((1-421)/T412E)IP is from insect cells and activated in vitro with Pdk1
    *** source: 11297520-Fig-1a
  *** Creb1[Ab] boundto(Cdkn1b-gene)[ChIP] is detectable
    *** cells: HELA in BMS
    *** does not req: Arrb1 [RNAi]
    *** unaffected by: xArrb1 [addition]
    *** unaffected by: xArrb1(Q394L) [addition]
    *** source: 16325578-Fig-6d
  *** Creb1[Ab] boundto(Fos-gene)[ChIP] is detectable
    *** cells: HELA in BMS
    *** does not req: Arrb1 [RNAi]
    *** unaffected by: xArrb1 [addition]
    *** unaffected by: xArrb1(Q394L) [addition]
    *** source: 16325578-Fig-6d
  *** Creb1[Ab] boundto(Jun-gene)[ChIP] is detectable
    *** cells: HELA in BMS
    *** does not req: Arrb1 [RNAi]
    *** unaffected by: xArrb1 [addition]
    *** unaffected by: xArrb1(Q394L) [addition]
    *** source: 16325578-Fig-6d
  *** Creb1[Ab] copptby[WB] Arrb1[Ab] is detectable
    *** cells: HELA in BMS
    *** source: 16325578-Fig-6c
  *** xCreb1[Ab] snaggedby[WB] rCbp(587-666)"KIX"[GST] is detectable
    *** cells: HEK293T<xCreb1> in BMS
    *** inhibited by: rCreb1(S133A) [substitution]
    *** source: 15073328-Fig-3a
  *** xCreb1[Gal4-DBD] Gal4-reporter[Luc] is detectable
    *** cells: HEK293T in BMS
    *** enhanced by: xCreb1(T100A/S111A/S121A) [substitution]
    *** inhibited by: xCreb1(S133A) [substitution]
    *** inhibited by: xCreb1(T100A/S111A/S121A/S133A) [substitution]
    *** enhanced by: xCreb1(S111A) [substitution]
    *** enhanced by: xCreb1(S121A) [substitution]
    *** source: 15073328-Fig-8b
  *** xCreb1[Gal4-DBD] Gal4-reporter[Luc] is detectable
    *** cells: HEK293T in BMS
    *** enhanced by: xCreb1(T100A/S111A/S121A) [substitution]
    *** inhibited by: xCreb1(S133A) [substitution]
    *** source: 15073328-Fig-4a
  *** xCreb1[Gal4-DBD] Gal4-reporter[Luc] is detectable
    *** cells: HEK293T in BMS
    *** enhanced by: xCreb1(T100A/S111A/S121A) [substitution]
    *** source: 15073328-Fig-8a
  *** rCreb1[GST] phos[32P-ATP] is unchanged by xRsk1[Ab]IP
    *** cells: none
    *** IPfrom: HEK293<xRsk1> in BMS "treated with PMA for 15 min"
    *** source: 9687510-Fig-8b
  *** rCreb1[GST] phos[32P-ATP] is unchanged by xRsk3[Ab]IP
    *** cells: none
    *** IPfrom: HEK293<xRsk3> in BMS "treated with PMA for 15 min"
    *** source: 9687510-Fig-8b
  *** xCreb1[phosAb] phos(S121)[phosAb] is detectable
    *** cells: HEK293T<xCreb1> in BMS
    *** inhibited by: xCreb1(S121A) [substitution]
    *** source: 15073328-Fig-9b
  *** Creb1[phosAb] phos(S133)[phosAb] is detectable
    *** cells: HEPG2 in BMLS "plated on collagen"
    *** unaffected by: Gefitinib [cotreatment]
    *** partially inhibited by: PD325901 [cotreatment]
    *** partially inhibited by: BMS345541 [cotreatment]
    *** partially inhibited by: PHA818637 [cotreatment]
    *** unaffected by: ZSTK474 [cotreatment]
    *** source: 19953085-Fig-S1
  *** rCreb1[phosAb] phos(S133)[phosAb] is increased by pMapkapk2
    *** cells: none
    *** source: 8887554-Fig-5a
*** Crk--
  *** Crk[Ab] copptby[WB] Bcar1[Ab] is detectable
    *** cells: HEK293 in BMS
    *** enhanced by: xCap [addition]
    *** source: 14657239-Fig-4b
  *** Crk[Ab] copptby[WB] Bcar1[Ab] is increased itpo xSh2d3c(myr)
    *** cells: HEK293 in BMS
    *** source: 15272013-Fig-7a
  *** Crk[Ab] copptby[WB] Bcar1[Ab] is undetectable
    *** cells: RAT1<xEgfR> in BMLS
    *** source: 9325334-Fig-5
  *** Crk[Ab] copptby[WB] Pxn[Ab] is undetectable
    *** cells: 32D in BMS
    *** unaffected by: IL3 (10 min) [stim]
    *** source: 7493940-Fig-2
  *** Crk[Ab] copptby[WB] Pxn[Ab] is undetectable
    *** cells: K562 in BMS
    *** source: 7493940-Fig-2
  *** xCrk[Ab] copptby[WB] xBcar1[Ab] is increased itpo xFak2
    *** cells: HEK293T in BMS
    *** inhibited by: xFak2(Y402F) [substitution]
    *** unaffected by: xFak2(Y881F) [substitution]
    *** inhibited by: xFak2(mnr)"KD" [substitution]
    *** source: 10329689-Fig-5b
  *** Crk[Ab] copptby[WB] xCap[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 14657239-Fig-4b
  *** xCrk[Ab] copptby[WB] xHpk1[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 9891069-Fig-1b
  *** rCrk[phosAb] phos(Y221)[phosAb] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xAbl2 [addition]
    *** source: 15886098-Fig-5b
  *** xCrk[tAb] copptby[WB] xGab1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** partially inhibited by: xGab1(del(241-411)) [substitution]
    *** source: 19350053-Fig-1c
  *** xCrk[tAb] copptby[WB] xGab1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** partially inhibited by: xGab1(Y307F) [substitution]
    *** source: 19350053-Fig-6b
  *** xCrk[tAb] copptby[WB] xGab1[tAb] is detectable
    *** cells: HEK293T<xCrk> in BMS
    *** unaffected by: xCrk(R38V) [substitution]
    *** unaffected by: xCrk(W139L) [substitution]
    *** unaffected by: xCrk(Y221F) [substitution]
    *** source: 19350053-Fig-1c
*** CrkI--
  *** rCrkI[Ab] boundby[WB] rTrip6[GST] is undetectable
    *** cells: none
    *** source: 15988003-Fig-3b
  *** rCrkI[Ab] boundby[WB] rTrip6{phos}[GST] is detectable
    *** cells: none
    *** comment: rTrip6 was phosed by rSrc
    *** inhibited by: rTrip6(Y55F) [substitution]
    *** unaffected by: rTrip6(P58A) [substitution]
    *** source: 15988003-Fig-3b
  *** xCrkI[tAb] copptby[WB] xTrip6[tAb] is detectable
    *** cells: HEK293T<xCrkI><xTrip6><xSrc> in BMLS
    *** inhibited by: xTrip6(Y55F) [substitution]
    *** source: 15988003-Fig-4b
*** CrkL--
  *** CrkL[Ab] copptby[WB] Pxn[Ab] is detectable
    *** cells: K562 in BMS
    *** source: 7493940-Fig-4b
  *** CrkL[Ab] copptby[WB] Pxn[Ab] is undetectable
    *** cells: 32D in BMS
    *** unaffected by: IL3 (10 min) [stim]
    *** source: 7493940-Fig-4b
  *** CrkL[Ab] copptby[WB] RapGef1[Ab] is detectable
    *** cells: PC12 in BMLS
    *** source: 11466412-Fig-3a
  *** CrkL[Ab] copptby[WB] RapGef1[Ab] is detectable
    *** cells: PC12 in BMLS
    *** source: 11466412-Fig-3b
  *** CrkL[Ab] copptby[WB] xGab1[Ab] is detectable
    *** cells: HEK293<xGab2><xPik3r1> in BMS "treated with Hgf + PAO for tnr"
    *** unaffected by: xGab1(116-694) [substitution]
    *** inhibited by: xGab1(del(242-411))"dCrk" [substitution]
    *** partially inhibited by: xGab1(Y448F/Y473F/Y590F)"dPi3k" [substitution]
    *** partially inhibited by: xGab1(Y682F)"dShp2" [substitution]
    *** inhibited by: xGab1(450-694) [substitution]
    *** inhibited by: xGab1((450-694)/Y473F/Y590F) [substitution]
    *** source: 10871282-Fig-4b
  *** xCrkL[Ab] copptby[WB] xHpk1[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 9891069-Fig-1b
  *** CrkL[Ab] Yphos[pYAb-ppt] is detectable
    *** cells: K562 in BMS
    *** source: 7493940-Fig-1
  *** CrkL[Ab]IP Yphos[pYAb] is detectable
    *** cells: PC12 in BMLS
    *** source: 11466412-Fig-3a
  *** CrkL[Ab]IP Yphos[pYAb] is detectable
    *** cells: PC12 in BMLS
    *** source: 11466412-Fig-3b
  *** xCrkL[Ab]IP Yphos[pYAb] is undetectable
    *** cells: 32D in BMS
    *** source: 8978605-Fig-6a
*** Crm1--
  *** xCrm1(566-720)[XFP] locatedin(nucleus)[IHC] is detectable
    *** cells: COS1<xAtf2(342-505)> in BMS
    *** comment: xCrm1(566-720) is dimerized with xAtf2(342-505) [BiFC]
    *** inhibited by: xJun [addition]
    *** inhibited by: xAtf2((342-505)/V405A/L408A/L411A/L413A) [substitution]
    *** source: 16511568-Fig-4e
  *** rCrm1[35S] boundby[WB] rStat1[GST] is detectable
    *** cells: none
    *** comment: reaction contains rRan(Q69L)
    *** unaffected by: rCrm1(1-526) [substitution]
    *** unaffected by: rCrm1(1-448) [substitution]
    *** unaffected by: rCrm1(1-436) [substitution]
    *** inhibited by: rCrm1(1-369) [substitution]
    *** inhibited by: rCrm1(1-315) [substitution]
    *** source: 11080165-Fig-3b
  *** rCrm1[35S] boundby[WB] rStat1[GST] is detectable
    *** cells: none
    *** reqs: rRan(Q69L) [omission]
    *** source: 11080165-Fig-3a
  *** xCrm1[tAb] copptby[WB] xSmurf1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xSmurf1(I638A/L640A)"NES-mut" [substitution]
    *** source: 12519765-Fig-3c
  *** xCrm1[tAb] locatedin(nucleus)[IHC] is detectable
    *** cells: HELA<xSmurf1(I638A/L640A)"NES-mut"> in BMS
    *** source: 12519765-Fig-4b
*** Csf1R--
  *** Csf1R[Ab] copptby[WB] Itgb3[Ab] is detectable
    *** cells: mOLCs in BMS
    *** source: 16600665-Fig-1a,3a
*** Csf2--
  *** Csf2[Ab] secretion[ELISA] is detectable
    *** cells: mSpTh1 in BMS "treated with anti-Cd3 for 24 hr"
    *** does not req: Stat6 [KO]
    *** source: 8624821-Fig-5a
  *** xCsf2Ra[tAb] copptby[WB] Sos12s[Ab] is undetectable
    *** cells: COS in BMS
    *** source: 11003655(D)
  *** xCsf2Rb[Ab]IP Yphos[pYAb] is increased itpo xJak1
    *** cells: HEK293T<xCish> in BMS
    *** source: 10514520-Fig-5
  *** Csk[Ab] copptby[WB] Pxn[Ab] is detectable
    *** cells: MDAMB468 in BMLS
    *** comment: complex can be broken up by rShp2(mnr)"PTPaseDomain" treatment
    *** source: 14665621-Fig-3b
  *** Csk[Ab] copptby[WB] Pxn[Ab] is unchanged itpo xGab1(Y627F/Y659F)
    *** cells: MDAMB468 in BMLS
    *** source: 14665621-Fig-4b
  *** Csk[Ab] copptby[WB] xPag1[tAb] is detectable
    *** cells: COS in BMS
    *** enhanced by: xFyn [addition]
    *** source: 10790433-Fig-8a
  *** Csk[Ab] copptby[WB] xPag1[tAb] is detectable
    *** cells: COS in BMS
    *** inhibited by: xPag1(Y317F) [substitution]
    *** source: 10790433-Fig-7e
  *** Csk[Ab] copptby[WB] xPag1[tAb] is increased itpo xFyn
    *** cells: COS in BMS
    *** source: 10790433-Fig-8a
  *** xCsk[tAb] copptby[WB] Crk[Ab] is detectable
    *** cells: HEK293T in BMS
    *** source: 19350053-Fig-4c
  *** xCsk[tAb] copptby[WB] xPag1[tAb] is increased itpo xFyn
    *** cells: COS1 in BMLS
    *** unaffected by: xFyn(Y528F)"CA" [substitution]
    *** source: 14613929-Fig-3a
*** Csnk1a1--
  *** Csnk1a1[Ab] infraction(nonDRM)[WB] is detectable
    *** cells: HEK293T<xCsnk1g1> in BMS
    *** source: 20053636-Fig-2a
  *** Csnk1a1[Ab] prot-exp[WB] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: Csnk1e [RNAi]
    *** source: 11955436-Fig-6e
  *** xCsnk1a1[tAb] copptby[WB] xIkk1[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 18067272-Fig-2a
  *** xCsnk1a1[tAb] copptby[WB] xIkk2[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 18067272-Fig-2a
  *** xCsnk1a1[tAb] copptby[WB] xMekk3[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 18067272-Fig-2a
  *** xCsnk1a1[tAb] copptby[WB] xNemo[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 18067272-Fig-2a
  *** xCsnk1a1[tAb] copptby[WB] xRipk1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 18067272-Fig-2a
  *** xCsnk1a1[tAb] copptby[WB] xRipk1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 18067272-Fig-2b
  *** xCsnk1a1[tAb] copptby[WB] xRipk1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: Tnf (10 min) [stim]
    *** source: 18067272-Fig-2c
  *** xCsnk1a1[tAb] copptby[WB] xRipk2[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 18067272-Fig-2b
  *** xCsnk1a1[tAb] copptby[WB] xRipk3[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 18067272-Fig-2b
  *** xCsnk1a1[tAb] copptby[WB] xTradd[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 18067272-Fig-2a
  *** xCsnk1a1[tAb] copptby[WB] xTraf2[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 18067272-Fig-2a
  *** rCsnk1e IVKA(auto)[32P-ATP] is increased by rPpp1ca
    *** cells: none
    *** source: 9430669-Fig-4a
  *** rCsnk1e IVKA(auto)[32P-ATP] is increased by rPpp2ca
    *** cells: none
    *** source: 9430669-Fig-4a
  *** rCsnk1e IVKA(Ikba)[32P-ATP] is detectable
    *** cells: none
    *** enhanced by: rCsnk1e(1-349) [substitution]
    *** unaffected by: rCsnk1e(1-305) [substitution]
    *** unaffected by: rCsnk1e(1-360) [substitution]
    *** unaffected by: rCsnk1e(S350A/T351A/S354A) [substitution]
    *** source: 10542239-Fig-5
  *** rCsnk1e IVKA(Ikba)[32P-ATP] is detectable
    *** cells: none
    *** enhanced by: rCsnk1e(S323A/T325A/T334A/T337A/S368A/S405A/T407A/S408A) [substitution]
    *** source: 10542239-Fig-7
  *** rCsnk1e IVKA(Ikba)[32P-ATP] is detectable
    *** cells: none
    *** unaffected by: rCsnk1e(1-383) [substitution]
    *** unaffected by: rCsnk1e(1-370) [substitution]
    *** unaffected by: rCsnk1e(1-360) [substitution]
    *** enhanced by: rCsnk1e(1-349) [substitution]
    *** enhanced by: rCsnk1e(1-329) [substitution]
    *** unaffected by: rCsnk1e(1-305) [substitution]
    *** source: 10542239-Fig-4
  *** rCsnk1e IVKA(Ikba)[32P-ATP] is increased by pPP2b
    *** cells: none
    *** source: 9430669-Fig-6a
  *** rCsnk1e IVKA(Ikba)[32P-ATP] is increased by rPpp1ca
    *** cells: none
    *** source: 9430669-Fig-6a
  *** rCsnk1e IVKA(Ikba)[32P-ATP] is increased by rPpp2ca
    *** cells: none
    *** source: 9430669-Fig-6a
  *** rCsnk1e IVKA(SV40TAg)[32P-ATP] is increased by pPpp2cs
    *** cells: none
    *** unaffected by: rCsnk1e(1-383) [substitution]
    *** unaffected by: rCsnk1e(1-370) [substitution]
    *** unaffected by: rCsnk1e(1-360) [substitution]
    *** inhibited by: rCsnk1e(1-349) [substitution]
    *** inhibited by: rCsnk1e(1-329) [substitution]
    *** inhibited by: rCsnk1e(1-319) [substitution]
    *** inhibited by: rCsnk1e(1-305) [substitution]
    *** source: 10542239-Fig-3b
  *** rCsnk1e IVKA(SV40TAg)[32P-ATP] is increased by rPpp1ca
    *** cells: none
    *** source: 9430669-Fig-4a
  *** rCsnk1e IVKA(SV40TAg)[32P-ATP] is increased by rPpp2ca
    *** cells: none
    *** source: 9430669-Fig-4a
*** Csnk1e--
  *** xCsnk1e[Ab] infraction(nonDRM)[WB] is detectable
    *** cells: HEK293T<xCsnk1g1> in BMS
    *** source: 20053636-Fig-2a
  *** Csnk1e[Ab] prot-exp[WB] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: Csnk1a1 [RNAi]
    *** source: 11955436-Fig-6e
  *** Csnk1e[Ab]IP IVKA(Axin1)[32P-ATP] is detectable
    *** cells: HEK293 in BMS
    *** comment: enhanced by treatment of IP with LambdaPPase
    *** source: 14722104-Fig-2a
  *** xCsnk1e[tAb] copptby[WB] xDvl1[tAb] is detectable
    *** cells: COS<xDvl1><xFrat1><xCsnk1e> in BMS
    *** partially inhibited by: xCsnk1(mnr)"KD" [substitution]
    *** source: 12556519-Fig-2c
  *** xCsnk1e[tAb] copptby[WB] xDvl1[tAb] is detectable
    *** cells: COS<xDvl1><xFrat1><xCsnk1e> in BMS
    *** unaffected by: xFrat1(1-185) [substitution]
    *** source: 12556519-Fig-2c
  *** xCsnk1e[tAb] copptby[WB] xFrat1[tAb] is detectable
    *** cells: COS<xDvl1><xFrat1><xCsnk1e> in BMS
    *** partially inhibited by: xCsnk1(mnr)"KD" [substitution]
    *** source: 12556519-Fig-2a
  *** xCsnk1e[tAb] copptby[WB] xFrat1[tAb] is detectable
    *** cells: COS<xDvl1><xFrat1><xCsnk1e> in BMS
    *** partially inhibited by: xDvl1(1-250) [substitution]
    *** partially inhibited by: xDvl1(del(228-250)) [substitution]
    *** partially inhibited by: xDvl1(del(337-695)) [substitution]
    *** unaffected by: xDvl1(1-544) [substitution]
    *** unaffected by: xDvl1(140-695) [substitution]
    *** unaffected by: xDvl1(del(141-227)) [substitution]
    *** unaffected by: xDvl1(del(251-336)) [substitution]
    *** source: 12556519-Fig-2a
  *** xCsnk1e[tAb]IP IVKA(Axin1)[32P-ATP] is detectable
    *** cells: HEK293<xCsnk1e> in BMS
    *** enhanced by: xCsnk1e(S323A/T325A/T334A/T337A/S368A/S405A/T407A/S408A)"MM2" [substitution]
    *** source: 14722104-Fig-3a
  *** xCsnk1e[tAb]IP IVKA(Axin1)[32P-ATP] is detectable
    *** cells: HEK293<xCsnk1e> in BMS
    *** enhanced by: xCsnk1e(S323A/T325A/T334A/T337A/S368A/S405A/T407A/S408A)"MM2" [substitution]
    *** source: 14722104-Fig-3b
  *** xCsnk1e[tAb]IP IVKA(Axin1)[32P-ATP] is increased itpo xPpm1a
    *** cells: HEK293<xCsnk1e> in BMS
    *** source: 14722104-Fig-6c
  *** xCsnk1g1[Ab] infraction(DRM)[WB] is detectable
    *** cells: HEK293T<xCsnk1g1> in BMS
    *** source: 20053636-Fig-2a
  *** xCsnk1g1[tAb] copptby[WB] xCav1[tAb] is detectable
    *** cells: HEK293T<xCsnk1g1><xCav1> in BMS
    *** source: 20053636-Fig-2e
  *** xCsnk1g2[tAb] copptby[WB] xSmad1[tAb] is undetectable
    *** cells: HEK293T<xCsnk1g2><xSmad1> in BMS
    *** source: 18794808-Fig-1b
  *** xCsnk1g2[tAb] copptby[WB] xSmad2[tAb] is undetectable
    *** cells: HEK293T<xCsnk1g2><xSmad2> in BMS
    *** source: 18794808-Fig-1b
  *** xCsnk1g2[tAb] copptby[WB] xSmad4[tAb] is undetectable
    *** cells: HEK293T<xCsnk1g2><xSmad4> in BMS
    *** source: 18794808-Fig-1b
  *** xCsnk1g2[tAb]IP IVKA(Smad3)[32P-ATP] is detectable
    *** cells: HEK293T<xCsnk1g2> in BMS
    *** unaffected by: xCsnk1g2(1-403)"delNLS" [substitution]
    *** unaffected by: xCsnk1g2(C399A/C400A/C401A) [substitution]
    *** unaffected by: xCsnk1g2(1-354)"delC" [substitution]
    *** source: 18794808-Fig-S6b
*** Csnk2--
  *** Csnk2[Ab] copptby[WB] xRela[tAb] is detectable
    *** cells: mEFs<Rela~null><xRela> in BMS
    *** source: 10938077-Fig-1a
  *** rCsnk2a1 boundby[SPR] rAtf1[GST] is detectable
    *** cells: none
    *** enhanced by: rAtf1(214-271) [substitution]
    *** inhibited by: rAtf1(1-214) [substitution]
    *** source: 9685505-Fig-3
*** Csnk2a1--
  *** rCsnk2a1[Ab] boundby[FarWestern] rAtf1(214-271)[GST] is detectable
    *** cells: none
    *** source: 9685505-Fig-4b
  *** rCsnk2a1[Ab] boundby[FarWestern] rAtf2(351-415)[GST] is detectable
    *** cells: none
    *** source: 9685505-Fig-4b
  *** rCsnk2a1[Ab] boundby[FarWestern] rCreb1(268-327)[GST] is detectable
    *** cells: none
    *** source: 9685505-Fig-4b
  *** rCsnk2a1[Ab] boundby[FarWestern] rFos!Rat(139-211)[GST] is detectable
    *** cells: none
    *** source: 9685505-Fig-4b
  *** rCsnk2a1[Ab] boundby[FarWestern] rJun(222-331)[GST] is detectable
    *** cells: none
    *** source: 9685505-Fig-4b
  *** rCsnk2a1[Ab] boundby[WB] rAtf1(214-271)[GST] is detectable
    *** cells: none
    *** partially inhibited by: rAtf1(228-271) [substitution]
    *** inhibited by: rAtf1(240-271) [substitution]
    *** partially inhibited by: rAtf1(214-239) [substitution]
    *** partially inhibited by: rAtf1((214-271)/L248P) [substitution]
    *** source: 9685505-Fig-2c
  *** rCsnk2a1[Ab] boundby[WB] rAtf1(214-271)[GST] is detectable
    *** cells: none
    *** source: 9685505-Fig-4a
  *** rCsnk2a1[Ab] boundby[WB] rAtf1[GST] is detectable
    *** cells: none
    *** inhibited by: rAtf1(1-57) [substitution]
    *** inhibited by: rAtf1(1-141) [substitution]
    *** partially inhibited by: rAtf1(1-214) [substitution]
    *** unaffected by: rAtf1(56-271) [substitution]
    *** unaffected by: rAtf1(del(57-142)) [substitution]
    *** unaffected by: rAtf1(142-271) [substitution]
    *** unaffected by: rAtf1(214-271) [substitution]
    *** source: 9685505-Fig-2a
  *** rCsnk2a1[Ab] boundby[WB] rAtf1[GST] is detectable
    *** cells: none
    *** source: 9685505-Fig-1a
  *** rCsnk2a1[Ab] boundby[WB] rAtf1[GST] is detectable
    *** cells: none
    *** unaffected by: rAtf1(214-271) [substitution]
    *** inhibited by: rAtf1(1-213) [substitution]
    *** source: 9685505-Fig-1b
  *** rCsnk2a1[Ab] boundby[WB] rAtf2(351-415)[GST] is detectable
    *** cells: none
    *** source: 9685505-Fig-4a
  *** rCsnk2a1[Ab] boundby[WB] rCreb1(268-327)[GST] is detectable
    *** cells: none
    *** source: 9685505-Fig-4a
  *** rCsnk2a1[Ab] boundby[WB] rFos!Rat(139-211)[GST] is detectable
    *** cells: none
    *** source: 9685505-Fig-4a
  *** rCsnk2a1[Ab] boundby[WB] rJun(222-331)[GST] is detectable
    *** cells: none
    *** source: 9685505-Fig-4a
  *** rCsnk2a2 boundby[WB] rAtf1[GST] is detectable
    *** cells: none
    *** source: 9685505-Fig-1a
  *** Csnk2as[Ab] copptby[WB] xAtf1[tAb] is detectable
    *** cells: HELA in BMS
    *** source: 9685505-Fig-1c
  *** rCsnk2b boundby[WB] (rAtf1[GST] + rCsnk2a1[GST]) is detectable
    *** cells: none
    *** reqs: rCsnk2a1 [omission]
    *** source: 9685505-Fig-1b
  *** rCsnk2b boundby[WB] rAtf1(214-271)[GST] is detectable
    *** cells: none
    *** inhibited by: rAtf1(WT) [substitution]
    *** enhanced by: rCsnk2a1 [addition]
    *** source: 9685505-Fig-1b
  *** rCsnk2b boundby[WB] rAtf1[GST] is undetectable
    *** cells: none
    *** source: 9685505-Fig-1a
  *** rCsnk2b[Ab] boundby[FarWestern] rCsnk2a1[35S] is detectable
    *** cells: none
    *** source: 9685505-Fig-2b
  *** Csrp2-gene promo-reporter[Luc] is increased itpo xAtf2
    *** cells: mrVSMCs in BMS
    *** enhanced by: Tgfb1 (24 hr) [stim]
    *** source: 18387947-Fig-8a
  *** Csrp2-gene promo-reporter[Luc] is unchanged itpo xCreb1
    *** cells: mrVSMCs in BMS
    *** source: 18387947-Fig-8a
  *** Ctgf-gene mRNA[RTPCR] is increased itao Smad2 [KO]
    *** cells: mEFs in BMS
    *** source: 20595680-Fig-9d
  *** Ctgf-gene mRNA[RTPCR] is unchanged itao Smad2 [RNAi]
    *** cells: mTECs in BMS
    *** source: 20595680-Fig-9c
  *** Ctnna1[Ab] copptby[WB] Cdh1[Ab] is detectable
    *** cells: NBTII in BMS
    *** unaffected by: Pervanadate [addition]
    *** unaffected by: Egf (30 min) [stim]
    *** unaffected by: Fgf1 + Heparin (30 min) [stim]
    *** unaffected by: Orthovanadate [addition]
    *** source: 10187801-Fig-2
  *** Ctnna1[Ab] copptby[WB] Ctnnb1[Ab] is decreased itpo xFer
    *** cells: RWP1 in BMS
    *** source: 12640114-Fig-2a
  *** Ctnna1[Ab] copptby[WB] Ctnnb1[Ab] is decreased itpo xFyn
    *** cells: RWP1 in BMS
    *** source: 12640114-Fig-2b
  *** Ctnna1[Ab] copptby[WB] Ctnnb1[Ab] is decreased itpo xKras(G12V)"CA"
    *** cells: IEC18 in BMS
    *** reversed by: Genistein [addition]
    *** source: 12640114-Fig-3c
  *** Ctnna1[Ab] copptby[WB] Ctnnb1[Ab] is detectable
    *** cells: IEC18 in BMS
    *** inhibited by: xKras(G12V)"CA" [addition]
    *** source: 12640114-Fig-3c
  *** Ctnna1[Ab] copptby[WB] Ctnnb1[Ab] is detectable
    *** cells: RWP1 in BMS
    *** inhibited by: xFer [addition]
    *** inhibited by: xFyn [addition]
    *** source: 12640114-Fig-2a,2b
  *** Ctnna1[Ab] copptby[WB] xCtnnb1[tAb] is detectable
    *** cells: IEC18<xKras(G12V)"CA"> in BMS
    *** inhibited by: xCtnnb1(Y142F) [substitution]
    *** source: 12640114-Fig-4b
  *** Ctnna1[Ab] snaggedby[WB] rCtnnb1[GST] is detectable
    *** cells: RWP1 in BMS
    *** inhibited by: rCtnnb1(Y142E) [substitution]
    *** source: 12640114-Fig-1c
*** Ctnnb1--
  *** Ctnnb1-gene mRNA[Northern] is detectable
    *** cells: HELA in BMS
    *** unaffected by: Pin1 [AntiSense]
    *** source: 11533658-Fig-3b
  *** Ctnnb1-gene mRNA[Northern] is unchanged itpo xPin1
    *** cells: HELA in BMS
    *** source: 11533658-Fig-3b
  *** Ctnnb1-gene mRNA[RTPCR] is detectable
    *** cells: HEK293<xCtnnb1> in BMS
    *** unaffected by: xCtnnb1(S33Y) [substitution]
    *** unaffected by: xCtnnb1(K19R/K49R) [substitution]
    *** unaffected by: xCtnnb1(K19R) [substitution]
    *** unaffected by: xCtnnb1(K49R) [substitution]
    *** source: 16849322-Fig-5b
  *** xCtnnb1(S33Y)[Ab] snaggedby[WB] rCdh1(mnr)"CT"[GST] is detectable
    *** cells: HEK293<xCtnnb1(S33Y)> in BMS
    *** inhibited by: xCtnnb1 [substitution]
    *** source: 16849322-Fig-4a
  *** xCtnnb1(S33Y)[Ab] snaggedby[WB] rCdh1(mnr)"CT"[GST] is detectable
    *** cells: HEK293<xCtnnb1(S33Y)> in BMS
    *** inhibited by: xCtnnb1 [substitution]
    *** unaffected by: xCtnnb1(K19R/K49R) [substitution]
    *** unaffected by: xCtnnb1(K19R) [substitution]
    *** inhibited by: xCtnnb1(K49R) [substitution]
    *** source: 16849322-Fig-4b
  *** xCtnnb1(S33Y)[tAb]IP phos(S45)[phosAb] is increased itpo xAxin1
    *** cells: Xembryos<xCtnnb1(S33Y)> in BMS
    *** unaffected by: xAxin1(357-526)"delGsk3-binding" [substitution]
    *** inhibited by: xAxin1(526-722)"delCtnnb1-binding" [substitution]
    *** unaffected by: xAxin1(903-922)"delDix" [substitution]
    *** inhibited by: xAxin1(619-903)"delS45K" [substitution]
    *** source: 11955436-Fig-3b
  *** rCtnnb1[32P] phos[32P-ATP] is unchanged by xTnik[Ab]IP
    *** cells: none
    *** IPfrom: HEK293T<xTnik> in BMS
    *** unaffected by: xTnik(R152A/D153A) [substitution]
    *** unaffected by: xTnik(K54A) [substitution]
    *** unaffected by: xTnik(D171A/F172A) [substitution]
    *** source: 19816403-Fig-4d
  *** rCtnnb1[Ab] boundby[WB] rPtk6[GST] is detectable
    *** cells: none
    *** comment: enhanced by prephos of rCtnnb1 with rPtk6
    *** source: 20016641-Fig-3b
  *** rCtnnb1[Ab] boundby[WB] rPtk6[GST] is detectable
    *** cells: none
    *** partially inhibited by: rPtk6(mnr)"SH2SH3" [substitution]
    *** partially inhibited by: rPtk6(mnr)"SH2" [substitution]
    *** inhibited by: rPtk6(mnr)"SH3" [substitution]
    *** source: 20016641-Fig-3b
  *** Ctnnb1[Ab] boundto(Myc-gene)[ChIP] is detectable
    *** cells: HCT116 in BMS "treated with Anisomycin"
    *** source: 16007074-Fig-2d
  *** Ctnnb1[Ab] colocwith[IHC] Ptprf[Ab] is detectable
    *** cells: NBTII in BMS
    *** source: 10187801-Fig-4
  *** Ctnnb1[Ab] copptby[WB] Apc[Ab] is decreased itpo xPin1
    *** cells: HELA in BMS
    *** source: 11533658-Fig-6b
  *** Ctnnb1[Ab] copptby[WB] Apc[Ab] is detectable
    *** cells: HCT116 in BMS
    *** source: 15331612-Fig-4b
  *** Ctnnb1[Ab] copptby[WB] Apc[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 15331612-Fig-4b
  *** Ctnnb1[Ab] copptby[WB] Apc[Ab] is detectable
    *** cells: HT29 in BMS
    *** source: 15331612-Fig-4b
  *** Ctnnb1[Ab] copptby[WB] Axin1[Ab] is detectable
    *** cells: LS174T in BMS
    *** source: 20128690-Fig-1c
  *** Ctnnb1[Ab] copptby[WB] Ppp2r2a[Ab] is detectable
    *** cells: SW480 in BMS
    *** source: 19556239-Fig-4a
  *** Ctnnb1[Ab] copptby[WB] Tcf7l2[Ab] is decreased itpo xApc
    *** cells: HCT116 in BMS
    *** enhanced by: xTfap2a [addition]
    *** source: 15331612-Fig-5
  *** Ctnnb1[Ab] copptby[WB] Tcf7l2[Ab] is decreased itpo xApc
    *** cells: HEK293 in BMS
    *** enhanced by: xTfap2a [addition]
    *** source: 15331612-Fig-5
  *** Ctnnb1[Ab] copptby[WB] Tcf7l2[Ab] is decreased itpo xApc
    *** cells: HT29 in BMS
    *** enhanced by: xTfap2a [addition]
    *** source: 15331612-Fig-5
  *** Ctnnb1[Ab] copptby[WB] Tcf7l2[Ab] is decreased itpo xTfap2a
    *** cells: HCT116 in BMS
    *** enhanced by: xApc [addition]
    *** source: 15331612-Fig-5
  *** Ctnnb1[Ab] copptby[WB] Tcf7l2[Ab] is decreased itpo xTfap2a
    *** cells: HEK293 in BMS
    *** enhanced by: xApc [addition]
    *** source: 15331612-Fig-5
  *** Ctnnb1[Ab] copptby[WB] Tcf7l2[Ab] is decreased itpo xTfap2a
    *** cells: HT29 in BMS
    *** enhanced by: xApc [addition]
    *** source: 15331612-Fig-5
  *** Ctnnb1[Ab] copptby[WB] Tfap2a[Ab] is detectable
    *** cells: HCT116 in BMS
    *** source: 15331612-Fig-4b
  *** Ctnnb1[Ab] copptby[WB] Tfap2a[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 15331612-Fig-4b
  *** Ctnnb1[Ab] copptby[WB] Tfap2a[Ab] is detectable
    *** cells: HT29 in BMS
    *** source: 15331612-Fig-4b
  *** Ctnnb1[Ab] copptby[WB] Tnik[Ab] is detectable
    *** cells: DLD1 in BMS
    *** source: 20530691-Fig-1a
  *** Ctnnb1[Ab] copptby[WB] Tnik[Ab] is detectable
    *** cells: HCT116 in BMS
    *** source: 20530691-Fig-1a
  *** xCtnnb1[Ab] infraction(cyto-nuc)[WB] is detectable
    *** cells: HEK293<xCtnnb1> in BMS
    *** unaffected by: xPtk6 [addition]
    *** unaffected by: xPtk6(Y447F)"CA" [addition]
    *** unaffected by: xPtk6(K219M)"KD" [addition]
    *** source: 20016641-Fig-2a
  *** Ctnnb1[Ab] infraction(cytosolic)[WB] is increased itpo xFzd9
    *** cells: HEK293T in BMS
    *** enhanced by: xWnt2 [addition]
    *** source: 12138115-Fig-2c
  *** Ctnnb1[Ab] infraction(cytosolic)[WB] is increased itpo xFzd9
    *** cells: HEK293T in BMS
    *** source: 12138115-Fig-1c
  *** Ctnnb1[Ab] infraction(cytosolic)[WB] is increased itpo xFzd9
    *** cells: HEK293T in BMS
    *** unaffected by: xFzd9(1-587)"C5" [substitution]
    *** partially inhibited by: xFzd9(1-577)"C15" [substitution]
    *** partially inhibited by: xFzd9(1-566)"C26" [substitution]
    *** partially inhibited by: xFzd9(1-554)"C38" [substitution]
    *** source: 12138115-Fig-5a
  *** Ctnnb1[Ab] infraction(cytosolic)[WB] is increased itpo xFzd9
    *** cells: HEK293T in BMS
    *** unaffected by: xFzd9(del(58-174))"N" [substitution]
    *** source: 12138115-Fig-6b
  *** xCtnnb1[Ab] infraction(cytosolic)[WB] is increased itpo xYwhaz
    *** cells: CHO<xCtnnb1> in BMS
    *** source: 15492215-Fig-2e
  *** Ctnnb1[Ab] infraction(membrane)[WB] is unchanged itpo xFzd9
    *** cells: HEK293T in BMS
    *** source: 12138115-Fig-1c
  *** Ctnnb1[Ab] infraction(nuclear)[WB] is unchanged itpo xTfap2a
    *** cells: HCT116 in BMS
    *** source: 15331612-Fig-3
  *** Ctnnb1[Ab] infraction(nuclear)[WB] is unchanged itpo xTfap2a
    *** cells: HEK293 in BMS
    *** source: 15331612-Fig-3
  *** Ctnnb1[Ab] infraction(nuclear)[WB] is unchanged itpo xTfap2a
    *** cells: HT29 in BMS
    *** source: 15331612-Fig-3
  *** xCtnnb1[Ab] infraction(nuclear)[WB] is unchanged itpo xYwhaz
    *** cells: CHO<xCtnnb1> in BMS
    *** source: 15492215-Fig-2e
  *** xCtnnb1[Ab] infraction(P100)[WB] is detectable
    *** cells: SKBR3 in BMS
    *** partially inhibited by: xCtnnb1(S37A) [substitution]
    *** source: 9312064-Fig-4b
  *** xCtnnb1[Ab] infraction(S100)[WB] is detectable
    *** cells: SKBR3 in BMS
    *** enhanced by: xCtnnb1(S37A) [substitution]
    *** source: 9312064-Fig-4b
  *** xCtnnb1[Ab] infraction(S100)[WB] is detectable
    *** cells: SKBR3 in BMS "treated with ALLN and Clasto-Lactacystin for 18 hr"
    *** enhanced by: xCtnnb1(S37A) [substitution]
    *** source: 9312064-Fig-4c
  *** Ctnnb1[Ab] oligo-binding[EMSA] is decreased itpo xApc
    *** cells: HT29<Apc~null> in BMS
    *** oligo: oligo-name-not-reported sequence-not-reported
    *** source: 9065401-Fig-4
  *** xCtnnb1[Ab] oligo-binding[EMSA] is decreased itpo xNlk
    *** cells: HEK293<xCtnnb1><xTcf7l2> in BMS
    *** inhibited by: xNlk(K155M) [substitution]
    *** source: 10391247-Fig-5b
  *** xCtnnb1[Ab] oligo-binding[EMSA] is detectable
    *** cells: HEK293<xCtnnb1><xTcf7l2> in BMS "nuclear-extracts"
    *** inhibited by: xNlk [addition]
    *** unaffected by: xNlk(K155M) [addition]
    *** source: 12556497-Fig-7b
  *** xCtnnb1[Ab] oligo-binding[EMSA] is detectable
    *** cells: HEK293<xCtnnb1><xTcf7l2> in BMS "nuclear-extracts"
    *** unaffected by: xTcf7l2(T178V/T189V) [substitution]
    *** source: 12556497-Fig-7b
  *** Ctnnb1[Ab] prot-exp[WB] is detectable
    *** cells: HELA in BMS
    *** partially reqs: Pin1 [AntiSense]
    *** source: 11533658-Fig-3a
  *** Ctnnb1[Ab] prot-exp[WB] is detectable-but unchanged itpo xBraf
    *** cells: MCF10A in BMLS
    *** inhibited by: xBraf(V600E) [substitution]
    *** unaffected by: xBraf(R188L) [substitution]
    *** inhibited by: xBraf(V600E/R118L) [substitution]
    *** unaffected by: xBraf(S446A/S5447A) [substitution]
    *** inhibited by: xBraf(V600E/S446A/S5447A) [substitution]
    *** unaffected by: xBraf(S365A/S446A/S447A/D448A/D449A) [substitution]
    *** inhibited by: xBraf(V600E/S365A/S446A/S447A/D448A/D449A) [substitution]
    *** unaffected by: xBraf(S365A) [substitution]
    *** source: 16702958-Fig-8a
  *** Ctnnb1[Ab] prot-exp[WB] is detectable-but unchanged itpo xBraf
    *** cells: MCF10A in BMLS
    *** inhibited by: xBraf(V600E) [substitution]
    *** unaffected by: xBraf(S729A) [substitution]
    *** inhibited by: xBraf(V600E/S729A) [substitution]
    *** source: 16702958-Fig-8b
  *** Ctnnb1[Ab] prot-exp[WB] is increased itpo xPin1
    *** cells: HELA in BMS
    *** source: 11533658-Fig-3a
  *** xCtnnb1[Ab] prot-exp[WB] is increased itpo xYwhaz
    *** cells: CHO<xCtnnb1> in BMS
    *** source: 15492215-Fig-2d
  *** Ctnnb1[Ab] prot-stability[35S-pulse-chase] is increased itpo xPin1
    *** cells: HELA in BMS
    *** source: 11533658-Fig-3c
  *** Ctnnb1[Ab] snaggedby[WB] rPik3r1[GST] is detectable
    *** cells: HN5 in BMS
    *** source: 11716761-Fig-6b
  *** Ctnnb1[Ab] snaggedby[WB] rPik3r1[GST] is detectable
    *** cells: hSVKs in BMS "containing hydrocortisone"
    *** source: 11716761-Fig-6b
  *** Ctnnb1[Ab] snaggedby[WB] rPik3r1[GST] is detectable
    *** cells: MDCK in BMS
    *** source: 11716761-Fig-6b
  *** Ctnnb1[Ab] snaggedby[WB] rPik3r1[GST] is detectable
    *** cells: SCC12F in BMS "containing hydrocortisone"
    *** source: 11716761-Fig-6b
  *** Ctnnb1[Ab]IP acetyl[KAcAb] is increased itao Hdac6 [RNAi]
    *** cells: HCT116 in BMLS
    *** source: 18356165-Fig-2b
  *** Ctnnb1[Ab]IP ubiq[UbAb] is detectable
    *** cells: HEK293T<xBtrc> in BMS "treated with ALLN for 8 hr"
    *** inhibited by: xBtrc(del(140-194))"delFbox" [substitution]
    *** source: 10228155-Fig-4b
  *** Ctnnb1[Ab]IP Yphos[pYAb] is increased itpo xFyn
    *** cells: RWP1 in BMS
    *** source: 12640114-Fig-2a
  *** Ctnnb1[Ab]IP Yphos[pYAb] is increased itpo xKras(G12V)"CA"
    *** cells: IEC18 in BMS
    *** inhibited by: Genistein [addition]
    *** source: 12640114-Fig-3c
  *** Ctnnb1[AcAb] acetyl(K49)[AcAb] is decreased itpo xHdac6
    *** cells: SW480 in BMLS
    *** source: 18356165-Fig-2h
  *** Ctnnb1[AcAb] acetyl(K49)[AcAb] is increased itpo xCbp
    *** cells: HCT116 in BMLS
    *** inhibited by: xHdac6 [addition]
    *** unaffected by: xHdac6(mnr)"CIA" [addition]
    *** source: 18356165-Fig-2e
  *** xCtnnb1[phosAb] phos(S33)[phosAb] is decreased itpo xDvl1
    *** cells: HEK293T<xCtnnb1> in BMS "treated with MG132"
    *** source: 12000790-Fig-6b
  *** Ctnnb1[phosAb] phos(S33)[phosAb] is detectable
    *** cells: HELA in BMS "treated with MG132"
    *** partially inhibited by: CKI7 [addition]
    *** unaffected by: H89 [addition]
    *** source: 12000790-Fig-5d
  *** Ctnnb1[phosAb] phos(S33/S37/T41)[phosAb] is increased itao Ppp1cc [RNAi]
    *** cells: SW480 in BMS
    *** source: 19556239-Fig-1c
  *** Ctnnb1[phosAb] phos(S33/S37/T41)[phosAb] is increased itao Ppp2ca [RNAi]
    *** cells: SW480 in BMS
    *** source: 19556239-Fig-1c
  *** Ctnnb1[phosAb] phos(S33/S37/T41)[phosAb] is increased itao Ppp2r2a [RNAi]
    *** cells: SW480 in BMS
    *** source: 19556239-Fig-3c
  *** Ctnnb1[phosAb] phos(S33/S37/T41)[phosAb] is increased itao Ppp5c [RNAi]
    *** cells: SW480 in BMS
    *** source: 19556239-Fig-1c
  *** rCtnnb1[phosAb] phos(S45)[phosAb] is decreased by xPpp2r2a[tAb]IP
    *** cells: none
    *** IPfrom: HEK293T<xPpp2r2a><xPpp2ca> in BMS
    *** comment: IP contains both xPpp2r2a and xPpp2ca
    *** source: 19556239-Fig-5f
  *** Ctnnb1[phosAb] phos(S45)[phosAb] is detectable
    *** cells: SW480 in BMS
    *** unaffected by: Ppp2r5a [RNAi]
    *** source: 19556239-Fig-3a
  *** Ctnnb1[phosAb] phos(S45)[phosAb] is detectable
    *** cells: SW480 in BMS
    *** unaffected by: Ppp2r5b [RNAi]
    *** source: 19556239-Fig-3a
  *** Ctnnb1[phosAb] phos(S45)[phosAb] is detectable
    *** cells: SW480 in BMS
    *** unaffected by: Ppp2r5d [RNAi]
    *** source: 19556239-Fig-3a
  *** Ctnnb1[phosAb] phos(S45)[phosAb] is increased itao Ppp1cc [RNAi]
    *** cells: SW480 in BMS
    *** source: 19556239-Fig-1c
  *** Ctnnb1[phosAb] phos(S45)[phosAb] is increased itao Ppp2ca [RNAi]
    *** cells: SW480 in BMS
    *** source: 19556239-Fig-1c
  *** Ctnnb1[phosAb] phos(S45)[phosAb] is increased itao Ppp2ca [RNAi]
    *** cells: SW480 in BMS
    *** source: 19556239-Fig-3a
  *** Ctnnb1[phosAb] phos(S45)[phosAb] is increased itao Ppp2r2a [RNAi]
    *** cells: SW480 in BMS
    *** source: 19556239-Fig-3a
  *** Ctnnb1[phosAb] phos(S45)[phosAb] is increased itao Ppp2r2a [RNAi]
    *** cells: SW480 in BMS
    *** source: 19556239-Fig-3c
  *** Ctnnb1[phosAb] phos(S45)[phosAb] is increased itao Ppp5c [RNAi]
    *** cells: SW480 in BMS
    *** source: 19556239-Fig-1c
  *** Ctnnb1[phosAb] phos(S552)[phosAb] is increased itao Ppp2r2a [RNAi]
    *** cells: SW480 in BMS
    *** source: 19556239-Fig-3c
  *** Ctnnb1[phosAb] phos(S675)[phosAb] is increased itao Ppp2r2a [RNAi]
    *** cells: SW480 in BMS
    *** source: 19556239-Fig-3c
  *** xCtnnb1[phosAb] phos(T41/S45)[phosAb] is decreased itpo xDvl1
    *** cells: HEK293T<xCtnnb1> in BMS "treated with MG132"
    *** source: 12000790-Fig-6b
  *** Ctnnb1[phosAb]IP phos(S33/S37/T41)[phosAb] is decreased by rPP2a
    *** cells: none
    *** IPfrom: HCT116 in BMS
    *** comment: Ctnnb1 was IPed using Abs to S33/S37/T41, S45, S552, S675
    *** source: 19556239-Fig-1d
  *** Ctnnb1[phosAb]IP phos(S33/S37/T41)[phosAb] is unchanged by rPpp1cc
    *** cells: none
    *** IPfrom: HCT116 in BMS
    *** comment: Ctnnb1 was IPed using Abs to S33/S37/T41, S45, S552, S675
    *** source: 19556239-Fig-1d
  *** Ctnnb1[phosAb]IP phos(S33/S37/T41)[phosAb] is unchanged by rPpp5c
    *** cells: none
    *** IPfrom: HCT116 in BMS
    *** comment: Ctnnb1 was IPed using Abs to S33/S37/T41, S45, S552, S675
    *** source: 19556239-Fig-1d
  *** rCtnnb1[pYAb] Yphos[pYAb] is increased by rFyn
    *** cells: none
    *** inhibited by: rCtnnb1(Y142F) [substitution]
    *** source: 12640114-Fig-1b
  *** Ctnnb1[tAb] copptby[WB] xGsk3b[tAb] is detectable
    *** cells: COS<xAxin2><xGsk3b> in BMS
    *** reqs: xAxin2 [omission]
    *** source: 9566905-Fig-6a
  *** xCtnnb1[tAb] copptby[WB] xLef1[tAb] is detectable
    *** cells: HEK293<xCtnnb1><xNlk><xLef1> in BMS
    *** unaffected by: xLef1(T155A/S166A) [substitution]
    *** source: 12556497-Fig-5b
  *** xCtnnb1[tAb] copptby[WB] xNlk[tAb] is detectable
    *** cells: HEK293<xCtnnb1><xNlk><xLef1> in BMS
    *** reqs: xLef1 [omission]
    *** source: 12556497-Fig-1
  *** xCtnnb1[tAb] copptby[WB] xNlk[tAb] is detectable
    *** cells: HEK293<xCtnnb1><xNlk><xLef1> in BMS
    *** reqs: xTcf7l2 [omission]
    *** source: 12556497-Fig-2
  *** xCtnnb1[tAb] copptby[WB] xPpp2r2a[Ab] is detectable
    *** cells: HEK293T<xCtnnb1><xPpp2r2a> in BMS
    *** enhanced by: xPpp2r2a(mnr)"del1" [substitution]
    *** unaffected by: xPpp2r2a(mnr)"del2" [substitution]
    *** unaffected by: xPpp2r2a(mnr)"del3" [substitution]
    *** source: 19556239-Fig-4f
  *** xCtnnb1[tAb] copptby[WB] xPpp2r2a[Ab] is detectable
    *** cells: HEK293T<xCtnnb1><xPpp2r2a> in BMS
    *** unaffected by: xCtnnb1(mnr)"delC" [substitution]
    *** unaffected by: xCtnnb1(mnr)"Cterm" [substitution]
    *** inhibited by: xCtnnb1(mnr)"Nterm" [substitution]
    *** source: 19556239-Fig-4d
  *** xCtnnb1[tAb] copptby[WB] xTcf7l2[tAb] is detectable
    *** cells: HEK293<xCtnnb1><xTcf7l2><xLef1> in BMS
    *** unaffected by: xTcf7l2(T178V/T189V) [substitution]
    *** source: 12556497-Fig-5b
  *** xCtnnb1[tAb] copptby[WB] xYwhaz[tAb] is detectable
    *** cells: HEK293T<xYwhaz><xCtnnb1> in BMS
    *** source: 15492215-Fig-1b
  *** xCtnnb1[tAb] infraction(cytoplasmic)[WB] is detectable
    *** cells: HEK293<xCtnnb1> in BMS
    *** enhanced by: xCtnnb1(S33Y) [substitution]
    *** enhanced by: xCtnnb1(K19R/K49R) [substitution]
    *** enhanced by: xCtnnb1(K19R) [substitution]
    *** unaffected by: xCtnnb1(K49R) [substitution]
    *** source: 16849322-Fig-5a
  *** xCtnnb1[tAb] infraction(nuclear)[WB] is detectable
    *** cells: HEK293<xCtnnb1> in BMS
    *** enhanced by: xCtnnb1(S33Y) [substitution]
    *** enhanced by: xCtnnb1(K19R/K49R) [substitution]
    *** enhanced by: xCtnnb1(K19R) [substitution]
    *** unaffected by: xCtnnb1(K49R) [substitution]
    *** source: 16849322-Fig-5a
  *** xCtnnb1[tAb] prot-exp[WB] is detectable
    *** cells: HEK293<xCtnnb1> in BMS
    *** enhanced by: xCtnnb1(S33Y) [substitution]
    *** enhanced by: xCtnnb1(K19R/K49R) [substitution]
    *** enhanced by: xCtnnb1(K19R) [substitution]
    *** inhibited by: xCtnnb1(K49R) [substitution]
    *** source: 16849322-Fig-5a
  *** xCtnnb1[tAb]IP acetyl(K49)[AcAb] is decreased itpo xHdac6
    *** cells: HEK293T in BMS
    *** source: 18356165-Fig-2g
  *** xCtnnb1[tAb]IP acetyl(K49)[AcAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xCtnnb1(K49R) [substitution]
    *** source: 18356165-Fig-2d
  *** xCtnnb1[tAb]IP phos(S33/S37/S41)[phosAb] is detectable
    *** cells: HEK293<xCtnnb1> in BMS
    *** inhibited by: xCtnnb1(S33Y) [substitution]
    *** unaffected by: xCtnnb1(K19R/K49R) [substitution]
    *** unaffected by: xCtnnb1(K19R) [substitution]
    *** unaffected by: xCtnnb1(K49R) [substitution]
    *** source: 16849322-Fig-6
  *** xCtnnb1[tAb]IP phos(S45)[phosAb] is decreased itpo xHdac6
    *** cells: HEK293T in BMS
    *** source: 18356165-Fig-2g
  *** xCtnnb1[tAb]IP phos(S45)[phosAb] is detectable-but unchanged by pCsnk2
    *** cells: none
    *** IPfrom: HEK293T<xCtnnb1> in BMS
    *** source: 12051714-Fig-2
  *** xCtnnb1[tAb]IP phos(S45)[phosAb] is increased itpo xAxin1
    *** cells: Xembryos<xCtnnb1> in BMS
    *** unaffected by: xAxin1(mnr)"delRGS" [substitution]
    *** source: 11955436-Fig-3b
  *** xCtnnb1[tAb]IP ubiq[tUbAb] is detectable
    *** cells: HEK293<xCtnnb1><xUbiq> in BMS
    *** inhibited by: xBtrc(mnr)"DN" [addition]
    *** source: 16849322-Fig-7b
  *** xCtnnb1[tAb]IP ubiq[tUbAb] is detectable
    *** cells: HEK293<xCtnnb1><xUbiq> in BMS
    *** inhibited by: xCtnnb1(S33Y) [substitution]
    *** unaffected by: xCtnnb1(K19R/K49R) [substitution]
    *** unaffected by: xCtnnb1(K19R) [substitution]
    *** unaffected by: xCtnnb1(K49R) [substitution]
    *** source: 16849322-Fig-7a
  *** xCtnnb1[tAb]IP upshift[WBMS] is unchanged by xCyld[tAb]IP
    *** cells: none
    *** comment: IPs were from separate transfection of HEK293T
    *** comment: xCtnnb1 was expressed in the presence of MG132
    *** source: 12917691-Fig-3e
  *** xCtnnb1[XFP] locatedin(nucleus)[IHC] is increased itpo xPin1
    *** cells: HELA<xCtnnb1> in BMS
    *** inhibited by: xCtnnb1(S246A) [substitution]
    *** source: 11533658-Fig-7f
  *** rCtnnb1{phos}[phosAb] phos(S33/S37/T41)[phosAb] is decreased by xPpp2r2a[tAb]IP
    *** cells: none
    *** IPfrom: HEK293T<xPpp2r2a><xPpp2ca> in BMS
    *** comment: IP contains both xPpp2r2a and xPpp2ca
    *** comment: rCttnb1 was phosed with Csnk1 and Gsk3b
    *** source: 19556239-Fig-5f
*** Ctnnd1--
  *** Ctnnd1[Ab] copptby[WB] Cdh1[Ab] is detectable
    *** cells: A431 in BMLS
    *** unaffected by: Egf (5 min) [stim]
    *** source: 14996911-Fig-2c
  *** Ctnnd1[Ab] copptby[WB] Fak1[Ab] is undetectable
    *** cells: A431 in BMS
    *** unaffected by: Egf (5 min) [stim]
    *** source: 7623846-Fig-2
  *** Ctnnd1[Ab] copptby[WB] Fer[Ab] is detectable
    *** cells: A431 in BMS
    *** unaffected by: Egf (5 min) [stim]
    *** source: 7623846-Fig-2
  *** Ctnnd1[Ab] copptby[WB] Fer[Ab] is detectable
    *** cells: NIH3T3 in BMS
    *** unaffected by: Egf (5 min) [stim]
    *** source: 7623846-Fig-3b
  *** Ctnnd1[Ab] copptby[WB] Fer[Ab] is detectable
    *** cells: NIH3T3<xEgfR> in BMS
    *** unaffected by: Egf (5 min) [stim]
    *** source: 7623846-Fig-3b
  *** Ctnnd1[Ab] copptby[WB] Fer[Ab] is detectable
    *** cells: SWISS3T3 in BMS
    *** unaffected by: Pdgf (5 min) [stim]
    *** source: 7623846-Fig-3d
  *** Ctnnd1[Ab] copptby[WB] Fyn[Ab] is detectable
    *** cells: IEC18 in BMS
    *** unaffected by: xKras(G12V)"CA" [addition]
    *** source: 12640114-Fig-6b
  *** Ctnnd1[Ab] copptby[WB] Yes1[Ab] is detectable
    *** cells: IEC18 in BMS
    *** enhanced by: xKras(G12V)"CA" [addition]
    *** source: 12640114-Fig-7a
  *** xCtnnd1[Ab]IP phos(Y228)[phosAb] is increased itpo xSrc(P527F)"CA"
    *** cells: COS7 in BMS
    *** inhibited by: xCtnnd1(Y228F) [substitution]
    *** source: 14996911-Fig-1d
  *** Ctnnd1[Ab]IP Yphos[pYAb] is increased itpo xKras(G12V)"CA"
    *** cells: IEC18 in BMS
    *** source: 12640114-Fig-6a
  *** Ctnnd1[phosAb] phos(Y228)[phosAb] is detectable
    *** cells: A431 in BMS
    *** unaffected by: AG1478 [addition]
    *** unaffected by: EKI [addition]
    *** partially inhibited by: PP1 [addition]
    *** partially inhibited by: SU6656 [addition]
    *** source: 14996911-Fig-6a
  *** Ctnnd1[phosAb] phos(Y228)[phosAb] is increased itpo xSrc(P527F)"CA"
    *** cells: NIH3T3 in BMS
    *** source: 14996911-Fig-1a
  *** Ctsd[Ab]IP cleavage[WB] is detectable
    *** cells: MCF7<Becn1~null><xBecn1> in BMS
    *** does not req: xBecn1 [omission]
    *** source: 16874027(D)
  *** Cttn[Ab]IP Yphos[pYAb] is increased itpo xRala(Q72L)"CA"
    *** cells: HEK293 in BMLS
    *** source: 10675331-Fig-5a
  *** Cul1[Ab] copptby[WB] xFbxo11[tAb] is detectable
    *** cells: HEK293<xFbxo11> in BMS "nuclear extracts"
    *** inhibited by: xFbxo11(del(152-197)) [substitution]
    *** source: 17098746-Fig-2b
  *** xCul1[tAb] copptby[WB] xRbx1[tAb] is detectable
    *** cells: COS7 in BMS
    *** unaffected by: xBtrc [addition]
    *** source: 11359933-Fig-2f
  *** CxcL1-gene mRNA[RTPCR] is detectable
    *** cells: mEFs in BMS
    *** reqs: Egr1 [KO]
    *** source: 15958557-Fig-1
  *** CxcL1-gene mRNA[RTPCR] is increased itao Traf2 [KO]
    *** cells: mEFs in BMS
    *** source: 18997792-Fig-S1d
  *** CxcL1-gene mRNA[RTPCR] is increased itao Traf3 [KO]
    *** cells: mEFs in BMS
    *** source: 18997792-Fig-S1d
  *** CxcL10-gene mRNA[RTPCR] is increased itao Traf2 [KO]
    *** cells: mEFs in BMS
    *** source: 18997792-Fig-S1d
  *** CxcL10-gene mRNA[RTPCR] is increased itao Traf3 [KO]
    *** cells: mEFs in BMS
    *** source: 18997792-Fig-S1d
  *** CxcR4-gene mRNA[RTPCR] is detectable
    *** cells: mSpBCs in BMS "treated with anti-Cd40 (24 hr)"
    *** partially inhibited by: kMekk1(1-1188)"del-kinase-domain" [addition]
    *** source: 17143273-Fig-6c
  *** rCyclinA?[35S] boundby[WB] rRb1[Ab] is undetectable
    *** cells: none
    *** source: 8490963-Fig-1a
  *** rCyclinA1(78-240)[35S] boundby[WB] rRb1[GST] is detectable
    *** cells: none
    *** inhibited by: rCyclinA1(1-77) [substitution]
    *** partially inhibited by: rCyclinA1(1-220) [substitution]
    *** inhibited by: rCyclinA1(242-465) [substitution]
    *** source: 10022926-Fig-3d
  *** rCyclinA1[35S] boundby[WB] rCdkn1a[GST] is detectable
    *** cells: none
    *** source: 10022926-Fig-4
  *** rCyclinA1[35S] boundby[WB] rE2f1[GST] is detectable
    *** cells: none
    *** unaffected by: rE2f1(1-150) [substitution]
    *** inhibited by: rE2f1(1-76) [substitution]
    *** inhibited by: rE2f1(283-437) [substitution]
    *** source: 10022926-Fig-2a
  *** rCyclinA1[35S] boundby[WB] rRb1(373-928)[GST] is detectable
    *** cells: none
    *** inhibited by: rRb1(373-590) [substitution]
    *** unaffected by: rRb1(623-928) [substitution]
    *** unaffected by: rRb1(773-928) [substitution]
    *** inhibited by: rRb1(838-928) [substitution]
    *** source: 10022926-Fig-3b
  *** rCyclinA1[35S] boundby[WB] rRb1[GST] is detectable
    *** cells: none
    *** source: 10022926-Fig-3a
  *** rCyclinA1[35S] boundby[WB] rRbl1(649-816)[GST] is detectable
    *** cells: none
    *** inhibited by: rRbl1(242-451) [substitution]
    *** inhibited by: rRbl1(452-648) [substitution]
    *** source: 10022926-Fig-3c
  *** rCyclinA1[35S] boundby[WB] rRbl1[GST] is detectable
    *** cells: none
    *** source: 10022926-Fig-3a
  *** rCyclinA1[35S] boundby[WB] rRbl2[GST] is detectable
    *** cells: none
    *** source: 10022926-Fig-3a
  *** CyclinA1[Ab] prot-exp[WB] is increased irt Serum (times)
    *** cells: MG63 in BMLS
    *** times: 0 4+ 8+ 12++ 16++ 20++ 24++ 28+ 32 hr
    *** comment: max Sphase occurred at 24 hr
    *** comment: max G2Mphase occurred at 28 hr
    *** source: 10022926-Fig-1c
  *** xCyclinA1[Ab] snaggedby[WB] xE2f1[GST] is detectable
    *** cells: SF9<xCyclinA1><xCdk2> in BMS
    *** source: 10022926-Fig-2b
  *** rCyclinB1[35S] boundby[WB] rRb1[Ab] is undetectable
    *** cells: none
    *** source: 8490963-Fig-1a
  *** rCyclinB2[35S] boundby[WB] rRb1[Ab] is undetectable
    *** cells: none
    *** source: 8490963-Fig-1a
  *** rCyclinC[35S] boundby[WB] rRb1[Ab] is undetectable
    *** cells: none
    *** source: 8490963-Fig-1b
  *** CyclinC[Ab] copptby[WB] Cdk8[Ab] is unchanged itao Med23 [KO]
    *** cells: mESCs in BMS
    *** source: 11934987-Fig-1
  *** CyclinD1-gene mRNA[Northern] is increased itpo xPin1
    *** cells: MCF7 in BMS
    *** source: 11533658-Fig-1b
  *** CyclinD1-gene mRNA[RTPCR] is increased itpo xPin1
    *** cells: HELA in BMS
    *** source: 11432833-Fig-3c
  *** CyclinD1-gene mRNA[RTPCR] is increased itpo xPin1
    *** cells: MCF7 in BMS
    *** source: 11432833-Fig-3c
  *** CyclinD1-gene mRNA[RTPCR] is unchanged itao Tnik [RNAi]
    *** cells: DLD1 in BMS
    *** source: 20530691-Fig-5
  *** CyclinD1-gene mRNA[RTPCR] is unchanged itao Tnik [RNAi]
    *** cells: HCT116 in BMS
    *** source: 20530691-Fig-5
  *** CyclinD1-gene promo-reporter[Luc] is detectable
    *** cells: MCF10A in BMS
    *** inhibited by: xTcf7l2(31-619)"DN" [addition]
    *** source: 15026412-Fig-6b
  *** CyclinD1-gene promo-reporter[Luc] is increased itpo xCtnnb1
    *** cells: HELA in BMS
    *** source: 11533658-Fig-2a
  *** CyclinD1-gene promo-reporter[Luc] is increased itpo xCtnnb1(mnr)"non-degradable"
    *** cells: HEK293<xTcf7l2(del(128-150))> in BMS
    *** enhanced by: xPias4 [addition]
    *** inhibited by: xPias4(C342A/C347A) [substitution]
    *** source: 12727872-Fig-7f
  *** CyclinD1-gene promo-reporter[Luc] is increased itpo xHras(Q61L)
    *** cells: HELA<xJun> in BMS
    *** enhanced by: xPin1 [addition]
    *** source: 11432833-Fig-5a
  *** CyclinD1-gene promo-reporter[Luc] is increased itpo xHras(Q61L)
    *** cells: MCF7<xJun> in BMS
    *** enhanced by: xPin1 [addition]
    *** source: 11432833-Fig-5c
  *** CyclinD1-gene promo-reporter[Luc] is increased itpo xJun
    *** cells: HELA<xHras(Q61L)><xPin1> in BMS
    *** source: 11432833-Fig-5a
  *** CyclinD1-gene promo-reporter[Luc] is increased itpo xJun
    *** cells: MCF7<xHras(Q61L)><xPin1> in BMS
    *** source: 11432833-Fig-5c
  *** CyclinD1-gene promo-reporter[Luc] is increased itpo xMyc
    *** cells: HELA in BMS
    *** inhibited by: xPias2 [addition]
    *** source: 9312026-Fig-5c
  *** CyclinD1-gene promo-reporter[Luc] is increased itpo xPias4
    *** cells: HEK293<xTcf7l2(del(128-150))> in BMS
    *** enhanced by: xCtnnb1(mnr)"non-degradable" [addition]
    *** source: 12727872-Fig-7f
  *** CyclinD1-gene promo-reporter[Luc] is increased itpo xPin1
    *** cells: HELA in BMS
    *** inhibited by: xPin1(W34A) [substitution]
    *** inhibited by: xPin1(K63A) [substitution]
    *** inhibited by: xPin1(R68A/R69A) [substitution]
    *** source: 11533658-Fig-2b
  *** CyclinD1-gene promo-reporter[Luc] is increased itpo xPin1
    *** cells: HELA in BMS
    *** inhibited by: xTcf7l2(mnr)"DN" [addition]
    *** source: 11533658-Fig-2c
  *** CyclinD1-gene promo-reporter[Luc] is increased itpo xPin1
    *** cells: HELA in BMS
    *** source: 11432833-Fig-3d
  *** CyclinD1-gene promo-reporter[Luc] is increased itpo xPin1
    *** cells: HELA in BMS
    *** source: 11533658-Fig-2a
  *** CyclinD1-gene promo-reporter[Luc] is increased itpo xPin1
    *** cells: HELA<xJun> in BMS
    *** enhanced by: xHras(Q61L) [addition]
    *** source: 11432833-Fig-5a
  *** CyclinD1-gene promo-reporter[Luc] is increased itpo xPin1
    *** cells: HELA<xJun> in BMS
    *** enhanced by: xJnk?(mnr)"CA" [addition]
    *** enhanced by: xHras(Q61L) [addition]
    *** source: 11432833-Fig-5e
  *** CyclinD1-gene promo-reporter[Luc] is increased itpo xPin1
    *** cells: HELA<xJun> in BMS
    *** enhanced by: xJnk?(mnr)"CA" [addition]
    *** source: 11432833-Fig-5b
  *** CyclinD1-gene promo-reporter[Luc] is increased itpo xPin1
    *** cells: HELA<xJun> in BMS
    *** inhibited by: xHras(S17N) [addition]
    *** source: 11432833-Fig-6c
  *** CyclinD1-gene promo-reporter[Luc] is increased itpo xPin1
    *** cells: HELA<xJun> in BMS
    *** inhibited by: xPin1(R68A/R69A) [substitution]
    *** source: 11432833-Fig-6a
  *** CyclinD1-gene promo-reporter[Luc] is increased itpo xPin1
    *** cells: HELA<xJun> in BMS
    *** inhibited by: xPin1(W34A) [substitution]
    *** inhibited by: xPin1(S16E) [substitution]
    *** source: 11432833-Fig-6b
  *** CyclinD1-gene promo-reporter[Luc] is increased itpo xPin1
    *** cells: HELA<xJun><xHras(Q61L)> in BMS
    *** inhibited by: xJun(S63A/S73A) [substitution]
    *** source: 11432833-Fig-6d
  *** CyclinD1-gene promo-reporter[Luc] is increased itpo xPin1
    *** cells: HELA<xJun><xJnk?(mnr)"CA"> in BMS
    *** inhibited by: xJun(S63A/S73A) [substitution]
    *** source: 11432833-Fig-6e
  *** CyclinD1-gene promo-reporter[Luc] is increased itpo xPin1
    *** cells: MCF7 in BMS
    *** source: 11432833-Fig-3d
  *** CyclinD1-gene promo-reporter[Luc] is increased itpo xPin1
    *** cells: MCF7<xJun> in BMS
    *** enhanced by: xHras(Q61L) [addition]
    *** source: 11432833-Fig-5c
  *** CyclinD1-gene promo-reporter[Luc] is increased itpo xPin1
    *** cells: MCF7<xJun> in BMS
    *** enhanced by: xJnk?(mnr)"CA" [addition]
    *** enhanced by: xHras(Q61L) [addition]
    *** source: 11432833-Fig-5e
  *** CyclinD1-gene promo-reporter[Luc] is increased itpo xPin1
    *** cells: MCF7<xJun> in BMS
    *** enhanced by: xJnk?(mnr)"CA" [addition]
    *** source: 11432833-Fig-5d
  *** rCyclinD1[35S] boundby[WB] rRb1[Ab] is detectable
    *** cells: none
    *** inhibited by: rRb1(mnr)"d22" [substitution]
    *** source: 8490963-Fig-1c
  *** rCyclinD1[35S] boundby[WB] rRb1[Ab] is detectable
    *** cells: none
    *** source: 8490963-Fig-1b
  *** CyclinD1[Ab] prot-exp[WB] is decreased itao Pin1 [AntiSense]
    *** cells: MCF7 in BMS
    *** source: 11432833-Fig-3b
  *** CyclinD1[Ab] prot-exp[WB] is decreased itao Tnik [RNAi]
    *** cells: SW480 in BMS
    *** source: 21710659-Fig-1a
  *** CyclinD1[Ab] prot-exp[WB] is detectable
    *** cells: HACAT in BMS "containing Tgfb1"
    *** reqs: Pdpk1 [RNAi]
    *** source: 17327236-Fig-7d
  *** CyclinD1[Ab] prot-exp[WB] is detectable
    *** cells: HELA in BMS "containing Tgfb1"
    *** reqs: Pdpk1 [RNAi]
    *** source: 17327236-Fig-7d
  *** CyclinD1[Ab] prot-exp[WB] is detectable
    *** cells: PANC1 in BMS
    *** does not req: EgfR [RNAi]
    *** source: 21573184-Fig-6b
  *** CyclinD1[Ab] prot-exp[WB] is detectable
    *** cells: PANC1 in BMS
    *** does not req: Src [RNAi]
    *** source: 21573184-Fig-6b
  *** CyclinD1[Ab] prot-exp[WB] is increased itpo xPin1
    *** cells: MCF7 in BMS
    *** source: 11432833-Fig-3a
  *** CyclinD1[Ab] prot-exp[WB] is increased itpo xPin1
    *** cells: MCF7 in BMS
    *** source: 11432833-Fig-3b
  *** CyclinD1[Ab] prot-exp[WB] is increased itpo xPin1
    *** cells: MCF7 in BMS
    *** source: 11533658-Fig-1c
  *** CyclinD1[Ab] prot-exp[WB] is increased itpo xPin1
    *** cells: T47D in BMS
    *** source: 11432833-Fig-3a
  *** CyclinD1[Ab] prot-exp[WB] is increased itpo xTsc2
    *** cells: LEF<Tsc2~null> in BMS
    *** unaffected by: xTsc2(S1371A/S1375A/S1337A/S1383A) [substitution]
    *** comment: aa numbers converted to Uniprot human canonical sequence
    *** source: 16959574-Fig-7f
  *** rCyclinD3[35S] boundby[WB] rRb1[Ab] is detectable
    *** cells: none
    *** inhibited by: rRb1(mnr)"d22" [substitution]
    *** source: 8490963-Fig-1c
  *** rCyclinE?[35S] boundby[WB] rRb1[Ab] is undetectable
    *** cells: none
    *** source: 8490963-Fig-1b
  *** xCyclinE?[Ab] snaggedby[WB] rCdkn1a[GST] is detectable
    *** cells: Ecoli<xCyclinE?> in BMS
    *** inhibited by: rCdkn1a(del(1-29)) [substitution]
    *** inhibited by: rCdkn1a(del(17-24)) [substitution]
    *** unaffected by: rCdkn1a(del(24-29)) [substitution]
    *** unaffected by: rCdkn1a(del(43-47)) [substitution]
    *** unaffected by: rCdkn1a(del(53-58)) [substitution]
    *** source: 8756624-Fig-1c
  *** CyclinEs[Ab] prot-exp[WB] is detectable
    *** cells: HELA in BMS
    *** unaffected by: Fbxw7 [KO]
    *** source: 15103331-Fig-5a
  *** CyclinEs[Ab] prot-exp[WB] is detectable
    *** cells: mSpCs in BMS
    *** partially reqs: Stat5a and/or Stat5b [DKO]
    *** source: 10072077-Fig-6a
  *** CyclinEs[Ab] prot-exp[WB] is increased itao Fbxw7 [RNAi]
    *** cells: HELA in BMS
    *** source: 15103331-Fig-4b
  *** CyclinEs[Ab] prot-exp[WB] is increased itao Skp2 [RNAi]
    *** cells: HELA in BMS
    *** source: 15103331-Fig-4b
  *** CyclinEs[Ab]IP IVKA(HistH1)[32P-ATP] is decreased itpo xTsc2
    *** cells: HELA in BMS
    *** reversed by: xAkt1(myr) [addition]
    *** source: 12167664-Fig-4b
  *** CyclinEs[Ab]IP IVKA(HistH1)[32P-ATP] is decreased itpo xTsc2(S939D/S981D/S993D/S1130D/S1132D/S1462D/S1798D)
    *** cells: HELA in BMS
    *** reversed by: xAkt1(myr) [addition]
    *** source: 12167664-Fig-4b
  *** CyclinG1-gene mRNA[RTPCR] is increased itpo xE4f1
    *** cells: U2OS in BMS
    *** reqs: Tp53 [RNAi]
    *** source: 17110336-Fig-5a
  *** CyclinG1-gene mRNA[RTPCR] is increased itpo xE4f1
    *** cells: U2OS in BMS
    *** unaffected by: xE4f1(del(41-85)) [substitution]
    *** source: 17110336-Fig-5a
  *** xCyld[tAb] copptby[WB] xIkba[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 12917690-Fig-2a
  *** xCyld[tAb] copptby[WB] xIkbb[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 12917690-Fig-2a
  *** xCyld[tAb] copptby[WB] xNemo[GST] is detectable
    *** cells: HEK293T in BMS
    *** source: 12917689-Fig-1a
  *** xCyld[tAb] copptby[WB] xNemo[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12917690-Fig-2a
  *** xCyld[tAb] phos[WBMS-PPase] is increased itpo xNemo
    *** cells: HEK293T in BMS
    *** unaffected by: xIkk2(mnr)"KD" [addition]
    *** source: 12917691-Fig-2b,S1
  *** rDab2[35S] boundby[WB] rSmad1[GST] is undetectable
    *** cells: none
    *** source: 11387212(D)
  *** rDab2[35S] boundby[WB] rSmad2[GST] is detectable
    *** cells: none
    *** source: 11387212(D)
  *** rDab2[35S] boundby[WB] rSmad3[GST] is detectable
    *** cells: none
    *** source: 11387212(D)
  *** rDab2[35S] boundby[WB] rSmad4[GST] is undetectable
    *** cells: none
    *** source: 11387212(D)
  *** xDab2[Ab] copptby[WB] xSmad2[tAb] is increased itpo xTgfbR1(mnr)"CA"
    *** cells: COS7 in BMS
    *** source: 11387212(D)
  *** xDab2[Ab] copptby[WB] xSmad3[tAb] is increased itpo xTgfbR1(mnr)"CA"
    *** cells: COS7 in BMS
    *** source: 11387212(D)
  *** xDab2[Ab] copptby[WB] xSmad4[tAb] is undetectable
    *** cells: COS7 in BMS
    *** unaffected by: xTgfbR1(mnr)"CA" [addition]
    *** source: 11387212(D)
  *** xDab2[Ab] copptby[WB] xSmad7[tAb] is undetectable
    *** cells: COS7 in BMS
    *** unaffected by: xTgfbR1(mnr)"CA" [addition]
    *** source: 11387212(D)
  *** Dapk1-gene mRNA[Northern] is increased itpo (xSmad2 + xSmad4)
    *** cells: HEP3B in BMLS
    *** source: 11740493-Fig-3e
  *** Dapk1-gene mRNA[Northern] is increased itpo (xSmad3 + xSmad4)
    *** cells: HEP3B in BMLS
    *** source: 11740493-Fig-3e
  *** Dapk1-gene promo-reporter[Luc] is increased itpo xTgfbR1(T407D)"CA"
    *** cells: SW4807<Smad4~null><xSmad4> in BMS
    *** reqs: xSmad4 [omission]
    *** source: 11740493-Fig-3c
*** Dbl--
  *** xDbl[tAb] copptby[WB] xTnk2[Ab] is detectable
    *** cells: HEK293 in BMLS
    *** source: 10652228-Fig-1f
  *** xDbl[tAb] snaggedby[WB] rRhoa(G17A)"NucFree"[GST] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-1
  *** xDbl[tAb]IP IVGefA(Rhoa)[3H-GDP] is increased itpo (xTnk2 + xCdc42(G12V)"CA")
    *** cells: HEK293 in BMLS
    *** reqs: xCdc42(G12V)"CA" [omission]
    *** source: 10652228-Fig-2a
  *** xDbl[tAb]IP IVGefA(Rhoa)[3H-GDP] is increased itpo xTnk2(L543F)"CA"
    *** cells: HEK293 in BMLS
    *** inhibited by: xTnk2(K214R)"KD" [substitution]
    *** source: 10652228-Fig-2a
  *** xDbl[tAb]IP Yphos[pYAb] is increased itpo (xTnk2 + xCdc42(G12V)"CA")
    *** cells: HEK293 in BMLS
    *** reqs: xCdc42(G12V)"CA" [omission]
    *** inhibited by: xTnk2(K214R)"KD" [substitution]
    *** source: 10652228-Fig-1a,1e
  *** xDbl[tAb]IP Yphos[pYAb] is increased itpo xTnk2(L543F)"CA"
    *** cells: HEK293 in BMLS
    *** source: 10652228-Fig-1d
*** Dbs--
  *** xDbs[tAb] snaggedby[WB] rCdc42(G15N)"NucFree"[GST] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-1
  *** xDbs[tAb] snaggedby[WB] rRac1(G15N)"NucFree"[GST] is undetectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-1
  *** xDbs[tAb] snaggedby[WB] rRhoa(G17A)"NucFree"[GST] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-1
  *** xDbs[tAb] snaggedby[WB] rRhog(G15N)"NucFree"[GST] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-1
  *** xDdit3(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xKras(G12V)"CA"
    *** cells: HTTA in BMS
    *** inhibited by: xRig1 [addition]
    *** unaffected by: xRig1(del(Cterm)) [addition]
    *** source: 16005186-Fig-6a
  *** xDdit3(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMekk3
    *** cells: HEK293 in BMS
    *** source: 16153868-Fig-2d
  *** xDdit3(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMkk3
    *** cells: HTTA in BMS
    *** unaffected by: xRig1 [addition]
    *** unaffected by: xRig1(del(Cterm)) [addition]
    *** source: 16005186-Fig-6b
  *** xDdit3(TAD)[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xMavs
    *** cells: HEK293 in BMS
    *** source: 16153868-Fig-2d
  *** xDdit3(TAD)[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xPeli1
    *** cells: HEK293 in BMS
    *** source: 12804775-Fig-2b
  *** xDdit3(TAD)[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xPeli2
    *** cells: HEK293 in BMS
    *** source: 12804775-Fig-2a
*** Ddit4--
  *** xDdit4[tAb] copptby[WB] xYwhaz[tAb] is detectable
    *** cells: HEK293T<xDdit4><xYwhaz> in BMS
    *** inhibited by: xDdit4(mnr)"RPAA" [substitution]
    *** source: 18198340-Fig-5c
  *** xDdit4[tAb] snaggedby[WB] rYwhab[GST] is detectable
    *** cells: HEK293T<xDdit4> in BMS
    *** comment: inhibited by addition of peptide PHCVPRDLSWLDLEANMCLP
    *** source: 18198340-Fig-5b
  *** xDdit4[tAb] snaggedby[WB] rYwhab[GST] is detectable
    *** cells: HEK293T<xDdit4> in BMS
    *** inhibited by: xDdit4(mnr)"delC" [substitution]
    *** inhibited by: xDdit4(mnr)"RPAA" [substitution]
    *** source: 18198340-Fig-5a
  *** xDdx3x[tAb] copptby[WB] xIkke[tAb] is detectable
    *** cells: HEK293T<xDdx3x><xIkke> in BMS
    *** source: 18636090-Fig-6f
  *** rDdx41[GST] boundby[WB] c-diGMP[biotin] is detectable
    *** cells: none
    *** inhibited by: c-diAMP [addition]
    *** partially inhibited by: GMP [addition]
    *** inhibited by: AMP [addition]
    *** unaffected by: GTP [addition]
    *** unaffected by: ATP [addition]
    *** source: 23142775-Fig-S3c
  *** rDdx41[GST] boundby[WB] c-diGMP[biotin] is detectable
    *** cells: none
    *** partially inhibited by: c-diAMP [addition]
    *** partially inhibited by: Poly-dAdT-dTdA [addition]
    *** unaffected by: PolyIC [addition]
    *** source: 23142775-Fig-3d
  *** rDdx41[GST] boundby[WB] c-diGMP[biotin] is detectable
    *** cells: none
    *** source: 23142775-Fig-3c
  *** rDdx41[GST] boundby[WB] c-diGMP[biotin] is detectable
    *** cells: none
    *** source: 23142775-Fig-S3b
  *** xDdx41[tAb] snaggedby[WB] c-diAMP[biotin] is detectable
    *** cells: HEK293T<xDdx41> in BMS
    *** source: 23142775-Fig-S3a
  *** xDdx41[tAb] snaggedby[WB] c-diAMP[biotin] is detectable
    *** cells: HEK293T<xDdx41> in BMS
    *** source: 23142775-Fig-S3d
  *** xDdx41[tAb] snaggedby[WB] c-diAMP[biotin] is detectable
    *** cells: HEK293T<xDdx41> in BMS
    *** unaffected by: xDdx41(183-623) [substitution]
    *** inhibited by: xDdx41(408-623) [substitution]
    *** unaffected by: xDdx41(1-536) [substitution]
    *** unaffected by: xDdx41(1-407) [substitution]
    *** source: 23142775-Fig-4c
  *** xDdx41[tAb] snaggedby[WB] c-diGMP[biotin] is detectable
    *** cells: HEK293T<xDdx41> in BMS
    *** source: 23142775-Fig-3a
  *** xDdx41[tAb] snaggedby[WB] c-diGMP[biotin] is detectable
    *** cells: HEK293T<xDdx41> in BMS
    *** unaffected by: xDdx41(183-623) [substitution]
    *** inhibited by: xDdx41(408-623) [substitution]
    *** unaffected by: xDdx41(1-536) [substitution]
    *** unaffected by: xDdx41(1-407) [substitution]
    *** source: 23142775-Fig-4c
  *** xDedd[tAb] copptby[WB] xNod1[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 10329646(D)
*** Deptor--
  *** Deptor-gene mRNA[RTPCR] is detectable
    *** cells: RPMI8226 in BMS
    *** reqs: Maf [RNAi]
    *** source: 19446321-Fig-6i
  *** Deptor-gene mRNA[RTPCR] is increased itao Raptor [RNAi]
    *** cells: HELA in BMS
    *** source: 19446321-Fig-4g
  *** Deptor-gene mRNA[RTPCR] is increased itao Rictor [RNAi]
    *** cells: HELA in BMS
    *** source: 19446321-Fig-4g
  *** Deptor[Ab] copptby[WB] Rictor[Ab] is detectable
    *** cells: HEK293E in BMS
    *** comment: inhibited by washing ppt with high salt
    *** source: 19446321-Fig-1d
  *** Deptor[Ab] copptby[WB] Rictor[Ab] is detectable
    *** cells: HELA in BMS
    *** source: 19446321-Fig-1e
  *** Deptor[Ab] prot-exp[WB] is decreased itao Tsc2 [KO]
    *** cells: mEFs in BMS
    *** source: 19446321-Fig-4d
  *** Deptor[Ab] prot-exp[WB] is detectable
    *** cells: RPMI8226 in BMS
    *** partially reqs: Pten [RNAi]
    *** source: 19446321-Fig-S2
  *** Deptor[Ab] prot-exp[WB] is detectable
    *** cells: RPMI8226 in BMS
    *** reqs: Maf [RNAi]
    *** source: 19446321-Fig-6j
  *** xDeptor[tAb] copptby[WB] Rictor[Ab] is detectable
    *** cells: HEK293T<xDeptor> in BMS
    *** enhanced by: xDeptor(dig)"13ST/A" [substitution]
    *** source: 19446321-Fig-5a
  *** xDeptor[tAb] copptby[WB] xRap2a[tAb] is undetectable
    *** cells: HEK293E<xRap2a><xDeptor> in BMS
    *** source: 19446321-Fig-1g
*** Dhx9--
  *** Dhx9[Ab] colocwith[IHC] Stau1[Ab] is detectable
    *** cells: SHSY5Y in BMS "differentiated with retinoic acid for 7 days"
    *** source: 15121898(D)
  *** Dhx9[Ab] copptby[WB] xStau1[tAb] is detectable
    *** cells: HEK293T in BMS "infected with vaccinia vTf7-3 virus"
    *** source: 15121898(D)
  *** Dhx9[MS] copptby[WB] xStau1[tAb] is detectable
    *** cells: HEK293T in BMS "infected with vaccinia vTf7-3 virus"
    *** source: 15121898(D)
  *** rDiras2 GDP-dissociation[Mant-GDP] is unchanged by rRasGef1a
    *** cells: none
    *** source: 19645719-Fig-1c
  *** rDiras2 GDP-dissociation[Mant-GDP] is unchanged by rRasGef1b
    *** cells: none
    *** source: 19645719-Fig-1c
  *** xDixdc1[tAb] copptby[WB] xRac1[tAb] is detectable
    *** cells: HEK293T<xDvl2> in BMS
    *** source: 15262978-Fig-2c
  *** xDnajc3[Ab] copptby[WB] xTirap[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 11526399(D)
  *** xDnm1[tAb] copptby[WB] xEndA3[Ab] is detectable
    *** cells: HEK293T<xDnm1><xEndA3> in BMS
    *** source: 11894096-Fig-S1
*** Dock1--
  *** Dock1[Ab] copptby[WB] Crk[Ab] is detectable
    *** cells: HELA in BMS
    *** source: 8657152-Fig-7
*** Dok1--
  *** rDok1[32P] phos[32P-ATP] is increased by rInsR
    *** cells: none
    *** comment: the origin of the pInsR is unclear
    *** inhibited by: rDok1(Y362F) [substitution]
    *** unaffected by: rDok1(Y377F) [substitution]
    *** inhibited by: rDok1(Y398F) [substitution]
    *** unaffected by: rDok1(Y402F) [substitution]
    *** unaffected by: rDok1(Y409F) [substitution]
    *** unaffected by: rDok1(Y449F) [substitution]
    *** source: 11551902-Fig-4a
  *** rDok1[32P] phos[32P-ATP] is increased by rInsR
    *** cells: none
    *** comment: the origin of the rInsR is unclear
    *** inhibited by: rInsR(mnr)"KD" [substitution]
    *** inhibited by: rInsR(Y1162F/Y1163F) [substitution]
    *** source: 11551902-Fig-1a
  *** Dok1[Ab]IP Yphos[pYAb] is detectable
    *** cells: mEFs<Src~null><Yes1~null><Fyn~null><xSrc> in BMLS
    *** bkg reqs: xSrc [omission]
    *** source: 14967142-Fig-2c
  *** Dok1[Ab]IP Yphos[pYAb] is increased itpo xCsk(mnr)"KD"
    *** cells: CHO<xInsR> in BMLS
    *** inhibited by: xCsk [substitution]
    *** source: 10202139-Fig-2a
  *** xDok1[tAb]IP Yphos[pYAb] is decreased itpo xPtprh
    *** cells: HEK293 in BMS
    *** reversed by: rPtprh(C1022S)"CIA" [substitution]
    *** reversed by: rPtprh(D988A)"CIA" [substitution]
    *** source: 11278335-Fig-3a
  *** xDok1[tAb]IP Yphos[pYAb] is detectable
    *** cells: CHO<xInsR> in BMLS
    *** inhibited by: xDok1(del(PH-domain)) [substitution]
    *** source: 10202139-Fig-4a
  *** xDok1[tAb]IP Yphos[pYAb] is detectable
    *** cells: CHO<xInsR> in BMLS
    *** inhibited by: xDok1(Y361F) [substitution]
    *** source: 10202139-Fig-6
*** Dok2--
  *** xDok2[Ab] copptby[WB] xAbl1[Ab] is detectable
    *** cells: COS1<xDok2><xAbl1> in BMLS
    *** inhibited by: xAbl1(mnr)"KD" [substitution]
    *** inhibited by: xAbl1(mnr)"dSH2" [substitution]
    *** source: 12777393-Fig-3a
  *** xDok2[Ab]IP Yphos[pYAb] is increased itpo xHck
    *** cells: HEK293T in BMS
    *** unaffected by: xHck(Y499F) [substitution]
    *** source: 10428862-Fig-3a
  *** xDok2[Ab]IP Yphos[pYAb] is increased itpo xLyn
    *** cells: HEK293T in BMS
    *** unaffected by: xLyn(Y508F) [substitution]
    *** source: 10428862-Fig-3a
  *** xDok2[Ab]IP Yphos[pYAb] is increased itpo xSrc(Y527F)
    *** cells: HEK293T in BMS
    *** source: 10428862-Fig-3a
  *** xDok2[tAb] copptby[WB] xSrc[Ab] is detectable
    *** cells: COS1 in BMLS
    *** unaffected by: Egf (5 min) [stim]
    *** source: 15831486-Fig-7a
  *** xDusp1[XFP] locatedin(nucleus)[IHC] is detectable
    *** cells: COS1<xDusp1> in BMS
    *** unaffected by: xErk2 [addition]
    *** source: 15713638-Fig-10b
  *** rDusp5[Ab] boundby[WB] rErk2[GST] is detectable
    *** cells: none
    *** enhanced by: rDusp5(D232N) [substitution]
    *** source: 15713638-Fig-1c
  *** Dusp5[Ab] infraction(nuclear)[WB] is detectable
    *** cells: NIH3T3 in BMS "stimulated with serum"
    *** source: 15713638-Fig-6b
  *** xDusp5[XFP] locatedin(nucleus)[IHC] is detectable
    *** cells: COS1<xDusp5> in BMS
    *** inhibited by: xDusp5(R12G/K13A/R16G/K17A) [substitution]
    *** partially inhibited by: xDusp5(R53A/R54A) [substitution]
    *** source: 15713638-Fig-7
  *** xDusp5[XFP] locatedin(nucleus)[IHC] is detectable
    *** cells: COS1<xDusp5> in BMS
    *** partially inhibited by: xDusp5(194-384) [substitution]
    *** unaffected by: xDusp5(1-193) [substitution]
    *** unaffected by: xDusp5(1-127) [substitution]
    *** unaffected by: xDusp5(1-61) [substitution]
    *** source: 15713638-Fig-6a
  *** xDusp5[XFP] locatedin(nucleus)[IHC] is detectable
    *** cells: COS1<xDusp5><xErk2> in BMS
    *** inhibited by: xDusp5(R12G/K13A/R16G/K17A) [substitution]
    *** source: 15713638-Fig-10a
  *** xDusp5[XFP] locatedin(nucleus)[IHC] is detectable
    *** cells: NIH3T3<xDusp5><xErk2> in BMS
    *** unaffected by: xDusp5(R12G/K13A/R16G/K17A) [substitution]
    *** unaffected by: xDusp5(R53A/R54A) [substitution]
    *** source: 15713638-Fig-9b
  *** xDusp5[XFP] locatedin(nucleus)[IHC] is detectable
    *** cells: NIH3T3<xDusp5><xJnk1> in BMS
    *** source: 15713638-Fig-9b
  *** xDusp5[XFP] locatedin(nucleus)[IHC] is detectable
    *** cells: NIH3T3<xDusp5><xP38a> in BMS
    *** source: 15713638-Fig-9b
  *** xDusp6(1-221)[XFP] locatedin(cytoplasm)[IHC] is detectable
    *** cells: COS1<xDusp6(1-221)><xErk2> in BMS
    *** source: 15269220-Fig-10a
  *** xDusp6(1-221)[XFP] locatedin(cytoplasm)[IHC] is detectable
    *** cells: HELA<xDusp6(1-221)> in BMS
    *** source: 15269220-Fig-4
  *** xDusp6(C293S)[XFP] locatedin(cytoplasm)[IHC] is detectable
    *** cells: COS1<xDusp6(C293S)><xErk2> in BMS
    *** source: 15269220-Fig-10a
  *** xDusp6(C293S/L167A/L170A)[XFP] locatedin(nucleus-cytoplasm)[IHC] is detectable
    *** cells: COS1<xDusp6(C293S/L167A/L170A)><xErk2> in BMS
    *** source: 15269220-Fig-10a
  *** xDusp6(C293S/R64A/R65A)[XFP] locatedin(nucleus)[IHC] is detectable
    *** cells: COS1<xDusp6(C293S/R64A/R65A)><xErk2> in BMS
    *** source: 15269220-Fig-10a
  *** xDusp6(L117A/L118A/L119A)[XFP] locatedin(cytoplasm)[IHC] is detectable
    *** cells: HELA<xDusp6(L117A/L118A/L119A)> in BMS
    *** source: 15269220-Fig-5b
  *** xDusp6(L167A/L170A)[XFP] locatedin(nucleus)[IHC] is detectable
    *** cells: HELA<xDusp6(L167A/L170A)> in BMS
    *** source: 15269220-Fig-5b
  *** xDusp6(L167A/L170A)[XFP] locatedin(nucleus)[IHC] is detectable
    *** cells: HELA<xDusp6(L167A/L170A)> in BMS
    *** unaffected by: LMB [addition]
    *** source: 15269220-Fig-9b
  *** xDusp6(R64A/R65A)[XFP] locatedin(cytoplasm)[IHC] is detectable
    *** cells: HELA<xDusp6(L117A/L118A/L119A)> in BMS
    *** source: 15269220-Fig-8b
  *** xDusp6[Ab] infraction(cytoplasmic)[WB] is detectable
    *** cells: HELA<xDusp6> in BMS
    *** source: 15269220-Fig-1d
  *** Dusp6[Ab] infraction(cytoplasmic)[WB] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 15269220-Fig-1c
  *** xDusp6[Ab] infraction(cytoplasmic)[WB] is detectable
    *** cells: NIH3T3<xDusp6> in BMS
    *** source: 15269220-Fig-1c
  *** xDusp6[tAb] locatedin(cytoplasm)[IHC] is detectable
    *** cells: CCL39<xDusp6> in BMLS "treated with serum for 3 hr"
    *** unaffected by: xDusp6(C293S) [substitution]
    *** source: 9927426-Fig-1a
  *** xDusp6[XFP] locatedin(cytoplasm)[IHC] is detectable
    *** cells: COS1<xDusp6><xErk2> in BMS
    *** source: 15269220-Fig-10a
  *** xDusp6[XFP] locatedin(cytoplasm)[IHC] is detectable
    *** cells: HELA<xDusp6> in BMS
    *** source: 15269220-Fig-1a
  *** xDusp6[XFP] locatedin(cytoplasm)[IHC] is detectable
    *** cells: HELA<xDusp6> in BMS
    *** source: 15269220-Fig-5b
  *** xDusp6[XFP] locatedin(cytoplasm)[IHC] is detectable
    *** cells: NIH3T3<xDusp6> in BMS
    *** source: 15269220-Fig-1b
  *** xDvl?[Ab] copptby[WB] xAdrbk?[tAb] is undetectable
    *** cells: HEK293<xAdrbk?><xDvl?> in BMS
    *** source: 20460648-Fig-S6
  *** xDvl?[tAb] copptby[WB] xGnb1[tAb] is detectable 
    *** cells: HEK293<xDvl?><xGnb1><xGng2> in BMS
    *** source: 20460648-Fig-6d
*** Dvl1--
  *** rDvl1(1-82)[GST] boundby[WB] rDvl3[MalBP] is detectable
    *** cells: none
    *** inhibited by: rDvl1(140-670) [substitution]
    *** source: 10330181-Fig-2b
  *** rDvl1(1-82)[GST] boundby[WB] rDvl3[MalBP] is detectable
    *** cells: none
    *** unaffected by: rDvl3(1-80) [substitution]
    *** source: 10330181-Fig-2b
  *** rDvl1(1-82)[tAb] oligomerization[2TagPpt] is detectable
    *** cells: none
    *** source: 10330181-Fig-3b
  *** xDvl1(337-670)[Ab] copptby[WB] Apc[Ab] is detectable
    *** cells: HEK293T<xDvl1(337-670)> in BMS
    *** source: 20224554-Fig-S16b
  *** xDvl1(337-670)[Ab] copptby[WB] Apc[Ab] is detectable
    *** cells: HEK293T<xDvl1(337-670)> in BMS
    *** source: 20224554-Fig-S16d
  *** xDvl1[Ab] copptby[WB] Apc[Ab] is detectable
    *** cells: COS7<xDvl1> in BMS
    *** inhibited by: xDvl1(1-250)"DIX" [substitution]
    *** inhibited by: xDvl1(201-371)"PDZ" [substitution]
    *** unaffected by: xDvl1(337-670)"DEP" [substitution]
    *** inhibited by: xDvl1(1-398) [substitution]
    *** source: 20224554-Fig-2d
  *** xDvl1[tAb] copptby[WB] Fak1[Ab] is detectable
    *** cells: COS7<xDvl1> in BMS
    *** inhibited by: xDvl1(1-250)"DIX" [substitution]
    *** inhibited by: xDvl1(201-371)"PDZ" [substitution]
    *** unaffected by: xDvl1(337-670)"DEP" [substitution]
    *** inhibited by: xDvl1(1-398) [substitution]
    *** source: 20224554-Fig-5g
  *** xDvl1[tAb] copptby[WB] xDvl3[tAb] is detectable
    *** cells: COS<xDvl1><xDvl3> in BMS
    *** unaffected by: xDvl1(140-670) [substitution]
    *** source: 10330181-Fig-2a
  *** xDvl1[tAb] copptby[WB] xFrat1[tAb] is detectable
    *** cells: COS<xDvl1><xFrat1> in BMS
    *** inhibited by: xDvl1(1-250) [substitution]
    *** inhibited by: xDvl1(del(228-250)) [substitution]
    *** inhibited by: xDvl1(del(337-695)) [substitution]
    *** unaffected by: xDvl1(1-544) [substitution]
    *** unaffected by: xDvl1(140-695) [substitution]
    *** unaffected by: xDvl1(del(141-227)) [substitution]
    *** unaffected by: xDvl1(del(251-336)) [substitution]
    *** source: 12556519-Fig-1a
  *** xDvl1[tAb] copptby[WB] xFrat1[tAb] is increased itpo xCsnk1e
    *** cells: COS<xDvl1><xFrat1> in BMS
    *** inhibited by: xCsnk1(mnr)"KD" [substitution]
    *** source: 12556519-Fig-2a
  *** xDvl1[tAb] locatedin(cellmembrane)[IHC] is increased itpo xFzd9
    *** cells: HEK293T in BMS
    *** source: 12138115-Fig-1a
  *** xDvl1[tAb] locatedin(cellmembrane)[IHC] is increased itpo xFzd9
    *** cells: HEK293T in BMS
    *** unaffected by: xFzd9(1-554)"C38" [substitution]
    *** unaffected by: xFzd9(del(58-174))"N" [substitution]
    *** source: 12138115-Fig-4a
  *** xDvl1[tAb] locatedin(cellmembrane)[IHC] is increased itpo xFzd9
    *** cells: HEK293T<xAxin1><xDvl1> in BMS
    *** unaffected by: xFzd9(1-554)"C38" [substitution]
    *** unaffected by: xFzd9(del(58-174))"N" [substitution]
    *** source: 12138115-Fig-7b
  *** xDvl1[tAb] oligomerization[2TagPpt] is detectable
    *** cells: COS<xDvl1> in BMS
    *** source: 10330181-Fig-3a
  *** xDvl1[tAb] phos[WBMS-PPase] is increased itpo xFzd9
    *** cells: HEK293T in BMS
    *** source: 12138115-Fig-1b
  *** xDvl1[tAb] phos[WBMS] is increased itpo xFzd9
    *** cells: HEK293T in BMS
    *** unaffected by: xFzd9(1-587)"C5" [substitution]
    *** unaffected by: xFzd9(1-577)"C15" [substitution]
    *** unaffected by: xFzd9(1-566)"C26" [substitution]
    *** unaffected by: xFzd9(1-554)"C38" [substitution]
    *** source: 12138115-Fig-4b
  *** xDvl1[tAb] phos[WBMS] is increased itpo xFzd9
    *** cells: HEK293T in BMS
    *** unaffected by: xFzd9(del(58-174))"N" [substitution]
    *** source: 12138115-Fig-6a
*** Dvl2--
  *** Dvl2[Ab] copptby[WB] Apc[Ab] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xDvl1(337-670) [addition]
    *** source: 20224554-Fig-S16b
  *** Dvl2[Ab] copptby[WB] Apc[Ab] is detectable
    *** cells: MDCK in BMS
    *** source: 20224554-Fig-2b
  *** Dvl2[Ab] copptby[WB] xApc(221-958)[tAb] is detectable
    *** cells: COS7<xApc(221-958)> in BMS
    *** inhibited by: xApc(1-220)"NT" [substitution]
    *** inhibited by: xApc(959-1338)"M2" [substitution]
    *** inhibited by: xApc(1211-2075)"M3" [substitution]
    *** inhibited by: xApc(2079-2843)"CT" [substitution]
    *** source: 20224554-Fig-2e
  *** Dvl2[Ab] locatedin(cellmembrane)[IHC] is increased itpo xCsnk1e
    *** cells: COS1<xRor2> in BMS
    *** inhibited by: xCsnk1e(mnr)"KD" [substitution]
    *** source: 20215527-Fig-3a
  *** Dvl2[Ab] locatedin(cellmembrane)[IHC] is increased itpo xCsnk1e
    *** cells: COS1<xRor2> in BMS
    *** source: 20215527-Fig-2g
  *** xDvl2[tAb] copptby[WB] Fak1[Ab] is detectable
    *** cells: COS7<xDvl2> in BMS
    *** unaffected by: xDvl2(mnr)"delDEP" [substitution]
    *** inhibited by: xDvl2(1-509) [substitution]
    *** unaffected by: xDvl2(506-736) [substitution]
    *** source: 20224554-Fig-S14b
  *** xDvl2[tAb] copptby[WB] xApc(221-958)[tAb] is detectable
    *** cells: COS7<xDvl2><xApc(221-958)> in BMS
    *** partially inhibited by: xApc(221-731) [substitution]
    *** inhibited by: xApc(221-597) [substitution]
    *** inhibited by: xApc(221-458) [substitution]
    *** source: 20224554-Fig-S15a
  *** xDvl2[tAb] copptby[WB] xRac1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xDixdc1 [addition]
    *** source: 15262978-Fig-2c
*** Dvl3--
  *** xDvl3[Ab] copptby[WB] xPpm1a[Ab] is detectable
    *** cells: COS1<xDvl3><xPpm1a> in BMS
    *** source: 10644691-Fig-1a
  *** xDvl3[tAb] copptby[WB] xRor2[tAb] is increased itpo xCsnk1e
    *** cells: COS7<xDvl3><xRor2> in BMS
    *** inhibited by: xCsnk1e(mnr)"KD" [substitution]
    *** source: 20215527-Fig-1d
  *** xDvl3[tAb] copptby[WB] xRor2[tAb] is increased itpo xCsnk1e
    *** cells: COS7<xDvl3><xRor2> in BMS
    *** inhibited by: xDvl3(mnr)"4" [substitution]
    *** inhibited by: xDvl3(mnr)"7" [substitution]
    *** source: 20215527-Fig-1d
  *** xDvl3[tAb] copptby[WB] xRor2[tAb] is increased itpo xCsnk1e
    *** cells: COS7<xDvl3><xRor2> in BMS
    *** source: 20215527-Fig-1c
  *** xDvl3[tAb] copptby[WB] xRor2[tAb] is unchanged itpo xCsnk2a?
    *** cells: COS7<xDvl3><xRor2> in BMS
    *** unaffected by: xCsnk2a?(mnr)"KD" [substitution]
    *** source: 20215527-Fig-1d
  *** xDvl3[tAb] copptby[WB] xRor2[tAb] is unchanged itpo xMark2
    *** cells: COS7<xDvl3><xRor2> in BMS
    *** unaffected by: xMark2(mnr)"KD" [substitution]
    *** source: 20215527-Fig-1d
*** E2f1--
  *** xE2f1[32P] oligo-binding[EMSA] is increased itpo xTfdp1
    *** cells: C33A<xE2f1> in BMS
    *** comment: upshifted by coexpression of xRb1
    *** comment: unaffected by coexpression of xRbl1
    *** source: 7739537-Fig-3
  *** xE2f1[32P] oligo-binding[EMSA] is increased itpo xTfdp2
    *** cells: C33A<xE2f1> in BMS
    *** comment: upshifted by coexpression of xRb1
    *** comment: unaffected by coexpression of xRbl1
    *** source: 7739537-Fig-3
  *** rE2f1[32P] phos[32P-ATP] is increased by (rCyclinA? + rCdk2)
    *** cells: none
    *** comment: rCyclinA? and rCdk2 were expressed in SF9 cells and purified by chromatograph
    *** source: 9003781-Fig-1c
  *** rE2f1[32P] phos[32P-ATP] is increased by xAtm[tAb]IP
    *** cells: none
    *** IPfrom: HEK293T<xAtm> in BMS
    *** inhibited by: rE2f1(S31A) [substitution]
    *** source: 11459832-Fig-5b
  *** rE2f1[32P] phos[32P-ATP] is increased by xAtm[tAb]IP
    *** cells: none
    *** IPfrom: HEK293T<xAtm> in BMS
    *** partially inhibited by: xAtm(mnr)"KD" [substitution]
    *** source: 11459832-Fig-4a
  *** rE2f1[32P] phos[32P-ATP] is increased by xAtr[tAb]IP
    *** cells: none
    *** IPfrom: HEK293T<xAtr> in BMS
    *** inhibited by: rE2f1(S31A) [substitution]
    *** source: 11459832-Fig-5b
  *** rE2f1[32P] phos[32P-ATP] is increased by xAtr[tAb]IP
    *** cells: none
    *** IPfrom: HEK293T<xAtr> in BMS
    *** inhibited by: xAtr(mnr)"KD" [substitution]
    *** source: 11459832-Fig-4b
  *** rE2f1[32P] phos[32P-ATP] is unchanged by (rCyclinD1 + rCdk4)
    *** cells: none
    *** comment: rCyclinD1 and rCdk4 were expressed in SF9 cells and purified by chromatograph
    *** source: 9003781-Fig-1c
  *** rE2f1[32P] phos[32P-ATP] is unchanged by (rCyclinE? + rCdk2)
    *** cells: none
    *** comment: rCyclinE? and rCdk2 were expressed in SF9 cells and purified by chromatograph
    *** source: 9003781-Fig-1c
  *** rE2f1[32P] phos[32P-ATP] is unchanged by rJnk2
    *** cells: none
    *** source: 12058026-Fig-1c
  *** E2f1[Ab] copptby[WB] CyclinA1[Ab] is detectable
    *** cells: NB4 in BMS
    *** source: 10022926-Fig-2c
  *** E2f1[Ab] copptby[WB] Rb1[Ab] is detectable
    *** cells: WI38 in BMS
    *** source: 9003781-Fig-6
  *** E2f1[Ab] copptby[WB] Rb1{phos(S780)}[phosAb] is undetectable
    *** cells: WI38 in BMS
    *** source: 9003781-Fig-6
  *** xE2f1[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: CHOC400<xE2f1> in BMS
    *** inhibited by: xE2f1(Y411C) [substitution]
    *** inhibited by: xE2f1(1-191) [substitution]
    *** inhibited by: xE2f1(1-416) [substitution]
    *** inhibited by: xE2f1(1-284) [substitution]
    *** inhibited by: xE2f1(1-374) [substitution]
    *** source: 8832394-Table-1b
  *** xE2f1[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: CHOC400<xE2f1> in BMS
    *** source: 8832394-Fig-1 
  *** E2f1[Ab] snaggedby[WB] oligo[biotin] is detectable
    *** cells: KIT225 in BMS "containing IL2"
    *** oligo: "E2A" 5-TAGTTTTCGCGCTTAAATTTGAGAAAGGGCGCGAAACTAGTC-3
    *** source: 10373522-Fig-3b
  *** E2f1[Ab] snaggedby[WB] oligo[biotin] is detectable
    *** cells: KIT225 in BMS "containing IL2"
    *** oligo: "E2A" 5-TAGTTTTCGCGCTTAAATTTGAGAAAGGGCGCGAAACTAGTC-3
    *** unaffected by: Rapamycin [pretreatment]
    *** source: 10373522-Fig-3c
  *** xE2f1[tAb] copptby[WB] Smad4[Ab] is undetectable
    *** cells: COS1 in BMS
    *** unaffected by: Tgfb1 (1 hr) [stim]
    *** source: 12150994-Fig-3a
  *** xE2f1[tAb] copptby[WB] Smad23s[Ab] is undetectable
    *** cells: COS1 in BMS
    *** unaffected by: Tgfb1 (1 hr) [stim]
    *** source: 12150994-Fig-3a
  *** xE2f1[tAb]IP phos[32Pi] is detectable
    *** cells: HEK293T<xE2f1> in BMS
    *** enhanced by: xAtm [addition]
    *** inhibited by: xAtm(mnr)"KD" [addition]
    *** source: 11459832-Fig-6b
  *** E2f2-gene mRNA[RTPCR] is decreased itpo xHbp1
    *** cells: HEK293 in BMLS
    *** reversed by: xMyc [addition]
    *** source: 20008325-Fig-3f
  *** E2f2-gene mRNA[RTPCR] is increased itao Hbp1 [RNAi]
    *** cells: HEK293 in BMLS
    *** source: 20008325-Fig-3e
  *** E2f2-gene mRNA[RTPCR] is increased itao Ppp2ca [RNAi]
    *** cells: HEK293 in BMLS
    *** source: 16537924-Fig-7d
  *** E2f2-gene mRNA[RTPCR] is increased itao Ppp2r5a [RNAi]
    *** cells: HEK293 in BMLS
    *** source: 16537924-Fig-7d
  *** E2f2-gene mRNA[RTPCR] is increased itpo xMyc
    *** cells: HEK293 in BMLS
    *** bkg inhibited by: xHbp1 [addition]
    *** source: 20008325-Fig-3f
  *** E2f2-gene promo-reporter[Luc] is increased itpo xMyc
    *** cells: REF52 in BMLS
    *** inhibited by: xHbp1 [addition]
    *** source: 20008325-Fig-2b
  *** xE2f2[32P] oligo-binding[EMSA] is increased itpo xTfdp1
    *** cells: C33A<xE2f2> in BMS
    *** comment: upshifted by coexpression of xRb1
    *** comment: unaffected by coexpression of xRbl1
    *** source: 7739537-Fig-3
  *** xE2f2[32P] oligo-binding[EMSA] is increased itpo xTfdp2
    *** cells: C33A<xE2f2> in BMS
    *** comment: upshifted by coexpression of xRb1
    *** comment: unaffected by coexpression of xRbl1
    *** source: 7739537-Fig-3
  *** rE2f2[32P] phos[32P-ATP] is unchanged by xAtm[tAb]IP
    *** cells: none
    *** IPfrom: HEK293T<xAtm> in BMS
    *** source: 11459832-Fig-4a
  *** rE2f2[32P] phos[32P-ATP] is unchanged by xAtr[tAb]IP
    *** cells: none
    *** IPfrom: HEK293T<xAtr> in BMS
    *** source: 11459832-Fig-4b
  *** xE2f2[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: CHOC400<xE2f2> in BMS
    *** source: 8832394-Fig-1 
  *** xE2f3[32P] oligo-binding[EMSA] is increased itpo xTfdp1
    *** cells: C33A<xE2f3> in BMS
    *** comment: upshifted by coexpression of xRb1
    *** comment: unaffected by coexpression of xRbl1
    *** source: 7739537-Fig-3
  *** xE2f3[32P] oligo-binding[EMSA] is increased itpo xTfdp2
    *** cells: C33A<xE2f3> in BMS
    *** comment: upshifted by coexpression of xRb1
    *** comment: unaffected by coexpression of xRbl1
    *** source: 7739537-Fig-3
  *** rE2f3[32P] phos[32P-ATP] is unchanged by xAtm[tAb]IP
    *** cells: none
    *** IPfrom: HEK293T<xAtm> in BMS
    *** source: 11459832-Fig-4a
  *** rE2f3[32P] phos[32P-ATP] is unchanged by xAtr[tAb]IP
    *** cells: none
    *** IPfrom: HEK293T<xAtr> in BMS
    *** source: 11459832-Fig-4b
  *** xE2f3[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: CHOC400<xE2f3> in BMS
    *** source: 8832394-Fig-1 
*** E2f4--
  *** E2f4[Ab] copptby[WB] Smad23s[Ab] is detectable
    *** cells: HACAT in BMS
    *** unaffected by: Tgfb1 (1 hr) [stim]
    *** source: 12150994-Fig-3b
  *** xE2f4[Ab] locatedin(cytoplasm)[IHC] is detectable
    *** cells: CHOC400<xE2f4> in BMS
    *** source: 8832394-Fig-1 
  *** xE2f4[Ab] locatedin(nucleus)[IHC] is increased itpo xRbl1
    *** cells: CHOC400<xE2f4> in BMS
    *** source: 8832394-Table-3
  *** xE2f4[Ab] locatedin(nucleus)[IHC] is increased itpo xRbl2
    *** cells: CHOC400<xE2f4> in BMS
    *** source: 8832394-Table-3
  *** xE2f4[Ab] locatedin(nucleus)[IHC] is increased itpo xTfdp2
    *** cells: CHOC400<xE2f4> in BMS
    *** source: 8832394-Table-1a
  *** xE2f4[Ab] locatedin(nucleus)[IHC] is unchanged itpo xRb1
    *** cells: CHOC400<xE2f4> in BMS
    *** source: 8832394-Table-3
  *** xE2f4[Ab] locatedin(nucleus)[IHC] is unchanged itpo xTfdp1
    *** cells: CHOC400<xE2f4> in BMS
    *** source: 8832394-Table-1a
  *** xE2f4[tAb] copptby[WB] Smad4[Ab] is undetectable
    *** cells: COS1 in BMS
    *** unaffected by: Tgfb1 (1 hr) [stim]
    *** source: 12150994-Fig-3a
  *** xE2f4[tAb] copptby[WB] Smad23s[Ab] is detectable
    *** cells: COS1 in BMS
    *** unaffected by: Tgfb1 (1 hr) [stim]
    *** source: 12150994-Fig-3a
*** E2f5--
  *** xE2f5[tAb] copptby[WB] Smad4[Ab] is undetectable
    *** cells: COS1 in BMS
    *** unaffected by: Tgfb1 (1 hr) [stim]
    *** source: 12150994-Fig-3a
  *** xE2f5[tAb] copptby[WB] Smad23s[Ab] is detectable
    *** cells: COS1 in BMS
    *** unaffected by: Tgfb1 (1 hr) [stim]
    *** source: 12150994-Fig-3a
  *** E2fRE-reporter[CAT] is detectable
    *** cells: KIT225 in BMS "IL2-deprived"
    *** enhanced by: xAkt1(mnr)"CA" [addition]
    *** unaffected by: xAkt1(mnr)"KD" [addition]
    *** source: 9390691-Fig-6a
  *** E2fRE-reporter[CAT] is detectable
    *** cells: KIT225 in BMS "IL2-deprived"
    *** enhanced by: xPik3c?(mnr)"CA" [addition]
    *** unaffected by: xPik3c?(mnr)"KD" [addition]
    *** unaffected by: xPik3r? [addition]
    *** source: 9390691-Fig-5c
  *** E2fRE-reporter[CAT] is detectable
    *** cells: KIT225 in BMS "IL2-deprived"
    *** inhibited by: LY294002 [cotreatment]
    *** source: 9390691-Fig-5b
  *** E2fRE-reporter[CAT] is detectable
    *** cells: KIT225 in BMS "IL2-deprived"
    *** inhibited by: xCdkn1b [addition]
    *** source: 9390691-Fig-3b
  *** E2fRE-reporter[CAT] is detectable
    *** cells: KIT225 in BMS "IL2-deprived"
    *** inhibited by: xPik3r?(mnr)"DN" [addition]
    *** source: 9390691-Fig-5a
  *** E2fRE-reporter[CAT] is detectable
    *** cells: KIT225 in BMS "IL2-deprived" "treated with IL2 for 18 hr"
    *** partially inhibited by: xRb1(mnr)"DN" [addition]
    *** source: 9390691-Fig-2a
  *** E2fRE-reporter[CAT] is increased itpo (xE2f1 + xTfdp1)
    *** cells: C33A in BMS
    *** inhibited by: xRb1 [addition]
    *** unaffected by: xRb1(mnr)"d22" [addition]
    *** source: 7739537-Fig-5
  *** E2fRE-reporter[CAT] is increased itpo (xE2f1 + xTfdp2)
    *** cells: C33A in BMS
    *** inhibited by: xRb1 [addition]
    *** unaffected by: xRb1(mnr)"d22" [addition]
    *** source: 7739537-Fig-5
  *** E2fRE-reporter[CAT] is increased itpo (xE2f2 + xTfdp1)
    *** cells: C33A in BMS
    *** inhibited by: xRb1 [addition]
    *** unaffected by: xRb1(mnr)"d22" [addition]
    *** source: 7739537-Fig-5
  *** E2fRE-reporter[CAT] is increased itpo (xE2f2 + xTfdp2)
    *** cells: C33A in BMS
    *** inhibited by: xRb1 [addition]
    *** unaffected by: xRb1(mnr)"d22" [addition]
    *** source: 7739537-Fig-5
  *** E2fRE-reporter[CAT] is increased itpo (xE2f3 + xTfdp1)
    *** cells: C33A in BMS
    *** inhibited by: xRb1 [addition]
    *** unaffected by: xRb1(mnr)"d22" [addition]
    *** source: 7739537-Fig-5
  *** E2fRE-reporter[CAT] is increased itpo (xE2f3 + xTfdp2)
    *** cells: C33A in BMS
    *** inhibited by: xRb1 [addition]
    *** unaffected by: xRb1(mnr)"d22" [addition]
    *** source: 7739537-Fig-5
  *** E2fRE-reporter[CAT] is increased itpo xAkt1(mnr)"CA"
    *** cells: KIT225 in BMS "IL2-deprived"
    *** source: 9390691-Fig-6c
  *** E2fRE-reporter[CAT] is increased itpo xE2f1
    *** cells: KIT225 in BMS "IL2-deprived"
    *** enhanced by: xTfdp1 [addition]
    *** source: 9390691-Fig-1d
  *** E2fRE-reporter[CAT] is increased itpo xTfdp1
    *** cells: KIT225 in BMS "IL2-deprived"
    *** enhanced by: xE2f1 [addition]
    *** source: 9390691-Fig-1d
  *** E2fRE-reporter[Luc] is decreased itpo xRb1(mnr)
    *** cells: KIT225 in BMS "IL2-deprived"
    *** source: 10373522-Fig-4a
  *** E2fRE-reporter[Luc] is increased itpo xPik3c?(mnr)"CA"
    *** cells: KIT225 in BMS "IL2-deprived"
    *** source: 10373522-Fig-1a
  *** E2fRE-reporter[Luc] is increased itpo xS6k?
    *** cells: KIT225 in BMS "IL2-deprived"
    *** inhibited by: xS6k?(mnr)"KD" [substitution]
    *** source: 10373522-Fig-5a
*** Ecsit--
  *** xEcsit[tAb] copptby[WB] xMekk1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 10465784-Fig-2a
*** Ect2--
  *** xEct2[tAb] snaggedby[WB] rCdc42(G15N)"NucFree"[GST] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-1
  *** xEct2[tAb] snaggedby[WB] rRac1(G15N)"NucFree"[GST] is undetectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-1
  *** xEct2[tAb] snaggedby[WB] rRhoa(G17A)"NucFree"[GST] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-1
  *** xEct2[tAb] snaggedby[WB] rRhog(G15N)"NucFree"[GST] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-1
*** Edd1--
  *** Edd1[Ab] copptby[WB] xErk1[tAb] is detectable
    *** cells: COS1 in BMLS
    *** unaffected by: Egf (10 min) [stim]
    *** source: 12594221-Fig-6b
  *** Edd1[Ab] copptby[WB] xErk2[tAb] is detectable
    *** cells: COS1 in BMLS
    *** unaffected by: Egf (10 min) [stim]
    *** source: 12594221-Fig-6a,6b
  *** Edd1[Ab] copptby[WB] xMek1[tAb] is undetectable
    *** cells: COS1 in BMLS
    *** unaffected by: Egf (10 min) [stim]
    *** source: 12594221-Fig-6b
*** Eea1--
  *** Eea1[Ab] copptby[WB] TgfbR1[Ab] is undetectable
    *** cells: HK2 in BMLS
    *** unaffected by: Hyaluronan (24 hr) [stim]
    *** unaffected by: anti-Cd44 (24 hr) [stim]
    *** unaffected by: PD98059 [addition]
    *** source: 15084590(D)
*** Eef2--
  *** Eef2[Ab]IP phos(T57)[phosAb] is decreased itao Tsc2 [KO]
    *** cells: mEFs in BMLS
    *** source: 15772076-Fig-2d
  *** Eef2[phosAb] phos(T57)[phosAb] is decreased itao Tsc2 [KO]
    *** cells: mEFs in BMLS
    *** reversed by: AA-deprivation [addition]
    *** unaffected by: AA-deprivation + CHX [addition]
    *** source: 15772076-Fig-4c
  *** Eef2[phosAb] phos(T57)[phosAb] is decreased itao Tsc2 [KO]
    *** cells: mEFs in BMLS
    *** source: 15772076-Fig-3c
  *** Eef2[phosAb] phos(T57)[phosAb] is detectable
    *** cells: mEFs in BMLS
    *** reqs: Tsc2 [KO]
    *** source: 15024086-Fig-5b
  *** Eef2[phosAb] phos(T57)[phosAb] is increased itao Pdk1 [KO]
    *** cells: mESCs in BMLS
    *** enhanced by: Rapamycin [addition]
    *** source: 15024086-Fig-5a
  *** Eef2[phosAb] phos(T57)[phosAb] is increased itao Pdpk1 [KO]
    *** cells: mESCs in BMLS
    *** source: 11500364-Fig-1a
  *** Eef2[phosAb] phos(T57)[phosAb] is increased itao Pdpk1 [KO]
    *** cells: mESCs in BMLS
    *** source: 11500364-Fig-1b
  *** Eef2[phosAb] phos(T57)[phosAb] is undetectable
    *** cells: mEFs in BMLS
    *** unaffected by: AA-deprivation [addition]
    *** unaffected by: AA-deprivation + CHX [addition]
    *** source: 15772076-Fig-4c
*** Eef2k--
  *** rEef2k[32P] phos[32P-ATP] is unchanged by rAkt1
    *** cells: none
    *** source: 11500364-Fig-3a
  *** Eef2k[Ab]IP IVKA(Eef2)[32P-ATP] is detectable
    *** cells: KB in BMLS
    *** comment: kinase assay contained Calm
    *** source: 14709557-Fig-6a
  *** Eef2k[Ab]IP IVKA(Eef2)[32P-ATP] is detectable
    *** cells: KB in BMLS
    *** comment: reqs Calm in the kinase assay [omission]
    *** source: 14709557-Fig-6b
  *** Eef2k[Ab]IP IVKA(Eef2)[32P-ATP] is detectable
    *** cells: rAVCs in BMLS
    *** comment: reqs Calm in the kinase assay [omission]
    *** source: 14709557-Fig-6b
  *** Eef2k[Ab]IP IVKA(Eef2)[32P-ATP] is increased itao Pdpk1 [KO]
    *** cells: mESCs in BMLS
    *** source: 11500364-Fig-1c
  *** Eef2k[Ab]IP phos(S77)[phosAb] is increased itao Tsc2 [KO]
    *** cells: mEFs in BMLS
    *** source: 15772076-Fig-2c
  *** Eef2k[Ab]IP phos(S78)[phosAb] is increased itao Pdpk1 [KO]
    *** cells: mESCs in BMLS
    *** inhibited by: Rapamycin [addition]
    *** source: 15024086-Fig-5a
  *** Eef2k[Ab]IP phos(S78)[phosAb] is increased itao Tsc2 [KO]
    *** cells: mEFs in BMLS
    *** source: 15024086-Fig-5b
  *** Eef2k[phosAb] phos(S77)[phosAb] is increased itao Tsc2 [KO]
    *** cells: mEFs in BMLS
    *** inhibited by: AA-deprivation [addition]
    *** unaffected by: AA-deprivation + CHX [addition]
    *** inhibited by: Rapamycin [addition]
    *** source: 15772076-Fig-4b
  *** Eef2k[phosAb] phos(S77)[phosAb] is increased itao Tsc2 [KO]
    *** cells: mEFs in BMLS
    *** source: 15772076-Fig-3d
  *** Eef2k[phosAb] phos(S77)[phosAb] is undetectable
    *** cells: mEFs in BMLS
    *** unaffected by: AA-deprivation [addition]
    *** unaffected by: AA-deprivation + CHX [addition]
    *** source: 15772076-Fig-4b
  *** Eef2k[phosAb] phos(S366)[phosAb] is detectable
    *** cells: HELA in BMS
    *** reqs: Mtor [RNAi]
    *** source: 15268862-Fig-4a
  *** Eef2k[phosAb] phos(S366)[phosAb] is detectable
    *** cells: HELA in BMS
    *** reqs: Raptor [RNAi]
    *** source: 15268862-Fig-4a
  *** Eef2k[phosAb] phos(S366)[phosAb] is increased itao Rictor [RNAi]
    *** cells: HELA in BMS
    *** source: 15268862-Fig-4a
  *** xEef2k[tAb]IP IVKA(Eef2)[32P-ATP] is detectable
    *** cells: KB<xEef2k> in BMLS "treated with Ins (30 min)"
    *** unaffected by: xEef2k(S78A) [substitution]
    *** source: 15024086-Fig-6d
*** Egf--
  *** Egf[125I] internalization[Surface-strip] is decreased itpo xRin1(67-154)"SH2"
    *** cells: CHO<xEgfR> in BMLS
    *** source: 12783862-Fig-6c
  *** Egf[125I] internalization[Surface-strip] is increased itpo xCbl
    *** cells: CHO<xEgfR> in BMS
    *** unaffected by: xCin85 [addition]
    *** source: 11894095-Fig-3c
  *** Egf[125I] internalization[Surface-strip] is increased itpo xRab5a
    *** cells: CHO<xEgfR> in BMLS
    *** source: 12783862-Fig-6c
  *** Egf[125I] internalization[Surface-strip] is increased itpo xRin1
    *** cells: NR6<xEgfR> in BMLS
    *** inhibited by: xRin1(67-154)"SH2" [substitution]
    *** source: 12783862-Fig-6a
  *** Egf[Ab] secretion[ELISA] is decreased itao Adam17 [RNAi]
    *** cells: MDAMB231 in BMS "treated with Cetuximab 30 min"
    *** source: 23720309-Fig-S1c
*** EgfR--
  *** pEgfR(mnr)"cytoplasmic-domain"[32P] phos(Y915)[2D-PPMap] is increased by pSrc
    *** cells: none
    *** source: 7797556-Table-2
  *** pEgfR(mnr)"cytoplasmic-domain"[32P] phos(Y944)[2D-PPMap] is increased by pSrc
    *** cells: none
    *** source: 7797556-Table-2
  *** rEgfR[32P] phos[32P-ATP] is increased by rP38a
    *** cells: none
    *** source: 7535770-Fig-1a
  *** xEgfR[125I] boundby[Xlink] rHbegf[125I] is detectable
    *** cells: NIH3T3<xEgfR> in BMS
    *** source: 9135143-Fig-2
  *** xEgfR[125I] boundby[Xlink] rNrg1[125I] is undetectable
    *** cells: NIH3T3<xEgfR> in BMS
    *** source: 9135143-Fig-2
  *** pEgfR[Ab] cleavage[WB] is increased by rCasp1(mnr)"CA"
    *** cells: none
    *** inhibited by: Z-DEVD-FMK [addition]
    *** inhibited by: Ac-YVAD-CMK [addition]
    *** source: 11226410(D)
  *** pEgfR[Ab] cleavage[WB] is increased by rCasp2(mnr)"CA"
    *** cells: none
    *** source: 11226410(D)
  *** pEgfR[Ab] cleavage[WB] is increased by rCasp3(mnr)"CA"
    *** cells: none
    *** inhibited by: Z-DEVD-FMK [addition]
    *** inhibited by: Ac-YVAD-CMK [addition]
    *** source: 11226410(D)
  *** pEgfR[Ab] cleavage[WB] is increased by rCasp7(mnr)"CA"
    *** cells: none
    *** inhibited by: Z-DEVD-FMK [addition]
    *** partially inhibited by: Ac-YVAD-CMK [addition]
    *** source: 11226410(D)
  *** pEgfR[Ab] cleavage[WB] is unchanged by rCasp4(mnr)"CA"
    *** cells: none
    *** source: 11226410(D)
  *** pEgfR[Ab] cleavage[WB] is unchanged by rCasp6(mnr)"CA"
    *** cells: none
    *** source: 11226410(D)
  *** pEgfR[Ab] cleavage[WB] is unchanged by rCasp8(mnr)"CA"
    *** cells: none
    *** source: 11226410(D)
  *** EgfR[Ab] colocwith[FRET] Itgav[Ab] is undetectable
    *** cells: ECV304 in BMLS
    *** unaffected by: Egf (tnr) [stim]
    *** source: 18844239-Fig-1
  *** EgfR[Ab] copptby[WB] Cdh1[Ab] is detectable
    *** cells: A431 in BMS
    *** unaffected by: Egf (10 min) [stim]
    *** source: 11716761-Fig-3
  *** EgfR[Ab] copptby[WB] Cdh1[Ab] is detectable
    *** cells: HACAT in BMLS
    *** unaffected by: Egf (5 min) [stim]
    *** inhibited by: EGTA [addition]
    *** source: 10969083-Fig-4a
  *** EgfR[Ab] copptby[WB] Cin85[Ab] is detectable
    *** cells: A431 in BMLS
    *** source: 12177062(D)
  *** EgfR[Ab] copptby[WB] Fer[Ab] is detectable
    *** cells: A431 in BMS
    *** unaffected by: Egf (5 min) [stim]
    *** source: 7623846-Fig-1
  *** EgfR[Ab] copptby[WB] Grb2[Ab] is detectable
    *** cells: HER14 in BMS
    *** source: 8386805-Fig-1c
  *** EgfR[Ab] copptby[WB] Jak1[Ab] is detectable
    *** cells: hESKs in BMLS "Egf and BPE starved"
    *** source: 15284024-Fig-5b
  *** xEgfR[Ab] copptby[WB] Jak1[Ab] is detectable
    *** cells: hESKs in BMLS "Egf and BPE starved"
    *** source: 15284024-Fig-5b
  *** EgfR[Ab] copptby[WB] Jak2[Ab] is detectable
    *** cells: A431 in BMLS
    *** unaffected by: Egf (10 min) [stim]
    *** inhibited by: Hbegf (10 min) [stim]
    *** inhibited by: Btc (10 min) [stim]
    *** unaffected by: Nrg1 (10 min) [stim]
    *** source: 10358079-Fig-7b
  *** EgfR[Ab] copptby[WB] Jak2[Ab] is detectable
    *** cells: hESKs in BMLS "Egf and BPE starved"
    *** source: 15284024-Fig-5b
  *** xEgfR[Ab] copptby[WB] Jak2[Ab] is detectable
    *** cells: hESKs in BMLS "Egf and BPE starved"
    *** source: 15284024-Fig-5b
  *** EgfR[Ab] copptby[WB] Tns3[Ab] is detectable
    *** cells: MDAMB468 in BMLS
    *** source: 15140944-Fig-5a
  *** xEgfR[Ab] copptby[WB] xArms[tAb] is undetectable
    *** cells: HEK293<xEgfR><xArms> in BMS
    *** source: 15167895-Fig-2b
  *** EgfR[Ab] copptby[WB] xGrb2[Ab] is detectable
    *** cells: HER14<xGrb2> in BMS
    *** source: 8386805-Fig-1c
  *** EgfR[Ab] copptby[WB] xSh2d3a[tAb] is detectable
    *** cells: COS in BMLS
    *** source: 10187783-Fig-5
  *** xEgfR[Ab] copptby[WB] xSnx6[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 11279102(D)
  *** xEgfR[Ab] copptby[WB] xStat5a[tAb] is detectable
    *** cells: NIH3T3 in BMLS
    *** unaffected by: xStat5a(Y694F) [substitution]
    *** unaffected by: xStat5a(R618L) [substitution]
    *** source: 10358079-Fig-4a
  *** EgfR[Ab] copptby[WB] xTrpv1[Ab] is undetectable
    *** cells: HEK293<xTrpv1> in BMS
    *** source: 11418861-Fig-5a
  *** xEgfR[Ab] infraction(nuclear)[WB] is detectable
    *** cells: CHO<xEgfR> in BMLS
    *** inhibited by: xEgfR(R645A/R646A/R647A) [substitution]
    *** source: 15950906-Fig-5d
  *** xEgfR[Ab] prot-exp[WB] is decreased itpo xPld1
    *** cells: 3Y1<xEgfR> in BMS
    *** source: 11134345-Fig-6b
  *** xEgfR[Ab] prot-exp[WB] is decreased itpo xPld2
    *** cells: 3Y1<xEgfR> in BMS
    *** source: 11134345-Fig-6b
  *** xEgfR[Ab] prot-exp[WB] is increased itpo xPld1(K898R)"CIA"
    *** cells: 3Y1<xEgfR> in BMS
    *** source: 11134345-Fig-6b
  *** xEgfR[Ab] prot-exp[WB] is increased itpo xPld2(K758R)"CIA"
    *** cells: 3Y1<xEgfR> in BMS
    *** source: 11134345-Fig-6b
  *** xEgfR[Ab] snaggedby[WB] rPtpn6(mnr)"SH2"[GST] is detectable
    *** cells: HEK293<xEgfR> in BMS "treated with Egf for 5 min"
    *** unaffected by: xEgfR(Y954F) [substitution]
    *** unaffected by: xEgfR(Y1068F) [substitution]
    *** unaffected by: xEgfR(Y1148F) [substitution]
    *** partially inhibited by: xEgfR(Y1173F) [substitution]
    *** partially inhibited by: xEgfR(Y954F/Y1173F) [substitution]
    *** source: 9733788-Fig-3a
  *** xEgfR[Ab] snaggedby[WB] rPtpn6[GST] is detectable
    *** cells: HEK293<xEgfR> in BMS "treated with Egf for 5 min"
    *** inhibited by: rPtpn6(R32K) [substitution]
    *** inhibited by: rPtpn6(R138K) [substitution]
    *** source: 9733788-Fig-4b
  *** EgfR[Ab]IP surface-exp[biotin-labeling] is increased itpo xArhGef7
    *** cells: NIH3T3<xSrc(mnr)"vSrc"> in BMLS
    *** inhibited by: xArhGef7(Y619F) [substitution]
    *** source: 16892055-Fig-4d
  *** EgfR[Ab]IP ubiq[UbAb] is increased itpo xCbl
    *** cells: HEK293 in BMLS
    *** source: 10531381(D)
  *** EgfR[Ab]IP ubiq[UbAb] is increased itpo xUbe2l3
    *** cells: HEK293 in BMLS
    *** inhibited by: xCbl(del(366-382))"DN" [addition]
    *** source: 10531381(D)
  *** EgfR[Ab]IP Yphos[pYAb] is decreased itao P38a [RNAi]
    *** cells: T42 in BMLS
    *** source: 20188673-Fig-7g
  *** EgfR[Ab]IP Yphos[pYAb] is increased irt anti-Itgav-adherence (60 min)
    *** cells: ECV304 in BMLS
    *** source: 18844239-Fig-2c
  *** EgfR[Ab]IP Yphos[pYAb] is increased irt anti-Itgb1-adherence (60 min)
    *** cells: ECV304 in BMLS
    *** source: 18844239-Fig-2c
  *** xEgfR[phosAb] phos(S1070/S1071)[phosAb] is detectable
    *** cells: HEK293<xEgfR> in BMS
    *** inhibited by: xEgfR(mnr)"KD" [substitution]
    *** source: 19687304-Fig-2d
  *** xEgfR[phosAb] phos(S1070/S1071)[phosAb] is increased itpo (xTak1 + xTab1 + xTab2)
    *** cells: HEK293<xEgfR> in BMS
    *** inhibited by: xEgfR(S1070A/S1071A) [substitution]
    *** source: 19687304-Fig-2f
  *** xEgfR[phosAb] phos(S1070/S1071)[phosAb] is increased itpo (xTak1 + xTab1 + xTab2)
    *** cells: HEK293<xEgfR> in BMS
    *** source: 19687304-Fig-2d
  *** xEgfR[phosAb] phos(S1070/S1071)[phosAb] is increased itpo (xTak1 + xTab1 + xTab2)
    *** cells: HEK293<xEgfR> in BMS
    *** unaffected by: xEgfR(T693A) [substitution]
    *** source: 19687304-Fig-2e
  *** xEgfR[phosAb] phos(T693)[phosAb] is detectable
    *** cells: HEK293<xEgfR> in BMS
    *** inhibited by: xEgfR(mnr)"KD" [substitution]
    *** source: 19687304-Fig-2d
  *** xEgfR[phosAb] phos(T693)[phosAb] is increased itpo (xTak1 + xTab1 + xTab2)
    *** cells: HEK293<xEgfR> in BMS
    *** inhibited by: xEgfR(T693A) [substitution]
    *** source: 19687304-Fig-2e
  *** xEgfR[phosAb] phos(T693)[phosAb] is increased itpo (xTak1 + xTab1 + xTab2)
    *** cells: HEK293<xEgfR> in BMS
    *** source: 19687304-Fig-2d
  *** xEgfR[phosAb] phos(T693)[phosAb] is increased itpo (xTak1 + xTab1 + xTab2)
    *** cells: HEK293<xEgfR> in BMS
    *** unaffected by: xEgfR(S1070A/S1071A) [substitution]
    *** source: 19687304-Fig-2f
  *** xEgfR[phosAb] phos(Y869)[phosAb] is decreased itpo (xTak1 + xTab1 + xTab2)
    *** cells: HEK293<xEgfR> in BMS
    *** source: 19687304-Fig-2b
  *** xEgfR[phosAb] phos(Y1016)[phosAb] is decreased itpo (xTak1 + xTab1 + xTab2)
    *** cells: HEK293<xEgfR> in BMS
    *** source: 19687304-Fig-2b
  *** xEgfR[phosAb] phos(Y1069)[phosAb] is decreased itpo (xTak1 + xTab1 + xTab2)
    *** cells: HEK293<xEgfR> in BMS
    *** source: 19687304-Fig-2b
  *** EgfR[phosAb] phos(Y1069)[phosAb] is detectable
    *** cells: A431 in BMS
    *** partially reqs: Stat1 [RNAi]
    *** does not req: Stat3 [RNAi]
    *** source: 17646016-Fig-4
  *** xEgfR[phosAb] phos(Y1092)[phosAb] is decreased itpo (xTak1 + xTab1 + xTab2)
    *** cells: HEK293<xEgfR> in BMS
    *** source: 19687304-Fig-2b
  *** xEgfR[phosAb] phos(Y1197)[phosAb] is decreased itpo (xTak1 + xTab1 + xTab2)
    *** cells: HEK293<xEgfR> in BMS
    *** source: 19687304-Fig-2b
  *** Egr1-gene mRNA[RTPCR] is detectable
    *** cells: mSpBCs in BMS "treated with anti-Cd40 (24 hr)"
    *** partially inhibited by: kMekk1(1-1188)"del-kinase-domain" [addition]
    *** source: 17143273-Fig-6c
  *** Egr1-gene mRNA[RTPCR] is increased itao Hdac1 [RNAi]
    *** cells: HELA in BMS
    *** source: 14992729-Fig-4a
  *** Egr1-gene mRNA[RTPCR] is increased itao Hdac2 [RNAi]
    *** cells: HELA in BMS
    *** source: 14992729-Fig-4a
  *** Egr1-gene mRNA[RTPCR] is unchanged itao Hdac3 [RNAi]
    *** cells: HELA in BMS
    *** source: 14992729-Fig-4a
  *** Egr1-gene promo-reporter[Luc] is decreased itao Hdac2 [RNAi]
    *** cells: HELA in BMS
    *** source: 14992729-Fig-4b
  *** Egr1-gene promo-reporter[Luc] is increased itao Elk1 [RNAi]
    *** cells: HELA in BMS
    *** source: 14992729-Fig-4d
  *** Egr1-gene promo-reporter[Luc] is increased itao Hdac1 [RNAi]
    *** cells: HELA in BMS
    *** does not req: Elk1 [RNAi]
    *** source: 14992729-Fig-4d
  *** Egr1-gene promo-reporter[Luc] is increased itao Hdac1 [RNAi]
    *** cells: HELA in BMS
    *** source: 14992729-Fig-4b
  *** Egr1-gene promo-reporter[Luc] is increased itao Hdac2 [RNAi]
    *** cells: HELA in BMS
    *** does not req: Elk1 [RNAi]
    *** source: 14992729-Fig-4d
  *** Egr1-gene promo-reporter[Luc] is increased itao Hdac2 [RNAi]
    *** cells: HELA in BMS
    *** source: 14992729-Fig-4b
  *** Egr1-gene promo-reporter[Luc] is increased itpo xElk1
    *** cells: HACAT in BMS
    *** inhibited by: xJnk1(T183A/Y185F) [addition]
    *** inhibited by: xErk2(K52R) [addition]
    *** source: 18675783-Fig-4c
  *** Egr1-gene promo-reporter[Luc] is increased itpo xElk1
    *** cells: mESCs<Med23~null><xMekk1(mnr)"CA"> in BMS
    *** reqs: xMekk1(mnr)"CA" [omission]
    *** source: 19417246-Fig-S6a
  *** Egr1-gene promo-reporter[Luc] is increased itpo xElk3
    *** cells: mESCs<Med23~null><xMekk1(mnr)"CA"> in BMS
    *** reqs: xMekk1(mnr)"CA" [omission]
    *** source: 19417246-Fig-S6a
  *** Egr1-gene promo-reporter[Luc] is increased itpo xElk4
    *** cells: mESCs<Med23~null><xMekk1(mnr)"CA"> in BMS
    *** reqs: xMekk1(mnr)"CA" [omission]
    *** source: 19417246-Fig-S6a
  *** Egr1-gene promo-reporter[Luc] is increased itpo xPias2a
    *** cells: HEK293 in BMLS
    *** inhibited by: xPias2a(del(467-487)) [substitution]
    *** source: 15920481-Fig-6f
*** Egr1-gene--
  *** Egr1[Ab] boundto(Tp53-gene)[ChIP] is detectable
    *** cells: DU145 in BMS
    *** source: 15958557-Fig-5
  *** Egr1[Ab] boundto(Tp53-gene)[ChIP] is detectable
    *** cells: mEFs in BMS
    *** reqs: Egr1 [KO]
    *** source: 15958557-Fig-5
  *** Egr1[Ab] oligo-binding[EMSA] is detectable
    *** cells: mEFs in BMS
    *** oligo: "Egr1-consensus" 5-CGCCCCCGC-3
    *** reqs: Egr1 [KO]
    *** source: 15958557-Fig-4a
  *** Egr1[Ab] oligo-binding[EMSA] is detectable
    *** cells: mEFs in BMS
    *** oligo: "Tp53!Mouse" 5-AAACCGTGGGGTTTGGGGGTGGGGCAGTG-3
    *** reqs: Egr1 [KO]
    *** source: 15958557-Fig-4a
  *** Egr1[Ab] oligo-binding[EMSA] is detectable
    *** cells: mEFs in BMS
    *** oligo: "Tp53!Mouse" 5-TTTCCCTTTCTCCCCCGCCCTCCCTTCA-3
    *** reqs: Egr1 [KO]
    *** source: 15958557-Fig-4a
  *** Egr1[Ab] prot-exp[WB] is detectable
    *** cells: ECV304 in BMLS "plated on anti-Itgav"
    *** inhibited by: xAkt1(mnr)"DN" [addition]
    *** source: 18844239-Fig-4b
  *** Egr1[Ab] prot-exp[WB] is detectable
    *** cells: ECV304 in BMLS "plated on Fn1"
    *** reqs: Akt1 [RNAi]
    *** source: 18844239-Fig-4b
  *** Egr1[Ab] prot-exp[WB] is increased irt anti-Itgav-adherence (60 min)
    *** cells: ECV304 in BMLS
    *** unaffected by: Egf (tnr) [stim]
    *** source: 18844239-Fig-2c
  *** Egr1[Ab] prot-exp[WB] is increased irt anti-Itgb1-adherence (60 min)
    *** cells: ECV304 in BMLS
    *** unaffected by: Egf (tnr) [stim]
    *** source: 18844239-Fig-2c
  *** Egr2-gene mRNA[RTPCR] is detectable
    *** cells: mEFs in BMS
    *** reqs: Egr1 [KO]
    *** source: 15958557-Fig-1
  *** Egr3-gene mRNA[RTPCR] is decreased itpo xEgr2
    *** cells: NEURO2A in BMS
    *** source: 11111043-Fig-5a
  *** Egr3-gene mRNA[RTPCR] is increased itpo xEgr1
    *** cells: C2C12 in BMS
    *** enhanced by: xEgr1(mnr)"Nab-insensitive" [substitution]
    *** source: 11111043-Fig-5a
  *** Egr3-gene mRNA[RTPCR] is increased itpo xEgr2
    *** cells: C2C12 in BMS
    *** source: 11111043-Fig-5a
  *** Egr3-gene mRNA[RTPCR] is unchanged itpo xEgr1
    *** cells: NEURO2A in BMS
    *** unaffected by: xEgr1(mnr)"Nab-insensitive" [substitution]
    *** source: 11111043-Fig-5a
  *** EgrRE-reporter[Luc] is detectable
    *** cells: CHO<xEgr1> in BMS
    *** inhibited by: xNab2 [addition]
    *** enhanced by: xEgr1(mnr)"repressive-domain" [addition]
    *** source: 11111043-Fig-3a
  *** EgrRE-reporter[Luc] is detectable
    *** cells: CHO<xEgr1> in BMS
    *** inhibited by: xNab2 [addition]
    *** source: 11111043-Fig-3b
  *** EgrRE-reporter[Luc] is increased itpo xEgr1
    *** cells: CHO in BMS
    *** enhanced by: xEgr1(mnr)"Nab-insensitive" [substitution]
    *** source: 11111043-Fig-2b
  *** EgrRE-reporter[Luc] is increased itpo xEgr2
    *** cells: CHO in BMS
    *** source: 11111043-Fig-2b
  *** Eif3[Ab] copptby[WB] xEif4b[tAb] is detectable
    *** cells: HELA<xEif4b> in BMLS
    *** inhibited by: xEif4b(S442A) [substitution]
    *** enhanced by: xEif4b(S442E) [substitution]
    *** source: 16763566-Fig-6b
  *** Eif3[Ab] copptby[WB] xEif4b[tAb] is detectable
    *** cells: HELA<xEif4b><xRsk1> in BMLS
    *** inhibited by: xRsk1(mnr)"KD" [substitution]
    *** enhanced by: xRsk1(myr)"CA" [substitution]
    *** source: 16763566-Fig-6a
*** Eif3a--
  *** Eif3a[Ab] copptby[WB] Eif3b[Ab] is detectable
    *** cells: 3T3L1 in BMLS "AminoAcid deprived" "differentiated into adipocytes"
    *** unaffected by: Rapamycin [addition]
    *** unaffected by: Ins (15 min) [stim]
    *** source: 16541103-Fig-2c
  *** xEif3f[tAb] copptby[WB] xMtor[tAb] is detectable
    *** cells: HEK293T in BMLS "AminoAcid deprived"
    *** source: 16541103-Fig-1c
  *** Eif3i[Ab] copptby[WB] Eif3b[Ab] is detectable
    *** cells: 3T3L1 in BMLS "AminoAcid deprived" "differentiated into adipocytes"
    *** unaffected by: Rapamycin [addition]
    *** unaffected by: Ins (15 min) [stim]
    *** source: 16541103-Fig-2c
  *** Eif3j[Ab] copptby[WB] Eif3b[Ab] is detectable
    *** cells: 3T3L1 in BMLS "AminoAcid deprived" "differentiated into adipocytes"
    *** unaffected by: Ins (15 min) [stim]
    *** unaffected by: Rapamycin [addition]
    *** source: 16541103-Fig-S1
*** Eif4a1--
  *** Eif4a1[Ab] copptby[WB] Eif4g1[Ab] is detectable
    *** cells: 3T3L1 in BMLS "AminoAcid deprived" "differentiated into adipocytes"
    *** unaffected by: Ins (15 min) [stim]
    *** source: 16541103-Fig-S1
  *** Eif4a1[Ab] copptby[WB] Eif4g1[Ab] is detectable
    *** cells: 3T3L1 in BMLS "AminoAcid deprived" "differentiated into adipocytes"
    *** unaffected by: Rapamycin [addition]
    *** unaffected by: Ins (15 min) [stim]
    *** source: 16541103-Fig-2c
*** Eif4b--
  *** xEif4b[tAb] copptby[WB] Eif3b[Ab] is detectable
    *** cells: HEK293T<xEif4b> in BMLS "AminoAcid deprived"
    *** unaffected by: xEif4g1 [addition]
    *** unaffected by: xS6k1 [addition]
    *** source: 16541103-Fig-6d
  *** xEif4b[tAb]IP phos(S422)[phosAb] is detectable
    *** cells: HELA<xEif4b><xRsk1> in BMLS
    *** inhibited by: xRsk1(mnr)"KD" [substitution]
    *** enhanced by: xRsk1(myr)"CA" [substitution]
    *** source: 16763566-Fig-6a
  *** xEif4b[tAb]IP phos(S422)[phosAb] is increased itpo xRsk1(myr)"CA"
    *** cells: HELA<xEif4b> in BMLS
    *** source: 16763566-Fig-4b
  *** xEif4b[tAb]IP phos(S422)[phosAb] is increased itpo xRsk1(myr)"CA"
    *** cells: HELA<xEif4b> in BMLS
    *** source: 16763566-Fig-4c
*** Eif4e--
  *** rEif4e[32P] phos[32P-ATP] is increased by rMnk2b{act}
    *** cells: none
    *** comment: rMnk2b was activated by phos with rP38a{act}
    *** inhibited by: rEif4e(S209A) [substitution]
    *** source: 12897141-Fig-3b
  *** rEif4e[32P] phos[32P-ATP] is unchanged by xMnk2b[tAb]IP
    *** cells: none
    *** IPfrom: HEK293<xMnk2b> in BMS
    *** source: 12897141-Fig-2d
  *** Eif4e[m7GTP]IP phos[WBMS] is increased itpo xMnk2b
    *** cells: HEK293 in BMS
    *** source: 12897141-Fig-2e
  *** xEif4e[phosAb] phos(S209)[phosAb] is increased itpo xMek1(mnr)"CA"
    *** cells: HEK293 in BMLS
    *** source: 11463832-Fig-2d
  *** xEif4e[phosAb] phos(S209)[phosAb] is increased itpo xMek1(mnr)"CA"
    *** cells: HEK293<xMnk1> in BMLS
    *** inhibited by: xMek1(mnr)"DN" [substitution]
    *** source: 11463832-Fig-2d
  *** xEif4e[phosAb] phos(S209)[phosAb] is increased itpo xMek5(mnr)"CA"
    *** cells: HEK293<xMnk1> in BMLS
    *** source: 11463832-Fig-2c
  *** xEif4e[phosAb] phos(S209)[phosAb] is increased itpo xMek5(mnr)"DN"
    *** cells: HEK293<xMnk1> in BMLS
    *** source: 11463832-Fig-2c
  *** xEif4e[phosAb] phos(S209)[phosAb] is increased itpo xMkk3(mnr)"CA"
    *** cells: HEK293 in BMLS
    *** source: 11463832-Fig-2d
  *** xEif4e[phosAb] phos(S209)[phosAb] is increased itpo xMkk3(mnr)"CA"
    *** cells: HEK293<xMnk1> in BMLS
    *** inhibited by: xMkk3(mnr)"DN" [substitution]
    *** source: 11463832-Fig-2c
  *** xEif4e[phosAb] phos(S209)[phosAb] is increased itpo xMkk6
    *** cells: HEK293 in BMLS
    *** source: 11463832-Fig-2d
  *** xEif4e[phosAb] phos(S209)[phosAb] is increased itpo xMkk6
    *** cells: HEK293<xMnk1> in BMLS
    *** inhibited by: xMkk6(mnr)"DN" [substitution]
    *** source: 11463832-Fig-2c
  *** xEif4e[phosAb] phos(S209)[phosAb] is increased itpo xMkk7(mnr)"CA"
    *** cells: HEK293<xMnk1> in BMLS
    *** source: 11463832-Fig-2c
  *** xEif4e[phosAb] phos(S209)[phosAb] is increased itpo xMkk7(mnr)"DN"
    *** cells: HEK293<xMnk1> in BMLS
    *** source: 11463832-Fig-2c
  *** xEif4e[phosAb] phos(S209)[phosAb] is unchanged itpo xMek5(mnr)"CA"
    *** cells: HEK293 in BMLS
    *** source: 11463832-Fig-2d
  *** xEif4e[phosAb] phos(S209)[phosAb] is unchanged itpo xMkk7(mnr)"CA"
    *** cells: HEK293 in BMLS
    *** source: 11463832-Fig-2d
*** Eif4ebp1--
  *** xEif4ebp1(S65A)[phosAb] phos(S65/S101)[phosAb] is detectable
    *** cells: HEK293<xEif4ebp1(S65A)> in BMLS
    *** unaffected by: Ins (30 min) [stim]
    *** unaffected by: Serum (30 min) [stim]
    *** unaffected by: LY294002 (30 min) [stim]
    *** unaffected by: Rapamycin (30 min) [stim]
    *** unaffected by: SB202190 (30 min) [stim]
    *** unaffected by: PD184352 (30 min) [stim]
    *** source: 12588975-Fig-2a
  *** Eif4ebp1[Ab] phos[WBMS] is detectable
    *** cells: mESCs in BMLS
    *** does not req: Pdpk1 [KO]
    *** source: 11500364-Fig-2a
  *** Eif4ebp1[Ab] phos[WBMS] is increased itao Pdk1 [KO]
    *** cells: mESCs in BMLS
    *** inhibited by: Rapamycin [addition]
    *** source: 15024086-Fig-5a
  *** Eif4ebp1[Ab] snaggedby[WB] capped-mRNA[m7GTP] is decreased itao Tsc2 [KO]
    *** cells: mEFs in BMLS
    *** source: 15772076-Fig-3e
  *** Eif4ebp1[Ab] snaggedby[WB] capped-mRNA[m7GTP] is decreased itao Tsc2 [KO]
    *** cells: mEFs in BMLS
    *** unaffected by: AA-deprivation [addition]
    *** unaffected by: AA-deprivation + CHX [addition]
    *** unaffected by: Rapamycin [addition]
    *** source: 15772076-Fig-4e
  *** Eif4ebp1[Ab] snaggedby[WB] capped-mRNA[m7GTP] is detectable
    *** cells: mEFs in BMLS
    *** unaffected by: AA-deprivation [addition]
    *** unaffected by: AA-deprivation + CHX [addition]
    *** source: 15772076-Fig-4e
  *** Eif4ebp1[Ab] snaggedby[WB] capped-mRNA[m7GTP] is detectable
    *** cells: mEFs<Tp53~null> in BMS
    *** reqs: Tsc2 [KO]
    *** source: 15545625-Fig-1c
  *** Eif4ebp1[Ab] snaggedby[WB] capped-mRNA[m7GTP] is increased itpo xRaptor
    *** cells: HEK293T in BMS
    *** inhibited by: xRaptor(Y194A/D195A/C196A) [substitution]
    *** source: 12150925-Fig-6f
  *** Eif4ebp1[phosAb] phos(S64)[phosAb] is detectable
    *** cells: mESCs in BMLS
    *** does not req: Pdpk1 [KO]
    *** source: 11500364-Fig-2c
  *** Eif4ebp1[phosAb] phos(S64)[phosAb] is increased itao Tsc2 [KO]
    *** cells: mEFs in BMLS
    *** partially inhibited by: AA-deprivation [addition]
    *** partially inhibited by: AA-deprivation + CHX [addition]
    *** inhibited by: Rapamycin [addition]
    *** source: 15772076-Fig-4d
  *** Eif4ebp1[phosAb] phos(S64)[phosAb] is increased itao Tsc2 [KO]
    *** cells: mEFs in BMLS
    *** source: 15772076-Fig-2b
  *** Eif4ebp1[phosAb] phos(S64)[phosAb] is increased itao Tsc2 [KO]
    *** cells: mEFs in BMLS
    *** source: 15772076-Fig-3b
  *** Eif4ebp1[phosAb] phos(S64)[phosAb] is undetectable
    *** cells: mEFs in BMLS
    *** inhibited by: AA-deprivation [addition]
    *** inhibited by: AA-deprivation + CHX [addition]
    *** source: 15772076-Fig-4d
  *** Eif4ebp1[phosAb] phos(S65)[phosAb] is decreased itpo xAmpk(mnr)"CA"
    *** cells: RAT1A in BMS
    *** source: 16027121-Fig-4a
  *** xEif4ebp1[phosAb] phos(S65)[phosAb] is decreased itpo xBnip3
    *** cells: HEK293<xEif4ebp1> in BMS
    *** source: 17928295-Fig-2b
  *** xEif4ebp1[phosAb] phos(S65)[phosAb] is decreased itpo xRagA(T21N)
    *** cells: HEK293<xEif4ebp1> in BMS
    *** unaffected by: xRagC(S75N) [addition]
    *** source: 18604198-Fig-2c
  *** Eif4ebp1[phosAb] phos(S65)[phosAb] is decreased itpo xTsc1
    *** cells: MDAMB453 in BMLS
    *** unaffected by: xTsc1(mnr)"SSAA" [substitution]
    *** reversed by: xTsc1(mnr)"SSAA" [substitution]
    *** source: 18949383-Fig-1b
  *** Eif4ebp1[phosAb] phos(S65)[phosAb] is decreased itpo xTsc2
    *** cells: EEF8<Tsc2~null> in BMS
    *** unaffected by: xTsc2(S1271A/S1387A) [substitution]
    *** source: 14651849-Fig-6c
  *** Eif4ebp1[phosAb] phos(S65)[phosAb] is detectable
    *** cells: EEF4 in BMS
    *** unaffected by: Rottlerin [addition]
    *** partially inhibited by: FCCP [addition]
    *** partially inhibited by: NaN3 [addition]
    *** partially inhibited by: Oligomycin [addition]
    *** partially inhibited by: Rotenone [addition]
    *** source: 14651849-Fig-3d
  *** Eif4ebp1[phosAb] phos(S65)[phosAb] is detectable
    *** cells: EEF8<Tsc2~null> in BMS
    *** unaffected by: Rottlerin [addition]
    *** partially inhibited by: FCCP [addition]
    *** partially inhibited by: NaN3 [addition]
    *** partially inhibited by: Oligomycin [addition]
    *** partially inhibited by: Rotenone [addition]
    *** source: 14651849-Fig-3d
  *** Eif4ebp1[phosAb] phos(S65)[phosAb] is detectable
    *** cells: HELA in BMLS
    *** partially reqs: Vps34 [RNAi]
    *** source: 16049009-Fig-5c
  *** Eif4ebp1[phosAb] phos(S65)[phosAb] is detectable
    *** cells: LEF<Tsc2~null><xTsc2> in BMS
    *** enhanced by: xTsc2(S1371A/S1375A/S1337A/S1383A)"DN" [substitution]
    *** comment: aa numbers converted to Uniprot human canonical sequence
    *** source: 16959574-Fig-S7b
  *** xEif4ebp1[phosAb] phos(S65)[phosAb] is detectable-but unchanged itpo xRagA
    *** cells: HEK293<xEif4ebp1> in BMS
    *** unaffected by: xRagC [addition]
    *** source: 18604198-Fig-2c
  *** xEif4ebp1[phosAb] phos(S65)[phosAb] is detectable-but unchanged itpo xRagA(Q66L)
    *** cells: HEK293<xEif4ebp1> in BMS
    *** unaffected by: xRagA(Q120L) [addition]
    *** source: 18604198-Fig-2c
  *** xEif4ebp1[phosAb] phos(S65)[phosAb] is detectable-but unchanged itpo xRagC
    *** cells: HEK293<xEif4ebp1> in BMS
    *** unaffected by: xRagA [addition]
    *** source: 18604198-Fig-2c
  *** xEif4ebp1[phosAb] phos(S65)[phosAb] is detectable-but unchanged itpo xRagC(Q120L)
    *** cells: HEK293<xEif4ebp1> in BMS
    *** unaffected by: xRagA(Q120L) [addition]
    *** source: 18604198-Fig-2c
  *** xEif4ebp1[phosAb] phos(S65)[phosAb] is detectable-but unchanged itpo xRagC(S75N)
    *** cells: HEK293<xEif4ebp1> in BMS
    *** inhibited by: xRagA(T21N) [addition]
    *** source: 18604198-Fig-2c
  *** rEif4ebp1[phosAb] phos(S65)[phosAb] is increased by rMsk1{act}
    *** cells: none
    *** source: 11777913-Fig-6
  *** rEif4ebp1[phosAb] phos(S65)[phosAb] is increased by rP38a{act}
    *** cells: none
    *** source: 11777913-Fig-6
  *** Eif4ebp1[phosAb] phos(S65)[phosAb] is increased itpo xAkt1(myr)"CA"
    *** cells: RAT1A in BMS
    *** unaffected by: Serum-deprivation [pretreatment]
    *** source: 16027121-Fig-2f
  *** xEif4ebp1[phosAb] phos(S65)[phosAb] is increased itpo xRheb
    *** cells: HEK293<xEif4ebp1> in BSS
    *** partially inhibited by: xBnip3 [addition]
    *** source: 17928295-Fig-3b
  *** xEif4ebp1[phosAb] phos(S65)[phosAb] is increased itpo xRheb
    *** cells: HEK293E<xEif4ebp1> in BMLS
    *** inhibited by: Rapamycin [addition]
    *** source: 12906785-Fig-2a
  *** xEif4ebp1[phosAb] phos(S65)[phosAb] is increased itpo xRheb
    *** cells: HEK293E<xEif4ebp1> in BMLS
    *** inhibited by: Wortmannin [addition]
    *** source: 12906785-Fig-2a
  *** xEif4ebp1[phosAb] phos(S65)[phosAb] is increased itpo xRheb
    *** cells: HEK293T<xEif4ebp1> in BMS
    *** unaffected by: xRheb(I39K) [substitution]
    *** unaffected by: xRheb(D60I) [substitution]
    *** unaffected by: xRheb(C181S) [substitution]
    *** source: 15854902-Fig-S2
  *** Eif4ebp1[phosAb] phos(S65)[phosAb] is increased itpo xTsc2
    *** cells: LEF<Tsc2~null> in BMS
    *** inhibited by: xTsc2(S1371A/S1375A/S1337A/S1383A) [substitution]
    *** comment: aa numbers converted to Uniprot human canonical sequence
    *** source: 16959574-Fig-7f
  *** Eif4ebp1[phosAb] phos(S65)[phosAb] is unchanged itao Tsc2 [KO]
    *** cells: mEFs in BMS
    *** unaffected by: xAkt1(myr)"CA" [addition]
    *** source: 16027121-Fig-6c
  *** Eif4ebp1[phosAb] phos(S65)[phosAb] is unchanged itpo xAkt1(myr)"CA"
    *** cells: mEFs<Tsc2~null> in BMS
    *** source: 16027121-Fig-6c
  *** xEif4ebp1[phosAb] phos(S65)[phosAb] is unchanged itpo xBnip3l
    *** cells: HEK293<xEif4ebp1> in BMS
    *** source: 17928295-Fig-2b
  *** xEif4ebp1[phosAb] phos(S65/S101)[phosAb] is detectable
    *** cells: HEK293<xEif4ebp1> in BMLS
    *** enhanced by: Ins (30 min) [stim]
    *** unaffected by: Rapamycin (30 min) [stim]
    *** source: 12588975-Fig-4d
  *** xEif4ebp1[phosAb] phos(S65/S101)[phosAb] is detectable
    *** cells: HEK293<xEif4ebp1> in BMLS
    *** inhibited by: xEif4ebp1(1-112) [substitution]
    *** source: 12588975-Fig-4d
  *** xEif4ebp1[phosAb] phos(S65/S101)[phosAb] is detectable
    *** cells: HEK293<xEif4ebp1> in BMLS
    *** inhibited by: xEif4ebp1(S101A) [substitution]
    *** inhibited by: xEif4ebp1(S101E) [substitution]
    *** inhibited by: xEif4ebp1(S101D) [substitution]
    *** source: 12588975-Fig-2b
  *** Eif4ebp1[phosAb] phos(T36/T45)[phosAb] is detectable
    *** cells: HEK293T<xMtor><xRheb> in BMLS
    *** inhibited by: AA-deprivation (1 hr) [stim]
    *** inhibited by: H2O2 (30 min) [stim]
    *** inhibited by: Sorbitol (30 min) [stim]
    *** unaffected by: Arsenite (30 min) [stim]
    *** source: 15772076-Fig-6a
  *** Eif4ebp1[phosAb] phos(T36/T45)[phosAb] is increased itao Tsc2 [KO]
    *** cells: mEFs in BMLS
    *** partially inhibited by: AA-deprivation [addition]
    *** partially inhibited by: AA-deprivation + CHX [addition]
    *** inhibited by: Rapamycin [addition]
    *** source: 15772076-Fig-4d
  *** Eif4ebp1[phosAb] phos(T36/T45)[phosAb] is unchanged itao Tsc2 [KO]
    *** cells: mEFs in BMLS
    *** source: 15772076-Fig-3b
  *** Eif4ebp1[phosAb] phos(T36/T45)[phosAb] is undetectable
    *** cells: mEFs in BMLS
    *** inhibited by: AA-deprivation [addition]
    *** inhibited by: AA-deprivation + CHX [addition]
    *** source: 15772076-Fig-4d
  *** rEif4ebp1[phosAb] phos(T37)[phosAb] is increased by rMsk1{act}
    *** cells: none
    *** source: 11777913-Fig-6
  *** rEif4ebp1[phosAb] phos(T37)[phosAb] is increased by rP38a{act}
    *** cells: none
    *** source: 11777913-Fig-6
  *** xEif4ebp1[phosAb] phos(T37/T36)[phosAb] is increased itpo xRheb
    *** cells: HEK293T<xEif4ebp1> in BMS
    *** unaffected by: xRheb(I39K) [substitution]
    *** unaffected by: xRheb(D60I) [substitution]
    *** unaffected by: xRheb(C181S) [substitution]
    *** source: 15854902-Fig-S2
  *** xEif4ebp1[phosAb] phos(T37/T46)[phosAb] is detectable
    *** cells: HEK293<xEif4ebp1> in BMLS
    *** enhanced by: Ins (30 min) [stim]
    *** unaffected by: Rapamycin (30 min) [stim]
    *** source: 12588975-Fig-4c
  *** xEif4ebp1[phosAb] phos(T37/T46)[phosAb] is detectable
    *** cells: HEK293<xEif4ebp1> in BMLS
    *** inhibited by: xEif4ebp1(1-112) [substitution]
    *** source: 12588975-Fig-4c
  *** Eif4ebp1[phosAb] phos(T37/T46)[phosAb] is detectable
    *** cells: mESCs in BMLS
    *** does not req: Pdpk1 [KO]
    *** source: 11500364-Fig-2c
  *** Eif4ebp1[phosAb] phos(T37/T46)[phosAb] is increased itao Tsc2 [KO]
    *** cells: mEFs in BMLS
    *** source: 15772076-Fig-2b
  *** Eif4ebp1[phosAb] phos(T37/T46)[phosAb] is increased itpo xRheb
    *** cells: HEK293 in BMS
    *** source: 15772076-Fig-1a
  *** rEif4ebp1[phosAb] phos(T46)[phosAb] is increased by rMsk1{act}
    *** cells: none
    *** source: 11777913-Fig-6
  *** rEif4ebp1[phosAb] phos(T46)[phosAb] is increased by rP38a{act}
    *** cells: none
    *** source: 11777913-Fig-6
  *** Eif4ebp1[phosAb] phos(T69)[phosAb] is detectable-but unchanged itao Tsc2 [KO]
    *** cells: mEFs in BMLS
    *** source: 15772076-Fig-2b
  *** Eif4ebp1[phosAb] phos(T70)[phosAb] is decreased itpo xDdit4
    *** cells: U2OS in BMS
    *** unaffected by: xDdit4(del(96-156))"dC" [substitution]
    *** source: 15988001-Fig-5a
  *** xEif4ebp1[phosAb] phos(T70)[phosAb] is detectable
    *** cells: HEK293<xEif4ebp1> in BMLS
    *** inhibited by: xEif4ebp1(1-112) [substitution]
    *** source: 12588975-Fig-4d
  *** xEif4ebp1[phosAb] phos(T70)[phosAb] is increased itpo xRheb
    *** cells: HEK293<xEif4ebp1> in BMS
    *** source: 12820960-Fig-3b
  *** xEif4ebp1[phosAb] phos(T70)[phosAb] is increased itpo xRheb
    *** cells: HEK293T<xEif4ebp1> in BMS
    *** unaffected by: xRheb(I39K) [substitution]
    *** unaffected by: xRheb(D60I) [substitution]
    *** unaffected by: xRheb(C181S) [substitution]
    *** source: 15854902-Fig-S2
  *** xEif4ebp1[phosAb] phos(T73)[phosAb] is detectable
    *** cells: HEK293<xEif4ebp1> in BMLS
    *** enhanced by: Ins (30 min) [stim]
    *** unaffected by: Rapamycin (30 min) [stim]
    *** source: 12588975-Fig-4d
  *** xEif4ebp1[tAb] copptby[WB] xRaptor[tAb] is detectable
    *** cells: HEK293<xRaptor><xEif4ebp1> in BMS
    *** comment: IP was washed with high salt buffer without detergent
    *** unaffected by: xMtor [addition]
    *** source: 12150926-Fig-4b
  *** xEif4ebp1[tAb] copptby[WB] xRaptor[tAb] is detectable
    *** cells: HEK293<xRaptor><xEif4ebp1> in BMS
    *** enhanced by: xEif4ebp1(T37A/T46A/S65A/T70A/S83A) [substitution]
    *** inhibited by: xEif4ebp1(T37E/T46E/S65E/T70E/S83E) [substitution]
    *** comment: IP was washed with high salt buffer containing NP40
    *** source: 12150926-Fig-5c
  *** xEif4ebp1[tAb] phos[WBMS] is decreased itpo xPras40
    *** cells: HEK293T<xEif4ebp1> in BMS
    *** source: 17277771-Fig-2c
  *** xEif4ebp1[tAb] phos[WBMS] is increased itpo xRheb
    *** cells: HEK293<xEif4ebp1> in BMS
    *** inhibited by: xTsc1 + xTsc2 [addition]
    *** source: 12869586-Fig-3b
  *** xEif4ebp1[tAb] phos[WBMS] is increased itpo xRheb
    *** cells: HEK293<xEif4ebp1> in BMS
    *** source: 12869586-Fig-2a
  *** xEif4ebp1[tAb]IP phos(T37)[phosAb] is increased itpo xYwhab
    *** cells: HEK293<xS6k1> in BMS
    *** source: 12364343-Fig-4e
  *** xEif4ebp1[tAb]IP phos[32Pi] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xEif4ebp1(T37A) [substitution]
    *** inhibited by: xEif4ebp1(T46A) [substitution]
    *** inhibited by: xEif4ebp1(T37A/T46A) [substitution]
    *** inhibited by: xEif4ebp1(T37E/T46E) [substitution]
    *** source: 10364159-Fig-10
*** Eif4ebp2--
  *** rEif4ebp2[32P] phos[32P-ATP] is increased by xMtor[tAb]IP
    *** cells: none
    *** IPfrom: HEK293<xMtor> in BMS
    *** inhibited by: xMtor(D2357E)"KD" [substitution]
    *** source: 9465032-Fig-4a
*** Eif4g1--
  *** Eif4g1[Ab] copptby[WB] xMnk2[Ab] is detectable
    *** cells: HEK293<xMnk2> in BMS
    *** enhanced by: xMnk2(1-455) [substitution]
    *** unaffected by: xMnk2(1-446) [substitution]
    *** source: 12897141-Fig-6e
  *** Eif4g1[Ab] copptby[WB] xMnk2[Ab] is detectable
    *** cells: HEK293<xMnk2> in BMS
    *** inhibited by: xMnk2(del(60-70))"delBR" [substitution]
    *** inhibited by: xMnk2(K60A/K61A/R62A) [substitution]
    *** inhibited by: xMnk2(K64A/K66A/K67A) [substitution]
    *** source: 12897141-Fig-2b
  *** Eif4g1[Ab] copptby[WB] xMnk2[Ab] is detectable
    *** cells: HEK293<xMnk2> in BMS
    *** unaffected by: xMnk2(1-455) [substitution]
    *** unaffected by: xMnk2(1-446) [substitution]
    *** unaffected by: xMnk2(R447A/R448A) [substitution]
    *** unaffected by: xMnk2(1-446) [substitution]
    *** source: 12897141-Fig-6d
  *** Eif4g1[Ab] copptby[WB] xMnk2[tAb] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: xMnk2(T197A) [substitution]
    *** unaffected by: xMnk2(T202A) [substitution]
    *** unaffected by: xMnk2(T332A) [substitution]
    *** unaffected by: xMnk2(T332D) [substitution]
    *** unaffected by: xMnk2(T403A) [substitution]
    *** unaffected by: xMnk2(T403D) [substitution]
    *** source: 11154262-Fig-4b
  *** Eif4g1[Ab] copptby[WB] xMnk2b[Ab] is detectable
    *** cells: HEK293<xMnk2b> in BMS
    *** inhibited by: xMnk2b(del(60-70))"delBR" [substitution]
    *** source: 12897141-Fig-2b
  *** Eif4g1[Ab] snaggedby[WB] capped-mRNA[m7GTP] is detectable
    *** cells: mESCs in BMLS
    *** does not req: Pdpk1 [KO]
    *** source: 11500364-Fig-2b
  *** xEif4g1[tAb] copptby[WB] Eif3b[Ab] is detectable
    *** cells: HEK293T in BMLS "AminoAcid deprived"
    *** unaffected by: xEif4b [addition]
    *** unaffected by: xS6k1 [addition]
    *** source: 16541103-Fig-6d
  *** xEif4g1[tAb] copptby[WB] xEif4e[tAb] is detectable
    *** cells: HEK293T in BMLS "AminoAcid deprived"
    *** inhibited by: xEif4g1(L617A/L618A)"Eif4e-binding-mut" [substitution]
    *** source: 16541103-Fig-4b
  *** xEif4g1[tAb] snaggedby[WB] capped-mRNA[m7GTP] is detectable
    *** cells: HEK293T<xEif4e> in BMLS "AminoAcid deprived"
    *** inhibited by: xEif4g1(L617A/L618A)"Eif4e-binding-mut" [substitution]
    *** source: 16541103-Fig-4a
*** Elf1--
  *** Elf1[Ab] snaggedby[WB] oligo[biotin] is detectable
    *** cells: hPHAblasts in BMS "IL2-deprived"
    *** oligo: "IL2Ra-GASd/EBSd" 5-TTTCTTCTAGGAAGTACC-3
    *** unaffected by: IL2 (30 min) [stim]
    *** source: 8943338-Fig-5
  *** Elf1[Ab] snaggedby[WB] oligo[biotin] is undetectable
    *** cells: hPHAblasts in BMS "IL2-deprived"
    *** oligo: "FcgRI-GAS" 5-GTATTTCCCAGAAAAGGAAC-3
    *** unaffected by: IL2 (30 min) [stim]
    *** source: 8943338-Fig-5
  *** rElk1 oligo-binding[EMSA] is decreased by rId2
    *** cells: none
    *** comment: reaction contains rSrf which remains oligo-bound itpo rId2
    *** source: 10022839-Fig-4a
*** Elk1--
  *** Elk1-gene mRNA[RTPCR] is detectable
    *** cells: mEFs in BMS
    *** partially reqs: Med23 [KO]
    *** source: 19417246-Fig-3
  *** Elk1-gene mRNA[RTPCR] is detectable
    *** cells: mESCs in BMS
    *** does not req: Med23 [KO]
    *** source: 19417246-Fig-3
  *** Elk1-reporter[Luc] is increased itpo xHras(G12V)
    *** cells: HEK293 in BMS
    *** partially inhibited by: xIL17Rd [addition]
    *** partially inhibited by: xIL17Rd(Y330F) [addition]
    *** source: 15239952-Fig-1b
  *** Elk1-reporter[Luc] is increased itpo xHras(G12V)
    *** cells: HEK293 in BMS
    *** partially inhibited by: xSpred1 [addition]
    *** source: 15239952-Fig-1b
  *** Elk1-reporter[Luc] is increased itpo xMek?(mnr)"SDSE"
    *** cells: HEK293 in BMS
    *** partially inhibited by: xIL17Rd [addition]
    *** partially inhibited by: xIL17Rd(Y330F) [addition]
    *** source: 15239952-Fig-1b
  *** Elk1-reporter[Luc] is increased itpo xMek?(mnr)"SDSE"
    *** cells: HEK293 in BMS
    *** unaffected by: xSpred1 [addition]
    *** source: 15239952-Fig-1b
  *** Elk1-reporter[Luc] is increased itpo xMek?(mnr)"SDSE"
    *** cells: HELA in BMS
    *** repressed by: IL17Rd [RNAi]
    *** source: 15239952-Fig-6b
  *** xElk1(205-399)[tAb] copptby[WB] xPias2a[tAb] is detectable
    *** cells: HEK293<xPias2a><xElk1(205-399)> in BMLS
    *** inhibited by: xElk1(205-375) [substitution]
    *** source: 15920481-Fig-4e
  *** xElk1(205-428)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMek1(mnr)"CA"
    *** cells: HEK293 in BMS
    *** enhanced by: xPias2a [addition]
    *** source: 16713578-Fig-5a
  *** xElk1(205-428)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xPias2a
    *** cells: HEK293 in BMS
    *** source: 16713578-Fig-5a
  *** rElk1(205-428){sumo} upshift[WBMS] is unchanged by xSenp3[tAb]IP
    *** cells: none
    *** IPfrom: HEK293T<xSenp3> in BMS
    *** source: 20337593-Fig-3c
  *** xElk1(223-428)[Gal4-DBD] Gal4-reporter[Luc] is decreased itpo xHdac1
    *** cells: HEK293 in BMS
    *** source: 14992729-Fig-1e
  *** xElk1(223-428)[Gal4-DBD] Gal4-reporter[Luc] is decreased itpo xHdac2
    *** cells: HEK293 in BMS
    *** source: 14992729-Fig-1e
  *** xElk1(223-428)[Gal4-DBD] Gal4-reporter[Luc] is detectable
    *** cells: HEK293 in BMS
    *** enhanced by: TrichostatinA [addition]
    *** enhanced by: xUbe2i(mnr)"DN" [addition]
    *** source: 14992729-Fig-S1
  *** xElk1(223-428)[Gal4-DBD] Gal4-reporter[Luc] is detectable
    *** cells: HEK293 in BMS
    *** enhanced by: xElk1((223-428)/K230R/K249R) [substitution]
    *** source: 14992729-Fig-S1
  *** xElk1(223-428)[Gal4-DBD] Gal4-reporter[Luc] is increased itao Hdac2 [RNAi]
    *** cells: HEK293 in BMS
    *** partially inhibited by: PMA [addition]
    *** inhibited by: xUbe2i(mnr)"DN" [addition]
    *** source: 14992729-Fig-2f
  *** xElk1(223-428)[Gal4-DBD] Gal4-reporter[Luc] is increased itao Hdac2 [RNAi]
    *** cells: HEK293 in BMS
    *** source: 14992729-Fig-2c
  *** xElk1(223-428)[Gal4-DBD] Gal4-reporter[Luc] is increased itao Hdac2 [RNAi]
    *** cells: HEK293 in BMS
    *** source: 14992729-Fig-2e
  *** xElk1(223-428)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xPias2a
    *** cells: HEK293 in BMLS
    *** source: 15920481-Fig-2e
  *** xElk1(223-428)[Gal4-DBD] Gal4-reporter[Luc] is unchanged itao Hdac1 [RNAi]
    *** cells: HEK293 in BMS
    *** source: 14992729-Fig-2c
  *** xElk1(223-428)[Gal4-DBD] Gal4-reporter[Luc] is unchanged itao Hdac3 [RNAi]
    *** cells: HEK293 in BMS
    *** source: 14992729-Fig-2c
  *** xElk1(223-428)[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xHdac3
    *** cells: HEK293 in BMS
    *** source: 14992729-Fig-1e
  *** xElk1(230-428)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xSenp3
    *** cells: HEK293 in BMS
    *** inhibited by: xElk1(260-428) [substitution]
    *** source: 12887893-Fig-2c
  *** xElk1(230-428)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xUbe2i(C35S)"DN"
    *** cells: HEK293 in BMS
    *** inhibited by: xElk1(260-428) [substitution]
    *** source: 12887893-Fig-2b
  *** xElk1(260-428)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xPias2a
    *** cells: HEK293 in BMLS
    *** enhanced by: xElk1(260-428){sumo} [substitution]
    *** source: 15920481-Fig-2d
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[CAT] is increased itpo xMekk1
    *** cells: HELA in BMLS
    *** inhibited by: xElk1(TAD/S383A/S389A) [substitution]
    *** source: 8846788-Fig-6
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is decreased itao Ppp2r1a [RNAi]
    *** cells: PC63 in BMHIS "treated with Egf for 5 hr"
    *** source: 16129692-Fig-2d
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is decreased itao Ppp2r1a [RNAi]
    *** cells: PC63 in BMHIS "treated with Fgf2 for 5 hr"
    *** source: 16129692-Fig-2d
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is decreased itao Ppp2r1a [RNAi]
    *** cells: PC63 in BMHIS "treated with Ngf for 5 hr"
    *** source: 16129692-Fig-2d
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is detectable
    *** cells: COS1<xBraf> in BMLS
    *** unaffected by: xBraf(T598A/S601A) [substitution]
    *** enhanced by: xBraf(T598E/S601D) [substitution]
    *** source: 11032810-Fig-4b
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is detectable
    *** cells: HEK293<xBraf> in BMLS
    *** enhanced by: LY294002 [pretreatment]
    *** source: 10869359-Fig-4b
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is detectable
    *** cells: HEK293<xBraf> in BMLS
    *** enhanced by: xBraf(S364A) [substitution]
    *** enhanced by: xBraf(S428A/T439A) [substitution]
    *** enhanced by: xBraf(S364A/S428A/T439A) [substitution]
    *** source: 10869359-Fig-4
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is detectable
    *** cells: NIH3T3 in BMS
    *** partially inhibited by: xRap1a(S17N)"DN" [addition]
    *** partially inhibited by: xRala(S28N)"DN" [addition]
    *** source: 12734187-Fig-8b
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itao Ppp2r1a [RNAi]
    *** cells: PC63<xHras(G12V)"CA"> in BMHIS
    *** source: 16129692-Fig-1b
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itao Ppp2r1a [RNAi]
    *** cells: PC63<xMek1(S218D/S222D)"CA"> in BMHIS
    *** source: 16129692-Fig-1b
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo (xBraf + xPkac?)
    *** cells: NIH3T3 in BMLS
    *** reqs: both [omission]
    *** source: 9094716-Fig-3b
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo (xRac1(Q61L)"CA" + xRaf1)
    *** cells: NIH3T3 in BMS
    *** reqs: xRaf1 [omission]
    *** partially reqs: xRac1(Q61L)"CA" [omission]
    *** partially inhibited by: xErk2(K52R)"DN" [addition]
    *** unaffected by: xJnk3(mnr)"DN" [addition]
    *** source: 9351825-Fig-2a,2b,3b
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xCdc42(Q61L)"CA"
    *** cells: NIH3T3 in BMS
    *** enhanced by: xRaf1 [addition]
    *** source: 9351825-Fig-2a,2b
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xHras
    *** cells: HEK293T in BMS
    *** source: 10913189-Fig-7
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xHras
    *** cells: NIH3T3 in BMS
    *** enhanced by: xSos1 [addition]
    *** source: 8887643-Fig-4a
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xHras(G12V)"CA"
    *** cells: HEK293 in BMS
    *** unaffected by: xRgl3 [addition]
    *** unaffected by: xRgl2 [addition]
    *** source: 11313946-Fig-5a
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xHras(G12V)"CA"
    *** cells: HEK293T in BMS
    *** inhibited by: xRap2a [addition]
    *** inhibited by: xRap2a(G12V)"CA" [addition]
    *** partially inhibited by: xRap1a [addition]
    *** inhibited by: xRap1a(G12V)"CA" [addition]
    *** source: 10913189-Fig-7
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xHras(G12V)"CA"
    *** cells: HEK293T in BMS
    *** partially inhibited by: xRasGrp2 [addition]
    *** source: 9789079-Fig-3
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xHras(G12V)"CA"
    *** cells: HTTA in BMS
    *** inhibited by: xRig1 [addition]
    *** unaffected by: xRig1(del(Cterm)) [addition]
    *** source: 16005186-Fig-6a
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xHras(Q61L)"CA"
    *** cells: NIH3T3 in BMLS
    *** inhibited by: PD98059 [addition]
    *** unaffected by: SB203580 [addition]
    *** source: 10446149-Fig-6a
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xHras(Q61L)"CA"
    *** cells: NIH3T3 in BMS
    *** enhanced by: xRaf1 [addition]
    *** source: 8887643-Fig-5
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xHras(Q61L)"CA"
    *** cells: NIH3T3 in BMS
    *** inhibited by: xRalGds [addition]
    *** source: 11788587-Fig-3a
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xIrak4
    *** cells: HEK293 in BMS
    *** source: 11960013-Fig-3a
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xKras(G12V)"CA"
    *** cells: HEK293 in BMLS
    *** source: 10869359-Fig-4b
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMek1(mnr)"CA"
    *** cells: NIH3T3 in BMLS
    *** inhibited by: PD98059 [addition]
    *** unaffected by: SB203580 [addition]
    *** source: 10446149-Fig-6a
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMek1(S218D/S22D)"CA"
    *** cells: COS1 in BMLS
    *** enhanced by: xErk2 [addition]
    *** source: 12594221-Fig-1c
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMek1(S218E/S222E)"CA"
    *** cells: NIH3T3 in BMS
    *** unaffected by: xJip1 [addition]
    *** source: 10669751-Fig-3b
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMek1(S218E/S222E/del(32-51))"CA"
    *** cells: HTTA in BMS
    *** unaffected by: xRig1 [addition]
    *** unaffected by: xRig1(del(Cterm)) [addition]
    *** source: 16005186-Fig-6a
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMek2(mnr)"CA"
    *** cells: NIH3T3 in BMS
    *** unaffected by: xRalGds [addition]
    *** source: 11788587-Fig-3a
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMekk1
    *** cells: HEK293 in BMS
    *** inhibited by: xRgl3 [addition]
    *** unaffected by: xRgl2 [addition]
    *** source: 11313946-Fig-5b
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMekk1
    *** cells: NIH3T3 in BMS
    *** inhibited by: xJip1 [addition]
    *** source: 10669751-Fig-3b
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMekk1(mnr)"CA"
    *** cells: mEFs in BMS
    *** reqs: Med23 [KO]
    *** source: 19417246-Fig-5e
  *** Elk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMekk1(mnr)"CA"
    *** cells: mESCs in BMS
    *** reqs: Med23 [KO]
    *** source: 11934987-Fig-3b
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMekk1(mnr)"CA"
    *** cells: mESCs in BMS
    *** reqs: Med23 [KO]
    *** source: 19417246-Fig-5b
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMkk3(S189E/T193E)"CA"
    *** cells: CHO in BMS
    *** source: 8663524-Fig-9
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMkk6(S207E/T211E)"CA"
    *** cells: CHO in BMS
    *** enhanced by: xP38a [addition]
    *** source: 9430721-Fig-8a
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMkk6(S207E/T211E)"CA"
    *** cells: CHO in BMS
    *** enhanced by: xP38b [addition]
    *** source: 9430721-Fig-8b
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMkk6(S207E/T211E)"CA"
    *** cells: CHO in BMS
    *** enhanced by: xP38g [addition]
    *** source: 9430721-Fig-8c
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMkk6(S207E/T211E)"CA"
    *** cells: CHO in BMS
    *** source: 8663524-Fig-9
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMras(G22V)"CA"
    *** cells: HEK293 in BMS
    *** inhibited by: xRgl3 [addition]
    *** unaffected by: xRgl2 [addition]
    *** source: 11313946-Fig-5d
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMras(Q71L)"CA"
    *** cells: NIH3T3 in BMLS
    *** inhibited by: PD98059 [addition]
    *** unaffected by: SB203580 [addition]
    *** source: 10446149-Fig-6a
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMyd88
    *** cells: HEK293 in BMS
    *** source: 11544529-Fig-2c
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xPeli2
    *** cells: HEK293 in BMS
    *** source: 12804775-Fig-2a
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xRaf1
    *** cells: COS7<xAgtR1> in BMLS
    *** inhibited by: xArrb1 [addition]
    *** inhibited by: xArrb2 [addition]
    *** source: 11777902-Fig-5c
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xRaf1
    *** cells: HEK293 in BMS
    *** unaffected by: xRgl3 [addition]
    *** unaffected by: xRgl2 [addition]
    *** source: 11313946-Fig-5c
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xRaf1
    *** cells: NIH3T3 in BMLS
    *** inhibited by: xRap1a(G12V)"CA" [addition]
    *** inhibited by: Forskolin [addition]
    *** source: 9094716-Fig-3e
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xRaf1
    *** cells: NIH3T3 in BMS
    *** unaffected by: xErk2(K52R)"DN" [addition]
    *** unaffected by: xJnk3(mnr)"DN" [addition]
    *** enhanced by: xRac1(Q61L)"CA" [addition]
    *** enhanced by: xCdc42(Q61L)"CA" [addition]
    *** unaffected by: xRhoa(Q63L)"CA" [addition]
    *** source: 9351825-Fig-2b,2c,4b
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xRaf1(del(66-303))"CA"
    *** cells: NIH3T3 in BMS
    *** source: 9351825-Fig-2a
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xRaf1(mnr)"CA"
    *** cells: HEK293T in BMS
    *** unaffected by: xRap2a [addition]
    *** unaffected by: xRap2a(G12V)"CA" [addition]
    *** source: 10913189-Fig-7
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xRaf1(mnr)"CAAX"
    *** cells: NIH3T3 in BMS
    *** inhibited by: xPea15 [addition]
    *** unaffected by: xPea15(D74A) [addition]
    *** source: 11702783-Fig-7c
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xRap1a(G12V)"CA"
    *** cells: NIH3T3 in BMLS
    *** enhanced by: xBraf [addition]
    *** source: 9094716-Fig-5d
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xRap1a(G12V)"CA"
    *** cells: PC12 in BMLS
    *** inhibited by: xMek1(K97R)"DN" [addition]
    *** unaffected by: xHras(S17N)"DN" [addition]
    *** enhanced by: xBraf [addition]
    *** source: 9094716-Fig-4a
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xRap1a(Q63E)"CA"
    *** cells: LNCAP in BMS
    *** source: 10934204-Fig-4
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xRapGef1
    *** cells: LNCAP in BMS
    *** source: 10934204-Fig-4
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xRapGef2
    *** cells: LNCAP in BMS
    *** source: 10934204-Fig-4
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xRapGef5
    *** cells: LNCAP in BMS
    *** source: 10934204-Fig-4
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xRasGrp1
    *** cells: HEK293T in BMS
    *** source: 9789079-Fig-3
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xRasGrp3
    *** cells: LNCAP in BMS
    *** source: 10934204-Fig-4
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xRras2
    *** cells: NIH3T3 in BMS
    *** enhanced by: xSos1 [addition]
    *** source: 8887643-Fig-4b
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xRras2(Q72L)"CA"
    *** cells: NIH3T3 in BMS
    *** enhanced by: xRaf1 [addition]
    *** source: 8887643-Fig-5
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xRras2(Q72L)"CA"
    *** cells: NIH3T3 in BMS
    *** inhibited by: xRalGds [addition]
    *** source: 11788587-Fig-3a
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xSos1
    *** cells: NIH3T3 in BMS
    *** enhanced by: xHras [addition]
    *** source: 8887643-Fig-4a
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xSos1
    *** cells: NIH3T3 in BMS
    *** enhanced by: xRras2 [addition]
    *** source: 8887643-Fig-4b
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xTirap
    *** cells: HEK293 in BMS
    *** source: 11544529-Fig-2c
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xTpl2
    *** cells: NIH3T3 in BMS
    *** inhibited by: xJip1 [addition]
    *** source: 10669751-Fig-3b
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is unchanged itao Ppp2r1a [RNAi]
    *** cells: PC63 in BMHIS
    *** source: 16129692-Fig-1a
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xBraf
    *** cells: NIH3T3 in BMLS
    *** source: 9094716-Fig-3b
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xMek1
    *** cells: HEK293 in BMS
    *** source: 11960013-Fig-3a
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xMkk3(S218E/T222E)"CA"
    *** cells: CHO in BMS
    *** source: 9430721-Fig-8a
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xMkk3(S218E/T222E)"CA"
    *** cells: CHO in BMS
    *** source: 9430721-Fig-8b
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xMkk3(S218E/T222E)"CA"
    *** cells: CHO in BMS
    *** source: 9430721-Fig-8c
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xPeli1
    *** cells: HEK293 in BMS
    *** source: 12804775-Fig-2b
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xPkac?
    *** cells: NIH3T3 in BMLS
    *** source: 9094716-Fig-3b
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xRac1(Q61L)"CA"
    *** cells: NIH3T3 in BMS
    *** enhanced by: xRaf1 [addition]
    *** source: 9351825-Fig-2a,2b,3b
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xRap1Gds1
    *** cells: LNCAP in BMS
    *** source: 10934204-Fig-4
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xRasGrp2
    *** cells: HEK293T in BMS
    *** source: 9789079-Fig-3
  *** xElk1(TAD)[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xRhoa(Q63L)"CA"
    *** cells: NIH3T3 in BMS
    *** source: 9351825-Fig-2a,2b
  *** xElk1(TAD)[XFP] colocwith[IHC] xMed6[XFP] is detectable
    *** cells: CHOA031 in BMLS
    *** unaffected by: xElk1(TAD/S383A) [substitution]
    *** unaffected by: xElk1(TAD/S383A/S389A) [substitution]
    *** unaffected by: xElk1(TAD/S383A/S389A/T363A/T368A) [substitution]
    *** inhibited by: xElk1(TAD/F378A/W379A) [substitution]
    *** source: 19417246-Fig-6e
  *** xElk1(TAD)[XFP] colocwith[IHC] xMed6[XFP] is detectable
    *** cells: CHOA031<xMekk1(mnr)"CA"> in BMLS
    *** unaffected by: xElk1(TAD/S383A) [substitution]
    *** unaffected by: xElk1(TAD/S383A/S389A) [substitution]
    *** source: 19417246-Fig-S8a
  *** rElk1[35S] boundby[WB] rId2[GST] is detectable
    *** cells: none
    *** source: 10022839-Fig-1b
  *** rElk1[35S] boundby[WB] rUbe2i[GST] is detectable
    *** cells: none
    *** source: 15210726-Fig-1b
  *** Elk1[Ab] boundto(Cdc11a-gene)[ChIP] is undetectable
    *** cells: HCT116 in BMS
    *** source: 15498926-Fig-4a
  *** Elk1[Ab] boundto(Cdc11a-gene)[ChIP] is undetectable
    *** cells: JURKAT<Pten~null> in BMS
    *** source: 15498926-Fig-4a
  *** Elk1[Ab] boundto(Egr1-gene)[ChIP] is detectable
    *** cells: HCT116 in BMS
    *** source: 15498926-Fig-4a
  *** Elk1[Ab] boundto(Egr1-gene)[ChIP] is detectable
    *** cells: HELA in BMLS
    *** unaffected by: PMA (5 min) [stim]
    *** source: 11531578-Fig-6
  *** Elk1[Ab] boundto(Egr1-gene)[ChIP] is detectable
    *** cells: JURKAT<Pten~null> in BMS
    *** source: 15498926-Fig-4a
  *** Elk1[Ab] boundto(Egr1-gene)[ChIP] is detectable
    *** cells: mESCs in BMS
    *** comment: both the -400 and -100 Egr1-gene SRE clusters were detected
    *** source: 19417246-Fig-S5
  *** Elk1[Ab] boundto(Egr1-gene)[ChIP] is detectable
    *** cells: mESCs<Med23~null> in BMS
    *** comment: both the -400 and -100 Egr1-gene SRE clusters were detected
    *** source: 19417246-Fig-4
  *** Elk1[Ab] boundto(Srf-gene)[ChIP] is detectable
    *** cells: HELA in BMLS
    *** unaffected by: PMA (5 min) [stim]
    *** source: 11531578-Fig-6
  *** xElk1[Gal4-DBD] Gal4-reporter[CAT] is increased itpo xMekk1
    *** cells: NIH3T3 in BMLS
    *** source: 8548291-Fig-6c
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is decreased itao Pias2a [RNAi]
    *** cells: HELA in BMLS
    *** source: 15920481-Fig-1d
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is decreased itpo xDusp6
    *** cells: CCL39 in BMLS
    *** partially reversed by: xDusp6(C293S) [substitution]
    *** source: 9927426-Fig-5b
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is decreased itpo xDusp6
    *** cells: CCL39<xErk1> in BMLS
    *** reversed by: xDusp6(C293S) [substitution]
    *** source: 9927426-Fig-5b
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is decreased itpo xDusp6
    *** cells: CCL39<xJnk1> in BMLS
    *** partially reversed by: xDusp6(C293S) [substitution]
    *** source: 9927426-Fig-5b
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is decreased itpo xDusp6
    *** cells: CCL39<xP38a> in BMLS
    *** partially reversed by: xDusp6(C293S) [substitution]
    *** source: 9927426-Fig-5b
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is detectable
    *** cells: HEK293 in BMS
    *** enhanced by: xElk1(K230R/K249R) [substitution]
    *** source: 12887893-Fig-1c
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is detectable
    *** cells: HEK293 in BMS
    *** enhanced by: xElk1(K230R/K249R) [substitution]
    *** source: 12887893-Fig-2d
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itao Ube2i [RNAi]
    *** cells: HEK293 in BMS
    *** source: 12887893-Fig-2f
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xCdc42(Q61L)
    *** cells: CHO in BMLS
    *** bkg inhibited by: xDusp1 [addition]
    *** source: 9111305-Fig-8b
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xCdc42(Q61L)
    *** cells: CHO in BMLS
    *** bkg inhibited by: xMkk4(mnr)"DN" [addition]
    *** source: 9111305-Fig-8d
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xCdc42(Q61L)
    *** cells: CHO in BMLS
    *** inhibited by: xElk1(S383A)[Gal4-DBD] [substitution]
    *** source: 9111305-Fig-8b
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xCdc42(Q61L)
    *** cells: CHO in BMLS
    *** unaffected by: SB203580 [addition]
    *** source: 9111305-Fig-8d
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xEp300
    *** cells: HEK293 in BMLS "treated with PMA for 6 hr"
    *** enhanced by: xPias2a [addition]
    *** source: 15920481-Fig-7e
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xEp300
    *** cells: HEK293 in BMLS "treated with PMA for 6 hr"
    *** reqs: Pias2a [RNAi]
    *** source: 15920481-Fig-7f
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xGab2
    *** cells: KIT225 in BMS "IL2-deprived"
    *** inhibited by: xGab2(Y614F) [substitution]
    *** source: 15170389-Fig-3b
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xGam1!Adeg1
    *** cells: HEK293 in BMS
    *** source: 12887893-Fig-2e
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xHras(Q61L)
    *** cells: CHO in BMLS
    *** unaffected by: xMkk4(mnr)"DN" [addition]
    *** source: 9111305-Fig-8e
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xLamtor3
    *** cells: COS<xMek1(S218D/S222D)><xErk1> in BMLS
    *** reqs: xMek1(S218D/S222D) [omission]
    *** reqs: xErk1 [omission]
    *** source: 9733512-Fig-5
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMek1(del(32-51)/S218E/S222D)
    *** cells: CHO in BMS
    *** source: 8622669-Fig-4d
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMek1(del(32-51)/S218E/S222E)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-3b
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMek1(mnr)"CA"
    *** cells: CHO in BMLS
    *** inhibited by: xElk1(S383A)[Gal4-DBD] [substitution]
    *** source: 9111305-Fig-4
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMek1(mnr)"CA"
    *** cells: CHO in BMLS
    *** unaffected by: SB203580 [addition]
    *** source: 9111305-Fig-4
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMek1(S218D/S222D)
    *** cells: COS in BMLS
    *** unaffected by: xLamtor3 [addition]
    *** source: 9733512-Fig-5
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMekk1
    *** cells: CHO in BMLS
    *** inhibited by: xElk1(S383A)[Gal4-DBD] [substitution]
    *** source: 9111305-Fig-4
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMekk1
    *** cells: CHO in BMLS
    *** unaffected by: SB203580 [addition]
    *** source: 9111305-Fig-4
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMkk6(mnr)"CA"
    *** cells: CHO in BMLS
    *** inhibited by: SB203580 [addition]
    *** source: 9111305-Fig-4
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMkk6(mnr)"CA"
    *** cells: CHO in BMLS
    *** inhibited by: xElk1(S383A)[Gal4-DBD] [substitution]
    *** source: 9111305-Fig-4
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xPias2
    *** cells: HEK293 in BMLS
    *** source: 15920481-Fig-2a
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xPias2a
    *** cells: HEK293 in BMLS
    *** enhanced by: U0126 [addition]
    *** source: 15920481-Fig-5c
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xPias2a
    *** cells: HEK293 in BMLS
    *** inhibited by: xElk1(K230R/K249R) [substitution]
    *** source: 15920481-Fig-2b
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xPias2a
    *** cells: HEK293 in BMLS
    *** inhibited by: xUbe2i(mnr)"DN" [addition]
    *** source: 15920481-Fig-2c
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xPias2a
    *** cells: HEK293 in BMLS
    *** partially inhibited by: xPias2a(103-572) [substitution]
    *** partially inhibited by: xPias2a(304-572) [substitution]
    *** source: 15920481-Fig-6e
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xPias2a
    *** cells: HEK293 in BMLS
    *** source: 15920481-Fig-2a
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xPias2a
    *** cells: HEK293 in BMLS
    *** unaffected by: xPias2a(W383A) [substitution]
    *** inhibited by: xPias2a(del(467-487)) [substitution]
    *** source: 15920481-Fig-6b
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xPias2a
    *** cells: HEK293 in BMLS "treated with PMA for 6 hr"
    *** source: 15920481-Fig-7d
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xPias2a
    *** cells: HEK293<xEp300> in BMLS "treated with PMA for 6 hr"
    *** inhibited by: xEp300(del(831-1045)) [substitution]
    *** source: 15920481-Fig-7d
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xRac1(Q61L)
    *** cells: CHO in BMLS
    *** bkg inhibited by: xDusp1 [addition]
    *** source: 9111305-Fig-8b
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xRac1(Q61L)
    *** cells: CHO in BMLS
    *** inhibited by: xElk1(S383A)[Gal4-DBD] [substitution]
    *** source: 9111305-Fig-8b
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xRhoa(Q61L)
    *** cells: CHO in BMLS
    *** bkg inhibited by: xDusp1 [addition]
    *** source: 9111305-Fig-8b
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xRhoa(Q61L)
    *** cells: CHO in BMLS
    *** inhibited by: xElk1(S383A)[Gal4-DBD] [substitution]
    *** source: 9111305-Fig-8b
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xSenp2
    *** cells: HEK293T in BMS
    *** inhibited by: xElk1(K230R/K249R) [substitution]
    *** source: 20337593-Fig-1c
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xSenp2
    *** cells: HEK293T in BMS
    *** unaffected by: xSenp2(mnr)"CIA" [substitution]
    *** source: 20337593-Fig-1e
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xSenp3
    *** cells: HEK293T in BMS
    *** inhibited by: xElk1(K230R/K249R) [substitution]
    *** source: 20337593-Fig-1c
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xSenp3
    *** cells: HEK293T in BMS
    *** inhibited by: xSenp3(mnr)"CIA" [substitution]
    *** source: 20337593-Fig-1e
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xUbe2i(C35S)"DN"
    *** cells: HEK293 in BMS
    *** source: 12887893-Fig-2d
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xFoxp3
    *** cells: HEK293T in BMS
    *** source: 15790681-Fig-4d
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xFoxp3
    *** cells: mCD4TCs in BMS "treated with anti-Cd3 + anti-Cd28 (24 hr)"
    *** source: 15790681-Fig-5c
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xMekk1(380-672)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-3b
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xPias1
    *** cells: HEK293 in BMLS
    *** source: 15920481-Fig-2a
  *** xElk1[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xPias4
    *** cells: HEK293 in BMLS
    *** source: 15920481-Fig-2a
  *** xElk1[Gal4-DBD] locatedin(nucleus)[IHC] is detectable
    *** cells: CCL39 in BMLS
    *** source: 9927426-Fig-5a
  *** xElk1[His]IP sumo[tSuAb] is detectable
    *** cells: COS7<xElk1><xSumo1> in BMS
    *** inhibited by: xUbe2i(mnr)"DN" [addition]
    *** source: 15920481-Fig-5a
  *** xElk1[His]IP sumo[tSuAb] is detectable
    *** cells: HEK293<xElk1><xSumo1><xPias2a> in BMS "treated with Anisomycin for 40 min"
    *** inhibited by: xPias2a(S113A/S116A) [substitution]
    *** source: 16713578-Fig-6d
  *** xElk1[His]IP sumo[tSuAb] is detectable
    *** cells: HEK293<xElk1><xSumo1><xPias2a> in BMS "treated with Anisomycin for 40 min"
    *** inhibited by: xPias2a(W383A) [substitution]
    *** source: 16713578-Fig-6b
  *** xElk1[His]IP sumo[tSuAb] is detectable
    *** cells: HEK293<xElk1><xSumo1><xPias2a> in BMS "treated with Anisomycin for 40 min"
    *** reqs: Pias2a [RNAi]
    *** source: 16713578-Fig-6c
  *** xElk1[His]IP sumo[tSuAb] is detectable-but unchanged itpo xPias2a
    *** cells: COS7<xElk1><xSumo1> in BMS
    *** source: 15920481-Fig-5a
  *** xElk1[phosAb] phos(S383)[phosAb] is increased itpo xMkk6(S207E/T211E)"CA"
    *** cells: COS7<xP38a> in BMS
    *** source: 9430721-Fig-8e
  *** xElk1[phosAb] phos(S383)[phosAb] is increased itpo xMkk6(S207E/T211E)"CA"
    *** cells: COS7<xP38b> in BMS
    *** source: 9430721-Fig-8e
  *** xElk1[phosAb] phos(S383)[phosAb] is increased itpo xMkk6(S207E/T211E)"CA"
    *** cells: COS7<xP38g> in BMS
    *** source: 9430721-Fig-8e
  *** xElk1[phosAb] phos(S383)[phosAb] is unchanged itpo xPias2a
    *** cells: COS7<xElk1> in BMS
    *** source: 15920481-Fig-5b
  *** Elk1[phosAb] phos(sitenr)[phosAb] is decreased itpo xPea15
    *** cells: NIH3T3 in BMS "treated with serum"
    *** source: 11702783-Fig-1a
  *** Elk1[tAb] boundto(Egr1-gene)[ChIP] is detectable
    *** cells: HELA in BMS
    *** unaffected by: PMA [addition]
    *** source: 14992729-Fig-4e
  *** Elk1[tAb] boundto(Egr1-gene)[ChIP] is detectable
    *** cells: HELA in BMS
    *** unaffected by: xUbe2i(mnr)"DN" [addition]
    *** source: 14992729-Fig-4e
  *** xElk1[tAb]IP phos(S383)[phosAb] is increased itpo xHras(G12V)
    *** cells: HELA<xElk1> in BMS
    *** times: 0 15++ 30+ min
    *** partially inhibited by: xIL17Rd [addition]
    *** unaffected by: xIL17Rd(1-356) [addition]
    *** source: 15239952-Fig-5d
  *** xElk1[tAb]IP phos(S383)[phosAb] is increased itpo xHras(G12V)
    *** cells: HELA<xElk1> in BMS
    *** times: 0 15++ 30+ min
    *** partially inhibited by: xSpred1 [addition]
    *** source: 15239952-Fig-5d
  *** xElk1[tAb]IP sumo[tSuAb] is decreased itpo xMek1(S218E/S222D)"CA"
    *** cells: COS7<xSumo?> in BMS
    *** source: 12887893-Fig-5a
  *** xElk1[tAb]IP sumo[tSuAb] is detectable
    *** cells: COS7<xSumo?> in BMS
    *** inhibited by: xElk1(K230R/K249R) [substitution]
    *** source: 12887893-Fig-5a
  *** rElk1{phos} oligo-binding[EMSA] is detectable
    *** cells: none
    *** comment: rElk1 was phosed with rErk2{act}
    *** inhibited by: rElk1 [substitution]
    *** source: 9111305-Fig-2a
  *** rElk1{phos} oligo-binding[EMSA] is detectable
    *** cells: none
    *** comment: rElk1 was phosed with rP38a{act}
    *** inhibited by: rElk1 [substitution]
    *** source: 9111305-Fig-2a
  *** rElk1{phos} oligo-binding[EMSA] is detectable
    *** cells: none
    *** comment: rElk1 was phosphorylated by rErk1{act}
    *** comment: rSrf was included in the reaction
    *** inhibited by: rElk1 [substitution]
    *** inhibited by: rElk1(S383A){phos} [substitution]
    *** source: 7889942-Fig-6
  *** rElk1{phos} oligo-binding[EMSA] is detectable
    *** cells: none
    *** comment: rElk1 was phosphorylated by rErk1{act}
    *** comment: rSrf was included in the reaction
    *** inhibited by: rElk1 [substitution]
    *** source: 7889942-Fig-5
  *** rElk1{phos} oligo-binding[EMSA] is detectable
    *** cells: none
    *** comment: rSrf(133-222) was present in the reaction
    *** comment: rElk1 was phosphorylated by Erk1-IP
    *** inhibited by: rElk1 [substitution]
    *** source: 8622654-Fig-1a
  *** rElk1{phos} oligo-binding[EMSA] is detectable
    *** cells: none
    *** comment: rSrf(133-222) was present in the reaction
    *** comment: rElk1 was phosphorylated by rErk1 phosed by rMek1(mnr)"CA"
    *** partially inhibited by: rElk1(S383A){phos} [substitution]
    *** source: 8622654-Fig-2
  *** rElk1{phos} oligo-binding[EMSA] is detectable
    *** cells: none
    *** comment: rSrf(133-222) was present in the reaction
    *** comment: rElk1 was phosphorylated by rErk2 phosed by rMek1(mnr)"CA"
    *** partially inhibited by: rElk1(S383A){phos} [substitution]
    *** source: 8622654-Fig-2
  *** Elk3-gene mRNA[RTPCR] is detectable
    *** cells: mEFs in BMS
    *** partially reqs: Med23 [KO]
    *** source: 19417246-Fig-3
  *** Elk3-gene mRNA[RTPCR] is detectable
    *** cells: mESCs in BMS
    *** does not req: Med23 [KO]
    *** source: 19417246-Fig-3
  *** rElk3[35S] boundby[WB] rId2[GST] is detectable
    *** cells: none
    *** source: 10022839-Fig-1b
  *** Elk3[Ab] boundto(Egr1-gene)[ChIP] is detectable
    *** cells: mEFs in BMS
    *** comment: both the -400 and -100 Egr1-gene SRE clusters were detected
    *** source: 19417246-Fig-S5
  *** Elk3[Ab] boundto(Egr1-gene)[ChIP] is detectable
    *** cells: mEFs<Med23~null> in BMS
    *** comment: both the -400 and -100 Egr1-gene SRE clusters were detected
    *** source: 19417246-Fig-4
  *** rElk4 oligo-binding[EMSA] is decreased by rId1
    *** cells: none
    *** comment: reaction contains rSrf which remains oligo-bound itpo rId2
    *** source: 10022839-Fig-4b
  *** rElk4 oligo-binding[EMSA] is decreased by rId2
    *** cells: none
    *** comment: reaction contains rSrf which remains oligo-bound itpo rId2
    *** source: 10022839-Fig-4a
  *** rElk4 oligo-binding[EMSA] is decreased by rId2
    *** cells: none
    *** comment: reaction contains rSrf which remains oligo-bound itpo rId2
    *** source: 10022839-Fig-4b
  *** rElk4 oligo-binding[EMSA] is decreased by rId3
    *** cells: none
    *** comment: reaction contains rSrf which remains oligo-bound itpo rId2
    *** source: 10022839-Fig-4b
  *** Elk4-gene mRNA[RTPCR] is detectable
    *** cells: mEFs in BMS
    *** does not req: Med23 [KO]
    *** source: 19417246-Fig-3
  *** Elk4-gene mRNA[RTPCR] is detectable
    *** cells: mESCs in BMS
    *** does not req: Med23 [KO]
    *** source: 19417246-Fig-3
  *** xElk4(234-431)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xPias2a
    *** cells: HEK293 in BMLS
    *** source: 15920481-Fig-2e
  *** xElk4(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMekk1(mnr)"CA"
    *** cells: mEFs in BMS
    *** does not req: Med23 [KO]
    *** source: 19417246-Fig-5g
  *** xElk4(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMekk1(mnr)"CA"
    *** cells: mEFs in BMS
    *** partially reqs: Med23 [KO]
    *** source: 19417246-Fig-5f
  *** xElk4(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMekk1(mnr)"CA"
    *** cells: mESCs in BMS
    *** does not req: Med23 [KO]
    *** source: 19417246-Fig-5d
  *** xElk4(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMekk1(mnr)"CA"
    *** cells: mESCs in BMS
    *** partially reqs: Med23 [KO]
    *** source: 19417246-Fig-5c
  *** xElk4(TAD)[XFP] colocwith[IHC] xMed6[XFP] is detectable
    *** cells: CHOA031<xMekk1(mnr)"CA"> in BMLS
    *** unaffected by: xElk4(TAD/S357A) [substitution]
    *** unaffected by: xElk4(TAD/S357A/S363A) [substitution]
    *** source: 19417246-Fig-S8a
  *** xElk4(TAD)[XFP] colocwith[IHC] xMed6[XFP] is detectable
    *** cells: CHOA031<xMekk1(mnr)"CA"> in BMLS
    *** unaffected by: xElk4(TAD/S381A) [substitution]
    *** unaffected by: xElk4(TAD/S381A/S387A) [substitution]
    *** source: 19417246-Fig-S8a
  *** rElk4[35S] boundby[WB] rId2[GST] is detectable
    *** cells: none
    *** source: 10022839-Fig-1b
  *** rElk4[35S] boundby[WB] rId2[GST] is detectable
    *** cells: none
    *** source: 10022839-Fig-3b
  *** Elk4[Ab] boundto(Egr1-gene)[ChIP] is detectable
    *** cells: mESCs in BMS
    *** comment: both the -400 and -100 Egr1-gene SRE clusters were detected
    *** source: 19417246-Fig-S5
  *** Elk4[Ab] boundto(Egr1-gene)[ChIP] is detectable
    *** cells: mESCs<Med23~null> in BMS
    *** comment: both the -400 and -100 Egr1-gene SRE clusters were detected
    *** source: 19417246-Fig-4
  *** xElk4[Gal4-DBD] Gal4-reporter[Luc] is increased itpo (xMkk3(mnr)"CA" + xP38a)
    *** cells: CHO in BMLS
    *** inhibited by: SB203580 [addition]
    *** source: 9111305-Fig-4
  *** xElk4[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMek1(mnr)"CA"
    *** cells: CHO in BMLS
    *** unaffected by: SB203580 [addition]
    *** source: 9111305-Fig-4
  *** xElk4[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMekk1
    *** cells: CHO in BMLS
    *** unaffected by: SB203580 [addition]
    *** source: 9111305-Fig-4
  *** xElk4[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMkk6(mnr)"CA"
    *** cells: CHO in BMLS
    *** inhibited by: SB203580 [addition]
    *** source: 9111305-Fig-4
  *** rElk4{phos} oligo-binding[EMSA] is detectable
    *** cells: none
    *** comment: rElk4 was phosed with rErk2{act}
    *** inhibited by: rElk4 [substitution]
    *** source: 9111305-Fig-2b
  *** rElk4{phos} oligo-binding[EMSA] is detectable
    *** cells: none
    *** comment: rElk4 was phosed with rP38a{act}
    *** inhibited by: rElk4 [substitution]
    *** source: 9111305-Fig-2b
*** Emr1--
  *** Emr1[Ab] surface-exp[FACS] is detectable
    *** cells: mBMMs in BMS
    *** unaffected by: Traf3 [KO]
    *** source: 16306936-Fig-S2a
  *** EndA1[Ab] copptby[WB] Cin85[Ab] is detectable
    *** cells: HELA in BMLS
    *** unaffected by: Egf (10 min) [stim]
    *** source: 12177062(D)
  *** xEndA1[tAb] copptby[WB] Cbl[Ab] is detectable
    *** cells: HEK293T in BMS
    *** source: 11894095-Fig-2a
  *** xEndA1[tAb] copptby[WB] EgfR[Ab] is increased itpo xCin85
    *** cells: HEK293T in BMS
    *** source: 11894095-Fig-2c
  *** xEndA1[tAb] copptby[WB] xCbl[Ab] is detectable
    *** cells: HEK293T<xCin85> in BMS
    *** reqs: xCin85 [omission]
    *** source: 11894095-Fig-2a
  *** xEndA1[tAb] copptby[WB] xCin85[tAb] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: Egf (5 min) [stim]
    *** unaffected by: xEndA1 [addition]
    *** source: 11894095-Fig-2b
  *** xEndA3[tAb] copptby[WB] xCbl[tAb] is detectable
    *** cells: HEK293T<xCbl><xCin85><xEndA3> in BMS
    *** inhibited by: xCin85(mnr)"PCC" [substitution]
    *** source: 11894096-Fig-1c
  *** xEndA3[tAb] copptby[WB] xCin85[tAb] is detectable
    *** cells: HEK293T<xCbl><xCin85><xEndA3> in BMS
    *** source: 11894096-Fig-1c
  *** xEng[Ab] copptby[WB] xAcvR1b[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 10187774(D)
  *** xEng[Ab] copptby[WB] xAcvRl1[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 10187774(D)
  *** xEng[Ab] copptby[WB] xTgfbR1[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 10187774(D)
  *** rEno1[MS] cleavage[WB] is increased by rCasp1
    *** cells: none
    *** source: 17959595(D)
  *** rEno1[MS] cleavage[WB] is unchanged by rCasp3
    *** cells: none
    *** source: 17959595(D)
  *** Eomes-gene mRNA[RTPCR] is detectable
    *** cells: mSpCD4TCs in BMS "pretreated with anti-Cd3 + anti-Cd28 + IL12 for 5 days"
    *** does not req: Stat6 [KO]
    *** does not req: Tbet [KO]
    *** source: 19324016-Fig-3c
*** Ep300--
  *** rEp300(1-743)[35S] boundby[WB] rElk1(205-428)[GST] is detectable
    *** cells: none
    *** inhibited by: rEp300(del(242-1737)) [substitution]
    *** inhibited by: rEp300(634-1922) [substitution]
    *** inhibited by: rEp300(1514-1922) [substitution]
    *** source: 12514134-Fig-2c
  *** rEp300(1-743)[35S] boundby[WB] rElk1(310-428)[GST] is detectable
    *** cells: none
    *** inhibited by: rEp300(del(242-1737)) [substitution]
    *** inhibited by: rEp300(634-1922) [substitution]
    *** inhibited by: rEp300(1514-1922) [substitution]
    *** source: 12514134-Fig-2c
  *** rEp300(1-743)[35S] boundby[WB] rElk1(349-428)[GST] is detectable
    *** cells: none
    *** inhibited by: rEp300(del(242-1737)) [substitution]
    *** inhibited by: rEp300(634-1922) [substitution]
    *** inhibited by: rEp300(1514-1922) [substitution]
    *** source: 12514134-Fig-2c
  *** rEp300(1-743)[35S] boundby[WB] rElk1[GST] is detectable
    *** cells: none
    *** inhibited by: rEp300(del(242-1737)) [substitution]
    *** inhibited by: rEp300(634-1922) [substitution]
    *** inhibited by: rEp300(1514-1922) [substitution]
    *** source: 12514134-Fig-3b
  *** rEp300(1514-1922)[35S] boundby[WB] rElk1(310-428){phos}[GST] is detectable
    *** cells: none
    *** comment: rElk1 was phosphorylated by rErk2{act}
    *** inhibited by: rElk1((310-428)/S383A/S389A){phos} [substitution]
    *** source: 12514134-Fig-3b
  *** rEp300(1514-1922)[35S] boundby[WB] rElk1{phos}[GST] is detectable
    *** cells: none
    *** comment: rElk1 was phosphorylated by rErk2{act}
    *** inhibited by: rElk1 [substitution]
    *** source: 12514134-Fig-3b
  *** Ep300[Ab] boundto(Cdkn1a-gene)[ChIP] is detectable
    *** cells: HCT116 in BMS "treated with etoposide"
    *** partially reqs: Pin1 [RNAi]
    *** source: 17906639-Fig-5d
  *** Ep300[Ab] boundto(Cdkn1a-gene)[ChIP] is detectable
    *** cells: U2OS in BMS "treated with Etoposide for 12 hr"
    *** partially reqs: Pin1 [RNAi]
    *** source: 17906639-Fig-S5b
  *** Ep300[Ab] boundto(Cdkn1b-gene)[ChIP] is detectable
    *** cells: HELA in BMS
    *** reqs: Arrb1 [RNAi]
    *** enhanced by: xArrb1 [addition]
    *** unaffected by: xArrb1(Q394L) [addition]
    *** source: 16325578-Fig-4a
  *** Ep300[Ab] boundto(Cdkn1b-gene)[ChIP] is increased itpo xArrb1
    *** cells: mEFs<Arrb1~null><Arrb2~null> in BMS
    *** inhibited by: xArrb1(Q394L) [substitution]
    *** source: 16325578-Fig-3a
  *** Ep300[Ab] boundto(Fos-gene)[ChIP] is detectable
    *** cells: HELA in BMS
    *** reqs: Arrb1 [RNAi]
    *** enhanced by: xArrb1 [addition]
    *** unaffected by: xArrb1(Q394L) [addition]
    *** source: 16325578-Fig-4a
  *** Ep300[Ab] boundto(Fos-gene)[ChIP] is increased itpo xArrb1
    *** cells: mEFs<Arrb1~null><Arrb2~null> in BMS
    *** inhibited by: xArrb1(Q394L) [substitution]
    *** source: 16325578-Fig-3a
  *** Ep300[Ab] boundto(Jun-gene)[ChIP] is detectable
    *** cells: HELA in BMS
    *** does not req: Arrb1 [RNAi]
    *** unaffected by: xArrb1 [addition]
    *** unaffected by: xArrb1(Q394L) [addition]
    *** source: 16325578-Fig-4a
  *** Ep300[Ab] boundto(Jun-gene)[ChIP] is unchanged itpo xArrb1
    *** cells: mEFs<Arrb1~null><Arrb2~null> in BMS
    *** unaffected by: xArrb1(Q394L) [substitution]
    *** source: 16325578-Fig-3a
  *** Ep300[Ab] copptby[WB] Arrb1[Ab] is detectable
    *** cells: HELA in BMS "nuclear-extracts"
    *** source: 16325578-Fig-4c
  *** Ep300[Ab] copptby[WB] Mdm2[Ab] is detectable
    *** cells: NIH3T3<xErbb2> in BMS
    *** source: 11715018-Fig-7a
  *** Ep300[Ab] copptby[WB] Mdm2[Ab] is undetectable
    *** cells: NIH3T3<xAkt1(mnr)"DN"> in BMS
    *** source: 11715018-Fig-7a
  *** Ep300[Ab] copptby[WB] xMdm2[Ab] is detectable
    *** cells: mEFs<Tp53~null><Mdm2~null><xMdm2> in BMS
    *** enhanced by: xMdm2(S166D) [substitution]
    *** enhanced by: xMdm2(S186D) [substitution]
    *** enhanced by: xMdm2(S166D/S186D) [substitution]
    *** source: 11715018-Fig-7b
  *** xEp300[Gal4-DBD] Gal4-reporter[Luc] is increased itao Hdac3 [RNAi]
    *** cells: HEK293 in BMS
    *** source: 14992729-Fig-2d
  *** xEp300[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xPias2a
    *** cells: HEK293 in BMLS
    *** partially inhibited by: xEp300(mnr)"delR" [substitution]
    *** source: 15920481-Fig-7a
  *** xEp300[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xPias2a
    *** cells: HEK293 in BMLS
    *** partially inhibited by: xPias2a(103-572) [substitution]
    *** partially inhibited by: xPias2a(del(467-487)) [substitution]
    *** unaffected by: xPias2a(W383A) [substitution]
    *** source: 15920481-Fig-7b
  *** xEp300[Gal4-DBD] Gal4-reporter[Luc] is unchanged itao Hdac1 [RNAi]
    *** cells: HEK293 in BMS
    *** source: 14992729-Fig-2d
  *** xEp300[Gal4-DBD] Gal4-reporter[Luc] is unchanged itao Hdac2 [RNAi]
    *** cells: HEK293 in BMS
    *** source: 14992729-Fig-2d
*** Epha4--
  *** xEpha4[Ab] copptby[WB] xNgef[Ab] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xEpha4(V635M)"KD" [substitution]
    *** source: 11336673-Fig-3a
  *** Eps8[Ab] copptby[WB] Actin[Ab] is detectable
    *** cells: mEFs in BMS
    *** source: 11524436(D)
  *** Eps8[Ab] copptby[WB] Pik3c2a[Ab] is undetectable
    *** cells: A431 in BMLS "Triton-Soluble fraction"
    *** unaffected by: Egf (10 min) [stim]
    *** source: 16775008-Fig-2c
  *** Eps8[Ab] copptby[WB] Pik3c2b[Ab] is detectable
    *** cells: A431 in BMLS "Triton-Soluble fraction"
    *** unaffected by: Egf (10 min) [stim]
    *** source: 16775008-Fig-2c
  *** Eps8[Ab] copptby[WB] xPik3c2b[tAb] is detectable
    *** cells: A431 in BMLS "Triton-Insoluble fraction"
    *** unaffected by: Egf (5,30,60,120,240,360,480 min) [stim]
    *** comment: This contradicts the data found in Fig-1a
    *** source: 16775008-Fig-2a
  *** xEps8[Ab] copptby[WB] xSos1[Ab] is detectable
    *** cells: COS7<xAbi1> in BMS
    *** reqs: xAbi1 [omission]
    *** inhibited by: xEps8(del(SH3)) [substitution]
    *** source: 10499589-Fig-4c
  *** xEps8[Ab] copptby[WB] xSos1[Ab] is detectable
    *** cells: mEFs<Shc1p66~null><xShc1p66><xAbi1> in BMS
    *** reqs: xShc1p66 [omission]
    *** source: 16520382-Fig-2a
  *** xEps8[Ab] copptby[WB] xSos1[Ab] is detectable
    *** cells: mEFs<xAbi1> in BMS
    *** reqs: Shc1p66 [KO]
    *** source: 16520382-Fig-2a
  *** xEps8[Ab] copptby[WB] xSos1[tAb] is detectable
    *** cells: COS7<xAbi1> in BMS
    *** comment: coppt contains xAbi1
    *** source: 11777939-Fig-7a
  *** xEps8[Ab]IP IVGefA(Hras)[3H-GDP] is undetectable
    *** cells: COS7<xAbi1><xSos1> in BMS
    *** source: 11777939-Fig-7b
  *** xEps8[Ab]IP IVGefA(Rac1)[3H-GDP] is increased itpo (xAbi1 + xSos1)
    *** cells: COS7 in BMS
    *** reqs: xSos1 [omission]
    *** inhibited by: xEps8(del(SH3)) [substitution]
    *** source: 10499589-Fig-4d
  *** xEps8[Ab]IP IVGefA(Rac1)[3H-GDP] is unchanged itpo xAbi1
    *** cells: COS7 in BMS
    *** source: 10499589-Fig-4d
  *** xEps8[tAb]IP IVGefA(Rac1)[3H-GDP] is detectable
    *** cells: HEK293T<xAbi1><xSos1> in BMS
    *** reqs: xAbi1 [omission]
    *** source: 14565974-Fig-3b
  *** xEps8[tAb]IP IVGefA(Rac1)[3H-GDP] is detectable
    *** cells: HEK293T<xSos1><xAbi1> in BMS
    *** inhibited by: xAbi1(Y407F) [substitution]
    *** source: 12515821-Fig-3b
  *** xEps8[tAb]IP IVGefA(Rac1)[3H-GDP] is detectable
    *** cells: HEK293T<xSos1><xAbi1> in BMS
    *** inhibited by: xSos1(mnr)"DH-domain-mut" [substitution]
    *** source: 12515821-Fig-3b
  *** xEps8l1[tAb]IP IVGefA(Rac1)[3H-GDP] is detectable
    *** cells: HEK293T<xAbi1><xSos1> in BMS
    *** reqs: xAbi1 [omission]
    *** source: 14565974-Fig-3b
  *** xEps8l2[tAb]IP IVGefA(Rac1)[3H-GDP] is detectable
    *** cells: HEK293T<xAbi1><xSos1> in BMS
    *** reqs: xAbi1 [omission]
    *** source: 14565974-Fig-3b
  *** xEps8l3[tAb]IP IVGefA(Rac1)[3H-GDP] is undetectable
    *** cells: HEK293T<xAbi1><xSos1> in BMS
    *** source: 14565974-Fig-3b
  *** xEps15[tAb] copptby[WB] xEgfR[tAb] is detectable
    *** cells: HEK293<xEps15><xEgfR> in BMLS "treated with Egf for 8 min"
    *** inhibited by: xEps15(del(361-643))"dII" [substitution]
    *** unaffected by: xEps15(813-896)"dIV" [substitution]
    *** source: 19109251-Fig-3e
  *** xEps15[tAb] copptby[WB] xGrb2[tAb] is detectable
    *** cells: HEK293<xEps15><xGrb2> in BMS
    *** unaffected by: xHgfR [addition]
    *** source: 19109251-Fig-4b
  *** xEps15[tAb] copptby[WB] xHgfR[tAb] is detectable
    *** cells: HEK293<xEps15><xHgfR> in BMS
    *** inhibited by: xEps15(del(361-643))"dII" [substitution]
    *** inhibited by: xEps15(648-896)"dIII" [substitution]
    *** unaffected by: xEps15(350-643)"II" [substitution]
    *** partially inhibited by: xEps15(643-813)"III" [substitution]
    *** unaffected by: xEps15(350-813)"II/III" [substitution]
    *** source: 19109251-Fig-3b
  *** xEps15[tAb] copptby[WB] xHgfR[tAb] is detectable
    *** cells: HEK293<xEps15><xHgfR> in BMS
    *** unaffected by: xEps15(360-896)"dI" [substitution]
    *** inhibited by: xEps15(del(361-643))"dII" [substitution]
    *** inhibited by: xEps15(648-896)"dIII" [substitution]
    *** unaffected by: xEps15(813-896)"dIV" [substitution]
    *** unaffected by: xEps15(Y850F) [substitution]
    *** source: 19109251-Fig-3a
  *** xEps15[tAb] copptby[WB] xHgfR[tAb] is detectable
    *** cells: HEK293<xEps15><xHgfR> in BMS
    *** unaffected by: xHgfR(Y1003F) [substitution]
    *** source: 19109251-Fig-3d
  *** xEps15[tAb] snaggedby[WB] rGrb2[GST] is detectable
    *** cells: HEK293<xEps15> in BMS
    *** partially inhibited by: xEps15(P770A) [substitution]
    *** source: 19109251-Fig-4f
  *** xEps15[tAb] Yphos[pYAb] is increased itpo xHgfR
    *** cells: HEK293<xEps15> in BMS
    *** inhibited by: xEps15(Y805F) [substitution]
    *** source: 19109251-Fig-2f
  *** xEps15[tAb] Yphos[pYAb] is increased itpo xHgfR
    *** cells: HEK293<xEps15> in BMS
    *** inhibited by: xHgfR(K110A) [substitution]
    *** source: 19109251-Fig-2f
  *** xEps15[tAb] Yphos[pYAb] is increased itpo xHgfR
    *** cells: HEK293<xEps15> in BMS
    *** source: 19109251-Fig-2e
  *** Erbb2[Ab] copptby[WB] Grb2[Ab] is detectable
    *** cells: SKBR3 in BMLS
    *** inhibited by: xJak2(del(Cterm))"KD" [addition]
    *** source: 10938266(D)
  *** Erbb2[Ab] copptby[WB] Jak2[Ab] is detectable
    *** cells: A431 in BMLS
    *** unaffected by: Egf (10 min) [stim]
    *** inhibited by: Hbegf (10 min) [stim]
    *** inhibited by: Btc (10 min) [stim]
    *** unaffected by: Nrg1 (10 min) [stim]
    *** source: 10358079-Fig-7b
  *** xErbb2[Ab] copptby[WB] Jak2[Ab] is detectable
    *** cells: NIH3T3<xErbb2><xErbb4> in BMLS
    *** unaffected by: Nrg1 (10 min) [stim]
    *** source: 10358079-Fig-7a
  *** Erbb2[Ab]IP Yphos[pYAb] is detectable
    *** cells: SKBR3 in BMS "quiescent"
    *** inhibited by: xJak2(del(Cterm))"KD" [addition]
    *** source: 10938266(D)
  *** xErbb4[125I] boundby[Xlink] rHbegf[125I] is detectable
    *** cells: NIH3T3<xErbb4> in BMS
    *** source: 9135143-Fig-2
  *** xErbb4[125I] boundby[Xlink] rNrg1[125I] is detectable
    *** cells: NIH3T3<xErbb4> in BMS
    *** source: 9135143-Fig-2
  *** xErbin[Ab] copptby[WB] Pak2[Ab] is detectable
    *** cells: AKR2B<xErbin> in BMLS
    *** reqs: Merlin [RNAi]
    *** source: 19289088-Fig-4a
  *** Erbin[Ab] snaggedby[WB] rMerlin[GST] is detectable
    *** cells: MV1LU in BMLS
    *** source: 19289088-Fig-2b
  *** Erbin[Ab] snaggedby[WB] rMerlin[GST] is undetectable
    *** cells: AKR2B in BMLS
    *** source: 19289088-Fig-2b
  *** xErc1[tAb] copptby[WB] xIkba[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15218148-Fig-4b
  *** xErc1[tAb]IP ubiq[tUbAb] is increased itpo xTraf2
    *** cells: HEK293<xErc1><xUbiq><xXiap> in BMS
    *** inhibited by: xTraf2(mnr)"delRing" [substitution]
    *** source: 20932476-Fig-S7c
  *** rErg[35S] boundby[WB] rEts2[GST] is detectable
    *** cells: none
    *** enhanced by: xFos [addition]
    *** source: 9334186-Fig-1a
*** Erk?--
  *** xErk?[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: CHO<xInsR> in BMLS
    *** inhibited by: xDok1 [addition]
    *** unaffected by: rDok1(Y362F/Y398F) [addition]
    *** source: 11551902-Fig-7a
  *** xErk?[tAb]IP IVKA(Atf2)(T71)[phosAb] is unchanged itpo xRgl2(mnr)"CAAX"
    *** cells: NIH3T3<xInsR> in BMLS
    *** source: 12110590-Fig-5e
  *** xErk?[tAb]IP IVKA(Elk1)[32P-ATP] is detectable
    *** cells: HEK293<xBraf><xErk?> in BMLS
    *** unaffected by: xBraf(S364A) [substitution]
    *** enhanced by: xBraf(S428A/T439A) [substitution]
    *** enhanced by: xBraf(S364A/S428A/T439A) [substitution]
    *** source: 10869359-Fig-3
  *** xErk?[tAb]IP IVKA(Elk1)[32P-ATP] is increased itpo xHras(G12V)"CA"
    *** cells: HEK293 in BMS
    *** source: 11447113-Fig-5c
  *** xErk?[tAb]IP IVKA(Elk1)[32P-ATP] is increased itpo xKras(G12V)"CA"
    *** cells: HEK293<xErk?> in BMLS
    *** source: 10869359-Fig-4b
  *** xErk?[tAb]IP IVKA(Elk1)[32P-ATP] is increased itpo xRaf1
    *** cells: HEK293 in BMS
    *** enhanced by: xRaf1(T491E/S494D) [substitution]
    *** enhanced by: xRaf1(T491E/S494D/S338D/S341D) [substitution]
    *** source: 11447113-Fig-5c
  *** xErk?[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xPlce1
    *** cells: TSA201 in BMS
    *** enhanced by: xPlce1(H1144L)"CIA" [substitution]
    *** source: 11022047-Fig-5a
  *** xErk?[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xPlce1
    *** cells: TSA201 in BMS
    *** unaffected by: xPlce1(1-600)"Gef-domain" [substitution]
    *** source: 11022047-Fig-6a
  *** xErk?[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xRasGrf2
    *** cells: TSA201 in BMS
    *** source: 11022047-Fig-5a
  *** xErk?[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xArhGef7
    *** cells: NIH3T3 in BMS
    *** source: 11309380-Fig-1a
  *** xErk?[tAb]IP phos(TEY)[phosAb] is increased itpo xHras(G12V)
    *** cells: C2C12<xErk?> in BMS
    *** inhibited by: xSpred1 [addition]
    *** source: 15239952-Fig-4b
  *** xErk?[tAb]IP phos(TEY)[phosAb] is increased itpo xHras(G12V)
    *** cells: C2C12<xErk?> in BMS
    *** unaffected by: xIL17Rd [addition]
    *** source: 15239952-Fig-4b
  *** xErk?[tAb]IP phos(TEY)[phosAb] is increased itpo xMek?(mnr)"SDSE"
    *** cells: C2C12<xErk?> in BMS
    *** unaffected by: xIL17Rd [addition]
    *** source: 15239952-Fig-4c
  *** xErk?[tAb]IP phos(TEY)[phosAb] is increased itpo xMek?(mnr)"SDSE"
    *** cells: C2C12<xErk?> in BMS
    *** unaffected by: xSpred1 [addition]
    *** source: 15239952-Fig-4c
  *** xErk?[XFP] locatedin(nucleus-cytoplasm)[IHC] is detectable
    *** cells: HELA<xErk?> in BMS
    *** source: 15239952-Fig-5b
  *** rErk1 IVKA(MBP)[32P-ATP] is increased by rMlk3
    *** cells: none
    *** comment: rMek1 was included in the reaction mix
    *** inhibited by: rMlk3(K144A)"KD" [substitution]
    *** source: 12738796-Fig-2b
  *** rErk1 IVKA(MBP)[32P-ATP] is unchanged by rMkk3
    *** cells: none
    *** source: 8226933-Fig-1a
  *** rErk1 IVKA(MBP)[32P-ATP] is unchanged by rMkk4
    *** cells: none
    *** source: 9384583-Fig-1b
  *** rErk1 IVKA(MBP)[32P-ATP] is unchanged by rMkk6
    *** cells: none
    *** source: 9384583-Fig-1b
  *** rErk1 IVKA(MBP)[32P-ATP] is unchanged by rMkk7
    *** cells: none
    *** source: 9384583-Fig-1b
*** Erk1--
  *** rErk1(K52R)[32P] phos[32P-ATP] is increased by xMlk3[tAb]IP
    *** cells: none
    *** comment: rMek1 is present in the reaction mix
    *** comment: xMlk3 IP is from HEK293 cells
    *** inhibited by: xMlk3(K144A)"KD" [substitution]
    *** source: 10232608-Fig-5c
  *** rErk1[32P] phos[32P-ATP] is increased by rMlk3
    *** cells: none
    *** comment: rMek1 was included in the reaction mix
    *** inhibited by: rMlk3(K144A)"KD" [substitution]
    *** source: 12738796-Fig-2b
  *** rErk1[32P] phos[32P-ATP] is increased by rMlk3
    *** cells: none
    *** comment: rMek1 was included in the reaction mix
    *** source: 12738796-Fig-2c
  *** rErk1[35S] boundby[WB] rPea15[GST] is detectable
    *** cells: none
    *** unaffected by: xErk1(T192A) [substitution]
    *** source: 11702783-Fig-6b
  *** rErk1[Ab] boundby[WB] rIqGap1[GST] is detectable
    *** cells: none
    *** unaffected by: rMek1 [addition]
    *** source: 16135787-Fig-9a
  *** rErk1[Ab] boundby[WB] rIqGap1[GST] is detectable
    *** cells: none
    *** unaffected by: rMek2 [addition]
    *** source: 16135787-Fig-9b
  *** rErk1[Ab] boundby[WB] rPxn(1-323)[GST] is detectable
    *** cells: none
    *** enhanced by: rPxn(1-323){phos} [substitution]
    *** comment: rPxn{phos} was phosed by rSrc{act}
    *** source: 14636584-Fig-3d
  *** rErk1[Ab] boundby[WB] rPxn(1-323)[GST] is detectable
    *** cells: none
    *** inhibited by: rErk1{phos} [substitution]
    *** comment: rErk1{phos} was phosed by Mek1{act}
    *** source: 14636584-Fig-2c
  *** rErk1[Ab] boundby[WB] rPxn(1-323)[GST] is detectable
    *** cells: none
    *** inhibited by: rErk1{phos} [substitution]
    *** comment: rErk1{phos} was phosed by rMek1{act}
    *** source: 14636584-Fig-3e
  *** rErk1[Ab] boundby[WB] rPxn(1-323){phos}[GST] is detectable
    *** cells: none
    *** comment: rPxn{phos} was phosed by rSrc{act}
    *** comment: inhibited by addition of EEEHVpYSFPNKQ peptide
    *** comment: partially inhibited by addition of EEEHVYSFPNKQ peptide
    *** source: 14636584-Fig-4c
  *** rErk1[Ab] boundby[WB] rPxn(1-323){phos}[GST] is detectable
    *** cells: none
    *** comment: rPxn{phos} was phosed by rSrc{act}
    *** inhibited by: rPxn((1-323)/Y118A) [substitution]
    *** source: 14636584-Fig-4a
  *** rErk1[Ab] boundby[WB] rPxn(1-323){phos}[GST] is detectable
    *** cells: none
    *** comment: rPxn{phos} was phosed by Src
    *** inhibited by: rPxn(1-323){unphos} [substitution]
    *** source: 14636584-Fig-3d
  *** xErk1[Ab] copptby[WB] Mekk1[Ab] is detectable
    *** cells: HEK293T in BMLS
    *** enhanced by: Sorbitol (1 hr) [stim]
    *** source: 12049732-Fig-2b
  *** Erk1[Ab] copptby[WB] xMsk1[tAb] is detectable
    *** cells: HEK293 in BMLS
    *** unaffected by: UV (30 min) [stim]
    *** unaffected by: PMA (10 min) [stim]
    *** inhibited by: xMsk1(L740A)"Mapk-docking-mut" [substitution]
    *** inhibited by: xMsk1(R743A/R744A)"Mapk-docking-mut" [substitution]
    *** unaffected by: xMsk1(S750A/S752A) [substitution]
    *** unaffected by: xMsk1(S758A) [substitution]
    *** source: 15568999-Fig-8
  *** Erk1[Ab] locatedin(nucleus-cytoplasm)[IHC] is detectable
    *** cells: CCL39 in BMLS
    *** source: 8392845-Fig-2a
  *** xErk1[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: CCL39<xErk1> in BMS
    *** inhibited by: xDusp6(C293S) [addition]
    *** source: 9927426-Fig-2a
  *** Erk1[Ab] snaggedby[WB] Mapkapk2[GST] is undetectable
    *** cells: HEK293 in BMS
    *** source: 10347227-Fig-6a
  *** Erk1[Ab]IP IVKA(EgfR)[32P-ATP] is unchanged itpo xMekk4(CatDom)"CA"
    *** cells: HEK293 in BMS
    *** source: 9079650-Fig-5
  *** xErk1[Ab]IP IVKA(MBP)[32P-ATP] is unchanged itpo xMekk1
    *** cells: NIH3T3<xErk1> in BMLS
    *** source: 8548291-Fig-6e
  *** xErk1[Ab]IP ubiq[UbAb] is increased itpo xMekk1
    *** cells: HEK293T in BMLS
    *** inhibited by: xMekk1(C433A/C478A) [substitution]
    *** source: 12049732-Fig-4a
  *** rErk1[His] IVKA(MBP)[32P-ATP] is unchanged by rMkk6
    *** cells: none
    *** source: 8663074-Fig-2
  *** xErk1[phosAb] phos(TEY)[phosAb] is increased itpo xMlk3
    *** cells: COS7 in BMLS
    *** unaffected by: CalyculinA [addition]
    *** inhibited by: xMlk3(K144A)"KD" [substitution]
    *** source: 12738796-Fig-1b
  *** xErk1[phosAb] phos(TEY)[phosAb] is increased itpo xRipk1
    *** cells: mEFs<Ripk1~null> in BMS
    *** inhibited by: xRipk1(K45A)"KD" [substitution]
    *** source: 12776182-Fig-3a
  *** xErk1[phosAb] phos(TEY)[phosAb] is unchanged itpo xRheb
    *** cells: HELA<xErk1> in BMLS
    *** source: 12820960-Fig-3a
  *** xErk1[phosAb] phos(TEY)[phosAb] is unchanged itpo xTraf2
    *** cells: HEK293 in BMS
    *** source: 16291755-Fig-3d
  *** xErk1[tAb] copptby[WB] xGadd45b[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 14743220-Fig-1a
  *** xErk1[tAb] copptby[WB] xLamtor3[tAb] is detectable
    *** cells: CCL39 in BMS
    *** source: 9733512-Fig-3a
  *** xErk1[tAb] IVKA(MBP)[32P-ATP] is increased itpo xRaf1
    *** cells: NIH3T3<xErk1> in BMS
    *** enhanced by: xWdr83 [addition]
    *** source: 15118098-Fig-5a
  *** xErk1[tAb] locatedin(nucleus)[IHC] is detectable
    *** cells: CCL39<xErk1> in BMLS
    *** partially inhibited by: xErk1(T192A) [substitution]
    *** partially inhibited by: xErk1(T192E/Y194E) [substitution]
    *** inhibited by: xErk1(1-239) [substitution]
    *** source: 8392845-Fig-5a
  *** xErk1[tAb]IP IVKA(auto)[32P-ATP] is increased itpo xRaf1(del(66-303))"CA"
    *** cells: COS7 in BMLS
    *** source: 12738796-Fig-3b
  *** xErk1[tAb]IP IVKA(auto)[32P-ATP] is unchanged itpo xMlk3
    *** cells: COS7 in BMLS
    *** source: 12738796-Fig-3b
  *** xErk1[tAb]IP IVKA(Elk1)[32P-ATP] is increased itpo xBraf
    *** cells: COS1 in BMLS
    *** inhibited by: xBraf(T598A/S601A) [substitution]
    *** enhanced by: xBraf(T598E/S601D) [substitution]
    *** source: 11032810-Fig-4a
  *** xErk1[tAb]IP IVKA(Elk1)[32P-ATP] is increased itpo xBraf
    *** cells: HEK293 in BMS
    *** enhanced by: xBraf(T598E/S601D) [substitution]
    *** unaffected by: xBraf(S364A) [substitution]
    *** unaffected by: xBraf(S428A/S439A) [substitution]
    *** unaffected by: xBraf(S364A/S428A/S439A) [substitution]
    *** source: 11410590-Fig-2b
  *** xErk1[tAb]IP IVKA(Elk1)[32P-ATP] is increased itpo xBraf
    *** cells: HEK293 in BMS
    *** inhibited by: xSgk1(S422D)"CA" [addition] no-bkg-control
    *** source: 11410590-Fig-2b
  *** xErk1[tAb]IP IVKA(Elk1)[32P-ATP] is increased itpo xBraf(mnr)"CA"
    *** cells: HEK293 in BMLS
    *** inhibited by: xShoc2 [addition]
    *** source: 10783161-Fig-2b
  *** xErk1[tAb]IP IVKA(Elk1)[32P-ATP] is increased itpo xBraf(mnr)"CA"
    *** cells: HEK293 in BMLS
    *** source: 10783161-Fig-2b
  *** xErk1[tAb]IP IVKA(Elk1)[32P-ATP] is increased itpo xHras(G12V)"CA"
    *** cells: COS1 in BMLS
    *** source: 11032810-Fig-4a
  *** xErk1[tAb]IP IVKA(Elk1)[32P-ATP] is increased itpo xHras(G12V)"CA"
    *** cells: HEK293 in BMLS
    *** enhanced by: xShoc2 [addition]
    *** source: 10783161-Fig-1a,1b
  *** xErk1[tAb]IP IVKA(Elk1)[32P-ATP] is increased itpo xHras(G12V)"CA"
    *** cells: HEK293 in BMLS
    *** source: 10783161-Fig-1a,1b
  *** xErk1[tAb]IP IVKA(Elk1)[32P-ATP] is increased itpo xHras(Q61L)"CA"
    *** cells: HC11 in BMS
    *** partially inhibited by: xPkce(K436R)"DN" [addition]
    *** source: 11551901-Fig-3a
  *** xErk1[tAb]IP IVKA(Elk1)[32P-ATP] is increased itpo xHras(Q61L)"CA"
    *** cells: HC11 in BMS
    *** partially inhibited by: xPkcz(K275W)"DN" [addition]
    *** source: 11551901-Fig-3a
  *** xErk1[tAb]IP IVKA(Elk1)[32P-ATP] is increased itpo xHras(Q61L)"CA"
    *** cells: HC11 in BMS
    *** source: 11551901-Fig-3a
  *** xErk1[tAb]IP IVKA(Elk1)[32P-ATP] is increased itpo xHras(Q61L)"CA"
    *** cells: HC11 in BMS
    *** source: 11551901-Fig-3a
  *** xErk1[tAb]IP IVKA(Elk1)[32P-ATP] is increased itpo xHras(Q61L)"CA"
    *** cells: HC11 in BMS
    *** source: 11551901-Fig-3a
  *** xErk1[tAb]IP IVKA(Elk1)[32P-ATP] is increased itpo xHras(Q61L)"CA"
    *** cells: HC11 in BMS
    *** unaffected by: xPkci(K275W)"DN" [addition]
    *** source: 11551901-Fig-3a
  *** xErk1[tAb]IP IVKA(Elk1)[32P-ATP] is increased itpo xKras(G12V)"CA"
    *** cells: HEK293 in BMLS
    *** enhanced by: xShoc2 [addition]
    *** source: 10783161-Fig-1a,1b
  *** xErk1[tAb]IP IVKA(Elk1)[32P-ATP] is increased itpo xNras(G12V)"CA"
    *** cells: HEK293 in BMLS
    *** enhanced by: xShoc2 [addition]
    *** source: 10783161-Fig-1a,1b
  *** xErk1[tAb]IP IVKA(Elk1)[32P-ATP] is increased itpo xRaf1(del(66-303))"CA"
    *** cells: HC11 in BMS
    *** partially inhibited by: xPkce(K436R)"KD" [addition]
    *** source: 11551901-Fig-3b
  *** xErk1[tAb]IP IVKA(Elk1)[32P-ATP] is increased itpo xRaf1(del(66-303))"CA"
    *** cells: HC11 in BMS
    *** partially inhibited by: xPkcz(K275W)"KD" [addition]
    *** source: 11551901-Fig-3b
  *** xErk1[tAb]IP IVKA(Elk1)[32P-ATP] is increased itpo xRaf1(mnr)"vRaf"
    *** cells: HEK293 in BMLS
    *** enhanced by: xShoc2 [addition]
    *** source: 10783161-Fig-2b
  *** xErk1[tAb]IP IVKA(Elk1)[32P-ATP] is unchanged itpo xShoc2
    *** cells: HEK293 in BMLS
    *** source: 10783161-Fig-1a
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is decreased itpo xMlk3(K144A)"KD"
    *** cells: COS7 in BMLS
    *** inhibited by: xMlk3(WT) [substitution]
    *** source: 12738796-Fig-1a
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xHras(G12V)"CA"
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1d
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xJak1
    *** cells: HEK293<xLepRb> in BMLS
    *** source: 9405487(D)
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xJak2
    *** cells: HEK293<xLepRb> in BMLS
    *** source: 9405487(D)
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xKras(G12V)"CA"
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1d
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xMekk1
    *** cells: HEK293T<xErk1> in BMS
    *** source: 10521462-Fig-5b
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xMkk7
    *** cells: COS7 in BMS
    *** source: 9384583-Fig-1a
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xMlk3
    *** cells: COS7 in BMLS
    *** unaffected by: CalyculinA [addition]
    *** source: 12738796-Fig-1b
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xMlk3
    *** cells: COS7 in BMLS
    *** unaffected by: xMkk4(S220A/T224L)"DN" [addition]
    *** source: 12738796-Fig-3a
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xMlk3
    *** cells: HEK293 in BMS
    *** enhanced by: xMek1 [addition]
    *** inhibited by: xMlk3(K144A)"KD" [addition]
    *** source: 10232608-Fig-4c
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xMlk3
    *** cells: HEK293 in BMS
    *** inhibited by: xMlk3(K144A)"KD" [addition]
    *** source: 10232608-Fig-4b
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xMlk3
    *** cells: HEK293 in BMS
    *** source: 10232608-Fig-4c
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xMlk3
    *** cells: HEK293 in BMS
    *** unaffected by: xRaf1(del(66-303))"CA" [substitution]
    *** unaffected by: xRaf1(mnr)"DN" [substitution]
    *** source: 10232608-Fig-4b
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xMras(Q71L)"CA"
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1d
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xNras(G12V)"CA"
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1d
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xRaf1
    *** cells: HEK293 in BMS
    *** enhanced by: xRaf1(del(66-303))"CA" [substitution]
    *** inhibited by: xRaf1(mnr)"DN" [substitution]
    *** source: 10232608-Fig-4b
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xRaf1(del(66-303))"CA"
    *** cells: COS in BMS
    *** source: 8702571-Fig-1c
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xRaf1(del(66-303))"CA"
    *** cells: COS7 in BMLS
    *** source: 12738796-Fig-3b
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xRaf1(del(66-303))"CA"
    *** cells: HEK293 in BMS
    *** partially inhibited by: xMlk3(K144A)"KD" [addition]
    *** source: 10232608-Fig-4c
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xRaf1(del(66-303))"CA"
    *** cells: HEK293 in BMS
    *** source: 10232608-Fig-4c
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xRaf1(del(66-303))"CA"
    *** cells: HEK293 in BMS
    *** unaffected by: xMek1 [addition]
    *** source: 10232608-Fig-4c
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xRasGrf2
    *** cells: HEK293T in BMLS
    *** enhanced by: Ionomycin [addition]
    *** bkg inhibited by: xHras(S17N)"DN" [addition]
    *** source: 9032266-Fig-6
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xRipk1
    *** cells: mEFs<Ripk1~null> in BMS
    *** inhibited by: xRipk1(K45A)"KD" [substitution]
    *** source: 12776182-Fig-3b
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xRit1(Q79L)"CA"
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1d
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xRras2(G23V)"CA"
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1d
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xLamtor3
    *** cells: NIH3T3 in BMLS
    *** source: 9733512-Fig-4
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xMkk4
    *** cells: COS7 in BMS
    *** source: 9384583-Fig-1a
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xMkk6
    *** cells: COS7 in BMS
    *** source: 9384583-Fig-1a
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xMlk3
    *** cells: COS in BMS
    *** source: 8702571-Fig-1c
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xMlk3
    *** cells: COS7 in BMLS
    *** source: 12738796-Fig-1a
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xMlk3(K144A)"KD"
    *** cells: COS7 in BMLS
    *** source: 12738796-Fig-1b
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xRap1a(G12V)"CA"
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1d
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xRap2a(G12V)"CA"
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1d
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xRheb(Q64L)"CA"
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1d
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xRin1(A78L)"CA"
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1d
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xRras(G38V)"CA"
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1d
  *** xErk1[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xTnik
    *** cells: HEK293T<xErk1> in BMS
    *** source: 10521462-Fig-5b
  *** xErk1[tAb]IP phos(TEY)[phosAb] is decreased itpo xMlk3
    *** cells: COS7 in BMLS "treated with Egf for 10 min"
    *** unaffected by: xJun [addition]
    *** inhibited by: xJun(mnr)"Tam67" [addition]
    *** inhibited by: xJun(mnr)"DBM3" [addition]
    *** source: 12738796-Fig-5a
  *** xErk1[tAb]IP phos(TEY)[phosAb] is increased itpo xBraf(V599E)"CA"
    *** cells: COS7 in BMLS
    *** unaffected by: xBraf(V99E/S578A) [substitution]
    *** unaffected by: xBraf(V99E/T588A) [substitution]
    *** source: 16093354-Fig-9
  *** xErk1[tAb]IP phos(TEY)[phosAb] is increased itpo xMek1(S218D/S222D)"CA"
    *** cells: COS7 in BMLS
    *** enhanced by: Egf (10 min) [stim]
    *** source: 12738796-Fig-2e
  *** xErk1[tAb]IP phos(TEY)[phosAb] is increased itpo xMlk3
    *** cells: COS7 in BMLS
    *** inhibited by: SP600125 [addition]
    *** source: 12738796-Fig-4a
  *** xErk1[tAb]IP phos(TEY)[phosAb] is increased itpo xMlk3
    *** cells: COS7 in BMLS
    *** unaffected by: Egf (10 min) [stim]
    *** inhibited by: xMlk3(K144A)"KD" [substitution]
    *** source: 12738796-Fig-2e
  *** xErk1[tAb]IP phos(TEY)[phosAb] is increased itpo xMlk3
    *** cells: COS7 in BMLS
    *** unaffected by: xMkk4(S220A/T224L)"DN" [addition]
    *** source: 12738796-Fig-3b
  *** xErk1[tAb]IP phos(TEY)[phosAb] is increased itpo xRaf1
    *** cells: COS7 in BMLS
    *** inhibited by: xRaf1(S471A) [substitution]
    *** inhibited by: xRaf1(S471C) [substitution]
    *** inhibited by: xRaf1(S471D) [substitution]
    *** inhibited by: xRaf1(S471T) [substitution]
    *** source: 16093354-Fig-7b
  *** xErk1[tAb]IP phos(TEY)[phosAb] is increased itpo xRaf1
    *** cells: COS7 in BMLS
    *** partially inhibited by: xRaf1(S481A) [substitution]
    *** partially inhibited by: xRaf1(S481C) [substitution]
    *** partially inhibited by: xRaf1(S481D) [substitution]
    *** partially inhibited by: xRaf1(S481T) [substitution]
    *** source: 16093354-Fig-7c
  *** xErk1[tAb]IP phos(TEY)[phosAb] is increased itpo xRaf1(del(66-303))"CA"
    *** cells: COS7 in BMLS
    *** inhibited by: xRaf1(del(66-303)/S471A) [substitution]
    *** source: 16093354-Fig-8a
  *** xErk1[tAb]IP phos(TEY)[phosAb] is increased itpo xRaf1(del(66-303))"CA"
    *** cells: COS7 in BMLS
    *** source: 12738796-Fig-3b
  *** xErk1[tAb]IP phos(TEY)[phosAb] is increased itpo xRaf1(S338D/Y341D/T491E/S494D)"CA"
    *** cells: NIH3T3 in BMLS
    *** unaffected by: xPak1(83-149)"DN" [addition]
    *** source: 16129686-Fig-7
  *** xErk1[tAb]IP phos(TEY)[phosAb] is unchanged itpo xMlk3
    *** cells: COS7 in BMLS
    *** source: 12738796-Fig-4b
  *** rErk2 IVKA(MBP)[32P-ATP] is unchanged by rMkk3
    *** cells: none
    *** source: 8226933-Fig-1b
*** Erk2--
  *** rErk2(del(241-272))[XFP] nuc-import[IHC] is detectable
    *** cells: REF52 in BMS
    *** partially inhibited by: rPea15 [addition]
    *** source: 14707138-Fig-4c
  *** rErk2(K52M)"KD"[phosAb] phos(TEY)[phosAb] is increased by (rPak2 + rMek1)
    *** cells: none
    *** inhibited by: rMek1(K97A)"KD" [substitution]
    *** inhibited by: rMek1(S298A) [substitution]
    *** inhibited by: rMek1(S281A/S222A) [substitution]
    *** source: 17314031-Fig-5b
  *** rErk2(K52M)"KD"[phosAb] phos(TEY)[phosAb] is increased by (rPak2 + rMek1)
    *** cells: none
    *** inhibited by: rMek1(K97A)"KD" [substitution]
    *** inhibited by: rMek1(S298A) [substitution]
    *** unaffected by: rMek1(T292A) [substitution]
    *** reqs: rPak2 [omission]
    *** reqs: rMek1 [omission]
    *** source: 17314031-Fig-4b
  *** rErk2(K52M)"KD"[phosAb] phos(TEY)[phosAb] is increased by (rPak2 + rMek1)
    *** cells: none
    *** inhibited by: U0126 [addition]
    *** source: 17314031-Fig-5a
  *** rErk2(K52M)"KD"[phosAb] phos(TEY)[phosAb] is increased by (rPak3 + rMek1)
    *** cells: none
    *** inhibited by: rMek1(K97A)"KD" [substitution]
    *** inhibited by: rMek1(S298A) [substitution]
    *** unaffected by: xMek1(T292A) [substitution]
    *** reqs: rPak3 [omission]
    *** source: 17314031-Fig-4a
  *** rErk2[32P] phos[32P-ATP] is unchanged by rMkk3
    *** cells: none
    *** source: 7839144-Fig-2a
  *** rErk2[32P] phos[32P-ATP] is unchanged by rMkk4
    *** cells: none
    *** source: 7839144-Fig-3a
  *** rErk2[32P] phos[32P-ATP] is unchanged by rMkk6
    *** cells: none
    *** source: 8622669-Fig-6a
  *** rErk2[Ab] boundby[WB] rIqGap1[GST] is detectable
    *** cells: none
    *** source: 14970219-Fig-1a
  *** rErk2[Ab] boundby[WB] rIqGap1[GST] is detectable
    *** cells: none
    *** unaffected by: rMek1 [addition]
    *** source: 16135787-Fig-10a
  *** rErk2[Ab] boundby[WB] rIqGap1[GST] is detectable
    *** cells: none
    *** unaffected by: rMek2 [addition]
    *** source: 16135787-Fig-10a
  *** rErk2[Ab] boundby[WB] rPea15[GST] is detectable
    *** cells: none
    *** source: 11702783-Fig-5c
  *** Erk2[Ab] copptby[WB] Cdk2[Ab] is detectable
    *** cells: KIT225 in BMS "IL2-deprived" "treated with IL2 for 28 hr"
    *** source: 10962581-Fig-1c
  *** Erk2[Ab] copptby[WB] CyclinEs[Ab] is detectable
    *** cells: KIT225 in BMS "IL2-deprived" "treated with IL2 for 28 hr"
    *** source: 10962581-Fig-1d
  *** Erk2[Ab] copptby[WB] Mekk1[Ab] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: Nocodazole [addition]
    *** unaffected by: Sorbitol (30 min) [stim]
    *** source: 10969079-Fig-8a
  *** xErk2[Ab] copptby[WB] Mekk1[Ab] is detectable
    *** cells: HEK293T in BMLS
    *** enhanced by: Sorbitol (1 hr) [stim]
    *** unaffected by: Serum (30 min) [stim]
    *** source: 12049732-Fig-2b
  *** xErk2[Ab] copptby[WB] xArrb1[tAb] is detectable
    *** cells: COS7<xAgtR1><xErk2><xArrb1> in BMLS
    *** unaffected by: xRaf1 [addition]
    *** comment: xRaf1 increases the phos(TEY) of ppt Erk2
    *** source: 11777902-Fig-5a
  *** xErk2[Ab] copptby[WB] xArrb2[tAb] is detectable
    *** cells: COS7<xAgtR1><xErk2><xArrb2> in BMLS
    *** unaffected by: xRaf1 [addition]
    *** comment: xRaf1 increases the phos(TEY) of ppt Erk2
    *** source: 11777902-Fig-5a
  *** Erk2[Ab] copptby[WB] xMsk1[tAb] is detectable
    *** cells: HEK293 in BMLS
    *** unaffected by: UV (30 min) [stim]
    *** unaffected by: PMA (10 min) [stim]
    *** inhibited by: xMsk1(L740A)"Mapk-docking-mut" [substitution]
    *** inhibited by: xMsk1(R743A/R744A)"Mapk-docking-mut" [substitution]
    *** unaffected by: xMsk1(S750A/S752A) [substitution]
    *** unaffected by: xMsk1(S758A) [substitution]
    *** source: 15568999-Fig-8
  *** xErk2[Ab] copptby[WB] xPea15[tAb] is detectable
    *** cells: CHO<xPea15><xErk2> in BMS
    *** source: 11702783-Fig-5d
  *** Erk2[Ab] locatedin(nucleus)[IHC] is increased itpo xDusp5
    *** cells: COS1 in BMS
    *** source: 15713638-Fig-9d
  *** Erk2[Ab]IP IVKA(EgfR)[32P-ATP] is increased itpo xMekk1(del(Nterm))"CA"
    *** cells: COS in BMS
    *** source: 9305638-Fig-4b
  *** Erk2[Ab]IP IVKA(EgfR)[32P-ATP] is increased itpo xMekk2(del(Nterm))"CA"
    *** cells: COS in BMS
    *** source: 9305638(D)
  *** Erk2[Ab]IP IVKA(EgfR)[32P-ATP] is increased itpo xMekk3(del(Nterm))"CA"
    *** cells: COS in BMS
    *** source: 9305638(D)
  *** Erk2[Ab]IP IVKA(EgfR)[32P-ATP] is increased itpo xMekk4(del(Nterm))"CA"
    *** cells: COS in BMS
    *** source: 9305638(D)
  *** Erk2[Ab]IP IVKA(EgfR)[32P-ATP] is unchanged itpo xMekk4(CatDom)"CA"
    *** cells: HEK293 in BMS
    *** source: 9079650-Fig-5
  *** Erk2[Ab]IP IVKA(Elk1)[32P-ATP] is unchanged itpo xRipk1
    *** cells: HEK293 in BMS
    *** source: 16291755-Fig-3a
  *** Erk2[Ab]IP IVKA(Elk1)[32P-ATP] is unchanged itpo xTraf2
    *** cells: HEK293 in BMS
    *** source: 16291755-Fig-3c
  *** xErk2[Ab]IP IVKA(MBP)[32P-ATP] is detectable
    *** cells: 32D<xCsf1R> in BMLS
    *** inhibited by: xHras(S17N)"DN" [addition]
    *** source: 10958675-Fig-3b
  *** xErk2[Ab]IP IVKA(MBP)[32P-ATP] is detectable
    *** cells: 32D<xCsf1R> in BMLS
    *** partially inhibited by: xSrc(1-251)"DN" [addition]
    *** source: 10958675-Fig-9c
  *** xErk2[Ab]IP IVKA(MBP)[32P-ATP] is increased itpo (xCrkL + xRapGef1)
    *** cells: PC12 in BMLS
    *** source: 9560161-Fig-2c
  *** xErk2[Ab]IP IVKA(MBP)[32P-ATP] is increased itpo xCdc42(Q61L)"CA"
    *** cells: COS7 in BMS
    *** source: 11285260-Fig-4a
  *** xErk2[Ab]IP IVKA(MBP)[32P-ATP] is increased itpo xHras(G12V)"CA"
    *** cells: COS7 in BMS
    *** source: 11285260-Fig-1b
  *** xErk2[Ab]IP IVKA(MBP)[32P-ATP] is increased itpo xHras(G12V)"CA"
    *** cells: COS7 in BMS
    *** source: 11285260-Fig-1d
  *** xErk2[Ab]IP IVKA(MBP)[32P-ATP] is increased itpo xHras(G12V)"CA"
    *** cells: COS7 in BMS
    *** unaffected by: xArhGap1 [addition]
    *** source: 11285260-Fig-1d
  *** xErk2[Ab]IP IVKA(MBP)[32P-ATP] is increased itpo xHras(G12V)"CA"
    *** cells: COS7 in BMS
    *** unaffected by: xArhGdia [addition]
    *** source: 11285260-Fig-1b
  *** xErk2[Ab]IP IVKA(MBP)[32P-ATP] is increased itpo xHras(G12V)"CA"
    *** cells: COS7 in BMS
    *** unaffected by: xArhGdia [addition]
    *** source: 11285260-Fig-1d
  *** xErk2[Ab]IP IVKA(MBP)[32P-ATP] is increased itpo xHras(G12V)"CA"
    *** cells: COS7 in BMS
    *** unaffected by: xCdc42(T17N) [addition]
    *** source: 11285260-Fig-1b
  *** xErk2[Ab]IP IVKA(MBP)[32P-ATP] is increased itpo xHras(Q61L)"CA"
    *** cells: 32D<xCsf1R> in BMLS
    *** source: 10958675-Fig-4c,4d
  *** xErk2[Ab]IP IVKA(MBP)[32P-ATP] is increased itpo xRaf1(del(66-303))"CA"
    *** cells: COS7 in BMS
    *** source: 8805275-Fig-5a
  *** xErk2[Ab]IP IVKA(MBP)[32P-ATP] is increased itpo xRasGrf1
    *** cells: NIH3T3<xHras> in BMLS
    *** source: 9430727-Fig-2
  *** Erk2[Ab]IP IVKA(MBP)[32P-ATP] is increased itpo xRras2(G23V)"CA"
    *** cells: NIH3T3 in BMLS
    *** source: 10064593-Fig-1a
  *** xErk2[Ab]IP IVKA(MBP)[32P-ATP] is unchanged itpo xMekk1
    *** cells: NIH3T3<xErk1> in BMLS
    *** source: 8548291-Fig-6e
  *** xErk2[Ab]IP IVKA(MBP)[32P-ATP] is unchanged itpo xPak1(L107F)"CA"
    *** cells: COS7 in BMS
    *** source: 8805275-Fig-5a
  *** xErk2[Ab]IP IVKA(MBP)[32P-ATP] is unchanged itpo xRasGrf1
    *** cells: NIH3T3<xKras> in BMLS
    *** comment: xKras-splice-variant-2 (aka 4B, 2B, PO1118-2) is used
    *** source: 9430727-Fig-2
  *** xErk2[Ab]IP IVKA(MBP)[32P-ATP] is unchanged itpo xRasGrf1
    *** cells: NIH3T3<xNras> in BMLS
    *** source: 9430727-Fig-2
  *** Erk2[Ab]IP phos(TEY)[phosAb] is increased itpo xFak2
    *** cells: HEK293T in BMLS
    *** inhibited by: xFak2(Y402F) [substitution]
    *** unaffected by: xFak2(Y881F) [substitution]
    *** source: 10329689-Fig-3b
  *** xErk2[Ab]IP ubiq[UbAb] is detectable
    *** cells: HEK293T in BMLS
    *** source: 12049732-Fig-5c
  *** Erk2[MS] copptby[WB] xKsr1[tAb] is detectable
    *** cells: COS in BMS
    *** source: 12932319-Fig-1a
  *** xErk2[phosAb] phos(TEY)[phosAb] is decreased itpo xDusp5
    *** cells: COS1<xErk2> in BMS "stimulated with serum"
    *** unaffected by: xDusp5(R12G/K13A/R16G/K17A) [substitution]
    *** source: 15713638-Fig-8c
  *** xErk2[phosAb] phos(TEY)[phosAb] is decreased itpo xDusp6
    *** cells: COS1<xErk2> in BMLS "stimulated with serum for 30 min"
    *** source: 15269220-Fig-7c
  *** xErk2[phosAb] phos(TEY)[phosAb] is decreased itpo xDusp6(L117A/L118A/L119A)
    *** cells: COS1<xErk2> in BMLS "stimulated with serum for 30 min"
    *** source: 15269220-Fig-7c
  *** xErk2[phosAb] phos(TEY)[phosAb] is increased itpo xFak2
    *** cells: HEK293T in BMLS
    *** inhibited by: xFak2(Y402F) [substitution]
    *** unaffected by: xFak2(Y881F) [substitution]
    *** source: 10329689-Fig-3a
  *** xErk2[phosAb] phos(TEY)[phosAb] is increased itpo xFgfR1
    *** cells: HEK293T<xErk2> in BMS
    *** inhibited by: xSpry2 [addition]
    *** inhibited by: xSpry2(T52A) [addition]
    *** partially inhibited by: xSpry2(N53A) [addition]
    *** inhibited by: xSpry2(E54A) [addition]
    *** unaffected by: xSpry2(Y55A) [addition]
    *** inhibited by: xSpry2(T56A) [addition]
    *** inhibited by: xSpry2(E57A) [addition]
    *** inhibited by: xSpry2(G58A) [addition]
    *** partially inhibited by: xSpry2(P59A) [addition]
    *** source: 12815057-Fig-6b
  *** xErk2[phosAb] phos(TEY)[phosAb] is increased itpo xRaf1
    *** cells: COS7<xAgtR1><xErk2> in BMLS
    *** unaffected by: xArrb1 [addition]
    *** unaffected by: xArrb2 [addition]
    *** source: 11777902-Fig-5a
  *** rErk2[tAb] boundby[WB] rNup153(mnr)"C"[GST] is detectable
    *** cells: none
    *** inhibited by: rPea15 [addition]
    *** source: 14707138-Fig-7
  *** xErk2[tAb] copptby[WB] Raf1[Ab] is undetectable
    *** cells: COS7 in BMS
    *** source: 10801873-Fig-4b
  *** xErk2[tAb] copptby[WB] xGadd45b[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 14743220-Fig-1a
  *** xErk2[tAb] copptby[WB] xGit1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xGit1(590-770) [substitution]
    *** source: 15923189-Fig-4b
  *** xErk2[tAb] copptby[WB] xLamtor3[tAb] is undetectable
    *** cells: CCL39 in BMS
    *** source: 9733512-Fig-3a
  *** xErk2[tAb] copptby[WB] xMekk1[tAb] is detectable
    *** cells: HEK293T in BMLS
    *** source: 12049732-Fig-5a
  *** xErk2[tAb] copptby[WB] xMkk4[tAb] is undetectable
    *** cells: COS1 in BMS
    *** source: 9808624-Fig-6a
  *** xErk2[tAb] IVKA(MBP)[32P-ATP] is increased itpo xMkk6
    *** cells: HEK293T<xErk2> in BMS
    *** source: 9890973-Fig-4c
  *** xErk2[tAb] IVKA(MBP)[32P-ATP] is unchanged itpo xMap4k4
    *** cells: HEK293T<xErk2> in BMS
    *** source: 9890973-Fig-4c
  *** xErk2[tAb] locatedin(nucleus-cytoplasm)[IHC] is detectable
    *** cells: CCL39<xErk2> in BMLS
    *** source: 8392845-Fig-5a
  *** xErk2[tAb] snaggedby[WB] rIqGap1[GST] is detectable
    *** cells: MCF7 in BMS
    *** source: 14970219-Fig-1b
  *** xErk2[tAb] snaggedby[WB] rIqGap1[GST] is detectable
    *** cells: MCF7 in BMS
    *** unaffected by: Egf (10 min) [stim]
    *** source: 14970219-Fig-2
  *** xErk2[tAb]IP IVKA(Elk1)[32P-ATP] is increased itpo xMekk1
    *** cells: HELA<xErk2> in BMLS
    *** source: 8846788-Fig-3b
  *** xErk2[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xHras(Q61L)"CA"
    *** cells: COS1 in BMS
    *** source: 9427749-Fig-3b
  *** xErk2[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMlk2
    *** cells: COS1 in BMS
    *** source: 9427749-Fig-3b
  *** xErk2[tAb]IP IVKA(Jun)[32P-ATP] is unchanged itpo xAsk1
    *** cells: COS1 in BMS
    *** source: 8940179-Fig-5
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is decreased itpo xDusp5
    *** cells: COS1<xErk2> in BMS "stimulated with serum"
    *** inhibited by: xDusp5(R53A/R54A) [substitution]
    *** source: 15713638-Fig-4b
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is decreased itpo xDusp5
    *** cells: COS1<xErk2> in BMS "stimulated with serum"
    *** source: 15713638-Fig-2a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is detectable
    *** cells: HEK293T in BMLS
    *** source: 12049732-Fig-5b
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is detectable
    *** cells: PC12 in BMLS
    *** inhibited by: xHras(S17N)"DN" [addition]
    *** source: 9094716-Fig-2d
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo (xBraf + xCrkL)
    *** cells: PC12<xRap1a> in BMLS
    *** reqs: both [omissions]
    *** inhibited by: xRap1a(T17N)"DN" [substitution]
    *** source: 9560161-Fig-5a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo (xCdc42 + xRaf1)
    *** cells: HEK293 in BMLS
    *** reqs: both [omissions]
    *** source: 9351825-Fig-1a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo (xCdc42(G12V)"CA" + xRaf1)
    *** cells: HEK293 in BMLS
    *** reqs: both [omissions]
    *** source: 9351825-Fig-1a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo (xCdc42(G12V)"CA" + xRaf1)
    *** cells: HEK293 in BMLS
    *** unaffected by: xRac2(T17N)"DN" [addition]
    *** unaffected by: xRhoa(T17N)"DN" [addition]
    *** source: 9351825-Fig-6a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo (xGnb1 + xGng1)
    *** cells: COS7 in BMLS
    *** source: 11323411(D)
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo (xPak1(165-544)"CA" + xRaf1)
    *** cells: HEK293 in BMLS
    *** reqs: both [omissions]
    *** inhibited by: xRac2(T17N)"DN" [addition]
    *** inhibited by: xCdc42(T17N)"DN" [addition]
    *** source: 9351825-Fig-6a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo (xRac1 + xRaf1)
    *** cells: HEK293 in BMLS
    *** reqs: both [omissions]
    *** source: 9351825-Fig-1a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo (xRac2(G12V)"CA" + xRaf1)
    *** cells: HEK293 in BMLS
    *** reqs: both [omissions]
    *** unaffected by: xCdc42(T17N)"DN" [addition]
    *** unaffected by: xRhoa(T19N)"DN" [addition]
    *** source: 9351825-Fig-1a,6a,6b
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo (xRhoa(Q63L)"CA" + xRaf1)
    *** cells: HEK293 in BMLS
    *** reqs: both [omissions]
    *** inhibited by: xRac2(T17N)"DN" [addition]
    *** inhibited by: xCdc42(T17N)"DN" [addition]
    *** source: 9351825-Fig-1a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xBraf(437-766)
    *** cells: HEK293<xErk2> in BMLS
    *** enhanced by: xBraf(437-766/T599E/S602D) [substitution]
    *** inhibited by: xBraf(437-766/T599A/S602A) [substitution]
    *** source: 15710605-Fig-8a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xBraf(437-766)"CatDomain"
    *** cells: HEK293<xErk2> in BMLS
    *** inhibited by: xBraf(1-436) [addition]
    *** inhibited by: xBraf(1-375) [addition]
    *** inhibited by: xBraf(1-346) [addition]
    *** partially inhibited by: xBraf(1-281) [addition]
    *** inhibited by: xBraf(101-436) [addition]
    *** inhibited by: xBraf(101-346) [addition]
    *** source: 15710605-Fig-3b
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xBraf(437-766)"CatDomain"
    *** cells: HEK293<xErk2> in BMLS
    *** inhibited by: xBraf(1-436) [addition]
    *** inhibited by: xBraf(1-436/S446A) [addition]
    *** source: 15710605-Fig-7a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xBraf(437-766)"CatDomain"
    *** cells: HEK293<xErk2> in BMLS
    *** inhibited by: xBraf(1-436) [addition]
    *** source: 15710605-Fig-8a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xBraf(437-766)"CatDomain"
    *** cells: HEK293<xErk2> in BMLS
    *** inhibited by: xBraf(1-436) [addition]
    *** source: 15710605-Fig-9a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xBraf(437-766)"CatDomain"
    *** cells: HEK293<xErk2> in BMLS
    *** inhibited by: xBraf(1-436)"RegDomain" [addition]
    *** inhibited by: xRaf1(1-330)"RegDomain" [addition]
    *** source: 15710605-Fig-5a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xBraf(437-766)"CatDomain"
    *** cells: HEK293<xErk2> in BMLS
    *** inhibited by: xBraf(1-436)"RegDomain" [addition]
    *** source: 15710605-Fig-2c
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xBraf(437-766)"CatDomain"
    *** cells: HEK293<xErk2> in BMLS
    *** source: 15710605-Fig-2a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xBraf(437-766/T599E/S602D)
    *** cells: HEK293<xErk2> in BMLS
    *** unaffected by: xBraf(1-436) [addition]
    *** source: 15710605-Fig-8a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xBraf(V600E)
    *** cells: HEK293<xErk2> in BMLS
    *** unaffected by: xBraf(1-436) [addition]
    *** source: 15710605-Fig-7a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xCdc42(Q61L)"CA"
    *** cells: COS1 in BMS
    *** source: 7499279-Fig-5
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xFak2
    *** cells: HEK293T in BMLS
    *** inhibited by: xFak2(Y402F) [substitution]
    *** unaffected by: xFak2(Y881F) [substitution]
    *** source: 10329689-Fig-3a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xFak2
    *** cells: HEK293T in BMS
    *** enhanced by: xGrb2 [addition]
    *** partially inhibited by: xGrb2(del(Nterm-SH3)) [addition]
    *** partially inhibited by: xGrb2(del(Cterm-SH3)) [addition]
    *** partially inhibited by: xSos1(Cterm) [addition]
    *** unaffected by: xCrk [addition]
    *** source: 10329689-Fig-4a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xFak2
    *** cells: HEK293T in BMS
    *** unaffected by: xBcar1(del(213-514))"substrate-domain-mut" [addition]
    *** unaffected by: xCrk(R38V)"SH2-domain-mut" [addition]
    *** source: 10329689-Fig-6a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xHras(G12R)"CA"
    *** cells: NIH3T3 in BMLS
    *** source: 10803462-Fig-1
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xHras(G12V)"CA"
    *** cells: COS7 in BMLS
    *** source: 10473620-Fig-3b
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xHras(G12V)"CA"
    *** cells: COS7 in BMS
    *** inhibited by: xHras(G12V/D38A) [substitution]
    *** inhibited by: xHras(G12V/D38E) [substitution]
    *** inhibited by: xHras(G12V/Y40C) [substitution]
    *** source: 8999998-Fig-2b
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xHras(G12V)"CA"
    *** cells: HEK293 in BMLS
    *** source: 9351825-Fig-1a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xHras(G12V)"CA"
    *** cells: HEK293 in BMS
    *** source: 8668187-Fig-1a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xHras(G12V)"CA"
    *** cells: HEK293T in BMS
    *** source: 10835426-Fig-5
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xHras(G12V)"CA"
    *** cells: PC12 in BMLS
    *** source: 10473620-Fig-3a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xHras(mnr)"CA"
    *** cells: HEK293 in BMS
    *** source: 9135144-Fig-5c
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xHras(Q61L)"CA"
    *** cells: NIH3T3 in BMLS
    *** source: 10446149-Fig-5a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xMadd
    *** cells: COS in BMS
    *** source: 9115275-Fig-6
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xMekk1
    *** cells: COS1 in BMS
    *** source: 9808624-Fig-1e
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xMekk1
    *** cells: HEK293T in BMLS
    *** source: 12049732-Fig-5b
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xMekk1
    *** cells: NIH3T3 in BMLS
    *** source: 9006902-Fig-2b
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xMekk1
    *** cells: NotReported in BMS
    *** source: 8643568-Fig-7
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xMekk3
    *** cells: NIH3T3 in BMLS
    *** source: 9006902-Fig-2b
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xMlk3
    *** cells: COS7 in BMLS
    *** inhibited by: xRasGrf1 [addition]
    *** source: 11285260-Fig-4c
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xMras(Q71L)"CA"
    *** cells: NIH3T3 in BMLS
    *** source: 10803462-Fig-1
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xRaf1(del(66-303))"CA"
    *** cells: HEK293 in BMS
    *** source: 8668187-Fig-4a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xRaf1(del(66-303))"CA"
    *** cells: NIH3T3 in BMLS
    *** source: 9006902-Fig-2b
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xRaf1(mnr)"CAAX"
    *** cells: COS7 in BMS
    *** source: 8999998-Fig-2b
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xRap1a(G12V)"CA"
    *** cells: PC12 in BMLS
    *** unaffected by: xHras(S17N)"DN" [addition]
    *** inhibited by: xMek1(K97R)"DN" [addition]
    *** source: 9094716-Fig-4a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xRap1a(S179D)"CA"
    *** cells: PC12 in BMLS
    *** source: 9094716-Fig-4a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xRasGrf1
    *** cells: COS7 in BMLS
    *** source: 11285260-Fig-4b
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xRasGrf1
    *** cells: COS7 in BMS
    *** inhibited by: xArhGdia [addition]
    *** inhibited by: xArhGap1 [addition]
    *** source: 11285260-Fig-1d
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xRasGrf1
    *** cells: COS7 in BMS
    *** inhibited by: xCdc42(T17N) [addition]
    *** inhibited by: xArhGdia [addition]
    *** source: 11285260-Fig-1b
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xRasGrf1
    *** cells: COS7 in BMS
    *** source: 14749369-Fig-6a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xRasGrf1
    *** cells: HEK293 in BMS
    *** unaffected by: xTnk2 [addition]
    *** enhanced by: xCdc42(G12V)"CA" + xTnk2 [addition]
    *** source: 10882715-Fig-7a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xRasGrf2
    *** cells: COS7 in BMS
    *** source: 14749369-Fig-6a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xRasGrp1
    *** cells: HEK293T in BMS
    *** source: 10835426-Fig-5
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xRasGrp3
    *** cells: HEK293T in BMS
    *** source: 10835426-Fig-5
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xSos1
    *** cells: COS7 in BMS
    *** source: 14749369-Fig-6a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xTnk2(L543F)"CA"
    *** cells: HEK293 in BMS
    *** inhibited by: xTnk2(K214R) [substitution]
    *** enhanced by: xRasGrf1 [addition]
    *** source: 10882715-Fig-7b
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xAsk1
    *** cells: COS7 in BMS
    *** source: 8974401-Fig-2a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xAxin1
    *** cells: HEK293T<xErk2> in BMS
    *** unaffected by: xAxin1(1-600)"C1" [substitution]
    *** source: 10575011-Fig-1a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xCdc42(G12V)"CA"
    *** cells: COS7 in BMLS
    *** source: 10473620-Fig-3b
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xCdc42(G12V)"CA"
    *** cells: HEK293 in BMLS
    *** source: 9351825-Fig-1a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xCdc42(G12V)"CA"
    *** cells: HEK293 in BMS
    *** source: 8668187-Fig-4b
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xCdc42(G12V)"CA"
    *** cells: PC12 in BMLS
    *** source: 10473620-Fig-3a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xLamtor3
    *** cells: NIH3T3 in BMLS
    *** source: 9733512-Fig-4
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xMap4k4
    *** cells: HEK293 in BMS
    *** source: 9135144-Fig-5c
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xMek5(mnr)"CA"
    *** cells: NIH3T3 in BMS
    *** source: 10669751-Fig-5a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xMekk1
    *** cells: NIH3T3 in BMS
    *** source: 10669751-Fig-5a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xMekk4
    *** cells: COS7 in BMS
    *** source: 9305639-Fig-7c
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xMekk4
    *** cells: HELA in BMS
    *** source: 9305639-Fig-7c
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xMkk3(S189E/T193E)
    *** cells: COS1 in BMS
    *** source: 8622669-Fig-2a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xMkk6
    *** cells: NIH3T3 in BMS
    *** source: 10669751-Fig-5a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xMlk3
    *** cells: COS7 in BMS
    *** source: 8910292-Fig-2
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xMras(Q71L)"CA"
    *** cells: NIH3T3 in BMLS
    *** source: 10446149-Fig-5a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xPak1
    *** cells: COS7 in BMLS
    *** source: 11285260-Fig-4c
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xPak1
    *** cells: HEK293 in BMS
    *** source: 8668187-Fig-1a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xPak1(165-544)"CA"
    *** cells: HEK293 in BMLS
    *** source: 9351825-Fig-6b
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xPak2
    *** cells: HEK293 in BMS
    *** source: 8668187-Fig-1a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xPik3c?(mnr)"CAAX"
    *** cells: COS7 in BMS
    *** source: 8999998-Fig-2b
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xPik3c?(mnr)"CAAX"
    *** cells: COS7<xErk2> in BMLS
    *** source: 10330169-Fig-3a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xRac1
    *** cells: HEK293 in BMS
    *** source: 8668187-Fig-1a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xRac1(G12V)"CA"
    *** cells: COS7 in BMLS
    *** source: 10473620-Fig-3b
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xRac1(G12V)"CA"
    *** cells: PC12 in BMLS
    *** source: 10473620-Fig-3a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xRac2(G12V)"CA"
    *** cells: HEK293 in BMLS
    *** source: 9351825-Fig-1a,6b
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xRac2(G12V)"CA"
    *** cells: HEK293 in BMS
    *** source: 8668187-Fig-1a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xRaf1
    *** cells: HEK293 in BMLS
    *** source: 9351825-Fig-1a,6a,6b
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xRasGrp2
    *** cells: HEK293T in BMS
    *** source: 10835426-Fig-5
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xRhoa(G12V)"CA"
    *** cells: COS7 in BMLS
    *** source: 10473620-Fig-3b
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xRhoa(G12V)"CA"
    *** cells: PC12 in BMLS
    *** source: 10473620-Fig-3a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xRhoa(Q63L)"CA"
    *** cells: HEK293 in BMLS
    *** source: 9351825-Fig-1a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xRras(G38V)"CA"
    *** cells: COS7 in BMS
    *** source: 8999998-Fig-2b
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xSh2d3a
    *** cells: HEK293 in BMS
    *** source: 10187783-Fig-7a
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xTnk2
    *** cells: COS7 in BMLS
    *** source: 11285260-Fig-4c
  *** xErk2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xWasp
    *** cells: COS7 in BMLS
    *** source: 11285260-Fig-4c
  *** xErk2[tAb]IP IVKA(Rps6)[32P-ATP] is unchanged itpo xPdpk1(51-556)
    *** cells: COS7<xErk2> in BMLS
    *** source: 10480933-Fig-7
  *** xErk2[tAb]IP phos(TEY)[phosAb] is decreased itpo xAbi1
    *** cells: COS in BMLS
    *** source: 11003655-Fig-4a
  *** xErk2[tAb]IP phos(TEY)[phosAb] is decreased itpo xAbi1
    *** cells: COS in BMLS
    *** source: 11003655-Fig-4c
  *** xErk2[tAb]IP phos(TEY)[phosAb] is decreased itpo xPtprh
    *** cells: HEK293 in BMLS
    *** reversed by: rPtprh(C1022S)"CIA" [substitution]
    *** source: 11278335-Fig-6a
  *** xErk2[tAb]IP phos(TEY)[phosAb] is decreased itpo xPtprh
    *** cells: HEK293 in BMLS
    *** reversed by: rPtprh(C1022S)"CIA" [substitution]
    *** source: 11278335-Fig-6b
  *** xErk2[tAb]IP phos(TEY)[phosAb] is decreased itpo xPtprh
    *** cells: HEK293 in BMLS
    *** reversed by: rPtprh(C1022S)"CIA" [substitution]
    *** source: 11278335-Fig-6c
  *** xErk2[tAb]IP phos(TEY)[phosAb] is detectable
    *** cells: HEK293T in BMLS
    *** source: 12049732-Fig-5a
  *** xErk2[tAb]IP phos(TEY)[phosAb] is increased itpo xAbl1(mnr)"vAbl"
    *** cells: COS in BMLS
    *** inhibited by: xAbl1(mnr)"KD" [substitution]
    *** inhibited by: xAbi1 [addition]
    *** source: 11003655(D)
  *** xErk2[tAb]IP phos(TEY)[phosAb] is increased itpo xBraf(437-766)"CatDomain"
    *** cells: HEK293<xErk2> in BMLS
    *** inhibited by: xBraf(1-436) [addition]
    *** inhibited by: xBraf(1-436/S446A) [addition]
    *** source: 15710605-Fig-7a
  *** xErk2[tAb]IP phos(TEY)[phosAb] is increased itpo xBraf(437-766)"CatDomain"
    *** cells: HEK293<xErk2> in BMLS
    *** source: 15710605-Fig-2a
  *** xErk2[tAb]IP phos(TEY)[phosAb] is increased itpo xHras(G12V)"CA"
    *** cells: COS1 in BMLS
    *** source: 12167697-Fig-4b
  *** xErk2[tAb]IP phos(TEY)[phosAb] is increased itpo xHras(G12V)"CA"
    *** cells: COS1 in BMLS
    *** unaffected by: xRac1(T17N)"DN" [addition]
    *** source: 12167697-Fig-4b
  *** xErk2[tAb]IP phos(TEY)[phosAb] is increased itpo xRaf1(mnr)"CAAX"
    *** cells: COS1 in BMLS
    *** source: 12167697-Fig-4b
  *** xErk2[tAb]IP phos(TEY)[phosAb] is increased itpo xSrc(mnr)"vSrc"
    *** cells: COS in BMLS
    *** unaffected by: xAbi1 [addition]
    *** source: 11003655(D)
  *** xErk2[tAb]IP phos[WBMS] is increased itpo xHras(Q61L)"CA"
    *** cells: HEK293T in BMLS
    *** source: 8631302-Fig-5
  *** xErk2[tAb]IP phos[WBMS] is unchanged itpo xRala(Q72L)"CA"
    *** cells: HEK293T in BMLS
    *** source: 8631302-Fig-5
  *** xErk2[tAb]IP Yphos[pYAb] is decreased itpo xPtprh
    *** cells: HEK293 in BMS
    *** reversed by: rPtprh(C1022S)"CIA" [substitution]
    *** reversed by: rPtprh(D988A)"CIA" [substitution]
    *** source: 11278335-Fig-3a
  *** xErk2[tAb]IP Yphos[pYAb] is unchanged itpo xMlk3
    *** cells: COS1 in BMS
    *** source: 9003778-Fig-3c
  *** xErk2[XFP] locatedin(cytoplasm)[IHC] is detectable
    *** cells: COS1<xDusp6(1-221)><xErk2> in BMS
    *** source: 15269220-Fig-10a
  *** xErk2[XFP] locatedin(cytoplasm)[IHC] is detectable
    *** cells: COS1<xDusp6(C293S)><xErk2> in BMS
    *** source: 15269220-Fig-10a
  *** xErk2[XFP] locatedin(cytoplasm)[IHC] is detectable
    *** cells: COS1<xDusp6(C293S/R64A/R65A)><xErk2> in BMS
    *** source: 15269220-Fig-10a
  *** xErk2[XFP] locatedin(cytoplasm)[IHC] is detectable
    *** cells: COS1<xDusp6><xErk2> in BMS
    *** source: 15269220-Fig-10a
  *** xErk2[XFP] locatedin(cytoplasm)[IHC] is increased itpo xDusp1
    *** cells: COS1<xErk2> in BMS
    *** source: 15713638-Fig-10b
  *** xErk2[XFP] locatedin(nucleus-cytoplasm)[IHC] is detectable
    *** cells: NIH3T3<xErk2> in BMS
    *** source: 15713638-Fig-9a
  *** xErk2[XFP] locatedin(nucleus)[IHC] is detectable
    *** cells: COS1<xDusp6(C293S/L167A/L170A)><xErk2> in BMS
    *** source: 15269220-Fig-10a
  *** xErk2[XFP] locatedin(nucleus)[IHC] is increased itpo xDusp5
    *** cells: COS1<xErk2> in BMS
    *** inhibited by: xDusp5(R12G/K13A/R16G/K17A) [substitution]
    *** source: 15713638-Fig-10a
  *** xErk2[XFP] locatedin(nucleus)[IHC] is increased itpo xDusp5
    *** cells: NIH3T3<xErk2> in BMS
    *** inhibited by: xDusp5(R12G/K13A/R16G/K17A) [substitution]
    *** inhibited by: xDusp5(R53A/R54A) [substitution]
    *** source: 15713638-Fig-9b
  *** rErk2[XFP] nuc-export[IHC] is detectable
    *** cells: BJ in BMS
    *** comment: enhanced by addition of cytosol and energy mix to export buffer
    *** source: 16595679-Fig-1a
  *** rErk2[XFP] nuc-export[IHC] is detectable
    *** cells: BJ in BMS
    *** comment: transport buffer contains cytosol and energy mix
    *** inhibited by: WGA [pretreatment]
    *** source: 16595679-Fig-2
  *** rErk2[XFP] nuc-export[IHC] is detectable
    *** cells: HELA in BMS
    *** comment: enhanced by addition of cytosol and energy mix to export buffer
    *** source: 16595679-Fig-1b
  *** rErk2[XFP] nuc-export[IHC] is detectable
    *** cells: HELA in BMS
    *** comment: transport buffer contains cytosol and energy mix
    *** does not req: Crm1 [RNAi]
    *** source: 16595679-Fig-4b
  *** rErk2[XFP] nuc-export[IHC] is detectable
    *** cells: HELA in BMS
    *** comment: transport buffer contains cytosol and energy mix
    *** inhibited by: WGA [pretreatment]
    *** source: 16595679-Fig-2
  *** rErk2[XFP] nuc-export[IHC] is detectable
    *** cells: HELA in BMS
    *** comment: transport buffer contains cytosol and energy mix
    *** unaffected by: LMB [pretreatment]
    *** source: 16595679-Fig-5a
  *** rErk2[XFP] nuc-export[IHC] is detectable
    *** cells: HELA in BMS
    *** comment: transport buffer does not contain cytosol and energy mix
    *** does not req: Crm1 [RNAi]
    *** source: 16595679-Fig-4f
  *** rErk2[XFP] nuc-export[IHC] is detectable
    *** cells: HELA in BMS
    *** comment: transport buffer does not contain cytosol and energy mix
    *** unaffected by: LMB [pretreatment]
    *** source: 16595679-Fig-5a
  *** rErk2[XFP] nuc-import[IHC] is detectable
    *** cells: BJ in BMS
    *** comment: partially reqs addition of energy mix to transport buffer
    *** comment: partially inhibited by addition of apyrase to transport buffer
    *** source: 16595679-Fig-3
  *** rErk2[XFP] nuc-import[IHC] is detectable
    *** cells: BJ in BMS
    *** comment: transport buffer contains cytosol and energy mix
    *** inhibited by: WGA [pretreatment]
    *** source: 16595679-Fig-2
  *** rErk2[XFP] nuc-import[IHC] is detectable
    *** cells: BJ in BMS
    *** comment: transport buffer contains cytosol and energy mix
    *** partially inhibited by: rErk2(Y261N) [substitution]
    *** source: 16595679-Fig-6c
  *** rErk2[XFP] nuc-import[IHC] is detectable
    *** cells: BJ in BMS
    *** comment: transport buffer does not contain cytosol and energy mix
    *** unaffected by: rErk2(Y261N) [substitution]
    *** source: 16595679-Fig-6c
  *** rErk2[XFP] nuc-import[IHC] is detectable
    *** cells: HELA in BMS
    *** comment: transport buffer contains cytosol and energy mix
    *** inhibited by: WGA [pretreatment]
    *** source: 16595679-Fig-2
  *** rErk2[XFP] nuc-import[IHC] is detectable
    *** cells: HELA in BMS
    *** inhibited by: rMek1 [addition]
    *** source: 16595679-Fig-6a
  *** rErk2[XFP] nuc-import[IHC] is detectable
    *** cells: REF52 in BMS
    *** comment: does not req energy or transport factors
    *** inhibited by: rPea15 [addition]
    *** source: 14707138-Fig-3a
  *** rErk2[XFP] nuc-import[IHC] is detectable
    *** cells: REF52 in BMS
    *** inhibited by: rPea15 [addition]
    *** source: 14707138-Fig-4c
  *** rErk2[XFP] nuc-import[IHC] is detectable
    *** cells: REF52 in BMS
    *** unaffected by: rErk2(D316A/D319A) [substitution]
    *** unaffected by: rErk2(del(241-272)) [substitution]
    *** comment: rErk2(WT) and rErk2(D316A/D319A) inhibited by addition of rPea15
    *** comment: rErk2(del(241-272)) unaffected by addition of rPea15
    *** source: 14707138-Fig-4a
  *** rErk2[XFP] nuc-import[IHC] is detectable
    *** cells: REF52 in BMS
    *** unaffected by: rErk2(K52R) [substitution]
    *** unaffected by: rErk2(T183A) [substitution]
    *** unaffected by: rErk2(H176E/L333A/L336A/L341A/L344A) [substitution]
    *** comment: all rErk2 mutants inhibited by addition of rPea15
    *** source: 14707138-Fig-6
  *** rErk2[XFP] nuc-import[IHC] is detectable
    *** cells: REF52 in BMS
    *** unaffected by: rErk2(Y261N) [substitution]
    *** comment: rErk2(WT) inhibited by addition of rPea15
    *** comment: rErk2(WT) unaffected by addition of rPea15(D74A)
    *** comment: rErk2(Y261N) unaffected by addition of rPea15
    *** source: 14707138-Fig-5
  *** rErk2{thiophos}[XFP] nuc-export[IHC] is undetectable
    *** cells: BJ in BMLS
    *** comment: transport buffer does not contain cytosol or energy mix
    *** source: 16595679-Fig-7c
  *** rErk2{thiophos}[XFP] nuc-import[IHC] is detectable
    *** cells: BJ in BMLS
    *** comment: enhanced by addition of energy mix
    *** source: 16595679-Fig-7c
  *** rErk2{thiophos}[XFP] nuc-import[IHC] is detectable
    *** cells: BJ in BMLS
    *** comment: enhanced by addition of rKpna1 + rKpnb1 + rNutf2 + rRan + energy mix
    *** unaffected by: WGA [pretreatment]
    *** source: 16595679-Fig-7a
  *** rErk2{thiophos}[XFP] nuc-import[IHC] is detectable
    *** cells: BJ in BMLS
    *** comment: transport buffer contains energy mix
    *** inhibited by: WGA [pretreatment]
    *** source: 16595679-Fig-7c
  *** rErk2{thiophos}[XFP] nuc-import[IHC] is detectable
    *** cells: BJ in BMLS
    *** comment: transport buffer does not contain cytosol or energy mix
    *** source: 16595679-Fig-7c
*** Erk5--
  *** xErk5[Ab] phos[WBMS] is increased itpo (xMekk2 + xMek5)
    *** cells: HEK293 in BMS
    *** inhibited by: xMek5(S311A/T315A)"DN" [addition]
    *** source: 11073940-Fig-3a
  *** xErk5[Ab] phos[WBMS] is increased itpo (xMekk3 + xMek5)
    *** cells: HEK293 in BMS
    *** reqs: xMek5 [omission]
    *** reqs: xMekk3 [omission]
    *** source: 11073940-Fig-2b
  *** xErk5[Ab] phos[WBMS] is increased itpo xMekk2
    *** cells: HEK293 in BMS
    *** enhanced by: xMek5 [addition]
    *** source: 11073940-Fig-2b,3a
  *** Erk5[Ab] phos[WBMS] is increased itpo xMekk3(12-626)"CA"
    *** cells: HEK293T in BMS
    *** inhibited by: xMek5(mnr)"DN" [addition]
    *** source: 10593883-Fig-3
  *** Erk5[Ab] phos[WBMS] is unchanged itpo (xArf4(Q71L)"CA" + xPld2)
    *** cells: HEK293T<xEgfR> in BMLS
    *** source: 12446727-Fig-7
  *** Erk5[Ab] phos[WBMS] is unchanged itpo xHras(G12V)"CA"
    *** cells: HELA in BMLS
    *** source: 9790194-Fig-2a
  *** Erk5[Ab] phos[WBMS] is unchanged itpo xMek1(mnr)"CA"
    *** cells: HEK293T<xEgfR> in BMLS
    *** source: 12446727-Fig-7
  *** Erk5[Ab] phos[WBMS] is unchanged itpo xRaf1(mnr)"BXB"
    *** cells: HELA in BMLS
    *** source: 9790194-Fig-2a
  *** Erk5[phosAb] phos(sitenr)[phosAb] is unchanged itpo xHras(Q61L)"CA"
    *** cells: PC6 in BMLS
    *** source: 15632082-Fig-1c
  *** Erk5[phosAb] phos(sitenr)[phosAb] is unchanged itpo xRin1(Q78L)
    *** cells: PC6 in BMLS
    *** source: 16157584-Fig-1d
  *** Erk5[phosAb] phos(sitenr)[phosAb] is unchanged itpo xRit1
    *** cells: PC6 in BMLS
    *** source: 15632082-Fig-1c
  *** Erk5[phosAb] phos(sitenr)[phosAb] is unchanged itpo xRit1(Q79L)"CA"
    *** cells: PC6 in BMLS
    *** source: 15632082-Fig-1c
  *** xErk5[tAb]IP IVKA(Elk1)[32P-ATP] is increased itpo xMek5(S311D/T315D)"CA"
    *** cells: COS7 in BMLS
    *** source: 10473620-Fig-6a
  *** xErk5[tAb]IP IVKA(Elk4)[32P-ATP] is increased itpo xMek5(S311D/T315D)"CA"
    *** cells: COS7 in BMLS
    *** source: 10473620-Fig-6a
  *** xErk5[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo (xMek5 + xMekk2)
    *** cells: HEK293 in BMS
    *** reqs: xMekk2 [omission]
    *** inhibited by: xMek5(S311A/T315A) [substitution]
    *** source: 11073940-Fig-2a
  *** xErk5[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo (xMek5 + xTpl2)
    *** cells: NIH3T3 in BMS
    *** reqs: xTpl2 [omission]
    *** source: 10669751-Fig-5c
  *** xErk5[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xCdc42(G12V)"CA"
    *** cells: PC12 in BMLS
    *** source: 10473620-Fig-3a
  *** xErk5[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xHras(G12V)"CA"
    *** cells: COS7 in BMLS
    *** source: 10473620-Fig-3b
  *** xErk5[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xHras(G12V)"CA"
    *** cells: PC12 in BMLS
    *** source: 10473620-Fig-3a
  *** xErk5[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xRac1(G12V)"CA"
    *** cells: PC12 in BMLS
    *** source: 10473620-Fig-3a
  *** xErk5[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xRhoa(G12V)"CA"
    *** cells: PC12 in BMLS
    *** source: 10473620-Fig-3a
  *** xErk5[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xTpl2
    *** cells: NIH3T3 in BMS
    *** source: 10669751-Fig-5c
  *** xErk5[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xCdc42(G12V)"CA"
    *** cells: COS7 in BMLS
    *** source: 10473620-Fig-3b
  *** xErk5[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xMek1(S218E/S222E)"CA"
    *** cells: NIH3T3 in BMS
    *** source: 10669751-Fig-5c
  *** xErk5[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xMekk1
    *** cells: NIH3T3 in BMS
    *** source: 10669751-Fig-5c
  *** xErk5[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xMkk6
    *** cells: NIH3T3 in BMS
    *** source: 10669751-Fig-5c
  *** xErk5[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xRac1(G12V)"CA"
    *** cells: COS7 in BMLS
    *** source: 10473620-Fig-3b
  *** xErk5[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xRhoa(G12V)"CA"
    *** cells: COS7 in BMLS
    *** source: 10473620-Fig-3b
*** Erks--
  *** Erks[Ab] copptby[WB] xKsr1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xKsr1(C857Y) [substitution]
    *** source: 10409742-Fig-2b,2c
  *** Erks[Ab] copptby[WB] xMnk2[tAb] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: xMnk2(T197A) [substitution]
    *** unaffected by: xMnk2(T202A) [substitution]
    *** unaffected by: xMnk2(T332A) [substitution]
    *** unaffected by: xMnk2(T332D) [substitution]
    *** unaffected by: xMnk2(T403A) [substitution]
    *** unaffected by: xMnk2(T403D) [substitution]
    *** source: 11154262-Fig-4b
  *** Erks[Ab] copptby[WB] xMnk2b[Ab] is undetectable
    *** cells: HEK293<xMnk2b> in BMS
    *** source: 12897141-Fig-2f
  *** Erks[Ab] copptby[WB] xRsk1[tAb] is detectable
    *** cells: HEK293<xRsk1> in BMLS
    *** enhanced by: xRsk1(K94R) [substitution]
    *** enhanced by: xRsk1(K447R) [substitution]
    *** enhanced by: xRsk1(K94R/K447R) [substitution]
    *** source: 12832467-Fig-5a
  *** Erks[Ab] copptby[WB] xRsk1[tAb] is detectable
    *** cells: HEK293<xRsk1> in BMLS
    *** inhibited by: xRsk1(1-721) [substitution]
    *** inhibited by: xRsk1(L722A) [substitution]
    *** inhibited by: xRsk1(R725A) [substitution]
    *** inhibited by: xRsk1(R726A) [substitution]
    *** inhibited by: xRsk1(K728A) [substitution]
    *** inhibited by: xRsk1(K729A) [substitution]
    *** unaffected by: xRsk1(L730A) [substitution]
    *** unaffected by: xRsk1(S732A) [substitution]
    *** source: 12832467-Fig-2b
  *** Erks[Ab] copptby[WB] xRsk1[tAb] is undetectable
    *** cells: COS7<xRsk3> in BMLS
    *** source: 8939914-Fig-5b
  *** Erks[Ab] copptby[WB] xRsk3[tAb] is detectable
    *** cells: COS7<xRsk3> in BMLS
    *** enhanced by: xRsk3(33-733) [substitution]
    *** inhibited by: xRsk3(1-689) [substitution]
    *** source: 8939914-Fig-5b
  *** Erks[Ab] infraction(DRM)[WB] is detectable
    *** cells: mEFs<Lamtor1~null><xLamtor1> in BMLS
    *** partially reqs: xLamtor1 [omission]
    *** source: 19177150-Fig-6e
  *** Erks[Ab] infraction(nuclear)[WB] is increased itpo xPea15(I15A)
    *** cells: CHO in BMLS
    *** inhibited by: xPea15(WT) [substitution]
    *** source: 11702783-Fig-4d
  *** Erks[Ab] locatedin(nucleus-cytoplasm)[IHC] is detectable
    *** cells: CCL39 in BMLS
    *** source: 9700154-Fig-1a
  *** Erks[Ab] locatedin(nucleus-cytoplasm)[IHC] is detectable
    *** cells: CCL39 in BMS
    *** comment: Erks are only in cyto itpo xDusp6(C293S)
    *** source: 9927426-Fig-2a
  *** Erks[Ab] locatedin(nucleus)[IHC] is decreased itpo xPea15
    *** cells: mAstrocytes<Pea15~null> in BMLS
    *** reversed by: rPea15(D74A) [substitution]
    *** source: 11702783-Fig-7e
  *** Erks[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: CCL39 in BMLS "treated with serum for 3 hr"
    *** inhibited by: xDusp6 [addition]
    *** inhibited by: xDusp6(C293S) [addition]
    *** source: 9927426-Fig-1b
  *** Erks[Ab] locatedin(nucleus)[IHC] is increased itao Pea15 [KO]
    *** cells: mAstrocytes in BMLS
    *** source: 11702783-Fig-3d
  *** Erks[Ab] locatedin(nucleus)[IHC] is increased itpo xRaf1(mnr)"CA"
    *** cells: CCL39 in BMLS
    *** inhibited by: PD98059 [cotreatment]
    *** source: 9700154-Fig-1
  *** Erks[Ab] snaggedby[WB] rPea15[GST] is detectable
    *** cells: CHO in BMS
    *** inhibited by: rPea15(79-130)"Cterm" [substitution]
    *** inhibited by: rPea15(1-80)"DED" [substitution]
    *** inhibited by: rPea15(D74A) [substitution]
    *** unaffected by: rPea15(S104A) [substitution]
    *** unaffected by: rPea15(S116A) [substitution]
    *** unaffected by: rPea15(S104A/S116A) [substitution]
    *** source: 11702783-Fig-7b
  *** Erks[Ab] snaggedby[WB] rPea15[GST] is detectable
    *** cells: CHO in BMS
    *** source: 11702783-Fig-5d
  *** Erks[Ab] snaggedby[WB] rPea15[GST] is detectable
    *** cells: CHO in BMS
    *** unaffected by: rPea15(I15A) [substitution]
    *** source: 11702783-Fig-7a
  *** Erks[Ab] snaggedby[WB] rPea15[GST] is detectable
    *** cells: CHO in BMS
    *** unaffected by: U0126 [pretreatment]
    *** source: 11702783-Fig-6a
  *** Erks[Ab] snaggedby[WB] rRsk2{phos}[GST] is detectable
    *** cells: HEK293T in BMS "treated with U0126"
    *** comment: rRsk2 was phosed by rSrc{act}
    *** inhibited by: rRsk2 [substitution]
    *** source: 18156174-Fig-8a
  *** Erks[Ab] snaggedby[WB] rRsk2{phos}[GST] is detectable
    *** cells: HEK293T in BMS "treated with U0126"
    *** comment: rRsk2 was phosed by rSrc{act}
    *** inhibited by: rRsk2 [substitution]
    *** source: 18156174-Fig-8b
  *** Erks[Ab] snaggedby[WB] rRsk2{phos}[GST] is detectable
    *** cells: HEK293T in BMS "treated with U0126"
    *** comment: rRsk2 was phosed by rSrc{act}
    *** inhibited by: rRsk2(Y529F){phos} [substitution]
    *** unaffected by: rRsk2(Y488F){phos} [substitution]
    *** source: 18156174-Fig-8b
  *** Erks[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xHras(Q61L)
    *** cells: CHO in BMLS
    *** source: 9111305-Fig-7b
  *** Erks[Ab]IP IVKA(Jun)[32P-ATP] is unchanged itpo xCdc42(Q61L)
    *** cells: CHO in BMLS
    *** source: 9111305-Fig-7b
  *** Erks[Ab]IP IVKA(Jun)[32P-ATP] is unchanged itpo xRac1(Q61L)
    *** cells: CHO in BMLS
    *** source: 9111305-Fig-7b
  *** Erks[Ab]IP IVKA(Jun)[32P-ATP] is unchanged itpo xRhoa(Q63L)
    *** cells: CHO in BMLS
    *** source: 9111305-Fig-7b
  *** Erks[Ab]IP IVKA(MBP)[32P-ATP] is detectable
    *** cells: C3H10T12 in BMLS "treated with PMA for 3 min"
    *** reqs: Pkce [AS-DNA]
    *** source: 11358964-Fig-3e
  *** Erks[Ab]IP IVKA(MBP)[32P-ATP] is detectable
    *** cells: THP1 in BMS
    *** inhibited by: xFak2(K457M)"KD" [addition]
    *** source: 9573036-Fig-5
  *** Erks[Ab]IP IVKA(MBP)[32P-ATP] is detectable-but unchanged itpo xMekk1
    *** cells: HELA in BMLS
    *** source: 8846788-Fig-2
  *** Erks[Ab]IP IVKA(MBP)[32P-ATP] is increased itpo xHras(G12D)
    *** cells: COS1 in BMS
    *** source: 8994827-Fig-5b
  *** Erks[Ab]IP IVKA(MBP)[32P-ATP] is increased itpo xHras(G12V)
    *** cells: NCIH82 in BMS
    *** source: 10667594-Fig-2a
  *** Erks[Ab]IP IVKA(MBP)[32P-ATP] is increased itpo xHras(mnr)"vRas"
    *** cells: EPH4 in BMS
    *** source: 10197981-Fig-4a
  *** Erks[Ab]IP IVKA(MBP)[32P-ATP] is increased itpo xSos1
    *** cells: COS1 in BMS
    *** source: 8994827-Fig-5b
  *** Erks[Ab]IP IVKA(MBP)[32P-ATP] is increased itpo xVav1
    *** cells: NIH3T3 in BMS
    *** source: 8289830-Fig-6
  *** Erks[Ab]IP IVKA(MBP)[32P-ATP] is unchanged itpo xDbl
    *** cells: COS1 in BMS
    *** source: 8994827-Fig-5b
  *** Erks[Ab]IP IVKA(MBP)[32P-ATP] is unchanged itpo xFgd1
    *** cells: COS1 in BMS
    *** source: 8994827-Fig-5b
  *** Erks[Ab]IP IVKA(MBP)[32P-ATP] is unchanged itpo xVav1
    *** cells: COS1 in BMS
    *** source: 8994827-Fig-5b
  *** Erks[phosAb] phos(TEY)[phosAb] is decreased irt U0126 (4 hr)
    *** cells: A375 in BMLS "Low-Glucose"
    *** source: 19274086-Fig-3a
  *** Erks[phosAb] phos(TEY)[phosAb] is decreased irt U0126 (4 hr)
    *** cells: SKMEL28 in BMLS "Low-Glucose"
    *** source: 19274086-Fig-3a
  *** Erks[phosAb] phos(TEY)[phosAb] is decreased itpo xAkt1(myr)"CA"
    *** cells: mEFs in BMS
    *** source: 16698790-Fig-6b
  *** Erks[phosAb] phos(TEY)[phosAb] is decreased itpo xDusp5
    *** cells: HEK293T<xIL2Rb><xJak3> in BMS
    *** reversed by: xDusp5(C263S)"CIA" [substitution]
    *** source: 12435740-Fig-5d
  *** Erks[phosAb] phos(TEY)[phosAb] is decreased itpo xMerlinb
    *** cells: HEI193 in BMS
    *** source: 20890305-Fig-3b
  *** Erks[phosAb] phos(TEY)[phosAb] is decreased itpo xMerlinb
    *** cells: RT4 in BMS
    *** source: 20890305-Fig-3a
  *** Erks[phosAb] phos(TEY)[phosAb] is decreased itpo xMerlinb
    *** cells: SKOV3 in BMS
    *** source: 20890305-Fig-3b
  *** Erks[phosAb] phos(TEY)[phosAb] is decreased itpo xMuc20
    *** cells: HEK293 in BMLS "treated with Hgf for 5 min"
    *** source: 15314156-Fig-2b
  *** Erks[phosAb] phos(TEY)[phosAb] is decreased itpo xPik3c2b
    *** cells: A431 in BMLS
    *** source: 16775008-Fig-4d
  *** Erks[phosAb] phos(TEY)[phosAb] is decreased itpo xRho?(S19N)"DN"
    *** cells: HELA in BMS
    *** source: 11847220-Fig-1b
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: A427 in BMLS
    *** does not req: Hras [RNAi]
    *** source: 16630891-Fig-7c
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: A427 in BMLS
    *** does not req: Nras [RNAi]
    *** source: 16630891-Fig-7c
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: A427 in BMLS
    *** partially reqs: Braf [RNAi]
    *** source: 16630891-Fig-7c
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: A427 in BMLS
    *** partially reqs: Shoc2 [RNAi]
    *** source: 16630891-Fig-7c
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: A427 in BMLS
    *** reqs: Kras [RNAi]
    *** source: 16630891-Fig-7c
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: A427 in BMLS "Kras-CA-mutation"
    *** partially reqs: Raf1 [RNAi]
    *** source: 16630891-Fig-7c
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: A549 in BMLS
    *** does not req: Braf [RNAi]
    *** source: 16630891-Fig-7d
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: A549 in BMLS
    *** does not req: Hras [RNAi]
    *** source: 16630891-Fig-7d
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: A549 in BMLS
    *** does not req: Nras [RNAi]
    *** source: 16630891-Fig-7d
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: A549 in BMLS
    *** partially reqs: Kras [RNAi]
    *** source: 16630891-Fig-7d
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: A549 in BMLS
    *** partially reqs: Shoc2 [RNAi]
    *** source: 16630891-Fig-7d
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: A549 in BMLS "Kras-CA-mutation"
    *** partially reqs: Raf1 [RNAi]
    *** source: 16630891-Fig-7d
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: ASPC1 in BMLS
    *** does not req: Nras [RNAi]
    *** source: 16630891-Fig-7b
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: ASPC1 in BMLS
    *** partially reqs: Braf [RNAi]
    *** partially reqs: Raf1 and/or Braf [DRNAi]
    *** source: 16630891-Fig-7b
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: ASPC1 in BMLS
    *** partially reqs: Hras [RNAi]
    *** source: 16630891-Fig-7b
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: ASPC1 in BMLS
    *** reqs: Kras [RNAi]
    *** source: 16630891-Fig-7b
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: ASPC1 in BMLS
    *** reqs: Shoc2 [RNAi]
    *** source: 16630891-Fig-7b
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: ASPC1 in BMLS "Kras-CA-mutation"
    *** partially reqs: Raf1 [RNAi]
    *** partially reqs: Raf1 and/or Braf [DRNAi]
    *** source: 16630891-Fig-7b
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: bAECs in BMLS
    *** does not req: Cav1 [RNAi]
    *** source: 15292187(D)
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: bAECs in BMLS
    *** does not req: Rac1 [RNAi]
    *** source: 15292187(D)
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: CCD18CO in BMLS
    *** reqs: Mlk3 [RNAi]
    *** source: 15258589-Fig-2a,3a,3c
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: CCL39 in BMLS "treated with serum for 3 hr"
    *** inhibited by: xDusp6 [addition]
    *** unaffected by: xDusp6(C293S) [addition]
    *** source: 9927426-Fig-1b
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: HEK293 in BMS
    *** does not req: Cab39 [RNAi]
    *** source: 14517248-Fig-10a
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: HELA in BMLS
    *** reqs: Erbb2 [RNAi]
    *** source: 16041367-Fig-3a
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: HELA in BMLS
    *** reqs: Phb [RNAi]
    *** source: 16041367-Fig-3a
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: HEPG2 in BMLS
    *** does not req: Braf [RNAi]
    *** does not req: Raf1 or Braf [DRNAi]
    *** source: 16630891-Fig-S1f
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: HEPG2 in BMLS
    *** partially reqs: Hras [RNAi]
    *** source: 16630891-Fig-S1f
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: HEPG2 in BMLS
    *** partially reqs: Kras [RNAi]
    *** source: 16630891-Fig-S1f
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: HEPG2 in BMLS
    *** partially reqs: Shoc2 [RNAi]
    *** source: 16630891-Fig-S1f
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: HEPG2 in BMLS
    *** reqs: Nras [RNAi]
    *** source: 16630891-Fig-S1f
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: HEPG2 in BMLS "Nras-CA-mutation"
    *** does not req: Raf1 [RNAi]
    *** does not req: Raf1 or Braf [DRNAi]
    *** source: 16630891-Fig-S1f
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: HEPG2 in BMLS "plated on collagen"
    *** partially inhibited by: Gefitinib [cotreatment]
    *** partially inhibited by: PD325901 [cotreatment]
    *** unaffected by: BMS345541 [cotreatment]
    *** unaffected by: PHA818637 [cotreatment]
    *** unaffected by: ZSTK474 [cotreatment]
    *** source: 19953085-Fig-S1
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: HPAF in BMLS
    *** does not req: Braf [RNAi]
    *** does not req: Raf1 or Braf [DRNAi]
    *** source: 16630891-Fig-S1b
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: HPAF in BMLS
    *** does not req: Nras [RNAi]
    *** reqs: Kras [RNAi]
    *** does not req: Raf1 [RNAi]
    *** does not req: Raf1 or Braf [DRNAi]
    *** source: 16630891-Fig-S1b
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: HPAF in BMLS
    *** does not req: Nras [RNAi]
    *** source: 16630891-Fig-S1b
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: HPAF in BMLS
    *** partially reqs: Hras [RNAi]
    *** source: 16630891-Fig-S1b
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: HPAF in BMLS
    *** partially reqs: Hras [RNAi]
    *** source: 16630891-Fig-S1b
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: HPAF in BMLS
    *** partially reqs: Shoc2 [RNAi]
    *** source: 16630891-Fig-S1b
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: HPAF in BMLS
    *** reqs: Kras [RNAi]
    *** source: 16630891-Fig-S1b
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: HPAF in BMLS "Kras-CA-mutation"
    *** does not req: Raf1 [RNAi]
    *** does not req: Raf1 or Braf [DRNAi]
    *** source: 16630891-Fig-S1b
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: HT1080 in BMLS
    *** does not req: Braf [RNAi]
    *** partially reqs: Raf1 and/or Braf [DRNAi]
    *** source: 16630891-Fig-S1e
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: HT1080 in BMLS
    *** partially reqs: Kras [RNAi]
    *** source: 16630891-Fig-S1e
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: HT1080 in BMLS
    *** partially reqs: Shoc2 [RNAi]
    *** source: 16630891-Fig-S1e
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: HT1080 in BMLS
    *** reqs: Hras [RNAi]
    *** source: 16630891-Fig-S1e
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: HT1080 in BMLS
    *** reqs: Nras [RNAi]
    *** source: 16630891-Fig-S1e
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: HT1080 in BMLS "Nras-CA-mutation"
    *** partially reqs: Raf1 [RNAi]
    *** partially reqs: Raf1 and/or Braf [DRNAi]
    *** source: 16630891-Fig-S1e
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: mBMMs in BMS
    *** reqs: Socs3 [KO]
    *** source: 12754506-Fig-4a
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: MCF7 in BMLS
    *** reqs: IqGap1 [RNAi]
    *** source: 16135787-Fig-4
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: MCF7 in BMS
    *** partially inhibited by: xIqGap1 [addition]
    *** reqs: IqGap1 [RNAi]
    *** source: 14970219-Fig-3a
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: MDAMB231 in BMLS
    *** does not req: Hras [RNAi]
    *** source: 16630891-Fig-S1c
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: MDAMB231 in BMLS
    *** does not req: Nras [RNAi]
    *** source: 16630891-Fig-S1c
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: MDAMB231 in BMLS
    *** partially reqs: Braf [RNAi]
    *** reqs: Raf1 and/or Braf [DRNAi]
    *** source: 16630891-Fig-S1c
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: MDAMB231 in BMLS
    *** partially reqs: Shoc2 [RNAi]
    *** source: 16630891-Fig-S1c
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: MDAMB231 in BMLS
    *** reqs: Kras [RNAi]
    *** source: 16630891-Fig-S1c
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: MDAMB231 in BMLS "Kras-CA-mutation"
    *** partially reqs: Raf1 [RNAi]
    *** reqs: Raf1 and/or Braf [DRNAi]
    *** source: 16630891-Fig-S1c
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: mEFs in BMLS
    *** does not req: Mnk1 and/or Mnk2 [DKO]
    *** source: 15254222-Fig-3a
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: mEFs in BMLS
    *** repressed by: Raf1 [KO]
    *** source: 11296228-Fig-6d
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: mEFs in BMLS
    *** repressed by: Raf1 [KO]
    *** source: 11296228-Fig-6e
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: mEFs in BMS
    *** inhibited by: PD184352 [addition]
    *** source: 15304344-Fig-4b
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: mEFs in BMS
    *** partially reqs: Rac1 [KO]
    *** source: 16698790-Fig-6a
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: mEFs in BMS
    *** unaffected by: SB203580 [addition]
    *** inhibited by: PD184352 [addition]
    *** inhibited by: SB203580 + PD184352 [addition]
    *** source: 15304344-Fig-5b
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: mEFs<Jnk1~null><Jnk2~null> in BMS
    *** inhibited by: PD184352 [addition]
    *** source: 15304344-Fig-4b
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: mEFs<Jnk1~null><Jnk2~null> in BMS
    *** inhibited by: PD184352 [addition]
    *** unaffected by: SB203580 [addition]
    *** inhibited by: SB203580 + PD184352 [addition]
    *** source: 15304344-Fig-5d
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: mEFs<Lamtor1~null><xLamtor1> in BMS
    *** partially reqs: xLamtor1 [omission]
    *** source: 19177150-Fig-6a
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: mESCs in BMLS
    *** does not req: Pdpk1 [KO]
    *** unaffected by: kPdpk1(L155E) [substitution]
    *** source: 12912918-Fig-5
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: mESCs in BMLS
    *** inhibited by: kPdpk1(L155E)"PIF" [knockin]
    *** source: 16763566-Fig-3b
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: mESCs in BMLS
    *** partially reqs: Pdpk1 [KO]
    *** source: 16763566-Fig-3a
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: MEWO in BMS
    *** partially inhibited by: Serum-depletion (tnr) [stress]
    *** source: 19274086-Fig-2b
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: MIAPACA2 in BMLS
    *** does not req: Braf [RNAi]
    *** does not req: Raf1 or Braf [DRNAi]
    *** source: 16630891-Fig-7a
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: MIAPACA2 in BMLS
    *** partially reqs: Hras [RNAi]
    *** source: 16630891-Fig-7a
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: MIAPACA2 in BMLS
    *** partially reqs: Nras [RNAi]
    *** source: 16630891-Fig-7a
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: MIAPACA2 in BMLS
    *** partially reqs: Shoc2 [RNAi]
    *** source: 16630891-Fig-7a
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: MIAPACA2 in BMLS
    *** reqs: Kras [RNAi]
    *** source: 16630891-Fig-7a
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: MIAPACA2 in BMLS "Kras-CA-mutation"
    *** does not req: Raf1 [RNAi]
    *** does not req: Raf1 or Braf [DRNAi]
    *** source: 16630891-Fig-7a
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: NIH3T3 in BMLS
    *** inhibited by: xHras(D57Y)"DN" [addition]
    *** source: 10327068-Fig-3a
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: PANC1 in BMLS
    *** does not req: Braf [RNAi]
    *** does not req: Raf1 or Braf [DRNAi]
    *** source: 16630891-Fig-7e
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: PANC1 in BMLS
    *** does not req: Nras [RNAi]
    *** source: 16630891-Fig-7e
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: PANC1 in BMLS
    *** partially reqs: Hras [RNAi]
    *** source: 16630891-Fig-7e
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: PANC1 in BMLS
    *** partially reqs: Kras [RNAi]
    *** source: 16630891-Fig-7e
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: PANC1 in BMLS
    *** partially reqs: Shoc2 [RNAi]
    *** source: 16630891-Fig-7e
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: PANC1 in BMLS "Kras-CA-mutation"
    *** does not req: Raf1 [RNAi]
    *** does not req: Raf1 or Braf [DRNAi]
    *** source: 16630891-Fig-7e
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: PC12<xGab1> in BMLS
    *** inhibited by: PD98059 [addition]
    *** unaffected by: LY294002 [addition]
    *** source: 10601297-Fig-9c
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: RAW2647 in BMLS "treated with Lps for 1 hr"
    *** does not req: Gsk3b [RNAi]
    *** source: 16537926-Fig-5e
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: RAW2647 in BMS
    *** inhibited by: PD184352 [addition]
    *** source: 12881422-Fig-4b
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: RD in BMLS
    *** does not req: Kras [RNAi]
    *** source: 16630891-Fig-S1d
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: RD in BMLS
    *** partially reqs: Braf [RNAi]
    *** reqs: Raf1 and/or Braf [DRNAi]
    *** source: 16630891-Fig-S1d
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: RD in BMLS
    *** partially reqs: Shoc2 [RNAi]
    *** source: 16630891-Fig-S1d
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: RD in BMLS
    *** reqs: Hras [RNAi]
    *** source: 16630891-Fig-S1d
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: RD in BMLS
    *** reqs: Nras [RNAi]
    *** source: 16630891-Fig-S1d
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: RD in BMLS "Nras-CA-mutation"
    *** partially reqs: Raf1 [RNAi]
    *** reqs: Raf1 and/or Braf [DRNAi]
    *** source: 16630891-Fig-S1d
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: SKMEL2 in BMLS
    *** does not req: Hras [RNAi]
    *** source: 16630891-Fig-7f
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: SKMEL2 in BMLS
    *** does not req: Kras [RNAi]
    *** source: 16630891-Fig-7f
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: SKMEL2 in BMLS
    *** partially reqs: Shoc2 [RNAi]
    *** source: 16630891-Fig-7f
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: SKMEL2 in BMLS
    *** reqs: Nras [RNAi]
    *** source: 16630891-Fig-7f
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: SKMEL2 in BMLS "Nras-CA-mutation"
    *** does not req: Braf [RNAi]
    *** reqs: Raf1 and/or Braf [DRNAi]
    *** source: 16630891-Fig-7f
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: SKMEL2 in BMLS "Nras-CA-mutation"
    *** reqs: Raf1 [RNAi]
    *** reqs: Raf1 and/or Braf [DRNAi]
    *** source: 16630891-Fig-7f
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: SKMEL28 in BMLS
    *** partially reqs: Braf [RNAi]
    *** comment: SKMEL28 contain Braf(V600E) mutation
    *** source: 19274086-Fig-3d
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: SKMEL28 in BMS
    *** partially reqs: Braf(V600E) [RNAi]
    *** source: 19187764-Fig-2a
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: SW480 in BMLS
    *** does not req: Braf [RNAi]
    *** does not req: Raf1 or Braf [DRNAi]
    *** source: 16630891-Fig-S1a
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: SW480 in BMLS
    *** does not req: Hras [RNAi]
    *** source: 16630891-Fig-S1a
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: SW480 in BMLS
    *** does not req: Nras [RNAi]
    *** source: 16630891-Fig-S1a
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: SW480 in BMLS
    *** partially reqs: Shoc2 [RNAi]
    *** source: 16630891-Fig-S1a
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: SW480 in BMLS
    *** reqs: Kras [RNAi]
    *** source: 16630891-Fig-S1a
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: SW480 in BMLS "Kras-CA-mutation"
    *** does not req: Raf1 [RNAi]
    *** does not req: Raf1 or Braf [DRNAi]
    *** source: 16630891-Fig-S1a
  *** Erks[phosAb] phos(TEY)[phosAb] is detectable
    *** cells: SWISS3T3 in BMS
    *** partially reqs: Shc1 [RNAi]
    *** source: 17673906-Fig-8e
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt anti-Itgav-adherence (60 min)
    *** cells: ECV304 in BMLS
    *** unaffected by: Egf (tnr) [stim]
    *** source: 18844239-Fig-2c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt anti-Itgb1-adherence (60 min)
    *** cells: ECV304 in BMLS
    *** unaffected by: Egf (tnr) [stim]
    *** source: 18844239-Fig-2c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itao Merlin [RNAi]
    *** cells: T29 in BMS
    *** source: 20890305-Fig-3c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itao Rin1 [RNAi]
    *** cells: HEPG2 in BMS
    *** source: 16457816-Fig-5a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itao Rin3 [RNAi]
    *** cells: HEPG2 in BMS
    *** source: 16457816-Fig-5a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo (xAraf + xMras(H81L)"CA")
    *** cells: HEK293T in BMS
    *** reqs: both [omissions]
    *** enhanced by: xShoc2 [addition]
    *** enhanced by: xAraf(S214A) [substitution]
    *** source: 16630891-Fig-4c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo (xAraf + xMras(H81L)"CA")
    *** cells: HEK293T in BMS
    *** reqs: both [omissions]
    *** enhanced by: xShoc2 [addition]
    *** source: 16630891-Fig-2c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo (xAraf + xMras(H81L)"CA")
    *** cells: HEK293T in BMS
    *** reqs: both [omissions]
    *** enhanced by: xShoc2 [addition]
    *** source: 16630891-Fig-3a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo (xMras(H81L)"CA" + xShoc2)
    *** cells: HEK293T in BMS
    *** reqs: both [omission]
    *** inhibited by: xMras(WT) [substitution]
    *** source: 16630891-Fig-3a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo (xMras(H81L)"CA" + xShoc2)
    *** cells: HEK293T in BMS
    *** reqs: both [omission]
    *** inhibited by: xMras(WT) [substitution]
    *** source: 16630891-Fig-4c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo (xMras(H81L)"CA" + xShoc2)
    *** cells: HEK293T in BMS
    *** reqs: both [omission]
    *** source: 16630891-Fig-2c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo (xMras(H81L)"CA" + xShoc2)
    *** cells: MCF7 in BMS
    *** reqs: xShoc2 [omission]
    *** inhibited by: xMras(H81L/D48A) [substitution]
    *** source: 16630891-Fig-2a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo (xMras(Q71L)"CA" + xAraf)
    *** cells: HEK293T in BMS
    *** reqs: both [omission]
    *** source: 15143186-Fig-1c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo (xMras(Q71L)"CA" + xRaf1)
    *** cells: HEK293T in BMS
    *** reqs: both [omission]
    *** source: 15143186-Fig-1c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo (xRaf1 + xMras(H81L)"CA")
    *** cells: HEK293T in BMS
    *** reqs: both [omission]
    *** enhanced by: xShoc2 [addition]
    *** source: 16630891-Fig-2c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo (xRaf1 + xMras(H81L)"CA")
    *** cells: HEK293T in BMS
    *** reqs: both [omission]
    *** enhanced by: xShoc2 [addition]
    *** unaffected by: xRaf1(S259A) [substitution]
    *** source: 16630891-Fig-4c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo (xRaf1 + xMras(H81L)"CA")
    *** cells: HEK293T in BMS
    *** reqs: both [omission]
    *** inhibited by: xMras(WT) [substitution]
    *** enhanced by: xShoc2 [addition]
    *** source: 16630891-Fig-3a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo (xRit1(Q79L)"CA" + xRaf1)
    *** cells: HEK293T in BMS
    *** reqs: both [omission]
    *** source: 15143186-Fig-1c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo (xRras2(G23V)"CA" + xRaf1)
    *** cells: HEK293T in BMS
    *** reqs: both [omission]
    *** source: 15143186-Fig-1c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo (xTak1 + xTab1)
    *** cells: HEK293 in BMS
    *** unaffected by: xKsr2 [addition]
    *** source: 16039990-Fig-1
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xBag1
    *** cells: OT23 in BMS
    *** inhibited by: xHspa1a [addition]
    *** unaffected by: xBag1(C204A) [substitution]
    *** unaffected by: xBag1(E208A) [substitution]
    *** source: 11231577-Fig-4a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xBraf
    *** cells: HEK293 in BMS
    *** enhanced by: xBraf(V600E) [substitution]
    *** enhanced by: xBraf(S365A) [substitution]
    *** inhibited by: xBraf(S729A) [substitution]
    *** inhibited by: xBraf(S365A/S729A) [substitution]
    *** source: 16702958-Fig-3c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xBraf
    *** cells: HEK293 in BMS
    *** enhanced by: xBraf(V600E) [substitution]
    *** enhanced by: xBraf(S365A) [substitution]
    *** unaffected by: xBraf(S365A/S446A/S447A) [substitution]
    *** unaffected by: xBraf(S365A/S446A/S447A/D448A/D449A) [substitution]
    *** source: 16702958-Fig-3c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xBraf
    *** cells: HEK293T in BMS
    *** source: 16630891-Fig-2c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xBraf
    *** cells: HEK293T in BMS
    *** unaffected by: xMras(H81L)"CA" [omission]
    *** unaffected by: xShoc2 [addition]
    *** source: 16630891-Fig-2c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xBraf
    *** cells: HEK293T<xMras> in BMS
    *** unaffected by: xBraf(S365A) [substitution]
    *** source: 16630891-Fig-3a,4c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xBraf
    *** cells: HEK293T<xMras> in BMS
    *** unaffected by: xShoc2 [addition]
    *** unaffected by: xMras(H81L)"CA" [addition]
    *** source: 16630891-Fig-3a,4c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xBraf(mnr)"CA"
    *** cells: NIH3T3<xFos> in BMS
    *** source: 12134156-Fig-5c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xBraf(mnr)"CA"
    *** cells: NIH3T3<xFos> in BMS
    *** unaffected by: xFos(S362A/S374A) [substitution]
    *** source: 12134156-Fig-5c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xBraf(V599E)"CA"
    *** cells: HTTA in BMLS
    *** source: 16005186-Fig-5
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xBraf(V599E)"CA"
    *** cells: HTTA in BMLS
    *** unaffected by: xRig1 [addition]
    *** unaffected by: xRig1(del(Cterm)) [addition]
    *** source: 16005186-Fig-5
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xBraf(V600E)
    *** cells: MCF10A in BMLS
    *** inhibited by: xBraf [substitution]
    *** inhibited by: xBraf(R188L) [substitution]
    *** unaffected by: xBraf(V600E/R118L) [substitution]
    *** inhibited by: xBraf(S446A/S5447A) [substitution]
    *** unaffected by: xBraf(V600E/S446A/S5447A) [substitution]
    *** inhibited by: xBraf(S365A/S446A/S447A/D448A/D449A) [substitution]
    *** unaffected by: xBraf(V600E/S365A/S446A/S447A/D448A/D449A) [substitution]
    *** inhibited by: xBraf(S365A) [substitution]
    *** source: 16702958-Fig-8a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xBraf(V600E)
    *** cells: MCF10A in BMLS
    *** inhibited by: xBraf [substitution]
    *** inhibited by: xBraf(S729A) [substitution]
    *** unaffected by: xBraf(V600E/S729A) [substitution]
    *** source: 16702958-Fig-8b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xFak1
    *** cells: MDCK in BMS
    *** source: 10713050-Fig-6a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xFrs2
    *** cells: HEK293<xFgfR1> in BMS
    *** unaffected by: xFrs2(Y196F/Y306F/Y349F/Y392F) [substitution]
    *** unaffected by: xFrs2(Y436F) [substitution]
    *** inhibited by: xFrs2(Y196F/Y306F/Y349F/Y392F/Y436F) [substitution]
    *** source: 9632781-Fig-4a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xGab1
    *** cells: PC12 in BMLS
    *** source: 10601297-Fig-4a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xHras(G12R)"CA"
    *** cells: NIH3T3 in BMLS
    *** source: 11340168-Fig-1a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xHras(G12V)
    *** cells: COS1 in BMLS
    *** unaffected by: xShp2(C459S) [addition]
    *** source: 14560030-Fig-1b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xHras(G12V)
    *** cells: HEK293T<xS6k1> in BMS
    *** enhanced by: AA-deprivation [pretreatment]
    *** source: 15854902-Fig-S1
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xHras(G12V)"CA"
    *** cells: COS<xRaf1> in BMS
    *** inhibited by: xHras(G12V/E37G) [substitution]
    *** source: 12077328-Fig-8b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xHras(G12V)"CA"
    *** cells: COS<xRaf1> in BMS
    *** partially inhibited by: xHras(G12V/E37G) [substitution]
    *** source: 12077328-Fig-4a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xHras(G12V)"CA"
    *** cells: COS<xRaf1> in BMS
    *** unaffected by: xRaf1(S257L) [substitution]
    *** unaffected by: xRaf1(S259A) [substitution]
    *** source: 12077328-Fig-4a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xHras(G12V)"CA"
    *** cells: HEK293 in BMS
    *** source: 12172553-Fig-1c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xHras(G12V)"CA"
    *** cells: HEK293 in BMS
    *** unaffected by: xTsc1 + xTsc2 [addition]
    *** source: 12172553-Fig-1c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xHras(G12V)"CA"
    *** cells: HEK293T in BMS
    *** source: 16630891-Fig-6a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xHras(G12V)"CA"
    *** cells: HELA in BMLS
    *** source: 9790194-Fig-2a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xHras(G12V)"CA"
    *** cells: HELA in BMS
    *** bkg inhibited by: xRho?(S19N)"DN" [addition]
    *** source: 11847220-Fig-1b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xHras(G12V)"CA"
    *** cells: NIH3T3<xInsR> in BMS
    *** source: 11046144-Fig-3b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xHras(G12V)"CA"
    *** cells: NotReported in BMS
    *** inhibited by: xBrap(C264A) [addition]
    *** unaffected by: xBrap [addition]
    *** source: 14724641-Fig-3c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xHras(G12V)"CA"
    *** cells: NotReported in BMS
    *** source: 14724641-Fig-3c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xHras(Q61L)
    *** cells: PC6 in BMLS
    *** source: 16157584-Fig-1e
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xHras(Q61L)"CA"
    *** cells: COS in BMLS
    *** enhanced by: xBraf [addition]
    *** unaffected by: xBraf(T599A/S602A) [addition]
    *** source: 15632082-Fig-5b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xHras(Q61L)"CA"
    *** cells: COS in BMS
    *** bkg inhibited by: PD98059 [addition]
    *** source: 15632082-Fig-1e
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xHras(Q61L)"CA"
    *** cells: HEK293 in BMS
    *** unaffected by: xKsr2 [addition]
    *** source: 16039990-Fig-1
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xHras(Q61L)"CA"
    *** cells: HEK293<xTsc1><xTsc2> in BMS
    *** inhibited by: xHras(S17N)"DN" [substitution]
    *** source: 15342917-Fig-1b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xHras(Q61L)"CA"
    *** cells: HEK293E in BMLS
    *** inhibited by: U0126 [pretreatment]
    *** source: 17360704-Fig-2c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xHras(Q61L)"CA"
    *** cells: HEK293E in BMLS
    *** inhibited by: xHras(S17N)"DN" [substitution]
    *** source: 17360704-Fig-2b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xHras(Q61L)"CA"
    *** cells: NIH3T3 in BMLS
    *** source: 10446149-Fig-5b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xHras(Q61L)"CA"
    *** cells: PC6 in BMLS
    *** source: 15632082-Fig-1c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xHras(Q61L)"CA"
    *** cells: PC6 in BMS
    *** bkg inhibited by: PD98059 [addition]
    *** source: 15632082-Fig-1f
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xKras(G12V)"CA"
    *** cells: HEK293T in BMS
    *** enhanced by: xRaf1 [addition]
    *** unaffected by: xBraf [addition]
    *** unaffected by: xAraf [addition]
    *** source: 15143186-Fig-1c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xKras(G12V)"CA"
    *** cells: HEK293T in BMS
    *** source: 16630891-Fig-6a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xMek?(mnr)"SDSE"
    *** cells: HELA in BMS
    *** does not req: IL17Rd [RNAi]
    *** source: 15239952-Fig-6c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xMek1(mnr)"CA"
    *** cells: HEK293 in BMS
    *** inhibited by: xMek1 [substitution]
    *** source: 16537926-Fig-2d
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xMek1(mnr)"CA"
    *** cells: HEK293<xTsc1><xTsc2> in BMS
    *** source: 15342917-Fig-1b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xMek1(mnr)"CA"
    *** cells: HEK293T<xIL2Rb><xJak3> in BMS
    *** source: 12435740-Fig-5d
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xMek1(S218D/S222D)
    *** cells: AKR2B in BMLS
    *** source: 23913859-Fig-3d
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xMek1(S281D/S222D)
    *** cells: HEK293 in BMS
    *** source: 15851026-Fig-1c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xMekk1
    *** cells: HEK293 in BMS
    *** unaffected by: xRgl3 [addition]
    *** source: 11313946-Fig-7
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xMekk3
    *** cells: HEK293 in BMS
    *** inhibited by: xKsr2 [addition]
    *** source: 16039990-Fig-1
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xMekk3
    *** cells: HEK293EBNA in BMS
    *** inhibited by: xMekk3(K391M)"KD" [substitution]
    *** inhibited by: xMekk3(S526A) [substitution]
    *** inhibited by: xMekk3(T530A) [substitution]
    *** unaffected by: xMekk3(T516A) [substitution]
    *** unaffected by: xMekk3(T528A) [substitution]
    *** unaffected by: xMekk3(T511A) [substitution]
    *** unaffected by: xMekk3(T520A) [substitution]
    *** unaffected by: xMekk3(T522A) [substitution]
    *** source: 16407301(D)
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xMekk3
    *** cells: HELA in BMS
    *** unaffected by: xBrap [addition]
    *** source: 14724641-Fig-2a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xMekk3(12-626)"CA"
    *** cells: HEK293T in BMS
    *** unaffected by: xMek5(mnr)"DN" [addition]
    *** source: 10593883-Fig-3
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xMras(H81L)"CA"
    *** cells: BT549 in BMS
    *** enhanced by: xShoc2 [addition]
    *** inhibited by: xMras(H81L/D48A) [substitution]
    *** source: 16630891-Fig-2a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xMras(H81L)"CA"
    *** cells: PAE in BMS
    *** enhanced by: xShoc2 [addition]
    *** inhibited by: xMras(H81L/D48A) [substitution]
    *** source: 16630891-Fig-2a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xNras(G12V)"CA"
    *** cells: HEK293T in BMS
    *** enhanced by: xRaf1 [addition]
    *** unaffected by: xBraf [addition]
    *** enhanced by: xAraf [addition]
    *** source: 15143186-Fig-1c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xNras(G12V)"CA"
    *** cells: HEK293T in BMS
    *** source: 16630891-Fig-6a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xPlce1
    *** cells: COS7 in BMLS
    *** unaffected by: xPlce1(1-1200)"Gef-domain" [substitution]
    *** source: 11395506-Fig-6
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xRaf1(305-648)"CA"
    *** cells: H197 in BMS
    *** inhibited by: PDB [pretreatment]
    *** inhibited by: Chelerythrine [pretreatment]
    *** unaffected by: Go6976 [pretreatment]
    *** inhibited by: Rottlerin [pretreatment]
    *** source: 10330161-Fig-5a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xRaf1(del(66-303))"CA"
    *** cells: HELA in BMS
    *** inhibited by: xBrap [addition]
    *** source: 14724641-Fig-2a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xRaf1(mnr)"BXB"
    *** cells: HELA in BMLS
    *** source: 9790194-Fig-2a
  *** xErks[phosAb] phos(TEY)[phosAb] is increased itpo xRaf1(mnr)"CA"
    *** cells: COS7<xSumo1> in BMS
    *** inhibited by: PD98059 [addition]
    *** source: 17897103-Fig-3b
  *** xErks[phosAb] phos(TEY)[phosAb] is increased itpo xRaf1(mnr)"CA"
    *** cells: COS7<xSumo1> in BMS
    *** source: 17897103-Fig-3a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xRaf1(S259A)"CA"
    *** cells: COS<xYwhaz> in BMS
    *** inhibited by: xRaf1(WT) [substitution]
    *** inhibited by: xRaf1(S259A/S621A) [substitution]
    *** source: 12077328-Fig-2c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xRaf1(S259A)"CA"
    *** cells: HEK293T in BMS
    *** inhibited by: xRaf1(WT) [substitution]
    *** partially inhibited by: xRaf1(S259A/S338A) [substitution]
    *** partially inhibited by: xRaf1(S259A/S338A/Y341F) [substitution]
    *** partially inhibited by: xRaf1(S259A/S338D) [substitution]
    *** enhanced by: xRaf1(S259A/S341D) [substitution]
    *** enhanced by: xRaf1(S259A/S338D/S341D) [substitution]
    *** enhanced by: xRaf1(S259A/T491E/S494D) [substitution]
    *** inhibited by: xRaf1(S338A) [substitution]
    *** inhibited by: xRaf1(S338A/Y341F) [substitution]
    *** inhibited by: xRaf1(S338D) [substitution]
    *** unaffected by: xRaf1(S341D) [substitution]
    *** unaffected by: xRaf1(S338D/S341D) [substitution]
    *** unaffected by: xRaf1(T491E/S494D) [substitution]
    *** enhanced by: xRaf1(S338D/S341D/T491E/S494D) [substitution]
    *** source: 16630891-Fig-4d
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xRaf1(S259A)"CA"
    *** cells: HEK293T in BMS
    *** unaffected by: xShoc2 [addition]
    *** source: 16630891-Fig-4c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xRanbp9
    *** cells: HELA in BMLS
    *** inhibited by: xHras(mnr)"DN" [addition]
    *** source: 12147692-Fig-2d
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xRapGef2
    *** cells: COS7 in BMLS
    *** source: 11395506-Fig-6
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xRin1(Q78L)
    *** cells: PC6<xBraf> in BMLS
    *** inhibited by: PD98059 [pretreatment]
    *** source: 16157584-Fig-6g
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xRin1(Q78L)
    *** cells: PC6<xBraf> in BMLS
    *** reqs: xBraf [omission]
    *** source: 16157584-Fig-6f
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xRin1(Q78L)
    *** cells: PC6<xBraf> in BMLS
    *** reqs: xBraf [omission]
    *** source: 16157584-Fig-6g
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xRin1(Q78L)
    *** cells: PC6<xBraf> in BMLS
    *** unaffected by: SB203580 [pretreatment]
    *** source: 16157584-Fig-6f
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xRit1(Q79L)"CA"
    *** cells: COS in BMLS
    *** enhanced by: xBraf [addition]
    *** partially inhibited by: xBraf(T599A/S602A) [addition]
    *** source: 15632082-Fig-5b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xRit1(Q79L)"CA"
    *** cells: COS in BMS
    *** bkg inhibited by: PD98059 [addition]
    *** source: 15632082-Fig-1e
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xRit1(Q79L)"CA"
    *** cells: PC6 in BMLS
    *** inhibited by: xRit1(WT) [substitution]
    *** source: 15632082-Fig-1c
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xRit1(Q79L)"CA"
    *** cells: PC6 in BMS
    *** bkg inhibited by: PD98059 [addition]
    *** source: 15632082-Fig-1f
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xRras2(G23V)"CA"
    *** cells: NIH3T3 in BMLS
    *** bkg inhibited by: U0126 [addition]
    *** unaffected by: LY294002 [addition]
    *** inhibited by: xRras2(G23V/E48G) [substitution]
    *** inhibited by: xRras2(G23V/E46S) [substitution]
    *** unaffected by: xRras2(G23V/Y51C) [substitution]
    *** source: 11340168-Fig-1a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xTpl2
    *** cells: RAW2647 in BMS
    *** source: 12234923-Fig-2b
  *** Erks[phosAb] phos(TEY)[phosAb] is increased itpo xUbiq
    *** cells: U2OS<Ubiq~null> in BMS
    *** inhibited by: xUbiq(K63R) [substitution]
    *** source: 19854138-Fig-S3e
  *** Erks[phosAb] phos(TEY)[phosAb] is unchanged irt Glucose-deprivation (4 hr)
    *** cells: A375 in BMLS
    *** source: 19274086-Fig-3a
  *** Erks[phosAb] phos(TEY)[phosAb] is unchanged itao Ppp2r1a [RNAi]
    *** cells: PC63 in BMHIS
    *** source: 16129692-Fig-1a
  *** Erks[phosAb] phos(TEY)[phosAb] is unchanged itao Rin2 [RNAi]
    *** cells: HEPG2 in BMS
    *** source: 16457816-Fig-5a
  *** Erks[phosAb] phos(TEY)[phosAb] is unchanged itpo (xArf4(Q71L)"CA" + xPld2) 
    *** cells: HEK293T<xEgfR> in BMLS
    *** source: 12446727-Fig-7
  *** Erks[phosAb] phos(TEY)[phosAb] is unchanged itpo xAraf
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1c
  *** Erks[phosAb] phos(TEY)[phosAb] is unchanged itpo xBraf
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1c
  *** Erks[phosAb] phos(TEY)[phosAb] is unchanged itpo xFgfR1
    *** cells: HEK293 in BMS
    *** source: 9632781-Fig-4a
  *** Erks[phosAb] phos(TEY)[phosAb] is unchanged itpo xMatk
    *** cells: PC12 in BMLS
    *** source: 10329710-Fig-6b
  *** xErks[phosAb] phos(TEY)[phosAb] is unchanged itpo xMek1(mnr)"CA"
    *** cells: COS7<xSumo1> in BMS
    *** source: 17897103-Fig-3a
  *** Erks[phosAb] phos(TEY)[phosAb] is unchanged itpo xMek5(mnr)"CA"
    *** cells: HEK293T<xEgfR> in BMLS
    *** source: 12446727-Fig-7
  *** Erks[phosAb] phos(TEY)[phosAb] is unchanged itpo xMek5(mnr)"CA"
    *** cells: HELA in BMLS
    *** source: 9790194-Fig-2a
  *** Erks[phosAb] phos(TEY)[phosAb] is unchanged itpo xMekk4
    *** cells: HEK293 in BMS
    *** source: 16039990-Fig-1
  *** xErks[phosAb] phos(TEY)[phosAb] is unchanged itpo xMkk6(mnr)"CA"
    *** cells: COS7<xSumo1> in BMS
    *** source: 17897103-Fig-3a
  *** xErks[phosAb] phos(TEY)[phosAb] is unchanged itpo xMkk6(mnr)"CA"
    *** cells: COS7<xSumo1> in BMS
    *** source: 17897103-Fig-3b
  *** Erks[phosAb] phos(TEY)[phosAb] is unchanged itpo xMras(Q71L)"CA"
    *** cells: HEK293T in BMS
    *** unaffected by: xBraf [addition]
    *** source: 15143186-Fig-1c
  *** Erks[phosAb] phos(TEY)[phosAb] is unchanged itpo xPak1(T423E)"CA"
    *** cells: mEFs in BMS
    *** source: 16698790-Fig-6b
  *** Erks[phosAb] phos(TEY)[phosAb] is unchanged itpo xRaf1
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1c
  *** Erks[phosAb] phos(TEY)[phosAb] is unchanged itpo xRala(Q61L)"CA"
    *** cells: HEK293 in BMLS
    *** source: 10675331-Fig-5c
  *** Erks[phosAb] phos(TEY)[phosAb] is unchanged itpo xRap1a(G12V)"CA"
    *** cells: HEK293T in BMS
    *** unaffected by: xRaf1 [addition]
    *** unaffected by: xBraf [addition]
    *** unaffected by: xAraf [addition]
    *** source: 15143186-Fig-1c
  *** Erks[phosAb] phos(TEY)[phosAb] is unchanged itpo xRap1b(G12V)
    *** cells: HEK293T<xS6k1> in BMS
    *** unaffected by: AA-deprivation [pretreatment]
    *** source: 15854902-Fig-S1
  *** Erks[phosAb] phos(TEY)[phosAb] is unchanged itpo xRap2a(G12V)"CA"
    *** cells: HEK293T in BMS
    *** unaffected by: xRaf1 [addition]
    *** unaffected by: xBraf [addition]
    *** unaffected by: xAraf [addition]
    *** source: 15143186-Fig-1c
  *** Erks[phosAb] phos(TEY)[phosAb] is unchanged itpo xRgl2(mnr)"CAAX"
    *** cells: mEFs<Jnk1~null><Jnk2~null> in BMLS
    *** source: 12110590-Fig-5f
  *** Erks[phosAb] phos(TEY)[phosAb] is unchanged itpo xRgl2(mnr)"CAAX"
    *** cells: NIH3T3<xInsR> in BMLS
    *** source: 12110590-Fig-5f
  *** Erks[phosAb] phos(TEY)[phosAb] is unchanged itpo xRgl2(mnr)"CAAX"
    *** cells: NIH3T3<xInsR> in BMS
    *** source: 11046144-Fig-3b
  *** Erks[phosAb] phos(TEY)[phosAb] is unchanged itpo xRheb
    *** cells: HEK293E in BMLS
    *** source: 12906785-Fig-1c
  *** Erks[phosAb] phos(TEY)[phosAb] is unchanged itpo xRheb
    *** cells: HEK293T<xS6k1> in BMS
    *** unaffected by: AA-deprivation [pretreatment]
    *** source: 15854902-Fig-S1
  *** Erks[phosAb] phos(TEY)[phosAb] is unchanged itpo xRheb(Q64L)"CA"
    *** cells: HEK293T in BMS
    *** unaffected by: xBraf [addition]
    *** unaffected by: xRaf1 [addition]
    *** unaffected by: xAraf [addition]
    *** source: 15143186-Fig-1c
  *** Erks[phosAb] phos(TEY)[phosAb] is unchanged itpo xRhoa(Q63L)"CA"
    *** cells: HEK293T in BMLS
    *** source: 11598209-Fig-7c
  *** Erks[phosAb] phos(TEY)[phosAb] is unchanged itpo xRin1(A78L)"CA"
    *** cells: HEK293T in BMS
    *** unaffected by: xRaf1 [addition]
    *** unaffected by: xBraf [addition]
    *** unaffected by: xAraf [addition]
    *** source: 15143186-Fig-1c
  *** Erks[phosAb] phos(TEY)[phosAb] is unchanged itpo xRin1(Q78L)
    *** cells: PC6 in BMLS
    *** comment: a slight bit of phos can be seen if Erks are IPed first
    *** source: 16157584-Fig-1e
  *** Erks[phosAb] phos(TEY)[phosAb] is unchanged itpo xRin1(Q78L)
    *** cells: PC6 in BMLS
    *** source: 16157584-Fig-1d
  *** Erks[phosAb] phos(TEY)[phosAb] is unchanged itpo xRit1(Q79L)"CA"
    *** cells: HEK293T in BMS
    *** unaffected by: xBraf [addition]
    *** unaffected by: xAraf [addition]
    *** source: 15143186-Fig-1c
  *** Erks[phosAb] phos(TEY)[phosAb] is unchanged itpo xRock1
    *** cells: mEFs in BMS
    *** source: 16698790-Fig-6b
  *** Erks[phosAb] phos(TEY)[phosAb] is unchanged itpo xRras(G38V)"CA"
    *** cells: COS<xRaf1> in BMS
    *** source: 12077328-Fig-8b
  *** Erks[phosAb] phos(TEY)[phosAb] is unchanged itpo xRras(G38V)"CA"
    *** cells: HEK293T in BMS
    *** unaffected by: xRaf1 [addition]
    *** unaffected by: xBraf [addition]
    *** unaffected by: xAraf [addition]
    *** source: 15143186-Fig-1c
  *** Erks[phosAb] phos(TEY)[phosAb] is unchanged itpo xRras2(G23V)"CA"
    *** cells: COS<xRaf1> in BMS
    *** source: 12077328-Fig-8b
  *** Erks[phosAb] phos(TEY)[phosAb] is unchanged itpo xRras2(G23V)"CA"
    *** cells: HEK293T in BMS
    *** unaffected by: xBraf [addition]
    *** unaffected by: xAraf [addition]
    *** source: 15143186-Fig-1c
  *** Erks[phosAb] phos(TEY)[phosAb] is unchanged itpo xRsk1
    *** cells: HEK293E in BMLS
    *** source: 12906785-Fig-1c
  *** Erks[phosAb] phos(TEY)[phosAb] is undetectable
    *** cells: 3731E in BMLS "Low-Glucose"
    *** unaffected by: U0126 [addition]
    *** source: 19274086-Fig-3a
  *** Erks[phosAb] phos(TPY)[phosAb] is increased itpo xTab1
    *** cells: HEK293T<xTak1><xUbiq(K63only)> in BMS
    *** inhibited by: xTak1(K158R) [substitution]
    *** unaffected by: xTak1(K34R) [substitution]
    *** source: 20837137-Fig-2
  *** Eselectin-gene promo-reporter[Luc] is increased itpo xIkk1
    *** cells: HELA in BMS
    *** inhibited by: xIkk1(S176A) [substitution]
    *** inhibited by: xIkk1(K44A)"KD" [substitution]
    *** source: 9520446-Fig-4c
  *** Eselectin-gene promo-reporter[Luc] is increased itpo xIrak1
    *** cells: HEK293I1A<Irak1~null> in BMS
    *** reqs: xIrak1 [omission]
    *** source: 11960013-Fig-4b
  *** Eselectin-gene promo-reporter[Luc] is increased itpo xMyd88
    *** cells: HEK293 in BMS
    *** source: 12496252-Fig-4a
  *** Eselectin-gene promo-reporter[Luc] is increased itpo xPeli1
    *** cells: HEK293 in BMS
    *** inhibited by: xTak1(K66W)"DN" [addition]
    *** source: 12496252-Fig-4b
  *** Eselectin-gene promo-reporter[Luc] is increased itpo xPeli1
    *** cells: HEK293 in BMS
    *** source: 12496252-Fig-4a
  *** Eselectin-gene promo-reporter[Luc] is increased itpo xPeli1
    *** cells: HEK293I1A<Irak1~null> in BMS
    *** source: 12496252-Fig-4a
  *** Eselectin-gene promo-reporter[Luc] is increased itpo xTak1
    *** cells: HEK293 in BMS
    *** does not req: Peli1 [RNAi]
    *** source: 12496252-Fig-4c
  *** Eselectin-gene promo-reporter[Luc] is unchanged itpo xIrak4
    *** cells: HEK293I1A<Irak1~null> in BMS
    *** reqs: xIrak1 [omission]
    *** source: 11960013-Fig-4b
  *** Eselectin-gene promo-reporter[Luc] is unchanged itpo xMyd88
    *** cells: HEK293I1A<Irak1~null> in BMS
    *** source: 12496252-Fig-4a
  *** Ets-reporter[Luc] is increased itpo xEts1
    *** cells: mESCs in BMS
    *** enhanced by: xMek1(mnr)"CA" [addition]
    *** does not req: Med23 [KO]
    *** source: 11934987-Fig-3a
  *** Ets-reporter[Luc] is increased itpo xMek1(mnr)"CA"
    *** cells: mESCs<xEts1> in BMS
    *** reqs: Med23 [KO]
    *** source: 11934987-Fig-3a
  *** rEts1[35S] boundby[WB] rEts2[GST] is detectable
    *** cells: none
    *** enhanced by: xFos [addition]
    *** source: 9334186-Fig-1a
  *** Ets1[Ab] boundto(Cdc11a-gene)[ChIP] is detectable
    *** cells: HCT116 in BMS
    *** source: 15498926-Fig-4a
  *** Ets1[Ab] boundto(Cdc11a-gene)[ChIP] is detectable
    *** cells: JURKAT<Pten~null> in BMS
    *** source: 15498926-Fig-4a
  *** Ets1[Ab] boundto(Egr1-gene)[ChIP] is undetectable
    *** cells: HCT116 in BMS
    *** source: 15498926-Fig-4a
  *** Ets1[Ab] boundto(Egr1-gene)[ChIP] is undetectable
    *** cells: JURKAT<Pten~null> in BMS
    *** source: 15498926-Fig-4a
  *** Ets2[Ab] boundto(Cdc11a-gene)[ChIP] is detectable
    *** cells: HCT116 in BMS
    *** source: 15498926-Fig-4a
  *** Ets2[Ab] boundto(Cdc11a-gene)[ChIP] is detectable
    *** cells: JURKAT<Pten~null> in BMS
    *** source: 15498926-Fig-4a
  *** Ets2[Ab] boundto(Egr1-gene)[ChIP] is undetectable
    *** cells: HCT116 in BMS
    *** source: 15498926-Fig-4a
  *** Ets2[Ab] boundto(Egr1-gene)[ChIP] is undetectable
    *** cells: JURKAT<Pten~null> in BMS
    *** source: 15498926-Fig-4a
  *** Ets12s[Ab] boundto(Cdc11a-gene)[ChIP] is detectable
    *** cells: HCT116 in BMS
    *** source: 15498926-Fig-4a
  *** Ets12s[Ab] boundto(Cdc11a-gene)[ChIP] is detectable
    *** cells: JURKAT<Pten~null> in BMS
    *** source: 15498926-Fig-4a
  *** Ets12s[Ab] boundto(Egr1-gene)[ChIP] is undetectable
    *** cells: HCT116 in BMS
    *** source: 15498926-Fig-4a
  *** Ets12s[Ab] boundto(Egr1-gene)[ChIP] is undetectable
    *** cells: JURKAT<Pten~null> in BMS
    *** source: 15498926-Fig-4a
  *** Etv5-gene mRNA[Northern] is detectable
    *** cells: mSpTh1 in BMS
    *** source: 10097133-Fig-2b
  *** Etv5-gene mRNA[Northern] is undetectable
    *** cells: mSpTh2 in BMS
    *** source: 10097133-Fig-2b
*** Fadd--
  *** Fadd[Ab] snaggedby[WB] rTradd[GST] is detectable
    *** cells: HELA in BMS "treated with Tnf (30 min)"
    *** unaffected by: rStat1 [addition]
    *** source: 10848577-Fig-4b
  *** xFadd[tAb] copptby[WB] xFasR[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 8565075-Fig-5b
  *** xFadd[tAb] copptby[WB] xMavs[Ab] is undetectable
    *** cells: HEK293 in BMS
    *** source: 16125763-Fig-S5a
  *** xFadd[tAb] copptby[WB] xMavs[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 16127453-Fig-5c
  *** xFadd[tAb] copptby[WB] xMavs[tAb] is increased itpo xRipk1
    *** cells: HEK293T in BMS
    *** source: 18439848-Fig-4d
  *** xFadd[tAb] copptby[WB] xMavs[tAb] is increased itpo xTradd
    *** cells: HEK293T in BMS
    *** source: 18439848-Fig-4d
  *** xFadd[tAb] copptby[WB] xNod1[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 10329646(D)
  *** xFadd[tAb] copptby[WB] xTnfR1[Ab] is increased itpo xTradd
    *** cells: HEK293 in BMS
    *** enhanced by: xTraf1 + xTraf2 [addition]
    *** source: 8565075-Fig-5b
  *** xFadd[tAb] copptby[WB] xTnfR1[Ab] is undetectable
    *** cells: HEK293 in BMS
    *** source: 8565075-Fig-5b
  *** rFak1(398-414) phos(Y407)[phosAb] is increased by rFak2{act}
    *** cells: none
    *** source: 16761434-Fig-7e
  *** xFak1(K454A)[Ab]IP phos[32P-ATP] is increased itpo xFak2
    *** cells: HEK293T in BMS
    *** source: 10085136-Fig-3c
  *** xFak1(K454A)[Ab]IP Yphos[pYAb] is increased itpo xFak2
    *** cells: HEK293T in BMS
    *** source: 10085136-Fig-3a
  *** xFak1(K454A)[Ab]IP Yphos[pYAb] is increased itpo xFak2
    *** cells: HEK293T in BMS
    *** unaffected by: xFak1(Y397F) [substitution]
    *** unaffected by: xFak1(Y576F/Y577F) [substitution]
    *** unaffected by: xFak1(Y925F) [substitution]
    *** source: 10085136-Fig-6
  *** xFak1(K454A)[Ab]IP Yphos[pYAb] is unchanged itpo xLck
    *** cells: HEK293T in BMS
    *** source: 10085136-Fig-2b
  *** Fak1[Ab] copptby[WB] Apc[Ab] is detectable
    *** cells: HELAS3 in BMS
    *** source: 20224554-Fig-5f
  *** Fak1[Ab] copptby[WB] Crk[Ab] is detectable
    *** cells: T47D in BMS
    *** source: 7561682-Fig-1a
  *** Fak1[Ab] copptby[WB] Ctnnd1[Ab] is undetectable
    *** cells: A431 in BMS
    *** unaffected by: Egf (5 min) [stim]
    *** source: 7623846-Fig-2
  *** Fak1[Ab] copptby[WB] Dvls[Ab] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xApc(221-958) [addition]
    *** source: 20224554-Fig-S16c
  *** Fak1[Ab] copptby[WB] Dvls[Ab] is detectable
    *** cells: HELAS3 in BMS
    *** source: 20224554-Fig-5e
  *** Fak1[Ab] copptby[WB] Erks[Ab] is undetectable
    *** cells: HEK293 in BMS
    *** source: 15851026-Fig-2b
  *** Fak1[Ab] copptby[WB] Fer[Ab] is undetectable
    *** cells: A431 in BMS
    *** unaffected by: Egf (5 min) [stim]
    *** source: 7623846-Fig-2
  *** Fak1[Ab] copptby[WB] Pten[Ab] is detectable
    *** cells: HT29 in BMS
    *** source: 11857088-Fig-6
  *** Fak1[Ab] copptby[WB] Pxn[Ab] is detectable
    *** cells: HPBALL in BMS "plated on Fn1"
    *** source: 7561682-Fig-1a
  *** Fak1[Ab] copptby[WB] Pxn[Ab] is detectable
    *** cells: HPBALL in BMS "plated on uncoated surface"
    *** source: 7561682-Fig-1a
  *** Fak1[Ab] copptby[WB] Pxn[Ab] is detectable
    *** cells: T47D in BMS
    *** source: 7561682-Fig-1a
  *** Fak1[Ab] copptby[WB] Src[Ab] is detectable
    *** cells: mEFs in BMS
    *** reqs: Rac1 [KO]
    *** source: 16698790-Fig-1a
  *** Fak1[Ab] copptby[WB] Tns3[Ab] is detectable
    *** cells: MDAMB468 in BMLS
    *** source: 15140944-Fig-5a
  *** Fak1[Ab] snaggedby[WB] Grb2[GST] is detectable
    *** cells: mEFs in BMS
    *** does not req: Ptpn12 [KO]
    *** source: 10085298-Fig-6
  *** Fak1[Ab] snaggedby[WB] rPak1[GST] is undetectable
    *** cells: 3Y1 in BMS
    *** source: 11096073-Fig-1a
  *** Fak1[Ab] snaggedby[WB] rPak3[GST] is undetectable
    *** cells: 3Y1 in BMS
    *** source: 11096073-Fig-1a
  *** xFak1[Ab] snaggedby[WB] rPtpn12((1-301)/C231S)[GST] is undetectable
    *** cells: HEK293 in BMS "treated with pervanadate"
    *** unaffected by: rPtpn12(1-301) [substitution]
    *** source: 11337490-Fig-1b
  *** Fak1[Ab] snaggedby[WB] rPxn(mnr)"Nterm"[GST] is detectable
    *** cells: MIMCD3 in BMLS
    *** enhanced by: rPxn(mnr)"Nterm"{phos} [substitution]
    *** comment: rPxn was phosed with pErks{act}
    *** source: 11784715-Fig-4b
  *** Fak1[Ab] snaggedby[WB] rPxn[GST] is detectable
    *** cells: HELA in BMS
    *** source: 9054445-Fig-3a
  *** Fak1[Ab] snaggedby[WB] rPxn[GST] is detectable
    *** cells: U937 in BMS
    *** source: 9054445-Fig-3a
  *** Fak1[Ab]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: mEFs<Src~null><xSrc> in BMLS
    *** reqs: Src [KO]
    *** source: 9032297-Fig-2b
  *** xFak1[Ab]IP IVKA(auto)[32P-ATP] is increased itpo xFak2
    *** cells: HEK293T in BMS
    *** source: 10085136-Fig-4a
  *** xFak1[Ab]IP IVKA(peptide)[32P-ATP] is increased itpo xFak2
    *** cells: HEK293T in BMS
    *** source: 10085136-Fig-4a
  *** xFak1[Ab]IP IVKA(Pxn)[32P-ATP] is detectable
    *** cells: HEK293<xFak1> in BMS "treated with pervanadate"
    *** comment: unaffected by addition of rPtpn12(1-301) to lysates
    *** source: 11337490-Fig-7c
  *** xFak1[Ab]IP IVKA(Pxn)[32P-ATP] is unchanged itpo xPtpn12
    *** cells: HEK293<xFak1> in BMS "treated with pervanadate"
    *** source: 11337490-Fig-7d
  *** Fak1[Ab]IP Yphos[pYAb] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: xPtpn12 [addition]
    *** source: 11337490-Fig-3c
  *** xFak1[Ab]IP Yphos[pYAb] is detectable
    *** cells: HEK293<xFak1> in BMS
    *** partially inhibited by: xPtpn12 [addition]
    *** source: 11337490-Fig-3a
  *** xFak1[Ab]IP Yphos[pYAb] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xFak2(691-1009)"CRNK" [addition]
    *** inhibited by: xFak1(693-1052)"FRNK" [addition]
    *** source: 10085136-Fig-7b
  *** Fak1[Ab]IP Yphos[pYAb] is detectable
    *** cells: MDAMB468 in BMLS
    *** source: 15140944-Fig-5b
  *** Fak1[Ab]IP Yphos[pYAb] is detectable
    *** cells: mEFs<Src~null><xSrc> in BMLS
    *** does not req: Src [KO]
    *** source: 9032297-Fig-1b
  *** xFak1[Ab]IP Yphos[pYAb] is increased itpo xFak2
    *** cells: HEK293T in BMS
    *** source: 10085136-Fig-4b
  *** xFak1[Ab]IP Yphos[pYAb] is increased itpo xFak2
    *** cells: HEK293T in BMS
    *** source: 10085136-Fig-5a
  *** Fak1[Ab]IP Yphos[pYAb] is unchanged itpo xPtk6
    *** cells: COS1 in BMLS
    *** source: 15572663-Fig-1c
  *** Fak1[phosAb] phos(Y397)[phosAb] is increased itpo xMek1(mnr)"CA"
    *** cells: hTECs in BMLS "plated on gelatin for 4 hr"
    *** source: 18032789-Fig-5b
  *** Fak1[phosAb] phos(Y407)[phosAb] is detectable
    *** cells: hUVECs in BMLS
    *** reqs: Fak2 [RNAi]
    *** source: 16761434-Fig-7c
  *** Fak1[phosAb] phos(Y407)[phosAb] is detectable
    *** cells: hUVECs<xFak2> in BMLS
    *** inhibited by: xFak2(Y402F) [substitution]
    *** source: 16761434-Fig-7b
  *** Fak1[phosAb] phos(Y576/Y577)[phosAb] is unchanged itpo xCrk
    *** cells: HEK293T in BMS
    *** unaffected by: xGab1 [addition]
    *** unaffected by: xGab1(del(241-411)) [addition]
    *** source: 19350053-Fig-S10
  *** Fak1[phosAb] phos(Y576/Y577)[phosAb] is unchanged itpo xGab1
    *** cells: HEK293T in BMS
    *** unaffected by: xGab1(del(241-411)) [substitution]
    *** source: 19350053-Fig-S10
  *** xFak1[tAb] copptby[WB] Bcar1[Ab] is detectable
    *** cells: COS7 in BMS
    *** source: 10739664-Fig-5
  *** xFak1[tAb] copptby[WB] xPxn[tAb] is detectable
    *** cells: CHOK1 in BMS
    *** unaffected by: xPxn(S273A) [substitution]
    *** unaffected by: xPxn(S273D) [substitution]
    *** source: 16717130-Fig-1d
  *** xFak1[tAb]IP phos(S732)[phosAb] is detectable
    *** cells: hUVECs<xFak1> in BMLS
    *** reqs: Rock1 [RNAi]
    *** source: 16761434-Fig-5e
  *** xFak1[tAb]IP phos(Y407)[phosAb] is detectable
    *** cells: hUVECs<xFak1> in BMLS
    *** inhibited by: xFak1(S732A) [substitution]
    *** source: 16761434-Fig-3b
  *** xFak1[tAb]IP Yphos[pYAb] is decreased itpo xPtprh
    *** cells: HEK293 in BMS
    *** reversed by: rPtprh(C1022S)"CIA" [substitution]
    *** reversed by: rPtprh(D988A)"CIA" [substitution]
    *** source: 11278335-Fig-3a
  *** xFak1[tAb]IP Yphos[pYAb] is detectable
    *** cells: MDCK<xFak1> in BMS
    *** unaffected by: xFak1(D395A) [substitution]
    *** unaffected by: xFak1(P712A/P715A) [substitution]
    *** partially inhibited by: xFak1(Y925F) [substitution]
    *** source: 10713050-Fig-1b
  *** xFak2(K457A)[Ab]IP Yphos[pYAb] is unchanged itpo xFak1
    *** cells: HEK293T in BMS
    *** source: 10085136-Fig-3b
  *** xFak2(K457A)[Ab]IP Yphos[pYAb] is unchanged itpo xLck
    *** cells: HEK293T in BMS
    *** source: 10085136-Fig-2a
  *** Fak2[Ab] snaggedby[WB] rPtpn12((1-301)/C231S)[GST] is detectable
    *** cells: A7R5 in BMS "treated with pervanadate"
    *** inhibited by: rPtpn12(1-301) [substitution]
    *** source: 11337490-Fig-1c
  *** xFak2[Ab] snaggedby[WB] rPtpn12((1-301)/C231S)[GST] is detectable
    *** cells: HEK293<xFak2> in BMS "treated with pervanadate"
    *** inhibited by: rPtpn12(1-301) [substitution]
    *** source: 11337490-Fig-1a
  *** xFak2[Ab] snaggedby[WB] rPtpn12((1-301)/C231S)[GST] is detectable
    *** cells: HEK293<xFak2> in BMS "treated with pervanadate"
    *** inhibited by: rPtpn12(1-301) [substitution]
    *** source: 11337490-Fig-4
  *** xFak2[Ab] snaggedby[WB] rPtpn12((1-301)/C231S)[GST] is detectable
    *** cells: HEK293<xFak2> in BMS "treated with pervanadate"
    *** partially inhibited by: xFak2(Y402F) [substitution]
    *** inhibited by: xFak2(Y579F/Y580F) [substitution]
    *** unaffected by: xFak2(Y881F) [substitution]
    *** source: 11337490-Fig-4
  *** xFak2[Ab]IP IVKA(Pxn)[32P-ATP] is decreased itpo xPtpn12
    *** cells: HEK293<xFak2> in BMS "treated with pervanadate"
    *** source: 11337490-Fig-7d
  *** xFak2[Ab]IP IVKA(Pxn)[32P-ATP] is detectable
    *** cells: HEK293<xFak2> in BMS "treated with pervanadate"
    *** comment: inhibited by addition of rPtpn12(1-301) to lysates
    *** source: 11337490-Fig-7a
  *** xFak2[Ab]IP IVKA(Pxn)[32P-ATP] is detectable
    *** cells: HEK293<xFak2> in BMS "treated with pervanadate"
    *** inhibited by: xFak2(Y579F/Y580F) [substitution]
    *** source: 11337490-Fig-7a
  *** xFak2[Ab]IP phos(Y402)[phosAb] is decreased by rPtpn12(1-301)
    *** cells: none
    *** IPfrom: HEK293<xFak2> in BMS "treated with pervanadate"
    *** source: 11337490-Fig-6a
  *** xFak2[Ab]IP phos(Y402)[phosAb] is detectable
    *** cells: HEK293<xFak2> in BMS "treated with pervanadate"
    *** inhibited by: xFak2(Y402F) [substitution]
    *** partially inhibited by: xFak2(Y579F/Y580F) [substitution]
    *** source: 11337490-Fig-5b
  *** xFak2[Ab]IP phos(Y579/Y580)[phosAb] is decreased by rPtpn12(1-301)
    *** cells: none
    *** IPfrom: HEK293<xFak2> in BMS "treated with pervanadate"
    *** source: 11337490-Fig-6a
  *** xFak2[Ab]IP phos(Y579/Y580)[phosAb] is detectable
    *** cells: HEK293<xFak2> in BMS "treated with pervanadate"
    *** partially inhibited by: xFak2(Y402F) [substitution]
    *** inhibited by: xFak2(Y579F/Y580F) [substitution]
    *** source: 11337490-Fig-5c
  *** xFak2[Ab]IP Yphos[pYAb] is decreased by rPtpn12(1-301)
    *** cells: none
    *** IPfrom: HEK293<xFak2> in BMS "treated with pervanadate"
    *** source: 11337490-Fig-6a
  *** xFak2[Ab]IP Yphos[pYAb] is decreased itpo xPtpn12
    *** cells: HEK293<xFak2> in BMS
    *** unaffected by: xPtpn12(del(367-400)) [substitution]
    *** unaffected by: xPtpn12(del(297-493)) [substitution]
    *** unaffected by: xPtpn12(P337A) [substitution]
    *** source: 11337490-Fig-8a
  *** xFak2[Ab]IP Yphos[pYAb] is detectable
    *** cells: COS7<xFak2> in BMS
    *** inhibited by: xFak2(Y402F) [substitution]
    *** inhibited by: xFak2(K457R) [substitution]
    *** source: 9242628-Fig-3a
  *** xFak2[Ab]IP Yphos[pYAb] is detectable
    *** cells: COS7<xFak2> in BMS
    *** inhibited by: xFak2(Y402F) [substitution]
    *** inhibited by: xFak2(K457R) [substitution]
    *** source: 9242628-Fig-4a
  *** xFak2[Ab]IP Yphos[pYAb] is detectable
    *** cells: HEK293<xFak2> in BMS
    *** inhibited by: xPtpn12 [addition]
    *** source: 11337490-Fig-2a
  *** xFak2[Ab]IP Yphos[pYAb] is detectable
    *** cells: HEK293<xFak2> in BMS
    *** inhibited by: xPtpn12 [addition]
    *** source: 11337490-Fig-3b
  *** xFak2[Ab]IP Yphos[pYAb] is detectable
    *** cells: HEK293<xFak2> in BMS "treated with pervanadate"
    *** partially inhibited by: xFak2(Y402F) [substitution]
    *** inhibited by: xFak2(Y579F/Y580F) [substitution]
    *** source: 11337490-Fig-5a
  *** xFak2[tAb] copptby[WB] Src[Ab] is detectable
    *** cells: COS7<xFak2> in BMS
    *** inhibited by: xFak2(Y402F) [substitution]
    *** inhibited by: xFak2(K457R) [substitution]
    *** source: 9242628-Fig-4b
  *** xFak2[tAb]IP Yphos[pYAb] is increased itpo Hras(G12V)"CA"
    *** cells: HEK293<xFak2> in BMS
    *** partially inhibited by: PP1 [addition] no-bkg-control
    *** partially inhibited by: BaptaAM [addition] no-bkg-control
    *** partially inhibited by: LY294002 [addition] no-bkg-control
    *** inhibited by: PP1 + BaptaAM [addition] no-bkg-control
    *** partially inhibited by: PP1 + LY294002 [addition] no-bkg-control
    *** partially inhibited by: BaptaAM + LY294002 [addition] no-bkg-control
    *** inhibited by: PP1 + BaptaAM + LY294002 [addition] no-bkg-control
    *** source: 16199135-Fig-4a
  *** xFan(3-917)[tAb] copptby[WB] TnfR1[Ab] is detectable
    *** cells: COS1 in BMS
    *** source: 8808629-Fig-4
  *** Fan[Ab] copptby[WB] TnfR1[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 12361233-Fig-5c
  *** xFan[tAb] colocwith[IHC] xRack1[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 12361233-Fig-6
  *** xFan[tAb] colocwith[IHC] xTnfR1(1-317)"death-domain-mut"[tAb] is detectable
    *** cells: COS1 in BMS
    *** unaffected by: xRack1 [addition]
    *** source: 12361233-Fig-6
  *** xFan[tAb] copptby[WB] TnfR1[Ab] is detectable
    *** cells: U937 in BMS
    *** enhanced by: Monodansylcadaverine [addition]
    *** source: 10187805-Fig-6a
  *** xFan[tAb] copptby[WB] xRack1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12361233-Fig-5b
*** FasR--
  *** FasR-gene mRNA[Northern] is increased itpo (xIL12a + xIL12b)
    *** cells: TC71 in BMS
    *** source: 16380506-Fig-1
  *** FasR-gene mRNA[RTPCR] is detectable
    *** cells: mEFs in BMS
    *** reqs: Egr1 [KO]
    *** source: 15958557-Fig-1
  *** FasR-gene mRNA[RTPCR] is detectable
    *** cells: mSpBCs in BMS "treated with anti-Cd40 (24 hr)"
    *** partially inhibited by: kMekk1(1-1188)"del-kinase-domain" [addition]
    *** source: 17143273-Fig-6c
  *** FasR-gene mRNA[RTPCR] is detectable-but unchanged itpo xStat1
    *** cells: U3A<Stat1~null> in BMLS
    *** unaffected by: xStat1(L407A/L409A) [substitution]
    *** source: 11823427-Fig-5c
  *** FasR-gene mRNA[RTPCR] is increased itpo (xIL12a + xIL12b)
    *** cells: LM7 in BMS
    *** source: 16380506-Fig-2a
  *** FasR-gene mRNA[RTPCR] is increased itpo (xIL12a + xIL12b)
    *** cells: TC71 in BMS
    *** source: 16380506-Fig-2a
  *** FasR-gene promo-reporter[Luc] is increased itpo (xIL12a + xIL12b)
    *** cells: LM7 in BMS
    *** source: 16380506-Fig-3a
  *** FasR-gene promo-reporter[Luc] is increased itpo (xIL12a + xIL12b)
    *** cells: LM7 in BMS
    *** source: 16380506-Fig-5a
  *** FasR-gene promo-reporter[Luc] is increased itpo (xIL12a + xIL12b)
    *** cells: TC71 in BMS
    *** source: 16380506-Fig-3b
  *** FasR[Ab] prot-exp[WB] is unchanged itao St6gal1 [RNAi]
    *** cells: HD3<xHras(G12V)> in BMS
    *** source: 21550977-Fig-1b
  *** FasR[Ab] snaggedby[WB] MAA[agarose] is unchanged itao St6gal1 [RNAi]
    *** cells: HD3<xHras(G12V)> in BMS
    *** source: 21550977-Fig-4a
  *** FasR[Ab] snaggedby[WB] SNA1[agarose] is decreased itao St6gal1 [RNAi]
    *** cells: HD3<xHras(G12V)> in BMS
    *** source: 21550977-Fig-4a
  *** FasR[Ab] snaggedby[WB] SNA1[agarose] is increased itpo xSt6gal1
    *** cells: SW48 in BMS
    *** source: 21550977-Fig-4b
  *** FasR[Ab] surface-exp[FACS] is increased itpo (xIL12a + xIL12b)
    *** cells: TC71 in BMS
    *** source: 16380506-Fig-2b
  *** FasR[Ab] surface-exp[FACS] is unchanged itao St6gal1 [RNAi]
    *** cells: HD3<xHras(G12V)> in BMS
    *** source: 21550977-Fig-4d
  *** FasR[Ab] surface-exp[FACS] is unchanged itpo xSt6gal1
    *** cells: SW48 in BMS
    *** source: 21550977-Fig-4d
*** Fbxw2--
  *** xFbxw2[tAb] copptby[WB] Ctnnb1[Ab] is undetectable
    *** cells: HEK293T<xFbxw2><xAxin1> in BMS
    *** source: 10228155-Fig-1b
  *** xFbxw2[tAb] copptby[WB] xAxin1[tAb] is undetectable
    *** cells: HEK293T<xFbxw2><xAxin1> in BMS
    *** source: 10228155-Fig-1b
  *** xFbxw2[tAb] copptby[WB] xMyc[tAb] is undetectable
    *** cells: HEK293T in BMS "treated with MG132 for 6 hr"
    *** source: 15103331-Fig-1b
*** Fbxw4--
  *** xFbxw4[tAb] copptby[WB] xMyc[tAb] is undetectable
    *** cells: HEK293T in BMS "treated with MG132 for 6 hr"
    *** source: 15103331-Fig-1b
  *** xFbxw4[tAb] snaggedby[WB] rMyc(51-66)[agarose] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15103331-Fig-3a
*** Fbxw7--
  *** xFbxw7[tAb] copptby[WB] Myc[Ab] is detectable
    *** cells: HEK293T in BMS "treated with MG132 for 6 hr"
    *** inhibited by: GSK3inhibitorII [cotreatment]
    *** source: 15103331-Fig-3e
  *** xFbxw7[tAb] copptby[WB] Myc[Ab] is detectable
    *** cells: HEK293T in BMS "treated with MG132 for 6 hr"
    *** source: 15103331-Fig-1c
  *** xFbxw7[tAb] copptby[WB] xMyc[tAb] is detectable
    *** cells: HEK293T in BMS "treated with MG132 for 6 hr"
    *** inhibited by: xMyc(T58A) [substitution]
    *** inhibited by: xMyc(S62A) [substitution]
    *** inhibited by: xMyc(T58A/S62A) [substitution]
    *** source: 15103331-Fig-3b
  *** xFbxw7[tAb] copptby[WB] xMyc[tAb] is detectable
    *** cells: HEK293T in BMS "treated with MG132 for 6 hr"
    *** source: 15103331-Fig-1b
  *** xFbxw7[tAb] snaggedby[WB] rMyc(51-66){phos(T58/T62)}[agarose] is detectable
    *** cells: HEK293T in BMS
    *** comment: reqs rMyc(51-66) phos on T58 and S62 [substitution]
    *** source: 15103331-Fig-3a
*** FceR2--
  *** FceR2[Ab] surface-exp[FACS] is decreased itpo Bcl6
    *** cells: WIL2NS in BMS
    *** source: 9110977-Fig-5c
  *** FceR2[Ab] surface-exp[FACS] is increased itpo xStat6
    *** cells: mBC<Cd45~pos> in BMS "Lps-blasts"
    *** enhanced by: xParp14 [addition]
    *** source: 16537510-Fig-3b
  *** FceR2[Ab] surface-exp[FACS] is increased itpo xStat6
    *** cells: mBC<Cd45~pos> in BMS "Lps-blasts"
    *** enhanced by: xParp14(1216-1817) [addition]
    *** enhanced by: xParp14(mnr)"macroH2A-domains" [addition]
    *** enhanced by: xParp14(mnr)"macroH2A-domains/Cterm" [addition]
    *** source: 16537510-Fig-5b
  *** FceR2[Ab] surface-exp[FACS] is increased itpo xStat6
    *** cells: mBC<Cd45~pos> in BMS "Lps-blasts"
    *** unaffected by: xTbet [addition]
    *** source: 16537510-Fig-5b
  *** FceR2[Ab] surface-exp[FACS] is unchanged itpo (xParp14 + xThy1)
    *** cells: mBC<Cd45~pos> in BMS "Lps-blasts"
    *** source: 16537510-Fig-3b
  *** Fer[Ab]IP Yphos[pYAb] is detectable
    *** cells: NIH3T3 in BMLS
    *** unaffected by: Egf (5 min) [stim]
    *** source: 7623846-Fig-3a
  *** xFer[tAb] Yphos[pYAb-ppt] is detectable
    *** cells: CHO in BMS
    *** source: 10878010-Fig-5c
  *** xFer[tAb]IP IVKA(Ctnnb1)[pYAb] is increased itpo xKras(G12V)"CA"
    *** cells: IEC18 in BMS
    *** source: 12640114-Fig-5b
  *** xFer[tAb]IP Yphos[pYAb] is increased itpo xKras(G12V)"CA"
    *** cells: IEC18 in BMS
    *** source: 12640114-Fig-5a
  *** xFes[Ab]IP Yphos[pYAb] is detectable
    *** cells: COS7 in BMLS
    *** unaffected by: xIL4R [addition]
    *** source: 8916957-Fig-4a
  *** xFgfR1[Ab] copptby[WB] xFrs2[Ab] is detectable
    *** cells: HEK293<xFrs2><xFgfR1> in BMS
    *** unaffected by: xFgfR1(mnr)"KD" [substitution]
    *** source: 10629055-Fig-1c
  *** FgfR1[Ab]IP ubiq[tUbAb] is detectable
    *** cells: HEK293T<xUbiq> in BMS
    *** unaffected by: xCbl [addition]
    *** source: 12815057-Fig-5a
  *** FgfR1[Ab]IP ubiq[tUbAb] is detectable
    *** cells: HEK293T<xUbiq> in BMS
    *** unaffected by: xSpry2 [addition]
    *** partially inhibited by: xSpry2(Y55F) [addition]
    *** source: 12815057-Fig-5a
  *** xFgfR1[Ab]IP Yphos[pYAb] is detectable
    *** cells: HEK293<xFrs2> in BMS
    *** inhibited by: xFgfR1(mnr)"KD" [substitution]
    *** source: 10629055-Fig-1c
  *** xFgfR1[Ab]IP Yphos[pYAb] is detectable
    *** cells: HEK293<xFrs2> in BMS
    *** unaffected by: xFrs2 [addition]
    *** unaffected by: xFrs2(1-158/G2A) [addition]
    *** unaffected by: xFrs2(1-158) [addition]
    *** source: 10629055-Fig-2a
  *** xFgr[Ab] copptby[WB] xStat3[GST] is detectable
    *** cells: SF9 in BMS
    *** source: 12244095-Fig-3
  *** FHRE-reporter[Luc] is increased itpo xFoxo3
    *** cells: CCL39 in BMLS
    *** inhibited by: xAkt1(mnr)"CA" [addition]
    *** source: 11154281-Fig-6a
  *** FHRE-reporter[Luc] is increased itpo xFoxo3
    *** cells: CCL39 in BMLS
    *** inhibited by: xSgk1 [addition]
    *** inhibited by: xSgk1(S422D)"CA" [addition]
    *** source: 11154281-Fig-6a
  *** FHRE-reporter[Luc] is increased itpo xFoxo3
    *** cells: CCL39 in BMLS
    *** inhibited by: xSgk1(S422D)"CA" [addition]
    *** source: 11154281-Fig-6a
  *** FHRE-reporter[Luc] is increased itpo xFoxo3
    *** cells: CCL39 in BMLS
    *** partially inhibited by: xPKA(mnr)"CA" [addition]
    *** source: 11154281-Fig-6a
  *** FHRE-reporter[Luc] is increased itpo xFoxo3
    *** cells: CCL39 in BMLS
    *** unaffected by: xPkci(mnr)"CA" [addition]
    *** source: 11154281-Fig-6a
  *** FHRE-reporter[Luc] is increased itpo xFoxo3
    *** cells: CCL39 in BMLS
    *** unaffected by: xPkcz(mnr)"CA" [addition]
    *** source: 11154281-Fig-6a
  *** FHRE-reporter[Luc] is increased itpo xFoxo3
    *** cells: CCL39 in BMLS
    *** unaffected by: xRsk2(mnr)"CA" [addition]
    *** source: 11154281-Fig-6a
  *** FHRE-reporter[Luc] is increased itpo xFoxo3
    *** cells: CCL39 in BMS "treated with Igf1 for 24 hr"
    *** enhanced by: xFoxo3(T32A) [substitution]
    *** enhanced by: xFoxo3(T253A) [substitution]
    *** enhanced by: xFoxo3(S315A) [substitution]
    *** enhanced by: xFoxo3(T32A/T253A) [substitution]
    *** enhanced by: xFoxo3(T32A/S315A) [substitution]
    *** enhanced by: xFoxo3(T253A/S315A) [substitution]
    *** enhanced by: xFoxo3(T32A/T253A/S315A) [substitution]
    *** source: 11154281-Fig-6a
  *** xFlip[tAb] copptby[WB] xNod1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 10329646(D)
  *** rFlna[32P] phos[32P-ATP] is unchanged by xAkt1[tAb]IP
    *** cells: none
    *** IPfrom: HEK293E in BMLS "treated with Insulin for 20 min"
    *** unaffected by: rFlna(S2152A) [substitution]
    *** source: 15024089-Fig-1c
  *** xFlna[tAb]IP phos[32Pi] is detectable
    *** cells: HEK293E<xFlna> in BMLS
    *** inhibited by: xFlna(S2152A) [substitution]
    *** source: 15024089-Fig-3b
  *** Fmr1[Ab] colocwith[IHC] Stau1[Ab] is detectable
    *** cells: SHSY5Y in BMS "differentiated with retinoic acid for 7 days"
    *** source: 15121898(D)
  *** Fmr1[Ab] copptby[WB] xStau1[tAb] is detectable
    *** cells: HEK293T in BMS "infected with vaccinia vTf7-3 virus"
    *** source: 15121898(D)
  *** Fn1-gene mRNA[Northern] is increased itpo xPin1
    *** cells: MCF7 in BMS
    *** source: 11533658-Fig-1b
  *** Fn1-gene promo-reporter[Luc] is decreased itpo xErbin
    *** cells: AKR2B in BMLS "treated with Tgfb1 for 45 min"
    *** reqs: Merlin [RNAi]
    *** source: 19289088-Fig-4d
*** Fos--
  *** Fos-gene mRNA[Northern] is increased itpo xMekk1
    *** cells: HELA in BMLS
    *** source: 8846788-Fig-2
  *** Fos-gene mRNA[RTPCR] is decreased itao Pias2a [RNAi]
    *** cells: HELA in BMLS
    *** source: 15920481-Fig-1e
  *** Fos-gene mRNA[RTPCR] is detectable
    *** cells: HELA in BMS
    *** does not req: Arrb2 [RNAi]
    *** unaffected by: xArrb2 [addition]
    *** source: 16325578-Fig-2a
  *** Fos-gene mRNA[RTPCR] is detectable
    *** cells: HELA in BMS
    *** partially reqs: Arrb1 [RNAi]
    *** unaffected by: xArrb1 [addition]
    *** unaffected by: xArrb1(Q394L) [addition]
    *** source: 16325578-Fig-2a
  *** Fos-gene mRNA[RTPCR] is detectable
    *** cells: HELA in BMS
    *** partially reqs: Arrb1 [RNAi]
    *** unaffected by: xArrb1 [addition]
    *** unaffected by: xArrb1(Q394L) [addition]
    *** source: 16325578-Fig-6a
  *** Fos-gene mRNA[RTPCR] is detectable
    *** cells: mSpBCs in BMS "treated with anti-Cd40 (24 hr)"
    *** unaffected by: kMekk1(1-1188)"del-kinase-domain" [addition]
    *** source: 17143273-Fig-6c
  *** Fos-gene mRNA[RTPCR] is unchanged itpo xArrb1
    *** cells: mEFs<Arrb1~null><Arrb2~null> in BMS
    *** source: 16325578-Fig-2b
  *** Fos-gene mRNA[RTPCR] is unchanged itpo xArrb2
    *** cells: mEFs<Arrb1~null><Arrb2~null> in BMS
    *** source: 16325578-Fig-2b
  *** Fos-gene mRNA[RTPCR] is unchanged itpo xEp300
    *** cells: HELA in BMS
    *** inhibited by: xEp300(mnr)"DN" [substitution]
    *** source: 16325578-Fig-6a
  *** Fos-gene mRNA[RTPCR] is unchanged itpo xEp300
    *** cells: mEFs<Arrb1~null><Arrb2~null> in BMS
    *** inhibited by: xEp300(mnr)"DN" [substitution]
    *** source: 16325578-Fig-6b
  *** Fos-gene promo-reporter[CAT] is increased itpo xMek1(mnr)"CA"
    *** cells: NIH3T3 in BMS
    *** enhanced by: xElk1 [addition]
    *** source: 10022839-Fig-7b
  *** Fos-gene promo-reporter[CAT] is increased itpo xMek1(mnr)"CA"
    *** cells: NIH3T3 in BMS
    *** inhibited by: xId2 [addition]
    *** source: 10022839-Fig-7a
  *** Fos-gene promo-reporter[CAT] is increased itpo xMek1(mnr)"CA"
    *** cells: NIH3T3 in BMS
    *** inhibited by: xId2 [addition]
    *** source: 10022839-Fig-7b
  *** Fos-gene promo-reporter[Luc] is increased itpo xElk1
    *** cells: HEK293 in BMS
    *** enhanced by: xElk1(K230R/K249R) [substitution]
    *** source: 12887893-Fig-1e
  *** rFos(209-380){phos}[Ab] boundby[WB] rPin1[GST] is detectable
    *** cells: none
    *** comment: rFos was phosed by activated Erk2
    *** inhibited by: rFos(T232A/T325A/T331A/S374A) [substitution]
    *** partially inhibited by: rFos(T232A) [substitution]
    *** inhibited by: rFos(T325A) [substitution]
    *** inhibited by: rFos(T331A) [substitution]
    *** inhibited by: rFos(S374A) [substitution]
    *** source: 16123044-Fig-3a
  *** xFos(210-308)[Gal4-DBD] Gal4-reporter[CAT] is increased itpo xHras(G12V)
    *** cells: 1BR in BMS
    *** inhibited by: xHras(G12V/C186S) [substitution]
    *** source: 7816602-Fig-2
  *** xFos(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xPin1
    *** cells: NIH3T3 in BMLS
    *** inhibited by: rFos((209-380)/T232A/T325A/T331A/S374A) [substitution]
    *** source: 16123044-Fig-4b
  *** xFos(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xPin1
    *** cells: NIH3T3 in BMLS
    *** source: 16123044-Fig-4a
  *** rFos[32P] phos[32P-ATP] is increased by Rsks{act}[Ab]IP
    *** cells: none
    *** IPfrom: NIH3T3 in BMLS "treated with serum (5 min)"
    *** comment: phos site was determined to be S362 by tryptic peptide mapping
    *** source: 8248197-Fig-1a
  *** rFos[32P] phos[32P-ATP] is unchanged by S6ks{act}[Ab]IP
    *** cells: none
    *** IPfrom: NIH3T3 in BMLS "treated with serum (5 min)"
    *** source: 8248197-Fig-1a
  *** rFos[32P] phos[32P-ATP] is unchanged by xErk5[tAb]IP
    *** cells: none
    *** comment: xErk5[tAb]IP is from HEK293-xMek5(mnr)"CA"
    *** unaffected by: rFos(S362E/S374E) [substitution]
    *** unaffected by: rFos(S362A/S374A) [substitution]
    *** source: 12134156-Fig-S2c
  *** rFos[35S] boundby[WB] rEts2[GST] is detectable
    *** cells: none
    *** enhanced by: xJun [addition]
    *** source: 9334186-Fig-1a
  *** rFos[35S] boundby[WB] rSmad3[GST] is detectable
    *** cells: none
    *** inhibited by: rSmad3(1-144)"N-term" [substitution]
    *** inhibited by: rSmad3(1-210)"LN-term" [substitution]
    *** enhanced by: rSmad3(210-425)"C-term" [substitution]
    *** enhanced by: rSmad3(144-425)"LC-term" [substitution]
    *** source: 9732876-Fig-2h
  *** rFos[35S] boundby[WB] rSmad3[GST] is detectable
    *** cells: none
    *** source: 9732876-Fig-2g
  *** rFos[35S] boundby[WB] rSmad4[GST] is undetectable
    *** cells: none
    *** source: 9732876-Fig-2h
  *** Fos[Ab] boundto(A2m-gene)[ChIP] is detectable
    *** cells: H35 in BMS
    *** unaffected by: Dexamethasone [addition]
    *** unaffected by: IL6 (30 min) [stim]
    *** source: 14522952-Fig-4b
  *** Fos[Ab] oligo-binding[EMSA] is increased itpo xPld2
    *** cells: HEK293T<xEgfR> in BMLS
    *** enhanced by: xArf4(Q71L)"CA" [addition]
    *** source: 12446727-Fig-6b
  *** xFos[Ab] snaggedby[WB] oligo[biotin] is detectable
    *** cells: COS1<xTgfbR1(mnr)"CA"><xTgfbR2> in BMS
    *** oligo: AP1 5-CGCTTGATGAGTCAGCCGGAA-3
    *** source: 9732876-Fig-3d
  *** xFos[Gal4-DBD] Gal4-reporter[CAT] is detectable
    *** cells: COS1<xRaRa> in BMS "charcoal/dextran treated serum"
    *** inhibited by: ATRA (24 hr) [stim]
    *** source: 9671405-Fig-3
  *** xFos[Gal4-DBD] Gal4-reporter[CAT] is increased itpo xPml
    *** cells: COS1 in BMS
    *** comment: experiment shows effects of xPml domains but constructs are unclear
    *** source: 9671405-Fig-4b
  *** xFos[Gal4-DBD] Gal4-reporter[CAT] is increased itpo xPml
    *** cells: COS1 in BMS
    *** inhibited by: xFos(1-81) [substitution]
    *** bkg inhibited by: xFos(1-142) [substitution]
    *** unaffected by: xFos(143-380) [substitution]
    *** partially inhibited by: xFos(210-380) [substitution]
    *** partially inhibited by: xFos(250-380) [substitution]
    *** source: 9671405-Fig-4a
  *** xFos[Gal4-DBD] Gal4-reporter[CAT] is increased itpo xPml
    *** cells: COS1 in BMS "charcoal/dextran treated serum"
    *** unaffected by: ATRA (24 hr) [stim]
    *** source: 9671405-Fig-2
  *** xFos[Gal4-DBD] Gal4-reporter[CAT] is unchanged itpo xRaRa
    *** cells: COS1 in BMS "charcoal/dextran treated serum"
    *** inhibited by: ATRA (24 hr) [stim]
    *** source: 9671405-Fig-2
  *** xFos[phosAb] phos(T325)[phosAb] is detectable
    *** cells: NIH3T3 in BMS
    *** inhibited by: rFos(T325A) [substitution]
    *** inhibited by: rFos(S362D/S374D/T325A) [substitution]
    *** source: 12134156-Fig-5b
  *** xFos[phosAb] phos(T325)[phosAb] is detectable
    *** cells: NIH3T3 in BMS
    *** inhibited by: xFos(S362A/S374A) [substitution]
    *** source: 12134156-Fig-5c
  *** xFos[phosAb] phos(T325)[phosAb] is increased itpo xBraf(mnr)"CA"
    *** cells: NIH3T3 in BMS
    *** source: 12134156-Fig-5c
  *** xFos[tAb] copptby[WB] xPin1[tAb] is detectable
    *** cells: HEK293T in BMLS
    *** unaffected by: Egf (30 min) [stim]
    *** inhibited by: xFos(T232A/T325A/T331A/S374A) [substitution]
    *** source: 16123044-Fig-2b
  *** xFos[tAb] oligo-binding[EMSA] is detectable
    *** cells: COS1<xTgfbR1(mnr)"CA"><xTgfbR2><xSmad3><xSmad4><xJun> in BMS
    *** oligo: AP1 5-CGCTTGATGAGTCAGCCGGAA-3
    *** source: 9732876-Fig-3f
  *** xFos[tAb] snaggedby[WB] rPin1[GST] is detectable
    *** cells: NIH3T3 in BMLS
    *** unaffected by: Pdgf (30 min) [stim]
    *** unaffected by: Serum (30 min) [stim]
    *** inhibited by: xFos(T232A/T325A/T331A/S374A) [substitution]
    *** source: 16123044-Fig-2a
  *** xFos[tAb] snaggedby[WB] rPin1[GST] is increased itpo (xErk2 + xMek1(mnr)"CA")
    *** cells: NotReported in BMS
    *** inhibited by: xFos(T232A/T325A/T331A/S374A) [substitution]
    *** source: 16123044-Fig-3a
  *** xFos[XFP] locatedin(nucleus)[IHC] is detectable
    *** cells: COS1 in BMS
    *** source: 16511568-Fig-1a
  *** xFos[XFP] locatedin(nucleus)[IHC] is detectable
    *** cells: COS1<xJun> in BMS
    *** comment: xFos is dimerized with xJun [BiFC]
    *** source: 16511568-Fig-1a
*** Foxh1--
  *** xFoxh1[tAb] snaggedby[WB] rSmad2(185-467)"LMH2"[GST] is detectable
    *** cells: COS1 in BMS
    *** inhibited by: rSmad2((185-467)/L382R/K383A) [substitution]
    *** inhibited by: rSmad2((185-467)/P445H) [substitution]
    *** unaffected by: rSmad2((185-467)/W448A) [substitution]
    *** unaffected by: rSmad2((185-467)/V398R) [substitution]
    *** unaffected by: rSmad2((185-467)/C380R/L382R) [substitution]
    *** source: 12191473-Fig-2e
*** Foxo1--
  *** rFoxo1[32P] phos[32P-ATP] is unchanged by pAmpk
    *** cells: none
    *** source: 17711846-Fig-1c
  *** Foxo1[Ab] copptby[WB] Erk2[Ab] is undetectable
    *** cells: HEPG2 in BMLS "pretreated with LY294002, followed by Serum for 10 min"
    *** source: 12456685-Fig-6b
  *** Foxo1[Ab] copptby[WB] Smad23s[Ab] is undetectable
    *** cells: HEPG2 in BMLS "pretreated with LY294002, followed by Tgfb1 for 10 min"
    *** source: 12456685-Fig-6b
  *** Foxo1[Ab] copptby[WB] Stat3[Ab] is detectable
    *** cells: HEPG2 in BMLS "pretreated with LY294002, followed by IL6 for 10 min"
    *** source: 12456685-Fig-6a
  *** Foxo1[Ab] copptby[WB] Stat3[Ab] is detectable
    *** cells: HEPG2 in BMLS "pretreated with LY294002, followed by IL6 for 10 min"
    *** source: 12456685-Fig-6b
  *** Foxo1[Ab] copptby[WB] Stat5s[Ab] is undetectable
    *** cells: HEPG2 in BMLS "pretreated with LY294002, followed by Ifng for 10 min"
    *** source: 12456685-Fig-6b
  *** Foxo1[Ab] infraction(nuclear)[WB] is increased itao Freud1 [RNAi]
    *** cells: HEK293T in BMS
    *** source: 18662999-Fig-3f
  *** Foxo1[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: HELA in BMLS
    *** comment: Foxo1 relocates to nucleus itpo xIkke
    *** source: 21464307-Fig-S1
  *** Foxo1[phosAb] phos(S256)[phosAb] is increased itpo xAkt1
    *** cells: PC3 in BMS
    *** partially inhibited by: xAkt1(S473D) [substitution]
    *** source: 16603397-Fig-4b
  *** xFoxo1[phosAb] phos(sitenr)[phosAb] is decreased itpo xPtk6
    *** cells: COS1<xFoxo1> in BMS
    *** source: 15539407-Fig-6a
  *** xFoxo1[phosAb] phos(sitenr)[phosAb] is detectable
    *** cells: COS1<xFoxo1> in BMS
    *** inhibited by: xFoxo1(mnr)"T24/S256/S318-mutant" [substitution]
    *** source: 15539407-Fig-6a
  *** xFoxo1[tAb] copptby[WB] xAkt1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 11410590-Fig-4b
  *** xFoxo1[tAb] copptby[WB] xSgk1[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 11410590-Fig-4b
*** Foxo3--
  *** Foxo3[Ab] infraction(nuclear)[WB] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: Freud1 [RNAi]
    *** source: 18662999-Fig-3f
  *** xFoxo3[Ab] oligo-binding[EMSA] is detectable
    *** cells: HEK293T<xFoxo3> in BMS
    *** unaffected by: xFoxo3(T32A/S253A/S315A) [substitution]
    *** source: 10102273-Fig-5
  *** xFoxo3[phosAb] phos(S253)[phosAb] is detectable
    *** cells: HEK293T<xFoxo3> in BMS
    *** unaffected by: xFoxo3(T32A) [substitution]
    *** inhibited by: xFoxo3(S253A) [substitution]
    *** unaffected by: xFoxo3(S315A) [substitution]
    *** inhibited by: xFoxo3(T32A/S253A/S315A) [substitution]
    *** inhibited by: xFoxo3(T32A/S253A) [substitution]
    *** inhibited by: xFoxo3(S253A/S315A) [substitution]
    *** unaffected by: xFoxo3(T32A/S315A) [substitution]
    *** source: 10102273-Fig-2a
  *** xFoxo3[phosAb] phos(S253)[phosAb] is unchanged itpo xPKA(mnr)"CA"
    *** cells: CCL39<xFoxo3> in BMS
    *** source: 11154281-Fig-3
  *** xFoxo3[phosAb] phos(S253)[phosAb] is unchanged itpo xPkci(mnr)"CA"
    *** cells: CCL39<xFoxo3> in BMS
    *** source: 11154281-Fig-3
  *** xFoxo3[phosAb] phos(S253)[phosAb] is unchanged itpo xPkcz(mnr)"CA"
    *** cells: CCL39<xFoxo3> in BMS
    *** source: 11154281-Fig-3
  *** xFoxo3[phosAb] phos(S253)[phosAb] is unchanged itpo xRsk2(mnr)"CA"
    *** cells: CCL39<xFoxo3> in BMS
    *** source: 11154281-Fig-3
  *** xFoxo3[phosAb] phos(T32)[phosAb] is detectable
    *** cells: HEK293T<xFoxo3> in BMS
    *** inhibited by: xFoxo3(T32A) [substitution]
    *** unaffected by: xFoxo3(S253A) [substitution]
    *** unaffected by: xFoxo3(S315A) [substitution]
    *** inhibited by: xFoxo3(T32A/S253A/S315A) [substitution]
    *** inhibited by: xFoxo3(T32A/S253A) [substitution]
    *** unaffected by: xFoxo3(S253A/S315A) [substitution]
    *** inhibited by: xFoxo3(T32A/S315A) [substitution]
    *** source: 10102273-Fig-2a
  *** xFoxo3[phosAb] phos(T32)[phosAb] is increased itpo xPKA(mnr)"CA"
    *** cells: CCL39<xFoxo3> in BMS
    *** source: 11154281-Fig-3
  *** xFoxo3[phosAb] phos(T32)[phosAb] is unchanged itpo xPkci(mnr)"CA"
    *** cells: CCL39<xFoxo3> in BMS
    *** source: 11154281-Fig-3
  *** xFoxo3[phosAb] phos(T32)[phosAb] is unchanged itpo xPkcz(mnr)"CA"
    *** cells: CCL39<xFoxo3> in BMS
    *** source: 11154281-Fig-3
  *** xFoxo3[phosAb] phos(T32)[phosAb] is unchanged itpo xRsk2(mnr)"CA"
    *** cells: CCL39<xFoxo3> in BMS
    *** source: 11154281-Fig-3
  *** Foxo3[phosAb] phos(T32/S253)[phosAb] is detectable
    *** cells: PC12 in BMS
    *** inhibited by: Hras(A17N)"DN" [addition]
    *** source: 11953455-Fig-4
  *** Foxo3[phosAb] phos(T32/S253)[phosAb] is detectable
    *** cells: rECNs in BMS
    *** inhibited by: Wortmannin [pretreatment]
    *** inhibited by: PD98059 [pretreatment]
    *** unaffected by: Rapamycin [pretreatment]
    *** source: 11953455-Fig-10c
  *** Foxo3[phosAb] phos(T32/S253)[phosAb] is detectable
    *** cells: rECNs in BMS
    *** inhibited by: Wortmannin [pretreatment]
    *** inhibited by: PD98059 [pretreatment]
    *** unaffected by: Rapamycin [pretreatment]
    *** source: 11953455-Fig-10d
  *** rFoxo3[RE] oligo-binding[EMSA] is detectable
    *** cells: none
    *** unaffected by: rFoxo3(T179A) [substitution]
    *** unaffected by: rFoxo3(T179A/S399A/S413A/S555A/S588A/S626A) [substitution]
    *** source: 17711846-Fig-5c
  *** xFoxo3[tAb] copptby[WB] xYwhaz[tAb] is detectable
    *** cells: HEK293T<xFoxo3><xYwhaz> in BMS
    *** unaffected by: xFoxo3(mnr)"NES12m" [substitution]
    *** inhibited by: xFoxo3(T32A/S253A/S315A) [substitution]
    *** source: 11864996-Fig-5c
  *** xFoxo3[tAb] locatedin(cytoplasm)[IHC] is detectable
    *** cells: CCL39<xFoxo3> in BMS
    *** inhibited by: LMB [addition]
    *** source: 11864996-Fig-5c
  *** xFoxo3[tAb] locatedin(cytoplasm)[IHC] is detectable
    *** cells: CCL39<xFoxo3> in BMS
    *** inhibited by: xFoxo3(mnr)"NES12m" [substitution]
    *** inhibited by: xFoxo3(T32A/S253A/S315A) [substitution]
    *** source: 11864996-Fig-5c
  *** xFoxo3[tAb] locatedin(cytoplasm)[IHC] is detectable
    *** cells: CCL39<xFoxo3> in BMS
    *** unaffected by: xFoxo3(R248A/R249A/R250A) [substitution]
    *** unaffected by: xFoxo3(K269A/K270A/K271A) [substitution]
    *** inhibited by: xFoxo3(mnr)"NES12m" [substitution]
    *** inhibited by: xFoxo3(T32A/S253A/S315A) [substitution]
    *** source: 11864996-Fig-7
  *** xFoxo3[tAb] locatedin(cytoplasm)[IHC] is detectable
    *** cells: CCL39<xFoxo3> in BMS "treated with Igf1 for 12 hr"
    *** unaffected by: xFoxo3(R248A/R249A/R250A) [substitution]
    *** unaffected by: xFoxo3(K269A/K270A/K271A) [substitution]
    *** partially inhibited by: xFoxo3(mnr)"NES12m" [substitution]
    *** inhibited by: xFoxo3(T32A/S253A/S315A) [substitution]
    *** source: 11864996-Fig-7
  *** xFoxo3[tAb] locatedin(nucleus)[IHC] is detectable
    *** cells: CCL39<xFoxo3> in BMS "treated with LY294002 for 1 hr"
    *** inhibited by: xFoxo3(R248A/R249A/R250A) [substitution]
    *** partially inhibited by: xFoxo3(K269A/K270A/K271A) [substitution]
    *** enhanced by: xFoxo3(mnr)"NES12m" [substitution]
    *** enhanced by: xFoxo3(T32A/S253A/S315A) [substitution]
    *** source: 11864996-Fig-7
*** Foxo4--
*** Foxo4--
  *** Foxo4[phosAb] phos(S193)[phosAb] is detectable
    *** cells: M059J in BMLS
    *** does not req: Raptor [RNAi]
    *** source: 15718470-Fig-S3
  *** Foxo4[phosAb] phos(S193)[phosAb] is detectable
    *** cells: M059J in BMLS
    *** reqs: Mtor [RNAi]
    *** source: 15718470-Fig-S3
  *** Foxo4[phosAb] phos(S193)[phosAb] is detectable
    *** cells: M059J in BMLS
    *** reqs: Rictor [RNAi]
    *** source: 15718470-Fig-S3
  *** Foxo4[phosAb] phos(S256)[phosAb] is detectable-but unchanged itpo xAkt1
    *** cells: PC3 in BMS
    *** unaffected by: xAkt1(S473D) [substitution]
    *** source: 16603397-Fig-4b
  *** xFoxo4[tAb]IP phos(T447/T451)[2D-PPMap] is increased itpo xHras(G12V)"CA"
    *** cells: NIH3T3<xInsR> in BMS
    *** source: 11689711(D)
  *** xFoxo4[tAb]IP phos(T447/T451)[2D-PPMap] is increased itpo xRgl2(mnr)"CAAX"
    *** cells: NIH3T3<xInsR> in BMS
    *** source: 11689711(D)
*** Foxo6--
  *** rFoxo6[32P] phos[32P-ATP] is unchanged by pAmpk
    *** cells: none
    *** source: 17711846-Fig-1c
  *** Foxo13s[phosAb] phos(CTWPL)[phosAb] is detectable
    *** cells: HELA<xTbk1> in BMS
    *** inhibited by: xTbk1(mnr)"KD" [substitution]
    *** source: 21464307-Fig-S5a
  *** Foxo13s[phosAb] phos(CTWPL)[phosAb] is detectable
    *** cells: HELA<xTbk1> in BMS
    *** partially reqs: Mtor [RNAi]
    *** partially reqs: Rictor [RNAi]
    *** comment: effect of Mtor, Rictor may be due to decrease in Foxo1 prot-exp
    *** source: 21464307-Fig-S5a
  *** Foxo13s[phosAb] phos(CTWPL)[phosAb] is increased itpo xIkke
    *** cells: HELA in BMS
    *** inhibited by: xIkke(mnr)"KD" [substitution]
    *** source: 21464307-Fig-1b
  *** Foxo13s[phosAb] phos(CTWPL)[phosAb] is increased itpo xTbk1
    *** cells: HELA in BMS
    *** inhibited by: xTbk1(mnr)"KD" [substitution]
    *** source: 21464307-Fig-1a
  *** Foxp3-gene mRNA[RTPCR] is detectable
    *** cells: hPBMCs<Cd4~pos><IL2Ra~pos> in BMS
    *** reqs: IL2Ra [altsort]
    *** source: 16645171-Fig-1a
  *** Foxp3-gene mRNA[RTPCR] is detectable
    *** cells: hPBMCs<Cd4~pos><IL2Ra~pos> in BMS
    *** reqs: IL2Ra [altsort]
    *** source: 16645171-Fig-1c
  *** Foxp3[Ab] prot-exp[WB] is detectable
    *** cells: hPBMCs<Cd4~pos><IL2Ra~pos> in BMS
    *** reqs: IL2Ra [altsort]
    *** source: 16645171-Fig-1b
  *** rFrat1[tAb] boundby[WB] rDvl1[MalBP] is detectable
    *** cells: none
    *** comment: reaction contains rCsnk1e
    *** comment: enhanced by addition of ATP to the reaction
    *** inhibited by: rFrat1(del(228-250)) [substitution]
    *** source: 12556519-Fig-2d
  *** xFrat1[tAb] copptby[WB] xDvl1[tAb] is detectable
    *** cells: COS<xDvl1><xFrat1><xCsnk1e> in BMS
    *** partially inhibited by: xCsnk1(mnr)"KD" [substitution]
    *** source: 12556519-Fig-2c
  *** xFrat1[tAb] copptby[WB] xDvl1[tAb] is detectable
    *** cells: COS<xDvl1><xFrat1><xCsnk1e> in BMS
    *** unaffected by: xFrat1(1-185) [substitution]
    *** source: 12556519-Fig-2c
  *** xFreud1[tAb] copptby[WB] xAkt1[tAb] is detectable
    *** cells: HEK293T<xFreud1><xAkt1> in BMS
    *** source: 18662999-Fig-4e
  *** xFreud1[tAb] copptby[WB] xAkt1[tAb] is detectable
    *** cells: HEK293T<xFreud1><xAkt1> in BMS
    *** unaffected by: xAkt1(E40K) [substitution]
    *** inhibited by: xAkt1(T308D) [substitution]
    *** unaffected by: xAkt1(S473D) [substitution]
    *** inhibited by: xAkt1(T308D/S473D) [substitution]
    *** source: 18662999-Fig-4c
  *** xFreud1[tAb] copptby[WB] xS6k1[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 18662999-Fig-4e
  *** xFreud1[tAb] copptby[WB] xS6k1[tAb] is undetectable
    *** cells: HEK293T<xFreud1><xS6k1> in BMS
    *** source: 18662999-Fig-4e
  *** xFrs2(1-158)[Ab] copptby[WB] xFgfR1[Ab] is detectable
    *** cells: HEK293<xFrs2(1-58)><xFgfR1> in BMS
    *** inhibited by: xFrs2(1-158/G2A) [substitution]
    *** source: 10629055-Fig-2a
  *** xFrs2[Ab] copptby[WB] xFgfR1[Ab] is detectable
    *** cells: HEK293<xFrs2><xFgfR1> in BMS
    *** unaffected by: xFgfR1(mnr)"KD" [substitution]
    *** source: 10629055-Fig-2a
  *** xFrs2[Ab] snaggedby[WB] rGab1[GST] is detectable
    *** cells: HEK293<xFgfR1> in BMS
    *** inhibited by: xFgfR1(mnr)"KD" [substitution]
    *** source: 11353842-Fig-2a
  *** xFrs2[Ab]IP ubiq[tUbAb] is detectable
    *** cells: HEK293T<xUbiq> in BMS
    *** unaffected by: xCbl [addition]
    *** source: 12815057-Fig-5b
  *** xFrs2[Ab]IP ubiq[tUbAb] is detectable
    *** cells: HEK293T<xUbiq> in BMS
    *** unaffected by: xFgfR1 [addition]
    *** source: 12815057-Fig-5b
  *** xFrs2[Ab]IP ubiq[tUbAb] is detectable
    *** cells: HEK293T<xUbiq> in BMS
    *** unaffected by: xSpry2 [addition]
    *** partially inhibited by: xSpry2(Y55F) [addition]
    *** source: 12815057-Fig-5b
  *** Frs2[Ab]IP Yphos[pYAb] is detectable
    *** cells: PC12NNR5<xTrka> in BMS
    *** inhibited by: xTrka(Y490F) [substitution]
    *** source: 15167895-Fig-5a
  *** xFrs2[Ab]IP Yphos[pYAb] is increased itpo xFgfR1
    *** cells: HEK293<xFrs2> in BMS
    *** inhibited by: xFgfR1(mnr)"KD" [substitution]
    *** source: 10629055-Fig-1c
  *** xFrs2[Ab]IP Yphos[pYAb] is increased itpo xFgfR1
    *** cells: HEK293<xFrs2> in BMS
    *** partially inhibited by: xFrs2(Y196F/Y306F/Y349F/Y392F) [substitution]
    *** unaffected by: xFrs2(Y436F) [substitution]
    *** inhibited by: xFrs2(Y196F/Y306F/Y349F/Y392F/Y436F) [substitution]
    *** source: 9632781-Fig-2a
  *** Fyn[Ab] copptby[WB] Ctnnd1[Ab] is detectable
    *** cells: IEC18 in BMS
    *** unaffected by: xKras(G12V)"CA" [addition]
    *** source: 12640114-Fig-6a
  *** Fyn[Ab] copptby[WB] Pag1[Ab] is undetectable
    *** cells: hPBTCs in BMS
    *** unaffected by: anti-Cd3 + anti-Cd28 (tnr) [stim]
    *** source: 10790433-Fig-9a
  *** xFyn[Ab] copptby[WB] xBcar1[tAb] is detectable
    *** cells: COS7<xBcar1> in BMS
    *** unaffected by: xBcar1(del(213-889))"delSD" [substitution]
    *** inhibited by: xBcar1(del(638-889))"delSrcBinding" [substitution]
    *** source: 9188452-Fig-3a
  *** Fyn[Ab] copptby[WB] xIL2Rb[Ab] is detectable
    *** cells: BAFB03<xIL2Rb> in BMS
    *** reqs: xIL2Rb [omission]
    *** source: 8483935-Fig-5b
  *** Fyn[Ab] copptby[WB] xIL2Rb[Ab] is detectable
    *** cells: BAFB03<xIL2Rb> in BMS
    *** source: 8483935-Fig-5a
  *** xFyn[Ab] copptby[WB] xPag1[tAb] is detectable
    *** cells: COS in BMS
    *** unaffected by: xPag1(Y317F) [substitution]
    *** source: 10790433-Fig-7e
  *** xFyn[Ab] copptby[WB] xStat3[GST] is detectable
    *** cells: SF9 in BMS
    *** source: 12244095-Fig-3
  *** Fyn[Ab] copptby[WB] Yes1[Ab] is increased itpo xKras(G12V)"CA"
    *** cells: IEC18 in BMS
    *** source: 12640114-Fig-7a
  *** xFyn[tAb]IP IVKA(Ctnnb1)[pYAb] is increased itpo xKras(G12V)"CA"
    *** cells: IEC18 in BMS
    *** source: 12640114-Fig-5d
  *** xFyn[tAb]IP Yphos[pYAb] is increased itpo xKras(G12V)"CA"
    *** cells: IEC18 in BMS
    *** source: 12640114-Fig-5c,6b
  *** xFzd7[tAb] copptby[WB] xRor2[tAb] is detectable
    *** cells: Lcells<xRor2><xFzd7> in BMS
    *** enhanced by: xRor2(mnr)"DK" [substitution]
    *** inhibited by: xRor2(mnr)"delCRD" [substitution]
    *** inhibited by: xRor2(mnr)"delC" [substitution]
    *** unaffected by: xRor2(mnr)"Tc" [substitution]
    *** source: 20457807-Fig-3a
  *** Apoptosis[FACS] is increased itpo xTp53
    *** cells: H1299<Tp53~null> in BMS
    *** inhibited by: xTp53(S33A/S46A) [substitution]
    *** source: 10581258-Fig-5a
*** Gab1--
  *** rGab1[32P] phos[32P-ATP] is increased by xHgfR[Ab]IP
    *** cells: none
    *** IPfrom: HEK293 in BMS
    *** source: 12941962-Fig-4a
  *** rGab1[32P] phos[32P-ATP] is unchanged by Csk[Ab]IP
    *** cells: none
    *** IPfrom: NIH3T3 in BMS
    *** source: 12941962-Fig-4a
  *** Gab1[Ab]IP Yphos[pYAb] is detectable
    *** cells: mEFs in BMS
    *** repressed by: Fak1 [KO]
    *** repressed by: Yes1 and/or Fyn [DKO]
    *** unaffected by: Yes1 and/or Fyn and/or Src [TKO]
    *** source: 19350053-Fig-3c
  *** Gab1[phosAb] phos(Y307)[phosAb] is detectable
    *** cells: mEFs in BMS
    *** repressed by: Fak1 [KO]
    *** repressed by: Yes1 and/or Fyn [DKO]
    *** reqs: Yes1 and/or Fyn and/or Src [TKO]
    *** source: 19350053-Fig-3c
  *** xGab1[phosAb] phos(Y307)[phosAb] is increased itpo xCrk
    *** cells: HEK293T in BMS
    *** source: 19350053-Fig-2
  *** xGab1[phosAb] phos(Y307)[phosAb] is increased itpo xCrk(mnr)"vCrk"
    *** cells: HEK293T in BMS
    *** source: 19350053-Fig-2
  *** xGab1[phosAb] phos(Y307)[phosAb] is increased itpo xCrkI
    *** cells: HEK293T in BMS
    *** source: 19350053-Fig-2
  *** xGab1[phosAb] phos(Y307)[phosAb] is increased itpo xCrkL
    *** cells: HEK293T in BMS
    *** source: 19350053-Fig-2
  *** xGab1[phosAb] phos(Y307)[phosAb] is increased itpo xLck
    *** cells: HEK293T in BMS
    *** source: 19350053-Fig-3a
  *** xGab1[phosAb] phos(Y307)[phosAb] is increased itpo xVegfR1
    *** cells: HEK293T in BMS
    *** source: 19350053-Fig-3a
  *** xGab1[phosAb] phos(Y307)[phosAb] is unchanged itpo xCrk
    *** cells: mEFs<Src~null><Yes1~null><Fyn~null> in BMS
    *** source: 19350053-Fig-3d
  *** xGab1[phosAb] phos(Y307)[phosAb] is unchanged itpo xCsk
    *** cells: HEK293T in BMS
    *** source: 19350053-Fig-3a
  *** xGab1[phosAb] phos(Y307)[phosAb] is unchanged itpo xFak1
    *** cells: HEK293T in BMS
    *** source: 19350053-Fig-3a
  *** xGab1[phosAb] phos(Y307)[phosAb] is unchanged itpo xGrb2
    *** cells: HEK293T in BMS
    *** source: 19350053-Fig-2
  *** xGab1[phosAb] phos(Y307)[phosAb] is unchanged itpo xShc1
    *** cells: HEK293T in BMS
    *** source: 19350053-Fig-2
  *** xGab1[phosAb] phos(Y307)[phosAb] is unchanged itpo xShp2
    *** cells: HEK293T in BMS
    *** source: 19350053-Fig-2
  *** xGab1[tAb]IP phos(Y307)[phosAb] is detectable
    *** cells: HEK293T<xCrk> in BMS
    *** inhibited by: xCrk(R38V) [substitution]
    *** unaffected by: xCrk(W139L) [substitution]
    *** unaffected by: xCrk(Y221F) [substitution]
    *** source: 19350053-Fig-1b
  *** xGab1[tAb]IP phos(Y307)[phosAb] is detectable
    *** cells: HEK293T<xCrk> in BMS
    *** inhibited by: xGab1(del(241-411)) [substitution]
    *** source: 19350053-Fig-1b
  *** xGab1[tAb]IP Yphos[pYAb] is detectable
    *** cells: HEK293T<xCrk> in BMS
    *** inhibited by: xCrk(R38V) [substitution]
    *** unaffected by: xCrk(W139L) [substitution]
    *** unaffected by: xCrk(Y221F) [substitution]
    *** source: 19350053-Fig-1b
  *** xGab1[tAb]IP Yphos[pYAb] is detectable
    *** cells: HEK293T<xCrk> in BMS
    *** inhibited by: xGab1(del(241-411)) [substitution]
    *** source: 19350053-Fig-1b
  *** xGab1[tAb]IP Yphos[pYAb] is detectable
    *** cells: PC12<xGab1> in BMLS
    *** unaffected by: PD98059 [addition]
    *** inhibited by: LY294002 [addition]
    *** source: 10601297-Fig-9c
  *** xGab1[tAb]IP Yphos[pYAb] is increased itpo xCrk
    *** cells: HEK293T in BMS
    *** source: 19350053-Fig-2
  *** xGab1[tAb]IP Yphos[pYAb] is increased itpo xCrk
    *** cells: HEK293T in BMS
    *** source: 19350053-Fig-4a
  *** xGab1[tAb]IP Yphos[pYAb] is increased itpo xCrk
    *** cells: mEFs<Src~null><Yes1~null><Fyn~null> in BMS
    *** source: 19350053-Fig-3d
  *** xGab1[tAb]IP Yphos[pYAb] is increased itpo xCrk(mnr)"vCrk"
    *** cells: HEK293T in BMS
    *** source: 19350053-Fig-2
  *** xGab1[tAb]IP Yphos[pYAb] is increased itpo xCrkI
    *** cells: HEK293T in BMS
    *** source: 19350053-Fig-2
  *** xGab1[tAb]IP Yphos[pYAb] is increased itpo xCrkL
    *** cells: HEK293T in BMS
    *** source: 19350053-Fig-2
  *** xGab1[tAb]IP Yphos[pYAb] is increased itpo xLck
    *** cells: HEK293T in BMS
    *** source: 19350053-Fig-3a
  *** xGab1[tAb]IP Yphos[pYAb] is unchanged itpo xCsk
    *** cells: HEK293T in BMS
    *** source: 19350053-Fig-3a
  *** xGab1[tAb]IP Yphos[pYAb] is unchanged itpo xFak1
    *** cells: HEK293T in BMS
    *** source: 19350053-Fig-3a
  *** xGab1[tAb]IP Yphos[pYAb] is unchanged itpo xGrb2
    *** cells: HEK293T in BMS
    *** source: 19350053-Fig-2
  *** xGab1[tAb]IP Yphos[pYAb] is unchanged itpo xShc1
    *** cells: HEK293T in BMS
    *** source: 19350053-Fig-2
  *** xGab1[tAb]IP Yphos[pYAb] is unchanged itpo xShp2
    *** cells: HEK293T in BMS
    *** source: 19350053-Fig-2
  *** xGab1[tAb]IP Yphos[pYAb] is unchanged itpo xVegfR1
    *** cells: HEK293T in BMS
    *** source: 19350053-Fig-3a
*** Gab2--
  *** rGab2(601-676)[GST] phos[32P-ATP] is increased by rErk1{act}
    *** cells: none
    *** comment: rErk2{act} is in the kinase reaction
    *** inhibited by: rGab2((601-676)/S623A) [substitution]
    *** comment: rGab2(601-676) was shown to be S623 by MS
    *** source: 15356145-Fig-2b
  *** rGab2(601-676)[GST] phos[32P-ATP] is increased by rErk1{act}
    *** cells: none
    *** inhibited by: rGab2((601-676)/S623A) [substitution]
    *** source: 15356145-Fig-2b
  *** Gab2[Ab] copptby[WB] Grap2[Ab] is undetectable
    *** cells: mBMfDCs in BMS "precultured for 6 days in Flt3L, then 2 days in Csf1"
    *** source: 11997510-Fig-8d
  *** Gab2[Ab] copptby[WB] Pik3rs[Ab] is detectable
    *** cells: NK33 in BMLS
    *** unaffected by: IL2 (5 min) [stim]
    *** source: 10849428-Fig-2
  *** Gab2[Ab] copptby[WB] xGrap2[Ab] is undetectable
    *** cells: FDCP1<xCsf1R> in BMLS
    *** source: 11997510-Fig-2a
  *** xGab2[Ab]IP Yphos[pYAb] is increased itao Csk [KO]
    *** cells: mEFs<xGab2> in BMLS
    *** source: 12464621-Fig-2b
  *** xGab2[tAb] copptby[WB] xHgfR[Ab] is detectable
    *** cells: HEK293T<xHgfR> in BMS
    *** unaffected by: xGab2(mnr)"delGrb2BD" [substitution]
    *** source: 12058075-Fig-4c
  *** xGab2[tAb] copptby[WB] xSfn[GST] is detectable
    *** cells: Ecoli<xGab2><xSfn> in BMS
    *** source: 19172738-Fig-S1a
  *** xGab2[tAb] copptby[WB] xYwhab[GST] is detectable
    *** cells: Ecoli<xGab2><xYwhab> in BMS
    *** source: 19172738-Fig-S1a
  *** xGab2[tAb] copptby[WB] xYwhae[GST] is detectable
    *** cells: Ecoli<xGab2><xYwhae> in BMS
    *** source: 19172738-Fig-S1a
  *** xGab2[tAb] copptby[WB] xYwhag[GST] is detectable
    *** cells: Ecoli<xGab2><xYwhag> in BMS
    *** source: 19172738-Fig-S1a
  *** xGab2[tAb] copptby[WB] xYwhah[GST] is detectable
    *** cells: Ecoli<xGab2><xYwhah> in BMS
    *** source: 19172738-Fig-S1a
  *** xGab2[tAb] copptby[WB] xYwhaq[GST] is detectable
    *** cells: Ecoli<xGab2><xYwhaq> in BMS
    *** source: 19172738-Fig-S1a
  *** xGab2[tAb] copptby[WB] xYwhaz[GST] is detectable
    *** cells: Ecoli<xGab2><xYwhaz> in BMS
    *** source: 19172738-Fig-S1a
  *** xGab2[tAb] snaggedby[WB] rYwhab[GST] is detectable
    *** cells: Ecoli<xGab2> in BMS
    *** source: 19172738-Fig-S1a
  *** xGab2[tAb]IP boundby[FarWestern] rYwhab[GST] is detectable
    *** cells: MCF10A<xGab2> in BMLS
    *** comment: binding is prevented by pretreating membrane with PPase
    *** source: 19172738-Fig-S1c
  *** xGab2[tAb]IP phos[WBMS] is increased itpo xMek1(S218D/S222D)"CA"
    *** cells: KIT225 in BMS "starved"
    *** partially inhibited by: xGab2(S623A) [substitution]
    *** source: 15356145-Fig-3
  *** xGab2[tAb]IP Yphos[pYAb] is increased itpo xJak3
    *** cells: HEK293T in BMS
    *** source: 10849428-Fig-6a
  *** xGab2[tAb]IP Yphos[pYAb] is increased itpo xLck
    *** cells: HEK293T in BMS
    *** enhanced by: xLck(mnr)"CA" [substitution]
    *** inhibited by: xLck(mnr)"KD" [substitution]
    *** source: 10849428-Fig-6a
  *** xGab2[tAb]IP Yphos[pYAb] is increased itpo xLck
    *** cells: HEK293T<xIL2Ra><xIL2Rb><xIL2Rg> in BMS
    *** source: 10849428-Fig-7d
  *** xGab2[tAb]IP Yphos[pYAb] is increased itpo xSyk
    *** cells: HEK293T in BMS
    *** source: 10849428-Fig-6a
  *** xGab2[tAb]IP Yphos[pYAb] is unchanged itpo Jak1
    *** cells: HEK293T<xIL2Ra><xIL2Rb><xIL2Rg> in BMS
    *** source: 10849428-Fig-7d
  *** Gab3[Ab] copptby[WB] Grap2[Ab] is detectable
    *** cells: mBMfDCs in BMS "precultured for 6 days in Flt3L, then 2 days in Csf1"
    *** source: 11997510-Fig-8c
  *** xGab3[tAb] copptby[WB] xCsf1R[Ab] is undetectable
    *** cells: FDCP1<xCsf1R> in BMLS
    *** unaffected by: Csf1 (2 min) [stim]
    *** source: 11997510-Fig-4
  *** xGab3[tAb] copptby[WB] xGrap2[Ab] is detectable
    *** cells: FDCP1<xCsf1R> in BMLS
    *** source: 11997510-Fig-2b
  *** Gadd45a-gene mRNA[RTPCR] is detectable
    *** cells: mEFs in BMS
    *** reqs: Egr1 [KO]
    *** source: 15958557-Fig-1
  *** Gadd45b[Ab] copptby[WB] Mekk1[Ab] is undetectable
    *** cells: 3DO in BMS
    *** unaffected by: PMA + Ionomycin [addition]
    *** source: 14743220-Fig-3
  *** rGadd45b[tAb] boundby[WB] rMkk7[GST] is detectable
    *** cells: none
    *** source: 14743220-Fig-3c
  *** GAS-reporter[Luc] is detectable
    *** cells: NIH3T3<xIL2Ra><xIL2Rb><xIL2Rg><Jak3~null><Lck~null><xJak3> in BMLS
    *** inhibited by: xShp2(mnr)"DN" [addition]
    *** source: 9590209-Fig-4b
  *** GAS-reporter[Luc] is increased itpo xCish(R107K)
    *** cells: 32D<xIL2Rb> in BMS
    *** source: 10514520-Fig-8b
  *** GAS-reporter[Luc] is increased itpo xShp2
    *** cells: NIH3T3<xIL2Ra><xIL2Rb><xIL2Rg><Jak3~null><Lck~null><xJak3> in BMLS
    *** source: 9590209-Fig-4a
  *** Gata3-gene mRNA[Northern] is detectable
    *** cells: mLCs<Cd4~pos><Lselectin~pos> in BMS "treated with anti-Cd3,anti-Cd28,IL4,anti-Ifng/IL2/anti-Cd3"
    *** reqs: Stat6 [KO]
    *** does not req: Irs2 [KO]
    *** source: 11739727-Fig-4b
  *** Gata3-gene mRNA[Northern] is undetectable
    *** cells: mLCs<Cd4~pos><Lselectin~pos> in BMS "treated with anti-Cd3,anti-Cd28,anti-IL4,IL12/IL2/PMA,Ionomycin"
    *** does not req: Stat6 [KO]
    *** does not req: Irs2 [KO]
    *** does not req: Irs2 or Stat6 [DKO]
    *** source: 11739727-Fig-4b
  *** Gata3-gene mRNA[RTPCR] is detectable
    *** cells: mSpCD4TCs in BMS "pretreated with anti-Cd3 + anti-Cd28 + IL12 for 5 days"
    *** reqs: Stat6 [KO]
    *** does not req: Tbet [KO]
    *** source: 19324016-Fig-3c
  *** Geft[Ab] copptby[WB] xCdkn1b[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 18851832-Fig-4e
  *** Geft[Ab] copptby[WB] xMlk2[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 18851832-Fig-4e
  *** xGeft[tAb] copptby[WB] xMlk3[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 18851832-Fig-4c
*** Gfi1--
  *** xGfi1[Ab] boundto(Cdkn1a-gene)[ChIP] is detectable
    *** cells: HEK293T<xGfi1><xZbtb17> in BMS
    *** reqs: xZbtb17 [omission]
    *** source: 20190815-Fig-2c
  *** Gfi1[Ab] boundto(Cdkn1a-gene)[ChIP] is detectable
    *** cells: HL60 in BMS
    *** reqs: Zbtb17 [RNAi]
    *** source: 20190815-Fig-2e
  *** Gfi1[Ab] boundto(Cdkn1a-gene)[ChIP] is detectable
    *** cells: HL60 in BMS
    *** source: 20190815-Fig-2d
  *** Gfi1[Ab] boundto(Cdkn1a-gene)[ChIP] is detectable
    *** cells: JURKAT in BMS
    *** source: 20190815-Fig-2d
  *** xGfi1[Ab] snaggedby[WB] oligo[biotin] is detectable
    *** cells: HEK293T<xGfi1><xZbtb17> in BMS
    *** inhibited by: xGfi1(mnr)"delZF6" [substitution]
    *** unaffected by: xGfi1(mnr)"delN" [substitution]
    *** source: 20190815-Fig-3c
  *** xGfi1[Ab] snaggedby[WB] oligo[biotin] is detectable
    *** cells: HEK293T<xGfi1><xZbtb17> in BMS
    *** reqs: xZbtb17 [omission]
    *** source: 20190815-Fig-2a
  *** xGfi1[Ab] snaggedby[WB] oligo[biotin] is detectable
    *** cells: HEK293T<xGfi1><xZbtb17> in BMS
    *** unaffected by: xGfi1(N382N) [substitution]
    *** source: 20190815-Fig-2b
  *** xGfi1[Ab] snaggedby[WB] oligo[biotin] is detectable
    *** cells: HEK293T<xGfi1><xZbtb17><xMyc> in BMS
    *** reqs: xZbtb17 [omission]
    *** source: 20190815-Fig-6b
*** Git1--
  *** xGit1[tAb]IP Yphos[pYAb] is increased itpo xSrc(Y527F)"CA"
    *** cells: HEK293 in BMLS
    *** source: 14701758-Fig-8a
  *** xGit1[tAb]IP Yphos[pYAb] is increased itpo xSrc(Y527F)"CA"
    *** cells: NIH3T3 in BMS
    *** source: 10428811-Fig-7b
  *** xGit2[tAb] copptby[WB] xArhGef6[tAb] is detectable
    *** cells: COS in BMS
    *** source: 10428811-Fig-4c
  *** xGit2[tAb] copptby[WB] xArhGef7[tAb] is detectable
    *** cells: COS in BMS
    *** unaffected by: xArhGef7(369-649) [substitution]
    *** source: 10428811-Fig-4c
  *** xGit2[tAb] copptby[WB] xArhGef7[tAb] is detectable
    *** cells: COS in BMS
    *** unaffected by: xArhGef7(W43K) [substitution]
    *** source: 10428811-Fig-4b
  *** xGit2[tAb] copptby[WB] xPak3[tAb] is undetectable
    *** cells: COS in BMS
    *** source: 10428811-Fig-4b
  *** xGit2[tAb] oligomerization[2TagPpt] is undetectable
    *** cells: COS in BMS
    *** source: 10428811-Fig-4c
  *** xGit2[tAb]IP Yphos[pYAb] is increased itpo xFak1
    *** cells: COS in BMS
    *** partially inhibited by: xFak1(K454R)"KD" [substitution]
    *** partially inhibited by: xFak1(Y397F) [substitution]
    *** source: 10428811-Fig-7a
  *** xGlut4[XFP] locatedin(cellmembrane)[IHC] is increased itpo xPik3c?(mnr)"CAAX"
    *** cells: 3T3L1 in BMS "differentiated into adipocytes"
    *** enhanced by: xRapGef1 [addition]
    *** source: 11309621-Fig-5b
  *** xGlut4[XFP] locatedin(cellmembrane)[IHC] is unchanged itpo xRapGef1
    *** cells: 3T3L1 in BMS "differentiated into adipocytes"
    *** source: 11309621-Fig-5b
  *** rGna12[Ab] boundby[WB] rRasa2[GST] is detectable
    *** cells: none
    *** source: 9796816-Fig-5a
  *** Gna12[Ab] copptby[WB] Btk[Ab] is detectable
    *** cells: DT40 in BMS
    *** source: 9796816-Fig-3b
  *** xGna12[Ab] copptby[WB] xRasa2[Ab] is detectable
    *** cells: COS7 in BMS
    *** source: 9796816-Fig-6b
  *** xGnao1[Ab] copptby[WB] xGsk3?[tAb] is undetectable
    *** cells: HEK293<xGsk3?><xGnao1> in BMS
    *** source: 20460648-Fig-S5
  *** xGnaq[Ab] copptby[WB] xGeft[GST] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xMlk3 [addition]
    *** unaffected by: xCdkn1b [addition]
    *** source: 18851832-Fig-6d
  *** rGnb1[35S] boundby[WB] rPak1[GST] is detectable
    *** cells: none
    *** source: 12887923-Fig-2d
  *** rGnb1[tAb] boundby[WB] rGsk3?[tAb] is detectable
    *** cells: none
    *** comment: reaction also contains rGng2
    *** source: 20460648-Fig-2d
  *** xGnb1[tAb] copptby[WB] xAdrbk?[tAb] is detectable
    *** cells: HEK293<xAdrbk?><xGnb1><xGng2> in BMS
    *** source: 20460648-Fig-S6
  *** xGnb1[tAb] copptby[WB] xGsk3?[tAb] is detectable
    *** cells: HEK293<xGsk3?><xGnb1><xGng2> in BMS
    *** source: 20460648-Fig-S5
  *** rGp130(605-918)[His] phos[32P-ATP] is increased by rPkcd
    *** cells: none
    *** source: 12361954-Fig-8a
  *** Gp130[Ab]IP Yphos[pYAb] is increased itpo xJak1
    *** cells: COS1 in BMS
    *** source: 15156153-Fig-2d
  *** Gp130[Ab]IP Yphos[pYAb] is unchanged itpo xHes1
    *** cells: COS1 in BMS
    *** source: 15156153-Fig-2d
  *** xGp130[tAb] copptby[WB] xLmo4[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15677447-Fig-1a
  *** xGp130[tAb] oligomerization[2TagPpt] is detectable
    *** cells: COS7 in BMS
    *** enhanced by: IL6 (tnr) [stim]
    *** source: 16774741-Fig-2c
  *** xGrap2[Ab] copptby[WB] Gab2[Ab] is undetectable
    *** cells: FDCP1<xCsf1R> in BMLS
    *** source: 11997510-Fig-2a
  *** xGrap2[Ab] copptby[WB] xGab3[tAb] is detectable
    *** cells: FDCP1<xCsf1R> in BMLS
    *** source: 11997510-Fig-2b
  *** Grb2[Ab] copptby[WB] Abi1[Ab] is detectable
    *** cells: A431 in BMLS "Triton-Insoluble fraction"
    *** unaffected by: Egf (5,30,120  min) [stim]
    *** source: 16775008-Fig-3c
  *** Grb2[Ab] copptby[WB] Abi1[Ab] is undetectable
    *** cells: COS7 in BMS
    *** source: 11777939-Fig-5[tl]
  *** Grb2[Ab] copptby[WB] Cbl[Ab] is detectable
    *** cells: 16E6P in BMS "Egf deprived"
    *** enhanced by: Egf (10 min) [stim]
    *** source: 8662998-Fig-4
  *** Grb2[Ab] copptby[WB] Cbl[Ab] is detectable
    *** cells: JURKATT in BMS
    *** unaffected by: anti-Cd3e (15 min) [stim]
    *** unaffected by: PMA (15 min) [stim]
    *** source: 9092538-Fig-1b
  *** Grb2[Ab] copptby[WB] Gab1[Ab] is detectable
    *** cells: PC12 in BMLS
    *** enhanced by: Fgf1 + Heparin (10 min) [stim]
    *** source: 11353842-Fig-2d
  *** Grb2[Ab] copptby[WB] Gab2[Ab] is detectable
    *** cells: mBMfDCs in BMS "precultured for 6 days in Flt3L, then 2 days in Csf1"
    *** source: 11997510-Fig-8d
  *** Grb2[Ab] copptby[WB] Grap2[Ab] is undetectable
    *** cells: mBMfDCs in BMS "precultured for 6 days in Flt3L, then 2 days in Csf1"
    *** source: 11997510-Fig-8d
  *** xGrb2[Ab] copptby[WB] Mekk1[Ab] is detectable
    *** cells: CCL39<xEgfR> in BMS
    *** source: 9733714-Fig-1b
  *** Grb2[Ab] copptby[WB] Mekk1[Ab] is detectable
    *** cells: CHO<xEgfR><xInsR> in BMS
    *** unaffected by: Egf (2,5,15 min) [stim]
    *** unaffected by: Btc (2,5,15 min) [stim]
    *** source: 15192046-Fig-8a
  *** Grb2[Ab] copptby[WB] Pak1[Ab] is detectable
    *** cells: HACAT in BMS
    *** source: 12522133-Fig-2a
  *** Grb2[Ab] copptby[WB] Pak1[Ab] is detectable
    *** cells: HACAT in BMS
    *** unaffected by: Egf (30 min) [stim]
    *** source: 12522133-Fig-3b
  *** Grb2[Ab] copptby[WB] Pak1[Ab] is detectable
    *** cells: JURKAT<Pten~null> in BMS
    *** source: 12522133-Fig-2a
  *** Grb2[Ab] copptby[WB] Shc1[Ab] is detectable
    *** cells: 16E6P in BMS "Egf deprived"
    *** source: 8662998-Fig-4
  *** Grb2[Ab] copptby[WB] Shc1[Ab] is increased itpo xFak2
    *** cells: HEK293T in BMS
    *** inhibited by: xFak2(Y402F) [substitution]
    *** unaffected by: xFak2(Y881F) [substitution]
    *** inhibited by: xFak2(mnr)"KD" [substitution]
    *** source: 10329689-Fig-2a
  *** Grb2[Ab] copptby[WB] Shp2[Ab] is increased itpo xFgfR1
    *** cells: HEK293 in BMS
    *** unaffected by: xFrs2 [addition]
    *** unaffected by: xFrs2(Y196F/Y306F/Y349F/Y392F) [addition]
    *** unaffected by: xFrs2(Y436F) [addition]
    *** unaffected by: xFrs2(Y196F/Y306F/Y349F/Y392F/Y436F) [addition]
    *** source: 9632781-Fig-2b
  *** Grb2[Ab] copptby[WB] Sos1[Ab] is detectable
    *** cells: NIH3T3 in BMLS
    *** unaffected by: Fgf1 + Heparin (5 min) [stim]
    *** source: 11353842-Fig-5a
  *** Grb2[Ab] copptby[WB] xFak2[Ab] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xFak2(Y402F) [substitution]
    *** inhibited by: xFak2(Y881F) [substitution]
    *** inhibited by: xFak2(mnr)"KD" [substitution]
    *** source: 10329689-Fig-2b
  *** Grb2[Ab] copptby[WB] xFrs2[Ab] is increased itpo xFgfR1
    *** cells: HEK293<xFrs2> in BMS
    *** partially inhibited by: xFrs2(Y196F/Y306F/Y349F/Y392F) [substitution]
    *** unaffected by: xFrs2(Y436F) [substitution]
    *** inhibited by: xFrs2(Y196F/Y306F/Y349F/Y392F/Y436F) [substitution]
    *** source: 9632781-Fig-2a
  *** Grb2[Ab] copptby[WB] xGab3[tAb] is undetectable
    *** cells: FDCP1<xCsf1R> in BMLS
    *** source: 11997510-Fig-2b
  *** Grb2[Ab] copptby[WB] xGrap2[Ab] is undetectable
    *** cells: FDCP1<xCsf1R><xGab3> in BMLS
    *** source: 11997510-Fig-2b
  *** Grb2[Ab] copptby[WB] xPik3c2b[tAb] is detectable
    *** cells: A431 in BMLS "Triton-Soluble fraction"
    *** unaffected by: Egf (10 min) [stim]
    *** source: 16775008-Fig-2d
  *** Grb2[Ab] copptby[WB] xSh2b1[Ab] is detectable
    *** cells: HEK293<xSh2b1> in BMS
    *** inhibited by: xSh2b1(del(384-504))"M7" [substitution]
    *** source: 9856458-Fig-5c
  *** Grb2[Ab] copptby[WB] xSh2b1[Ab] is detectable
    *** cells: HEK293<xSh2b1> in BMS
    *** unaffected by: xSh2b1(Y55F/Y751F)"M1" [substitution]
    *** unaffected by: xSh2b1(30-756/Y751F)"M2" [substitution]
    *** unaffected by: xSh2b1(30-756/Y55F/Y751F)"M3" [substitution]
    *** partially inhibited by: xSh2b1(396-756)"M4" [substitution]
    *** inhibited by: xSh2b1(500-756)"M5" [substitution]
    *** unaffected by: xSh2b1(30-537)"M6" [substitution]
    *** source: 9856458-Fig-5b
  *** Grb2[Ab] copptby[WB] xSos1[tAb] is detectable
    *** cells: COS1 in BMS
    *** enhanced by: xSos1(S1167A/S1178A/S1193A/S1132A) [substitution]
    *** source: 8816480-Fig-5f
  *** Grb2[Ab] copptby[WB] xSos2[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 8816480-Fig-6c
  *** Grb2[Ab] copptby[WB] xTnk2[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 8647288-Fig-4a
  *** Grb2[Ab] snaggedby[WB] rGab1[GST] is detectable
    *** cells: HEK293<xFgfR1> in BMS
    *** unaffected by: xFgfR1(mnr)"KD" [substitution]
    *** source: 11353842-Fig-2a
  *** Grb2[Ab]IP IVLKA(PtdIns/PI4P/PI45P2)[TLC] is detectable
    *** cells: A431<xPik3c2b> in BMLS
    *** unaffected by: Egf (5 min) [stim]
    *** source: 16775008-Fig-3e
  *** xGrb2[tAb] copptby[WB] xEps15[tAb] is detectable
    *** cells: HEK293<xEps15><xGrb2> in BMS
    *** unaffected by: xEps15(360-896)"dI" [substitution]
    *** unaffected by: xEps15(del(361-643))"dII" [substitution]
    *** inhibited by: xEps15(648-896)"dIII" [substitution]
    *** unaffected by: xEps15(813-896)"dIV" [substitution]
    *** unaffected by: xEps15(Y850F) [substitution]
    *** partially inhibited by: xEps15(P770A) [substitution]
    *** source: 19109251-Fig-4d
  *** xGrb2[tAb] copptby[WB] xEps15[tAb] is detectable
    *** cells: HEK293<xEps15><xGrb2> in BMS
    *** unaffected by: xHgfR [addition]
    *** source: 19109251-Fig-4b
  *** xGrb2[tAb] copptby[WB] xGab1[Ab] is detectable
    *** cells: HEK293<xGab1><xGrb2> in BMS "treated with Hgf + PAO for tnr"
    *** inhibited by: xGab1(del(340-347)/L524P) [substitution]
    *** unaffected by: xGab1(V489A) [substitution]
    *** source: 10871282-Fig-1d
  *** xGrb2[tAb] copptby[WB] xGab1[Ab] is detectable
    *** cells: HEK293<xGab1><xGrb2> in BMS "treated with Hgf + PAO for tnr"
    *** source: 10871282-Fig-2b
  *** xGrb2[tAb] copptby[WB] xGab2[Ab] is undetectable
    *** cells: HEK293<xGab2><xGrb2> in BMS "treated with Hgf + PAO for tnr"
    *** source: 10871282-Fig-2b
  *** xGrb2[tAb] copptby[WB] xRalGps1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 10747847-Fig-4c
  *** xGrb2[tAb] copptby[WB] xStat3[tAb] is undetectable
    *** cells: COS1 in BMS
    *** unaffected by: Egf (tnr) [stim]
    *** source: 14498832-Fig-3
  *** xGrb2[tAb] copptby[WB] xUsp6nl[tAb] is detectable
    *** cells: COS in BMLS
    *** unaffected by: Egf (10 min) [stim]
    *** source: 12399475-Fig-4a
  *** xGrb7[tAb] copptby[WB] xHras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xHras(G12V/D38A) [substitution]
    *** inhibited by: xHras(G12V/T35S) [substitution]
    *** inhibited by: xHras(G12V/E37G) [substitution]
    *** inhibited by: xHras(G12V/Y40C) [substitution]
    *** inhibited by: xHras(G12V/D38E) [substitution]
    *** source: 15143186-Fig-6
  *** xGrb7[tAb] copptby[WB] xHras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186(D)
  *** xGrb7[tAb] copptby[WB] xKras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xGrb7[tAb] copptby[WB] xMras(Q71L)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xGrb7[tAb] copptby[WB] xNras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xGrb7[tAb] copptby[WB] xRap1a(G12V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xGrb7[tAb] copptby[WB] xRap2a(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xGrb7[tAb] copptby[WB] xRras(G38V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xGrb7[tAb] copptby[WB] xRras2(G23V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xGsk3?[Ab] copptby[WB] xAdrbk?[tAb] is undetectable
    *** cells: HEK293<xAdrbk?><xGsk3?> in BMS
    *** source: 20460648-Fig-S6
  *** xGsk3?[tAb] copptby[WB] (xGnb1[tAb] + xGng2[tAb]) is detectable
    *** cells: HEK293<xGsk3?><xGnb1><xGng2> in BMS
    *** source: 20460648-Fig-2c
  *** xGsk3?[tAb] copptby[WB] xGnb1[tAb] is detectable
    *** cells: HEK293<xGsk3?><xGnb1><xGng2> in BMS
    *** enhanced by: xGnb1(K57A) [substitution]
    *** enhanced by: xGnb1(Y59A) [substitution]
    *** enhanced by: xGnb1(K78A) [substitution]
    *** unaffected by: xGnb1(W99A) [substitution]
    *** unaffected by: xGnb1(T143A) [substitution]
    *** enhanced by: xGnb1(Y145A) [substitution]
    *** unaffected by: xGnb1(D186A) [substitution]
    *** enhanced by: xGnb1(M188A) [substitution]
    *** enhanced by: xGnb1(N230A) [substitution]
    *** unaffected by: xGnb1(W322A) [substitution]
    *** source: 20460648-Fig-5b
  *** xGsk3?[tAb] infraction(membrane)[WB] is decreased itpo xAdrbk?(mnr)"Cterm"
    *** cells: HEK293<xGsk3?> in BMS
    *** partially reversed by: xGnb1 + xGng2 [addition]
    *** source: 20460648-Fig-2e
  *** xGsk3?[tAb] infraction(membrane)[WB] is increased itpo xGnb1 + xGng2
    *** cells: HEK293<xGsk3?> in BMS
    *** source: 20460648-Fig-2e
*** Gsk3a--
  *** Gsk3a[Ab] copptby[WB] xAxin1[tAb] is detectable
    *** cells: COS<xAxin1> in BMS
    *** source: 9482734-Fig-2c
  *** Gsk3a[Ab] prot-exp[WB] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: Gsk3b [RNAi]
    *** source: 11955436-Fig-6f
  *** Gsk3a[phosAb] phos(S21)[phosAb] is detectable
    *** cells: mESCs in BMLS
    *** reqs: Pdpk1 [KO]
    *** partially inhibited by: kPdpk1(L155E) [substitution]
    *** source: 12912918-Fig-3
  *** Gsk3a[phosAb] phos(S21)[phosAb] is detectable
    *** cells: mESCs in BMLS
    *** unaffected by: Msk1 [KO]
    *** source: 11018520-Fig-4d
  *** Gsk3a[phosAb] phos(S21)[phosAb] is detectable
    *** cells: RAW2647 in BMS
    *** unaffected by: PD184352 [addition]
    *** inhibited by: Wortmannin [addition]
    *** source: 12881422-Fig-4b
*** Gsk3b--
  *** Gsk3b[Ab] copptby[WB] Ctnnb1[Ab] is detectable-but unchanged itpo xPin1
    *** cells: HELA in BMS
    *** source: 11533658-Fig-6a
  *** Gsk3b[Ab] copptby[WB] Myc[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 19131971-Fig-1b
  *** Gsk3b[Ab] copptby[WB] Sp1[Ab] is undetectable
    *** cells: HEK293 in BMS
    *** source: 19131971-Fig-1b
  *** Gsk3b[Ab] copptby[WB] xDvl1[tAb] is detectable
    *** cells: COS<xDvl1><xFrat1><xCsnk1e> in BMS
    *** inhibited by: xFrat1(1-185) [substitution]
    *** source: 12556519-Fig-2c
  *** Gsk3b[Ab] copptby[WB] xDvl1[tAb] is detectable
    *** cells: COS<xDvl1><xFrat1><xCsnk1e> in BMS
    *** partially inhibited by: xCsnk1(mnr)"KD" [substitution]
    *** source: 12556519-Fig-2c
  *** Gsk3b[Ab] copptby[WB] xMyc[Ab] is detectable
    *** cells: HEK293<xAxin1><xMyc> in BMS
    *** inhibited by: xMyc(mnr)"delTAD" [substitution]
    *** source: 19131971-Fig-5a
  *** Gsk3b[Ab] copptby[WB] xMyc[Ab] is detectable
    *** cells: HEK293<xMyc> in BMS
    *** partially reqs: Axin1 [RNAi]
    *** source: 19131971-Fig-2d
  *** Gsk3b[Ab] copptby[WB] xMyc[Ab] is increased itpo xAxin1
    *** cells: HEK293<xMyc> in BMS
    *** source: 19131971-Fig-2e
  *** Gsk3b[Ab] prot-exp[WB] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: Gsk3b [RNAi]
    *** source: 11955436-Fig-6f
  *** rGsk3b[GST] IVKA(peptide)[32P-ATP] is detectable
    *** cells: none
    *** unaffected by: rAxin1 [addition]
    *** source: 10330181-Fig-6d
  *** rGsk3b[GST] IVKA(peptide)[32P-ATP] is detectable
    *** cells: none
    *** unaffected by: rDvl1 [addition]
    *** source: 10330181-Fig-6d
  *** Gsk3b[phosAb] phos(S9)[phosAb] is detectable
    *** cells: bAECs in BMLS
    *** reqs: Rac1 [RNAi]
    *** source: 16339142(D)
  *** Gsk3b[phosAb] phos(S9)[phosAb] is detectable
    *** cells: HEK293 in BMS
    *** does not req: Mtor [RNAi]
    *** source: 17043309-Fig-2b
  *** Gsk3b[phosAb] phos(S9)[phosAb] is detectable
    *** cells: HEK293 in BMS
    *** does not req: Raptor [RNAi]
    *** source: 17043309-Fig-2b
  *** Gsk3b[phosAb] phos(S9)[phosAb] is detectable
    *** cells: HEK293 in BMS
    *** does not req: Rictor [RNAi]
    *** source: 17043309-Fig-2b
  *** Gsk3b[phosAb] phos(S9)[phosAb] is detectable
    *** cells: HEK293 in BMS
    *** does not req: Sin1 [RNAi]
    *** source: 17043309-Fig-2b
  *** Gsk3b[phosAb] phos(S9)[phosAb] is detectable
    *** cells: HEK293 in BMS
    *** reqs: Ilk [RNAi]
    *** source: 12686550-Fig-2b
  *** Gsk3b[phosAb] phos(S9)[phosAb] is detectable
    *** cells: HELA in BMS
    *** does not req: Mtor [RNAi]
    *** source: 17043309-Fig-2a
  *** Gsk3b[phosAb] phos(S9)[phosAb] is detectable
    *** cells: HELA in BMS
    *** does not req: Raptor [RNAi]
    *** source: 17043309-Fig-2a
  *** Gsk3b[phosAb] phos(S9)[phosAb] is detectable
    *** cells: HELA in BMS
    *** reqs: Rictor [RNAi]
    *** source: 17043309-Fig-2a
  *** Gsk3b[phosAb] phos(S9)[phosAb] is detectable
    *** cells: HELA in BMS
    *** reqs: Sin1 [RNAi]
    *** source: 17043309-Fig-2a
  *** Gsk3b[phosAb] phos(S9)[phosAb] is detectable
    *** cells: mBMMs in BMS "immortalized"
    *** reqs: Ilk [RNAi]
    *** source: 12686550-Fig-3b
  *** Gsk3b[phosAb] phos(S9)[phosAb] is detectable
    *** cells: mESCs in BMLS
    *** reqs: Pdpk1 [KO]
    *** partially inhibited by: kPdpk1(L155E) [substitution]
    *** source: 12912918-Fig-3
  *** Gsk3b[phosAb] phos(S9)[phosAb] is detectable
    *** cells: RAW2647 in BMS
    *** unaffected by: PD184352 [addition]
    *** inhibited by: Wortmannin [addition]
    *** source: 12881422-Fig-4b
  *** Gsk3b[phosAb] phos(S9)[phosAb] is increased itao Cav1 [RNAi]
    *** cells: bAECs in BMLS
    *** source: 15292187(D)
  *** Gsk3b[phosAb] phos(S9)[phosAb] is increased itao Cav1 [RNAi]
    *** cells: bAECs in BMLS
    *** source: 17519230(D)
  *** Gsk3b[phosAb] phos(S9)[phosAb] is unchanged itpo xDvl2
    *** cells: HEK293<xS6k1> in BMS
    *** source: 16959574-Fig-4b
  *** Gsk3b[phosAb] phos(S9)[phosAb] is unchanged itpo xDvl2
    *** cells: HEK293<xS6k1> in BMS "Glucose-deprived"
    *** source: 16959574-Fig-4b
  *** xGsk3b[tAb] copptby[WB] xLrp5(1370-1615)"C2"[tAb] is detectable
    *** cells: COS7<xAxin1><xLrp5(1370-1615)> in BMS
    *** source: 11336703-Fig-3e
  *** xGsk3b[tAb] copptby[WB] xLrp5(1419-1615)"C3"[tAb] is detectable
    *** cells: COS7<xAxin1><xLrp5(1419-1615)> in BMS
    *** source: 11336703-Fig-3e
  *** xGsk3b[tAb]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: HEK293 in BMS
    *** source: 12559944-Fig-4a
*** Gsk3s--
  *** pGsk3s[32P] IVKA(Jun)[32P-ATP] is decreased by pRsk1
    *** cells: none
    *** comment: reversed by treatment with PP2A
    *** source: 8250835-Fig-2
  *** pGsk3s[32P] IVKA(peptide)[32P-ATP] is decreased by pRsk1
    *** cells: none
    *** comment: reversed by treatment with PP2A
    *** source: 8250835-Fig-2
  *** pGsk3s[32P] IVKA(peptide)[32P-ATP] is decreased by rS6k1
    *** cells: none
    *** comment: reversed by treatment with PP2A
    *** source: 8250835-Fig-2
  *** pGsk3s[32P] phos[32P-ATP] is increased by pRsk1
    *** cells: none
    *** comment: phos site was shown to be SFAE by chromatography
    *** source: 8250835-Fig-3
  *** pGsk3s[32P] phos[32P-ATP] is increased by pRsk1
    *** cells: none
    *** source: 8250835-Fig-1
  *** pGsk3s[32P] phos[32P-ATP] is increased by rS6k1
    *** cells: none
    *** source: 8250835-Fig-1
  *** Gsk3s[phosAb] phos(SFAE)[phosAb] is detectable
    *** cells: HELA<xTbk1> in BMS
    *** does not req: Mtor [RNAi]
    *** does not req: Rictor [RNAi]
    *** source: 21464307-Fig-S5a
  *** Gsk3s[phosAb] phos(SFAE)[phosAb] is detectable
    *** cells: HELA<xTbk1> in BMS
    *** inhibited by: xTbk1(mnr)"KD" [substitution]
    *** source: 21464307-Fig-S5a
  *** Gsk3s[phosAb] phos(SFAE)[phosAb] is detectable
    *** cells: HEPG2 in BMLS "plated on collagen"
    *** partially inhibited by: Gefitinib [cotreatment]
    *** partially inhibited by: PD325901 [cotreatment]
    *** partially inhibited by: BMS345541 [cotreatment]
    *** partially inhibited by: PHA818637 [cotreatment]
    *** partially inhibited by: ZSTK474 [cotreatment]
    *** source: 19953085-Fig-S1
  *** Gsk3s[phosAb] phos(SFAE)[phosAb] is increased itpo xIkke
    *** cells: HELA in BMS
    *** inhibited by: xIkke(mnr)"KD" [substitution]
    *** source: 21464307-Fig-1b
  *** Gsk3s[phosAb] phos(SFAE)[phosAb] is increased itpo xTbk1
    *** cells: HELA in BMS
    *** inhibited by: xTbk1(mnr)"KD" [substitution]
    *** source: 21464307-Fig-1a
*** Gtf2b--
  *** Gtf2b[Ab] snaggedby[WB] rElk1(307-428){phos}[Gal4-DBD-G5TATA] is detectable
    *** cells: mESCs in BMS "nuclear extracts"
    *** inhibited by: rElk1(307-428) [substitution]
    *** source: 14506297-Fig-3
  *** Gtf2b[Ab] snaggedby[WB] rElk1(307-428){phos}[Gal4-DBD-G5TATA] is detectable
    *** cells: mESCs in BMS "nuclear extracts"
    *** reqs: Med23 [KO]
    *** source: 14506297-Fig-3
  *** Gtf2b[Ab] snaggedby[WB] rMyc[GST] is undetectable
    *** cells: HELA in BMS "nuclear-extracts"
    *** source: 12660246-Fig-2a
  *** Gtf2e1[Ab] snaggedby[WB] rElk1(307-428){phos}[Gal4-DBD-G5TATA] is detectable
    *** cells: mESCs in BMS "nuclear extracts"
    *** inhibited by: rElk1(307-428) [substitution]
    *** source: 14506297-Fig-3
  *** Gtf2e1[Ab] snaggedby[WB] rElk1(307-428){phos}[Gal4-DBD-G5TATA] is detectable
    *** cells: mESCs in BMS "nuclear extracts"
    *** reqs: Med23 [KO]
    *** source: 14506297-Fig-3
*** H2ax--
  *** rH2ax(133-143)[phosAb] phos(S140)[phosAb] is increased by xAtm[tAb]IP
    *** cells: none
    *** IPfrom: HEK293T<xAtm> in BMS
    *** enhanced by: rMre11 + rRad50 + rNbs1 [addition]
    *** source: 15064416-Fig-2i
  *** xH2ax[tAb]IP ubiq[tUbAb] is detectable
    *** cells: HEK293T<xH2ax><xUbiq> in BMS
    *** source: 18001825-Fig-6a
  *** H2ax{phos(S140)}[phosAb] locatedin(DSBs)[IHC] is detectable
    *** cells: mEFs in BMS
    *** comment: seen at both 5 min and 4 hr post UV
    *** does not req: Mdc1 [KO]
    *** source: 16427009-Fig-6a
*** Hbegf--
  *** rHbegf[125I] copptby[Xlink] xEgfR[Ab] is detectable
    *** cells: NIH3T3<xEgfR> in BMS
    *** source: 9135143-Fig-1a
  *** rHbegf[125I] copptby[Xlink] xErbb2[Ab] is undetectable
    *** cells: NIH3T3<xErbb2> in BMS
    *** source: 9135143-Fig-1a
  *** rHbegf[125I] copptby[Xlink] xErbb3[Ab] is undetectable
    *** cells: NIH3T3<xErbb3> in BMS
    *** source: 9135143-Fig-1a
  *** rHbegf[125I] copptby[Xlink] xErbb4[Ab] is detectable
    *** cells: NIH3T3<xErbb4> in BMS
    *** inhibited by: anti-Erbb4 [pretreatment]
    *** unaffected by: anti-EgfR [pretreatment]
    *** source: 9135143-Fig-1b
  *** rHbegf[125I] copptby[Xlink] xErbb4[Ab] is detectable
    *** cells: NIH3T3<xErbb4> in BMS
    *** source: 9135143-Fig-1a
  *** Hbp1[Ab] copptby[WB] Myc[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 20008325-Fig-1d
  *** Hbp1[Ab] copptby[WB] Sp1[Ab] is undetectable
    *** cells: HEK293 in BMS
    *** source: 20008325-Fig-1d
  *** xHbp1[tAb] copptby[WB] xMyc[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 20008325-Fig-1b
  *** xHbp1[tAb] copptby[WB] xMyc[tAb] is detectable
    *** cells: HEK293<xMyc><xHbp1> in BMS
    *** inhibited by: xMyc(1-382)"delCT" [substitution]
    *** unaffected by: xMyc(mnr)"delMB1" [substitution]
    *** inhibited by: xMyc(mnr)"delMB2" [substitution]
    *** inhibited by: xMyc(mnr)"delTAD" [substitution]
    *** source: 20008325-Fig-4b
  *** xHck(Y522F)[phosAb] phos(Y390)[phosAb] is detectable
    *** cells: RAT2 in BMS
    *** inhibited by: xHck [substitution]
    *** inhibited by: xHck(W93A)"SH3-domain-mut" [substitution]
    *** inhibited by: xHck(mnr)"KD" [substitution]
    *** source: 12244095-Fig-6
  *** xHck[Ab] copptby[WB] xStat3[GST] is detectable
    *** cells: SF9 in BMS
    *** source: 12244095-Fig-3
  *** xHck[Ab]IP IVKA(Khdrbs1)[32P-ATP] is increased itpo xStat3
    *** cells: RAT2 in BMS
    *** source: 12244095-Fig-6
  *** Hdac1[Ab] boundto(Gbp2-gene)[ChIP] is increased itao Irf1 [KO]
    *** cells: mEFs in BMS
    *** comment: both proximal and distal promoter regions were examined
    *** source: 17293456-Fig-3e
  *** Hdac1[Ab] copptby[WB] Smad7[Ab] is detectable
    *** cells: HEK293T in BMS
    *** source: 15831498-Fig-2c
  *** xHdac1[tAb] copptby[WB] xElk1[tAb] is increased itpo xMek1(mnr)"CA"
    *** cells: HEK293<xHdac1><xElk1> in BMS
    *** source: 11283259-Fig-4c
  *** xHdac1[tAb] copptby[WB] xPias4[tAb] is detectable
    *** cells: COS in BMS
    *** unaffected by: xTgfbR1(T407D)"CA" [addition]
    *** source: 12904571-Fig-6a
  *** Hdac2[Ab] boundto(Fos-gene)[ChIP] is decreased itpo xPias2a
    *** cells: HEK293 in BMLS
    *** reversed by: xPias2a(del(467-487)) [substitution]
    *** source: 15920481-Fig-8f
  *** Hdac2[tAb] boundto(Egr1-gene)[ChIP] is detectable
    *** cells: HELA in BMS
    *** inhibited by: PMA [addition]
    *** source: 14992729-Fig-4e
  *** Hdac2[tAb] boundto(Egr1-gene)[ChIP] is detectable
    *** cells: HELA in BMS
    *** inhibited by: xUbe2i(mnr)"DN" [addition]
    *** source: 14992729-Fig-4e
  *** Hdac3[Ab] boundto(CcL2-gene)[ChIP] is detectable
    *** cells: mEFs in BMS
    *** reqs: Jun [KO]
    *** source: 18443042-Fig-8b
  *** Hdac3[Ab] copptby[WB] Jun[Ab] is detectable
    *** cells: mEFs in BMLS "nuclear-extracts"
    *** unaffected by: IL1a (1 hr) [stim]
    *** source: 18443042-Fig-10d
  *** Hdac3[Ab] copptby[WB] Jun{phos(S73)}[phosAb] is detectable
    *** cells: mEFs in BMLS "nuclear-extracts"
    *** inhibited by: IL1a (1 hr) [stim]
    *** source: 18443042-Fig-10d
  *** xHes1[tAb]IP IVKA(Stat3)(S705)[phosAb] is detectable
    *** cells: COS1 in BMS
    *** source: 15156153-Fig-4a
  *** xHes5[tAb]IP IVKA(Stat3)(S705)[phosAb] is detectable
    *** cells: COS1 in BMS
    *** source: 15156153-Fig-4a
  *** HgfR[Ab] copptby[WB] xGab1[Ab] is detectable
    *** cells: HEK293<xGab1><xGrb2> in BMS "treated with Hgf + PAO for tnr"
    *** partially inhibited by: xGab1(del(340-347)/L524P) [substitution]
    *** inhibited by: xGab1(V489A) [substitution]
    *** source: 10871282-Fig-1d
  *** HgfR[Ab] copptby[WB] xGab1[Ab] is detectable
    *** cells: HEK293<xGab1><xGrb2> in BMS "treated with Hgf + PAO for tnr"
    *** source: 10871282-Fig-2b
  *** HgfR[Ab] copptby[WB] xGab2[Ab] is undetectable
    *** cells: HEK293<xGab2><xGrb2> in BMS "treated with Hgf + PAO for tnr"
    *** source: 10871282-Fig-2b
  *** HgfR[Ab] secretion[ELISA] is unchanged itao Adam17 [RNAi]
    *** cells: MDAMB231 in BMS "treated with Cetuximab 30 min"
    *** source: 23720309-Fig-S1c
  *** xHgfR[Ab]IP Yphos[pYAb] is detectable
    *** cells: HEK293<xEps15> in BMS
    *** inhibited by: xHgfR(K110A) [substitution]
    *** source: 19109251-Fig-2f
  *** xHgfR[Ab]IP Yphos[pYAb] is detectable
    *** cells: HEK293<xEps15> in BMS
    *** unaffected by: xEps15(Y805F) [substitution]
    *** source: 19109251-Fig-2f
  *** HgfR[phosAb] phos(Y1234/Y1235)[phosAb] is increased itpo xSrc(mnr)"vSrc"
    *** cells: HEK293<xGab1> in BMLS
    *** source: 12941962-Fig-3a
  *** HgfR[phosAb] phos(Y1234/Y1235)[phosAb] is increased itpo xSrc(mnr)"vSrc"
    *** cells: NIH3T3 in BMLS
    *** inhibited by: xSrc [substitution]
    *** source: 12941962-Fig-3b
  *** HgfR[phosAb] phos(Y1234/Y1235)[phosAb] is increased itpo xSrc(Y527F)"CA"
    *** cells: HEK293<xGab1> in BMLS
    *** source: 12941962-Fig-3a
  *** HgfR[phosAb] phos(Y1234/Y1235)[phosAb] is increased itpo xSrc(Y527F)"CA"
    *** cells: NIH3T3 in BMLS
    *** inhibited by: xSrc [substitution]
    *** source: 12941962-Fig-3b
  *** xHgfR[tAb] copptby[WB] xEps15[tAb] is detectable
    *** cells: HEK293<xEps15><xHgfR> in BMS
    *** unaffected by: xEps15(360-896)"dI" [substitution]
    *** inhibited by: xEps15(del(361-643))"dII" [substitution]
    *** inhibited by: xEps15(648-896)"dIII" [substitution]
    *** unaffected by: xEps15(813-896)"dIV" [substitution]
    *** unaffected by: xEps15(Y850F) [substitution]
    *** source: 19109251-Fig-3a
  *** xHgfR[tAb] copptby[WB] xEps15[tAb] is detectable
    *** cells: HEK293<xEps15><xHgfR> in BMS
    *** unaffected by: xHgfR(Y1003F) [substitution]
    *** source: 19109251-Fig-3d
  *** xHgs[tAb] copptby[WB] xSmad2[tAb] is detectable
    *** cells: HEK293T<xAcvR2><xAcvR1b> in BMS
    *** enhanced by: xSara [addition]
    *** source: 11094085(D)
  *** xHgs[tAb] copptby[WB] xTsg101[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12802020(D)
  *** xHgs[tAb] copptby[Xlink] xSmad1[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 11094085(D)
  *** xHgs[tAb] copptby[Xlink] xSmad2[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 11094085(D)
  *** xHgs[tAb] copptby[Xlink] xSmad3[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 11094085(D)
  *** xHgs[tAb] copptby[Xlink] xSmad4[tAb] is undetectable
    *** cells: COS7 in BMS
    *** source: 11094085(D)
  *** xHgs[tAb] copptby[Xlink] xSmad6[tAb] is undetectable
    *** cells: COS7 in BMS
    *** source: 11094085(D)
  *** xHgs[tAb] snaggedby[WB] rUbiq{poly}[GST] is detectable
    *** cells: COS7 in BMS
    *** source: 17182860-Fig-8c
  *** xHgs[XFP] colocwith[IHC] M6pR[Ab] is detectable
    *** cells: HELA in BMLS
    *** unaffected by: xHgs(Y329F/Y334F) [substitution]
    *** inhibited by: xHgs(mnr)"UIM-domain-mut" [substitution]
    *** source: 12953068(D)
  *** xHgs[XFP] colocwith[IHC] TfRc[Ab] is detectable
    *** cells: HELA in BMLS
    *** unaffected by: xHgs(Y329F/Y334F) [substitution]
    *** inhibited by: xHgs(mnr)"UIM-domain-mut" [substitution]
    *** source: 12953068(D)
  *** Hif1a prot-exp[WB] is decreased itpo xRac1(T17N)
    *** cells: B16F10 in BMS
    *** source: 18003981-Fig-5d
  *** Hif1a prot-exp[WB] is decreased itpo xRac1(T17N)
    *** cells: B16F10 in BMS "treated with IL18 for 6 hr"
    *** source: 18003981-Fig-5b
  *** Hif1a prot-exp[WB] is detectable
    *** cells: B16F10 in BMS
    *** reqs: Rac1 [RNAi]
    *** source: 18003981-Fig-5d
  *** Hif1a prot-exp[WB] is detectable
    *** cells: B16F10 in BMS
    *** reqs: Rela [RNAi]
    *** source: 18003981-Fig-7a
  *** Hif1a prot-exp[WB] is increased itpo xHras(G12V)
    *** cells: B16F10 in BMS
    *** source: 18003981-Fig-5b
  *** Hif1a prot-exp[WB] is increased itpo xHras(G12V)
    *** cells: B16F10 in BMS
    *** source: 18003981-Fig-5d
*** Hif1a--
  *** Hif1a-gene mRNA[RTPCR] is increased itpo xJun
    *** cells: CHANG in BMS
    *** source: 17451682-Fig-3b
  *** Hif1a-gene mRNA[RTPCR] is unchanged itpo xJun
    *** cells: CHANG in BMS
    *** source: 17451682-Fig-4a
  *** Hif1a-gene promo-reporter[Luc] is increased itpo xJun
    *** cells: CHANG in BMS
    *** partially inhibited by: xJun(mnr)"DN" [addition]
    *** source: 17451682-Fig-4c
  *** Hif1a-gene promo-reporter[Luc] is increased itpo xJun
    *** cells: CHANG in BMS
    *** source: 17451682-Fig-3a
  *** Hif1a[Ab] boundto(ProTnf-gene)[ChIP] is detectable
    *** cells: CHANG in BMS
    *** source: 17451682-Fig-5d
  *** xHif1a[Ab] copptby[WB] xVhl[Ab] is detectable
    *** cells: HEK293<xHif1a><xVhl> in BMS
    *** source: 12808024-Fig-3a
  *** Hif1a[Ab] prot-exp[WB] is increased itao Phd2 [RNAi]
    *** cells: RAW2647 in BMS
    *** source: 19762779-Fig-3c
  *** Hif1a[Ab] prot-exp[WB] is increased itpo (xTLR4 + xCd4)
    *** cells: THP1 in BMS
    *** source: 18155167-Fig-2
  *** Hif1a[Ab] prot-exp[WB] is unchanged itao Phd1 [RNAi]
    *** cells: RAW2647 in BMS
    *** source: 19762779-Fig-3c
  *** xHif1a[tAb] prot-exp[WB] is increased itpo xAtp6V0c
    *** cells: HEK293 in BMS
    *** inhibited by: xVhl [addition]
    *** source: 17178925(D)
  *** Hif2a[Ab] prot-exp[WB] is unchanged itao Phd1 [RNAi]
    *** cells: RAW2647 in BMS
    *** source: 19762779-Fig-3c
  *** Hif2a[Ab] prot-exp[WB] is unchanged itao Phd2 [RNAi]
    *** cells: RAW2647 in BMS
    *** source: 19762779-Fig-3c
  *** Hifs[Ab] prot-exp[WB] is unchanged itao Tsc2 [KO]
    *** cells: mEFs in BMS
    *** source: 15545625-Fig-1b
  *** Hifs[Ab] prot-exp[WB] is unchanged itao Tsc2 [KO]
    *** cells: mEFs<Tp53~null> in BMS
    *** source: 15545625-Fig-1a
*** Hipk2--
  *** Hipk2[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: U2OS in BMS
    *** source: 11740489-Fig-1
  *** xHipk2[tAb] copptby[WB] Cbp[Ab] is detectable
    *** cells: HEK293<xHipk2> in BMS
    *** unaffected by: xHipk2(1-520)"delC" [substitution]
    *** inhibited by: rHipk2(551-1191)"delN" [substitution]
    *** source: 11740489-Fig-6b
  *** xHipk2[XFP] locatedin(nucleus)[IHC] is detectable
    *** cells: H1299<xHipk2> in BMS
    *** source: 11740489-Fig-1
  *** pHistH1[32P] phos[32P-ATP] is increased by (rCyclinA? + rCdk2)
    *** cells: none
    *** comment: rCyclinA? and rCdk2 were expressed in SF9 cells and purified by chromatograph
    *** source: 9003781-Fig-1c
  *** pHistH1[32P] phos[32P-ATP] is increased by (rCyclinE? + rCdk2)
    *** cells: none
    *** comment: rCyclinE? and rCdk2 were expressed in SF9 cells and purified by chromatograph
    *** source: 9003781-Fig-1c
  *** pHistH1[32P] phos[32P-ATP] is increased by Cdk2[Ab]IP
    *** cells: none
    *** IPfrom: FM3A in BMS
    *** source: 9003781-Fig-3b
  *** pHistH1[32P] phos[32P-ATP] is unchanged by (rCyclinD1 + rCdk4)
    *** cells: none
    *** comment: rCyclinD1 and rCdk4 were expressed in SF9 cells and purified by chromatograph
    *** source: 9003781-Fig-1c
  *** pHistH1[32P] phos[32P-ATP] is unchanged by Cdk4[Ab]IP
    *** cells: none
    *** IPfrom: FM3A in BMS
    *** source: 9003781-Fig-3b
  *** pHistH1[32P] phos[32P-ATP] is unchanged by Cdk6[Ab]IP
    *** cells: none
    *** IPfrom: FM3A in BMS
    *** source: 9003781-Fig-3b
*** HistH2B--
  *** rHistH2B[32P] phos[32P-ATP] is increased by PKA
    *** cells: none
    *** source: 11297520-Fig-1a
  *** rHistH2B[32P] phos[32P-ATP] is increased by pPKA
    *** cells: none
    *** source: 11500364-Fig-3a
  *** rHistH2B[32P] phos[32P-ATP] is increased by rAkt1
    *** cells: none
    *** source: 11500364-Fig-3a
  *** rHistH2B[32P] phos[32P-ATP] is increased by rAkt1(mnr)
    *** cells: none
    *** source: 11297520-Fig-1a
  *** rHistH2B[32P] phos[32P-ATP] is increased by rMsk1
    *** cells: none
    *** source: 11500364-Fig-3a
  *** rHistH2B[32P] phos[32P-ATP] is increased by rRsk1
    *** cells: none
    *** source: 11500364-Fig-3a
  *** rHistH2B[32P] phos[32P-ATP] is increased by rS6k1
    *** cells: none
    *** source: 11500364-Fig-3a
  *** pHistH2B[32P] phos[32P-ATP] is increased by xAkt1(mnr)"CA"[tAb]IP
    *** cells: none
    *** comment: xAkt1-act(IP) is from HEK293 treated with Igf1 (tnr)
    *** source: 9427642-Fig-4d
  *** rHistH2B[32P] phos[32P-ATP] is increased by xMsk1[GST]IP
    *** cells: none
    *** comment: xMsk1[GST]IP is from PMA stimuluated HEK293
    *** source: 11297520-Fig-1a
  *** rHistH2B[32P] phos[32P-ATP] is increased by xRsk1[GST]IP
    *** cells: none
    *** comment: xRsk1[GST]IP is from PMA stimuluated HEK293
    *** source: 11297520-Fig-1a
  *** rHistH2B[32P] phos[32P-ATP] is increased by xS6k1((1-421)/T412E)[tAb]IP
    *** cells: none
    *** comment: xS6k1((1-421)/T412E)IP is from insect cells and activated in vitro with Pdk1
    *** source: 11297520-Fig-1a
  *** pHistH3[3H] methyl[3H-SAM] is increased by rSetd7
    *** cells: none
    *** source: 15525938-Fig-1a
  *** HistH3[Ab] copptby[WB] xTip60[tAb] is detectable
    *** cells: HELAS3<xTip60> in BMS
    *** partially inhibited by: xTip60(Y47A)"CD" [substitution]
    *** source: 19783983-Fig-5a
  *** HistH3[Ab] copptby[WB] xTip60[tAb] is detectable
    *** cells: HELAS3<xTip60> in BMS
    *** unaffected by: xKdm6b [addition]
    *** partially inhibited by: xKdm4a [addition]
    *** inhibited by: xKdm4d [addition]
    *** source: 19783983-Fig-5b
  *** pHistH3[AcAb] acetyl(sitenr)[AcAb] is increased by rPcaf
    *** cells: none
    *** comment: unaffected by previous ubiq by (rE4f1 + rUbe2d2 + rUbe1 + rUbiq)
    *** source: 17110336-Fig-S5b
  *** HistH3[Me3Ab] methyl(K10)[Me3Ab] is detectable
    *** cells: mEFs in BMS
    *** reqs: Suv39h1 and/or Suv39h2 [KO]
    *** source: 19783983-Fig-4b
  *** pHistH3[phosAb] phos(S29)[phosAb] is increased by rMsk1{act}
    *** cells: none
    *** source: 11441012-Fig-6a
  *** HistH3{acetyl}[AcAb] boundto(Cdkn1b-gene)[ChIP] is detectable
    *** cells: HELA in BMS
    *** does not req: Arrb1 [RNAi]
    *** unaffected by: xArrb1 [addition]
    *** unaffected by: xArrb1(Q394L) [addition]
    *** source: 16325578-Fig-3a
  *** HistH3{acetyl}[AcAb] boundto(Cdkn1b-gene)[ChIP] is detectable
    *** cells: HELA in BMS
    *** partially reqs: Arrb1 [RNAi]
    *** enhanced by: xArrb1 [addition]
    *** unaffected by: xArrb1(Q394L) [addition]
    *** source: 16325578-Fig-5a
  *** HistH3{acetyl}[AcAb] boundto(Cdkn1b-gene)[ChIP] is detectable
    *** cells: HELA in BMS
    *** unaffected by: xEp300 [addition]
    *** unaffected by: xEp300(mnr)"DN" [addition]
    *** source: 16325578-Fig-5a
  *** HistH3{acetyl}[AcAb] boundto(Cdkn1b-gene)[ChIP] is unchanged itpo xArrb1
    *** cells: mEFs<Arrb1~null><Arrb2~null> in BMS
    *** unaffected by: xArrb1(Q394L) [substitution]
    *** source: 16325578-Fig-3a
  *** HistH3{acetyl}[AcAb] boundto(Cdkn1b-gene)[ChIP] is unchanged itpo xArrb1
    *** cells: mEFs<Arrb1~null><Arrb2~null> in BMS
    *** unaffected by: xArrb1(Q394L) [substitution]
    *** source: 16325578-Fig-5b
  *** HistH3{acetyl}[AcAb] boundto(Cdkn1b-gene)[ChIP] is unchanged itpo xEp300
    *** cells: mEFs<Arrb1~null><Arrb2~null> in BMS
    *** unaffected by: xEp300(mnr)"DN" [substitution]
    *** source: 16325578-Fig-5b
  *** HistH3{acetyl}[AcAb] boundto(Fos-gene)[ChIP] is detectable
    *** cells: HELA in BMS
    *** does not req: Arrb1 [RNAi]
    *** unaffected by: xArrb1 [addition]
    *** unaffected by: xArrb1(Q394L) [addition]
    *** source: 16325578-Fig-3a
  *** HistH3{acetyl}[AcAb] boundto(Fos-gene)[ChIP] is unchanged itpo xArrb1
    *** cells: mEFs<Arrb1~null><Arrb2~null> in BMS
    *** unaffected by: xArrb1(Q394L) [substitution]
    *** source: 16325578-Fig-3a
  *** HistH3{acetyl}[AcAb] boundto(Jun-gene)[ChIP] is detectable
    *** cells: HELA in BMS
    *** does not req: Arrb1 [RNAi]
    *** unaffected by: xArrb1 [addition]
    *** unaffected by: xArrb1(Q394L) [addition]
    *** source: 16325578-Fig-3a
  *** HistH3{acetyl}[AcAb] boundto(Jun-gene)[ChIP] is detectable
    *** cells: HELA in BMS
    *** unaffected by: xEp300 [addition]
    *** unaffected by: xEp300(mnr)"DN" [addition]
    *** source: 16325578-Fig-5a
  *** HistH3{acetyl}[AcAb] boundto(Jun-gene)[ChIP] is unchanged itpo xArrb1
    *** cells: mEFs<Arrb1~null><Arrb2~null> in BMS
    *** unaffected by: xArrb1(Q394L) [substitution]
    *** source: 16325578-Fig-3a
  *** HistH3{acetyl}[AcAb] boundto(Jun-gene)[ChIP] is unchanged itpo xArrb1
    *** cells: mEFs<Arrb1~null><Arrb2~null> in BMS
    *** unaffected by: xArrb1(Q394L) [substitution]
    *** source: 16325578-Fig-5b
  *** HistH3{acetyl}[AcAb] boundto(Jun-gene)[ChIP] is unchanged itpo xEp300
    *** cells: mEFs<Arrb1~null><Arrb2~null> in BMS
    *** unaffected by: xEp300(mnr)"DN" [substitution]
    *** source: 16325578-Fig-5b
  *** HistH3{phos(S11)}[phosAb] boundto(CcL2-gene)[ChIP] is detectable
    *** cells: mEFs in BMS
    *** partially reqs: Jun [KO]
    *** source: 18443042-Fig-8b
  *** HistH4{acetyl(K6/K9/K13/K17)}[AcAb] boundto(CcL2-gene)[ChIP] is increased itao Jun [KO]
    *** cells: mEFs in BMS
    *** source: 18443042-Fig-8b
  *** HistH4{acetyl}[AcAb] boundto(Cdkn1b-gene)[ChIP] is detectable
    *** cells: HELA in BMS
    *** enhanced by: xEp300 [addition]
    *** inhibited by: xEp300(mnr)"DN" [addition]
    *** source: 16325578-Fig-5a
  *** HistH4{acetyl}[AcAb] boundto(Cdkn1b-gene)[ChIP] is detectable
    *** cells: HELA in BMS
    *** partially reqs: Arrb1 [RNAi]
    *** enhanced by: xArrb1 [addition]
    *** unaffected by: xArrb1(Q394L) [addition]
    *** source: 16325578-Fig-3a
  *** HistH4{acetyl}[AcAb] boundto(Cdkn1b-gene)[ChIP] is detectable
    *** cells: HELA in BMS
    *** partially reqs: Arrb1 [RNAi]
    *** enhanced by: xArrb1 [addition]
    *** unaffected by: xArrb1(Q394L) [addition]
    *** source: 16325578-Fig-5a
  *** HistH4{acetyl}[AcAb] boundto(Cdkn1b-gene)[ChIP] is increased itpo xArrb1
    *** cells: mEFs<Arrb1~null><Arrb2~null> in BMS
    *** inhibited by: xArrb1(Q394L) [substitution]
    *** source: 16325578-Fig-3a
  *** HistH4{acetyl}[AcAb] boundto(Cdkn1b-gene)[ChIP] is increased itpo xArrb1
    *** cells: mEFs<Arrb1~null><Arrb2~null> in BMS
    *** inhibited by: xArrb1(Q394L) [substitution]
    *** source: 16325578-Fig-5b
  *** HistH4{acetyl}[AcAb] boundto(Cdkn1b-gene)[ChIP] is increased itpo xEp300
    *** cells: mEFs<Arrb1~null><Arrb2~null> in BMS
    *** inhibited by: xEp300(mnr)"DN" [substitution]
    *** source: 16325578-Fig-5b
  *** HistH4{acetyl}[AcAb] boundto(Fos-gene)[ChIP] is detectable
    *** cells: HELA in BMS
    *** partially reqs: Arrb1 [RNAi]
    *** enhanced by: xArrb1 [addition]
    *** unaffected by: xArrb1(Q394L) [addition]
    *** source: 16325578-Fig-3a
  *** HistH4{acetyl}[AcAb] boundto(Fos-gene)[ChIP] is increased itpo xArrb1
    *** cells: mEFs<Arrb1~null><Arrb2~null> in BMS
    *** inhibited by: xArrb1(Q394L) [substitution]
    *** source: 16325578-Fig-3a
  *** HistH4{acetyl}[AcAb] boundto(Jun-gene)[ChIP] is detectable
    *** cells: HELA in BMS
    *** does not req: Arrb1 [RNAi]
    *** unaffected by: xArrb1 [addition]
    *** unaffected by: xArrb1(Q394L) [addition]
    *** source: 16325578-Fig-3a
  *** HistH4{acetyl}[AcAb] boundto(Jun-gene)[ChIP] is detectable
    *** cells: HELA in BMS
    *** unaffected by: xEp300 [addition]
    *** unaffected by: xEp300(mnr)"DN" [addition]
    *** source: 16325578-Fig-5a
  *** HistH4{acetyl}[AcAb] boundto(Jun-gene)[ChIP] is unchanged itpo xArrb1
    *** cells: mEFs<Arrb1~null><Arrb2~null> in BMS
    *** unaffected by: xArrb1(Q394L) [substitution]
    *** source: 16325578-Fig-3a
  *** HistH4{acetyl}[AcAb] boundto(Jun-gene)[ChIP] is unchanged itpo xArrb1
    *** cells: mEFs<Arrb1~null><Arrb2~null> in BMS
    *** unaffected by: xArrb1(Q394L) [substitution]
    *** source: 16325578-Fig-5b
  *** HistH4{acetyl}[AcAb] boundto(Jun-gene)[ChIP] is unchanged itpo xEp300
    *** cells: mEFs<Arrb1~null><Arrb2~null> in BMS
    *** unaffected by: xEp300(mnr)"DN" [substitution]
    *** source: 16325578-Fig-5b
  *** xHivep3[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xFoxp3
    *** cells: HEK293T in BMS
    *** source: 15790681-Fig-4d
  *** Hlx-gene mRNA[RTPCR] is detectable
    *** cells: hNKCs in BMS
    *** comment: Cd56-pos cells express more than Cd56-neg cells [FACS-sort]
    *** source: 17110450-Fig-1c
  *** Hlx[Ab] prot-exp[WB] is detectable
    *** cells: hNKCs in BMS
    *** comment: Cd56-pos cells express more than Cd56-neg cells [FACS-sort]
    *** source: 17110450-Fig-1c
  *** Hmgb1[Ab] snaggedby[WB] Poly-dAdT-dTdA[biotin] is detectable
    *** cells: mEFs in BMS "transfected with Poly-dAdT-dTdA for 4 hr"
    *** source: 19890330-Fig-S1a
  *** Hmgb2[Ab] snaggedby[WB] Poly-dAdT-dTdA[biotin] is detectable
    *** cells: mEFs in BMS "transfected with Poly-dAdT-dTdA for 4 hr"
    *** source: 19890330-Fig-S1a
  *** Hmgb3[Ab] snaggedby[WB] Poly-dAdT-dTdA[biotin] is detectable
    *** cells: mEFs in BMS "transfected with Poly-dAdT-dTdA for 4 hr"
    *** source: 19890330-Fig-S1a
  *** pHMRSK[biotin] boundby[SPR] rRsk3(1-373)[GST] is detectable
    *** cells: none
    *** inhibited by: rRsk3(1-373/R119A) [substitution] 
    *** source: 12374740-Fig-7
  *** Hpk1[Ab] snaggedby[WB] rCrk[GST] is detectable
    *** cells: JURKAT<Pten~null> in BMS
    *** source: 9891069-Fig-1a
  *** Hpk1[Ab] snaggedby[WB] rCrkL[GST] is detectable
    *** cells: JURKAT<Pten~null> in BMS
    *** source: 9891069-Fig-1a
  *** Hpk1[Ab] snaggedby[WB] rNck1[GST] is detectable
    *** cells: JURKAT<Pten~null> in BMS
    *** source: 9891069-Fig-1a
  *** Hpk1[Ab] snaggedby[WB] rRac1[GST] is undetectable
    *** cells: JURKAT<Pten~null> in BMS
    *** source: 9891069-Fig-1a
  *** xHpk1[tAb]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: HELA in BMS
    *** unaffected by: xMlk3(K144R)"KD" [addition]
    *** partially inhibited by: xMlk3(S281A) [substitution]
    *** source: 11053428-Fig-7
  *** xHpk1[tAb]IP IVKA(Crk)[32P-ATP] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xHpk1(K64M) [substitution]
    *** source: 9891069-Fig-8a
  *** xHpk1[tAb]IP IVKA(CrkL)[32P-ATP] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xHpk1(K64M) [substitution]
    *** source: 9891069-Fig-8a
  *** xHpk1[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xCrk
    *** cells: HEK293T in BMS
    *** source: 9891069-Fig-5a
  *** xHpk1[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xCrkL
    *** cells: HEK293T in BMS
    *** source: 9891069-Fig-5a
  *** rHras GDP-dissociation[3H-GDP] is increased by rVav1{Yphos}
    *** cells: none
    *** inhibited by: rVav1 [substitution]
    *** comment: rVav1 was phosphorylated by rLck
    *** source: 8289830-Fig-2
  *** rHras GDP-dissociation[3H-GDP] is unchanged by rPlce1
    *** cells: none
    *** source: 11395506-Fig-3
  *** rHras GDP-dissociation[3H-GDP] is unchanged by rRalGds
    *** cells: none
    *** source: 8094051-Fig-5
  *** rHras GDP-dissociation[3H-GDP] is unchanged by rRap1Gds1
    *** cells: none
    *** source: 11948427-Fig-1d
  *** rHras GDP-dissociation[3H-GDP] is unchanged by rRapGef1
    *** cells: none
    *** source: 8524240-Fig-2a
  *** rHras GDP-dissociation[Mant-GDP] is unchanged by rRasGef1a
    *** cells: none
    *** source: 19645719-Fig-1c
  *** rHras GDP-dissociation[Mant-GDP] is unchanged by rRasGef1b
    *** cells: none
    *** source: 19645719-Fig-1c
  *** rHras GTP-hydrolysis[32P-GTP] is unchanged by rGna12{GTPgS}
    *** cells: none
    *** source: 9796816-Fig-4c
  *** rHras GTP-hydrolysis[32P-GTP] is unchanged by rRasa3
    *** cells: none
    *** source: 10777492-Fig-3
  *** rHras GTP-hydrolysis[32P-GTP] is unchanged by rRasa3(mnr)"Gap-Related-Domain"
    *** cells: none
    *** source: 8530488-Fig-5b
  *** rHras GTP-hydrolysis[32P-GTP] is unchanged by rSipa1
    *** cells: none
    *** source: 9346962-Fig-3a
  *** xHras(G12V)"CA"[tAb]IP IVKA(Mek1,Erk2,MBP)[32P-ATP] is increased itpo (xMras(H81L)"CA" + xShoc2)
    *** cells: HEK293T<xRaf1> in BMS
    *** partially reqs: xShoc2 [omission]
    *** reqs: xMras(H81L)"CA" [omission]
    *** source: 16630891-Fig-6c
  *** xHras(Q61L)[Ab] copptby[WB] xRin1(294-783)"Cterm"[tAb] is detectable
    *** cells: NIH3T3<xRin1(294-783)"Cterm"><xHras(Q61L)> in BMS
    *** source: 9144171-Fig-2b
  *** xHras(S17N)[Ab] copptby[WB] xRap1Gds1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xHras(S17N/E37G)[GST] [substitution]
    *** enhanced by: xHras(G15A)[GST] [substitution]
    *** source: 11948427-Fig-2b,2c
  *** rHras(S17N)[GST] boundby[WB] rRap1Gds1[GST] is detectable
    *** cells: none
    *** unaffected by: rRhoa [addition]
    *** source: 11948427-Fig-3c
  *** xHras[Ab] copptby[WB] xRig1[tAb] is detectable
    *** cells: HTTA in BMS
    *** inhibited by: xRig1(del(Cterm)) [substitution]
    *** source: 16005186-Fig-4b
  *** Hras[Ab] GTP-association[BDPD] is decreased itao Arms [RNAi]
    *** cells: PC12 in BMLS
    *** source: 15167895-Fig-7a
  *** Hras[Ab] GTP-association[BDPD] is detectable
    *** cells: mEFs in BMLS
    *** unaffected by: Tsc2 [KO]
    *** source: 12820960-Fig-1a
  *** Hras[Ab] GTP-association[BDPD] is increased itpo (xTnk2 + xCdc42(G12V)"CA")
    *** cells: HEK293<xRasGrf1> in BMLS
    *** source: 10882715-Fig-6
  *** Hras[Ab] GTP-association[BDPD] is increased itpo xRanbp9
    *** cells: HELA in BMLS
    *** unaffected by: Genistein [pretreatment]
    *** source: 12147692-Fig-5a
  *** xHras[Ab] GTP-association[BDPD] is increased itpo xRasa1((1-445)/D157A)"Casp-resistant"
    *** cells: HELA in BMS
    *** unaffected by: xRasa1(456-1047)"Cterm" [addition]     
    *** source: 11847220-Fig-1b
  *** Hras[Ab] GTP-association[BDPD] is increased itpo xRasGrp3
    *** cells: RAT1A in BMS
    *** source: 10835426-Fig-7d
  *** Hras[Ab] GTP-association[BDPD] is increased itpo xRasGrp4
    *** cells: 32D in BMLS "IL3 deprived"
    *** enhanced by: PMA (30 min) [stim]
    *** source: 11880369-Fig-3c
  *** Hras[Ab] GTP-association[BDPD] is increased itpo xRasGrp4
    *** cells: RAT1 in BMLS
    *** source: 11880369-Fig-2b
  *** xHras[Ab] GTP-association[BDPD] is increased itpo xSrc(mnr)"vSrc"
    *** cells: COS7<xHras> in BMLS
    *** source: 10330169-Fig-3c
  *** Hras[Ab] GTP-association[BDPD] is increased itpo xTnk2(L543F)"CA"
    *** cells: HEK293<xRasGrf1> in BMLS
    *** source: 10882715-Fig-6
  *** Hras[Ab] GTP-association[BDPD] is unchanged itpo xBraf
    *** cells: COS7 in BMS
    *** unaffected by: xBraf(G466E) [substitution]
    *** unaffected by: xBraf(G466V) [substitution]
    *** unaffected by: xBraf(G596R) [substitution]
    *** source: 16364920-Fig-2a
  *** Hras[Ab] GTP-association[BDPD] is unchanged itpo xPdpk1(mnr)"CA"
    *** cells: HEK293 in BMS
    *** source: 11889038-Fig-2b
  *** xHras[Ab] GTP-association[BDPD] is unchanged itpo xPik3c?(mnr)"CAAX" 
    *** cells: COS7<xHras> in BMLS
    *** source: 10330169-Fig-3c
  *** xHras[Ab] GTP-association[BDPD] is unchanged itpo xRasa1(456-1047)"Cterm"
    *** cells: HELA in BMS
    *** source: 11847220-Fig-1b
  *** Hras[Ab] GTP-association[BDPD] is unchanged itpo xRasGrp2
    *** cells: RAT1A in BMS
    *** source: 10835426-Fig-7d
  *** Hras[Ab] prot-stability[CHX-WB] is decreased itpo xRig1
    *** cells: HTTA in BMS
    *** source: 16005186-Fig-1d
  *** xHras[GST]IP GTP-association[TLC] is unchanged itpo xRapGef1
    *** cells: COS7 in BMS
    *** source: 8524240-Fig-5
  *** xHras[GST]IP GTP-association[TLC] is unchanged itpo xRapGef3
    *** cells: HEK293T in BMS
    *** source: 9856955-Fig-2a
  *** xHras[GST]IP GTP-association[TLC] is unchanged itpo xRapGef4
    *** cells: HEK293T in BMS
    *** source: 9856955-Fig-2b
  *** xHras[GST]IP GTP-association[TLC] is unchanged itpo xRasGrp2
    *** cells: HEK293T in BMS
    *** source: 9789079-Fig-2a
  *** xHras[tAb] GTP-association[BDPD] is detectable
    *** cells: CHO<xInsR> in BMLS
    *** unaffected by: xDok1 [addition]
    *** inhibited by: rDok1(Y362F/Y398F) [addition]
    *** source: 11551902-Fig-6a
  *** xHras[tAb] GTP-association[BDPD] is increased itpo xPlce1
    *** cells: TSA201 in BMS
    *** enhanced by: xPlce1(H1144L)"CIA" [substitution]
    *** source: 11022047-Fig-8a
  *** xHras[tAb] GTP-association[BDPD] is increased itpo xRasGrp3
    *** cells: HEK293T in BMLS
    *** source: 10934204-Fig-3b
  *** xHras[tAb] GTP-association[BDPD] is increased itpo xRasGrp3
    *** cells: RAT1 in BMLS
    *** source: 11880369-Fig-2c
  *** xHras[tAb] GTP-association[BDPD] is increased itpo xRasGrp4
    *** cells: RAT1 in BMLS
    *** source: 11880369-Fig-2c
  *** xHras[tAb] GTP-association[BDPD] is unchanged itpo xRalGps1
    *** cells: COS7 in BMS
    *** source: 10889189-Fig-4c
  *** xHras[tAb] GTP-association[BDPD] is unchanged itpo xRap1Gds1
    *** cells: HEK293T in BMLS
    *** source: 10934204-Fig-3b
  *** xHras[tAb] GTP-association[BDPD] is unchanged itpo xRapGef1
    *** cells: HEK293T in BMLS
    *** source: 10934204-Fig-3b
  *** xHras[tAb] GTP-association[BDPD] is unchanged itpo xRapGef2
    *** cells: COS7 in BMS
    *** source: 10608883-Fig-3b
  *** xHras[tAb] GTP-association[BDPD] is unchanged itpo xRapGef2
    *** cells: HEK293T in BMLS
    *** source: 10934204-Fig-3b
  *** xHras[tAb] GTP-association[BDPD] is unchanged itpo xRapGef5
    *** cells: HEK293T in BMLS
    *** source: 10934204-Fig-3b
  *** xHras[tAb] GTP-association[BDPD] is unchanged itpo xRapGef6
    *** cells: COS7 in BMS
    *** source: 11524421-Fig-3c
  *** xHras[tAb] GTP-association[BDPD] is unchanged itpo xRasGrp2
    *** cells: RAT1 in BMLS
    *** source: 11880369-Fig-2c
  *** xHras[tAb] GTP-association[BDPD] is unchanged itpo xRgl2
    *** cells: HEK293T in BMLS
    *** source: 10934204-Fig-3b
  *** xHras[tAb] GTP-association[BDPD] is unchanged itpo xRgl2
    *** cells: RAT1 in BMLS
    *** source: 11880369-Fig-2c
  *** xHras[tAb] GTP-association[BDPD] is unchanged itpo xSh2d3c
    *** cells: HEK293T in BMS
    *** source: 12432078-Fig-2b
  *** xHras[tAb] GTP-association[TLC] is increased itpo xSrc(mnr)"vSrc"
    *** cells: COS7<xHras> in BMLS
    *** source: 10330169-Fig-3b
  *** xHras[tAb] GTP-association[TLC] is unchanged itpo xPik3c?(mnr)"CAAX" 
    *** cells: COS7<xHras> in BMLS
    *** source: 10330169-Fig-3b
  *** xHras[tAb]IP GTP-association[TLC] is increased itpo xRasGrp3
    *** cells: HEK293T in BMS
    *** source: 10835426-Fig-3a
  *** xHras[tAb]IP GTP-association[TLC] is unchanged itpo xBcar3
    *** cells: HEK293 in BMS
    *** source: 10896938-Fig-1c
  *** xHras[tAb]IP GTP-association[TLC] is unchanged itpo xRapGef6
    *** cells: COS7 in BMS
    *** source: 11524421-Fig-3d
  *** xHras[tAb]IP GTP-association[TLC] is unchanged itpo xRasGrp2
    *** cells: COS in BMS
    *** source: 10918068-Fig-4a
  *** xHras[tAb]IP GTP-association[TLC] is unchanged itpo xRasGrp2
    *** cells: HEK293T in BMS
    *** source: 10835426-Fig-3a
  *** xHras[tAb]IP GTP-association[TLC] is unchanged itpo xVav1(67-845)
    *** cells: COS7 in BMS
    *** comment: results are reported as bound labelled GDP
    *** source: 8990121-Fig-3a
  *** rHras{GDP} GDP-dissociation[3H-GDP] is increased by rRasGrf1
    *** cells: none
    *** source: 12147692-Fig-5b
  *** rHras{GDP} GDP-dissociation[3H-GDP] is increased by xRanbp9[tAb]IP
    *** cells: none
    *** IPfrom: HEK293 in BMLS
    *** source: 12147692-Fig-5b
  *** rHras{GDP} GDP-dissociation[3H-GDP] is unchanged by rRanbp9
    *** cells: none
    *** source: 12147692-Fig-5b
  *** rHras{GDP} GTP-association[35S-GTPgS] is unchanged by rVav1{Yphos}
    *** cells: none
    *** comment: rVav1 was phosphorylated by rLck
    *** unaffected by: rVav1 [substitution]
    *** source: 8990121-Fig-2a
  *** HRE-reporter[Luc] is increased itao Phd2 [RNAi]
    *** cells: RAW2647 in BMS
    *** source: 19762779-Fig-3d
  *** HRE-reporter[Luc] is increased itpo xHif1a(mnr)"stabilized"
    *** cells: RAW2647 in BMS
    *** source: 19762779-Fig-3e
  *** HRE-reporter[Luc] is unchanged itao Phd1 [RNAi]
    *** cells: RAW2647 in BMS
    *** source: 19762779-Fig-3d
  *** rHsp70[Ab] boundby[WB] rRaf1[GST] is undetectable
    *** cells: none
    *** source: 11231577-Fig-2a
  *** Hsp70[Ab] copptby[WB] Bag1[Ab] is detectable
    *** cells: PC12 in BMS
    *** source: 16116448-Fig-7a
  *** Hsp70[Ab] copptby[WB] Braf[Ab] is detectable
    *** cells: PC12 in BMS
    *** source: 16116448-Fig-7a
  *** Hsp70[Ab] copptby[WB] xRaf1[tAb] is detectable
    *** cells: COS7 in BMLS
    *** unaffected by: Egf (30 min) [stim]
    *** source: 16093354-Fig-3c
  *** Hsp70[MS] copptby[WB] xKsr1[tAb] is detectable
    *** cells: COS in BMS
    *** source: 12932319-Fig-1a
  *** Hsp70[MS] copptby[WB] xRaf1[tAb] is detectable
    *** cells: COS7 in BMLS
    *** unaffected by: Egf (30 min) [stim]
    *** source: 16093354-Fig-3a
  *** Hsp90[Ab] copptby[WB] Ikk1[Ab] is detectable
    *** cells: HELA in BMS
    *** unaffected by: Tnf (tnr) [stim]
    *** source: 11864612-Fig-3a,4a
  *** Hsp90[Ab] copptby[WB] Ksr1[Ab] is detectable
    *** cells: PC12 in BMS "differentiated with Ngf for 5 days"
    *** source: 10409742-Fig-2g
  *** Hsp90[Ab] copptby[WB] Mlk3[Ab] is detectable
    *** cells: MCF7 in BMS
    *** source: 15001580(D)
  *** Hsp90[Ab] copptby[WB] Nemo[Ab] is detectable
    *** cells: HELA in BMS
    *** inhibited by: Geldanamycin [addition]
    *** source: 11864612-Fig-5a
  *** Hsp90[Ab] copptby[WB] Nemo[Ab] is detectable
    *** cells: HELA in BMS
    *** unaffected by: Tnf (tnr) [stim]
    *** source: 11864612-Fig-4a
  *** Hsp90[Ab] copptby[WB] xBraf[tAb] is detectable
    *** cells: COS1 in BMS
    *** unaffected by: xBraf(T598A) [substitution]
    *** unaffected by: xBraf(S601A) [substitution]
    *** unaffected by: xBraf(T598A/S601A) [substitution]
    *** source: 11032810-Fig-3
  *** Hsp90[Ab] copptby[WB] xKsr1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 10409742-Fig-1f
  *** Hsp90[Ab] copptby[WB] xMlk3[Ab] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: xCdc42(G12V)"CA" [addition]
    *** unaffected by: xMlk3(K144A)"KD" [substitution]
    *** source: 15001580(D)
  *** Hsp90[Ab] copptby[WB] xMlk3[tAb] is detectable
    *** cells: MCF7 in BMS "containing AP21967 to induce xMlk3"
    *** source: 15001580(D)
  *** Hsp90[Ab] copptby[WB] xRaf1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** enhanced by: xRaf1(T491A/S494A) [substitution]
    *** enhanced by: xRaf1(T491E/S494D) [substitution]
    *** enhanced by: xRaf1(T491E/S494D/S338D/S341D) [substitution]
    *** source: 11447113-Fig-4
  *** Hsp90[MS] copptby[WB] xRaf1[tAb] is detectable
    *** cells: COS7 in BMLS
    *** unaffected by: Egf (30 min) [stim]
    *** source: 16093354-Fig-3a
  *** Hsp90aa1[MS] copptby[WB] xKsr1[tAb] is detectable
    *** cells: COS in BMS
    *** source: 12932319-Fig-1a
  *** Hsp90aa1[MS] copptby[WB] xMlk3[tAb] is detectable
    *** cells: MCF7 in BMS "containing AP21967 to induce xMlk3"
    *** source: 15001580(D)
  *** Hsp90ab1[MS] copptby[WB] xKsr1[tAb] is detectable
    *** cells: COS in BMS
    *** source: 12932319-Fig-1a
  *** xHspa1a[Ab] copptby[WB] xBag1[tAb] is detectable
    *** cells: OT23 in BMS
    *** inhibited by: xBag1(C204A)"Hsp70-binding-mut" [substitution]
    *** inhibited by: xBag1(E208A)"Hsp70-binding-mut" [substitution]
    *** source: 11231577-Fig-4b
  *** rHspa1a[tAb] boundby[WB] rBag1[GST] is detectable
    *** cells: none
    *** inhibited by: rRaf1 [addition]
    *** source: 11231577-Fig-1a
  *** Hspa5[MS] copptby[WB] xMras(H81L)"CA"[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 16630891-Fig-1a
  *** Hspa8[Ab] copptby[WB] xRaf1[tAb] is detectable
    *** cells: COS7 in BMLS
    *** unaffected by: Egf (30 min) [stim]
    *** source: 16093354-Fig-3c
  *** Hspa8[MS] copptby[WB] xMras(H81L)"CA"[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 16630891-Fig-1a
  *** Hspa8[MS] copptby[WB] xRaf1[tAb] is detectable
    *** cells: COS7 in BMLS
    *** unaffected by: Egf (30 min) [stim]
    *** source: 16093354-Fig-3a
  *** rHspb1[GST] phos[32P-ATP] is unchanged by xMsk1[Ab]IP
    *** cells: none
    *** IPfrom: HEK293<xMsk1> in BMS "treated with PMA for 15 min"
    *** source: 9687510-Fig-8b
  *** rHspb1[GST] phos[32P-ATP] is unchanged by xRsk1[Ab]IP
    *** cells: none
    *** IPfrom: HEK293<xRsk1> in BMS "treated with PMA for 15 min"
    *** source: 9687510-Fig-8b
  *** rHspb1[GST] phos[32P-ATP] is unchanged by xRsk3[Ab]IP
    *** cells: none
    *** IPfrom: HEK293<xRsk3> in BMS "treated with PMA for 15 min"
    *** source: 9687510-Fig-8b
  *** Hspb1[phosAb] phos(S78)[phosAb] is detectable
    *** cells: HEPG2 in BMLS "plated on collagen"
    *** partially inhibited by: Gefitinib [cotreatment]
    *** partially inhibited by: PD325901 [cotreatment]
    *** partially inhibited by: BMS345541 [cotreatment]
    *** partially inhibited by: PHA818637 [cotreatment]
    *** partially inhibited by: ZSTK474 [cotreatment]
    *** source: 19953085-Fig-S1
  *** Hspb1[phosAb] phos(S82)[phosAb] is increased itpo xRin1(Q78L)
    *** cells: PC6 in BMLS
    *** enhanced by: xBraf [addition]
    *** source: 16157584-Fig-6f
  *** Hspb1[phosAb] phos(S82)[phosAb] is increased itpo xRin1(Q78L)
    *** cells: PC6 in BMLS
    *** enhanced by: xBraf [addition]
    *** source: 16157584-Fig-6g
  *** Hspb1[phosAb] phos(S82)[phosAb] is increased itpo xRin1(Q78L)
    *** cells: PC6<xBraf> in BMLS
    *** inhibited by: SB203580 [pretreatment]
    *** source: 16157584-Fig-6f
  *** Hspb1[phosAb] phos(S82)[phosAb] is increased itpo xRin1(Q78L)
    *** cells: PC6<xBraf> in BMLS
    *** unaffected by: PD98059 [pretreatment]
    *** source: 16157584-Fig-6g
  *** rHuwe1(1-1014)[35S] boundby[WB] rMdm2[GST] is undetectable
    *** cells: none
    *** source: 15989956-Fig-6a
  *** rHuwe1(1015-4374)[35S] boundby[WB] rMdm2[GST] is undetectable
    *** cells: none
    *** source: 15989956-Fig-6a
  *** Huwe1[Ab] prot-exp[WB] is unchanged itao Cop1 [RNAi]
    *** cells: U2OS in BMS
    *** source: 15989956-Fig-8a
  *** Huwe1[Ab] prot-exp[WB] is unchanged itao Mdm2 [RNAi]
    *** cells: U2OS in BMS
    *** source: 15989956-Fig-8a
  *** Huwe1[Ab] prot-exp[WB] is unchanged itao Mdm2 [RNAi]
    *** cells: U2OS in BMS
    *** source: 15989956-Fig-S4a
  *** Huwe1[Ab] prot-exp[WB] is unchanged itao Pirh2 [RNAi]
    *** cells: U2OS in BMS
    *** source: 15989956-Fig-8a
  *** Id1-gene mRNA[RTPCR] is detectable
    *** cells: HACAT in BMS
    *** partially reqs: Smad2 [RNAi]
    *** source: 18955504-Fig-7a
  *** Id1-gene mRNA[RTPCR] is detectable
    *** cells: HACAT in BMS
    *** partially reqs: Smad3 [RNAi]
    *** source: 18955504-Fig-7a
  *** rId1[35S] boundby[WB] rElk1(1-205)[GST] is detectable
    *** cells: none
    *** source: 10022839-Fig-2b
  *** rId1[35S] boundby[WB] rElk4(1-298)[GST] is undetectable
    *** cells: none
    *** source: 10022839-Fig-2c
  *** rId1[35S] boundby[WB] rMyod1[GST] is detectable
    *** cells: none
    *** source: 10022839-Fig-2b
  *** rId1[35S] boundby[WB] rMyod1[GST] is detectable
    *** cells: none
    *** source: 10022839-Fig-2c
  *** rId2[35S] boundby[WB] rElk1(1-205)[GST] is detectable
    *** cells: none
    *** source: 10022839-Fig-2b
  *** rId2[35S] boundby[WB] rElk4(1-298)[GST] is detectable
    *** cells: none
    *** source: 10022839-Fig-2c
  *** rId2[35S] boundby[WB] rMyod1[GST] is detectable
    *** cells: none
    *** source: 10022839-Fig-2b
  *** rId2[35S] boundby[WB] rMyod1[GST] is detectable
    *** cells: none
    *** source: 10022839-Fig-2c
  *** rId3[35S] boundby[WB] rElk1(1-205)[GST] is detectable
    *** cells: none
    *** source: 10022839-Fig-2b
  *** rId3[35S] boundby[WB] rElk4(1-298)[GST] is detectable
    *** cells: none
    *** source: 10022839-Fig-2c
  *** rId3[35S] boundby[WB] rMyod1[GST] is detectable
    *** cells: none
    *** source: 10022839-Fig-2b
  *** rId3[35S] boundby[WB] rMyod1[GST] is detectable
    *** cells: none
    *** source: 10022839-Fig-2c
  *** Ifi6-gene mRNA[RTPCR] is detectable
    *** cells: mEFs in BMS
    *** reqs: Cbp [KO]
    *** source: 17923090-Fig-7e
  *** Ifit2-gene mRNA[RTPCR] is detectable
    *** cells: mEFs in BMS
    *** reqs: Cbp [KO]
    *** source: 17923090-Fig-7e
  *** Ifit2-gene mRNA[RTPCR] is increased itpo xIrf9
    *** cells: U2A<Irf9~null> in BMS
    *** inhibited by: xIrf9(K47R) [substitution]
    *** inhibited by: xIrf9(K81R) [substitution]
    *** source: 17923090-Fig-7f
  *** Ifit2-gene promo-reporter[Luc] is increased itpo (xIrf9 + xStat2)
    *** cells: HEK293T in BMS
    *** unaffected by: xStat1 [addition]
    *** enhanced by: xCbp [addition]
    *** source: 17923090-Fig-7a
  *** Ifit2-gene promo-reporter[Luc] is increased itpo (xStat1 + xStat2 + xIrf9)
    *** cells: HEK293T in BMS
    *** partially reqs: Cbp [RNAi]
    *** source: 17923090-Fig-S5a
  *** Ifit2-gene promo-reporter[Luc] is increased itpo (xStat1 + xStat2)
    *** cells: HEK293T in BMS
    *** reqs: both [omission]
    *** unaffected by: xCbp [addition]
    *** source: 17923090-Fig-7a
  *** Ifit2-gene promo-reporter[Luc] is increased itpo xCbp
    *** cells: HEK293T<xIrf3><xStat2> in BMS
    *** enhanced by: xStat1 [addition]
    *** source: 17923090-Fig-7a
  *** Ifit2-gene promo-reporter[Luc] is increased itpo xIfnaR2
    *** cells: U5A<IfnaR2~null> in BMS
    *** inhibited by: xHdac6 [addition]
    *** source: 17923090-Fig-7b
  *** Ifit2-gene promo-reporter[Luc] is increased itpo xIfnaR2
    *** cells: U5A<IfnaR2~null> in BMS
    *** inhibited by: xIfnaR2(K399R) [substitution]
    *** inhibited by: xIfnaR2(S364A) [substitution]
    *** inhibited by: xIfnaR2(S384A) [substitution]
    *** inhibited by: xIfnaR2(K399R/S400A) [substitution]
    *** partially inhibited by: xIfnaR2(S400A) [substitution]
    *** source: 17923090-Fig-7b
  *** Ifit2-gene promo-reporter[Luc] is increased itpo xIrf9
    *** cells: HEK293T in BMS
    *** unaffected by: xStat1 [addition]
    *** enhanced by: xStat2 [addition]
    *** unaffected by: xCbp [addition]
    *** source: 17923090-Fig-7a
  *** Ifit2-gene promo-reporter[Luc] is increased itpo xIrf9
    *** cells: U2A<Irf9~null> in BMS
    *** unaffected by: xIrf9(K43R) [substitution]
    *** enhanced by: xIrf9(K47R) [substitution]
    *** unaffected by: xIrf9(K66R) [substitution]
    *** unaffected by: xIrf9(K68R) [substitution]
    *** inhibited by: xIrf9(K81R) [substitution]
    *** unaffected by: xIrf9(K90R) [substitution]
    *** unaffected by: xIrf9(K110R) [substitution]
    *** enhanced by: xIrf9(K128R) [substitution]
    *** unaffected by: xIrf9(K132R) [substitution]
    *** source: 17923090-Fig-7b
  *** Ifit2-gene promo-reporter[Luc] is increased itpo xStat2
    *** cells: U6A<Stat2~null> in BMS
    *** unaffected by: xStat2(K182R) [substitution]
    *** unaffected by: xStat2(K184R) [substitution]
    *** unaffected by: xStat2(K194R) [substitution]
    *** unaffected by: xStat2(K197R) [substitution]
    *** unaffected by: xStat2(K384R) [substitution]
    *** inhibited by: xStat2(K390R) [substitution]
    *** unaffected by: xStat2(K415R) [substitution]
    *** unaffected by: xStat2(K419R) [substitution]
    *** unaffected by: xStat2(K592R) [substitution]
    *** source: 17923090-Fig-7b
  *** Ifitm1-gene mRNA[RTPCR] is detectable
    *** cells: mEFs in BMS
    *** reqs: Cbp [KO]
    *** source: 17923090-Fig-7e
  *** Ifna-gene mRNA[Northern] is increased irt HSV-infection (times)
    *** cells: mEFs in BMS
    *** times: 0 6 12 18+ hr
    *** reqs: Irf3 and/or Irf9 [KO]
    *** source: 11070172-Fig-4c
  *** Ifna-gene mRNA[Northern] is increased irt NDV-infection (8 hr)
    *** cells: mEFs<Irf3~null><xIrf3><Irf9~null><xIrf7> in BMS
    *** does not req: xIrf3 [omission]
    *** reqs: xIrf7 [omission]
    *** source: 11070172-Fig-5a
  *** Ifna-gene mRNA[Northern] is increased irt NDV-infection (8 hr)
    *** cells: mSpCs in BMS
    *** reqs: Irf3 and/or Irf9 [KO]
    *** source: 11070172-Fig-4b
  *** Ifna-gene mRNA[Northern] is increased irt NDV-infection (times)
    *** cells: mEFs in BMS
    *** times: 0 3 6 9+ 12+ 24 hr
    *** reqs: Irf3 [KO]
    *** source: 11070172-Fig-2a
  *** Ifna-gene mRNA[Northern] is increased irt NDV-infection (times)
    *** cells: mEFs in BMS
    *** times: 0 4 8+ 12++ 24 hr
    *** reqs: Irf9 [KO]
    *** reqs: Irf3 and/or Irf9 [KO]
    *** source: 11070172-Fig-4a
  *** Ifna-gene mRNA[Northern] is unchanged irt EMCV-infection (times)
    *** cells: mEFs in BMS
    *** times: 0 6 12 18 hr
    *** unaffected by: Irf3 and/or Irf9 [KO]
    *** source: 11070172-Fig-4c
  *** Ifna-gene mRNA[Northern] is unchanged irt VSV-infection (times)
    *** cells: mEFs in BMS
    *** times: 0 6 12 18 hr
    *** unaffected by: Irf3 and/or Irf9 [KO]
    *** source: 11070172-Fig-4c
  *** Ifna-gene mRNA[RTPCR] is increased itpo xIrf7
    *** cells: mEFs<Stat1~null> in BMS
    *** source: 9822609-Fig-4b
  *** Ifna4-gene mRNA[RTPCR] is detectable
    *** cells: RAW2647<Traf3~kd><xTraf3> in BMS
    *** reqs: xTraf3 [omission]
    *** inhibited by: xTraf3(C68A/H70A) [substitution]
    *** source: 19898473-Fig-5c
  *** Ifna4-gene mRNA[RTPCR] is detectable
    *** cells: RAW2647<Traf3~kd><xTraf3> in BMS
    *** unaffected by: xTraf3(K107R/K156R) [substitution]
    *** source: 19898473-Fig-5f
  *** Ifna4-gene promo-reporter[Luc] is increased itpo xIrf7
    *** cells: HEK293T in BMS
    *** source: 9822609-Fig-3b
  *** Ifna4-gene promo-reporter[Luc] is unchanged itpo xIrf3
    *** cells: HEK293T in BMS
    *** source: 9822609-Fig-3b
  *** Ifna6-gene promo-reporter[Luc] is increased irt xIrf7(del(284-456))
    *** cells: COS<xIrf7(del(284-456))> in BMS
    *** inhibited by: xIrf7 [substitution]
    *** inhibited by: xIrf7(mnr)"alpha" [substitution]
    *** inhibited by: xIrf7(mnr)"gamma" [substitution]
    *** inhibited by: xIrf7(mnr)"delC" [substitution]
    *** source: 11073981-Fig-2a
  *** Ifna6-gene promo-reporter[Luc] is increased itpo xIrf7
    *** cells: COS<xIrf7> in BMS
    *** enhanced by: xIrf7(del(284-456)) [substitution]
    *** source: 11073981-Fig-2b
  *** Ifna6-gene promo-reporter[Luc] is increased itpo xIrf7
    *** cells: HEK293T in BMS
    *** source: 9822609-Fig-3b
  *** Ifna6-gene promo-reporter[Luc] is increased itpo xIrf7(del(284-456))
    *** cells: COS<xIrf7(del(284-456))> in BMS
    *** unaffected by: xIrf7(del(284-456)/S471A/S472A) [substitution]
    *** source: 11073981-Fig-2c
  *** Ifna6-gene promo-reporter[Luc] is increased itpo xIrf7(G91T/T93R)"GTTR"
    *** cells: COS<xIrf7> in BMS
    *** inhibited by: xIrf7 [substitution]
    *** source: 12374802-Fig-4d
  *** Ifna6-gene promo-reporter[Luc] is unchanged itpo xIrf3
    *** cells: HEK293T in BMS
    *** source: 9822609-Fig-3b
  *** xIfnaR2(265-515)[tAb] copptby[WB] xCbp[tAb] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xIfnaR2(265-473) [substitution]
    *** unaffected by: xIfnaR2(265-408) [substitution]
    *** unaffected by: xIfnaR2(265-392) [substitution]
    *** inhibited by: xIfnaR2(265-335) [substitution]
    *** unaffected by: xIfnaR2(336-515) [substitution]
    *** inhibited by: xIfnaR2(392-515) [substitution]
    *** source: 17923090-Fig-1f
  *** IfnaR2[Ab] copptby[WB] Irf9[Ab] is detectable
    *** cells: mEFs in BMS
    *** reqs: Irf9 [KO]
    *** source: 17923090-Fig-3d
  *** xIfnaR2[Ab] copptby[WB] xIrf9[Ab] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xIfnaR2(S322A/S324A) [substitution]
    *** unaffected by: xIfnaR2(S412A/S413A) [substitution]
    *** source: 17923090-Fig-S2a
  *** xIfnaR2[tAb] copptby[WB] xCbp[tAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xIfnaR2(S364A) [substitution]
    *** unaffected by: xIfnaR2(S364D) [substitution]
    *** inhibited by: xIfnaR2(S384A) [substitution]
    *** unaffected by: xIfnaR2(S384D) [substitution]
    *** unaffected by: xIfnaR2(S322A/S324A) [substitution]
    *** unaffected by: xIfnaR2(S400A) [substitution]
    *** unaffected by: xIfnaR2(S412A/S413A) [substitution]
    *** source: 17923090-Fig-1g
  *** xIfnaR2[tAb] copptby[WB] xCbp[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 17923090-Fig-1d
  *** xIfnaR2[tAb] copptby[WB] xEp300[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 17923090-Fig-S1d
  *** xIfnaR2[tAb] copptby[WB] xIrf9[tAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xIfnaR2(265-392) [substitution]
    *** unaffected by: xIfnaR2(265-408) [substitution]
    *** source: 17923090-Fig-3b
  *** xIfnaR2[tAb] copptby[WB] xIrf9[tAb] is detectable
    *** cells: HEK293T in BMS
    *** partially inhibited by: xIfnaR2(K399R) [substitution]
    *** unaffected by: xIfnaR2(S400A) [substitution]
    *** inhibited by: xIfnaR2(K399R/S400A) [substitution]
    *** source: 17923090-Fig-3c
  *** xIfnaR2[tAb] copptby[WB] xIrf9[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 17923090-Fig-3a
  *** xIfnaR2[tAb] copptby[WB] xStat2(265-408)[tAb] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xIfnaR2(265-392) [substitution]
    *** source: 17923090-Fig-3b
  *** xIfnaR2[tAb] copptby[WB] xStat2[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 17923090-Fig-3a
  *** xIfnaR2[tAb]IP acetyl[KAcAb] is increased itpo xCbp
    *** cells: HEK293T in BMS
    *** enhanced by: TrichostatinA [addition]
    *** inhibited by: xHdac6 [addition]
    *** source: 17923090-Fig-2b
  *** xIfnaR2[tAb]IP acetyl[KAcAb] is increased itpo xCbp
    *** cells: HEK293T in BMS
    *** source: 17923090-Fig-2b
  *** xIfnaR2[tAb]IP acetyl[KAcAb] is increased itpo xCbp
    *** cells: HEK293T in BMS
    *** unaffected by: xIfnaR2(K310R) [substitution]
    *** unaffected by: xIfnaR2(K311R) [substitution]
    *** unaffected by: xIfnaR2(K312R) [substitution]
    *** unaffected by: xIfnaR2(K382R) [substitution]
    *** inhibited by: xIfnaR2(K399R) [substitution]
    *** source: 17923090-Fig-2c
  *** xIfnaR2[tAb]IP acetyl[KAcAb] is increased itpo xEp300
    *** cells: HEK293T in BMS
    *** source: 17923090-Fig-2b
  *** xIfnaR2[tAb]IP acetyl[KAcAb] is unchanged itpo xKat2a
    *** cells: HEK293T in BMS
    *** source: 17923090-Fig-2b
  *** xIfnaR2[tAb]IP acetyl[KAcAb] is unchanged itpo xPcaf
    *** cells: HEK293T in BMS
    *** source: 17923090-Fig-2b
  *** Ifnax4-gene mRNA[RTPCR] is increased itpo xIrf7
    *** cells: mEFs<Stat1~null> in BMS
    *** inhibited by: xIrf7(102-457) [substitution]
    *** inhibited by: xIrf7(1-424) [substitution]
    *** source: 9822609-Fig-4c
  *** Ifnax4-gene mRNA[RTPCR] is increased itpo xIrf7
    *** cells: mEFs<Stat1~null> in BMS
    *** source: 9822609-Fig-4b
  *** Ifnax4-gene mRNA[RTPCR] is increased itpo xIrf7(del(284-456))
    *** cells: mEFs<Stat1~null> in BMS
    *** inhibited by: xIrf7 [substitution]
    *** source: 11073981-Fig-4a
  *** Ifnb1-gene mRNA[Northern] is increased irt HSV-infection (times)
    *** cells: mEFs in BMS
    *** times: 0 6 12 18+ hr
    *** reqs: Irf3 and/or Irf9 [KO]
    *** source: 11070172-Fig-4c
  *** Ifnb1-gene mRNA[Northern] is increased irt NDV-infection (8 hr)
    *** cells: mEFs<Irf3~null><xIrf3><Irf9~null><xIrf7> in BMS
    *** does not req: xIrf3 [omission]
    *** does not req: xIrf7 [omission]
    *** reqs: xIrf7 or xIrf3 [omission]
    *** source: 11070172-Fig-5a
  *** Ifnb1-gene mRNA[Northern] is increased irt NDV-infection (8 hr)
    *** cells: mSpCs in BMS
    *** reqs: Irf3 and/or Irf9 [KO]
    *** source: 11070172-Fig-4b
  *** Ifnb1-gene mRNA[Northern] is increased irt NDV-infection (times)
    *** cells: mEFs in BMS
    *** times: 0 3 6 9+ 12+ 24 hr
    *** reqs: Irf3 [KO]
    *** source: 11070172-Fig-2a
  *** Ifnb1-gene mRNA[Northern] is increased irt NDV-infection (times)
    *** cells: mEFs in BMS
    *** times: 0 4 8++ 12++ 24+ hr
    *** partially reqs: Irf9 [KO]
    *** reqs: Irf3 and/or Irf9 [KO]
    *** source: 11070172-Fig-4a
  *** Ifnb1-gene mRNA[Northern] is unchanged irt EMCV-infection (times)
    *** cells: mEFs in BMS
    *** times: 0 6 12+ 18++ hr
    *** reqs: Irf3 and/or Irf9 [KO]
    *** source: 11070172-Fig-4c
  *** Ifnb1-gene mRNA[Northern] is unchanged irt VSV-infection (times)
    *** cells: mEFs in BMS
    *** times: 0 6 12+ 18+ hr
    *** reqs: Irf3 and/or Irf9 [KO]
    *** source: 11070172-Fig-4c
  *** Ifnb1-gene mRNA[RTPCR] is detectable
    *** cells: HELA in BMS "infected with VSV for 12 hr"
    *** inhibited by: xAzi2(158-270)"DN" [addition]
    *** source: 17142768-Fig-6a
  *** Ifnb1-gene mRNA[RTPCR] is detectable
    *** cells: HELA in BMS "infected with VSV for 12 hr"
    *** reqs: Azi2 [RNAi]
    *** source: 17142768-Fig-6c
  *** Ifnb1-gene mRNA[RTPCR] is detectable
    *** cells: RAW2647<Traf3~kd><xTraf3> in BMS
    *** reqs: xTraf3 [omission]
    *** inhibited by: xTraf3(C68A/H70A) [substitution]
    *** source: 19898473-Fig-5c
  *** Ifnb1-gene mRNA[RTPCR] is detectable
    *** cells: RAW2647<Traf3~kd><xTraf3> in BMS
    *** unaffected by: xTraf3(K107R/K156R) [substitution]
    *** source: 19898473-Fig-5f
  *** Ifnb1-gene mRNA[RTPCR] is increased irt RSV-infection (48 hr)
    *** cells: HELA in BMS
    *** does not req: Ikke [RNAi]
    *** source: 17142768-Fig-7a
  *** Ifnb1-gene mRNA[RTPCR] is increased irt RSV-infection (48 hr)
    *** cells: HELA in BMS
    *** does not req: Trif [RNAi]
    *** source: 17142768-Fig-7a
  *** Ifnb1-gene mRNA[RTPCR] is increased irt RSV-infection (48 hr)
    *** cells: HELA in BMS
    *** enhanced by: xTirap(mnr)"DN" [addition]
    *** source: 17142768-Fig-7d
  *** Ifnb1-gene mRNA[RTPCR] is increased irt RSV-infection (48 hr)
    *** cells: HELA in BMS
    *** partially inhibited by: xAzi2(158-270)"DN" [addition]
    *** source: 17142768-Fig-7d
  *** Ifnb1-gene mRNA[RTPCR] is increased irt RSV-infection (48 hr)
    *** cells: HELA in BMS
    *** partially reqs: Azi2 [RNAi]
    *** source: 17142768-Fig-7c
  *** Ifnb1-gene mRNA[RTPCR] is increased irt RSV-infection (48 hr)
    *** cells: HELA in BMS
    *** partially reqs: Mavs [RNAi]
    *** source: 17142768-Fig-7b
  *** Ifnb1-gene mRNA[RTPCR] is increased irt RSV-infection (48 hr)
    *** cells: HELA in BMS
    *** partially reqs: Mda5 [RNAi]
    *** source: 17142768-Fig-7b
  *** Ifnb1-gene mRNA[RTPCR] is increased irt RSV-infection (48 hr)
    *** cells: HELA in BMS
    *** partially reqs: Rig1 [RNAi]
    *** source: 17142768-Fig-7b
  *** Ifnb1-gene mRNA[RTPCR] is increased irt RSV-infection (48 hr)
    *** cells: HELA in BMS
    *** reqs: Tbk1  [RNAi]
    *** source: 17142768-Fig-7a
  *** Ifnb1-gene promo-reporter[CAT] is increased itpo xIrf1
    *** cells: HEK293 in BMS
    *** source: 9566918-Fig-6a
  *** Ifnb1-gene promo-reporter[CAT] is increased itpo xIrf1
    *** cells: HEK293<xRela> in BMS
    *** source: 9566918-Fig-6b
  *** Ifnb1-gene promo-reporter[CAT] is increased itpo xIrf3
    *** cells: HEK293 in BMS
    *** inhibited by: xIrf3(S396A/S398A)"2A" [substitution]
    *** unaffected by: xIrf3(S402A/T404A/S405A)"3A" [substitution]
    *** inhibited by: xIrf3(S396A/S398A/S402A/T404A/S405A)"5A" [substitution]
    *** enhanced by: xIrf3(S396D/S398D/S402D/T404D/S405D)"5D" [substitution]
    *** inhibited by: xIrf3(S385A/S386A)"J2A" [substitution]
    *** inhibited by: xIrf3(S145A/S146A)"NES" [substitution]
    *** enhanced by: xIrf3(1-407) [substitution]
    *** inhibited by: xIrf3(1-394) [substitution]
    *** inhibited by: xIrf3(1-357) [substitution]
    *** source: 9566918-Fig-6a
  *** Ifnb1-gene promo-reporter[CAT] is increased itpo xIrf3
    *** cells: HEK293<xRela> in BMS
    *** inhibited by: xIrf3(S396A/S398A)"2A" [substitution]
    *** unaffected by: xIrf3(S402A/T404A/S405A)"3A" [substitution]
    *** unaffected by: xIrf3(S396A/S398A/S402A/T404A/S405A)"5A" [substitution]
    *** enhanced by: xIrf3(S396D/S398D/S402D/T404D/S405D)"5D" [substitution]
    *** unaffected by: xIrf3(S385A/S386A)"J2A" [substitution]
    *** inhibited by: xIrf3(S145A/S146A)"NES" [substitution]
    *** enhanced by: xIrf3(1-407) [substitution]
    *** inhibited by: xIrf3(1-394) [substitution]
    *** inhibited by: xIrf3(1-357) [substitution]
    *** source: 9566918-Fig-6b
  *** Ifnb1-gene promo-reporter[CAT] is increased itpo xRela
    *** cells: HEK293 in BMS
    *** source: 9566918-Fig-6b
  *** Ifnb1-gene promo-reporter[Luc] is decreased itpo xTrim21
    *** cells: HEK293<xTrif> in BMS
    *** unaffected by: xTrim21(Y343F) [substitution]
    *** reversed by: xTrim21(Y388F) [substitution]
    *** reversed by: xTrim21(Y383F) [substitution]
    *** source: 22476513-Fig-1b
  *** Ifnb1-gene promo-reporter[Luc] is increased irt NDV-infection (tnr)
    *** cells: mEFs<Irf3~null><xIrf3><Irf9~null> in BMS
    *** reqs: xIrf3 [omission]
    *** source: 11070172-Fig-5c
  *** Ifnb1-gene promo-reporter[Luc] is increased irt NDV-infection (tnr)
    *** cells: mEFs<Irf3~null><xIrf7><Irf9~null> in BMS
    *** reqs: xIrf7 [omission]
    *** source: 11070172-Fig-5c
  *** Ifnb1-gene promo-reporter[Luc] is increased itpo xDdx3x
    *** cells: HEK293 in BMS
    *** source: 18636090-Fig-5a
  *** Ifnb1-gene promo-reporter[Luc] is increased itpo xIkke
    *** cells: HEK293 in BMS
    *** enhanced by: xDdx3x [addition]
    *** inhibited by: xDdx3x(1-139) [addition]
    *** source: 18636090-Fig-6a
  *** Ifnb1-gene promo-reporter[Luc] is increased itpo xIkke
    *** cells: HEK293 in BMS
    *** enhanced by: xDdx3x [addition]
    *** inhibited by: xDdx3x(409-662) [addition]
    *** enhanced by: xDdx3x(1-408) [addition]
    *** enhanced by: xDdx3x(1-572) [addition]
    *** inhibited by: xDdx3x(139-572) [addition]
    *** inhibited by: xDdx3x(139-661) [addition]
    *** source: 18636090-Fig-5e
  *** Ifnb1-gene promo-reporter[Luc] is increased itpo xIkke
    *** cells: HEK293 in BMS
    *** enhanced by: xDdx3x [addition]
    *** source: 18636090-Fig-5c
  *** Ifnb1-gene promo-reporter[Luc] is increased itpo xIkke
    *** cells: HEK293 in BMS
    *** enhanced by: xDdx3x(K230E) [addition]
    *** source: 18636090-Fig-5d
  *** Ifnb1-gene promo-reporter[Luc] is increased itpo xIkke
    *** cells: HEK293 in BMS
    *** inhibited by: xIkke(mnr)"KD" [substitution]
    *** source: 14530355-Fig-4a
  *** Ifnb1-gene promo-reporter[Luc] is increased itpo xIkke
    *** cells: HEK293 in BMS
    *** partially reqs: Ddx3x [RNAi]
    *** source: 18636090-Fig-6d
  *** Ifnb1-gene promo-reporter[Luc] is increased itpo xMavs
    *** cells: HEK293 in BMS
    *** inhibited by: xAzi2(158-270)"DN" [addition]
    *** source: 17142768-Fig-4a
  *** Ifnb1-gene promo-reporter[Luc] is increased itpo xMda5
    *** cells: HEK293 in BMS
    *** partially inhibited by: xAzi2(158-270)"DN" [addition]
    *** source: 17142768-Fig-2a
  *** Ifnb1-gene promo-reporter[Luc] is increased itpo xMda5(mnr)"5N"
    *** cells: HEK293 in BMS
    *** partially inhibited by: xAzi2(158-270)"DN" [addition]
    *** source: 17142768-Fig-2a
  *** Ifnb1-gene promo-reporter[Luc] is increased itpo xRig1
    *** cells: HEK293 in BMS
    *** partially inhibited by: xAzi2(158-270)"DN" [addition]
    *** source: 17142768-Fig-2a
  *** Ifnb1-gene promo-reporter[Luc] is increased itpo xRig1(1-229)"CA"
    *** cells: HEK293 in BMS
    *** partially inhibited by: xAzi2(158-270)"DN" [addition]
    *** source: 17142768-Fig-2a
  *** Ifnb1-gene promo-reporter[Luc] is increased itpo xTbk1
    *** cells: HEK293 in BMS
    *** enhanced by: xDdx3x [addition]
    *** source: 18636090-Fig-5b
  *** Ifnb1-gene promo-reporter[Luc] is increased itpo xTbk1
    *** cells: HEK293 in BMS
    *** inhibited by: xTbk1(mnr)"KD" [substitution]
    *** source: 14530355-Fig-4a
  *** Ifnb1-gene promo-reporter[Luc] is increased itpo xTbk1
    *** cells: HEK293 in BMS
    *** partially reqs: Ddx3x [RNAi]
    *** source: 18636090-Fig-6d
  *** Ifnb1-gene promo-reporter[Luc] is increased itpo xTrif
    *** cells: HEK293 in BMS
    *** inhibited by: xTraf6 [addition]
    *** source: 14530355-Fig-5b
  *** Ifnb1-gene promo-reporter[Luc] is increased itpo xTrif
    *** cells: HEK293 in BMS
    *** inhibited by: xTraf6(mnr)"6CT" [addition]
    *** source: 14530355-Fig-3a
  *** Ifnb1-gene promo-reporter[Luc] is increased itpo xTrif
    *** cells: HEK293 in BMS
    *** partially inhibited by: xSrc(K297R)"KD" [addition]
    *** source: 16858407-Fig-1i
  *** Ifnb1-gene promo-reporter[Luc] is increased itpo xTrif
    *** cells: HEK293 in BMS
    *** unaffected by: xTrif(E88A) [substitution]
    *** unaffected by: xTrif(E88A/E252A) [substitution]
    *** unaffected by: xTrif(E88A/E252A/E303A) [substitution]
    *** source: 14530355-Fig-2b
  *** Ifnb1-gene promo-reporter[Luc] is increased itpo xTrif
    *** cells: HEK293 in BMS
    *** unaffected by: xTrif(E88A/E252A/E303A) [substitution]
    *** partially inhibited by: xTrif(mnr)"delC" [substitution]
    *** partially inhibited by: xTrif(E88A/E252A/E303A/mnr)"delC" [substitution]
    *** source: 14530355-Fig-2c
  *** Ifnb1-gene promo-reporter[Luc] is increased itpo xTrif
    *** cells: HEK293<xTLR3> in BMS
    *** inhibited by: xYy1 [addition]
    *** source: 22065573-Fig-5c
  *** Ifnb1-gene promo-reporter[Luc] is increased itpo xTrif + xIrf3
    *** cells: HEK293<xTLR3> in BMS
    *** partially inhibited by: xYy1 [addition]
    *** source: 22065573-Fig-6a
  *** Ifnb1-gene promo-reporter[Luc] is increased itpo xTrif + xIrf7
    *** cells: HEK293<xTLR3> in BMS
    *** inhibited by: xYy1 [addition]
    *** source: 22065573-Fig-6b
  *** Ifnb1-gene promo-reporter[Luc] is increased itpo xTrif(E88A/E252A/E303A)
    *** cells: HEK293 in BMS
    *** unaffected by: xTraf6 [addition]
    *** source: 14530355-Fig-5b
  *** Ifng-gene mRNA[Northern] is detectable
    *** cells: mSpTh1 in BMS
    *** source: 10097133-Fig-2b
  *** Ifng-gene mRNA[Northern] is undetectable
    *** cells: mSpTh2 in BMS
    *** source: 10097133-Fig-2b
  *** Ifng-gene mRNA[RPA] is detectable
    *** cells: mLNCs in BMS "treated with anti-Cd3 for 48 hr"
    *** does not req: Bcl6 [KO]
    *** source: 9110977-Fig-4a
  *** Ifng-gene mRNA[RTPCR] is detectable
    *** cells: mSpTh1 in BMS "treated with ConA 24 hr"
    *** partially inhibited by: SB203580 [cotreatment]
    *** source: 9582275-Fig-3a
  *** Ifng-gene mRNA[RTPCR] is increased itao Stat4 [KO]
    *** cells: mPECs in BMS
    *** source: 11207258-Fig-6c
  *** Ifng-gene promo-reporter[Luc] is decreased itpo xHlx
    *** cells: DERL in BMS "treated with IL12/IL18 for 24 hr"
    *** source: 17110450-Fig-3b
  *** Ifng-gene promo-reporter[Luc] is detectable
    *** cells: JURKAT<Pten~null> in BMS "treated with PMA and Ionomycin for 18 hr"
    *** partially inhibited by: SB203580 [cotreatment]
    *** source: 9582275-Fig-3b
  *** Ifng-gene promo-reporter[Luc] is detectable
    *** cells: JURKAT<Pten~null> in BMS "treated with PMA and Ionomycin for 18 hr"
    *** partially inhibited by: xP38?(mnr)"DN" [addition]
    *** unaffected by: xJnk1(mnr)"DN" [addition]
    *** source: 9582275-Fig-3c
  *** Ifng[Ab] prot-exp[FACS] is detectable
    *** cells: mLCs<Cd4~pos><Lselectin~pos> in BMS "treated with anti-Cd3,anti-Cd28,anti-IL4,IL12/IL2/PMA,Ionomycin"
    *** does not req: Stat6 [KO]
    *** does not req: Irs2 [KO]
    *** does not req: Irs2 or Stat6 [DKO]
    *** source: 11739727-Fig-4a
  *** Ifng[Ab] prot-exp[FACS] is detectable
    *** cells: mLNCs<Cd8~pos> in BMS "treated with anti-Cd3/anti-Cd28 for 7 days followed by PMA/Ionomycin for 24 hr"
    *** unaffected by: Tbet [KO]
    *** source: 11786664-Fig-3b
  *** Ifng[Ab] secretion[ELISA] is decreased itpo xHlx
    *** cells: NK92 in BMS "treated with IL12/IL18 for 24 hr"
    *** source: 17110450-Fig-3b
  *** Ifng[Ab] secretion[ELISA] is detectable
    *** cells: HDK1 in BMS "treated with IL18 and IL2 for 48 hr"
    *** inhibited by: anti-IL18Rap [cotreatment]
    *** source: 11046021-Fig-5
  *** Ifng[Ab] secretion[ELISA] is detectable
    *** cells: hTh1 in BMS "restimulated with anti-Cd3 plus IL2 for 72 hr"
    *** source: 9531298-Fig-1
  *** Ifng[Ab] secretion[ELISA] is detectable
    *** cells: hTh1 in BMS "restimulated with anti-Cd3 plus IL2 for 72 hr"
    *** unaffected by: IL4 [cotreatment]
    *** enhanced by: IL12 [cotreatment]
    *** source: 9531298-Fig-6
  *** Ifng[Ab] secretion[ELISA] is detectable
    *** cells: mCD4TCs in BMS "treated with irradiated splenocytes + anti-Cd3 for tnr"
    *** unaffected by: xFoxp1 [addition]
    *** unaffected by: xFoxp2 [addition]
    *** partially inhibited by: xFoxp3 [addition]
    *** source: 15790681-Fig-1c
  *** Ifng[Ab] secretion[ELISA] is detectable
    *** cells: mLNCs in BMS "treated with anti-Cd3 for 24 hr"
    *** does not req: Bcl6 [KO]
    *** source: 9110977-Fig-4b
  *** Ifng[Ab] secretion[ELISA] is detectable
    *** cells: mLNCs<Cd4~pos> in BMS "treated with anti-Cd3/anti-Cd28 for 7 days restimulated with Cd3/Cd28 for 24 hr"
    *** reqs: Tbet [KO]
    *** source: 11786664-Fig-3c
  *** Ifng[Ab] secretion[ELISA] is detectable
    *** cells: mLNCs<Cd4~pos> in BMS "treated with anti-Cd3/anti-Cd28 for 7 days restimulated with Cd3/Cd28 for 24 hr"
    *** unaffected by: Tbet [KO]
    *** source: 11786664-Fig-3c
  *** Ifng[Ab] secretion[ELISA] is detectable
    *** cells: mLNCs<Cd4~pos> in BMS "treated with anti-Cd3/anti-Cd28 for 72 hr"
    *** reqs: Tbet [KO]
    *** source: 11786664-Fig-1a
  *** Ifng[Ab] secretion[ELISA] is detectable
    *** cells: mLNTCs in BMS "restimulated with anti-Cd3/anti-Cd28 for 24 hr"
    *** reqs: Tbet [KO]
    *** source: 11786664-Fig-1b
  *** Ifng[Ab] secretion[ELISA] is detectable
    *** cells: mLNTh1 in BMS "restimulated with anti-Cd3/anti-Cd28 for 24 hr"
    *** reqs: Tbet [KO]
    *** source: 11786664-Fig-1b
  *** Ifng[Ab] secretion[ELISA] is detectable
    *** cells: mLNTh2 in BMS "restimulated with anti-Cd3/anti-Cd28 for 24 hr"
    *** reqs: Tbet [KO]
    *** source: 11786664-Fig-1b
  *** Ifng[Ab] secretion[ELISA] is detectable
    *** cells: mSpCs in BMS "Th1 diff with (IL12 + anti-IL4)/IL2/anti-TcRb"
    *** partially inhibited by: kIL4R(Y500F) [knockin]
    *** source: 14557412-Fig-4a
  *** Ifng[Ab] secretion[ELISA] is detectable
    *** cells: mSpCs in BMS "Th2 diff with (IL4 + anti-Ifng)/IL2/anti-TcRb"
    *** unaffected by: kIL4R(Y500F) [knockin]
    *** source: 14557412-Fig-4a
  *** Ifng[Ab] secretion[ELISA] is detectable
    *** cells: mSpCs in BMS "treated with IL12 + IL1a for 48 hr"
    *** partially inhibited by: anti-Tnf [cotreatment]
    *** partially inhibited by: anti-IL1a [cotreatment]
    *** inhibited by: anti-IL1b [cotreatment]
    *** source: 7594594-Fig-6a
  *** Ifng[Ab] secretion[ELISA] is detectable
    *** cells: mSpCs in BMS "treated with IL12 + IL1b for 48 hr"
    *** partially inhibited by: anti-Tnf [cotreatment]
    *** unaffected by: anti-IL1a [cotreatment]
    *** inhibited by: anti-IL1b [cotreatment]
    *** source: 7594594-Fig-6a
  *** Ifng[Ab] secretion[ELISA] is detectable
    *** cells: mSpCs in BMS "treated with IL12 + Tnf for 12 hr"
    *** unaffected by: anti-IL1a [cotreatment]
    *** inhibited by: anti-IL1b [cotreatment]
    *** source: 7594594-Fig-4
  *** Ifng[Ab] secretion[ELISA] is detectable
    *** cells: mSpCs in BMS "treated with LPs for 48 hr"
    *** partially inhibited by: anti-IL1R1 [cotreatment]
    *** unaffected by: anti-IL1R2 [cotreatment]
    *** source: 7594594-Table-3
  *** Ifng[Ab] secretion[ELISA] is detectable
    *** cells: mSpCs<Itga2~pos> in BMS "treated with IL12 and IL18 for 72 hr"
    *** partially reqs: Tbet [KO]
    *** source: 11786664-Fig-2a
  *** Ifng[Ab] secretion[ELISA] is detectable
    *** cells: mSpCs<Itga2~pos> in BMS "treated with IL12 for 72 hr"
    *** partially reqs: Tbet [KO]
    *** source: 11786664-Fig-2a
  *** Ifng[Ab] secretion[ELISA] is detectable
    *** cells: mSpTh1 in BMS "treated with anti-Cd3 for 24 hr"
    *** does not req: Stat6 [KO]
    *** source: 8624821-Fig-5a
  *** Ifng[Ab] secretion[ELISA] is detectable
    *** cells: mSpTh1 in BMS "treated with ConA 24 hr"
    *** partially inhibited by: SB203580 [cotreatment]
    *** source: 9582275-Fig-1a
  *** Ifng[Ab] secretion[ELISA] is undetectable
    *** cells: hTh1 in BMS "restimulated with anti-Cd3 plus IL2 for 72 hr"
    *** source: 9531298-Fig-1
  *** Ifng[Ab] secretion[ELISA] is undetectable
    *** cells: hTh1 in BMS "restimulated with anti-Cd3 plus IL2 for 72 hr"
    *** unaffected by: IL4 [cotreatment]
    *** source: 9531298-Fig-6
  *** Ifng[Ab] secretion[ELISA] is undetectable
    *** cells: hTh1 in BMS "restimulated with anti-Cd3, IL2, IL12 for 72 hr"
    *** unaffected by: IL4 [cotreatment]
    *** source: 9531298-Fig-6
  *** Igf2-gene mRNA[RTPCR] is detectable
    *** cells: mEFs in BMS
    *** reqs: Egr1 [KO]
    *** source: 15958557-Fig-1
*** Ikba--
  *** rIkba(1-54)[GST] phos[32P-ATP] is increased by Tbk1[Ab]IP
    *** cells: none
    *** IPfrom: HELA in BMS "treated with PMA for 30 min"
    *** inhibited by: rIkba(1-54/S32A/S36A) [substitution]
    *** unaffected by: rIkba(1-54/S32A) [substitution]
    *** inhibited by: rIkba(1-54/S36A) [substitution]
    *** source: 10783893-Fig-4b
  *** rIkba(1-54)[GST] phos[32P-ATP] is increased by xTbk1[tAb]IP
    *** cells: none
    *** IPfrom: SF9<xTbk1> in BMS
    *** inhibited by: rIkba(1-54/S32A/S36A) [substitution]
    *** unaffected by: rIkba(1-54/S32A) [substitution]
    *** inhibited by: rIkba(1-54/S36A) [substitution]
    *** source: 10783893-Fig-2d
  *** rIkba(1-54)[GST] phos[32P-ATP] is increased by xTbk1[tAb]IP
    *** cells: none
    *** IPfrom: SF9<xTbk1> in BMS
    *** inhibited by: xTbk1(K38M)"KD" [substitution]
    *** source: 10783893-Fig-2d
  *** rIkba(1-100)[32P] phos[32P-ATP] is increased by xNik[tAb]IP
    *** cells: none
    *** IPfrom: HEK293<xNik> in BMS
    *** source: 9520401-Fig-3b
  *** rIkba(1-250)[32P] phos[32P-ATP] is increased by xIkk1[tAb]IP
    *** cells: none
    *** IPfrom: HEK293<xIkk2> in BMS
    *** inhibited by: xIkk1(K44A) [substitution]
    *** source: 9520446-Fig-1a
  *** rIkba(1-250)[32P] phos[32P-ATP] is increased by xIkk2[tAb]IP
    *** cells: none
    *** IPfrom: HEK293<xIkk2> in BMS
    *** inhibited by: xIkk2(K44A) [substitution]
    *** source: 9520446-Fig-1a
  *** rIkba(1-250)[32P] phos[32P-ATP] is unchanged by xNik[tAb]IP
    *** cells: none
    *** IPfrom: HEK293<xNik> in BMS
    *** source: 9520446-Fig-1a
  *** rIkba(5-55)[32P] phos[32P-ATP] is increased by rTbk1
    *** cells: none
    *** inhibited by: rIkba((5-55)/S32A/S36A) [substitution]
    *** source: 14679297-Fig-1a
  *** rIkba[32P] phos[32P-ATP] is unchanged by rNik
    *** cells: none
    *** source: 11520989-Fig-4b
  *** rIkba[32P] phos[32P-ATP] is unchanged by rP38a
    *** cells: none
    *** source: 7535770-Fig-1a
  *** rIkba[32P] phos[32P-ATP] is unchanged by rTbk1
    *** cells: none
    *** source: 14560022-Fig-6a
  *** rIkba[35S] boundby[WB] rKpna1[35S] is undetectable
    *** cells: none
    *** source: 15677444-Fig-5a
  *** rIkba[35S] boundby[WB] rKpna3[35S] is undetectable
    *** cells: none
    *** source: 15677444-Fig-5a
  *** rIkba[35S] boundby[WB] rKpna5[35S] is undetectable
    *** cells: none
    *** source: 15677444-Fig-5a
  *** rIkba[35S] boundby[WB] rKpna6[35S] is undetectable
    *** cells: none
    *** source: 15677444-Fig-5a
  *** rIkba[35S] boundby[WB] rKpnb1[35S] is undetectable
    *** cells: none
    *** source: 15677444-Fig-5a
  *** xIkba[35S] copptby[WB] xNfkb1(1-433)[Ab] is detectable
    *** cells: HEK293<xNfkb1(1-433)><xIkba> in BMS
    *** inhibited by: xNfkb1((1-399)/del(361-366))"delNLS" [substitution]
    *** source: 9566883-Fig-3b
  *** xIkba[35S] copptby[WB] xRela[Ab] is detectable
    *** cells: HEK293<xRela><xIkba> in BMS
    *** unaffected by: xRela(del(301-304))"delNLS" [substitution]
    *** source: 9566883-Fig-3c
  *** Ikba[35S] copptby[WB] xRela[tAb] is decreased itpo xPin1
    *** cells: HELA in BMS
    *** source: 14690596-Fig-3i
  *** rIkba[35S] phos[WBMS] is increased by (rMekk1 + pIKK)
    *** cells: none
    *** source: 11057907(D)
  *** rIkba[35S] phos[WBMS] is increased by (rTraf6 + pIKK + rUbc13 + rUev1a)
    *** cells: none
    *** inhibited by: rUbc13(C87A) [substitution]
    *** source: 11057907(D)
  *** rIkba[35S] phos[WBMS] is increased by (Tab2[Ab]IP + rTraf6 + pIKK + rUbiq + pUbe1 + rUbc13 + rUev1a)
    *** cells: none
    *** IPfrom: HELA in BMS
    *** reqs: rTraf6 [omission]
    *** reqs: rUbc13 and/or rUev1a [omission]
    *** source: 11460167-Fig-1b
  *** rIkba[35S] phos[WBMS] is increased by (xTab2[tAb]IP + rTraf6 + pIKK + rUbiq + pUbe1 + rUbc13 + rUev1a)
    *** cells: none
    *** IPfrom: HELA in BMS
    *** comment: xTab2 IP contains endogenous Tak1
    *** source: 11460167-Fig-1c
  *** rIkba[35S] phos[WBMS] is increased by (xTak1[tAb]IP + rTraf6 + pIKK + rUbiq + pUbe1 + rUbc13 + rUev1a)
    *** cells: none
    *** IPfrom: HELA in BMS
    *** inhibited by: xTak1(K63W)[tAb]IP [substitution]
    *** comment: both xTak1 and xTak1(K63W) IPs contains endogenous Tab2
    *** source: 11460167-Fig-1c
  *** rIkba[35S] phos[WBMS] is increased by xTak1{ubiq}[tAb]IP
    *** cells: none
    *** IPfrom: HELA in BMS
    *** comment: Tak1 IP was ubiquitinated with (rTraf6 + rUbiq + pUbe1 + rUbc13 + rUev1a)
    *** comment: This also works for xTak1{ubiq} ppt with anti-Ub
    *** source: 11460167-Fig-4e
  *** rIkba[35S] phos[WBMS] is unchanged by (rTraf6 + pIKK + rCdc34)
    *** cells: none
    *** source: 11057907(D)
  *** rIkba[35S] phos[WBMS] is unchanged by (rTraf6 + pIKK + rUbe2d3)
    *** cells: none
    *** source: 11057907(D)
  *** rIkba[35S] upshift[WBMS] is increased by (rUbe1 + rUbe2d1 + rUbiq + rRela + rNfkb1 + rIkk? + rMekk1)
    *** cells: none
    *** reqs: rUbe2d1 [omission]
    *** inhibited by: rIkba(S32A/S36A) [substitution]
    *** unaffected by: rIkba(K21R/K22R) [substitution]
    *** unaffected by: rIkba(K38R/K47R) [substitution]
    *** source: 9990853-Fig-5a
  *** xIkba[Ab] copptby[WB] xRel(181-361)"delCdelN"[Ab] is detectable
    *** cells: HEK293<xRel(181-361)"delCdelN"><xIkba> in BMS
    *** source: 9566883-Fig-2b
  *** xIkba[Ab] copptby[WB] xRela(189-337)"delCdelN"[Ab] is detectable
    *** cells: HEK293<xRela(189-337)"delCdelN"><xIkba> in BMS
    *** source: 9566883-Fig-2b
  *** Ikba[Ab] locatedin(nucleus)[IHC] is detectable 
    *** cells: HEK293<xNfkb1(1-433)> in BMS
    *** inhibited by: xNfkb1((1-433)/del(361-366))"delNLS" [addition]
    *** source: 9566883-Fig-3a
  *** Ikba[Ab] prot-exp[WB] is decreased irt IL1b (1 hr)
    *** cells: HEK293<xIL1R1><xIL1Rap> in BMS
    *** reqs: IL1R1 [RNAi]
    *** does not req: TgfbR1 [RNAi]
    *** does not req: TgfbR2 [RNAi]
    *** inhibited by: xIkba(S32A/S36A)"SR" [addition]
    *** source: 17360530-Fig-5a
  *** Ikba[Ab] prot-exp[WB] is decreased itpo (xTak1 + xTab1)
    *** cells: HEK293<xIL1R1> in BMS
    *** source: 10882101(D)
  *** Ikba[Ab] prot-exp[WB] is decreased itpo (xTak1 + xTab1)
    *** cells: HELA in BMS
    *** reversed by: xTak1(T187A) [substitution]
    *** reversed by: xTak1(K63W)"KD" [substitution]
    *** source: 15590691-Fig-1b
  *** xIkba[Ab] prot-exp[WB] is decreased itpo xMdm2
    *** cells: mEFs<Tp53~null><Mdm2~null><xIkba> in BMS
    *** source: 12963717-Fig-4a
  *** Ikba[Ab] prot-exp[WB] is decreased itpo xTnfaip3
    *** cells: HEK293<xTLR4><xMd2> in BMS
    *** source: 21220427-Fig-7a
  *** Ikba[Ab] prot-exp[WB] is unchanged itpo xTp53
    *** cells: SAOS2 in BMS
    *** source: 15073170-Fig-2c
  *** Ikba[Ab] prot-exp[WB] is unchanged itpo xTraf2
    *** cells: HELA in BMS
    *** unaffected by: xUbc13 [addition]
    *** source: 14713952-Fig-3d
  *** Ikba[Ab] prot-stability[CHX-WB] is decreased itao Cebpb [KO]
    *** cells: mSPImacs in BMS
    *** source: 19733238-Fig-4b
  *** Ikba[Ab] prot-stability[CHX-WB] is unchanged itao Cebpb [KO]
    *** cells: mSPImacs in BMS "pretreated with Tnf for 1 hr"
    *** source: 19733238-Fig-4a
  *** xIkba[phosAb] phos(S32)[phosAb] is increased itpo xMekk2
    *** cells: HELA in BMS
    *** source: 10085062-Fig-1b
  *** Ikba[phosAb] phos(S32/S36)[phosAb] is detectable
    *** cells: HEPG2 in BMLS "plated on collagen"
    *** unaffected by: Gefitinib [cotreatment]
    *** unaffected by: PD325901 [cotreatment]
    *** partially inhibited by: BMS345541 [cotreatment]
    *** unaffected by: PHA818637 [cotreatment]
    *** unaffected by: ZSTK474 [cotreatment]
    *** source: 19953085-Fig-S1
  *** Ikba[phosAb] phos(S32/S36)[phosAb] is unchanged itpo xTp53
    *** cells: SAOS2 in BMS
    *** source: 15073170-Fig-2d
  *** Ikba[phosAb] phos(sitenr)[phosAb] is detectable
    *** cells: MCF7 in BMS "cytoplasmic fraction"
    *** reqs: Muc1 [RNAi]
    *** source: 18037881-Fig-1e
  *** Ikba[phosAb] phos(sitenr)[phosAb] is detectable
    *** cells: ZR751 in BMS "cytoplasmic fraction"
    *** reqs: Muc1 [RNAi]
    *** source: 18037881-Fig-1e
  *** Ikba[phosAb] phos(sitenr)[phosAb] is increased itpo xMuc1
    *** cells: HCT116 in BMS "cytoplasmic fraction"
    *** source: 18037881-Fig-1e
  *** Ikba[phosAb] phos(sitenr)[phosAb] is increased itpo xMuc1
    *** cells: HELA in BMS "cytoplasmic fraction"
    *** source: 18037881-Fig-1e
  *** Ikba[phosAb] phos(sitenr)[phosAb] is increased itpo xTraf6
    *** cells: mEFs in BMLS
    *** inhibited by: xTraf6(C70A)"E3-mut" [substitution]
    *** inhibited by: xTraf6(K124R) [substitution]
    *** unaffected by: xTraf6(K133R) [substitution]
    *** unaffected by: xTraf6(K142R) [substitution]
    *** source: 17135271-Fig-6b
  *** xIkba[tAb] phos[WBMS] is increased itpo xMekk2
    *** cells: HELA in BMS
    *** inhibited by: xIkba(S32A/S36A) [substitution]
    *** source: 10085062-Fig-1b
  *** xIkba[tAb] phos[WBMS] is increased itpo xMekk3
    *** cells: HELA in BMS
    *** inhibited by: xIkba(S32A/S36A) [substitution]
    *** source: 10085062-Fig-1b
  *** xIkba[tAb] prot-exp[WB] is decreased itpo xIkk2
    *** cells: HEK293T in BMS
    *** reversed by: xIkba(D31A) [substitution]
    *** partially reversed by: rIkba(D31E) [substitution]
    *** partially reversed by: rIkba(G33A) [substitution]
    *** reversed by: rIkba(S32A/S36A) [substitution]
    *** source: 10514433-Fig-3
  *** xIkba[tAb] prot-stability[35S-pulse-chase] is decreased itpo xIkk2
    *** cells: HEK293T<xBtrc> in BMS
    *** reversed by: xIkba(D31A) [substitution]
    *** partially reversed by: rIkba(D31E) [substitution]
    *** partially reversed by: rIkba(G33A) [substitution]
    *** reversed by: rIkba(S32A/S36A) [substitution]
    *** source: 10514433-Fig-4
  *** xIkba[tAb]IP phos(S32)[phosAb] is increased itpo (xTbk1 + Btrc)
    *** cells: HEK293T<xIkba> in BMS
    *** inhibited by: xIkk2(mnr)"KD" [addition]
    *** source: 10783893-Fig-2c
  *** xIkba[tAb]IP phos(S32)[phosAb] is increased itpo xBtrc
    *** cells: HEK293T<xIkba> in BMS
    *** unaffected by: xIkk2 [addition]
    *** source: 10783893-Fig-2a
  *** xIkba[tAb]IP phos(S32)[phosAb] is increased itpo xTbk1
    *** cells: HEK293T<xIkba> in BMS
    *** enhanced by: xIkk2 [addition]
    *** unaffected by: xBtrc [addition]
    *** source: 10783893-Fig-2a
  *** xIkba[tAb]IP phos(S32)[phosAb] is increased itpo xTbk1
    *** cells: HEK293T<xIkba> in BMS
    *** inhibited by: xTbk1(K38M)"KD" [substitution]
    *** source: 10783893-Fig-2a
  *** xIkba[tAb]IP phos(S32)[phosAb] is unchanged itpo xIkk2
    *** cells: HEK293T<xIkba> in BMS
    *** unaffected by: xBtrc [addition]
    *** source: 10783893-Fig-2a
  *** xIkba[tAb]IP ubiq[UbAb] is increased itpo (xTbk1 + xBtrc)
    *** cells: HEK293T<xIkba> in BMS
    *** reqs: xTbk1 [omission]
    *** reqs: xBtrc [omission]
    *** inhibited by: xTbk1(K38M)"KD" [substitution]
    *** enhanced by: xIkk2 [addition]
    *** source: 10783893-Fig-2a
  *** xIkba[tAb]IP ubiq[UbAb] is increased itpo (xTbk1 + xIkk2)
    *** cells: HEK293T<xIkba> in BMS
    *** reqs: xTbk1 [omission]
    *** reqs: xIkk2 [omission]
    *** enhanced by: xBtrc [addition]
    *** source: 10783893-Fig-2a
  *** xIkba[tAb]IP ubiq[UbAb] is increased itpo xIkk2
    *** cells: HEK293T in BMS
    *** inhibited by: xIkba(D31A) [substitution]
    *** partially inhibited by: rIkba(D31E) [substitution]
    *** partially inhibited by: rIkba(G33A) [substitution]
    *** inhibited by: rIkba(S32A/S36A) [substitution]
    *** source: 10514433-Fig-3
  *** xIkba[tAb]IP upshift[WBMS] is unchanged by xCyld[tAb]IP
    *** cells: none
    *** comment: IPs were from separate transfection of HEK293T
    *** comment: xIkba was ubiqed by xIkk2 + MG132
    *** source: 12917691-Fig-3e
*** Ikbb--
  *** rIkbb(1-120)[32P] phos[32P-ATP] is increased by xNik[tAb]IP
    *** cells: none
    *** IPfrom: HEK293<xIkk2> in BMS
    *** source: 9520401-Fig-3b
  *** rIkbb[35S] boundby[WB] rPkac?[GST] is detectable
    *** cells: none
    *** source: 9150141-Fig-3c
  *** Ikbb[Ab] copptby[WB] Pkacs[Ab] is detectable
    *** cells: 70Z3 in BMS
    *** source: 9150141-Fig-2d
  *** Ikbb[Ab] copptby[WB] Pkars[Ab] is undetectable
    *** cells: 70Z3 in BMS
    *** source: 9150141-Fig-2d
  *** Ikbe-gene mRNA[RTPCR] is detectable
    *** cells: THP1 in BMS
    *** reqs: Ampka1 [RNAi]
    *** source: 22833096-Fig-4d
  *** rIkbe(1-61)[32P] phos[32P-ATP] is increased by xIkk1[tAb]IP
    *** cells: none
    *** IPfrom: HEK293<xIkk1><xNik> in BMS
    *** inhibited by: rIkbe(1-61/S18A/S22A) [substitution]
    *** source: 9520401-Fig-3c
  *** rIkbe(1-61)[32P] phos[32P-ATP] is increased by xIkk2[tAb]IP
    *** cells: none
    *** IPfrom: HEK293<xIkk2><xNik> in BMS
    *** source: 9520401-Fig-3b
  *** rIkbe(1-61)[32P] phos[32P-ATP] is unchanged by xIkk1[tAb]IP
    *** cells: none
    *** IPfrom: HEK293<xIkk1> in BMS
    *** unaffected by: rIkbe(1-61/S18A/S22A) [substitution]
    *** source: 9520401-Fig-3c
  *** rIkbe(1-61)[32P] phos[32P-ATP] is unchanged by xIkk2[tAb]IP
    *** cells: none
    *** IPfrom: HEK293<xIkk2> in BMS
    *** source: 9520401-Fig-3b
  *** rIkbe(1-61)[32P] phos[32P-ATP] is unchanged by xIkk2[tAb]IP
    *** cells: none
    *** IPfrom: HEK293<xIkk2> in BMS
    *** unaffected by: rIkbe(1-61/S18A/S22A) [substitution]
    *** source: 9520401-Fig-3a
  *** rIkbe(1-61)[32P] phos[32P-ATP] is unchanged by xNik[tAb]IP
    *** cells: none
    *** IPfrom: HEK293<xIkk2> in BMS
    *** source: 9520401-Fig-3b
*** Ikbkap--
  *** rIkk1 IVKA(Ikba)[32P-ATP] is detectable-but unchanged by PS1145
    *** cells: none
    *** source: 15199157-Fig-1c
*** Ikk1--
  *** rIkk1[32P] phos[32P-ATP] is unchanged by xIkk2[tAb]IP
    *** cells: none
    *** IPfrom: COS in BMS
    *** unaffected by: xIkk2(S177E/S181E)[tAb]IP [substitution]
    *** unaffected by: xIkk2(del(560-744)/K44M)[tAb]IP [substitution]
    *** unaffected by: xIkk2(S177A/S181A)[tAb]IP [substitution]
    *** partially inhibited by: xIkk2(K44M)[tAb]IP [substitution]
    *** source: 10779355-Fig-7a
  *** Ikk1[Ab] copptby[WB] Ikk2[Ab] is detectable
    *** cells: HELA in BMS
    *** unaffected by: PMA (30 min) [stim]
    *** source: 10783893-Fig-4c
  *** Ikk1[Ab] copptby[WB] Nemo[Ab] is detectable
    *** cells: HELA in BMS
    *** unaffected by: PMA (30 min) [stim]
    *** source: 10783893-Fig-4c
  *** Ikk1[Ab] copptby[WB] Tbk1[Ab] is undetectable
    *** cells: HELA in BMS
    *** unaffected by: PMA (30 min) [stim]
    *** source: 10783893-Fig-4c
  *** Ikk1[Ab] copptby[WB] xPkr(K296R)[Ab] is detectable
    *** cells: HEK293T<xPkr(K296R)> in BMS
    *** source: 10648614-Fig-7b
  *** Ikk1[Ab] copptby[WB] xStat6[Ab] is undetectable
    *** cells: HEK293T<xStat6> in BMS
    *** source: 10648614-Fig-7b
  *** Ikk1[Ab] prot-exp[WB] is detectable-but unchanged itao Traf2 [KO]
    *** cells: mEFs in BMS
    *** source: 18997792-Fig-3b
  *** Ikk1[Ab] prot-exp[WB] is detectable-but unchanged itao Traf3 [KO]
    *** cells: mEFs in BMS
    *** source: 18997792-Fig-3b
  *** Ikk1[Ab]IP IVKA(Ikba)[32P-ATP] is increased itpo (xTak1 + xTab1)
    *** cells: HEK293 in BMS
    *** inhibited by: rIkba(S32A/S36A) [substitution]
    *** source: 10094049-Fig-5a
  *** Ikk1[Ab]IP IVKA(Ikba)[32P-ATP] is increased itpo (xTak1 + xTab1)
    *** cells: HEK293 in BMS
    *** inhibited by: xNik(K429A/K430A) [addition]
    *** source: 10094049-Fig-5a
  *** Ikk1[Ab]IP IVKA(Ikba)[32P-ATP] is increased itpo (xTak1 + xTab1)
    *** cells: HELA in BMS
    *** inhibited by: xTak1(T187A) [substitution]
    *** inhibited by: xTak1(K63W)"KD" [substitution]
    *** source: 15590691-Fig-1b
  *** Ikk1[Ab]IP IVKA(Ikba)[32P-ATP] is increased itpo xTak1
    *** cells: HELA<xTab1> in BMS
    *** inhibited by: xTab1(1-436)"Nterm" [substitution]
    *** unaffected by: xTab1(437-504)"Cterm" [substitution]
    *** source: 10838074-Fig-5b
  *** Ikk1[Ab]IP IVKA(Ikba)[32P-ATP] is increased itpo xTak1
    *** cells: HELA<xTab1> in BMS
    *** unaffected by: xTak1(23-606) [substitution]
    *** inhibited by: xTak1(T184E/T187E) [substitution]
    *** inhibited by: xTak1(K63W) [substitution]
    *** source: 10838074-Fig-5a
  *** Ikk1[Ab]IP IVKA(Nfkb2)[32P-ATP] is increased itao Nemo [KO]
    *** cells: mEFs in BMS
    *** source: 12387745-Fig-6c
  *** Ikk1[Ab]IP phos[32Pi] is increased itpo xNik
    *** cells: COS in BMS
    *** inhibited by: xNik(K429A/K430A) [substitution]
    *** source: 10779355-Fig-1a
  *** xIkk1[tAb]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xIkk1(K44A) [substitution]
    *** source: 9520446-Fig-1a
  *** xIkk1[tAb]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: HEK293<xIkk1> in BMS
    *** inhibited by: xIkk1(K44A)"KD" [substitution]
    *** inhibited by: xIkk1(S176A) [substitution]
    *** source: 9520446-Fig-4a
  *** xIkk1[tAb]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: HEK293<xTak1><xTab1> in BMS
    *** partially inhibited by: xTpl2(K167M) [addition]
    *** source: 15670770-Fig-3a
  *** xIkk1[tAb]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: HEK293<xTpl2> in BMS
    *** inhibited by: xTak1(K63W) [addition]
    *** source: 15670770-Fig-3a
  *** xIkk1[tAb]IP IVKA(auto)[32P-ATP] is increased itpo xNik
    *** cells: HELA in BMS
    *** source: 9689078-Fig-2a
  *** xIkk1[tAb]IP IVKA(auto)[32P-ATP] is increased itpo xTraf2
    *** cells: HEK293 in BMS
    *** inhibited by: xTpl2(K167M) [addition] no-bkg-control
    *** source: 15670770-Fig-2d
  *** xIkk1[tAb]IP IVKA(auto)[32P-ATP] is increased itpo xTraf6
    *** cells: HEK293 in BMS
    *** inhibited by: xTpl2(K167M) [addition] no-bkg-control
    *** source: 15670770-Fig-2d
  *** xIkk1[tAb]IP IVKA(Ikba)[32P-ATP] is detectable
    *** cells: HEK293<xIkk1> in BMS
    *** inhibited by: xIkk1(K44A)"KD" [substitution]
    *** inhibited by: xIkk1(S176A) [substitution]
    *** source: 9520446-Fig-4a
  *** xIkk1[tAb]IP IVKA(Ikba)[32P-ATP] is detectable
    *** cells: HEK293<xIkk1> in BMS
    *** inhibited by: xIkk1(L462S/L469S)"LZmut" [substitution]
    *** inhibited by: xIkk1(L605R/F606P)"HLHmut" [substitution]
    *** source: 9346241-Fig-6b
  *** xIkk1[tAb]IP IVKA(Ikba)[32P-ATP] is detectable
    *** cells: HEK293<xIkk1> in BMS
    *** source: 9346241-Fig-3a
  *** xIkk1[tAb]IP IVKA(Ikba)[32P-ATP] is detectable
    *** cells: HELA<xIkk1> in BMS
    *** enhanced by: xIkk1(S176E) [substitution]
    *** source: 9520446-Fig-7a
  *** rIkk1[tAb]IP IVKA(Ikba)[32P-ATP] is detectable
    *** cells: none
    *** unaffected by: rIkk1(K44M) [substitution]
    *** source: 9346241-Fig-5a
  *** xIkk1[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xIkk2
    *** cells: HEK293<xIkk1> in BMS
    *** inhibited by: xIkk1(L462S/L469S)"LZmut" [substitution]
    *** inhibited by: xIkk1(L605R/F606P)"HLHmut" [substitution]
    *** source: 9346241-Fig-6b
  *** xIkk1[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xMekk1
    *** cells: HEK293<xIkk1> in BMS
    *** inhibited by: xIkk1(K44A)"KD" [substitution]
    *** source: 9520401-Fig-5a
  *** xIkk1[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xMekk1
    *** cells: HEK293<xIkk1> in BMS
    *** inhibited by: xMekk1(K432M)"KD" [substitution]
    *** source: 9520401-Fig-5a
  *** xIkk1[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xMekk1
    *** cells: HEK293<xIkk1><xIkk2> in BMS
    *** source: 9520401-Fig-5b
  *** xIkk1[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xMekk2
    *** cells: HELA in BMS
    *** source: 10085062-Fig-2a
  *** xIkk1[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xMekk2
    *** cells: HELA in BMS
    *** source: 10085062-Fig-3a
  *** xIkk1[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xMekk3
    *** cells: HELA in BMS
    *** source: 10085062-Fig-2a
  *** xIkk1[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xMekk3
    *** cells: HELA in BMS
    *** source: 10085062-Fig-3a
  *** xIkk1[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xNik
    *** cells: HEK293 in BMS
    *** inhibited by: xNik(mnr)"KD" [substitution]
    *** unaffected by: xIkk1(S176A/S180A) [substitution]
    *** unaffected by: xIkk1(S176A) [substitution]
    *** unaffected by: xIkk1(S180A) [substitution]
    *** source: 10195894-Fig-2c
  *** xIkk1[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xNik
    *** cells: HEK293<xIkk1> in BMS
    *** inhibited by: xIkk1(S176A) [substitution]
    *** inhibited by: xIkk1(K44A)"KD" [substitution]
    *** source: 9520446-Fig-5a
  *** xIkk1[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xNik
    *** cells: HEK293<xIkk1> in BMS
    *** source: 9520401-Fig-5a
  *** xIkk1[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xNik
    *** cells: HEK293<xIkk1><xIkk2> in BMS
    *** source: 9520401-Fig-5b
  *** xIkk1[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xNik
    *** cells: HEK293T<xIkk1> in BMS
    *** unaffected by: xTpl2 [addition]
    *** unaffected by: xTpl2(S400A) [addition]
    *** source: 12138205-Fig-8a
  *** xIkk1[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xNik
    *** cells: HELA in BMS
    *** source: 9689078-Fig-2a
  *** xIkk1[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xNik
    *** cells: HELA in BMS
    *** source: 9819420-Fig-3a
  *** xIkk1[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xNik
    *** cells: HELA in BMS
    *** source: 10085062-Fig-2a
  *** xIkk1[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xNik
    *** cells: HELA in BMS
    *** source: 10085062-Fig-3a
  *** xIkk1[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xNik
    *** cells: HELA<xIkk1> in BMS
    *** source: 9520446-Fig-7c
  *** xIkk1[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xNik
    *** cells: NIH3T3 in BMS
    *** source: 11337492-Fig-2b
  *** xIkk1[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xTpl2
    *** cells: HEK293T<xIkk1> in BMS
    *** inhibited by: xTpl2(S400A) [substitution]
    *** source: 12138205-Fig-6a
  *** xIkk1[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xTpl2
    *** cells: HEK293T<xIkk1> in BMS
    *** inhibited by: xTpl2(S400A) [substitution]
    *** source: 12138205-Fig-8a
  *** xIkk1[tAb]IP IVKA(Ikba)[32P-ATP] is unchanged by rPkca(mnr)"CA"
    *** cells: none
    *** IPfrom: HEK293 in BMS
    *** source: 10022904-Fig-6a
  *** xIkk1[tAb]IP IVKA(Ikba)[32P-ATP] is unchanged by rPkca{act}
    *** cells: none
    *** IPfrom: HEK293 in BMS
    *** comment: Pkca is activated by PS and DAG
    *** source: 10022904-Fig-6a
  *** xIkk1[tAb]IP IVKA(Ikba)[32P-ATP] is unchanged itpo xDbl(495-826)"CA"
    *** cells: NIH3T3 in BMS
    *** source: 11337492-Fig-2b
  *** xIkk1[tAb]IP IVKA(Ikba)[32P-ATP] is unchanged itpo xMlk3
    *** cells: HELA in BMS
    *** source: 10085062-Fig-2a
  *** xIkk1[tAb]IP IVKA(Ikba)[32P-ATP] is unchanged itpo xPkcz
    *** cells: HEK293 in BMS
    *** source: 10022904-Fig-5e
  *** xIkk1[tAb]IP IVKA(Rela)[32P-ATP] is increased itpo (xTak1 + xTab1)
    *** cells: HELA in BMS
    *** source: 10521409-Fig-4c
  *** xIkk1[tAb]IP phos[32Pi] is increased itpo xNik
    *** cells: HEK293 in BMS
    *** inhibited by: xNik(mnr)"KD" [substitution]
    *** unaffected by: xIkk1(S176A/S180A) [substitution]
    *** source: 10195894-Fig-4a
  *** xIkk1[tAb]IP phos[32Pi] is unchanged itpo xIkk2
    *** cells: COS in BMS
    *** unaffected by: xIkk2(S177E/S181E) [substitution]
    *** unaffected by: xIkk2(S177A/S181A) [substitution]
    *** unaffected by: xIkk2(K44M) [substitution]
    *** source: 10779355-Fig-3b
  *** rIkk2 IVKA(Ikba)[32P-ATP] is decreased by PS1145
    *** cells: none
    *** source: 15199157-Fig-1c
  *** rIkk2 IVKA(Ikba)[32P-ATP] is decreased by PS1145
    *** cells: none
    *** source: 15199157-Fig-3d
*** Ikk2--
  *** rIkk2(132-206)[GST] phos[32P-ATP] is increased by xTbk1[tAb]IP
    *** cells: none
    *** IPfrom: SF9<xTbk1> in BMS
    *** inhibited by: xIkk2(132-206/S177A/S181A)"KD" [substitution]
    *** source: 10783893-Fig-2d
  *** rIkk2(132-206)[GST] phos[32P-ATP] is increased by xTbk1[tAb]IP
    *** cells: none
    *** IPfrom: SF9<xTbk1> in BMS
    *** inhibited by: xTbk1(K38M)"KD" [substitution]
    *** source: 10783893-Fig-2d
  *** rIkk2[32P] phos[32P-ATP] is unchanged by xP38?[tAb]IP
    *** cells: none
    *** IPfrom: COS1 in BMS
    *** source: 11429546-Fig-3d
  *** Ikk2[Ab] copptby[WB] Ikk1[Ab] is detectable
    *** cells: HELA in BMS
    *** unaffected by: PMA (30 min) [stim]
    *** source: 10783893-Fig-4c
  *** Ikk2[Ab] copptby[WB] Nemo[Ab] is detectable
    *** cells: HELA in BMS
    *** unaffected by: PMA (30 min) [stim]
    *** source: 10783893-Fig-4c
  *** Ikk2[Ab] copptby[WB] Nemo[Ab] is increased itpo xMuc1
    *** cells: HELA in BMS
    *** source: 18037881-Fig-3b
  *** Ikk2[Ab] copptby[WB] Tbk1[Ab] is undetectable
    *** cells: HELA in BMS
    *** unaffected by: PMA (30 min) [stim]
    *** source: 10783893-Fig-4c
  *** xIkk2[Ab] copptby[WB] xTnfaip3[tAb] is undetectable
    *** cells: HEK293T<xTnfaip3><xIkk2> in BMS
    *** source: 21220427-Fig-8a
  *** Ikk2[Ab] prot-exp[WB] is detectable-but unchanged itao Traf2 [KO]
    *** cells: mEFs in BMS
    *** source: 18997792-Fig-3b
  *** Ikk2[Ab] prot-exp[WB] is detectable-but unchanged itao Traf3 [KO]
    *** cells: mEFs in BMS
    *** source: 18997792-Fig-3b
  *** Ikk2[Ab]IP IVKA(Ikba)[32P-ATP] is increased itpo xMuc1
    *** cells: HELA in BMS
    *** source: 18037881-Fig-3e
  *** Ikk2[Ab]IP IVKA(Ikba)[32P-ATP] is increased itpo xRipk1
    *** cells: mEFs in BMS
    *** reqs: Mekk3 [KO]
    *** source: 11429546-Fig-3g
  *** Ikk2[Ab]IP IVKA(Ikba)[32P-ATP] is increased itpo xTab2
    *** cells: HEK293T<xTraf2><xSmad7(259-325)> in BMS
    *** inhibited by: xSmad7 [substitution]
    *** inhibited by: xSmad7((259-426)/S336G/S337G/Y338H) [substitution]
    *** unaffected by: xSmad7((259-426)/N349A/D351G/S352A/T354A) [substitution]
    *** source: 17384642-Fig-S8
  *** Ikk2[Ab]IP IVKA(Ikba)[32P-ATP] is increased itpo xTab3
    *** cells: HEK293T<xTraf2><xSmad7(259-325)> in BMS
    *** inhibited by: xSmad7 [substitution]
    *** inhibited by: xSmad7((259-426)/S336G/S337G/Y338H) [substitution]
    *** unaffected by: xSmad7((259-426)/N349A/D351G/S352A/T354A) [substitution]
    *** source: 17384642-Fig-S8
  *** Ikk2[Ab]IP IVKA(Ikba)[32P-ATP] is increased itpo xTraf2
    *** cells: mEFs in BMS
    *** reqs: Mekk3 [KO]
    *** source: 11429546-Fig-3g
  *** Ikk2[Ab]IP phos(S181)[phosAb] is increased itpo xMuc1
    *** cells: HELA in BMS
    *** source: 18037881-Fig-3d
  *** xIkk2[tAb] cleavage[WB] is unchanged itpo xCasp8
    *** cells: HEK293 in BMS
    *** source: 10753878-Fig-5b
  *** xIkk2[tAb] locatedin(cytoplasm)[IHC] is detectable
    *** cells: COS7<xNemo> in BMS
    *** unaffected by: xNemo(sumo) [addition]
    *** source: 14651848-Fig-4b
  *** xIkk2[tAb]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xIkk2(K44A) [substitution]
    *** source: 9520446-Fig-1a
  *** xIkk2[tAb]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: HEK293<xIkk2> in BMS
    *** inhibited by: xIkk2(K44A) [substitution]
    *** unaffected by: xIkk2(S177A) [substitution]
    *** source: 9520446-Fig-4b
  *** xIkk2[tAb]IP IVKA(auto)[32P-ATP] is increased by rPkca(mnr)"CA"
    *** cells: none
    *** IPfrom: HEK293 in BMS
    *** source: 10022904-Fig-6c
  *** xIkk2[tAb]IP IVKA(auto)[32P-ATP] is increased itpo xNik
    *** cells: HELA in BMS
    *** source: 9689078-Fig-2a
  *** xIkk2[tAb]IP IVKA(Ikba)[32P-ATP] is decreased itpo xPpp2cb
    *** cells: HEK293 in BMS
    *** reversed by: xIkk2(S177E/S181E) [substitution]
    *** source: 14585847-Fig-3a,3b
  *** xIkk2[tAb]IP IVKA(Ikba)[32P-ATP] is detectable
    *** cells: HEK293<xIkk2> in BMS
    *** inhibited by: xIkk2(K44A) [substitution]
    *** unaffected by: xIkk2(S177A) [substitution]
    *** source: 9520446-Fig-4b
  *** xIkk2[tAb]IP IVKA(Ikba)[32P-ATP] is detectable
    *** cells: HEK293<xIkk2> in BMS
    *** source: 9346241-Fig-3a
  *** rIkk2[tAb]IP IVKA(Ikba)[32P-ATP] is detectable
    *** cells: none
    *** inhibited by: rIkk2(K44M) [substitution]
    *** source: 9346241-Fig-5a
  *** xIkk2[tAb]IP IVKA(Ikba)[32P-ATP] is increased by rPkca
    *** cells: none
    *** IPfrom: HEK293 in BMS
    *** comment: Pkca is activated by PS and DAG
    *** source: 10022904-Fig-6a
  *** xIkk2[tAb]IP IVKA(Ikba)[32P-ATP] is increased by rPkca(mnr)"CA"
    *** cells: none
    *** IPfrom: HEK293 in BMS
    *** source: 10022904-Fig-6a
  *** xIkk2[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xDbl(495-826)"CA"
    *** cells: NIH3T3 in BMS
    *** inhibited by: xPak1(83-149)"DN" [addition]
    *** inhibited by: xNik(mnr)"DN" [addition]
    *** unaffected by: xMekk1(K432M)"DN" [addition]
    *** source: 11337492-Fig-2a,3c,4b
  *** xIkk2[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xMekk1
    *** cells: HEK293<xIkk2> in BMS
    *** inhibited by: xIkk2(K44A)"KD" [substitution]
    *** source: 9520401-Fig-5a
  *** xIkk2[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xMekk1
    *** cells: HEK293<xIkk2> in BMS
    *** inhibited by: xMekk1(K432M)"KD" [substitution]
    *** source: 9520401-Fig-5a
  *** xIkk2[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xMekk2
    *** cells: HELA in BMS
    *** source: 10085062-Fig-2b
  *** xIkk2[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xMekk2
    *** cells: HELA in BMS
    *** source: 10085062-Fig-3b
  *** xIkk2[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xNik
    *** cells: COS1 in BMS
    *** partially inhibited by: xIkk1(L506R/F606P)"HLH-mutant" [addition]
    *** source: 9819420-Fig-4b
  *** xIkk2[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xNik
    *** cells: HEK293 in BMS
    *** inhibited by: xNik(mnr)"KD" [substitution]
    *** source: 10195894-Fig-2c
  *** xIkk2[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xNik
    *** cells: HEK293<xIkk2> in BMS
    *** source: 9520401-Fig-5a
  *** xIkk2[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xNik
    *** cells: HELA in BMS
    *** enhanced by: xMekk1(352-1514)"CA" [addition]
    *** source: 9819420-Fig-6c
  *** xIkk2[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xNik
    *** cells: HELA in BMS
    *** inhibited by: xMekk1((352-1514)/K432M)"KD" [addition]
    *** source: 9819420-Fig-7a
  *** xIkk2[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xNik
    *** cells: HELA in BMS
    *** source: 9689078-Fig-2a
  *** xIkk2[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xNik
    *** cells: HELA in BMS
    *** source: 9819420-Fig-3a
  *** xIkk2[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xNik
    *** cells: HELA in BMS
    *** source: 9819420-Fig-6a
  *** xIkk2[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xNik
    *** cells: HELA in BMS
    *** source: 10085062-Fig-2b
  *** xIkk2[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xNik
    *** cells: HELA in BMS
    *** source: 10085062-Fig-3b
  *** xIkk2[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xNik
    *** cells: NIH3T3 in BMS
    *** source: 11337492-Fig-3c
  *** xIkk2[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xPkcz
    *** cells: HEK293 in BMS
    *** source: 10022904-Fig-5a
  *** xIkk2[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xRac1(Q61L)"CA"
    *** cells: NIH3T3 in BMS
    *** inhibited by: xPak1(83-149)"DN" [addition]
    *** inhibited by: xNik(mnr)"DN" [addition]
    *** unaffected by: xMekk1(K432M)"DN" [addition]
    *** source: 11337492-Fig-3b,3C,4b
  *** xIkk2[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xRhoa(G14V)"CA"
    *** cells: NIH3T3 in BMS
    *** source: 11337492-Fig-3b
  *** xIkk2[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xTbk1
    *** cells: HEK293T<xIkk2> in BMS
    *** inhibited by: xTbk1(K38M)"KD" [substitution]
    *** source: 10783893-Fig-2e
  *** xIkk2[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xTpl2
    *** cells: HEK293T<xIkk2> in BMS
    *** inhibited by: xTpl2(S400A) [substitution]
    *** source: 12138205-Fig-6a
  *** xIkk2[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xTraf2
    *** cells: HEK293 in BMS
    *** source: 10346818-Fig-4d
  *** xIkk2[tAb]IP IVKA(Ikba)[32P-ATP] is increased itpo xTraf2
    *** cells: HELA in BMS
    *** unaffected by: xTraf2(C49A/H51A/C209A/C212A) [substitution]
    *** source: 14713952-Fig-2c
  *** xIkk2[tAb]IP IVKA(Ikba)[32P-ATP] is unchanged itpo xCdc42(G12V)"CA"
    *** cells: NIH3T3 in BMS
    *** source: 11337492-Fig-3b
  *** xIkk2[tAb]IP IVKA(Ikba)[32P-ATP] is unchanged itpo xMlk3
    *** cells: HELA in BMS
    *** source: 10085062-Fig-2b
  *** xIkk2[tAb]IP IVKA(Ikba)[32P-ATP] is unchanged itpo xPak1(T423E)"CA"
    *** cells: NIH3T3 in BMS
    *** source: 11337492-Fig-3d
  *** xIkk2[tAb]IP phos[32Pi] is increased itpo xNik
    *** cells: HEK293 in BMS
    *** inhibited by: xNik(mnr)"KD" [substitution]
    *** inhibited by: xIkk2(K44A)"KD" [substitution]
    *** source: 10195894-Fig-4a
*** Ikke--
  *** Ikke[Ab] copptby[WB] Nfkb2[Ab] is detectable-but unchanged irt Tnf (24 hr)
    *** cells: HELA in BMS
    *** source: 17003035-Fig-2c
  *** Ikke[Ab] infraction(P100)[WB] is detectable
    *** cells: HELA in BMLS
    *** source: 21464307-Fig-5c
  *** Ikke[Ab] infraction(P100)[WB] is detectable
    *** cells: HELA in BMS
    *** source: 21464307-Fig-5c
  *** Ikke[Ab] infraction(P100)[WB] is detectable
    *** cells: MDCK2 in BMS
    *** source: 21464307-Fig-5c
   *** xIkke[Ab]IP IVKA(auto)][32P-ATP] is detectable
    *** cells: HEK293<xIkke> in BMS
    *** source: 17003035-Fig-4c
   *** xIkke[Ab]IP IVKA(auto)][32P-ATP] is detectable
    *** cells: HEK293<xIkke> in BMS
    *** source: 17003035-Fig-5d
  *** Ikke[Ab]IP IVKA(Ikba)[32P-ATP] is detectable
    *** cells: mEFs in BMS
    *** unaffected by: Lps (10,30 min) [stim]
    *** source: 12736252-Fig-3c
  *** xIkke[tAb] snaggedby[WB] rDdx3x(1-139)[His] is detectable
    *** cells: HEK293T<xIkke> in BMS
    *** source: 18636090-Fig-6g
  *** xIkke[tAb]IP IVKA(Akt1)(S473)[phosAb] is detectable
    *** cells: HELA<xIkke> in BMS
    *** inhibited by: xIkke(mnr)"KD" [substitution]
    *** source: 21464307-Fig-S5c
*** Ikks--
  *** Ikks[phosAb] phos(S176/S180)[phosAb] is increased itpo xIkke
    *** cells: HEK293 in BMS
    *** source: 16199137-Fig-3b
  *** Ikks[phosAb] phos(sitenr)[phosAb] is detectable
    *** cells: mBMfDCs in BMS
    *** reqs: Irf8 [KO]
    *** source: 15153500-Fig-4a
  *** Ikzf3[Ab] snaggedby[WB] rHras{GDP}[GST] is detectable
    *** cells: TS1<xIL2Ra><xIL2Rb> in BMS "containing IL2" "cytoplasmic-extracts"
    *** enhanced by: IL2-deprivation (tnr) [stress]
    *** source: 10369681-Fig-3b
  *** Ikzf3[Ab] snaggedby[WB] rHras{GTPgS}[GST] is detectable
    *** cells: TS1<xIL2Ra><xIL2Rb> in BMS "containing IL2" "cytoplasmic-extracts"
    *** inhibited by: IL2-deprivation (tnr) [stress]
    *** source: 10369681-Fig-3c
  *** Ikzf3[Ab] snaggedby[WB] rVav?(mnr)"SH2"[GST] is undetectable
    *** cells: TS1<xIL2Ra><xIL2Rb> in BMS "containing IL2" "cytoplasmic-extracts"
    *** unaffected by: IL2-deprivation (tnr) [stress]
    *** source: 10369681-Fig-3b
  *** Ikzf3[Ab] snaggedby[WB] rVav?(mnr)"SH2"[GST] is undetectable
    *** cells: TS1<xIL2Ra><xIL2Rb> in BMS "containing IL2" "cytoplasmic-extracts"
    *** unaffected by: IL2-deprivation (tnr) [stress]
    *** source: 10369681-Fig-3c
*** IL1b--
  *** rIL1b[Ab] cleavage[WB] is increased by rCasp1
    *** cells: none
    *** comment: rILb has bands at 35K and 28K
    *** comment: rILb cleaved by rCasp1 produces an two smaller fragments
    *** source: 9121587-Fig-1a
  *** xIL1b[Ab] cleavage[WB] is increased itpo xNalp1
    *** cells: HEK293<xPycard> in BMS
    *** reqs: xPycard [omission]
    *** source: 15030775(D)
  *** xIL1b[Ab] cleavage[WB] is increased itpo xNlrp3
    *** cells: HEK293<xPycard> in BMS
    *** reqs: xPycard [omission]
    *** source: 15030775(D)
  *** xIL1b[Ab] cleavage[WB] is increased itpo xRac1(G12V)"CA"
    *** cells: HEK293<xCasp1><xIL1b> in BMS
    *** source: 15060067(D)
  *** xIL1b[Ab] secretion[ELISA] is decreased itpo xPyrin
    *** cells: PT67<xCasp1> in BMS
    *** source: 16785446(D)
  *** xIL1b[Ab] secretion[ELISA] is increased itpo xCasp1
    *** cells: PT67 in BMS
    *** source: 16785446(D)
  *** IL1b[Ab] secretion[ELISA] is increased itpo xPycard
    *** cells: HEK293<xCasp1><xRipk2> in BMS
    *** inhibited by: xPycard(del(CardDom)) [substitution]
    *** source: 16585594-Fig-2a
  *** xIL1b[Ab] secretion[ELISA] is increased itpo xPycard
    *** cells: HEK293<xRipk2><xCasp1> in BMS
    *** source: 16585594-Fig-1b
  *** IL1b[Ab] secretion[ELISA] is unchanged itpo xPyrin
    *** cells: HEK293<xCasp1><xPycard><xRipk2> in BMS
    *** source: 16585594-Fig-2a
  *** IL1b[Ab] secretion[ELISA] is unchanged itpo xRipk2
    *** cells: HEK293<xCasp1> in BMS
    *** source: 16585594-Fig-2a
  *** IL1b[Ab] secretion[ELISA] is unchanged itpo xRipk2
    *** cells: HEK293<xCasp1><xPycard> in BMS
    *** source: 16585594-Fig-2a
  *** IL1R1-gene mRNA[RPA] is detectable
    *** cells: hMDDCs in BMS
    *** does not req: TLR2 [KO]
    *** source: 16895974-Fig-3
  *** IL1R1-gene mRNA[RPA] is detectable
    *** cells: hMDDCs in BMS
    *** unaffected by: Lps (5 hr) [stim]
    *** source: 16895974-Fig-1a
  *** IL1R1-gene mRNA[RPA] is detectable
    *** cells: hMDDCs in BMS
    *** unaffected by: Lps (5 hr) [stim]
    *** source: 16895974-Fig-3
  *** IL1Rap-gene mRNA[RTPCR] is detectable
    *** cells: 5E3 in BMS
    *** source: 9759857-Fig-3b
  *** IL1rn-gene mRNA[MicroArray] is detectable
    *** cells: THP1 in BMS
    *** reqs: Ampka1 [RNAi]
    *** source: 22833096-Table-S2a
*** IL2--
  *** rIL2[125I] internalization[Surface-strip] is detectable
    *** cells: BAFB03<xIL2Rb> in BMS
    *** unaffected by: xIL2Rb(del(338-409))"A-mutant" [substitution]
    *** unaffected by: xIL2Rb(1-404)"H-mutant" [substitution]
    *** unaffected by: xIL2Rb(del(292-349))"S-mutant" [substitution]
    *** unaffected by: xIL2Rb(1-281)"ST-mutant" [substitution]
    *** source: 2590941-Fig-6
  *** rIL2[125I] internalization[Surface-strip] is detectable
    *** cells: L929<xIL2Ra><xIL2Rb><xIL2Rg> in BMS
    *** partially reqs: xIL2Ra [omission]
    *** reqs: xIL2Rg [omission]
    *** source: 1631559-Fig-5
  *** IL2[Ab] secretion[ELISA] is detectable
    *** cells: mCD4TCs in BMS "treated with irradiated splenocytes + anti-Cd3 for tnr"
    *** inhibited by: xFoxp3(1-429) [addition]
    *** partially inhibited by: xFoxp3(150-429) [addition]
    *** unaffected by: xFoxp3(200-429) [addition]
    *** source: 15790681-Fig-1d
  *** IL2[Ab] secretion[ELISA] is detectable
    *** cells: mCD4TCs in BMS "treated with irradiated splenocytes + anti-Cd3 for tnr"
    *** unaffected by: xFoxp1 [addition]
    *** enhanced by: xFoxp2 [addition]
    *** inhibited by: xFoxp3 [addition]
    *** source: 15790681-Fig-1a
  *** IL2[Ab] secretion[ELISA] is increased itpo xIrak1
    *** cells: EL4 in BMS "treated with A23187"
    *** unaffected by: xIrak1(T66A) [substitution]
    *** unaffected by: xIrak1(T66D) [substitution]
    *** unaffected by: xIrak1(T66E) [substitution]
    *** unaffected by: xIrak1(T66N) [substitution]
    *** source: 18524972-Fig-2a
  *** IL2R?-gene promo-reporter[Luc] is unchanged itpo xIkzf3
    *** cells: TS1<xIL2Ra><xIL2Rb> in BMS
    *** source: 10369681-Fig-6a
  *** IL2R?-gene promo-reporter[Luc] is unchanged itpo xIkzf3
    *** cells: TS1<xIL2Ra><xIL2Rb> in BMS "containing IL2"
    *** source: 10369681-Fig-6a
*** IL2Ra--
  *** IL2Ra[Ab] surface-exp[FACS] is detectable
    *** cells: mTCs in BMS "treated with anti-Cd3 + anti-Cd28 for 16 hr"
    *** unaffected by: xIkba(mnr)"del-Nterm" [addition]
    *** source: 11160275-Fig-5b
  *** IL2Ra[Ab] surface-exp[FACS] is detectable
    *** cells: mThyCs<TcRa~pos><TcRb~pos> in BMS "treated with PMA + Ionomycin for 20 hr"
    *** unaffected by: xIkba(mnr)"del-Nterm" [addition]
    *** source: 11160275-Fig-5a
*** IL2Rb--
  *** IL2Rb-gene mRNA[Northern] is detectable
    *** cells: H9 in BMS
    *** source: 7721786-Fig-5
  *** IL2Rb-gene mRNA[Northern] is detectable
    *** cells: MOLT4 in BMS
    *** source: 7721786-Fig-5
  *** IL2Rb-gene mRNA[Northern] is detectable
    *** cells: RAJI in BMS
    *** source: 7721786-Fig-5
  *** IL2Rb-gene mRNA[Northern] is undetectable
    *** cells: CAKI1 in BMS
    *** source: 7721786-Fig-5
  *** IL2Rb-gene mRNA[Northern] is undetectable
    *** cells: LCells in BMS
    *** source: 7721786-Fig-5
  *** IL2Rb[Ab] surface-exp[FACS] is detectable
    *** cells: mTCs in BMS "treated with anti-Cd3 + anti-Cd28 for 16 hr"
    *** unaffected by: xIkba(mnr)"del-Nterm" [addition]
    *** source: 11160275-Fig-5b
  *** IL2Rb[Ab] surface-exp[FACS] is detectable
    *** cells: mThyCs<TcRa~pos><TcRb~pos> in BMS "treated with PMA + Ionomycin for 20 hr"
    *** unaffected by: xIkba(mnr)"del-Nterm" [addition]
    *** source: 11160275-Fig-5a
  *** xIL2Rb[Ab]IP IVKA(auto)[32P-ATP] is increased itpo xLck
    *** cells: COS7 in BMS
    *** inhibited by: xIL2Rb(1-404)"H-mutant" [substitution]
    *** inhibited by: xIL2Rb(del(338-409))"A-mutant" [substitution]
    *** unaffected by: xIL2Rb(del(292-349))"S-mutant" [substitution]
    *** inhibited by: xIL2Rb(1-281)"ST-mutant" [substitution]
    *** source: 2047859-Fig-4b
  *** xIL2Rb[Ab]IP IVKA(auto)[32P-ATP] is increased itpo xLck
    *** cells: COS7 in BMS
    *** inhibited by: xIL2Rb(Y381S/Y383S) [substitution]
    *** source: 2047859-Fig-3
  *** xIL2Rb[Ab]IP IVKA(auto)[pYAb] is detectable
    *** cells: COS7<xJak1> in BMS "IL3-deprived" "treated with IL2 for 15 min"
    *** reqs: xJak1 [omission]
    *** source: 8700888-Fig-2c
  *** xIL2Rb[Ab]IP IVKA(auto)[pYAb] is detectable
    *** cells: COS7<xJak1> in BMS "IL3-deprived" "treated with IL2 for 15 min"
    *** unaffected by: xIL2Rb(Y364F/Y381F/Y383F/Y387F)"FFFFYY" [substitution]
    *** inhibited by: xIL2Rb(Y364F/Y381F/Y383F/Y387F/Y418F/Y536F)"FFFFFF" [substitution]
    *** inhibited by: xIL2Rb(Y364F/Y418F/Y536F)"FYYYFF" [substitution]
    *** partially inhibited by: xIL2Rb(Y418F/Y536F)"YYYYFF" [substitution]
    *** source: 8700888-Fig-2c
  *** xIL2Rb[Ab]IP Yphos[pYAb] is detectable
    *** cells: 32D<IL2Rb~null> in BMS "IL3-deprived" "treated with IL2 for 15 min"
    *** unaffected by: xIL2Rb(Y381F/Y383F/Y387F)"YFFFYY" [substitution]
    *** inhibited by: xIL2Rb(Y364F/Y381F/Y383F/Y387F/Y418F/Y536F)"FFFFFF" [substitution]
    *** inhibited by: xIL2Rb(Y364F/Y418F/Y536F)"FYYYFF" [substitution]
    *** partially inhibited by: xIL2Rb(Y418F/Y536F)"YYYYFF" [substitution]
    *** partially inhibited by: xIL2Rb(Y364F/Y381F/Y383F/Y387F)"FFFFYY" [substitution]
    *** source: 8700888-Fig-2b
  *** xIL2Rb[Ab]IP Yphos[pYAb] is increased itpo xJak1
    *** cells: HEK293T in BMS
    *** unaffected by: xCish [addition]
    *** source: 10514520-Fig-6a
  *** xIL2Rb[Ab]IP Yphos[pYAb] is increased itpo xLck(Y505F)"CA"
    *** cells: HEK293T in BMS
    *** partially inhibited by: xCish [addition]
    *** source: 10514520-Fig-6a
  *** xIL2Rb[Ab]IP Yphos[pYAb] is increased itpo xLck(Y505F)"CA"
    *** cells: HEK293T in BMS
    *** partially inhibited by: xCish [addition]
    *** source: 10514520-Fig-6b
  *** xIL2Rb[Ab]IP Yphos[pYAb] is undetectable
    *** cells: HEK293T<xCish> in BMS
    *** source: 10514520-Fig-5
  *** xIL2Rg[35S] copptby[WB] xIL2Rb[Ab] is detectable
    *** cells: L929<xIL2Ra><xIL2Rb><xIL2Rg> in BMS
    *** does not req: xIL2Ra [omission]
    *** source: 1631559-Fig-4
  *** IL2Rg[Ab] surface-exp[FACS] is detectable
    *** cells: CTLL2 in BMS
    *** source: 8266076-Fig-1
  *** IL2Rg[Ab] surface-exp[FACS] is detectable
    *** cells: mTCs in BMS "treated with anti-Cd3 + anti-Cd28 for 16 hr"
    *** unaffected by: xIkba(mnr)"del-Nterm" [addition]
    *** source: 11160275-Fig-5b
  *** IL2Rg[Ab] surface-exp[FACS] is detectable
    *** cells: mThyCs<TcRa~pos><TcRb~pos> in BMS "treated with PMA + Ionomycin for 20 hr"
    *** unaffected by: xIkba(mnr)"del-Nterm" [addition]
    *** source: 11160275-Fig-5a
  *** IL2Rg[Ab] surface-exp[FACS] is undetectable
    *** cells: TART1 in BMS
    *** source: 8266076-Fig-1
  *** IL4-gene mRNA[RPA] is detectable
    *** cells: mLNCs in BMS "treated with anti-Cd3 for 48 hr"
    *** repressed by: Bcl6 [KO]
    *** source: 9110977-Fig-4a
  *** IL4-gene promo-reporter[Luc] is increased itpo xNfatc2 + xMaf + xNip45
    *** cells: M12 in BMS
    *** inhibited by: xFoxp3 [addition]
    *** reqs: xNfatc2 and/or xNip45 [omission]
    *** reqs: xMaf and/or xNip45 [omission]
    *** source: 15790681-Fig-3a
  *** IL4[Ab] prot-exp[FACS] is detectable
    *** cells: mLCs<Cd4~pos><Lselectin~pos> in BMS "treated with anti-Cd3,anti-Cd28,IL4,anti-Ifng/IL2/anti-Cd3"
    *** reqs: Stat6 [KO]
    *** comment: Stat6-null cells express increased Ifng instead
    *** does not req: Irs2 [KO]
    *** source: 11739727-Fig-4a
  *** IL4[Ab] secretion[ELISA] is detectable
    *** cells: hTh1 in BMS "restimulated with anti-Cd3 plus IL2 for 72 hr"
    *** inhibited by: IL4 [cotreatment]
    *** partially inhibited by: IL12 [cotreatment]
    *** source: 9531298-Fig-6
  *** IL4[Ab] secretion[ELISA] is detectable
    *** cells: hTh1 in BMS "restimulated with anti-Cd3 plus IL2 for 72 hr"
    *** source: 9531298-Fig-1
  *** IL4[Ab] secretion[ELISA] is detectable
    *** cells: mCD4TCs in BMS "treated with irradiated splenocytes + anti-Cd3 for tnr"
    *** unaffected by: xFoxp1 [addition]
    *** unaffected by: xFoxp2 [addition]
    *** inhibited by: xFoxp3 [addition]
    *** source: 15790681-Fig-1b
  *** IL4[Ab] secretion[ELISA] is detectable
    *** cells: mLNTCs in BMS "restimulated with anti-Cd3/anti-Cd28 for 24 hr"
    *** repressed by: Tbet [KO]
    *** source: 11786664-Fig-1b
  *** IL4[Ab] secretion[ELISA] is detectable
    *** cells: mLNTh1 in BMS "restimulated with anti-Cd3/anti-Cd28 for 24 hr"
    *** repressed by: Tbet [KO]
    *** source: 11786664-Fig-1b
  *** IL4[Ab] secretion[ELISA] is detectable
    *** cells: mLNTh2 in BMS "restimulated with anti-Cd3/anti-Cd28 for 24 hr"
    *** unaffected by: Tbet [KO]
    *** source: 11786664-Fig-1b
  *** IL4[Ab] secretion[ELISA] is detectable
    *** cells: mSpCs in BMS "Th1 diff with (IL12 + anti-IL4)/IL2/anti-TcRb"
    *** partially inhibited by: kIL4R(Y500F) [knockin]
    *** source: 14557412-Fig-4a
  *** IL4[Ab] secretion[ELISA] is detectable
    *** cells: mSpCs in BMS "Th2 diff with (IL4 + anti-Ifng)/IL2/anti-TcRb"
    *** unaffected by: kIL4R(Y500F) [knockin]
    *** source: 14557412-Fig-4a
  *** IL4[Ab] secretion[ELISA] is detectable
    *** cells: mSpTh1 in BMS "treated with anti-Cd3 for 24 hr"
    *** reqs: Stat6 [KO]
    *** source: 8624821-Fig-5b
  *** IL4[Ab] secretion[ELISA] is detectable
    *** cells: mSpTh1 in BMS "treated with anti-Cd3 for 24 hr"
    *** reqs: Stat6 [KO]
    *** source: 8624821-Fig-5c
  *** IL4[Ab] secretion[ELISA] is detectable
    *** cells: mSpTh1 in BMS "treated with ConA 24 hr"
    *** partially inhibited by: SB203580 [cotreatment]
    *** source: 9582275-Fig-1a
  *** IL4[Ab] secretion[ELISA] is increased itao Bcl6 [KO]
    *** cells: mLNCs in BMS "treated with anti-Cd3 for 24 hr"
    *** source: 9110977-Fig-4b
  *** IL4[Ab] secretion[ELISA] is increased itpo xNfatc2 + xMaf + xNip45
    *** cells: M12 in BMS
    *** inhibited by: xFoxp3 [addition]
    *** reqs: xNfatc2 and/or xNip45 [omission]
    *** reqs: xMaf and/or xNip45 [omission]
    *** source: 15790681-Fig-3a
  *** IL4[Ab] secretion[ELISA] is undetectable
    *** cells: hTh1 in BMS "restimulated with anti-Cd3 plus IL2 for 72 hr"
    *** source: 9531298-Fig-1
  *** IL4[Ab] secretion[ELISA] is undetectable
    *** cells: hTh1 in BMS "restimulated with anti-Cd3 plus IL2 for 72 hr"
    *** unaffected by: IL4 [cotreatment]
    *** unaffected by: IL12 [cotreatment]
    *** source: 9531298-Fig-6
  *** IL4R[Ab] surface-exp[FACS] is detectable
    *** cells: mTCs in BMS "treated with anti-Cd3 + anti-Cd28 for 16 hr"
    *** partially inhibited by: xIkba(mnr)"del-Nterm" [addition]
    *** source: 11160275-Fig-5b
  *** IL4R[Ab] surface-exp[FACS] is detectable
    *** cells: mThyCs<TcRa~pos><TcRb~pos> in BMS "treated with PMA + Ionomycin for 20 hr"
    *** partially inhibited by: xIkba(mnr)"del-Nterm" [addition]
    *** source: 11160275-Fig-5a
  *** IL5-gene mRNA[RPA] is detectable
    *** cells: mLNCs in BMS "treated with anti-Cd3 for 48 hr"
    *** repressed by: Bcl6 [KO]
    *** source: 9110977-Fig-4a
  *** IL5[Ab] prot-exp[FACS] is detectable
    *** cells: mLCs<Cd4~pos><Lselectin~pos> in BMS "treated with anti-Cd3,anti-Cd28,IL4,anti-Ifng/IL2/anti-Cd3"
    *** reqs: Stat6 [KO]
    *** comment: Stat6-null cells express increased Ifng instead
    *** partially reqs: Irs2 [KO]
    *** source: 11739727-Fig-4a
  *** IL5[Ab] secretion[ELISA] is detectable
    *** cells: hTh1 in BMS "restimulated with anti-Cd3 plus IL2 for 72 hr"
    *** source: 9531298-Fig-1
  *** IL5[Ab] secretion[ELISA] is detectable
    *** cells: hTh1 in BMS "restimulated with anti-Cd3 plus IL2 for 72 hr"
    *** unaffected by: IL4 [cotreatment]
    *** partially inhibited by: IL12 [cotreatment]
    *** source: 9531298-Fig-6
  *** IL5[Ab] secretion[ELISA] is detectable
    *** cells: mLNTCs in BMS "restimulated with anti-Cd3/anti-Cd28 for 24 hr"
    *** repressed by: Tbet [KO]
    *** source: 11786664-Fig-1b
  *** IL5[Ab] secretion[ELISA] is detectable
    *** cells: mLNTh1 in BMS "restimulated with anti-Cd3/anti-Cd28 for 24 hr"
    *** repressed by: Tbet [KO]
    *** source: 11786664-Fig-1b
  *** IL5[Ab] secretion[ELISA] is detectable
    *** cells: mLNTh2 in BMS "restimulated with anti-Cd3/anti-Cd28 for 24 hr"
    *** unaffected by: Tbet [KO]
    *** source: 11786664-Fig-1b
  *** IL5[Ab] secretion[ELISA] is detectable
    *** cells: mSpCs in BMS "Th1 diff with (IL12 + anti-IL4)/IL2/anti-TcRb"
    *** partially inhibited by: kIL4R(Y500F) [knockin]
    *** source: 14557412-Fig-4a
  *** IL5[Ab] secretion[ELISA] is detectable
    *** cells: mSpCs in BMS "Th2 diff with (IL4 + anti-Ifng)/IL2/anti-TcRb"
    *** unaffected by: kIL4R(Y500F) [knockin]
    *** source: 14557412-Fig-4a
  *** IL5[Ab] secretion[ELISA] is detectable
    *** cells: mSpTh1 in BMS "treated with anti-Cd3 for 24 hr"
    *** reqs: Stat6 [KO]
    *** source: 8624821-Fig-5b
  *** IL5[Ab] secretion[ELISA] is detectable
    *** cells: mSpTh1 in BMS "treated with anti-Cd3 for 24 hr"
    *** reqs: Stat6 [KO]
    *** source: 8624821-Fig-5c
  *** IL5[Ab] secretion[ELISA] is increased itao Bcl6 [KO]
    *** cells: mLNCs in BMS "treated with anti-Cd3 for 24 hr"
    *** source: 9110977-Fig-4b
  *** IL5[Ab] secretion[ELISA] is undetectable
    *** cells: hTh1 in BMS "restimulated with anti-Cd3 plus IL2 for 72 hr"
    *** source: 9531298-Fig-1
  *** IL5[Ab] secretion[ELISA] is undetectable
    *** cells: hTh1 in BMS "restimulated with anti-Cd3 plus IL2 for 72 hr"
    *** unaffected by: IL4 [cotreatment]
    *** unaffected by: IL12 [cotreatment]
    *** source: 9531298-Fig-6
*** IL6--
  *** IL6-gene mRNA[RTPCR] is detectable
    *** cells: RAW2647<Traf3~kd> in BMS
    *** inhibited by: xTraf3 [addition]
    *** inhibited by: xTraf3(C68A/H70A) [addition]
    *** source: 19898473-Fig-5c
  *** IL6-gene mRNA[RTPCR] is detectable
    *** cells: RAW2647<Traf3~kd><xTraf3> in BMS
    *** partially inhibited by: xTraf3(K107R/K156R) [substitution]
    *** source: 19898473-Fig-5f
  *** IL6[Ab] secretion[ELISA] is increased itpo xNfkbiz
    *** cells: mEFs<Nfkbiz~null> in BMS
    *** source: 15241416-Fig-2g
  *** IL6[Ab] secretion[ELISA] is increased itpo xTirap
    *** cells: hMDMacs in BMS
    *** source: 14630816(D)
  *** IL8-gene mRNA[MicroArray] is detectable
    *** cells: THP1 in BMS
    *** reqs: Ampka1 [RNAi]
    *** source: 22833096-Table-S2a
  *** IL8-gene promo-reporter[Luc] is increased itpo (xTak1 + xTab1)
    *** cells: HELA in BMS
    *** comment: inhibited by removal of Ap1 binding site on IL8-gene promo-reporter
    *** comment: inhibited by removal of Nfkb binding site on IL8-gene promo-reporter
    *** source: 11050078-Fig-3a
  *** IL8-gene promo-reporter[Luc] is increased itpo (xTak1 + xTab1)
    *** cells: HELA in BMS
    *** inhibited by: xJnk2(K55R) [addition]
    *** source: 11050078-Fig-2c
  *** IL8-gene promo-reporter[Luc] is increased itpo (xTak1 + xTab1)
    *** cells: HELA in BMS
    *** inhibited by: xJnk2(K55R) [addition]
    *** source: 11050078-Fig-2d
  *** IL8-gene promo-reporter[Luc] is increased itpo (xTak1 + xTab1)
    *** cells: HELA in BMS
    *** inhibited by: xTab1(1-418) [substitution]
    *** source: 11050078-Fig-7a
  *** IL8-gene promo-reporter[Luc] is increased itpo (xTak1 + xTab1)
    *** cells: HELA in BMS
    *** inhibited by: xTak1(1-77) [substitution]
    *** source: 11050078-Fig-7a
  *** IL8-gene promo-reporter[Luc] is increased itpo (xTak1 + xTab1)
    *** cells: HELA in BMS
    *** reqs: both [omission]
    *** inhibited by: xTak1(K63W) [substitution]
    *** source: 11050078-Fig-2b
  *** IL8-gene promo-reporter[Luc] is increased itpo (xTak1 + xTab1)
    *** cells: HELA in BMS
    *** unaffected by: xP38?(mnr)"AGF" [addition]
    *** source: 11050078-Fig-2d
  *** IL8-gene promo-reporter[Luc] is increased itpo xElk1
    *** cells: cEFs in BMLS
    *** source: 12514134-Fig-1d
  *** IL8-gene promo-reporter[Luc] is increased itpo xEp300
    *** cells: cEFs in BMLS
    *** source: 12514134-Fig-1d
  *** IL8[Ab] secretion[ELISA] is detectable
    *** cells: hPDCs in BMS "treated with CpG-2006 for 48 hr"
    *** unaffected by: anti-IfnaR [cotreatment]
    *** source: 12707322-Fig-4e
  *** IL8[Ab] secretion[ELISA] is detectable
    *** cells: hPDCs in BMS "treated with CpG-2216 for 48 hr"
    *** unaffected by: anti-IfnaR [cotreatment]
    *** source: 12707322-Fig-4e
  *** IL8[Ab] secretion[ELISA] is increased itpo (xTak1 + xTab1)
    *** cells: HELA in BMS
    *** reqs: both [omission]
    *** source: 11050078-Fig-8a
  *** IL10-gene mRNA[RPA] is detectable
    *** cells: mLNCs in BMS "treated with anti-Cd3 for 48 hr"
    *** does not req: Bcl6 [KO]
    *** source: 9110977-Fig-4a
  *** IL10-gene promo-reporter[Luc] is increased itpo xStat3
    *** cells: HELA<xTLR4><xMd2> in BMS
    *** inhibited by: xStat3(S727A) [substitution]
    *** inhibited by: xStat3(Y705F) [substitution]
    *** source: 15465816-Fig-2
  *** IL12[125I] receptor-binding[RIA] is detectable
    *** cells: hPHAblasts in BMS
    *** comment: number of high-affinity sites is increased by Ifng co-blast
    *** source: 9454765-Fig-Table-2
  *** IL12[125I] receptor-binding[RIA] is detectable
    *** cells: mSpDCs in BMS
    *** source: 9768751-Fig-2
  *** IL12[Ab] receptor-binding[FACS] is undetectable
    *** cells: mLNCs<Mhc2s~neg><SIg~neg> in BMS
    *** source: 11466347-Fig-1
  *** rIL12[tAb] receptor-binding[FACS] is detectable
    *** cells: BAF3<xIL12Rb1> in BMS
    *** source: 11114383-Fig-7a
  *** rIL12[tAb] receptor-binding[FACS] is detectable
    *** cells: BAF3<xIL12Rb2> in BMS
    *** source: 11114383-Fig-7c
  *** xIL12a[Ab] oligomerization[NativeWB] is undetectable
    *** cells: COS in BMS
    *** source: 7527811(D)
  *** xIL12b[Ab] oligomerization[NativeWB] is detectable
    *** cells: COS in BMS
    *** source: 7527811(D)
  *** IL12Rb1-gene mRNA[RTPCR] is undetectable
    *** cells: 5E3 in BMS
    *** source: 9759857-Fig-3b
  *** xIL12Rb1[tAb] copptby[WB] xSphk2[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 12874225-Fig-1
  *** IL12Rb2-gene mRNA[Northern] is detectable
    *** cells: hTh1 in BMS
    *** source: 10925275-Fig-7
  *** IL12Rb2-gene mRNA[Northern] is undetectable
    *** cells: hTh2 in BMS
    *** source: 10925275-Fig-7
  *** IL12Rb2-gene mRNA[RTPCR] is detectable
    *** cells: 5E3 in BMS
    *** source: 9759857-Fig-3b
  *** IL12Rb2-gene mRNA[RTPCR] is detectable
    *** cells: mSpCD4TCs in BMS "pretreated with anti-Cd3 + anti-Cd28 + IL12 for 5 days"
    *** repressed by: Stat6 [KO]
    *** partially reqs: Tbet [KO]
    *** source: 19324016-Fig-3a
  *** IL13-gene mRNA[RPA] is detectable
    *** cells: mLNCs in BMS "treated with anti-Cd3 for 48 hr"
    *** repressed by: Bcl6 [KO]
    *** source: 9110977-Fig-4a
  *** IL13[125I] receptor-binding[RIA] is detectable
    *** cells: CHO<xIL13Ra1> in BMS
    *** comment: cannot be displaced by IL4
    *** source: 9013879-Fig-3
  *** IL13[125I] receptor-binding[RIA] is detectable
    *** cells: CHO<xIL13Ra1><xIL4R> in BMS
    *** comment: can be displaced by IL4
    *** source: 9013879-Fig-3
  *** IL13[125I] receptor-binding[RIA] is detectable
    *** cells: DH in BMS
    *** source: 7721786-Table-1
  *** IL13[125I] receptor-binding[RIA] is detectable
    *** cells: HLRCC in BMS
    *** source: 7721786-Table-1
  *** IL13[125I] receptor-binding[RIA] is detectable
    *** cells: hPBMonos in BMS
    *** source: 7721786-Table-1
  *** IL13[125I] receptor-binding[RIA] is detectable
    *** cells: MARCC in BMS
    *** source: 7721786-Table-1
  *** IL13[125I] receptor-binding[RIA] is detectable
    *** cells: PMRCC in BMS
    *** source: 7721786-Table-1
  *** IL13[125I] receptor-binding[RIA] is detectable
    *** cells: TF1 in BMS
    *** source: 7721786-Table-1
  *** IL13[125I] receptor-binding[RIA] is detectable
    *** cells: WSRCC in BMS
    *** source: 7721786-Table-1
  *** IL13[125I] receptor-binding[RIA] is undetectable
    *** cells: H9 in BMS
    *** source: 7721786-Table-1
  *** IL13[125I] receptor-binding[RIA] is undetectable
    *** cells: hPBMCs in BMS "treated with IL2 for 3 days"
    *** source: 7721786-Table-1
  *** IL13[125I] receptor-binding[RIA] is undetectable
    *** cells: MLA144 in BMS
    *** source: 7721786-Table-1
  *** IL13[125I] receptor-binding[RIA] is undetectable
    *** cells: MOLT4 in BMS
    *** source: 7721786-Table-1
  *** IL13[125I] receptor-binding[RIA] is undetectable
    *** cells: RAJI in BMS
    *** source: 7721786-Table-1
  *** IL13[125I] receptor-binding[RIA] is undetectable
    *** cells: U937 in BMS
    *** source: 7721786-Table-1
  *** IL13[Ab] secretion[ELISA] is detectable
    *** cells: mSpCs in BMS "Th1 diff with (IL12 + anti-IL4)/IL2/anti-TcRb"
    *** partially inhibited by: kIL4R(Y500F) [knockin]
    *** source: 14557412-Fig-4a
  *** IL13[Ab] secretion[ELISA] is detectable
    *** cells: mSpCs in BMS "Th2 diff with (IL4 + anti-Ifng)/IL2/anti-TcRb"
    *** unaffected by: kIL4R(Y500F) [knockin]
    *** source: 14557412-Fig-4a
  *** IL13[Ab] secretion[ELISA] is increased itao Bcl6 [KO]
    *** cells: mLNCs in BMS "treated with anti-Cd3 for 24 hr"
    *** source: 9110977-Fig-4b
  *** IL15-gene mRNA[RPA] is undetectable
    *** cells: mLNCs in BMS "treated with anti-Cd3 for 48 hr"
    *** source: 9110977-Fig-4a
  *** xIL17Rd[tAb] locatedin(golgi)[IHC] is detectable
    *** cells: COS7<xIL17Rd> in BMS
    *** source: 15239952-Fig-3a
  *** xIL17Rd[tAb] locatedin(golgi)[IHC] is detectable
    *** cells: COS7<xIL17Rd> in BMS
    *** source: 15239952-Fig-5c
  *** IL18[125I] receptor-binding[RIA] is detectable
    *** cells: HEK293<xIL18R1><xIL18Rap> in BMS
    *** source: 11046021-Fig-2a
  *** rIL18[Ab] cleavage[WB] is increased by rCasp1
    *** cells: none
    *** inhibited by: rIL18(D36A)"cleavage-site-mut" [substitution]
    *** comment: rIL18 has bands at 22K and 20K
    *** comment: rIL18 cleaved by rCasp1 produces an 18K fragment
    *** source: 9121587-Fig-1c,1d,2a
  *** rIL18[Ab] cleavage[WB] is increased by rCasp3
    *** cells: none
    *** source: 9121587-Table-1
  *** rIL18[Ab] cleavage[WB] is increased by rCasp4
    *** cells: none
    *** source: 9121587-Table-1
  *** rIL18[Ab] cleavage[WB] is increased by rCasp5
    *** cells: none
    *** source: 9121587-Table-1
  *** rIL18[Ab] cleavage[WB] is unchanged by rCasp2
    *** cells: none
    *** source: 9121587-Table-1
  *** rIL18[Ab] cleavage[WB] is unchanged by rCasp6
    *** cells: none
    *** source: 9121587-Table-1
  *** IL18[Ab] receptor-binding[FACS] is undetectable
    *** cells: mLNCs<Mhc2s~neg><SIg~neg> in BMS
    *** source: 11466347-Fig-1
  *** IL18R1-gene mRNA[Northern] is detectable
    *** cells: hTh1 in BMS
    *** source: 10925275-Fig-7
  *** IL18R1-gene mRNA[Northern] is detectable
    *** cells: mSpTh1 in BMS
    *** reqs: Stat4 [KO]
    *** source: 11120802-Fig-4b
  *** IL18R1-gene mRNA[Northern] is undetectable
    *** cells: hTh2 in BMS
    *** source: 10925275-Fig-7
  *** IL18R1-gene mRNA[Northern] is undetectable
    *** cells: mSpTh2 in BMS
    *** unaffected by: anti-Cd3 (4 hr) [stim]
    *** source: 11120802-Fig-4b
  *** IL18R1-gene mRNA[RTPCR] is detectable
    *** cells: 5E3 in BMS
    *** source: 9759857-Fig-3b
  *** IL18R1[Ab] surface-exp[FACS] is detectable
    *** cells: mLNCs<Mhc2s~neg><SIg~neg> in BMS
    *** does not req: Ifng [KO]
    *** source: 11466347-Fig-1
  *** IL18R1[Ab] surface-exp[FACS] is detectable
    *** cells: mLNCs<Mhc2s~neg><SIg~neg> in BMS
    *** does not req: Stat4 [KO]
    *** source: 11466347-Fig-1
  *** IL18R1[Ab] surface-exp[FACS] is detectable
    *** cells: mSpCD4TCs in BMS
    *** source: 11457889-Fig-1a
  *** IL18R1[Ab] surface-exp[FACS] is detectable
    *** cells: mSpCD4TCs in BMS "treated with anti-Cd3 + IL2 for 48 hr"
    *** source: 11457889-Fig-3b
  *** IL18R1[Ab] surface-exp[FACS] is detectable
    *** cells: mSpCD4TCs in BMS "treated with anti-Cd3 + IL2 for 48 hr"
    *** source: 11457889-Fig-3b
  *** IL18R1[Ab] surface-exp[FACS] is detectable
    *** cells: mSpCD4TCs<Rag2~null> in BMS
    *** source: 11457889-Fig-1a
  *** IL18R1[Ab] surface-exp[FACS] is detectable
    *** cells: mSpCD8TCs in BMS
    *** source: 11457889-Fig-1c
  *** IL18R1[Ab] surface-exp[FACS] is detectable
    *** cells: mSpCs in BMS "treated with anti-Cd3 + IL2 + IL12 for 48 hr"
    *** partially reqs: Ifng [KO]
    *** source: 11457889-Fig-4c
  *** IL18R1[Ab] surface-exp[FACS] is detectable
    *** cells: mSpCs in BMS "treated with anti-Cd3 + IL2 for 48 hr"
    *** does not req: Ifng [KO]
    *** source: 11457889-Fig-4a
  *** IL18R1[Ab] surface-exp[FACS] is detectable
    *** cells: mSpCs in BMS "treated with IL2 + IL12 for 96 hr"
    *** source: 11457889-Fig-2b
  *** IL18R1[Ab] surface-exp[FACS] is detectable
    *** cells: mSpCs in BMS "treated with IL2 + IL18 + IL12 for 96 hr"
    *** source: 11457889-Fig-2b
  *** IL18R1[Ab] surface-exp[FACS] is detectable
    *** cells: mSpCs in BMS "treated with IL2 + IL18 for 96 hr"
    *** source: 11457889-Fig-2b
  *** IL18R1[Ab] surface-exp[FACS] is detectable
    *** cells: mSpCs in BMS "treated with IL2 for 96 hr"
    *** source: 11457889-Fig-2a
  *** IL18R1[Ab] surface-exp[FACS] is detectable
    *** cells: mSpCs<Cd45~pos> in BMS
    *** comment: surface-exp is much less than that in mSpCD4TCs or mSpCD8TCs
    *** source: 11457889-Fig-1d
  *** IL18R1[Ab] surface-exp[FACS] is detectable
    *** cells: mSpCs<Cd161~pos> in BMS
    *** source: 11457889-Fig-1e
  *** IL18Rap-gene mRNA[Northern] is detectable
    *** cells: hTh1 in BMS
    *** source: 10925275-Fig-7
  *** IL18Rap-gene mRNA[Northern] is detectable
    *** cells: mSpCs in BMS "activated with anti-Cd3 for 48 hr"
    *** partially repressed by: Stat4 [KO]
    *** source: 11120802-Fig-4a
  *** IL18Rap-gene mRNA[Northern] is undetectable
    *** cells: hTh2 in BMS
    *** source: 10925275-Fig-7
  *** IL22Ra1-gene mRNA[RTPCR] is undetectable
    *** cells: mSpTh1 in BMS
    *** source: 16982811-Fig-S2
  *** IL22Ra1-gene mRNA[RTPCR] is undetectable
    *** cells: mSpTh2 in BMS
    *** source: 16982811-Fig-S2
  *** IL22Ra1-gene mRNA[RTPCR] is undetectable
    *** cells: mSpTh17 in BMS
    *** source: 16982811-Fig-S2
  *** rIL23[tAb] receptor-binding[FACS] is detectable
    *** cells: BAF3<xIL12Rb1> in BMS
    *** source: 11114383-Fig-7a
  *** rIL23[tAb] receptor-binding[FACS] is detectable
    *** cells: BAF3<xIL12Rb1> in BMS
    *** source: 11114383-Fig-7b
  *** rIL23[tAb] receptor-binding[FACS] is undetectable
    *** cells: BAF3<xIL12Rb2> in BMS
    *** source: 11114383-Fig-7c
  *** Ilk[Ab] copptby[WB] Akt1[Ab] is detectable
    *** cells: DU145 in BMLS
    *** enhanced by: Serum (tnr) [stim]
    *** source: 11313365-Fig-8a
  *** Ilk[Ab] copptby[WB] Mtor[Ab] is undetectable
    *** cells: MDAMB231 in BMS
    *** source: 18339839-Fig-1b
  *** Ilk[Ab] copptby[WB] Mtor[Ab] is undetectable
    *** cells: PC3 in BMS
    *** source: 18339839-Fig-1b
  *** Ilk[Ab] copptby[WB] Pdpk1[Ab] is detectable
    *** cells: DU145 in BMLS
    *** enhanced by: Serum (tnr) [stim]
    *** source: 11313365-Fig-8a
  *** Ilk[Ab] copptby[WB] xPxn[Ab] is detectable
    *** cells: CHOK1 in BMS
    *** source: 11304546-Fig-7
  *** xIlk[tAb] copptby[WB] Akt1[Ab] is detectable
    *** cells: DU145 in BMLS
    *** inhibited by: xIlk(S434A) [substitution]
    *** source: 11313365-Fig-8b
  *** Ina[Ab] colocwith[IHC] Stau1[Ab] is detectable
    *** cells: SHSY5Y in BMS "differentiated with retinoic acid for 7 days"
    *** source: 15121898(D)
  *** Ina[Ab] copptby[WB] xStau1[tAb] is detectable
    *** cells: HEK293T in BMS "infected with vaccinia vTf7-3 virus"
    *** source: 15121898(D)
  *** Ina[MS] copptby[WB] xStau1[tAb] is detectable
    *** cells: HEK293T in BMS "infected with vaccinia vTf7-3 virus"
    *** source: 15121898(D)
  *** rInha[125I] copptby[Xlink] AcvR1[Ab] is undetectable
    *** cells: P19 in BMS
    *** source: 9748228(D)
  *** rInha[125I] copptby[Xlink] AcvR1b[Ab] is detectable
    *** cells: P19 in BMS
    *** source: 9748228(D)
  *** rInha[125I] copptby[Xlink] AcvR2[Ab] is detectable
    *** cells: P19 in BMS
    *** source: 9748228(D)
  *** rInha[125I] copptby[Xlink] AcvR2b[Ab] is detectable
    *** cells: P19 in BMS
    *** source: 9748228(D)
*** InsR--
  *** xInsR[Ab] copptby[WB] xSnx6[tAb] is detectable
    *** cells: COS7 in BMLS
    *** source: 11279102(D)
*** Ipaf--
  *** xIpaf[tAb] copptby[WB] xCasp1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 15107016(D)
  *** xIpaf[tAb] copptby[WB] xIpaf[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 15107016(D)
*** IqGap1--
  *** rIqGap1[35S] boundby[WB] rMek1[His] is detectable
    *** cells: none
    *** source: 16135787-Fig-1b
  *** rIqGap1[35S] boundby[WB] rMek2[His] is detectable
    *** cells: none
    *** source: 16135787-Fig-1b
  *** IqGap1[Ab] colocwith[IHC] Stau1[Ab] is detectable
    *** cells: SHSY5Y in BMS "differentiated with retinoic acid for 7 days"
    *** source: 15121898(D)
  *** xIqGap1[Ab] copptby[WB] xBraf[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 17563371-Fig-2
  *** IqGap1[Ab] copptby[WB] xCdc42(Q61L)"CA"[tAb] is detectable
    *** cells: COS7 in BMLS
    *** source: 9305904(D)
  *** IqGap1[Ab] copptby[WB] xCdc42(Q61L)[tAb] is detectable
    *** cells: COS7<xSrc> in BMS
    *** unaffected by: xSrc(Y530F) [substitution]
    *** source: 14506284-Fig-3l
  *** IqGap1[Ab] copptby[WB] xStau1[tAb] is detectable
    *** cells: HEK293T in BMS "infected with vaccinia vTf7-3 virus"
    *** source: 15121898(D)
  *** IqGap1[MS] copptby[WB] xStau1[tAb] is detectable
    *** cells: HEK293T in BMS "infected with vaccinia vTf7-3 virus"
    *** source: 15121898(D)
*** IqGap2--
  *** xIqGap2[tAb] snaggedby[WB] rCdc42(Q61L)"CA"[GST] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-2
  *** xIqGap2[tAb] snaggedby[WB] rRac1(Q61L)"CA"[GST] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-2
  *** xIqGap2[tAb] snaggedby[WB] rRhoa(Q63L)"CA"[GST] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-2
  *** xIqGap2[tAb] snaggedby[WB] rRhog(Q61L)"CA"[GST] is detectable
    *** cells: NIH3T3 in BMS
    *** inhibited by: rRhog(WT) [substitution]
    *** source: 12376551-Fig-2
*** Irak1--
  *** Irak1-gene mRNA[Northern] is detectable
    *** cells: mSpCs in BMS "activated with anti-Cd3 for 48 hr"
    *** does not req: Stat4 [KO]
    *** source: 11120802-Fig-4a
  *** sIrak1(359-389)[32P] phos[32P-ATP] is unchanged by rNik
    *** cells: none
    *** unaffected by: sIrak1((359-389)/pT387) [substitution]
    *** unaffected by: sIrak1((359-389)/pS376) [substitution]
    *** source: 11960013-Fig-5b
  *** xIrak1(D340N)"KD"[Ab] copptby[WB] (xIL1R1[tAb] + xIL1Rap[tAb]) is detectable
    *** cells: HEK293T<xTollip> in BMS
    *** inhibited by: xIrak1(WT) [substitution]
    *** source: 10854325-Fig-4a
  *** xIrak1(del(104-198))[Ab] copptby[WB] Tak1[Ab] is detectable
    *** cells: HEK293I1A<Irak1~null> in BMS
    *** unaffected by: IL1b (10 min) [stim]
    *** source: 12242293-Fig-4c
  *** xIrak1(mnr)"Nterm"[Ab] upshift[WBMS] is decreased itpo xTollip
    *** cells: HEK293T in BMS
    *** source: 10854325-Fig-3d
  *** xIrak1(T66A)[Ab] copptby[WB] (xIL1R1[tAb] + xIL1Rap[tAb]) is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xIrak1(WT) [substitution]
    *** source: 10854325-Fig-4a
  *** xIrak1(T66A)[Ab] upshift[WBMS] is increased itpo xMyd88
    *** cells: HEK293T in BMS
    *** comment: inhibited by treatment of lysates with PPase
    *** source: 10854325-Fig-4c
  *** xIrak1(T66A)[Ab] upshift[WBMS] is increased itpo xMyd88
    *** cells: HEK293T in BMS
    *** partially inhibited by: xMyd88(mnr)"DD" [substitution]
    *** partially inhibited by: xMyd88(mnr)"TIR" [substitution]
    *** source: 10854325-Fig-4d
  *** rIrak1[32P] phos[32P-ATP] is unchanged by rIrak4(K213A/K214A)"KD"
    *** cells: none
    *** source: 11960013-Fig-5a
  *** rIrak1[35S] upshift[WBMS] is increased by (rTraf6 + pUbe1 + rUbc13 + rUev1a + rUbiq)
    *** cells: none
    *** inhibited by: rIrak1(K134R)"Ubiq-binding-site-mut" [substitution]
    *** unaffected by: rIrak1(K180R)"Ubiq-binding-site-mut" [substitution]
    *** inhibited by: rIrak1(K134R/K180R)"Ubiq-binding-site-mut" [substitution]
    *** source: 18347055-Fig-4a
  *** rIrak1[35S] upshift[WBMS] is increased by (rTraf6 + pUbe1 + rUbc13 + rUev1a + rUbiq)
    *** cells: none
    *** source: 18347055-Fig-3a
  *** Irak1[Ab] copptby[WB] xIL1R1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 9374458-Fig-2c
  *** Irak1[Ab] copptby[WB] xIL1Rap[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 9374458-Fig-2c
  *** xIrak1[Ab] copptby[WB] xNemo[Ab] is increased itpo xPeli2
    *** cells: HEK293<Irak1~null><xIL1R1><xIrak1> in BMLS
    *** comment: only ubiq-Irak1[MW] is coppt
    *** inhibited by: xIrak1(K239S)"KD" [substitution]
    *** inhibited by: xPeli2(H371S/C373A)"ring-domain-mut" [substitution]
    *** inhibited by: xNemo(D311N)"unable to bind to K63-polyUbiq chains" [substitution]
    *** source: 17997719-Fig-5b
  *** xIrak1[Ab] copptby[WB] xTnfaip3[tAb] is detectable
    *** cells: HEK293T<xTnfaip3><xIrak1> in BMS
    *** comment: coppt Irak1 is ubiq [WBMS]
    *** source: 21220427-Fig-8b
  *** Irak1[Ab] copptby[WB] xTraf2[tAb] is undetectable
    *** cells: HEK293<xIL1R1> in BMS
    *** unaffected by: IL1 (tnr) [stim]
    *** source: 8837778-Fig-4a
  *** xIrak1[Ab] ubiq[tUbAb] is increased itpo xPeli1
    *** cells: HEK293T<xUbiq> in BMS
    *** inhibited by: xPeli1(H369S/C371S)"ring-domain-mut" [substitution]
    *** source: 16884718-Fig-3b
  *** xIrak1[Ab] ubiq[tUbAb] is increased itpo xPeli1
    *** cells: HEK293T<xUbiq> in BMS
    *** source: 16884718-Fig-3a
  *** xIrak1[Ab] ubiq[tUbAb] is increased itpo xPeli2
    *** cells: HEK293T<xUbiq> in BMS
    *** inhibited by: xPeli2(H371S/C373S)"ring-domain-mut" [substitution]
    *** source: 16884718-Fig-3b
  *** xIrak1[Ab] ubiq[tUbAb] is increased itpo xPeli2
    *** cells: HEK293T<xUbiq> in BMS
    *** source: 16884718-Fig-3a
  *** xIrak1[Ab] ubiq[tUbAb] is increased itpo xPeli3
    *** cells: HEK293T<xUbiq> in BMS
    *** source: 16884718-Fig-3a
  *** xIrak1[Ab] ubiq[tUbAb] is unchanged itpo xPeli3
    *** cells: HEK293T<xUbiq> in BMS
    *** source: 16884718-Fig-3b
  *** xIrak1[Ab] upshift[WBMS] is detectable
    *** cells: HEK293I1A<Irak1~null> in BMS
    *** inhibited by: xIrak1(K293A)"KD" [substitution]
    *** source: 11518704-Fig-6b
  *** xIrak1[Ab] upshift[WBMS] is detectable
    *** cells: HEK293I1A<Irak1~null> in BMS
    *** inhibited by: xIrak1(K293A)"KD" [substitution]
    *** source: 11518704-Fig-7
  *** xIrak1[Ab] upshift[WBMS] is increased itpo xPeli2
    *** cells: HEK293<Irak1~null><xIL1R1><xIrak1> in BMLS
    *** inhibited by: xPeli2(H371S/C373A)"ring-domain-mut" [substitution]
    *** source: 17997719-Fig-5a
  *** xIrak1[tAb] copptby[WB] xIL1Rap[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 9625770-Fig-3a
  *** xIrak1[tAb] copptby[WB] xMyd88[tAb] is increased itpo xIrak3
    *** cells: HEK293T in BMS
    *** unaffected by: xIrak1(K206A)"KD" [substitution]
    *** source: 12150927-Fig-6c
  *** xIrak1[tAb] copptby[WB] xTraf6[tAb] is increased itpo xTifa
    *** cells: HEK293T in BMS
    *** comment: xTifa inhibits at high concentrations
    *** source: 12566447-Fig-4a
  *** xIrak1[tAb] upshift[WBMS] is decreased itpo xTollip
    *** cells: HEK293<xTLR4><xIrak1> in BMS
    *** source: 11751856(D)
  *** xIrak1[tAb] upshift[WBMS] is increased itpo xPeli2
    *** cells: HEK293 in BMS
    *** inhibited by: xIrak1(K239S)"KD" [substitution]
    *** source: 12860405-Fig-1c
*** Irak2--
  *** Irak2[Ab] copptby[WB] xIL1R1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 9374458-Fig-2c
  *** Irak2[Ab] copptby[WB] xIL1Rap[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 9374458-Fig-2c
  *** Irak2[Ab] copptby[WB] xMyd88[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 9374458-Fig-4d
  *** xIrak2[Ab] copptby[WB] xTollip[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 10854325-Fig-3c
  *** Irak2[Ab] copptby[WB] xTraf2[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 9374458-Fig-3a
  *** Irak2[Ab] copptby[WB] xTraf6[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 9374458-Fig-3a
  *** xIrak2[tAb] copptby[WB] xIL1Rap[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 9625770-Fig-3a
  *** xIrak2[tAb] copptby[WB] xTirap[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 11544529-Fig-3f
  *** xIrak2[tAb] copptby[WB] xTLR4[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 9625770-Fig-3a
  *** xIrak2[tAb] copptby[WB] xTnfaip3[tAb] is detectable
    *** cells: HEK293T<xTnfaip3><xIrak2> in BMS
    *** source: 21220427-Fig-8c
*** Irak3--
  *** xIrak3[tAb] copptby[WB] xMyd88[tAb] is detectable
    *** cells: HEK293T<xIrak1(K206A)"KD"> in BMS
    *** source: 12150927-Fig-6d
  *** xIrak3[tAb] copptby[WB] xMyd88[tAb] is detectable
    *** cells: HEK293T<xIrak1> in BMS
    *** source: 12150927-Fig-6d
  *** xIrak3[tAb] copptby[WB] xTraf6[tAb] is detectable
    *** cells: HEK293T<xIrak1(K206A)"KD"> in BMS
    *** source: 12150927-Fig-6c
  *** xIrak3[tAb] copptby[WB] xTraf6[tAb] is detectable
    *** cells: HEK293T<xIrak1> in BMS
    *** source: 12150927-Fig-6c
*** Irak4--
  *** rIrak4(K213A/K214A)"KD"[32P] phos[32P-ATP] is unchanged by rIrak1
    *** cells: none
    *** source: 11960013-Fig-5a
  *** rIrak4[32P] phos[32P-ATP] is increased by rIrak1(K239S)"KD"
    *** cells: none
    *** source: 11960013-Fig-5a
  *** xIrak4[tAb] copptby[WB] xMyd88[tAb] is increased itpo xIrak3
    *** cells: HEK293T in BMS
    *** source: 12150927-Fig-6e
  *** xIrak4[tAb] copptby[WB] xTnfaip3[tAb] is undetectable
    *** cells: HEK293T<xTnfaip3><xIrak4> in BMS
    *** source: 21220427-Fig-8a
  *** xIrak4[tAb] IVKA(auto)[32P-ATP] is detectable
    *** cells: EL4 in BMS
    *** comment: xIrak4 was phosed on ST but not Y by PAA
    *** source: 17507369-Fig-4b
*** Irf1--
  *** Irf1-gene promo-reporter[Luc] is increased itpo xStat4
    *** cells: NIH3T3<xIL12Rb1><xIL12Rb2> in BMS
    *** source: 10358173-Fig-5c
  *** Irf1-gene promo-reporter[Luc] is unchanged itpo xParp14
    *** cells: HEPG2 in BMS
    *** source: 16537510-Fig-2e
  *** xIrf1[tAb] copptby[WB] xMyd88[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 17018642-Fig-1d
  *** xIrf1[XFP] colocwith[FRET] xMyd88[XFP] is detectable
    *** cells: HEK293T in BMS
    *** source: 17018642-Fig-1c
  *** xIrf1[XFP] locatedin(nucleus)[IHC] is increased itpo xMyd88
    *** cells: HELA in BMS
    *** source: 17018642-Fig-2c
*** Irf2--
  *** xIrf2[tAb] copptby[WB] xMyd88[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 17018642-Fig-1d
  *** xIrf2[XFP] colocwith[FRET] xMyd88[XFP] is undetectable
    *** cells: HEK293T in BMS
    *** source: 17018642-Fig-1c
*** Irf3--
  *** rIrf3(380-427)[32P] phos[32P-ATP] is unchanged by rIkk2
    *** cells: none
    *** source: 14679297-Fig-1a
  *** xIrf3(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMavs
    *** cells: HEK293 in BMS
    *** comment: inhibited by expression of HCV NS3/4A protease
    *** source: 16301520-Fig-1c
  *** xIrf3(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMavs
    *** cells: HEK293 in BMS
    *** source: 16125763-Fig-2b
  *** xIrf3(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xRig1(Nterm)"CA"
    *** cells: HEK293 in BMS
    *** comment: inhibited by expression of HCV NS3/4A protease
    *** source: 16301520-Fig-1c
  *** xIrf3(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xTicam2
    *** cells: HEK293 in BMS
    *** source: 14517278-Fig-2b
  *** xIrf3(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xTirap
    *** cells: U373 in BMS
    *** inhibited by: xTirap(P125H) [substitution]
    *** source: 12062447-Fig-5a
  *** xIrf3(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xTrif
    *** cells: HEK293 in BMS
    *** enhanced by: xTicam2 [addition]
    *** source: 14519765(D)
  *** xIrf3(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xTrif
    *** cells: HEK293 in BMS
    *** inhibited by: xAzi2(158-270)"DN" [addition]
    *** source: 15611223(D)
  *** xIrf3(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xTrif
    *** cells: HEK293 in BMS
    *** source: 14517278-Fig-2b
  *** xIrf3(TAD)[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo (xTLR4 + xMd2 + xCd14)
    *** cells: HEK293 in BMS
    *** source: 15611223-Fig-3d
  *** xIrf3(TAD)[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xIkk2
    *** cells: HEK293T in BMS
    *** source: 12692549-Fig-2a
  *** xIrf3(TAD)[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xRipk2
    *** cells: HEK293 in BMS
    *** source: 16125763-Fig-2b
  *** xIrf3(TAD)[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xTirap
    *** cells: L929 in BMS
    *** source: 12062447-Fig-5f
  *** xIrf3(TAD)[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xTLR3
    *** cells: HEK293 in BMS
    *** source: 15611223-Fig-3c
  *** Irf3[Ab] copptby[WB] xTicam2[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 14517278-Fig-3b
  *** xIrf3[Ab] copptby[WB] xTicam2[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 14517278-Fig-3b
  *** Irf3[Ab] oligomerization[NativeWB] is increased irt VSV-infection (24 hr)
    *** cells: HEK293 in BMS
    *** inhibited by: xAzi2(158-270)"DN" [addition]
    *** source: 17142768-Fig-5b
  *** Irf3[Ab] oligomerization[NativeWB] is increased irt VSV-infection (24 hr)
    *** cells: HELA in BMS
    *** reqs: Azi2 [RNAi]
    *** source: 17142768-Fig-6b
  *** Irf3[Ab] oligomerization[NativeWB] is increased itpo xMavs
    *** cells: HEK293 in BMS
    *** inhibited by: xIrf3(TAD)[Gal4-DBD] [addition]
    *** source: 16301520-Fig-1d
  *** Irf3[Ab] oligomerization[NativeWB] is increased itpo xMavs
    *** cells: HEK293 in BMS
    *** source: 16125763-Fig-2f
  *** Irf3[Ab] oligomerization[NativeWB] is increased itpo xTirap
    *** cells: U373 in BMS
    *** source: 12062447-Fig-5c
  *** Irf3[Ab] oligomerization[NativeWB] is increased itpo xTrif
    *** cells: HEK293 in BMS
    *** inhibited by: xAzi2(158-270)"DN" [addition]
    *** source: 15611223-Fig-3b
  *** Irf3[Ab] oligomerization[NativeWB] is increased itpo xTrif
    *** cells: HEK293 in BMS
    *** source: 14519765(D)
  *** Irf3[Ab] oligomerization[NativeWB] is increased itpo xTrif
    *** cells: HELA in BMS
    *** source: 12539043-Fig-5b
  *** Irf3[Ab] oligomerization[NativeWB] is unchanged itpo xRipk2
    *** cells: HEK293 in BMS
    *** source: 16125763-Fig-2f
  *** Irf3[Ab] oligomerization[NativeWB] is unchanged itpo xTicam2
    *** cells: HEK293 in BMS
    *** source: 14519765(D)
  *** Irf3[Gal4-DBD] Gal4-reporter[Luc] is detectable
    *** cells: HEK293 in BMS
    *** partially inhibited by: xAzi2(158-270)"DN" [addition]
    *** source: 17142768-Fig-2b
  *** Irf3[Gal4-DBD] Gal4-reporter[Luc] is detectable-but unchanged itpo xRig1
    *** cells: HEK293 in BMS
    *** source: 17142768-Fig-2b
  *** Irf3[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMavs
    *** cells: HEK293 in BMS
    *** inhibited by: xAzi2(158-270)"DN" [addition]
    *** source: 17142768-Fig-4b
  *** Irf3[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMda5
    *** cells: HEK293 in BMS
    *** partially inhibited by: xAzi2(158-270)"DN" [addition]
    *** source: 17142768-Fig-2b
  *** Irf3[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMda5(mnr)"5N"
    *** cells: HEK293 in BMS
    *** partially inhibited by: xAzi2(158-270)"DN" [addition]
    *** source: 17142768-Fig-2b
  *** Irf3[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xRig1(1-229)"CA"
    *** cells: HEK293 in BMS
    *** partially inhibited by: xAzi2(158-270)"DN" [addition]
    *** source: 17142768-Fig-2b
  *** Irf3[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xTrif
    *** cells: HEK293 in BMS
    *** source: 18636090-Fig-3b
  *** xIrf3[phosAb] phos(S386)[phosAb] is increased itpo xTrif
    *** cells: HEK293T in BMS
    *** source: 14703513-Fig-3a
  *** xIrf3[tAb] copptby[WB] xMyd88[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 14739303-Fig-1d
  *** xIrf3[tAb] copptby[WB] xMyd88[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 15361868-Fig-1b
  *** xIrf3[tAb] copptby[WB] xMyd88[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15665823-Fig-3c
  *** xIrf3[tAb] copptby[WB] xRig1[tAb] is increased itpo xMavs
    *** cells: HEK293 in BMS
    *** source: 16153868-Fig-4a
  *** xIrf3[tAb] copptby[WB] xTirap[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 14739303-Fig-1d
  *** xIrf3[tAb] copptby[WB] xTraf6[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15665823-Fig-3c
  *** xIrf3[tAb] copptby[WB] xTrif[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 14739303-Fig-1d
  *** xIrf3[tAb] oligomerization[NativeWB] is increased itpo xTrif
    *** cells: HEK293T in BMS
    *** source: 14703513-Fig-3a
  *** xIrf3[tAb] snaggedby[WB] rTrim21(286-466)[GST] is detectable
    *** cells: HEK293T<xIrf3> in BMS
    *** unaffected by: rTrim21(286-466/Y343F) [substitution]
    *** unaffected by: rTrim21(286-466/Y388F) [substitution]
    *** inhibited by: rTrim21(286-466/Y393F) [substitution]
    *** source: 22476513-Fig-3i
  *** xIrf3[tAb]IP acetyl[KAcAb] is unchanged itpo xPcaf
    *** cells: HEK293T<xIrf7> in BMS
    *** source: 12374802-Fig-4b
  *** xIrf3[XFP] colocwith[FRET] xMyd88[XFP] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15492225-Fig-1b
  *** xIrf3[XFP] colocwith[FRET] xMyd88[XFP] is undetectable
    *** cells: HEK293T in BMS
    *** source: 16236719-Fig-1c
*** Irf4--
  *** Irf4[Ab] copptby[WB] Bcl6[Ab] is detectable
    *** cells: JY in BMS "nuclear-extract"
    *** unaffected by: IL4 (24 hr) [stim]
    *** source: 10601358-Fig-5c
  *** xIrf4[tAb] copptby[WB] xMyd88[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 16236719-Fig-1d,2b
  *** xIrf4[XFP] colocwith[FRET] xMyd88[XFP]  is undetectable
    *** cells: HEK293T in BMS
    *** source: 16236719-Fig-1a,1b,1c
*** Irf5--
  *** xIrf5[tAb] copptby[WB] xMyd88[tAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xIrf4 [addition]
    *** unaffected by: xIrf3 [addition]
    *** source: 16236719-Fig-2b
  *** xIrf5[XFP] colocwith[FRET] xMyd88[XFP] is detectable
    *** cells: HEK293T in BMS
    *** source: 16236719-Fig-1c
  *** xIrf5[XFP] colocwith[FRET] xMyd88[XFP] is detectable
    *** cells: HEK293T in BMS
    *** source: 17018642-Fig-1c
*** Irf7--
  *** Irf7-gene mRNA[MicroArray] is detectable
    *** cells: THP1 in BMS
    *** reqs: Ampka1 [RNAi]
    *** source: 22833096-Table-S2a
  *** Irf7-gene mRNA[Northern] is detectable
    *** cells: mEFs in BMS
    *** partially reqs: Irf3 [KO]
    *** reqs: Irf9 [KO]
    *** reqs: IfnaR1 [KO]
    *** source: 11070172-Fig-2e
  *** Irf7-gene mRNA[Northern] is increased irt NDV-infection (12 hr)
    *** cells: mEFs in BMS
    *** partially reqs: Irf3 [KO]
    *** source: 11070172-Fig-2d
  *** Irf7-gene mRNA[Northern] is increased irt NDV-infection (12 hr)
    *** cells: mEFs in BMS
    *** reqs: Irf9 [KO]
    *** source: 11070172-Fig-2d
  *** Irf7-gene mRNA[Northern] is increased irt NDV-infection (times)
    *** cells: mEFs in BMS
    *** times: 0 4 8+ 12++ 24+++ hr
    *** reqs: Irf9 [KO]
    *** reqs: Irf3 and/or Irf9 [KO]
    *** source: 11070172-Fig-4a
  *** rIrf7(TAD)[Ab] boundby[WB] oligo[biotin] is detectable
    *** cells: none
    *** inhibited by: rIrf7(TAD){acetyl} [substitution]
    *** source: 12374802-Fig-5a
  *** xIrf7(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xTicam2
    *** cells: HEK293 in BMS
    *** source: 14517278-Fig-2b
  *** xIrf7(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xTrif
    *** cells: HEK293 in BMS
    *** source: 14517278-Fig-2b
  *** rIrf7[32P] phos[32P-ATP] is increased by xIrak1[tAb]IP
    *** cells: none
    *** IPfrom: HEK293 in BMS
    *** inhibited by: xIrak1(K239A)"KD"[tAb]IP [substitution]
    *** source: 15767370-Fig-2b
  *** rIrf7[32P] phos[32P-ATP] is unchanged by xIrak4[tAb]IP
    *** cells: none
    *** IPfrom: HEK293 in BMS
    *** source: 15767370-Fig-2b
  *** Irf7[Ab] infraction(nuclear)[WB] is detectable
    *** cells: mBMfDCs in BMS
    *** reqs: Spp1 [KO]
    *** source: 16604075-Fig-4a
  *** xIrf7[Gal4-DBD] Gal4-reporter[Luc] is detectable
    *** cells: COS<xIrf7> in BMS
    *** enhanced by: xIrf7(132-457) [substitution]
    *** inhibited by: xIrf7(132-424) [substitution]
    *** inhibited by: xIrf7(1-424) [substitution]
    *** inhibited by: xIrf7(132-367) [substitution]
    *** enhanced by: xIrf7(132-237) [substitution]
    *** unaffected by: xIrf7(132-205) [substitution]
    *** inhibited by: xIrf7(153-457) [substitution]
    *** inhibited by: xIrf7(207-457) [substitution]
    *** enhanced by: xIrf7(132-237/411-457) [substitution]
    *** enhanced by: xIrf7(411-457) [substitution]
    *** comment: aa numbers refer to mouse protein
    *** source: 11073981-Fig-3
  *** Irf7[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xIkke
    *** cells: HEK293 in BMS
    *** inhibited by: xDdx3x(1-139) [addition]
    *** source: 18636090-Fig-6d
  *** Irf7[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xTbk1
    *** cells: HEK293 in BMS
    *** source: 18636090-Fig-3e
  *** Irf7[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xTbk1
    *** cells: HEK293 in BMS
    *** source: 18636090-Fig-3f
  *** Irf7[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xTrif
    *** cells: HEK293 in BMS
    *** source: 18636090-Fig-3a
  *** xIrf7[RE] oligo-binding[EMSA] is increased itpo xPcaf
    *** cells: HEK293T<xIrf7> in BMS "nuclear-extracts"
    *** inhibited by: xIrf7(G91T/T93R)"GTTR" [substitution]
    *** source: 12374802-Fig-4c
  *** xIrf7[tAb] copptby[WB] Myd88[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 15361868-Fig-1e
  *** xIrf7[tAb] copptby[WB] xIkk1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** enhanced by: xTraf6 [addition]
    *** enhanced by: xMyd88 [addition]
    *** source: 16612387-Fig-3c
  *** xIrf7[tAb] copptby[WB] xIrak1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 15767370-Fig-1a,1c
  *** xIrf7[tAb] copptby[WB] xIrak4[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 15767370-Fig-1a
  *** xIrf7[tAb] copptby[WB] xMyd88[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 15361868-Fig-1b
  *** xIrf7[tAb] copptby[WB] xMyd88[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15492225-Fig-3a
  *** xIrf7[tAb] copptby[WB] xMyd88[tAb] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xIrf4 [addition]
    *** unaffected by: xIrf3 [addition]
    *** source: 16236719-Fig-2b
  *** xIrf7[tAb] copptby[WB] xTraf2[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 15361868-Fig-5d
  *** xIrf7[tAb] copptby[WB] xTraf6[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 15361868-Fig-5d
  *** xIrf7[tAb] copptby[WB] xTraf6[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15492225-Fig-3a
  *** xIrf7[tAb]IP acetyl[KAcAb] is increased itpo xKat2a
    *** cells: HEK293T<xIrf7> in BMS
    *** inhibited by: xKat2a(mnr)"HATm" [substitution]
    *** source: 12374802-Fig-1b
  *** xIrf7[tAb]IP acetyl[KAcAb] is increased itpo xPcaf
    *** cells: HEK293T<xIrf7> in BMS
    *** inhibited by: xIrf7(G91T/T93R)"GTTR" [substitution]
    *** inhibited by: xIrf7(mnr)"Cterm" [substitution]
    *** source: 12374802-Fig-4b
  *** xIrf7[tAb]IP acetyl[KAcAb] is increased itpo xPcaf
    *** cells: HEK293T<xIrf7> in BMS
    *** inhibited by: xPcaf(mnr)"HATm" [substitution]
    *** source: 12374802-Fig-1b
  *** xIrf7[tAb]IP acetyl[KAcAb] is increased itpo xPcaf
    *** cells: HEK293T<xIrf7> in BMS
    *** partially inhibited by: xHdac1 [addition]
    *** source: 12374802-Fig-1b
  *** xIrf7[tAb]IP ubiq[UbAb] is increased itpo xTraf6
    *** cells: HEK293 in BMS
    *** reqs: Ubc13 [RNAi]
    *** source: 15361868-Fig-6a,6d
  *** xIrf7[tAb]IP ubiq[UbAb] is unchanged itpo xMyd88
    *** cells: HEK293 in BMS
    *** source: 15361868-Fig-6a
  *** xIrf7[XFP] colocwith[FRET] xIrak1[XFP] is detectable
    *** cells: HEK293 in BMS
    *** source: 15767370-Fig-1b
  *** xIrf7[XFP] colocwith[FRET] xIrak4[XFP] is undetectable
    *** cells: HEK293 in BMS
    *** source: 15767370-Fig-1b
  *** xIrf7[XFP] colocwith[FRET] xMyd88[XFP] is detectable
    *** cells: HEK293T in BMS
    *** source: 16236719-Fig-1c
  *** xIrf7[XFP] colocwith[FRET] xMyd88[XFP] is detectable
    *** cells: HEK293T in BMS
    *** source: 17018642-Fig-1c
  *** xIrf7[XFP] colocwith[IHC] xMyd88[XFP] is detectable
    *** cells: HEK293T in BMS
    *** source: 15492225-Fig-1b
  *** xIrf8[tAb] copptby[WB] xMyd88[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 16236719-Fig-1d
  *** xIrf8[XFP] colocwith[FRET] xMyd88[XFP] is undetectable
    *** cells: HEK293T in BMS
    *** source: 16236719-Fig-1a,1b,1c
*** Irf9--
  *** xIrf9(1-118)[tAb] copptby[WB] xIrf9[tAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xIrf9(118-339) [substitution]
    *** unaffected by: xIrf9(118-393) [substitution]
    *** source: 17923090-Fig-5f
  *** xIrf9(1-118)[tAb] copptby[WB] xIrf9[tAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xIrf9(K81R) [substitution]
    *** unaffected by: xIrf9(K81Q) [substitution]
    *** source: 17923090-Fig-5f
  *** xIrf9(118-339)[tAb] copptby[WB] xIfnaR2[tAb] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xIrf9(118-393) [substitution]
    *** inhibited by: xIrf9(1-117) [substitution]
    *** inhibited by: xIrf9(118-257) [substitution]
    *** source: 17923090-Fig-4c
  *** Irf9[Ab] infraction(nuclear)[WB] is detectable
    *** cells: U5A<IfnaR2~null><xIfnaR2> in BMS
    *** reqs: xIfnaR2 [omission]
    *** unaffected by: Ifna (tnr) [stim]
    *** inhibited by: xIfnaR2(K399R) [substitution]
    *** source: 17923090-Fig-3f
  *** Irf9[Ab]IP acetyl[KAcAb] is decreased itpo xKat2a
    *** cells: HEK293T in BMS
    *** source: 17923090-Fig-5b
  *** Irf9[Ab]IP acetyl[KAcAb] is decreased itpo xPcaf
    *** cells: HEK293T in BMS
    *** source: 17923090-Fig-5b
  *** Irf9[Ab]IP acetyl[KAcAb] is detectable
    *** cells: HELA in BMS
    *** reqs: Cbp [RNAi]
    *** source: 17923090-Fig-5a
  *** Irf9[Ab]IP acetyl[KAcAb] is increased itpo xCbp
    *** cells: HEK293T in BMS
    *** source: 17923090-Fig-5b
  *** Irf9[Ab]IP acetyl[KAcAb] is unchanged itpo xEp300
    *** cells: HEK293T in BMS
    *** source: 17923090-Fig-5b
  *** xIrf9[tAb] copptby[WB] xIfnaR2[tAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xIfnaR2(R292Q) [substitution]
    *** unaffected by: xIfnaR2(W300A) [substitution]
    *** unaffected by: xIfnaR2(F323A/F328A) [substitution]
    *** source: 17923090-Fig-4d
  *** xIrf9[tAb] copptby[WB] xMyd88[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 16236719-Fig-1d
  *** xIrf9[tAb] copptby[WB] xStat1[tAb] is detectable
    *** cells: U6A<Stat2~null><xStat2(K390R)> in BMS
    *** inhibited by: Ifna (30 min) [stim]
    *** source: 17923090-Fig-6i
  *** xIrf9[tAb] copptby[WB] xStat1[tAb] is detectable
    *** cells: U6A<Stat2~null><xStat2> in BMS
    *** inhibited by: xStat2(K390R) [substitution]
    *** source: 17923090-Fig-6i
  *** xIrf9[tAb] copptby[WB] xStat2[tAb] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xIrf9(118-393) [substitution]
    *** inhibited by: xIrf9(1-117) [substitution]
    *** inhibited by: xIrf9(1-339) [substitution]
    *** inhibited by: xIrf9(1-260) [substitution]
    *** source: 17923090-Fig-4d
  *** xIrf9[tAb]IP acetyl[KAcAb] is increased itpo xCbp
    *** cells: U2A<Irf9~null> in BMS
    *** enhanced by: xIrf9(K43R) [substitution]
    *** unaffected by: xIrf9(K47R) [substitution]
    *** enhanced by: xIrf9(K66R) [substitution]
    *** enhanced by: xIrf9(K68R) [substitution]
    *** enhanced by: xIrf9(K81R) [substitution]
    *** unaffected by: xIrf9(K90R) [substitution]
    *** enhanced by: xIrf9(K110R) [substitution]
    *** enhanced by: xIrf9(K128R) [substitution]
    *** enhanced by: xIrf9(K132R) [substitution]
    *** source: 17923090-Fig-5c
  *** xIrf9[XFP] colocwith[FRET] xMyd88[XFP] is undetectable
    *** cells: HEK293T in BMS
    *** source: 16236719-Fig-1c
*** Irs1--
  *** rIrs1(511-772)[32P] phos[32P-ATP] is increased by xMtor[tAb]IP
    *** cells: none
    *** comment: Mtor-IP is from HEK293 in BMS
    *** inhibited by: xMtor(S2035T/D2357E)"KD" [substitution]
    *** inhibited by: rFkbp12 + Rapamycin [addition]
    *** source: 11162588-Fig-1a
  *** Irs1[Ab] prot-exp[WB] is detectable
    *** cells: 3T3L1 in BMS
    *** reqs: Pras40 [RNAi]
    *** source: 17277771-Fig-2a
  *** Irs1[Ab] prot-exp[WB] is detectable
    *** cells: 3T3L1 in BMS
    *** reqs: Pras40 [RNAi]
    *** source: 17277771-Fig-3b
  *** Irs1[Ab] prot-exp[WB] is detectable
    *** cells: HEPG2 in BMS
    *** reqs: Pras40 [RNAi]
    *** source: 17277771-Fig-2a
  *** Irs1[Ab] prot-exp[WB] is detectable
    *** cells: RPMI8226 in BMS
    *** reqs: Deptor [RNAi]
    *** source: 19446321-Fig-6e
  *** Irs1[Ab]IP phos(S307)[phosAb] is detectable
    *** cells: mEFs in BMLS
    *** reqs: Jnk1 and/or Jnk2 [DKO]
    *** source: 12417588-Fig-3
  *** xIrs1[Ab]IP Yphos[pYAb] is increased itpo xFes
    *** cells: HEK293T in BMS
    *** unaffected by: xJak1(mnr)"KD" [addition]
    *** source: 11160325-Fig-7
  *** xIrs1[Ab]IP Yphos[pYAb] is increased itpo xFes
    *** cells: HEK293T in BMS
    *** unaffected by: xJak3(mnr)"KD" [addition]
    *** source: 11160325-Fig-7
  *** xIrs1[Ab]IP Yphos[pYAb] is increased itpo xJak1
    *** cells: HEK293T in BMS
    *** inhibited by: xFes(K590E)"KD" [addition]
    *** source: 11160325-Fig-7
  *** xIrs1[Ab]IP Yphos[pYAb] is increased itpo xJak1
    *** cells: HEK293T in BMS
    *** unaffected by: xJak3(mnr)"KD" [addition]
    *** source: 11160325-Fig-7
  *** xIrs1[Ab]IP Yphos[pYAb] is increased itpo xJak3
    *** cells: HEK293T in BMS
    *** inhibited by: xFes(K590E)"KD" [addition]
    *** source: 11160325-Fig-7
  *** xIrs1[Ab]IP Yphos[pYAb] is increased itpo xJak3
    *** cells: HEK293T in BMS
    *** unaffected by: xJak1(mnr)"KD" [addition]
    *** source: 11160325-Fig-7
  *** Irs1[phosAb] phos(S307)[phosAb] is decreased itpo xTsc1
    *** cells: MDAMB453 in BMLS
    *** unaffected by: xTsc1(mnr)"SSAA" [substitution]
    *** reversed by: xTsc1(mnr)"SSAA" [substitution]
    *** source: 18949383-Fig-1c
  *** Irs1[phosAb] phos(S307)[phosAb] is detectable
    *** cells: 32D<xInsR><xIrs1> in BMS
    *** inhibited by: xIrs1(L856G/L858G) [substitution]
    *** source: 12417588-Fig-5a
  *** Irs1[phosAb] phos(S636/S639)[phosAb] is decreased itpo xTsc1
    *** cells: MDAMB453 in BMLS
    *** unaffected by: xTsc1(mnr)"SSAA" [substitution]
    *** reversed by: xTsc1(mnr)"SSAA" [substitution]
    *** source: 18949383-Fig-1c
  *** Irs1[phosAb] phos(S636/S639)[phosAb] is detectable
    *** cells: HEPG2 in BMLS "plated on collagen"
    *** unaffected by: Gefitinib [cotreatment]
    *** partially inhibited by: PD325901 [cotreatment]
    *** unaffected by: BMS345541 [cotreatment]
    *** unaffected by: PHA818637 [cotreatment]
    *** unaffected by: ZSTK474 [cotreatment]
    *** source: 19953085-Fig-S1
*** Isg15--
  *** Isg15-gene mRNA[RTPCR] is detectable
    *** cells: mEFs in BMS
    *** reqs: Cbp [KO]
    *** source: 17923090-Fig-7e
  *** Isg15-gene mRNA[RTPCR] is detectable
    *** cells: U3A<Stat1~null><xStat1(K410R/K413R)> in BMS "treated with Ifna for 8 hr"
    *** enhanced by: ValproicAcid [addition]
    *** source: 19171783-Fig-3h
  *** Isg15-gene mRNA[RTPCR] is detectable
    *** cells: U3A<Stat1~null><xStat1> in BMS "treated with Ifna for 8 hr"
    *** inhibited by: ValproicAcid [addition]
    *** source: 19171783-Fig-3h
  *** Isg15-gene mRNA[RTPCR] is increased itpo xIfnaR2
    *** cells: U5A<IfnaR2~null> in BMS
    *** inhibited by: xIfnaR2(K399R) [substitution]
    *** source: 17923090-Fig-7f
  *** Isg15-gene mRNA[RTPCR] is increased itpo xIrf9
    *** cells: U2A<Irf9~null> in BMS
    *** inhibited by: xIrf9(K47R) [substitution]
    *** inhibited by: xIrf9(K81R) [substitution]
    *** source: 17923090-Fig-7f
  *** Isg15-gene promo-reporter[CAT] is increased itpo xIrf1
    *** cells: HEK293 in BMS
    *** source: 9566918-Fig-6c
  *** Isg15-gene promo-reporter[CAT] is increased itpo xIrf3(S396D/S398D/S402D/T404D/S405D)"5D"
    *** cells: HEK293 in BMS
    *** inhibited by: xIrf3 [substitution]
    *** inhibited by: xIrf3(S396A/S398A)"2A" [substitution]
    *** inhibited by: xIrf3(S402A/T404A/S405A)"3A" [substitution]
    *** inhibited by: xIrf3(S396A/S398A/S402A/T404A/S405A)"5A" [substitution]
    *** inhibited by: xIrf3(S385A/S386A)"J2A" [substitution]
    *** inhibited by: xIrf3(S145A/S146A)"NES" [substitution]
    *** inhibited by: xIrf3(1-407) [substitution]
    *** inhibited by: xIrf3(1-394) [substitution]
    *** inhibited by: xIrf3(1-357) [substitution]
    *** source: 9566918-Fig-6c
  *** Isg15[Ab] prot-exp[WB] is detectable
    *** cells: HEK293T in BMS "treated with Ifna for 24 hr"
    *** repressed by: Cbp [RNAi]
    *** source: 19171783-Fig-4d
  *** ISRE-reporter[Luc] is increased itpo xIkke
    *** cells: HEK293 in BMS
    *** source: 17003035-Fig-4b
  *** ISRE-reporter[Luc] is increased itpo xIrf3
    *** cells: HEK293<xTLR3> in BMS
    *** repressed by: Tnfaip3 [RNAi]
    *** source: 15661910-Fig-4g
  *** ISRE-reporter[Luc] is increased itpo xIrf3(S396D/S398D/S402D/T404D/S405D)"CA"
    *** cells: HEK293 in BMS
    *** unaffected by: xTnfaip3 [addition]
    *** source: 15661910-Fig-2b
  *** ISRE-reporter[Luc] is increased itpo xIrf7
    *** cells: HEK293 in BMS
    *** source: 18636090-Fig-3g
  *** ISRE-reporter[Luc] is increased itpo xMavs
    *** cells: HEK293 in BMS
    *** source: 18636090-Fig-3d
  *** ISRE-reporter[Luc] is increased itpo xTbk1
    *** cells: HEK293 in BMS
    *** inhibited by: xTnfaip3 [addition]
    *** source: 15661910-Fig-2a
  *** ISRE-reporter[Luc] is increased itpo xTbk1
    *** cells: HEK293 in BMS
    *** source: 17003035-Fig-4b
  *** ISRE-reporter[Luc] is increased itpo xTbk1
    *** cells: HEK293 in BMS
    *** source: 18636090-Fig-3g
  *** ISRE-reporter[Luc] is increased itpo xTbk1
    *** cells: HEK293<xTLR3> in BMS
    *** repressed by: Tnfaip3 [RNAi]
    *** source: 15661910-Fig-4f
*** Itgam--
  *** Itgam[Ab] surface-exp[FACS] is detectable
    *** cells: mBMMs in BMS
    *** does not req: Tpl2 [KO]
    *** source: 15778223-Fig-1b
  *** Itgam[Ab] surface-exp[FACS] is detectable
    *** cells: mBMMs in BMS
    *** does not req: Traf3 [KO]
    *** source: 16306936-Fig-S2a
  *** Itgax[Ab] surface-exp[FACS] is undetectable
    *** cells: mBMMs in BMS
    *** unaffected by: Traf3 [KO]
    *** source: 16306936-Fig-S2a
  *** Itgb1[Ab] copptby[WB] Apc[Ab] is undetectable
    *** cells: HELAS3 in BMS
    *** source: 20224554-Fig-5f
  *** Itgb1[Ab] copptby[WB] Dvls[Ab] is undetectable
    *** cells: HELAS3 in BMS
    *** source: 20224554-Fig-5e
  *** Itgb3-gene promo-reporter[Luc] is unchanged itpo xTbp
    *** cells: HUH7 in BMS
    *** source: 17074809-Fig-6b
  *** Itgb7-gene mRNA[RTPCR] is detectable
    *** cells: RPMI8226 in BMS
    *** reqs: Maf [RNAi]
    *** source: 19446321-Fig-6i
  *** xItsn1[tAb] snaggedby[WB] rCdc42(G15N)"NucFree"[GST] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-1
  *** xItsn1[tAb] snaggedby[WB] rRac1(G15N)"NucFree"[GST] is undetectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-1
  *** xItsn1[tAb] snaggedby[WB] rRhoa(G17A)"NucFree"[GST] is undetectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-1
  *** xItsn1[tAb] snaggedby[WB] rRhog(G15N)"NucFree"[GST] is undetectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-1
*** Jak1--
  *** Jak1[Ab] copptby[WB] Fak2[Ab] is undetectable
    *** cells: BAFB03<xIL2Rb> in BMS "IL2-deprived"
    *** unaffected by: IL2 (60 min) [stim]
    *** source: 9512511-Fig-3d
  *** Jak1[Ab] copptby[WB] Irs1[Ab] is detectable
    *** cells: hPBMCs in BMLS
    *** source: 7499365-Fig-2b
  *** Jak1[Ab] copptby[WB] Irs2[Ab] is detectable
    *** cells: hPBMCs in BMLS
    *** source: 7499365-Fig-2b
  *** Jak1[Ab] copptby[WB] Stam[Ab] is undetectable
    *** cells: ILTMAT in BMS
    *** source: 9133424-Fig-4
  *** Jak1[Ab] copptby[WB] Stam2[Ab] is undetectable
    *** cells: ILTMAT in BMS
    *** source: 10899310-Fig-2c
  *** xJak1[Ab] copptby[WB] xFak2[Ab] is undetectable
    *** cells: COS in BMS
    *** source: 9512511-Fig-3c
  *** Jak1[Ab] copptby[WB] xFes[tAb] is detectable
    *** cells: M1241 in BMS
    *** source: 11160325-Fig-2c
  *** xJak1[Ab] copptby[WB] xIL2Rb[Ab] is detectable
    *** cells: COS7 in BMS
    *** source: 9382798-Fig-5a
  *** xJak1[Ab] copptby[WB] xLifR[tAb] is detectable
    *** cells: COSM5 in BMS
    *** source: 8272873-Fig-3a
  *** xJak1[Ab] copptby[WB] xLmo4[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15677447-Fig-1b
  *** xJak1[Ab] copptby[WB] xStam2[Ab] is detectable
    *** cells: HEK293T in BMS
    *** source: 10899310-Fig-2f
  *** Jak1[Ab] snaggedby[WB] rIL2Rg[GST] is undetectable
    *** cells: U266 in BMS
    *** source: 12133952-Fig-1b
  *** Jak1[Ab] snaggedby[WB] rIL2Rg[GST] is undetectable
    *** cells: U266 in BMS
    *** source: 12133952-Fig-1c
  *** xJak1[Ab]IP Yphos[pYAb] is detectable
    *** cells: COS7 in BMS
    *** inhibited by: xJak1(K907A)"KD" [substitution]
    *** inhibited by: xJak1(Y1033F/Y1034F)"FF" [substitution]
    *** inhibited by: xJak1(Y1033F)"FY" [substitution]
    *** partially inhibited by: xJak1(Y1034F)"YF" [substitution]
    *** source: 9382798-Fig-2d
  *** xJak1[Ab]IP Yphos[pYAb] is detectable
    *** cells: SF9 in BMS
    *** unaffected by: xStat1 [addition]
    *** source: 7657660-Fig-2b
  *** xJak1[Ab]IP Yphos[pYAb] is detectable
    *** cells: U4A<xJak3> in BMS
    *** inhibited by: xJak3(mnr)"KD" [substitution]
    *** source: 10825200-Fig-6b
  *** Jak1[Ab]IP Yphos[pYAb] is unchanged itpo xBmx
    *** cells: HEK293T in BMS
    *** source: 9373245-Fig-6
  *** Jak1[phosAb] phos(Y1022/Y1023)[phosAb] is unchanged itpo xHes1
    *** cells: COS1 in BMS
    *** source: 15156153-Fig-2d
  *** xJak1[pYAb] Yphos[pYAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xSocs1 [addition]
    *** source: 9202126-Fig-3f
  *** xJak1[tAb] copptby[WB] xLmo4(21-60)"Lim1S"[GST] is detectable
    *** cells: COS1 in BMS
    *** unaffected by: xLmo4(86-125)"Lim2S" [substitution]
    *** inhibited by: xLmo4(79-165)"Lim2L" [substitution]
    *** source: 15677447-Fig-5b
  *** xJak1[tAb] copptby[WB] xSocs3[tAb] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xSocs3(Y31F) [substitution]
    *** unaffected by: xSocs3(Y204F) [substitution]
    *** unaffected by: xSocs3(Y165F/Y166F/Y167F) [substitution]
    *** unaffected by: xSocs3(Y221F) [substitution]
    *** unaffected by: xSocs3(Y204F/Y221F) [substitution]
    *** source: 11331873-Fig-1c
*** Jak2--
  *** Jak2[Ab] copptby[WB] Hes1[Ab] is detectable
    *** cells: COS1 in BMS "nuclear fraction"
    *** source: 15156153-Fig-4d
  *** Jak2[Ab] copptby[WB] Stam[Ab] is detectable
    *** cells: ILTMAT in BMS
    *** source: 9133424-Fig-4
  *** Jak2[Ab] copptby[WB] Stam2[Ab] is detectable
    *** cells: TF1 in BMS
    *** source: 10899310-Fig-2b
  *** Jak2[Ab] copptby[WB] Stat3[Ab] is increased itpo xHes1
    *** cells: COS1 in BMS
    *** source: 15156153-Fig-4d
  *** xJak2[Ab] copptby[WB] xLifR[tAb] is detectable
    *** cells: COSM5 in BMS
    *** source: 8272873-Fig-3a
  *** xJak2[Ab] copptby[WB] xSocs1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 9202126-Fig-3a
  *** xJak2[Ab] copptby[WB] xStam[Ab] is detectable
    *** cells: COS7 in BMS
    *** unaffected by: xStam(del(216-267))"DSH3" [substitution]
    *** inhibited by: xStam(del(355-388))"DIT" [substitution]
    *** inhibited by: xStam(1-370)"DY2" [substitution]
    *** source: 9133424-Fig-5b
  *** xJak2[Ab] copptby[WB] xStam2[tAb] is detectable
    *** cells: COS7 in BMS
    *** unaffected by: xStam2(del(209-256))"2DSH3" [substitution]
    *** inhibited by: xStam2(del(349-377))"2DIT" [substitution]
    *** inhibited by: xStam2(1-343)"2DY2" [substitution]
    *** source: 10899310-Fig-3d
  *** Jak2[Ab]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: HT29 in BMS "treated with IL13 for 5 min"
    *** source: 8609418-Fig-1c
  *** xJak2[Ab]IP Yphos[pYAb] is detectable
    *** cells: GAMMA2A<Jak2~null><xJak2> in BMS
    *** reqs: xJak2 [omission]
    *** inhibited by: xJak2(mnr)"KD" [substitution]
    *** source: 7537214-Fig-7b
  *** xJak2[Ab]IP Yphos[pYAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xSocs1 [addition]
    *** source: 9202126-Fig-3c
  *** Jak2[Ab]IP Yphos[pYAb] is detectable
    *** cells: KIT225 in BMS
    *** source: 7988557-Fig-1a
  *** xJak2[Ab]IP Yphos[pYAb] is detectable
    *** cells: SF9 in BMS
    *** unaffected by: xStat1 [addition]
    *** inhibited by: xJak2(L882E) [substitution]
    *** source: 7657660-Fig-2b
  *** Jak2[Ab]IP Yphos[pYAb] is detectable
    *** cells: SKBR3 in BMLS
    *** inhibited by: xJak2(del(Cterm))"KD" [addition]
    *** source: 10938266(D)
  *** Jak2[Ab]IP Yphos[pYAb] is increased itao Stat4 [KO]
    *** cells: mSpCs in BMS "activated with anti-Cd3 for 48 hr"
    *** source: 11120802-Fig-2
  *** Jak2[Ab]IP Yphos[pYAb] is increased itpo xRhoa(Q63L)"CA"
    *** cells: HEK293T in BMLS
    *** source: 11598209-Fig-4d
  *** xJak2[phosAb] phos(Y1007/Y1008)[phosAb] is increased itpo xJak1
    *** cells: COS1 in BMS
    *** source: 15156153-Fig-2d
  *** xJak2[phosAb] phos(Y1007/Y1008)[phosAb] is unchanged itpo xHes1
    *** cells: COS1 in BMS
    *** source: 15156153-Fig-2d
  *** xJak2[pYAb] Yphos[pYAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xSocs1 [addition]
    *** partially inhibited by: xSocs1(78-180)"SH2" [addition]
    *** source: 9202126-Fig-3e
  *** xJak2[pYAb] Yphos[pYAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xSocs1 [addition]
    *** source: 9202126-Fig-3d
  *** xJak2[pYAb] Yphos[pYAb] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xCish [addition]
    *** source: 9202126-Fig-3e
  *** xJak2[tAb] copptby[WB] xHes1[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 15156153-Fig-4c
  *** xJak2[tAb] copptby[WB] xHes5[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 15156153-Fig-4c
  *** xJak2[tAb] copptby[WB] xLmo4[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15677447-Fig-1b
*** Jak3--
*** Jip1--
  *** rJip1[tAb] boundby[WB] rMkk7[GST] is detectable
    *** cells: none
    *** source: 14743220-Fig-3c
  *** rJip1[tAb] boundby[WB] rPosh[GST] is detectable
    *** cells: none
    *** source: 16571722-Fig-1d
  *** xJip1[tAb] copptby[WB] xAkt1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12194869(D)
  *** xJip1[tAb] copptby[WB] xMlk3[tAb] is detectable
    *** cells: COS7<xJnk1> in BMS
    *** unaffected by: xAkt1 [addition]
    *** unaffected by: xAkt1(mnr)"KD" [addition]
    *** source: 12194869(D)
  *** xJip1[tAb] copptby[WB] xPosh[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 16571722-Fig-1b
  *** xJip1[tAb] copptby[WB] xRalGds[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 18285454-Fig-6c
  *** xJip1[tAb] copptby[WB] xRalGds[tAb] is detectable
    *** cells: COS7 in BMS
    *** unaffected by: Egf (5 min) [stim]
    *** source: 18285454-Fig-7e
  *** xJip1[tAb] copptby[WB] xRalGds[tAb] is detectable
    *** cells: COS7 in BMS
    *** unaffected by: xRalGds(mnr)"del-Nterm" [substitution]
    *** unaffected by: xRalGds(mnr)"del-Cterm" [substitution]
    *** source: 18285454-Fig-6d
  *** xJip1[tAb] copptby[WB] xRalGds[tAb] is detectable
    *** cells: COS7<xAkt1> in BMS
    *** source: 18285454-Fig-7b
  *** rJip2[tAb] boundby[WB] rPosh[GST] is detectable
    *** cells: none
    *** source: 16571722-Fig-1d
  *** xJip2[tAb] copptby[WB] xPosh[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 16571722-Fig-1b
  *** rJip3[tAb] boundby[WB] rPosh[GST] is detectable
    *** cells: none
    *** source: 16571722-Fig-1d
  *** xJip3[tAb] copptby[WB] xPosh[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 16571722-Fig-1b
  *** xJnk?[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xXiap
    *** cells: HEK293 in BMS
    *** enhanced by: SB203580 [addition]
    *** enhanced by: SB202190 [addition]
    *** source: 11356828-Fig-6c
  *** xJnk?[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xXiap
    *** cells: HEK293 in BMS
    *** partially inhibited by: xSmad4(mnr)"DN" [addition]
    *** source: 11356828-Fig-6a
  *** xJnk?[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xXiap
    *** cells: HEK293 in BMS
    *** partially inhibited by: xTak1(mnr)"DN" [addition]
    *** source: 11356828-Fig-6b
  *** xJnk?[phosAb] phos(TPY)[phosAb] is increased itpo xMavs
    *** cells: HEK293T in BMS
    *** does not req: Tradd [RNAi]
    *** source: 18439848-Fig-S10
  *** xJnk?[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMekk1
    *** cells: NotReported in BMS
    *** source: 8643568-Fig-7
  *** xJnk?[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xTifa
    *** cells: HEK293T in BMS
    *** source: 12566447-Fig-1a
  *** xJnk?[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xTraf2
    *** cells: HEK293 in BMS
    *** inhibited by: xAsk1(K709M)"KD" [addition]
    *** source: 9774977-Fig-3c
  *** xJnk?[tAb]IP IVKA(Jun)[32P-ATP] is unchanged itpo xKras(G12V)"CA"
    *** cells: HEK293 in BMLS
    *** unaffected by: xShoc2 [addition]
    *** source: 10783161-Fig-2d
  *** xJnk?[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xTraf2
    *** cells: HEK293<xMap4k5> in BMS
    *** unaffected by: xUbc13 + xUbiq [addition]
    *** inhibited by: xUbc13(C87A) + xUbiq(K63R) [addition]
    *** comment: inhibited by cotransfection of Ubc13-AS-DNA and Ubiq(K63R)
    *** source: 12591926-Fig-2a
  *** xJnk?[tAb]IP Yphos[pYAb] is increased itpo xMlk3
    *** cells: HEK293 in BMS
    *** inhibited by: xMlk3(403-462)"leucine-zipper-peptide" [addition]
    *** source: 9829970-Fig-10
  *** xJnk?[tAb]IP Yphos[pYAb] is increased itpo xMlk3
    *** cells: HEK293 in BMS
    *** inhibited by: xMlk3(del(403-462))"leucine-zipper-mutant" [substitution]
    *** source: 9829970-Fig-9
  *** rJnk1 IVKA(Jun)[32P-ATP] is increased by rMkk6
    *** cells: none
    *** source: 9384583-Fig-1b
*** Jnk1--
  *** rJnk1[32P] phos[32P-ATP] is unchanged by rMkk3
    *** cells: none
    *** source: 7839144-Fig-2a
  *** rJnk1[32P] phos[32P-ATP] is unchanged by rMkk6
    *** cells: none
    *** source: 8622669-Fig-6a
  *** rJnk1[35S] boundby[WB] rMnk1[GST] is undetectable
    *** cells: none
    *** source: 9155017-Fig-3b
  *** rJnk1[35S] boundby[WB] rMnk2[GST] is undetectable
    *** cells: none
    *** source: 9155017-Fig-3b
  *** xJnk1[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: CCL39<xJnk1> in BMS
    *** unaffected by: xDusp6(C293S) [addition]
    *** source: 9927426-Fig-2a
  *** Jnk1[Ab] phos[WBMS] is increased itpo xIkke
    *** cells: HEK293 in BMS
    *** source: 10759890-Fig-6
  *** Jnk1[Ab] snaggedby[WB] Mapkapk2[GST] is undetectable
    *** cells: HEK293 in BMS
    *** source: 10347227-Fig-6a
  *** Jnk1[Ab] snaggedby[WB] rPea15[GST] is detectable
    *** cells: CHO in BMS
    *** source: 11702783-Fig-5d
  *** xJnk1[Ab]IP IVKA(Elk1)[32P-ATP] is increased itpo xMekk1
    *** cells: NIH3T3<xJnk1> in BMLS
    *** source: 8548291-Fig-6e
  *** Jnk1[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo (xTak1 + xTab1)
    *** cells: HELA in BMS
    *** inhibited by: xTak1(T187A) [substitution]
    *** inhibited by: xTak1(K63W)"KD" [substitution]
    *** source: 15590691-Fig-1c
  *** Jnk1[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xIkke
    *** cells: HEK293 in BMS
    *** source: 10759890-Fig-6
  *** Jnk1[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xMekk4(CatDom)"CA"
    *** cells: HEK293 in BMS
    *** inhibited by: xMekk4(CatDom/K116M)"KD" [substitution]
    *** source: 9079650-Fig-3
  *** Jnk1[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xRipk1
    *** cells: HEK293 in BMS
    *** source: 16291755-Fig-3b
  *** Jnk1[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xTpl2
    *** cells: HEK293 in BMS
    *** source: 16291755-Fig-3b
  *** Jnk1[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xTpl2
    *** cells: HEK293 in BMS
    *** source: 16291755-Fig-3c
  *** Jnk1[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xTraf2
    *** cells: HEK293 in BMS
    *** source: 16291755-Fig-3c
  *** xJnk1[phosAb] phos(TPY)[phosAb] is increased itpo (xJip1 + xMlk3)
    *** cells: COS7 in BMS
    *** reqs: xMlk3 [omission]
    *** inhibited by: xAkt1 [addition]
    *** inhibited by: xAkt1(mnr)"KD" [addition]
    *** unaffected by: xAkt2 [addition]
    *** source: 12194869-Fig-1a
  *** xJnk1[phosAb] phos(TPY)[phosAb] is increased itpo xMlk3
    *** cells: COS7 in BMS
    *** enhanced by: xJip1 [addition]
    *** source: 12194869-Fig-1a
  *** xJnk1[phosAb] phos(TPY)[phosAb] is increased itpo xMlk3
    *** cells: COS7 in BMS
    *** unaffected by: xAkt1 [addition]
    *** unaffected by: xAkt1(mnr)"KD" [addition]
    *** unaffected by: xAkt2 [addition]
    *** source: 12194869-Fig-1a
  *** rJnk1[tAb] boundby[WB] rPosh[GST] is undetectable
    *** cells: none
    *** source: 16571722-Fig-1a
  *** xJnk1[tAb] copptby[WB] xGadd45b[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 14743220-Fig-1a
  *** xJnk1[tAb] copptby[WB] xJip1[tAb] is detectable
    *** cells: COS7<xMlk3> in BMS
    *** reqs: xMlk3 [omission]
    *** inhibited by: xAkt1 [addition]
    *** source: 12194869(D)
  *** xJnk1[tAb] copptby[WB] xMkk6[tAb] is undetectable
    *** cells: COS1 in BMS
    *** source: 9808624-Fig-6b
  *** xJnk1[tAb] copptby[WB] xMlk3[tAb] is detectable
    *** cells: COS7 in BMS
    *** enhanced by: xJip1 [addition]
    *** source: 12194869(D)
  *** xJnk1[tAb] copptby[WB] xMlk3[tAb] is detectable
    *** cells: COS7 in BMS
    *** unaffected by: xAkt1 [addition]
    *** unaffected by: xAkt1(mnr)"KD" [addition]
    *** source: 12194869(D)
  *** xJnk1[tAb] copptby[WB] xPosh[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 12514131-Fig-4d
  *** xJnk1[tAb] IVKA(Atf2)[32P-ATP] is increased itpo xVav1(Y142F/Y160F/Y174F)
    *** cells: JURKAT-JMCT in BMS
    *** partially inhibited by: xVav1(Y174F) [substitution]
    *** inhibited by: xVav1(WT) [substitution]
    *** source: 10669745-Fig-6b
  *** xJnk1[tAb] IVKA(Jun)[32P-ATP] is increased itpo xHpk1
    *** cells: HEK293T<xJnk1> in BMS
    *** inhibited by: xMekk1(mnr)"DN" [addition]
    *** source: 9890973-Fig-6b
  *** xJnk1[tAb] IVKA(Jun)[32P-ATP] is increased itpo xMap4k3
    *** cells: HEK293T<xJnk1> in BMS
    *** partially inhibited by: xMkk4(mnr)"DN" [addition]
    *** partially inhibited by: xMkk7(K67E)"DN" [addition]
    *** source: 9890973-Fig-5b
  *** xJnk1[tAb] IVKA(Jun)[32P-ATP] is increased itpo xMap4k4
    *** cells: HEK293T<xJnk1> in BMS
    *** inhibited by: xMap4k4(K54E) [substitution]
    *** source: 9890973-Fig-4a
  *** xJnk1[tAb] IVKA(Jun)[32P-ATP] is increased itpo xMap4k4
    *** cells: HEK293T<xJnk1> in BMS
    *** inhibited by: xMkk4(mnr)"DN" [addition]
    *** inhibited by: xMkk7(K67E)"DN" [addition]
    *** source: 9890973-Fig-5a
  *** xJnk1[tAb] IVKA(Jun)[32P-ATP] is increased itpo xMap4k4
    *** cells: HEK293T<xJnk1> in BMS
    *** inhibited by: xTak1(K63W)"DN" [addition]
    *** source: 9890973-Fig-7
  *** xJnk1[tAb] IVKA(Jun)[32P-ATP] is increased itpo xMap4k4
    *** cells: HEK293T<xJnk1> in BMS
    *** unaffected by: xMap3k12(mnr)"DN" [addition]
    *** source: 9890973-Fig-7
  *** xJnk1[tAb] snaggedby[WB] rAtf2(1-109)[GST] is detectable
    *** cells: NotReported in BMS
    *** source: 7535770-Fig-1b
  *** xJnk1[tAb]IP IVKA(Atf2)(T71)[phosAb] is increased itpo xRgl2(mnr)"CAAX"
    *** cells: NIH3T3<xInsR> in BMLS
    *** source: 12110590-Fig-5e
  *** xJnk1[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xCdc42(Q61L)"CA"
    *** cells: COS7 in BMS
    *** inhibited by: xMlk3(K144R)"DN" [addition]
    *** enhanced by: xMlk3 [addition]
    *** source: 8910292(D)
  *** xJnk1[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xCdc42(Q61L)"CA"
    *** cells: COS7 in BMS
    *** inhibited by: xPak1 [addition]
    *** source: 8910292(D)
  *** xJnk1[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xMekk1
    *** cells: COS7 in BMS
    *** inhibited by: xMkk4(K131R)"DN" [addition]
    *** source: 8910292(D)
  *** xJnk1[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xMekk1
    *** cells: COS7 in BMS
    *** unaffected by: xMlk3(K144R)"KD" [addition]
    *** source: 8910292(D)
  *** xJnk1[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xMekk1
    *** cells: HEK293T in BMS
    *** inhibited by: SP600125 [addition]
    *** source: 12972619-Fig-2f
  *** xJnk1[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xMekk1
    *** cells: NIH3T3 in BMS
    *** source: 10669751-Fig-5a
  *** xJnk1[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xRac1(Q61L)"CA"
    *** cells: COS7 in BMS
    *** inhibited by: xMlk3(K144R)"DN" [addition]
    *** source: 8910292(D)
  *** xJnk1[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xRac1(Q61L)"CA"
    *** cells: COS7 in BMS
    *** inhibited by: xPak1 [addition]
    *** source: 8910292(D)
  *** xJnk1[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xSh2d3a
    *** cells: HEK293 in BMS
    *** source: 10187783-Fig-7b
  *** xJnk1[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xTpl2
    *** cells: NIH3T3 in BMS
    *** source: 10669751-Fig-5a
  *** xJnk1[tAb]IP IVKA(Atf2)[32P-ATP] is unchanged itpo xDusp5
    *** cells: COS1<xJnk1> in BMS "stimulated with anisomycin"
    *** source: 15713638-Fig-2b
  *** xJnk1[tAb]IP IVKA(Atf2)[32P-ATP] is unchanged itpo xMek1(del(32-51)/S218E/S222D)
    *** cells: COS1 in BMS
    *** source: 8622669-Fig-2b
  *** xJnk1[tAb]IP IVKA(Atf2)[32P-ATP] is unchanged itpo xMek1(S218E/S222E)"CA"
    *** cells: NIH3T3 in BMS
    *** source: 10669751-Fig-5a
  *** xJnk1[tAb]IP IVKA(Atf2)[32P-ATP] is unchanged itpo xMek5(mnr)"CA"
    *** cells: NIH3T3 in BMS
    *** source: 10669751-Fig-5a
  *** xJnk1[tAb]IP IVKA(Atf2)[32P-ATP] is unchanged itpo xMkk3(S189E/T193E)
    *** cells: COS1 in BMS
    *** source: 8622669-Fig-2a
  *** xJnk1[tAb]IP IVKA(Atf2)[32P-ATP] is unchanged itpo xMkk6
    *** cells: NIH3T3 in BMS
    *** source: 10669751-Fig-5a
  *** xJnk1[tAb]IP IVKA(Atf2)[32P-ATP] is unchanged itpo xPak1
    *** cells: COS7 in BMS
    *** source: 8910292-Fig-1
  *** xJnk1[tAb]IP IVKA(Elk1)[32P-ATP] is increased itpo xMekk1
    *** cells: HELA<xJnk1> in BMLS
    *** source: 8846788-Fig-3b
  *** xJnk1[tAb]IP IVKA(Jun)(sitenr)[phosAb] is increased itpo xAxin1
    *** cells: HEK293T<xJnk1> in BMS
    *** inhibited by: xCsnk1a1 [addition]
    *** source: 11884395-Fig-1a
  *** xJnk1[tAb]IP IVKA(Jun)(sitenr)[phosAb] is increased itpo xAxin1
    *** cells: HEK293T<xJnk1> in BMS
    *** inhibited by: xCsnk1e [addition]
    *** partially inhibited by: xCsnk1e(K38R)"KD" [addition]
    *** source: 11884395-Fig-6a
  *** xJnk1[tAb]IP IVKA(Jun)(sitenr)[phosAb] is increased itpo xAxin1
    *** cells: HEK293T<xJnk1> in BMS
    *** inhibited by: xCsnk1e [addition]
    *** source: 11884395-Fig-1a
  *** xJnk1[tAb]IP IVKA(Jun)(sitenr)[phosAb] is increased itpo xAxin1
    *** cells: HEK293T<xJnk1> in BMS
    *** unaffected by: xCsnk2a? [addition]
    *** unaffected by: xCsnk2a?(mnr)"KD" [addition]
    *** source: 11884395-Fig-1a
  *** xJnk1[tAb]IP IVKA(Jun)(sitenr)[phosAb] is increased itpo xAxin1
    *** cells: HEK293T<xJnk1> in BMS
    *** unaffected by: xFrat1 [addition]
    *** source: 11884395-Fig-1b
  *** xJnk1[tAb]IP IVKA(Jun)(sitenr)[phosAb] is increased itpo xAxin1
    *** cells: HEK293T<xJnk1> in BMS
    *** unaffected by: xLrp5 [addition]
    *** source: 11884395-Fig-1b
  *** xJnk1[tAb]IP IVKA(Jun)(sitenr)[phosAb] is increased itpo xAxin1
    *** cells: HEK293T<xJnk1> in BMS
    *** unaffected by: xLrp6 [addition]
    *** source: 11884395-Fig-1b
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is decreased itpo xUsp6nl
    *** cells: COS7 in BMS
    *** unaffected by: xUsp6nl(R150A) [substitution]
    *** source: 11099046(D)
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is detectable
    *** cells: COS1 in BMS
    *** inhibited by: xCdc42(T17N)"DN" [addition]
    *** source: 7499279-Fig-2
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itao Sin1 [RNAi]
    *** cells: HEK293T<xMekk2> in BMS
    *** source: 15988011-Fig-5e
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo (xTak1 + xTab1)
    *** cells: HEK293<xIL1R1> in BMS
    *** unaffected by: xNik(K429A/K430A) [addition]
    *** source: 10094049-Fig-2c
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo (xTank(1-190) + xTraf2)
    *** cells: HEK293 in BMS
    *** reqs: both [omissions]
    *** unaffected by: xTbk1(K38A) [addition]
    *** source: 10581243-Fig-8a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xAsk1
    *** cells: COS1 in BMS
    *** source: 8940179-Fig-4
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xAsk1
    *** cells: COS7 in BMS
    *** source: 8974401-Fig-2a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xAsk1
    *** cells: HEK293 in BMS
    *** enhanced by: xIkbkap [addition]
    *** source: 12058026-Fig-4d
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xAsk1
    *** cells: HEK293T<xJnk1> in BMS
    *** enhanced by: xAxin1 [addition]
    *** source: 10575011-Fig-1b
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xAsk1
    *** cells: HEK293T<xJnk1> in BMS
    *** inhibited by: xAsk1(K709M) [substitution]
    *** source: 10575011-Fig-1b
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xAxin1
    *** cells: HEK293T in BMS
    *** inhibited by: xDixdc1 [addition]
    *** source: 15262978-Fig-1a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xAxin1
    *** cells: HEK293T in BMS
    *** unaffected by: xAxin1(del(210-338))"Mekk1-binding-mut" [substitution]
    *** inhibited by: xMekk1(K1274M)"DN" [addition]
    *** source: 12878610-Fig-1
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xAxin1
    *** cells: HEK293T in BMS
    *** unaffected by: xAxin1(del(679-711))"Mekk4-binding-mut" [substitution]
    *** inhibited by: xMekk4(K1317M)"DN" [addition]
    *** source: 12878610-Fig-1
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xAxin1
    *** cells: HEK293T in BMS
    *** unaffected by: xMekk2(K385M)"DN" [addition]
    *** source: 12878610-Fig-1
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xAxin1
    *** cells: HEK293T in BMS
    *** unaffected by: xMekk3(K391M)"DN" [addition]
    *** source: 12878610-Fig-1
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xAxin1
    *** cells: HEK293T<xJnk1> in BMS
    *** inhibited by: xAxin1(del(210-352))"M2" [addition]
    *** source: 10575011-Fig-5d
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xAxin1
    *** cells: HEK293T<xJnk1> in BMS
    *** inhibited by: xCsnk1e [addition]
    *** source: 11408485-Fig-3c
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xAxin1
    *** cells: HEK293T<xJnk1> in BMS
    *** inhibited by: xGsk3b [addition]
    *** bkg inhibited by: xGsk3b(Y216F) [addition]
    *** unaffected by: xGsk3b(K85M) [addition]
    *** source: 11408485-Fig-1
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xAxin1
    *** cells: HEK293T<xJnk1> in BMS
    *** inhibited by: xMekk1(K1255M) [addition]
    *** source: 10575011-Fig-2b
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xAxin1
    *** cells: HEK293T<xJnk1> in BMS
    *** partially inhibited by: xAxin1(1-600)"C1" [substitution]
    *** source: 10575011-Fig-1a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xAxin1
    *** cells: HEK293T<xJnk1> in BMS
    *** partially inhibited by: xGsk3b [addition]
    *** source: 11408485-Fig-4a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xAxin1
    *** cells: HEK293T<xJnk1> in BMS
    *** partially inhibited by: xMkk4(mnr)"DN" [addition]
    *** source: 10575011-Fig-1c
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xAxin1
    *** cells: HEK293T<xJnk1> in BMS
    *** partially inhibited by: xMkk7(mnr)"DN" [addition]
    *** source: 10575011-Fig-1c
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xAxin1
    *** cells: HEK293T<xJnk1> in BMS
    *** partially reqs: Mkk4 [RNAi]
    *** partially reqs: Mkk7 [RNAi]
    *** reqs: Mekk4 and/or Mkk7 [RNAi]
    *** source: 17187786-Fig-1c
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xAxin1
    *** cells: HEK293T<xJnk1> in BMS
    *** source: 10575011-Fig-1b
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xAxin1
    *** cells: HEK293T<xJnk1> in BMS
    *** unaffected by: xApc [addition]
    *** source: 11408485-Fig-5a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xAxin1
    *** cells: HEK293T<xJnk1> in BMS
    *** unaffected by: xAxin1(198-832)"N1" [substitution]
    *** unaffected by: xAxin1(del(354-508))"M1" [substitution]
    *** inhibited by: xAxin1(1-600)"C1" [substitution]
    *** inhibited by: xAxin1(400-832)"N2" [substitution]
    *** unaffected by: xAxin1(del(210-352))"M2" [substitution]
    *** inhibited by: xAxin1(1-746)"C2" [substitution]
    *** unaffected by: xAxin1((198-353)/(509-832))"M3" [substitution]
    *** source: 10575011-Fig-3
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xAxin1
    *** cells: HEK293T<xJnk1> in BMS
    *** unaffected by: xAxin1(del(353-437))"delGsk3-binding" [substitution]
    *** source: 11408485-Fig-1
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xAxin1
    *** cells: HEK293T<xJnk1> in BMS
    *** unaffected by: xCtnnb1(mnr)"delN" [addition]
    *** source: 11408485-Fig-4a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xAxin1
    *** cells: HEK293T<xJnk1> in BMS
    *** unaffected by: xGsk3b [addition]
    *** source: 11408485-Fig-4a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xAxin1
    *** cells: mEFs in BMS
    *** does not req: Mekk1 [KO]
    *** reqs: Mekk1 [KO] and/or Mekk4 [RNAi]
    *** source: 12878610-Fig-7a,8c
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xAxin1
    *** cells: mEFs in BMS
    *** partially reqs: Mkk4 [KO]
    *** reqs: Mkk4 and/or Mkk7 [DKO]
    *** reqs: Mkk4 [KO] and/or Mkk7 [RNAi]
    *** source: 17187786-Fig-2a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xAxin1
    *** cells: mEFs<Mekk1~null> in BMS
    *** inhibited by: xDixdc1 [addition]
    *** source: 15262978-Fig-3b
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xAxin1
    *** cells: mEFs<Mkk4~null><xJnk1> in BMS
    *** reqs: Mkk7 [RNAi]
    *** source: 17187786-Fig-2d
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xAxin1
    *** cells: mEFs<Mkk4~null><xJnk1> in BMS
    *** unaffected by: xAxin1(del(210-338))"Mekk1-binding-mut" [substitution]
    *** unaffected by: xAxin1(del(679-711))"Mekk4-binding-mut" [substitution]
    *** source: 17187786-Fig-2b
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xAxin1
    *** cells: mEFs<xJnk1> in BMS
    *** unaffected by: xAxin1(del(210-338))"Mekk1-binding-mut" [substitution]
    *** unaffected by: xAxin1(del(679-711))"Mekk4-binding-mut" [substitution]
    *** source: 17187786-Fig-2a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xAxin1(del(353-437))"delGsk3-binding"
    *** cells: HEK293T<xJnk1> in BMS
    *** unaffected by: xGsk3b [addition]
    *** unaffected by: xGsk3b(Y216F) [addition]
    *** unaffected by: xGsk3b(K85M) [addition]
    *** source: 11408485-Fig-1
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xCdc42(G12V)"CA"
    *** cells: COS1 in BMS
    *** source: 9427749-Fig-3a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xCdc42(G12V)"CA"
    *** cells: HEK293 in BMLS
    *** unaffected by: xRaf1 [addition]
    *** source: 9351825-Fig-3a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xCdc42(G12V)"CA"
    *** cells: HEK293T in BMS
    *** source: 10835426-Fig-5
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xCdc42(Q61L)
    *** cells: CHO<xJnk1> in BMLS
    *** source: 9111305-Fig-7a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xCdc42(Q61L)"CA"
    *** cells: COS in BMS
    *** inhibited by: xMekk1(K1274M) [addition]
    *** source: 9305638(D)
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xCdc42(Q61L)"CA"
    *** cells: COS in BMS
    *** inhibited by: xMekk4(K1371M) [addition]
    *** source: 9305638(D)
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xCdc42(Q61L)"CA"
    *** cells: COS in BMS
    *** unaffected by: xMekk2(K385M) [addition]
    *** source: 9305638(D)
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xCdc42(Q61L)"CA"
    *** cells: COS in BMS
    *** unaffected by: xMekk3(K391M) [addition]
    *** source: 9305638(D)
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xCdc42(Q61L)"CA"
    *** cells: HEK293 in BMS
    *** inhibited by: xMekk4(K116M)"DN" [addition]
    *** source: 9079650-Fig-6b
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xCrk
    *** cells: HEK293T in BMS
    *** inhibited by: xMekk1(mnr)"DN" [addition]
    *** inhibited by: xTak1(K63W)"KD" [addition]
    *** inhibited by: xMkk4(mnr)"DN" [addition]
    *** inhibited by: xHpk1(mnr)"DN" [addition]
    *** source: 9891069-Fig-5b
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xCrkL
    *** cells: HEK293T in BMS
    *** inhibited by: xHpk1(mnr)"DN" [addition]
    *** source: 9891069-Fig-5b
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xDvl1
    *** cells: HEK293T in BMS
    *** partially reqs: Mkk4 [RNAi]
    *** partially reqs: Mkk7 [RNAi]
    *** reqs: Mkk4 and/or Mkk7 [RNAi]
    *** source: 17187786-Fig-3a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xDvl1
    *** cells: mEFs<xJnk1> in BMS
    *** partially reqs: Mkk4 [RNAi]
    *** source: 17187786-Fig-3b
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xDvl1
    *** cells: mEFs<xJnk1> in BMS
    *** reqs: Mkk4 and/or Mkk7 [DKO]
    *** source: 17187786-Fig-3c
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xDvl2
    *** cells: HEK293T in BMS
    *** inhibited by: xDixdc1 [addition]
    *** source: 15262978-Fig-1a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xFak2
    *** cells: HEK293T in BMS
    *** enhanced by: xGrb2 [addition]
    *** unaffected by: xGrb2(del(Nterm-SH3)) [addition]
    *** partially inhibited by: xGrb2(del(Cterm-SH3)) [addition]
    *** source: 10329689-Fig-4b
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xFak2
    *** cells: HEK293T in BMS
    *** inhibited by: xFak2(Y402F) [substitution]
    *** unaffected by: xFak2(Y881F) [substitution]
    *** inhibited by: xFak2(mnr)"KD" [substitution]
    *** source: 10329689-Fig-3c
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xFak2
    *** cells: HEK293T in BMS
    *** partially inhibited by: xBcar1(del(213-514))"substrate-domain-mut" [addition]
    *** source: 10329689-Fig-6b
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xFak2
    *** cells: HEK293T in BMS
    *** partially inhibited by: xCrk(R38V)"SH2-domain-mut" [addition]
    *** source: 10329689-Fig-6b
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xFak2
    *** cells: HEK293T in BMS
    *** partially inhibited by: xSrc(mnr)"KD" [addition]
    *** source: 10329689-Fig-3d
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xFak2
    *** cells: HEK293T in BMS
    *** unaffected by: xCrk [addition]
    *** source: 10329689-Fig-4b
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xFak2
    *** cells: HEK293T in BMS
    *** unaffected by: xPxn [addition]
    *** unaffected by: xPxn(Y13F/Y187F) [addition]
    *** source: 10329689-Fig-6c
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xFak2
    *** cells: HEK293T in BMS
    *** unaffected by: xSos1(mnr)"Cterm" [addition]
    *** source: 10329689-Fig-4b
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xHpk1
    *** cells: COS7 in BMS
    *** source: 9891090-Fig-6b
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xHpk1
    *** cells: HEK293T in BMS
    *** inhibited by: xMekk1(mnr)"DN" [addition]
    *** inhibited by: xTak1(K63W)"DN" [addition]
    *** inhibited by: xMkk4(mnr)"DN" [addition]
    *** enhanced by: xCrk [addition]
    *** enhanced by: xCrkL [addition]
    *** source: 9891069-Fig-5b
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xHras(G12R)"CA"
    *** cells: NIH3T3 in BMLS
    *** source: 10803462-Fig-2
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xHras(Q61L)
    *** cells: CHO<xJnk1> in BMLS
    *** source: 9111305-Fig-7a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xHras(Q61L)
    *** cells: COS<xJnk1> in BMS
    *** source: 8137421-Fig-5a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xIkbkap
    *** cells: HELA in BMS
    *** source: 12058026-Fig-4f
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xIrak1
    *** cells: HEK293 in BMS
    *** inhibited by: xTraf6(289-522)"DN" [addition]
    *** source: 10346818-Fig-1a,1c
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMap3k12
    *** cells: COS7 in BMS
    *** source: 9891090-Fig-6a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMap4k4
    *** cells: HEK293 in BMS
    *** inhibited by: xMkk4(K129R)"DN" [addition]
    *** inhibited by: xMekk1(CatDom/K1273R)"DN" [addition]
    *** inhibited by: xMap4k4(D152N)"KD" [substitution]
    *** inhibited by: xMap4k4(Cterm) [substitution]
    *** source: 9135144-Fig-5a,6a,6b,8a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMap4k5
    *** cells: COS7 in BMS
    *** source: 9891090-Fig-6b
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMekk1
    *** cells: COS1 in BMS
    *** source: 9808624-Fig-1d
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMekk1
    *** cells: COS1 in BMS
    *** unaffected by: xSin1 [addition]
    *** source: 15988011-Fig-3a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMekk1
    *** cells: COS7 in BMS
    *** source: 9891090-Fig-6a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMekk1
    *** cells: HEK293 in BMS
    *** enhanced by: xIkbkap [addition]
    *** source: 12058026-Fig-4a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMekk1
    *** cells: HEK293 in BMS
    *** source: 9135144-Fig-5a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMekk1
    *** cells: HEK293T<xJnk1> in BMS
    *** inhibited by: xMekk1(K1255M) [substitution]
    *** inhibited by: xMekk1(mnr)"N3.1" [substitution]
    *** inhibited by: xMekk1(mnr)"N1.9" [substitution]
    *** unaffected by: xMekk1(mnr)"C" [substitution]
    *** inhibited by: xMekk1(mnr)"C-KM" [substitution]
    *** source: 10575011-Fig-2a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMekk1
    *** cells: HEK293T<xJnk1> in BMS
    *** inhibited by: xMekk1(K1255M) [substitution]
    *** source: 10575011-Fig-1b
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMekk1
    *** cells: HELA in BMS
    *** source: 9689078-Fig-3b
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMekk1
    *** cells: HELA in BMS
    *** source: 10085062-Fig-2c
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMekk1(CatDom)"CA"
    *** cells: COS1 in BMS
    *** source: 9427749-Fig-3a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMekk1(mnr)"CA"
    *** cells: NIH3T3 in BMLS
    *** source: 10803462-Fig-2
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMekk2
    *** cells: COS1 in BMS
    *** inhibited by: xMekk2(S520A) [substitution]
    *** inhibited by: xMekk2(S522A/S524A) [substitution]
    *** source: 16362041(D)
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMekk2
    *** cells: COS1 in BMS
    *** inhibited by: xSin1 [addition]
    *** source: 15988011-Fig-3a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMekk2
    *** cells: HELA in BMS
    *** source: 10085062-Fig-2c
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMekk3
    *** cells: COS7 in BMS
    *** source: 9891090-Fig-6a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMekk3
    *** cells: HELA in BMS
    *** source: 10085062-Fig-2c
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMekk4
    *** cells: COS7 in BMS
    *** source: 9305639-Fig-7b
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMekk4
    *** cells: HELA in BMS
    *** source: 9305639-Fig-7b
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMekk4(CatDom)"CA"
    *** cells: HEK293 in BMS
    *** inhibited by: xMekk4(CatDom/K116M)"KD" [substitution]
    *** source: 9079650-Fig-3
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMkk7
    *** cells: HEK293T<xJnk1> in BMS
    *** enhanced by: xAxin1 [addition]
    *** source: 10575011-Fig-1c
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMlk2
    *** cells: COS1 in BMS
    *** source: 9427749-Fig-3a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMlk3
    *** cells: COS7 in BMS
    *** source: 9891090-Fig-6a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMlk3
    *** cells: HELA in BMS
    *** source: 10085062-Fig-2c
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMras(Q71L)"CA"
    *** cells: NIH3T3 in BMLS
    *** source: 10803462-Fig-2
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xPak1(L107F)"CA"
    *** cells: COS7 in BMS
    *** source: 8805275-Fig-4a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xPak3
    *** cells: COS in BMS
    *** unaffected by: xMekk1(K1274M)"DN" [addition]
    *** unaffected by: xMekk2(K385M)"DN" [addition]
    *** unaffected by: xMekk3(K391M)"DN" [addition]
    *** unaffected by: xMekk4(K1371M)"DN" [addition]
    *** source: 9305638-Fig-8c
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xRac1(G12V)"CA"
    *** cells: COS1 in BMS
    *** source: 9427749-Fig-3a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xRac1(G12V)"CA"
    *** cells: COS7 in BMS
    *** source: 9128250-Fig-9a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xRac1(Q61L)
    *** cells: CHO<xJnk1> in BMLS
    *** source: 9111305-Fig-7a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xRac1(Q61L)"CA"
    *** cells: COS in BMS
    *** inhibited by: xMekk1(K1274M)"DN" [addition]
    *** source: 9305638-Fig-5d
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xRac1(Q61L)"CA"
    *** cells: COS in BMS
    *** inhibited by: xMekk4(K1371M)"DN" [addition]
    *** source: 9305638-Fig-5d
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xRac1(Q61L)"CA"
    *** cells: COS in BMS
    *** unaffected by: xMekk2(K385M)"DN" [addition]
    *** source: 9305638(D)
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xRac1(Q61L)"CA"
    *** cells: COS in BMS
    *** unaffected by: xMekk3(K391M)"DN" [addition]
    *** source: 9305638-Fig-5d
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xRac1(Q61L)"CA"
    *** cells: HEK293 in BMS
    *** inhibited by: xMekk4(K116M)"DN" [addition]
    *** source: 9079650-Fig-6b
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xRac2(G12V)"CA"
    *** cells: HEK293 in BMLS
    *** enhanced by: xRaf1 [addition]
    *** source: 9351825-Fig-3a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xRasGrp1
    *** cells: HEK293T in BMS
    *** source: 10835426-Fig-5
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xRipk1
    *** cells: mEFs<Ripk1~null> in BMS
    *** unaffected by: xRipk1(K45A)"KD" [substitution]
    *** source: 12776182-Fig-3c
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xSrc(Y530F)"CA"
    *** cells: HEK293 in BMS
    *** enhanced by: xTiam1 [addition]
    *** source: 12810717(D)
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xTab2
    *** cells: HEK293 in BMS
    *** inhibited by: xTak1(K63W)"DN" [addition]
    *** source: 10882101(D)
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xTab2
    *** cells: HEK293 in BMS
    *** source: 14633987-Fig-2c
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xTab3
    *** cells: HEK293 in BMS
    *** source: 14633987-Fig-2c
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xTak1
    *** cells: HEK293T<xJnk1> in BMS
    *** enhanced by: xAxin1 [addition]
    *** source: 10575011-Fig-1b
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xTak1
    *** cells: HEK293T<xJnk1> in BMS
    *** inhibited by: xTak1(K63W) [substitution]
    *** source: 10575011-Fig-1b
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xTiam1
    *** cells: COS7 in BMS
    *** partially inhibited by: xRac1(T17N)"DN" [addition]
    *** source: 9128250-Fig-9a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xTiam1
    *** cells: HEK293 in BMS
    *** enhanced by: xSrc(Y530F)"CA" [addition]
    *** source: 12810717(D)
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xTiam1
    *** cells: NIH3T3 in BMS
    *** source: 9128250-Fig-9b
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xTraf2
    *** cells: HEK293 in BMS
    *** inhibited by: xTank [addition]
    *** source: 10346818-Fig-3a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xTraf2
    *** cells: HEK293 in BMS
    *** partially inhibited by: xMekk1(K432M)"KD" [addition]
    *** source: 10346818-Fig-7c
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xTraf2
    *** cells: HEK293 in BMS
    *** source: 10346818-Fig-2b
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xTraf2
    *** cells: HEK293T<xJnk1> in BMS
    *** source: 10575011-Fig-1a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xTraf2
    *** cells: HELA in BMS
    *** partially inhibited by: xTraf2(C49A/H51A/C54A/C57A)"Ring-motif-mut" [substitution]
    *** inhibited by: xTraf2(C49A/H51A/C209A/C212A) [substitution]
    *** source: 14713952-Fig-2a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xTraf2
    *** cells: HELA in BMS
    *** unaffected by: xUbc13 [addition]
    *** source: 14713952-Fig-3c
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xTraf6
    *** cells: HEK293 in BMS
    *** unaffected by: xIrak1(del(218-507))"DN" [addition]
    *** source: 10346818-Fig-1a,1c
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is unchanged itpo xAxin1
    *** cells: mEFs<Mkk4~null><Mkk7~null><xJnk1> in BMS
    *** unaffected by: xAxin1(del(210-338))"Mekk1-binding-mut" [substitution]
    *** unaffected by: xAxin1(del(679-711))"Mekk4-binding-mut" [substitution]
    *** source: 17187786-Fig-2c
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is unchanged itpo xIkbkap
    *** cells: HEK293 in BMS
    *** source: 12058026-Fig-4a,4b,4c
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is unchanged itpo xMekk4
    *** cells: COS7 in BMS
    *** source: 9891090-Fig-6a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is unchanged itpo xMkk6
    *** cells: COS7 in BMS
    *** source: 9384583-Fig-1a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is unchanged itpo xNik
    *** cells: HELA in BMS
    *** source: 9689078-Fig-3b
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is unchanged itpo xNik
    *** cells: HELA in BMS
    *** source: 10085062-Fig-2c
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is unchanged itpo xPak1
    *** cells: COS7 in BMS
    *** source: 8805275-Fig-4a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is unchanged itpo xRaf1
    *** cells: HEK293 in BMLS
    *** source: 9351825-Fig-3a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is unchanged itpo xRasGrp2
    *** cells: HEK293T in BMS
    *** source: 10835426-Fig-5
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is unchanged itpo xRhoa(Q63L)
    *** cells: CHO<xJnk1> in BMLS
    *** source: 9111305-Fig-7a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is unchanged itpo xRhoa(Q63L)"CA"
    *** cells: HEK293 in BMLS
    *** source: 9351825-Fig-3a
  *** xJnk1[tAb]IP IVKA(Jun)[32P-ATP] is unchanged itpo xTbk1
    *** cells: HEK293 in BMS
    *** unaffected by: xTbk1(K38A) [addition]
    *** source: 10581243-Fig-8b
  *** xJnk1[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xCdc42(G12V)"CA"
    *** cells: COS7 in BMS
    *** source: 8805275-Fig-4a
  *** xJnk1[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xCdc42(Q61L)"CA"
    *** cells: COS1 in BMS
    *** source: 7499279-Fig-5
  *** xJnk1[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xPak3(F91S/G93A/P95A)"CA"
    *** cells: COS1 in BMS
    *** source: 7499279-Fig-4
  *** xJnk1[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xRac1(G12V)"CA"
    *** cells: COS7 in BMS
    *** source: 8805275-Fig-4a
  *** xJnk1[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xRhoa(G14V)"CA"
    *** cells: COS7 in BMS
    *** source: 8805275-Fig-4a
  *** xJnk1[tAb]IP IVKA(snr)[32P-ATP] is increased itpo (xDbl + xTnk2(L543F)"CA")
    *** cells: HEK293 in BMLS
    *** reqs: xDbl [omission]
    *** inhibited by: xRhoa(T19N)"DN" [addition]
    *** source: 10652228-Fig-4b
  *** xJnk1[XFP] locatedin(nucleus-cytoplasm)[IHC] is detectable
    *** cells: NIH3T3<xErk2> in BMS
    *** source: 15713638-Fig-9a
  *** xJnk1[XFP] locatedin(nucleus)[IHC] is unchanged itpo xDusp5
    *** cells: NIH3T3<xJnk1> in BMS
    *** source: 15713638-Fig-9b
*** Jnk2--
  *** rJnk2[32P] phos[32P-ATP] is unchanged by xRaf1(del(66-303))[tAb]IP
    *** cells: none
    *** comment: rMkk4 is present in the reaction mix
    *** comment: xRaf1(del(66-303)) IP is from HEK293 cells
    *** source: 10232608-Fig-5d
  *** xJnk2[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xHras(G12V)"CA"
    *** cells: mESCs in BMS
    *** inhibited by: kMekk1(1-1188)"del-kinase-domain" [addition]
    *** source: 10805784-Fig-5b
  *** xJnk2[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xMekk1
    *** cells: mESCs in BMS
    *** source: 10805784-Fig-5b
  *** Jnk2[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xMekk4(CatDom)"CA"
    *** cells: HEK293 in BMS
    *** inhibited by: xMekk4(CatDom/K116M)"KD" [substitution]
    *** source: 9079650-Fig-3
  *** xJnk2[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xRac1(Q61L)"CA"
    *** cells: mESCs in BMS
    *** unaffected by: kMekk1(1-1188)"del-kinase-domain" [addition]
    *** source: 10805784-Fig-5b
  *** rJnk2[His] IVKA(Jun)[32P-ATP] is unchanged by rMkk6
    *** cells: none
    *** source: 8663074-Fig-2
  *** xJnk2[phosAb] phos(TPY)[phosAb] is increased itpo xTnik
    *** cells: HEK293T<xJnk2> in BMS
    *** unaffected by: xRap2a [addition]
    *** source: 15342639-Fig-4a
  *** xJnk2[phosAb] phos(TPY)[phosAb] is unchanged itpo xRap2a
    *** cells: HEK293T<xJnk2> in BMS
    *** source: 15342639-Fig-4a
  *** rJnk2[tAb] boundby[WB] rPosh[GST] is undetectable
    *** cells: none
    *** source: 16571722-Fig-1a
  *** xJnk2[tAb] copptby[WB] xGadd45b[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 14743220-Fig-1a
  *** xJnk2[tAb] copptby[WB] xPosh[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 12514131-Fig-4d
  *** xJnk2[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xHras(G12V)"CA"
    *** cells: HEK293 in BMS
    *** source: 8668187-Fig-1b
  *** xJnk2[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMekk1
    *** cells: HEK293 in BMS
    *** source: 8668187-Fig-2a
  *** xJnk2[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMekk1
    *** cells: HEK293T<xJnk2> in BMS
    *** source: 10521462-Fig-5d
  *** xJnk2[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMekk4(CatDom)"CA"
    *** cells: HEK293 in BMS
    *** inhibited by: xMekk4(CatDom/K116M)"KD" [substitution]
    *** source: 9079650-Fig-3
  *** xJnk2[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xPak1
    *** cells: HEK293 in BMS
    *** source: 8668187-Fig-1b
  *** xJnk2[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xPak2
    *** cells: HEK293 in BMS
    *** source: 8668187-Fig-1b
  *** xJnk2[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xRac2(G12V)"CA"
    *** cells: HEK293 in BMS
    *** source: 8668187-Fig-1b
  *** xJnk2[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xTnik
    *** cells: HEK293T<xJnk2> in BMS
    *** source: 10521462-Fig-5a
  *** xJnk2[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xTnik
    *** cells: HEK293T<xJnk2> in BMS
    *** unaffected by: xTnik(K54R)"KD" [substitution]
    *** inhibited by: xTnik(1-306)"N1" [substitution]
    *** inhibited by: xTnik(1-1017)"N2" [substitution]
    *** unaffected by: xTnik(306-1360)"C1" [substitution]
    *** unaffected by: xTnik(1017-1360)"C2" [substitution]
    *** inhibited by: xTnik(306-1017)"M" [substitution]
    *** source: 10521462-Fig-5d
  *** xJnk2[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xTraf2
    *** cells: HEK293T<xJnk2> in BMS
    *** source: 10521462-Fig-5a
*** Jnk3--
  *** xJnk3[Ab]IP IVKA(auto)[32P-ATP] is increased itpo xMlk3
    *** cells: HEK293 in BMS
    *** bkg inhibited by: xMerlin [addition]
    *** source: 16537381-Fig-3c
  *** xJnk3[Ab]IP IVKA(Elk1)[32P-ATP] is increased itpo xMekk1
    *** cells: NIH3T3<xJnk3> in BMLS
    *** source: 8548291-Fig-6e
  *** xJnk3[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xMlk3
    *** cells: HEK293 in BMS
    *** bkg inhibited by: xMerlin [addition]
    *** source: 16537381-Fig-3c
  *** xJnk3[tAb] copptby[WB] xGadd45b[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 14743220-Fig-1a
  *** xJnk3[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xCdc42(G12V)"CA"
    *** cells: NIH3T3<xInsR> in BMS
    *** unaffected by: xRalb(S28N)"DN" [addition]
    *** source: 11046144-Fig-5b
  *** xJnk3[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xDbl(mnr)"CA"
    *** cells: COS7 in BMS
    *** source: 8999998-Fig-2c
  *** xJnk3[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xHras(G12V)"CA"
    *** cells: COS7 in BMS
    *** source: 8999998-Fig-2c
  *** xJnk3[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMap4k2
    *** cells: COS1 in BMS
    *** partially inhibited by: xMlk3(K144E)"DN" [addition]
    *** source: 9003778-Fig-7
  *** xJnk3[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMap4k2
    *** cells: HEK293T in BMS
    *** unaffected by: xMap4k5 [addition]
    *** source: 9405407-Fig-2a
  *** xJnk3[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMap4k5
    *** cells: HEK293T in BMS
    *** enhanced by: xMap4k2 [addition]
    *** source: 9405407-Fig-2a
  *** xJnk3[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMap4k5
    *** cells: HEK293T in BMS
    *** inhibited by: xMap4k5(T178A) [substitution]
    *** source: 9405407-Fig-2b
  *** xJnk3[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMap4k5
    *** cells: HEK293T in BMS
    *** inhibited by: xMekk1(K432M)"KD" [addition]
    *** source: 9405407-Fig-4e
  *** xJnk3[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMap4k5
    *** cells: HEK293T in BMS
    *** unaffected by: xAsk1(K709M)"KD" [addition]
    *** source: 9405407-Fig-4e
  *** xJnk3[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMekk1
    *** cells: COS in BMS
    *** source: 8702571-Fig-1b
  *** xJnk3[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMekk1
    *** cells: COS1 in BMS
    *** inhibited by: xMlk3(K144E)"KD" [addition]
    *** source: 9003778-Fig-1a
  *** xJnk3[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMekk1
    *** cells: NIH3T3 in BMLS
    *** source: 9006902-Fig-2a
  *** xJnk3[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMekk3
    *** cells: NIH3T3 in BMLS
    *** source: 9006902-Fig-2a
  *** xJnk3[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMlk3
    *** cells: COS in BMS
    *** source: 8702571-Fig-1a
  *** xJnk3[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMlk3
    *** cells: COS in BMS
    *** source: 8702571-Fig-1b
  *** xJnk3[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMlk3
    *** cells: COS in BMS
    *** source: 8702571-Fig-2b
  *** xJnk3[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMlk3
    *** cells: COS1 in BMS
    *** inhibited by: xMkk4(S254A/T258L)"DN" [addition]
    *** source: 9003778-Fig-1a
  *** xJnk3[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMlk3
    *** cells: HEK293 in BMS
    *** source: 10232608-Fig-4a
  *** xJnk3[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xRac1(G12V)"CA"
    *** cells: COS7 in BMS
    *** source: 8999998-Fig-2c
  *** xJnk3[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xRipk1
    *** cells: HEK293 in BMS
    *** unaffected by: xRipk1(D138N)"KD" [substitution]
    *** source: 9712898-Fig-3a
  *** xJnk3[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xSrc(mnr)"vSrc"
    *** cells: COS7 in BMS
    *** source: 8999998-Fig-2c
  *** xJnk3[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xTraf2
    *** cells: HEK293 in BMS
    *** source: 9712898-Fig-5b
  *** xJnk3[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xTraf2
    *** cells: HEK293T in BMS
    *** inhibited by: xMap4k5(T178A)"DN" [addition]
    *** source: 9405407-Fig-4c
  *** xJnk3[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xTraf2
    *** cells: HEK293T in BMS
    *** reqs: Map4k5 [AntiSense]
    *** source: 9405407-Fig-4b
  *** xJnk3[tAb]IP IVKA(Jun)[32P-ATP] is unchanged itpo xPik3c?(mnr)"CAAX"
    *** cells: COS7 in BMS
    *** source: 8999998-Fig-2c
  *** xJnk3[tAb]IP IVKA(Jun)[32P-ATP] is unchanged itpo xRaf1(del(66-303))"CA"
    *** cells: NIH3T3 in BMLS
    *** source: 9006902-Fig-2a
  *** xJnk3[tAb]IP IVKA(Jun)[32P-ATP] is unchanged itpo xRras2(G38V)"CA"
    *** cells: COS7 in BMS
    *** source: 8999998-Fig-2c
  *** xJnk3[tAb]IP phos[32Pi] is increased itpo xMekk1
    *** cells: HELA in BMS
    *** source: 9003778-Fig-1b
  *** xJnk3[tAb]IP phos[32Pi] is increased itpo xMlk3
    *** cells: HELA in BMS
    *** source: 9003778-Fig-1b
*** Jnks--
  *** Jnks[Ab] copptby[WB] xIrs1[Ab] is detectable
    *** cells: 32D<xInsR><xIrs1> in BMS
    *** inhibited by: xIrs1(L856G/L858G) [substitution]
    *** source: 12417588-Fig-4
  *** Jnks[Ab] locatedin(nucleus-cytoplasm)[IHC] is detectable
    *** cells: CCL39 in BMS
    *** unaffected by: xDusp6(C293S) [addition]
    *** source: 9927426-Fig-2a
  *** Jnks[Ab]IP IVKA(Atf2)[32P-ATP] is increased itpo xCdc42(Q61L)"CA"
    *** cells: COS7 in BMS
    *** source: 11285260-Fig-4a
  *** Jnks[Ab]IP IVKA(Atf2)[32P-ATP] is increased itpo xMlk3
    *** cells: COS7 in BMLS
    *** unaffected by: xRasGrf1 [addition]
    *** source: 11285260-Fig-4c
  *** Jnks[Ab]IP IVKA(Atf2)[32P-ATP] is increased itpo xPak1(H83L/H85L)"CA"
    *** cells: COS7 in BMLS
    *** unaffected by: xRasGrf1 [addition]
    *** source: 11285260-Fig-4c
  *** Jnks[Ab]IP IVKA(Atf2)[32P-ATP] is increased itpo xPeli3
    *** cells: HEK293 in BMS
    *** source: 12874243-Fig-4
  *** Jnks[Ab]IP IVKA(Atf2)[32P-ATP] is increased itpo xTnk2
    *** cells: COS7 in BMLS
    *** unaffected by: xRasGrf1 [addition]
    *** source: 11285260-Fig-4c
  *** Jnks[Ab]IP IVKA(Atf2)[32P-ATP] is unchanged itpo xRasGrf1
    *** cells: COS7 in BMS
    *** source: 11285260-Fig-4a
  *** Jnks[Ab]IP IVKA(Atf2)[32P-ATP] is unchanged itpo xWasp
    *** cells: COS7 in BMLS
    *** source: 11285260-Fig-4c
  *** Jnks[Ab]IP IVKA(Jun)[32P-ATP] is decreased itpo xAkt1
    *** cells: HEK293 in BMLS
    *** source: 12458207-Fig-2d
  *** Jnks[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo (xTak1 + xTab1)
    *** cells: HELA in BMS
    *** inhibited by: xTak1(K63W) [substitution]
    *** source: 11050078-Fig-1b
  *** Jnks[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xCdc42(G12V)"CA"
    *** cells: HEK293 in BMS
    *** enhanced by: xMlk3 [addition]
    *** unaffected by: xMlk3(L410P)"DN" [addition]
    *** source: 10862766(D)
  *** Jnks[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xCdc42(Q61L)
    *** cells: CHO in BMLS
    *** source: 9111305-Fig-7b
  *** Jnks[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xDbl
    *** cells: COS1 in BMS
    *** source: 8994827-Fig-5a
  *** Jnks[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xFgd1
    *** cells: COS1 in BMS
    *** source: 8994827-Fig-5a
  *** Jnks[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xHras(Q61L)
    *** cells: CHO in BMLS
    *** source: 9111305-Fig-7b
  *** Jnks[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xMekk1
    *** cells: COS1 in BMS
    *** source: 8994827-Fig-5a
  *** Jnks[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xMekk1
    *** cells: HEK293 in BMS
    *** source: 9405400-Fig-5a
  *** Jnks[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xMekk1
    *** cells: HELA in BMLS
    *** source: 8846788-Fig-2
  *** Jnks[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xMekk3
    *** cells: HEK293EBNA in BMS
    *** inhibited by: xMekk3(K391M) [substitution]
    *** inhibited by: xMekk3(S526A) [substitution]
    *** inhibited by: xMekk3(T530A) [substitution]
    *** source: 16407301(D)
  *** Jnks[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xMlk3
    *** cells: COS1 in BMS
    *** source: 9003778-Fig-5
  *** Jnks[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xMlk3
    *** cells: HEK293 in BMLS
    *** source: 12458207-Fig-2d
  *** Jnks[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xMlk3
    *** cells: HEK293 in BMS
    *** inhibited by: xMlk3(L410P)"oligo-mut" [substitution]
    *** source: 10862766(D)
  *** Jnks[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xMlk3
    *** cells: HEK293 in BMS
    *** source: 10799501(D)
  *** Jnks[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xMlk3(S674A)
    *** cells: HEK293 in BMLS
    *** unaffected by: xAkt1 [addition]
    *** source: 12458207-Fig-2d
  *** Jnks[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xRac1(Q61L)
    *** cells: CHO in BMLS
    *** source: 9111305-Fig-7b
  *** Jnks[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xRac1(Q61L)
    *** cells: COS1 in BMS
    *** source: 8994827-Fig-5a
  *** Jnks[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xRhoa(Q63L)
    *** cells: CHO in BMLS
    *** source: 9111305-Fig-7b
  *** Jnks[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xSh2d3c
    *** cells: COS7 in BMS
    *** enhanced by: xBcar1 [addition]
    *** source: 10692442-Fig-6a
  *** Jnks[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xTak1
    *** cells: HELA<xTab1> in BMS
    *** inhibited by: xTab1(1-436)"Nterm" [substitution]
    *** unaffected by: xTab1(437-504)"Cterm" [substitution]
    *** source: 10838074-Fig-5b
  *** Jnks[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xTak1
    *** cells: HELA<xTab1> in BMS
    *** unaffected by: xTak1(23-606) [substitution]
    *** partially inhibited by: xTak1(T184E/T187E) [substitution]
    *** inhibited by: xTak1(K63W) [substitution]
    *** source: 10838074-Fig-5a
  *** Jnks[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xTraf1
    *** cells: HEK293T<xTraf2> in BMS "treated with Tnf for 6 hr"
    *** source: 12370254-Fig-3a
  *** Jnks[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xTraf2
    *** cells: HEK293 in BMS
    *** inhibited by: xCiap1 [addition]
    *** source: 11907583-Fig-3d
  *** Jnks[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xTraf2
    *** cells: HEK293 in BMS
    *** inhibited by: xCiap1 [addition]
    *** unaffected by: xCiap1(mnr)"E3-activity-mut" [substitution]
    *** source: 11907583-Fig-3e
  *** Jnks[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xTraf2
    *** cells: HEK293T in BMLS
    *** source: 12370254-Fig-5b
  *** Jnks[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xTraf2
    *** cells: HEK293T in BMS "treated with Tnf for 6 hr"
    *** source: 12370254-Fig-3a
  *** Jnks[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xVav1
    *** cells: COS1 in BMS
    *** source: 8994827-Fig-5a
  *** Jnks[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xVav2
    *** cells: NIH3T3 in BMS
    *** source: 11448999-Fig-2b
  *** Jnks[Ab]IP IVKA(MBP)[32P-ATP] is increased itpo xHras(G12V)
    *** cells: NCIH82 in BMS
    *** source: 10667594-Fig-2a
  *** Jnks[Ab]IP IVKA(snr)[32P-ATP] is increased itpo xVav1
    *** cells: COS7 in BMS
    *** enhanced by: xLck [addition]
    *** enhanced by: xLck(Y505F)"CA" [addition]
    *** enhanced by: xFyn [addition]
    *** enhanced by: xFyn(1-522)"CA" [addition]
    *** enhanced by: xVav1(67-845) [substitution]
    *** source: 8990121-Fig-4b
  *** Jnks[phosAb] phos(S79)[phosAb] is increased itpo xMap4k4
    *** cells: rNCMs in BMS
    *** inhibited by: xTak1(K63W)"DN" [addition]
    *** source: 17085580(D)
  *** Jnks[phosAb] phos(TEY)[phosAb] is decreased itpo xMerlinb
    *** cells: HEI193 in BMS
    *** source: 20890305-Fig-3b
  *** Jnks[phosAb] phos(TEY)[phosAb] is decreased itpo xMerlinb
    *** cells: RT4 in BMS
    *** source: 20890305-Fig-3a
  *** Jnks[phosAb] phos(TEY)[phosAb] is decreased itpo xMerlinb
    *** cells: SKOV3 in BMS
    *** source: 20890305-Fig-3b
  *** Jnks[phosAb] phos(TEY)[phosAb] is increased itao Merlin [RNAi]
    *** cells: T29 in BMS
    *** source: 20890305-Fig-3c
  *** Jnks[phosAb] phos(TEY)[phosAb] is increased itpo xTab1
    *** cells: HEK293T<xTak1><xUbiq(K63only)> in BMS
    *** inhibited by: xTak1(K158R) [substitution]
    *** unaffected by: xTak1(K34R) [substitution]
    *** source: 20837137-Fig-2
  *** Jnks[phosAb] phos(TPY)[phosAb] is decreased itao Traf6 [KO]
    *** cells: mEFs in BMS
    *** source: 18758450-Fig-5a
  *** Jnks[phosAb] phos(TPY)[phosAb] is decreased itpo xMerlinb
    *** cells: SKOV3 in BMS
    *** reversed by: xMerlinb(S518D) [substitution]
    *** reversed by: xMerlinb(S518D) [substitution]
    *** source: 20890305-Fig-2e
  *** Jnks[phosAb] phos(TPY)[phosAb] is detectable
    *** cells: 32D<xInsR><xIrs1> in BMS
    *** inhibited by: xIrs1(L856G/L858G) [substitution]
    *** source: 12417588-Fig-5a
  *** Jnks[phosAb] phos(TPY)[phosAb] is detectable
    *** cells: CCD18CO in BMLS
    *** reqs: Mlk3 [RNAi]
    *** source: 15258589-Fig-2a
  *** Jnks[phosAb] phos(TPY)[phosAb] is detectable
    *** cells: HEK293T<xTak1> in BMS
    *** inhibited by: xTak1(K63W) [substitution]
    *** unaffected by: xTab2 [addition]
    *** unaffected by: xTab2(del(292-417))"delM" [addition]
    *** source: 20194509-Fig-S3
  *** Jnks[phosAb] phos(TPY)[phosAb] is detectable
    *** cells: HEPG2 in BMLS "plated on collagen"
    *** unaffected by: Gefitinib [cotreatment]
    *** unaffected by: PD325901 [cotreatment]
    *** unaffected by: BMS345541 [cotreatment]
    *** unaffected by: PHA818637 [cotreatment]
    *** unaffected by: ZSTK474 [cotreatment]
    *** source: 19953085-Fig-S1
  *** Jnks[phosAb] phos(TPY)[phosAb] is detectable
    *** cells: mEFs in BMS
    *** inhibited by: SB203580 [addition]
    *** source: 15304344-Fig-5a
  *** Jnks[phosAb] phos(TPY)[phosAb] is increased itpo (xTak1 + xTab1)
    *** cells: HEK293 in BMS
    *** unaffected by: xKsr2 [addition]
    *** source: 16039990-Fig-2
  *** Jnks[phosAb] phos(TPY)[phosAb] is increased itpo (xTraf2 + xUbc13 + xUbiq)
    *** cells: HEK293<xMap4k5> in BMS
    *** inhibited by: xUbiq(K63R) [substitution]
    *** unaffected by: xUbiq(K48R) [substitution]
    *** source: 12591926-Fig-2b
  *** Jnks[phosAb] phos(TPY)[phosAb] is increased itpo xCdc42(G12V)"CA"
    *** cells: HEK293 in BMS
    *** reqs: Mlk3 [RNAi]
    *** inhibited by: xMlk3(K144R)"KD" [addition]
    *** inhibited by: xMlk3(I492A/S493A)"DN" [addition]
    *** source: 16253996(D)
  *** Jnks[phosAb] phos(TPY)[phosAb] is increased itpo xCdc42(G12V)"CA"
    *** cells: HELA in BMS
    *** inhibited by: xMlk3(K144R)"KD" [addition]
    *** source: 16687404(D)
  *** Jnks[phosAb] phos(TPY)[phosAb] is increased itpo xHras(Q61L)"CA"
    *** cells: HEK293 in BMS
    *** unaffected by: xKsr2 [addition]
    *** source: 16039990-Fig-2
  *** xJnks[phosAb] phos(TPY)[phosAb] is increased itpo xMavs
    *** cells: HEK293 in BMS
    *** source: 16125763-Fig-S1a
  *** Jnks[phosAb] phos(TPY)[phosAb] is increased itpo xMekk1
    *** cells: HEK293 in BMS
    *** source: 9405400-Fig-5b
  *** Jnks[phosAb] phos(TPY)[phosAb] is increased itpo xMekk1
    *** cells: HEK293 in BMS
    *** unaffected by: xRgl3 [addition]
    *** source: 11313946-Fig-7
  *** Jnks[phosAb] phos(TPY)[phosAb] is increased itpo xMekk3
    *** cells: HEK293 in BMS
    *** partially inhibited by: xKsr2 [addition]
    *** source: 16039990-Fig-2
  *** Jnks[phosAb] phos(TPY)[phosAb] is increased itpo xMekk3
    *** cells: HELA in BMS
    *** unaffected by: xBrap [addition]
    *** source: 14724641-Fig-2a
  *** Jnks[phosAb] phos(TPY)[phosAb] is increased itpo xMekk4
    *** cells: HEK293 in BMS
    *** unaffected by: xKsr2 [addition]
    *** source: 16039990-Fig-2
  *** Jnks[phosAb] phos(TPY)[phosAb] is increased itpo xMlk3
    *** cells: HEK293 in BMS
    *** enhanced by: xPosh [addition]
    *** source: 12514131-Fig-2c
  *** Jnks[phosAb] phos(TPY)[phosAb] is increased itpo xMlk3
    *** cells: HELA in BMS
    *** inhibited by: xMlk3(K144R)"KD" [substitution]
    *** inhibited by: xMlk3(T277A) [substitution]
    *** unaffected by: xMlk3(T278A) [substitution]
    *** partially inhibited by: xMlk3(S281A) [substitution]
    *** source: 11053428-Fig-3a
  *** Jnks[phosAb] phos(TPY)[phosAb] is increased itpo xMlk3
    *** cells: HELA in BMS
    *** unaffected by: xMlk3(T277D) [substitution]
    *** unaffected by: xMlk3(S281D) [substitution]
    *** unaffected by: xMlk3(T277D/S281D) [substitution]
    *** source: 11053428-Fig-4
  *** Jnks[phosAb] phos(TPY)[phosAb] is increased itpo xPosh
    *** cells: HEK293 in BMS
    *** partially inhibited by: CEP1347 [addition]
    *** source: 16230351-Fig-3a
  *** Jnks[phosAb] phos(TPY)[phosAb] is increased itpo xPosh
    *** cells: HEK293 in BMS
    *** unaffected by: xMap3k12 [addition]
    *** inhibited by: xMap3k12(mnr)"DN" [addition]
    *** enhanced by: xMlk3 [addition]
    *** inhibited by: xMlk3(mnr)"DN" [addition]
    *** inhibited by: CEP1347 [addition]
    *** source: 12514131-Fig-2c
  *** Jnks[phosAb] phos(TPY)[phosAb] is increased itpo xRac1(Q61L)"CA"
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-5a
  *** Jnks[phosAb] phos(TPY)[phosAb] is increased itpo xRhog(Q61L)"CA"
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-5a
  *** xJnks[phosAb] phos(TPY)[phosAb] is increased itpo xRipk2
    *** cells: HEK293 in BMS
    *** source: 16125763-Fig-S1a
  *** Jnks[phosAb] phos(TPY)[phosAb] is increased itpo xSiah1
    *** cells: HEK293 in BMS
    *** partially inhibited by: CEP1347 [addition]
    *** source: 16230351-Fig-3a
  *** Jnks[phosAb] phos(TPY)[phosAb] is increased itpo xTak1
    *** cells: HEK293T<xTab1> in BMS
    *** unaffected by: xTak1(T178A) [substitution]
    *** unaffected by: xTak1(T184A) [substitution]
    *** inhibited by: xTak1(T178A/T184A) [substitution]
    *** enhanced by: xTak1(T178E/T184E) [substitution]
    *** source: 18617512-Fig-3b
  *** Jnks[phosAb] phos(TPY)[phosAb] is increased itpo xTLR4
    *** cells: HEK293 in BMS
    *** inhibited by: xMyd88(del(1-151))"DN" [addition]
    *** unaffected by: xTraf6(del(1-288))"DN" [addition]
    *** source: 9625770-Fig-4a
  *** Jnks[phosAb] phos(TPY)[phosAb] is increased itpo xTraf6
    *** cells: HEK293 in BMS
    *** source: 9625770-Fig-4a
  *** Jnks[phosAb] phos(TPY)[phosAb] is unchanged itpo xNemo
    *** cells: HEK293T in BMS
    *** source: 10755617(D)
  *** Jnks[phosAb] phos(TPY)[phosAb] is unchanged itpo xRin1(Q78L)
    *** cells: PC6 in BMLS
    *** source: 16157584-Fig-1d
*** Jun--
  *** Jun-gene mRNA[RTPCR] is decreased itao Tnik [RNAi]
    *** cells: DLD1 in BMS
    *** source: 20530691-Fig-5
  *** Jun-gene mRNA[RTPCR] is decreased itao Tnik [RNAi]
    *** cells: HCT116 in BMS
    *** source: 20530691-Fig-5
  *** Jun-gene mRNA[RTPCR] is detectable
    *** cells: HELA in BMS
    *** does not req: Arrb1 [RNAi]
    *** unaffected by: xArrb1 [addition]
    *** unaffected by: xArrb1(Q394L) [addition]
    *** source: 16325578-Fig-2a
  *** Jun-gene mRNA[RTPCR] is detectable
    *** cells: HELA in BMS
    *** does not req: Arrb1 [RNAi]
    *** unaffected by: xArrb1 [addition]
    *** unaffected by: xArrb1(Q394L) [addition]
    *** source: 16325578-Fig-6a
  *** Jun-gene mRNA[RTPCR] is detectable
    *** cells: HELA in BMS
    *** does not req: Arrb2 [RNAi]
    *** unaffected by: xArrb2 [addition]
    *** source: 16325578-Fig-2a
  *** Jun-gene mRNA[RTPCR] is unchanged itpo xArrb1
    *** cells: mEFs<Arrb1~null><Arrb2~null> in BMS
    *** source: 16325578-Fig-2b
  *** Jun-gene mRNA[RTPCR] is unchanged itpo xArrb2
    *** cells: mEFs<Arrb1~null><Arrb2~null> in BMS
    *** source: 16325578-Fig-2b
  *** Jun-gene mRNA[RTPCR] is unchanged itpo xEp300
    *** cells: HELA in BMS
    *** unaffected by: xEp300(mnr)"DN" [substitution]
    *** source: 16325578-Fig-6a
  *** Jun-gene mRNA[RTPCR] is unchanged itpo xEp300
    *** cells: mEFs<Arrb1~null><Arrb2~null> in BMS
    *** unaffected by: xEp300(mnr)"DN" [substitution]
    *** source: 16325578-Fig-6b
  *** Jun-gene promo-reporter[CAT] is increased itpo xAsk1
    *** cells: H1299<Tp53~null> in BMS
    *** source: 10581258-Fig-2b
  *** Jun-gene promo-reporter[CAT] is increased itpo xAsk1
    *** cells: MCF7 in BMS
    *** source: 10581258-Fig-1b
  *** Jun-gene promo-reporter[CAT] is increased itpo xJnk1
    *** cells: H1299<Tp53~null> in BMS
    *** source: 10581258-Fig-2b
  *** Jun-gene promo-reporter[CAT] is increased itpo xJnk1
    *** cells: MCF7 in BMS
    *** source: 10581258-Fig-1b
  *** Jun-gene promo-reporter[CAT] is increased itpo xMekk1
    *** cells: H1299<Tp53~null> in BMS
    *** source: 10581258-Fig-2b
  *** Jun-gene promo-reporter[CAT] is increased itpo xMekk1
    *** cells: MCF7 in BMS
    *** source: 10581258-Fig-1b
  *** Jun-gene promo-reporter[CAT] is increased itpo xMkk4
    *** cells: H1299<Tp53~null> in BMS
    *** source: 10581258-Fig-2b
  *** Jun-gene promo-reporter[CAT] is increased itpo xMkk4
    *** cells: MCF7 in BMS
    *** source: 10581258-Fig-1b
  *** Jun-gene promo-reporter[CAT] is increased itpo xP38?
    *** cells: H1299<Tp53~null> in BMS
    *** source: 10581258-Fig-2b
  *** Jun-gene promo-reporter[CAT] is increased itpo xP38?
    *** cells: MCF7 in BMS
    *** source: 10581258-Fig-1b
  *** Jun-gene promo-reporter[CAT] is unchanged itpo xErk2
    *** cells: H1299<Tp53~null> in BMS
    *** source: 10581258-Fig-2b
  *** Jun-gene promo-reporter[CAT] is unchanged itpo xErk2
    *** cells: MCF7 in BMS
    *** source: 10581258-Fig-1b
  *** Jun-gene promo-reporter[CAT] is unchanged itpo xMek1
    *** cells: H1299<Tp53~null> in BMS
    *** source: 10581258-Fig-2b
  *** Jun-gene promo-reporter[CAT] is unchanged itpo xMek1
    *** cells: MCF7 in BMS
    *** source: 10581258-Fig-1b
  *** Jun-gene promo-reporter[CAT] is unchanged itpo xRaf1(mnr)"BXB"
    *** cells: H1299<Tp53~null> in BMS
    *** source: 10581258-Fig-2b
  *** Jun-gene promo-reporter[CAT] is unchanged itpo xRaf1(mnr)"BXB"
    *** cells: MCF7 in BMS
    *** source: 10581258-Fig-1b
  *** Jun-gene promo-reporter[Luc] is increased itpo xMekk1
    *** cells: NIH3T3 in BMS
    *** inhibited by: xJip1 [addition]
    *** source: 10669751-Fig-1b,3a
  *** Jun-gene promo-reporter[Luc] is increased itpo xMkk6(S207E/T211E)"CA"
    *** cells: NotReported in BMS
    *** source: 9069290-Fig-4a
  *** Jun-gene promo-reporter[Luc] is increased itpo xTbp
    *** cells: HUH7 in BMS
    *** source: 17074809-Fig-6b
  *** Jun-gene promo-reporter[Luc] is increased itpo xTbp
    *** cells: mEFs in BMS
    *** repressed by: Jnk1 [KO]
    *** reqs: Jnk2 [KO]
    *** source: 17074809-Fig-6a
  *** Jun-gene promo-reporter[Luc] is increased itpo xTpl2
    *** cells: NIH3T3 in BMS
    *** inhibited by: xTpl2(K162R)"KD" [substitution]
    *** inhibited by: xJip1 [addition]
    *** source: 10669751-Fig-1b,3a
  *** Jun-gene promo-reporter[Luc] is unchanged itpo xRaf1(mnr)"CAAX"
    *** cells: NIH3T3 in BMS
    *** source: 10669751-Fig-1b
  *** rJun(1-79) phos[32P-ATP] is increased by rP38a{act}
    *** cells: none
    *** source: 9155018-Fig-8a
  *** rJun(1-79)[32P] phos[32P-ATP] is unchanged by rP38a{act}
    *** cells: none
    *** source: 11948414-Fig-2a
  *** rJun(1-93)[32P] phos[32P-ATP] is unchanged by rP38a
    *** cells: none
    *** source: 8663524-Fig-3
  *** rJun(1-93)[32P] phos[32P-ATP] is unchanged by rP38b
    *** cells: none
    *** source: 8663524-Fig-3
  *** xJun(1-194)[Gal4-DBD] Gal4-reporter[CAT] is increased itpo xHras(G12V)
    *** cells: 1BR in BMS
    *** inhibited by: xHras(G12V/C186S) [substitution]
    *** source: 7816602-Fig-2
  *** xJun(1-233)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xHras(G12V)
    *** cells: NCIH82 in BMS
    *** bkg inhibited by: xJun(1-233/S63A/S73A) [substitution]
    *** source: 10667594-Fig-5b
  *** rJun(235-331)[35S] boundby[WB] rSmad3[GST] is detectable
    *** cells: none
    *** inhibited by: rJun(235-331) [substitution]
    *** source: 9732876-Fig-2f
  *** rJun(235-331)[35S] boundby[WB] rSmad4[GST] is undetectable
    *** cells: none
    *** unaffected by: rJun(235-331) [substitution]
    *** source: 9732876-Fig-2f
  *** xJun(S63D/S73D)[His]IP oligo-binding[EMSA] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xJun [substitution]
    *** inhibited by: xJun(S91A/S93A) [substitution]
    *** source: 7744008-Fig-3
  *** xJun(TAD)[Gal4-DBD] Gal4-reporter[Luc] is detectable
    *** cells: HEK293T<xMekk2> in BMS
    *** inhibited by: xSin1 [addition]
    *** source: 15988011-Fig-5f
  *** xJun(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo (xCrkL + xRapGef1)
    *** cells: PC12 in BMLS
    *** source: 9560161-Fig-2b
  *** xJun(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xCdc42(Q61L)
    *** cells: CHO in BMLS
    *** bkg inhibited by: xMkk4(mnr)"DN" [addition]
    *** source: 9111305-Fig-8d
  *** xJun(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xCdc42(Q61L)
    *** cells: CHO in BMLS
    *** source: 9111305-Fig-7b
  *** xJun(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xCdc42(Q61L)
    *** cells: CHO in BMLS
    *** unaffected by: SB203580 [addition]
    *** source: 9111305-Fig-8d
  *** xJun(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xHras(Q61L)
    *** cells: CHO in BMLS
    *** inhibited by: xMkk4(mnr)"DN" [addition]
    *** source: 9111305-Fig-8e
  *** xJun(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMekk1
    *** cells: COS1 in BMS
    *** unaffected by: xSin1 [addition]
    *** source: 15988011-Fig-3d
  *** xJun(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMekk2
    *** cells: COS1 in BMS
    *** inhibited by: xSin1 [addition]
    *** source: 15988011-Fig-3d
  *** xJun(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMkk6(S207E/T211E)"CA"
    *** cells: CHO in BMS
    *** source: 8663524-Fig-9
  *** xJun(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMyd88
    *** cells: HEK293 in BMS
    *** source: 11544529-Fig-2b
  *** xJun(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xP38a
    *** cells: CHO in BMS
    *** unaffected by: xMkk3(S189E/T193E)"CA" [addition]
    *** enhanced by: xMkk6(S207E/T211E)"CA" [addition]
    *** source: 8663524-Fig-9
  *** xJun(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xP38b
    *** cells: CHO in BMS
    *** unaffected by: xMkk3(S189E/T193E)"CA" [addition]
    *** enhanced by: xMkk6(S207E/T211E)"CA" [addition]
    *** source: 8663524-Fig-9
  *** xJun(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xPeli2
    *** cells: HEK293 in BMS
    *** source: 12804775-Fig-2a
  *** xJun(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xPeli3
    *** cells: HEK293 in BMS
    *** source: 12874243-Fig-3
  *** xJun(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xRac1(Q61L)
    *** cells: CHO in BMLS
    *** source: 9111305-Fig-7b
  *** xJun(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xRhoa(Q63L)
    *** cells: CHO in BMLS
    *** source: 9111305-Fig-7b
  *** xJun(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xTirap
    *** cells: HEK293 in BMS
    *** source: 11544529-Fig-2b
  *** xJun(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xVav1(Y142F/Y160F/Y174F)
    *** cells: JURKAT<Pten~null> in BMS
    *** partially inhibited by: xVav1(Y174F) [substitution]
    *** inhibited by: xVav1(WT) [substitution]
    *** source: 10669745-Fig-6b
  *** xJun(TAD)[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xMkk3(S189E/T193E)"CA"
    *** cells: CHO in BMS
    *** source: 8663524-Fig-9
  *** xJun(TAD)[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xPeli1
    *** cells: HEK293 in BMS
    *** source: 12804775-Fig-2b
  *** rJun[32P] phos[32P-ATP] is unchanged by rP38a
    *** cells: none
    *** source: 7535770-Fig-1a
  *** rJun[32P] phos[32P-ATP] is unchanged by xP38a{act}[tAb]IP
    *** cells: none
    *** IPfrom: COS1 in BMS "treated with UV for tnr"
    *** source: 8622669-Fig-4e
  *** rJun[35S] boundby[WB] rEts2[GST] is detectable
    *** cells: none
    *** enhanced by: xFos [addition]
    *** source: 9334186-Fig-1a
  *** rJun[35S] boundby[WB] rSmad3[GST] is detectable
    *** cells: none
    *** inhibited by: rSmad3(1-144)"N-term" [substitution]
    *** enhanced by: rSmad3(1-210)"LN-term" [substitution]
    *** inhibited by: rSmad3(210-425)"C-term" [substitution]
    *** inhibited by: rSmad3(144-425)"LC-term" [substitution]
    *** source: 9732876-Fig-2e
  *** rJun[35S] boundby[WB] rSmad3[GST] is detectable
    *** cells: none
    *** source: 9732876-Fig-2g
  *** rJun[35S] boundby[WB] rSmad4[GST] is undetectable
    *** cells: none
    *** source: 9732876-Fig-2e
  *** Jun[Ab] boundto(A2m-gene)[ChIP] is detectable
    *** cells: H35 in BMS
    *** unaffected by: Dexamethasone [addition]
    *** unaffected by: IL6 (30 min) [stim]
    *** source: 14522952-Fig-4b
  *** Jun[Ab] boundto(ProTnf-gene)[ChIP] is detectable
    *** cells: CHANG in BMS
    *** source: 17451682-Fig-5d
  *** Jun[Ab] oligo-binding[EMSA] is increased itpo xPld2
    *** cells: HEK293T<xEgfR> in BMLS
    *** enhanced by: xArf4(Q71L)"CA" [addition]
    *** source: 12446727-Fig-6b
  *** Jun[Ab] prot-exp[WB] is decreased itao Jnk1 [KO]
    *** cells: mEFs in BMS
    *** source: 17074809-Fig-5a
  *** Jun[Ab] prot-exp[WB] is decreased itao Tbp [AntiSense]
    *** cells: mEFs in BMS
    *** source: 17074809-Fig-5a
  *** Jun[Ab] prot-exp[WB] is increased itao Jnk2 [KO]
    *** cells: mEFs in BMS
    *** source: 17074809-Fig-5a
  *** Jun[Ab] prot-exp[WB] is increased itpo xHras(G12V)
    *** cells: NCIH82 in BMS
    *** source: 10667594-Fig-5b
  *** Jun[Ab] prot-exp[WB] is increased itpo xHras(Q61L)
    *** cells: mEFs in BMS
    *** source: 17974977-Fig-3d
  *** Jun[Ab] prot-exp[WB] is increased itpo xTbp
    *** cells: mEFs in BMS
    *** source: 17074809-Fig-5a
  *** xJun[Ab] snaggedby[WB] oligo[biotin] is detectable
    *** cells: COS1<xTgfbR1(mnr)"CA"><xTgfbR2> in BMS
    *** oligo: AP1 5-CGCTTGATGAGTCAGCCGGAA-3
    *** source: 9732876-Fig-3d
  *** xJun[Ab] snaggedby[WB] rPin1[GST] is detectable
    *** cells: HELA<xJun> in BMS
    *** enhanced by: xHras(Q61L) [addition]
    *** unaffected by: xHras(S17N) [addition]
    *** source: 11432833-Fig-4c
  *** xJun[Ab] snaggedby[WB] rPin1[GST] is detectable
    *** cells: HELA<xJun> in BMS
    *** enhanced by: xJnk?(mnr)"CA" [addition]
    *** source: 11432833-Fig-4d
  *** xJun[Ab] snaggedby[WB] rPin1[GST] is detectable
    *** cells: HELA<xJun> in BMS
    *** inhibited by: xJun(S63A/S73A) [substitution]
    *** source: 11432833-Fig-4e
  *** xJun[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xIrak4
    *** cells: HEK293 in BMS
    *** source: 11960013-Fig-3b
  *** xJun[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMek1(del(32-51)/S218E/S222D)
    *** cells: CHO in BMS
    *** source: 8622669-Fig-4c
  *** xJun[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMekk1
    *** cells: HEK293 in BMS
    *** source: 11960013-Fig-3b
  *** xJun[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMekk1(380-672)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-3b
  *** xJun[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xRhoa(Q63L)"CA"
    *** cells: HEK293T in BMLS
    *** inhibited by: xRhoa(Q63L/F39L) [substitution]
    *** partially inhibited by: xRhoa(Q63L/F39E) [substitution]
    *** unaffected by: xRhoa(Q63L/D45Q) [substitution]
    *** partially inhibited by: xRhoa(Q63L/V35D) [substitution]
    *** source: 11598209-Fig-9b
  *** xJun[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo (xMkk3(S189E/T193E) + xP38a)
    *** cells: CHO in BMS
    *** source: 8622669-Fig-4c
  *** xJun[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xMek1(del(32-51)/S218E/S222E)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-3b
  *** Jun[phosAb] phos(S63)[phosAb] is decreased itpo xPik3c2b
    *** cells: A431 in BMLS
    *** source: 16775008-Fig-4c
  *** Jun[phosAb] phos(S63)[phosAb] is detectable
    *** cells: HEPG2 in BMLS "plated on collagen"
    *** unaffected by: Gefitinib [cotreatment]
    *** partially inhibited by: PD325901 [cotreatment]
    *** unaffected by: BMS345541 [cotreatment]
    *** unaffected by: PHA818637 [cotreatment]
    *** unaffected by: ZSTK474 [cotreatment]
    *** source: 19953085-Fig-S1
  *** Jun[phosAb] phos(S63)[phosAb] is increased itpo xRgl2(mnr)"CAAX"
    *** cells: NIH3T3<xInsR> in BMS
    *** inhibited by: xRgl2(CAAX/R328E)"Gef-mut" [substitution]
    *** source: 11046144-Fig-2b
  *** Jun[phosAb] phos(S63/S73)[phosAb] is decreased itpo xPosh
    *** cells: HEK293<xMlk3> in BMS
    *** reversed by: xPosh(W489A) [substitution]
    *** source: 14504284(D)
  *** xJun[phosAb] phos(S63/S73)[phosAb] is increased itpo xHras(Q61L)
    *** cells: HELA<xJun> in BMS
    *** inhibited by: xHras(S17N) [substitution]
    *** source: 11432833-Fig-4a
  *** xJun[phosAb] phos(S63/S73)[phosAb] is increased itpo xJnk?(mnr)"CA"
    *** cells: HELA<xJun> in BMS
    *** source: 11432833-Fig-4a
  *** Jun[phosAb] phos(S63/S73)[phosAb] is increased itpo xMlk3
    *** cells: HEK293 in BMS
    *** enhanced by: xCdc42(G12V)"CA" [addition]
    *** source: 16687404(D)
  *** Jun[phosAb] phos(S63/S73)[phosAb] is increased itpo xMlk3
    *** cells: MCF7 in BMS
    *** partially inhibited by: SP600125 [addition]
    *** partially inhibited by: CEP11004 [addition]
    *** source: 16687404(D)
  *** Jun[phosAb] phos(S63/S73)[phosAb] is increased itpo xMlk3
    *** cells: MCF7 in BMS
    *** source: 15001580-Fig-1
  *** Jun[phosAb] phos(S73)[phosAb] is increased itpo xHras(G12V)"CA"
    *** cells: NIH3T3<xInsR> in BMS
    *** source: 11046144-Fig-1c
  *** Jun[phosAb] phos(S73)[phosAb] is increased itpo xNemo
    *** cells: HEK293T in BMS
    *** source: 10755617(D)
  *** Jun[phosAb] phos(S73)[phosAb] is increased itpo xRgl2(mnr)"CAAX"
    *** cells: NIH3T3<xInsR> in BMS
    *** inhibited by: xRgl2(CAAX/R328E)"Gef-mut" [substitution]
    *** source: 11046144-Fig-2b
  *** xJun[phosAb] phos(sitenr)[phosAb] is detectable
    *** cells: COS7 in BMLS
    *** inhibited by: xJun(del(TAD))"Tam67" [substitution]
    *** unaffected by: xJun(del(DBD))"DBM3" [substitution]
    *** source: 12738796-Fig-5b
  *** xJun[phosAb] phos(sitenr)[phosAb] is increased itpo xMlk3
    *** cells: COS7 in BMLS
    *** unaffected by: xJun(mnr)"DBM3" [substitution]
    *** source: 12738796-Fig-5b
  *** Jun[phosAb] phos(sitenr)[phosAb] is increased itpo xRala
    *** cells: 3Y1<xEgfR> in BMLS
    *** inhibited by: xRala(S28N) [substitution]
    *** inhibited by: xRala(del(1-11)) [substitution]
    *** inhibited by: xRala(D49N) [substitution]
    *** inhibited by: xRala(S17N) [substitution]
    *** source: 10611224-Fig-3a
  *** Jun[phosAb] phos(sitenr)[phosAb] is increased itpo xTraf6
    *** cells: HEK293 in BMS
    *** does not req: Sqstm1 [AntiSense]
    *** source: 10747026-Fig-3
  *** Jun[phosAb] phos(sitenr)[phosAb] is increased itpo xTraf6
    *** cells: HEK293 in BMS
    *** unaffected by: xPkci(mnr)"DN" [substitution]
    *** source: 10747026-Fig-3
  *** rJun[RE] oligo-binding[EMSA] is detectable
    *** cells: none
    *** oligo: AP1 5-CGCTTGATGAGTCAGCCGGAA-3
    *** source: 9732876-Fig-3c
  *** xJun[tAb] boundto(Cdk1-gene)[ChIP] is detectable
    *** cells: HCT116<xJun> in BMS "treated with Anisomycin"
    *** unaffected by: xJun(T63A/T73A/T91A/T93A) [substitution]
    *** source: 16007074-Fig-2c
  *** xJun[tAb] boundto(Myc-gene)[ChIP] is undetectable
    *** cells: HCT116<xJun> in BMS "treated with Anisomycin"
    *** unaffected by: xJun(T63A/T73A/T91A/T93A) [substitution]
    *** source: 16007074-Fig-2c
  *** xJun[tAb] copptby[WB] xFos[tAb] is detectable
    *** cells: F9 in BMS
    *** partially inhibited by: rSmad3(1-210)"LN-term" [addition]
    *** source: 9732876-Fig-2c
  *** xJun[tAb] oligo-binding[EMSA] is detectable
    *** cells: COS1<xTgfbR1(mnr)"CA"><xTgfbR2><xSmad3><xSmad4><xFos> in BMS
    *** oligo: AP1 5-CGCTTGATGAGTCAGCCGGAA-3
    *** source: 9732876-Fig-3f
  *** xJun[XFP] locatedin(nucleus)[IHC] is detectable
    *** cells: COS1<xAtf2(T69A/T71A)> in BMS
    *** unaffected by: xAtf2(T69D/T71D) [substitution]
    *** unaffected by: xJun(S63A/S73A) [substitution]
    *** comment: xJun is dimerized with xAtf2(T69A/T71A) [BiFC]
    *** source: 16511568-Fig-S5C
  *** xJun[XFP] locatedin(nucleus)[IHC] is detectable
    *** cells: COS1<xAtf2> in BMS
    *** comment: xJun is dimerized with xAtf2 [BiFC]
    *** source: 16511568-Fig-1a
  *** xJun[XFP] locatedin(nucleus)[IHC] is detectable
    *** cells: COS1<xFos> in BMS
    *** comment: xJun is dimerized with xFos [BiFC]
    *** source: 16511568-Fig-1a
  *** xJun[XFP] locatedin(subnuclear-bodies)[IHC] is detectable
    *** cells: COS1 in BMS
    *** comment: xJun is a dimer [BiFC]
    *** source: 16511568-Fig-1a
  *** xJun[XFP] locatedin(subnuclear-bodies)[IHC] is detectable
    *** cells: COS1 in BMS
    *** source: 16511568-Fig-1a
*** Junb--
  *** Junb-gene mRNA[RTPCR] is detectable
    *** cells: mSpBCs in BMS "treated with anti-Cd40 (24 hr)"
    *** partially inhibited by: kMekk1(1-1188)"del-kinase-domain" [addition]
    *** source: 17143273-Fig-6c
*** Jup--
  *** Jup[Ab] colocwith[IHC] Ptprf[Ab] is detectable
    *** cells: NBTII in BMS
    *** comment: colocalization occurs in the adherens junctions
    *** source: 10187801-Fig-4
  *** Jup[Ab] copptby[WB] Cdh1[Ab] is detectable
    *** cells: MCF7 in BMS
    *** unaffected by: Egf (30 min) [stim]
    *** source: 10187801-Fig-5a,5b
  *** Jup[Ab] copptby[WB] Cdh1[Ab] is detectable
    *** cells: MCF7 in BMS
    *** unaffected by: Egf (30 min) [stim]
    *** source: 10187801-Fig-5b
  *** Jup[Ab] copptby[WB] Cdh1[Ab] is detectable
    *** cells: NBTII in BMS
    *** unaffected by: Pervanadate [addition]
    *** unaffected by: Egf (30 min) [stim]
    *** unaffected by: Fgf1 + Heparin (30 min) [stim]
    *** unaffected by: Orthovanadate [addition]
    *** source: 10187801-Fig-2
  *** Jup[Ab] copptby[WB] Ptprf[Ab] is detectable
    *** cells: MCF7 in BMS
    *** unaffected by: Egf (30 min) [stim]
    *** source: 10187801-Fig-5b
  *** Kat2a[Ab] copptby[WB] Max[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 10611234-Fig-3a
  *** Kat2a[Ab] copptby[WB] Max[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 12660246-Fig-1a
  *** Kat2a[Ab] copptby[WB] Myc[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 10611234-Fig-3a
  *** Kat2a[Ab] copptby[WB] xMyc[tAb] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xMyc(111-439) [substitution]
    *** source: 12660246-Fig-1b
  *** Kat2a[Ab] copptby[WB] xMyc[tAb] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xTrrap(1899-2401) [addition]
    *** source: 12660246-Fig-5d
  *** Kat2a[Ab] copptby[WB] xMyc[tAb] is detectable
    *** cells: HEK293<xMyc> in BMS
    *** inhibited by: xMyc(del(100-116)) [substitution]
    *** source: 10611234-Fig-3a
  *** Kat2a[Ab] snaggedby[WB] rMyc(1-262)[tAb] is detectable
    *** cells: HELA in BMS "nuclear-extract"
    *** source: 10611234-Fig-2a
  *** Kat2a[Ab] snaggedby[WB] rMyc[GST] is detectable
    *** cells: HELA in BMS "nuclear-extracts"
    *** source: 12660246-Fig-2a
  *** Kat2a[Ab] snaggedby[WB] rMyc[GST] is undetectable
    *** cells: HELA in BMS "nuclear-extracts"
    *** source: 12660246-Fig-2a
  *** Kif23[Ab] copptby[WB] xRacGap1[tAb] is detectable
    *** cells: HELA<xRacGap1> in BMS
    *** unaffected by: xRacGap1(del(125-285)) [substitution]
    *** unaffected by: xRacGap1(del(205-285)) [substitution]
    *** unaffected by: xRacGap1(del(125-204)) [substitution]
    *** unaffected by: xRacGap1(del(190-285)) [substitution]
    *** unaffected by: xRacGap1(del(125-160)/del(205-285)) [substitution]
    *** unaffected by: xRacGap1(del(125-171)/del(205-285)) [substitution]
    *** unaffected by: xRacGap1(del(125-164)/del(205-285)) [substitution]
    *** unaffected by: xRacGap1(del(165-204)) [substitution]
    *** unaffected by: xRacGap1(K178A/K179A/R180A) [substitution]
    *** unaffected by: xRacGap1(K182A/R183A/R184A) [substitution]
    *** unaffected by: xRacGap1(K199A/K200A) [substitution]
    *** unaffected by: xRacGap1(K182A/R183A/R184A/K199A/K200A) [substitution]
    *** source: 19158271-Fig-1b
  *** xKifap3[tAb] copptby[WB] xMlk2[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 9427749-Fig-7a
  *** xKit((544-975)/D814V)"CA"[pYAb] Yphos[pYAb] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xSocs1 [addition]
    *** source: 9202126-Fig-3f
*** rKpna?--
  *** rKpna?[Fluor] nuc-import[IVnucImport] is detectable
    *** cells: none
    *** comment: requires cytosol or addition of Kpnb1
    *** source: 12917407-Fig-5a
  *** rKpna?[Fluor] nuc-import[IVnucImport] is detectable
    *** cells: none
    *** inhibited by: rRan(Q69L){GTP} [addition]
    *** comment: requires cytosol
    *** source: 12917407-Fig-4
*** Kpna1--
  *** Kpna1[Ab] snaggedby[WB] rNfkb1[GST] is undetectable
    *** cells: A549 in BMS
    *** source: 15677444-Fig-1c
  *** Kpna1[Ab] snaggedby[WB] rRela[GST] is undetectable
    *** cells: A549 in BMS
    *** source: 15677444-Fig-1c
*** Kpna3--
  *** Kpna3[Ab] snaggedby[WB] rNfkb1[GST] is detectable
    *** cells: A549 in BMS
    *** source: 15677444-Fig-1c
  *** Kpna3[Ab] snaggedby[WB] rRela[GST] is detectable
    *** cells: A549 in BMS
    *** source: 15677444-Fig-1c
  *** rKras GDP-dissociation[3H-GDP] is unchanged by rRalGds
    *** cells: none
    *** source: 8094051-Fig-5
*** rKras--
  *** xKras(G12V)"CA"[tAb]IP IVKA(Mek1,Erk2,MBP)[32P-ATP] is increased itpo (xMras(H81L)"CA" + xShoc2)
    *** cells: HEK293T<xRaf1> in BMS
    *** partially reqs: xShoc2 [omission]
    *** partially reqs: xMras(H81L)"CA" [omission]
    *** source: 16630891-Fig-6c
  *** Kras[Ab] GTP-association[BDPD] is increased itpo (xTnk2 + xCdc42(G12V)"CA")
    *** cells: HEK293<xRasGrf1> in BMLS
    *** source: 10882715-Fig-6
  *** Kras[Ab] GTP-association[BDPD] is increased itpo xTnk2(L543F)"CA"
    *** cells: HEK293<xRasGrf1> in BMLS
    *** source: 10882715-Fig-6
  *** Kras[Ab] GTP-association[BDPD] is unchanged itpo xRasGrf1
    *** cells: HEK293 in BMLS
    *** source: 10882715-Fig-6
  *** xKras[tAb] copptby[WB] xRaf1[tAb] is detectable
    *** cells: HEK293 in BMLS
    *** enhanced by: xShoc2 [addition]
    *** unaffected by: xShoc2(C260Y)"DN" [addition]
    *** unaffected by: xShoc2(E457K)"DN" [addition]
    *** source: 10783161-Fig-4a,4b
  *** xKras[tAb]IP GTP-association[TLC] is unchanged itpo xRasGrf1
    *** cells: NIH3T3 in BMLS
    *** comment: xKras-splice-variant(2) (aka 4B, 2B, PO1118-2) is used
    *** source: 9430727-Fig-1
*** Ksr1--
  *** xKsr1(540-873)"mCterm"[tAb] oligomerization[2TagPpt] is decreased itpo xBrap
    *** cells: HEK293<xKsr1> in BMS
    *** source: 18332145-Fig-1d
  *** xKsr1[Ab] phos[WBMS-PPase] is increased itpo xBrap
    *** cells: HEK293 in BMS
    *** source: 14724641-Fig-4b,4c
  *** Ksr1[Ab] snaggedby[WB] rRaf1[GST] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 9115393-Fig-4a
  *** xKsr1[phosAb] phos(S392)[phosAb] is unchanged itpo xBrap
    *** cells: HEK293 in BMS
    *** inhibited by: xKsr1(I397A/V401A)"Mark3-BS-mut" [substitution]
    *** source: 14724641-Fig-4b
  *** xKsr1[phosAb] phos(S404)[phosAb] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xKsr1(I397A/V401A)"Mark3-BS-mut" [substitution]
    *** unaffected by: xBrap [addition]
    *** source: 14724641-Fig-4b
  *** xKsr1[tAb] copptby[WB] Erks[Ab] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xKsr1(C857Y) [substitution]
    *** source: 10409742-Fig-2d
  *** xKsr1[tAb] copptby[WB] Mek12s[Ab] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xKsr1(C857Y) [substitution]
    *** source: 10409742-Fig-1d,2d
  *** xKsr1[tAb] copptby[WB] xBrap[tAb] is detectable
    *** cells: HEK293<xBrap> in BMS
    *** source: 18332145-Fig-4d
  *** xKsr1[tAb] copptby[WB] xBrap[tAb] is detectable
    *** cells: HEK293<xKsr1><xBrap> in BMS
    *** source: 18332145-Fig-1b
  *** xKsr1[tAb] copptby[WB] xMek1[tAb] is detectable
    *** cells: mEFs<Ksr1~null><xKsr1><xMek1> in BMS
    *** inhibited by: xMek1(del(270-307))"dPRS" [substitution]
    *** unaffected by: xMek1(L274S) [substitution]
    *** unaffected by: xMek1(F275A) [substitution]
    *** unaffected by: xMek1(D303A) [substitution]
    *** inhibited by: xMek1(M308A/I310A) [substitution]
    *** source: 19541618-Fig-1c
  *** xKsr1[tAb] copptby[WB] xMek2[tAb] is detectable
    *** cells: mEFs<Ksr1~null><xKsr1><xMek2> in BMS
    *** inhibited by: xMek2(M316A/I318A) [substitution]
    *** source: 19541618-Fig-1c
  *** xKsr1[tAb] copptby[WB] xRaf1[tAb] is decreased itpo xBrap
    *** cells: HEK293<xRaf1><xKsr1> in BMS
    *** unaffected by: xRaf1(1-330)"Nterm" [substitution]
    *** source: 18332145-Fig-4b
  *** xKsr1[tAb] copptby[WB] Ywhas[Ab] is detectable
    *** cells: HEK293T in BMS
    *** source: 10409742-Fig-1d
  *** xKsr1[tAb] oligomerization[2TagPpt] is detectable
    *** cells: HEK293<xKsr1> in BMS
    *** source: 18332145-Fig-1c
  *** xKsr1[tAb]IP phos(S309)[HPLC-PAA-ED] is decreased itpo xHras(G12V)"CA"
    *** cells: HEK293 in BMS
    *** source: 9858547-Fig-1
  *** xKsr1[tAb]IP phos(S309)[HPLC-PAA-ED] is detectable
    *** cells: HEK293 in BMS
    *** source: 9858547-Fig-1
  *** xKsr1[tAb]IP phos(S309)[HPLC-PAA-ED] is detectable
    *** cells: NIH3T3 in BMLS
    *** unaffected by: Pdgf (5 min) [stim]
    *** source: 12932319-Fig-3a
  *** xKsr1[tAb]IP phos(S404)[HPLC-PAA-ED] is decreased itpo xHras(G12V)"CA"
    *** cells: HEK293 in BMS
    *** source: 9858547-Fig-1
  *** xKsr1[tAb]IP phos(S404)[HPLC-PAA-ED] is detectable
    *** cells: HEK293 in BMS
    *** source: 9858547-Fig-1
  *** xKsr1[tAb]IP phos(S404)[HPLC-PAA-ED] is detectable
    *** cells: NIH3T3 in BMLS
    *** source: 12932319-Fig-3a
  *** xKsr1[tAb]IP phos(S455)[HPLC-PAA-ED] is increased itpo xHras(G12V)"CA"
    *** cells: HEK293 in BMS
    *** source: 9858547-Fig-1
  *** xKsr1[tAb]IP phos(T272)[HPLC-PAA-ED] is increased itpo xHras(G12V)"CA"
    *** cells: HEK293 in BMS
    *** source: 9858547-Fig-1
  *** xKsr1[tAb]IP phos(T286)[HPLC-PAA-ED] is increased itpo xHras(G12V)"CA"
    *** cells: HEK293 in BMS
    *** source: 9858547-Fig-1
  *** xKsr1[tAb]IP STphos[pSTAb] is detectable
    *** cells: mEFs<Ksr1~null><xKsr1><xMek1> in BMLS
    *** partially inhibited by: xKsr1(mnr)"AxAp" [substitution]
    *** source: 19541618-Fig-4b
  *** Ku70[Ab] copptby[WB] xTip60[tAb] is detectable
    *** cells: HELA<xTip60> in BMS
    *** source: 16603769-Fig-S2a
  *** Ku70[Ab] prot-exp[WB] is detectable
    *** cells: XRS6Y<Ku80~null><xKu80> in BMS
    *** reqs: xKu80 [omission]
    *** unaffected by: xKu80(1-718)"delC" [substitution]
    *** source: 15758953-Fig-4c
  *** Ku70[Ab] prot-exp[WB] is unchanged itao Mre11 [RNAi]
    *** cells: HT1080<xAtm> in BMS
    *** source: 20026654-Fig-S1d
  *** Ku70[Ab] prot-exp[WB] is unchanged itao Nbs1 [RNAi]
    *** cells: HT1080<xAtm> in BMS
    *** source: 20026654-Fig-S1d
  *** Ku70[Ab] prot-exp[WB] is unchanged itao Rad50 [RNAi]
    *** cells: HT1080<xAtm> in BMS
    *** source: 20026654-Fig-S1d
  *** Ku70[Ab] snaggedby[WB] sH2ax(123-143){phos(S140)}[GST] is undetectable
    *** cells: HELA in BMS "nuclear-extracts"
    *** unaffected by: sH2ax(123-143) [substitution]
    *** source: 16377563-Fig-1b
  *** Ku80[Ab] copptby[WB] Atrip[Ab] is undetectable
    *** cells: HELA in BMS "nuclear-extract"
    *** comment: IP was performed in the presence of linear dsDNA
    *** source: 15758953-Fig-S4b
  *** Ku80[Ab] copptby[WB] Nbs1[Ab] is undetectable
    *** cells: HELA in BMS "nuclear-extract"
    *** comment: IP was performed in the presence of linear dsDNA
    *** source: 15758953-Fig-S4b
  *** xKu80[Ab] copptby[WB] Prkdc[Ab] is detectable
    *** cells: XRS6Y<Ku80~null><xKu80> in BMS
    *** inhibited by: xKu80(1-718)"delC" [substitution]
    *** inhibited by: xKu80(E720A/E721A) [substitution]
    *** inhibited by: xKu80(D726A/D727A) [substitution]
    *** source: 15758953-Fig-4b
  *** xKu80[Ab] snaggedby[WB] dsDNA[biotin] is detectable
    *** cells: XRS6Y<Ku80~null><xKu80> in BMS
    *** unaffected by: xKu80(1-718)"delC" [substitution]
    *** source: 15758953-Fig-4d
*** Lamtor1--
  *** xLamtor1[tAb]IP boundby[WB] xAtp6V0c[GST]IP is detectable
    *** cells: none
    *** IPfrom: HEK293T<xLamtor1> in BMS
    *** IPfrom: HEK293T<xAtp6V0c> in BMS
    *** source: 22053050-Fig-3d
  *** xLamtor1[tAb]IP boundby[WB] xAtp6V1d[GST]IP is detectable
    *** cells: none
    *** IPfrom: HEK293T<xLamtor1> in BMS
    *** IPfrom: HEK293T<xAtp6V1d> in BMS
    *** source: 22053050-Fig-3d
*** Lamtor2--
  *** xLamtor2[tAb]IP boundby[WB] xAtp6V0c[GST]IP is undetectable
    *** cells: none
    *** IPfrom: HEK293T<xLamtor2> in BMS
    *** IPfrom: HEK293T<xAtp6V0c> in BMS
    *** source: 22053050-Fig-3d
  *** xLamtor2[tAb]IP boundby[WB] xAtp6V1d[GST]IP is undetectable
    *** cells: none
    *** IPfrom: HEK293T<xLamtor2> in BMS
    *** IPfrom: HEK293T<xAtp6V1d> in BMS
    *** source: 22053050-Fig-3d
*** Lamtor3--
  *** xLamtor3[tAb] copptby[WB] xMek1[tAb] is detectable
    *** cells: CCL39<xWdr83><xMek1><xLamtor3> in BMS
    *** inhibited by: xMek1(del(270-307))"dPRS" [substitution]
    *** source: 15118098-Fig-3c
*** Lck--
  *** xLck(Y505F)[Ab] copptby[WB] xIL2Rb[Ab] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xCish [addition]
    *** source: 10514520-Fig-6c
  *** xLck[35S] copptby[WB] xIL2Rb[Ab] is detectable
    *** cells: COS7 in BMS
    *** unaffected by: xIL2Rb(1-404)"H-mutant" [substitution]
    *** inhibited by: xIL2Rb(del(338-409))"A-mutant" [substitution]
    *** unaffected by: xIL2Rb(del(292-349))"S-mutant" [substitution]
    *** inhibited by: xIL2Rb(1-281)"ST-mutant" [substitution]
    *** source: 2047859-Fig-4c
  *** Lck[Ab] copptby[WB] IL2Ra[Ab] is undetectable
    *** cells: YT in BMS
    *** source: 2047859-Fig-1
  *** Lck[Ab] copptby[WB] IL2Rb[Ab] is detectable
    *** cells: YT in BMS
    *** source: 2047859-Fig-1
  *** Lck[Ab] copptby[WB] Stam[Ab] is undetectable
    *** cells: ILTMAT in BMS
    *** source: 9133424-Fig-4
  *** Lck[Ab] copptby[WB] Stam2[Ab] is undetectable
    *** cells: ILTMAT in BMS
    *** source: 10899310-Fig-2e
  *** xLck[Ab] copptby[WB] xIL2Rb[Ab] is detectable
    *** cells: COS7 in BMS
    *** enhanced by: xLck(del(12-33))"LM1" [substitution]
    *** enhanced by: xLck(del(35-148))"LM2" [substitution]
    *** enhanced by: xLck(del(128-231))"LM3" [substitution]
    *** source: 2047859-Fig-5b
  *** xLck[Ab] copptby[WB] xIL2Rb[Ab] is detectable
    *** cells: COS7 in BMS
    *** inhibited by: xLck(1-232)"LM4" [substitution]
    *** unaffected by: xLck(1-369)"LM5" [substitution]
    *** source: 2047859-Fig-5c
  *** xLck[Ab] copptby[WB] xIL2Rb[Ab] is detectable
    *** cells: COS7 in BMS
    *** partially inhibited by: xIL2Rb(1-404)"H-mutant" [substitution]
    *** inhibited by: xIL2Rb(del(338-409))"A-mutant" [substitution]
    *** partially inhibited by: xIL2Rb(del(292-349))"S-mutant" [substitution]
    *** inhibited by: xIL2Rb(1-281)"ST-mutant" [substitution]
    *** source: 2047859-Fig-4a
  *** xLck[Ab] copptby[WB] xIL2Rb[Ab] is detectable
    *** cells: COS7 in BMS
    *** source: 2047859-Fig-2
  *** Lck[Ab] prot-exp[WB] is decreased itpo xRhoa(Q63L)"CA"
    *** cells: HEK293T in BMLS
    *** source: 11598209-Fig-5d
  *** xLck[Ab]IP IVKA(auto)[32P-ATP] is increased itpo xJak3
    *** cells: NIH3T3<xIL2Ra><xIL2Rb><xIL2Rg><Jak3~null><Lck~null><xLck(mnr)"CA"> in BMS
    *** source: 10825200-Fig-3a
  *** xLck[tAb]IP Yphos[pYAb] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xLck(Y505F) [substitution]
    *** source: 10514520-Fig-6a
  *** Lef1-reporter[Luc] is decreased itpo xAxin1
    *** cells: COS1<xWnt1><xLef1> in BMS
    *** source: 10644691-Fig-2d
  *** Lef1-reporter[Luc] is increased itpo (xLef1 + xPpm1a)
    *** cells: COS1 in BMS
    *** partially inhibited by: xPpm1a(R195K) [substitution]
    *** source: 10644691-Fig-2a
  *** Lef1-reporter[Luc] is increased itpo (xLef1 + xPpm1a)
    *** cells: COS1<xDvl3> in BMS
    *** partially inhibited by: xPpm1a(R195K) [substitution]
    *** source: 10644691-Fig-2c
  *** Lef1-reporter[Luc] is increased itpo (xLef1 + xPpm1a)
    *** cells: COS1<xWnt1> in BMS
    *** partially inhibited by: xPpm1a(R195K) [substitution]
    *** source: 10644691-Fig-2c
  *** Lef1-reporter[Luc] is increased itpo xCsnk1e
    *** cells: HEK293 in BMS
    *** enhanced by: xCsnk1e(S323A/T325A/T334A/T337A/S368A/S405A/T407A/S408A)"MM2" [substitution]
    *** source: 14722104-Fig-5a
  *** Lef1-reporter[Luc] is increased itpo xCsnk1e
    *** cells: HEK293T in BMS
    *** inhibited by: xCsnk1e(K38R)"KD" [substitution]
    *** source: 11884395-Fig-6d
  *** Lef1-reporter[Luc] is increased itpo xCtnnb1
    *** cells: NIH3T3 in BMS
    *** unaffected by: xLrp5(1-1372) [addition]
    *** unaffected by: xLrp5(1-300) [addition]
    *** source: 11336703-Fig-1e
  *** Lef1-reporter[Luc] is increased itpo xDvl1
    *** cells: NIH3T3 in BMS
    *** unaffected by: xLrp5(1-1372) [addition]
    *** unaffected by: xLrp5(1-300) [addition]
    *** source: 11336703-Fig-1e
  *** Lef1-reporter[Luc] is increased itpo xLef1
    *** cells: COS1 in BMS
    *** enhanced by: xPpm1a [addition]
    *** source: 10644691-Fig-2a
  *** Lef1-reporter[Luc] is increased itpo xLef1
    *** cells: COS1<xCtnnb1> in BMS
    *** enhanced by: xPpm1a [addition]
    *** unaffected by: xPpm1a(R195K) [addition]
    *** source: 10644691-Fig-2b
  *** Lef1-reporter[Luc] is increased itpo xLef1
    *** cells: COS1<xCtnnb1> in BMS
    *** unaffected by: xGsk3b [addition]
    *** source: 10644691-Fig-2b
  *** Lef1-reporter[Luc] is increased itpo xLef1
    *** cells: COS1<xDvl3> in BMS
    *** enhanced by: xPpm1a [addition]
    *** source: 10644691-Fig-2c
  *** Lef1-reporter[Luc] is increased itpo xLef1
    *** cells: COS1<xPpm1a> in BMS
    *** source: 10644691-Fig-2d
  *** Lef1-reporter[Luc] is increased itpo xLef1
    *** cells: COS1<xWnt1> in BMS
    *** enhanced by: xPpm1a [addition]
    *** source: 10644691-Fig-2c
  *** Lef1-reporter[Luc] is increased itpo xLrp5(1203-1615)"C1"
    *** cells: NIH3T3 in BMS
    *** source: 11336703-Fig-2d
  *** Lef1-reporter[Luc] is increased itpo xLrp5(1370-1615)"C2"
    *** cells: NIH3T3 in BMS
    *** source: 11336703-Fig-2d
  *** Lef1-reporter[Luc] is increased itpo xPpm1a
    *** cells: COS1 in BMS
    *** enhanced by: xLef1 [addition]
    *** source: 10644691-Fig-2a
  *** Lef1-reporter[Luc] is increased itpo xPpm1a
    *** cells: COS1 in BMS
    *** unaffected by: xPpm1a(R195K) [substitution]
    *** source: 10644691-Fig-2a
  *** Lef1-reporter[Luc] is increased itpo xPpm1a
    *** cells: COS1<xAxin1><xLef1> in BMS
    *** source: 10644691-Fig-2d
  *** Lef1-reporter[Luc] is increased itpo xPpm1a
    *** cells: COS1<xWnt1><xLef1><xAxin1> in BMS
    *** inhibited by: xPpm1a(R195K) [substitution]
    *** source: 10644691-Fig-2d
  *** Lef1[Ab] copptby[WB] Ctnnb1[Ab] is detectable
    *** cells: HACAT in BMS
    *** reqs: Smad7 [RNAi]
    *** source: 15684397-Fig-2a
  *** Lef1[Ab] copptby[WB] Ctnnb1[Ab] is detectable
    *** cells: PC3U in BMS
    *** reqs: Smad7 [RNAi]
    *** source: 15684397-Fig-2a
  *** xLef1[Ab] copptby[WB] xSmad7(204-426)"Cterm"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** partially inhibited by: xSmad7(WT) [substitution]
    *** source: 15684397-Fig-1b
  *** xLef1[Ab] phos[WBMS-PPase] is increased itpo xNlk
    *** cells: HEK293<xTcf7l2> in BMS
    *** enhanced by: xTak1 + xTab1 [addition]
    *** source: 10391247-Fig-4b
  *** xLef1[Ab] phos[WBMS-PPase] is increased itpo xNlk
    *** cells: HEK293<xTcf7l2> in BMS
    *** inhibited by: xNlk(K155M) [substitution]
    *** source: 10391247-Fig-4b
  *** xLef1[tAb] copptby[WB] xNlk[tAb] is detectable
    *** cells: HEK293<xLef1><xNlk> in BMS
    *** unaffected by: xCtnnb1 [addition]
    *** source: 12556497-Fig-1
  *** xLef1[tAb] copptby[WB] xNlk[tAb] is detectable
    *** cells: HEK293<xLef1><xNlk> in BMS
    *** unaffected by: xLef1(62-399)"delN" [substitution]
    *** unaffected by: xLef1(1-299)"delC" [substitution]
    *** source: 12556497-Fig-3b
  *** xLef1[tAb] copptby[WB] xNlk[tAb] is detectable
    *** cells: HEK293<xLef1><xNlk> in BMS
    *** unaffected by: xLef1(mnr)"delN" [addition]
    *** source: 12556497-Fig-1
  *** xLef1[tAb] copptby[WB] xNlk[tAb] is detectable
    *** cells: HEK293<xLef1><xNlk> in BMS
    *** unaffected by: xLef1(T155A/S166A) [substitution]
    *** source: 12556497-Fig-5a
  *** xLef1[tAb] copptby[WB] xNlk[tAb] is detectable
    *** cells: HEK293<xLef1><xNlk> in BMS
    *** unaffected by: xNlk(K155M)"KD" [substitution]
    *** source: 12556497-Fig-3b
  *** xLef1[tAb] phos[WBMS] is increased itpo xNlk
    *** cells: HEK293<xLef1> in BMS
    *** inhibited by: xLef1(T155A/S166A) [substitution]
    *** comment: xLef1(T155A/S166A) has a different staining pattern than xLef1
    *** source: 12556497-Fig-4d
  *** xLef1[tAb] phos[WBMS] is increased itpo xNlk
    *** cells: HEK293<xLef1> in BMS
    *** inhibited by: xNlk(K155M)"KD" [substitution]
    *** source: 12556497-Fig-4d
  *** xLef1[tAb]IP ubiq[WBMS] is increased itpo (xNlk + xTab2 + xTak1)
    *** cells: HEK293T<xLef1> in BMS
    *** inhibited by: xTab2(del(292-417))"delM" [substitution]
    *** inhibited by: xTab2(417-693)"C3" [substitution]
    *** source: 20194509-Fig-5d
  *** xLef1[tAb]IP ubiq[WBMS] is increased itpo (xNlk + xTab2 + xTak1)
    *** cells: HEK293T<xLef1> in BMS
    *** reqs: xNlk [omission]
    *** reqs: xTab2 [omission]
    *** reqs: xTak1 [omission]
    *** inhibited by: xNlk(mnr)"KD" [substitution]
    *** source: 20194509-Fig-5c
  *** xLepR[Ab] copptby[WB] xSnx6[tAb] is detectable
    *** cells: COS7 in BMLS
    *** source: 11279102(D)
  *** xLgp2[tAb] snaggedby[WB] PolyC[agarose] is undetectable
    *** cells: HEK293 in BMS
    *** source: 16210631-Fig-6b
  *** xLgp2[tAb] snaggedby[WB] PolyIC[agarose] is detectable
    *** cells: HEK293 in BMS
    *** source: 16210631-Fig-6b
  *** xLgp2[tAb] snaggedby[WB] PolyIC[agarose] is detectable
    *** cells: HEK293T in BMS
    *** source: 16116171-Fig-3f
  *** LifR[Ab]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: EW1 in BMLS
    *** source: 8272873-Fig-1a
  *** xLime1[tAb] copptby[WB] xMekk2[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 11073940-Fig-5c,5d
  *** xLime1[tAb] copptby[WB] xMekk3[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 11073940-Fig-5c,5d
  *** Limk1[Ab] copptby[WB] Pxn[Ab] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 15023529-Fig-3b
  *** Limk1[Ab] copptby[WB] Pxn[Ab] is detectable
    *** cells: OLF442 in BMS
    *** source: 15023529-Fig-3b
  *** xLimk1[tAb]IP IVKA(Cfl1)[32P-ATP] is increased itpo xCdc42(G12V)"CA"
    *** cells: COS7 in BMS
    *** unaffected by: Y27632 [addition]
    *** source: 11340065-Fig-1a
  *** xLimk1[tAb]IP IVKA(Cfl1)[32P-ATP] is increased itpo xCdc42bpa
    *** cells: COS7 in BMS
    *** source: 11340065-Fig-2c
  *** Limk1[tAb]IP IVKA(Cfl1)[32P-ATP] is increased itpo xRock1(mnr)"CA"
    *** cells: COS7<xRac1(T17N)> in BMS
    *** source: 10436159-Fig-2b
  *** xLimk1[tAb]IP IVKA(Cfl1)[32P-ATP] is unchanged itpo xRock1
    *** cells: COS7 in BMS
    *** source: 11340065-Fig-2c
  *** xLimk2[tAb]IP IVKA(Cofilin)[32P-ATP] is increased itpo xCdc42(G12V)"CA"
    *** cells: COS7 in BMS
    *** partially inhibited by: Y27632 [addition]
    *** source: 11340065-Fig-1b
  *** xLimk2[tAb]IP IVKA(Cofilin)[32P-ATP] is increased itpo xCdc42bpa
    *** cells: COS7 in BMS
    *** source: 11340065-Fig-2c
  *** xLimk2[tAb]IP IVKA(Cofilin)[32P-ATP] is increased itpo xRock1
    *** cells: COS7 in BMS
    *** source: 11340065-Fig-2c
*** Lkb1--
  *** rLkb1(D194A)[32P] phos[32P-ATP] is unchanged by rAkt1(mnr)
    *** cells: none
    *** source: 11297520-Fig-1a
  *** Lkb1[Ab]IP IVKA(LKBtide)[32P-ATP] is detectable
    *** cells: mEFs in BMS
    *** reqs: Tak1 [KO]
    *** source: 17085580(D)
  *** xLkb1[Ab]IP IVKA(LKBtide)[32P-ATP] is increased itpo (xStrada + xCab39)
    *** cells: mEFs in BMS
    *** reqs: Tak1 [KO]
    *** source: 17085580(D)
  *** xLkb1[Ab]IP IVKA(LKBtide)[32P-ATP] is increased itpo (xStrada + xCab39)
    *** cells: rNCMs in BMS
    *** inhibited by: xTak1(K63W)"KD" [addition]
    *** source: 17085580(D)
  *** xLkb1[GST]IP IVKA(auto)[32P-ATP] is unchanged itpo xCab39L
    *** cells: HEK293 in BMS
    *** source: 14517248-Fig-9
  *** xLkb1[GST]IP IVKA(auto)[32P-ATP] is unchanged itpo xStradb
    *** cells: HEK293 in BMS
    *** source: 14517248-Fig-9
  *** xLkb1[GST]IP IVKA(MBP)(T65)[phosAb] is unchanged itpo xCab39L
    *** cells: HEK293 in BMS
    *** source: 14517248-Fig-9
  *** xLkb1[GST]IP IVKA(MBP)(T65)[phosAb] is unchanged itpo xStradb
    *** cells: HEK293 in BMS
    *** source: 14517248-Fig-9
  *** xLkb1[GST]IP IVKA(MBP)[32P-ATP] is unchanged itpo xCab39L
    *** cells: HEK293 in BMS
    *** source: 14517248-Fig-9
  *** xLkb1[GST]IP IVKA(MBP)[32P-ATP] is unchanged itpo xStradb
    *** cells: HEK293 in BMS
    *** source: 14517248-Fig-9
  *** Lkb1[phosAb] phos(S428)[phosAb] is decreased irt U0126 (4 hr)
    *** cells: A375 in BMLS "Low-Glucose"
    *** source: 19274086-Fig-3a
  *** Lkb1[phosAb] phos(S428)[phosAb] is decreased irt U0126 (4 hr)
    *** cells: SKMEL28 in BMLS "Low-Glucose"
    *** source: 19274086-Fig-3a
  *** xLkb1[phosAb] phos(S428)[phosAb] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xLkb1(S428A) [substitution]
    *** inhibited by: xLkb1(D194A)"KD" [substitution]
    *** inhibited by: xLkb1(C430A)"prenyl-site-mut" [substitution]
    *** source: 11297520-Fig-12c
  *** Lkb1[phosAb] phos(S428)[phosAb] is detectable
    *** cells: SKMEL28 in BMS
    *** comment: bands are shifted up in response to serum-depletion
    *** source: 19274086-Fig-2b
  *** Lkb1[phosAb] phos(S428)[phosAb] is unchanged irt Glucose-deprivation (4 hr)
    *** cells: A375 in BMLS
    *** source: 19274086-Fig-3a
  *** Lkb1[phosAb] phos(S428)[phosAb] is undetectable
    *** cells: 3731E in BMLS "Low-Glucose"
    *** unaffected by: U0126 [addition]
    *** source: 19274086-Fig-3a
  *** Lkb1[phosAb] phos(S428)[phosAb] is undetectable
    *** cells: MEWO in BMS
    *** unaffected by: Serum-depletion (tnr) [stress]
    *** source: 19274086-Fig-2b
  *** xLkb1[tAb] copptby[WB] xBraf(V600E)[tAb] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xBraf(WT) [substitution]
    *** source: 19187764-Fig-4h
  *** xLkb1[tAb] copptby[WB] xCtnnb1[tAb] is undetectable
    *** cells: COS in BMS
    *** source: 11741830-Fig-2a
  *** xLkb1[tAb] copptby[WB] xErk?[tAb] is increased itpo xBraf(V600E)
    *** cells: HEK293 in BMS
    *** inhibited by: xBraf(WT) [substitution]
    *** source: 19187764-Fig-4i
  *** xLkb1[tAb] copptby[WB] xSmad4[tAb] is undetectable
    *** cells: COS in BMS
    *** source: 11741830-Fig-2a
  *** xLkb1[tAb] copptby[WB] xStk11ip[tAb] is detectable
    *** cells: COS in BMS
    *** partially inhibited by: xStk11ip(2-318) [substitution]
    *** unaffected by: xStk11ip(313-1099) [substitution]
    *** source: 11741830-Fig-2b
  *** xLkb1[tAb] copptby[WB] xStk11ip[tAb] is detectable
    *** cells: COS in BMS
    *** source: 11741830-Fig-2a
  *** xLkb1[tAb] copptby[WB] xTcf7l2[tAb] is undetectable
    *** cells: COS in BMS
    *** source: 11741830-Fig-2a
  *** xLkb1[tAb] locatedin(cytoplasm)[IHC] is increased itpo xStk11ip
    *** cells: HELA in BMS
    *** comment: Lkb1 colocates with Stk11ip in cytoplasm
    *** source: 11741830-Fig-3a,3d
  *** xLkb1[tAb] locatedin(nucleus)[IHC] is detectable
    *** cells: HELA in BMS
    *** source: 11741830-Fig-3a
  *** xLkb1[tAb]IP phos(S325)[phosAb] is detectable
    *** cells: SKMEL28<xLkb1> in BMS
    *** partially reqs: Braf(V600E) [RNAi]
    *** source: 19187764-Fig-4c
  *** xLkb1[tAb]IP phos(S428)[phosAb] is detectable
    *** cells: SKMEL28<xLkb1> in BMS
    *** partially reqs: Braf(V600E) [RNAi]
    *** source: 19187764-Fig-4c
  *** xLkb1[XFP] locatedin(cytoplasm)[IHC] is increased itpo xStrada
    *** cells: HELA in BMS
    *** inhibited by: xLkb1(del(303-305)/H306N) [substitution]
    *** unaffected by: xLkb1(D194A)"KD" [substitution]
    *** source: 14517248-Fig-S3
  *** xLkb1[XFP] locatedin(cytoplasm)[IHC] is increased itpo xStrada
    *** cells: HELA in BMS
    *** unaffected by: xCab39 [addition]
    *** source: 14517248-Fig-5
  *** xLkb1[XFP] locatedin(cytoplasm)[IHC] is unchanged itpo xCab39
    *** cells: HELA in BMS
    *** source: 14517248-Fig-5
  *** xLmo4(21-60)"Lim1S"[tAb] copptby[WB] Gp130[Ab] is detectable
    *** cells: HEPG2 in BMS
    *** unaffected by: xLmo4(86-125)"Lim2S" [substitution]
    *** source: 15677447-Fig-5c
  *** xLmo4(21-60)"Lim1S"[tAb] copptby[WB] Socs3[Ab] is detectable
    *** cells: HEPG2 in BMS "treated with IL6 for 60 min"
    *** unaffected by: xLmo4(86-125)"Lim2S" [substitution]
    *** source: 15677447-Fig-5c
  *** xLmo4(21-60)"Lim1S"[tAb] copptby[WB] xGp130[tAb] is detectable
    *** cells: COS1 in BMS
    *** partially inhibited by: xLmo4(86-125)"Lim2S" [substitution]
    *** inhibited by: xLmo4(79-165)"Lim2L" [substitution]
    *** source: 15677447-Fig-5b
  *** xLmo4(21-60)"Lim1S"[tAb] copptby[WB] xSocs3[tAb] is detectable
    *** cells: COS1 in BMS
    *** partially inhibited by: xLmo4(86-125)"Lim2S" [substitution]
    *** inhibited by: xLmo4(79-165)"Lim2L" [substitution]
    *** source: 15677447-Fig-5b
  *** Lmo4[Ab] copptby[WB] Gp130[Ab] is detectable
    *** cells: JURKAT<Pten~null> in BMS
    *** source: 15677447-Fig-2b
  *** Lmo4[Ab] copptby[WB] Gp130[Ab] is detectable
    *** cells: T47D in BMS
    *** source: 15677447-Fig-2b
  *** Lmo4[Ab] copptby[WB] Jak1[Ab] is detectable
    *** cells: JURKAT<Pten~null> in BMS
    *** source: 15677447-Fig-2b
  *** Lmo4[Ab] copptby[WB] Jak1[Ab] is detectable
    *** cells: T47D in BMS
    *** source: 15677447-Fig-2b
  *** Lmo4[Ab] copptby[WB] Socs3[Ab] is detectable
    *** cells: HEPG2 in BMS "treated with IL6 for 60 min"
    *** source: 15677447-Fig-3d
  *** Lmo4[Ab] copptby[WB] Stat3[Ab] is undetectable
    *** cells: JURKAT<Pten~null> in BMS
    *** source: 15677447-Fig-2b
  *** Lmo4[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: HEPG2 in BMS
    *** source: 15677447-Fig-7b
  *** Lmo4[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: T47D in BMS
    *** source: 15677447-Fig-7b
  *** xLmo4[tAb] copptby[WB] Shp2[Ab] is detectable
    *** cells: HEPG2 in BMS
    *** source: 15677447-Fig-3a
  *** xLmo4[tAb] copptby[WB] xGp130[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15677447-Fig-1a
  *** xLmo4[tAb] copptby[WB] xJak1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15677447-Fig-1b
  *** xLmo4[tAb] copptby[WB] xJak2[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15677447-Fig-1b
  *** xLmo4[tAb] copptby[WB] xSocs3[tAb] is detectable
    *** cells: HEPG2 in BMS
    *** source: 15677447-Fig-3c
  *** xLmo4[tAb] locatedin(nucleus)[IHC] is detectable
    *** cells: HEPG2 in BMS
    *** source: 15677447-Fig-7a
  *** xLrp5(1419-1615)"C3"[tAb] copptby[WB] xAxin1[tAb] is detectable
    *** cells: COS7<xAxin1><xLrp5(1419-1615)> in BMS
    *** source: 11336703-Fig-3b
  *** Lrp6[Ab] infraction(DRM)[WB] is detectable-but unchanged itao Cav1 [RNAi]
    *** cells: HELAS3 in BMS
    *** source: 20053636-Fig-1d
  *** xLrp6[Ab]IP boundby[WB] rWnt3a[Ab] is detectable
    *** cells: HEK293T<xLrp6> in BMS
    *** comment: equal amounts of rWnt3a are found in DRMs and non-DRMs
    *** source: 20053636-Fig-1b
  *** Lrp6[phosAb] phos(S1490)[phosAb] is increased itpo xGsk3?
    *** cells: HEK293 in BMS
    *** enhanced by: xGnb1 + xGng2 [addition]
    *** source: 20460648-Fig-6c
  *** xLrp6[phosAb] phos(S1490)[phosAb] is increased itpo xGsk3b
    *** cells: HEK293T<xLrp6> in BMS
    *** inhibited by: xGsk3b(mnr)"KD" [substitution]
    *** source: 16341017-Fig-1b
  *** xLrp6[phosAb] phos(S1490)[phosAb] is increased itpo xGsk3b
    *** cells: HEK293T<xLrp6> in BMS
    *** inhibited by: xGsk3b(mnr)"KD" [substitution]
    *** unaffected by: xGsk3b(R96A) [substitution]
    *** source: 16341017-Fig-1e
  *** xLrp6[phosAb] phos(S1490)[phosAb] is increased itpo xGsk3b
    *** cells: HEK293T<xLrp6><xAxin1> in BMS
    *** inhibited by: xAxin1(L396Q) [substitution]
    *** source: 18077588-Fig-5d
  *** xLrp6[phosAb] phos(S1490)[phosAb] is unchanged itpo xCsnk1a1
    *** cells: mEFs<Csnk1e~null> in BMS
    *** source: 16341017-Fig-3a
  *** xLrp6[phosAb] phos(S1490)[phosAb] is unchanged itpo xCsnk1d
    *** cells: mEFs<Csnk1e~null> in BMS
    *** source: 16341017-Fig-3a
  *** xLrp6[phosAb] phos(S1493)[phosAb] is increased itpo xCsnk1d
    *** cells: mEFs<Csnk1e~null> in BMS
    *** source: 16341017-Fig-3a
  *** xLrp6[phosAb] phos(S1493)[phosAb] is unchanged itpo xCsnk1a1
    *** cells: mEFs<Csnk1e~null> in BMS
    *** source: 16341017-Fig-3a
  *** xLrp6[tAb] copptby[WB] xCav1[tAb] is detectable
    *** cells: HEK293T<xLrp6><xCav1> in BMS
    *** source: 20053636-Fig-2e
  *** xLrp6[tAb] copptby[WB] xCsnk1g1[tAb] is detectable
    *** cells: HEK293T<xLrp6><xCsnk1g1> in BMS
    *** source: 20053636-Fig-2e
  *** xLrp6[tAb] copptby[WB] xGnb1[tAb] is detectable 
    *** cells: HEK293<xLrp6><xGnb1><xGng2> in BMS "membrane fraction"
    *** source: 20460648-Fig-6e
  *** xLrp6[tAb] oligomerization[2TagPpt] is detectable
    *** cells: HEK293T<xLrp6> in BMS
    *** inhibited by: xLrp6(mnr)"delNterm" [substitution]
    *** source: 12897152-Fig-2b
  *** xLrp6[tAb] oligomerization[2TagPpt] is detectable
    *** cells: HEK293T<xLrp6> in BMS
    *** source: 12897152-Fig-2a
  *** xLselectin[AP] secretion[AP] is increased itpo xAdam10
    *** cells: mEFs<Adam17~null><Adam10~null><xLselectin> in BMS
    *** source: 19158376-Fig-3c
  *** xLselectin[AP] secretion[AP] is increased itpo xAdam17
    *** cells: mEFs<Adam17~null><Adam10~null><xLselectin> in BMS
    *** source: 19158376-Fig-3c
  *** Lta-gene mRNA[RTPCR] is detectable
    *** cells: mSpBCs in BMS "treated with anti-Cd40 (24 hr)"
    *** unaffected by: kMekk1(1-1188)"del-kinase-domain" [addition]
    *** source: 17143273-Fig-6c
  *** Ltb-gene mRNA[RTPCR] is detectable
    *** cells: mSpBCs in BMS "treated with anti-Cd40 (24 hr)"
    *** unaffected by: kMekk1(1-1188)"del-kinase-domain" [addition]
    *** source: 17143273-Fig-6c
  *** Lyn[Ab] copptby[WB] xIL2Rb[Ab] is undetectable
    *** cells: BAFB03<xIL2Rb> in BMS
    *** source: 8483935-Fig-5c
  *** xLyn[Ab] copptby[WB] xStat3[GST] is detectable
    *** cells: SF9 in BMS
    *** source: 12244095-Fig-3
  *** Madd[Ab] prot-exp[WB] is detectable
    *** cells: CHO in BMS
    *** source: 9115275-Fig-4
  *** Madd[Ab] prot-exp[WB] is detectable
    *** cells: HELA in BMS
    *** source: 9115275-Fig-4
  *** Madd[Ab] prot-exp[WB] is detectable
    *** cells: U937 in BMS
    *** source: 9115275-Fig-4
  *** Madd[Ab] prot-exp[WB] is detectable
    *** cells: WI38 in BMS
    *** source: 9115275-Fig-4
  *** xMadd[tAb] copptby[WB] TnfR1[Ab] is detectable
    *** cells: COS in BMS
    *** unaffected by: Tnf (15 min) [stim]
    *** source: 9115275-Fig-5b
  *** Maged1-gene mRNA[RTPCR] is increased itao Ampka1 [RNAi]
    *** cells: THP1 in BMS
    *** reqs: Ampka1 [RNAi]
    *** source: 22833096-Fig-7b
  *** Malt1[Ab] snaggedby[WB] rBcl10[GST] is detectable
    *** cells: JURKAT<Pten~null> in BMS "cytoplasmic fraction"
    *** unaffected by: PMA + Ionomycin [addition]
    *** source: 14695475-Fig-1a
  *** xMalt1[tAb] copptby[WB] xBcl10[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 11262391-Fig-2b
  *** xMalt1[tAb] copptby[WB] xNik[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 11262391-Fig-2b
  *** xMalt1[tAb] copptby[WB] xRipk2[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 11262391-Fig-2b
  *** xMalt1[tAb] copptby[WB] xTbk1[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 11262391-Fig-2b
  *** xMalt1[tAb] oligomerization[2TagPpt] is increased itpo xBcl10
    *** cells: HEK293T in BMS
    *** source: 14695475-Fig-3d
  *** xMap3k12[tAb] copptby[WB] xPosh[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 12514131-Fig-3b
  *** Map4k2[Ab] copptby[WB] Mekk1[Ab] is detectable
    *** cells: RAMOS in BMS
    *** source: 11784851(D)
  *** xMap4k2[tAb]IP IVKA(MBP)[32P-ATP] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xMap4k2(K44M)"KD" [substitution]
    *** source: 9712898-Fig-2b
*** Map4k4--
  *** rMap4k4(872-1239)[GST] boundby[WB] rGbp3[His] is detectable
    *** cells: none
    *** source: 12387898-Fig-3a
  *** xMap4k4(872-1239)[tAb] copptby[WB] xGbp3[tAb] is detectable
    *** cells: HEK293T<xMap4k4(872-1239)><xGbp3> in BMS
    *** source: 12387898-Fig-3b
  *** xMap4k4[Ab]IP IVKA(MBP)[32P-ATP] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xMap4k4(D152N)"KD" [substitution]
    *** source: 9135144-Fig-3c
  *** xMap4k4[tAb] copptby[WB] Nck1[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 9135144-Fig-4a
  *** xMap4k4[tAb] snaggedby[WB] rGrb2[GST] is undetectable
    *** cells: HEK293 in BMS
    *** source: 9135144-Fig-4a
  *** xMap4k4[tAb] snaggedby[WB] rNck1[GST] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xMap4k4(P574A/P577A)"SH3-domain-mut" [substitution]
    *** inhibited by: xMap4k4(P611A/P614A)"SH3-domain-mut" [substitution]
    *** source: 9135144-Fig-4a
  *** xMap4k4[tAb]IP IVKA(MBP)[32P-ATP] is detectable
    *** cells: HEK293T<xMap4k4> in BMS
    *** inhibited by: xMap4k4(K54R) [substitution]
    *** inhibited by: xMap4k4(K54E) [substitution]
    *** source: 9890973-Fig-3a
  *** xMap4k5[Ab]IP IVKA(MBP)[32P-ATP] is increased itpo xTraf2
    *** cells: HEK293 in BMS
    *** inhibited by: xUbc13(C87A)"E2-inactive" [addition]
    *** source: 12591926-Fig-3
  *** xMap4k5[tAb] oligomerization[2TagPpt] is increased itpo (xTraf2 + xUbc13 + xUbiq)
    *** cells: HEK293 in BMS
    *** source: 12591926-Fig-4b
  *** xMap4k5[tAb]IP IVKA(MBP)[32P-ATP] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xMap4k5(T178A) [substitution]
    *** source: 9405407-Fig-2c
  *** xMap4k5[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo (xTraf2 + xUbc13 + xUbiq)
    *** cells: HEK293<xJnk?> in BMS
    *** inhibited by: xUbiq(K63R) [substitution]
    *** unaffected by: xUbiq(K48R) [substitution]
    *** source: 12591926-Fig-2b
  *** xMap4k5[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xTraf2
    *** cells: HEK293 in BMS
    *** inhibited by: xTraf2(C34A)"E3-inactive" [substitution]
    *** source: 12591926-Fig-2d
  *** xMap4k5[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xTraf2
    *** cells: HEK293<xJnk?> in BMS
    *** unaffected by: xUbc13 + xUbiq [addition]
    *** inhibited by: xUbc13(C87A) + xUbiq(K63R) [addition]
    *** comment: inhibited by cotransfection of Ubc13-AS-DNA and Ubiq(K63R)
    *** source: 12591926-Fig-2a
  *** xMap4k5[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xTraf2
    *** cells: HEK293T in BMS
    *** source: 9405407-Fig-3f
  *** xMap4k5[tAb]IP ubiq[UbAb] is increased itpo (xTraf2 + xUbc13 + xUbiq)
    *** cells: HELA in BMS
    *** inhibited by: xTraf2(C34A)"E3-inactive" [substitution]
    *** source: 12591926-Fig-5c
  *** xMap4k5[tAb]IP ubiq[UbAb] is increased itpo (xTraf2 + xUbc13 + xUbiq)
    *** cells: HELA in BMS
    *** inhibited by: xUbc13(C87A)"E2-inactive" [substitution]
    *** source: 12591926-Fig-5b
  *** xMap4k5[tAb]IP ubiq[UbAb] is increased itpo (xTraf2 + xUbc13 + xUbiq)
    *** cells: HELA in BMS
    *** inhibited by: xUbiq(K63R) [substitution]
    *** unaffected by: xUbiq(K48R) [substitution]
    *** source: 12591926-Fig-5b
  *** xMap4k5[tAb]IP ubiq[UbAb] is increased itpo (xTraf2 + xUbc13 + xUbiq)
    *** cells: HELA in BMS
    *** source: 12591926-Fig-5a
  *** xMap4k5[tAb]IP upshift[WBMS] is increased itpo (xTraf2 + xUbc13 + xUbiq)
    *** cells: HELA in BMS
    *** source: 12591926-Fig-5a
*** Mapkapk2--
  *** Mapkapk2[Ab]IP phos(T334)[phosAb] is detectable
    *** cells: RAW2647 in BMS
    *** inhibited by: PD184352 + SB203580 [addition]
    *** source: 12881422-Fig-5a
  *** Mapkapk2[Ab]IP phos(T334)[phosAb] is detectable
    *** cells: RAW2647 in BMS
    *** inhibited by: PD184352 + SB203580 [addition]
    *** source: 12881422-Fig-5b
  *** xMapkapk2[GST]IP IVKA(Crosstide)[32P-ATP] is unchanged by Ro318220
    *** cells: HEK293<xMapkapk2> in BMLS
    *** source: 9687510-Fig-9a
  *** xMapkapk2[tAb]IP IVKA(Hspb1)[32P-ATP] is increased itpo (xTak1 + xTab1)
    *** cells: HELA in BMS
    *** inhibited by: xTak1(K63W) [substitution]
    *** source: 11050078-Fig-1c
  *** Mapkapk2[tAb]IP IVKA(Hspb1)[32P-ATP] is increased itpo xMlk3
    *** cells: HEK293 in BMS
    *** inhibited by: SB203580 [addition]
    *** source: 9003778-Fig-3a
  *** xMapkapk3[GST]IP IVKA(Crosstide)[32P-ATP] is unchanged by Ro318220
    *** cells: HEK293<xMapkapk3> in BMLS
    *** source: 9687510-Fig-9a
  *** Mapre1[Ab] copptby[WB] Apc[Ab] is detectable-but unchanged itpo xPin1
    *** cells: HELA in BMS
    *** source: 11533658-Fig-6b
*** Mapt--
  *** Mapt[Ab] colocwith[IHC] Stau1[Ab] is detectable
    *** cells: SHSY5Y in BMS "differentiated with retinoic acid for 7 days"
    *** source: 15121898(D)
  *** Mapt[Ab] copptby[WB] xStau1[tAb] is detectable
    *** cells: HEK293T in BMS "infected with vaccinia vTf7-3 virus"
    *** source: 15121898(D)
  *** xMapt[Ab] phos[WBMS] is increased itpo xGsk3b
    *** cells: COS1<xMapt> in BMS
    *** unaffected by: xPpm1a [addition]
    *** source: 10644691-Fig-3a
*** Mark3--
  *** Mark3[Ab] copptby[WB] xKsr1[tAb] is detectable
    *** cells: COS in BMLS
    *** source: 11741534-Fig-3
  *** Mark3[MS] copptby[WB] xKsr1[tAb] is detectable
    *** cells: COS in BMS
    *** source: 12932319-Fig-1a
*** Mavs--
  *** Mavs[Ab] colocwith[IHC] Cycs[Ab] is detectable
    *** cells: HELA in BMS
    *** source: 16125763-Fig-S1b
  *** Mavs[Ab] copptby[WB] Traf3[Ab] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 16858409-Fig-4c
  *** Mavs[Ab] copptby[WB] Traf6[Ab] is detectable
    *** cells: HEK293<xTLR3> in BMS
    *** unaffected by: PolyIC (10 min) [stim]
    *** source: 16153868-Fig-7b
  *** Mavs[Ab] copptby[WB] Trif[Ab] is detectable
    *** cells: HEK293<xTLR3> in BMS
    *** unaffected by: PolyIC (10 min) [stim]
    *** source: 16153868-Fig-7b
  *** Mavs[Ab] copptby[WB] xTradd[tAb] is detectable
    *** cells: HEK293T in BMS
    *** enhanced by: xRig1(1-200)"2Card-domain" [addition]
    *** source: 18439848-Fig-4c
  *** xMavs[tAb] colocwith[IHC] Canx[Ab] is undetectable
    *** cells: HELA in BMS
    *** source: 16125763-Fig-S1a
  *** xMavs[tAb] copptby[WB] xAzi2[tAb] is detectable
    *** cells: HEK293<xMavs><xAzi2> in BMS
    *** source: 17142768-Fig-3a
  *** xMavs[tAb] copptby[WB] xFadd[tAb] is increased itpo xTradd
    *** cells: HEK293T in BMS
    *** source: 18439848-Fig-S8,S9
  *** xMavs[tAb] copptby[WB] xIrf1[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 16153868-Fig-7a
  *** xMavs[tAb] copptby[WB] xIrf3[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 16153868-Fig-4a
  *** xMavs[tAb] copptby[WB] xIrf3[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 16153868-Fig-7a
  *** xMavs[tAb] copptby[WB] xIrf7[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 16153868-Fig-7a
  *** xMavs[tAb] copptby[WB] xRig1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 16153868-Fig-4a
  *** xMavs[tAb] copptby[WB] xTak1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 16153868-Fig-7a
  *** xMavs[tAb] copptby[WB] xTbk1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 16153868-Fig-7a
  *** xMavs[tAb] copptby[WB] xTraf3[Ab] is detectable
    *** cells: HEK293T in BMS
    *** source: 16858409-Fig-4b
  *** xMavs[tAb] copptby[WB] xTrif[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 16153868-Fig-7a
*** Max--
  *** rMax[14C] acetyl[14C-acetyl-CoA] is unchanged by rEp300(1195-1810)
    *** cells: none
    *** source: 9288740-Fig-1a
  *** rMax[35S] boundby[WB] rPias2(269-803)[GST] is undetectable
    *** cells: none
    *** source: 9312026-Fig-2a
  *** rMax[Ab] boundby[WB] rSmad3[GST] is detectable
    *** cells: none
    *** unaffected by: rSmad3(mnr)"MH1" [substitution]
    *** inhibited by: rSmad3(mnr)"MH2" [substitution]
    *** source: 12551947-Fig-5d
  *** rMax[Ab] boundby[WB] rSmad4[GST] is detectable
    *** cells: none
    *** unaffected by: rSmad4(mnr)"MH1" [substitution]
    *** inhibited by: rSmad4(mnr)"MH2" [substitution]
    *** source: 12551947-Fig-5d
  *** Max[Ab] copptby[WB] xKat2a[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 12660246-Fig-1a
  *** Max[Ab] copptby[WB] xMyc[tAb] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: xTrrap(1899-2401) [addition]
    *** source: 12660246-Fig-5d
  *** Mcl1-gene mRNA[RTPCR] is decreased itao Pias2a [RNAi]
    *** cells: HELA in BMLS
    *** source: 15920481-Fig-1e
*** Mcp6--
  *** Mcp6-gene promo-reporter[Luc] is increased itpo xMitf
    *** cells: NIH3T3<xStat3(C661A/C663N)> in BMS
    *** partially inhibited by: xPias3 [addition]
    *** source: 15572665-Fig-4b
  *** Mcp6-gene promo-reporter[Luc] is increased itpo xMitf
    *** cells: NIH3T3<xStat3(Y705F)> in BMS
    *** inhibited by: xPias3 [addition]
    *** source: 15572665-Fig-4b
  *** Mcph1[Ab] prot-exp[WB] is detectable
    *** cells: HELA in BMS
    *** does not req: Rnf8 [RNAi]
    *** source: 18001825-Fig-S4b
*** Mda5--
  *** Mda5[Ab] copptby[WB] Azi2[Ab] is detectable
    *** cells: HELA in BMS "treated with Ifnb1 for 24 hr"
    *** source: 17142768-Fig-1b
  *** xMda5[tAb] copptby[WB] xAzi2(del(158-270))[tAb] is detectable
    *** cells: HEK293<xMda5><xAzi2(del(158-270))> in BMS
    *** source: 17142768-Fig-1d
  *** xMda5[tAb] copptby[WB] xAzi2[tAb] is detectable
    *** cells: HEK293<xMda5><xAzi2> in BMS
    *** source: 17142768-Fig-1a
  *** xMda5[tAb] copptby[WB] xMavs[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 16127453-Fig-5a
  *** xMda5[tAb] snaggedby[WB] PolyIC[agarose] is detectable
    *** cells: HEK293T in BMS
    *** source: 16116171-Fig-3f
*** Mdc1--
  *** rMdc1(1-150)"FHA"[GST] boundby[WB] Atm[Ab]IP is detectable
    *** cells: none
    *** IPfrom: HELA in BMS "treated with IR for 1 hr"
    *** inhibited by: rMdc1(1890-2089)"BRCT" [substitution]
    *** source: 20026654-Fig-S2a
  *** rMdc1(1-150)"FHA"[GST] boundby[WB] sAtm(1974-1988){phos(S1981)}[GST] is detectable
    *** cells: none
    *** inhibited by: rMdc1(1890-2089)"BRCT" [substitution]
    *** source: 20026654-Fig-S2b
  *** rMdc1(1-150)"FHA"[GST] boundby[WB] sAtm(1974-1988){phos(S1981)}[GST] is detectable
    *** cells: none
    *** inhibited by: sAtm(1974-1988) [substitution]
    *** source: 20026654-Fig-S2b
  *** rMdc1(1-150)"FHA"[GST] boundby[WB] xAtm[tAb]IP is detectable
    *** cells: none
    *** IPfrom: AT5BIVA<Atm~fmut><xAtm> in BMS "treated with IR for 1 hr"
    *** comment: inhibited by treatment of xAtm-IP with PPase
    *** inhibited by: xAtm(S1981A) [substitution]
    *** source: 20026654-Fig-4c
  *** sMdc1(709-724/pT719) boundby[SPR] rRnf8(2-160)[RU] is detectable
    *** cells: none
    *** inhibited by: rRnf8(2-160/R42A) [substitution]
    *** source: 18006705-Fig-3a
  *** sMdc1(709-724/pT719) boundby[SPR] rRnf8(2-160)[RU] is detectable
    *** cells: none
    *** inhibited by: sMdc1(709-724)"T719" [substitution]
    *** source: 18006705-Fig-3a
  *** sMdc1(743-757/pT752) boundby[SPR] rRnf8(2-160)[RU] is detectable
    *** cells: none
    *** inhibited by: rRnf8(2-160/R42A) [substitution]
    *** source: 18006705-Fig-3a
  *** sMdc1(743-757/pT752) boundby[SPR] rRnf8(2-160)[RU] is detectable
    *** cells: none
    *** inhibited by: sMdc1(743-757)"T752" [substitution]
    *** source: 18006705-Fig-3a
  *** rMdc1(1890-2089)"BRCT"[GST] boundby[WB] sH2ax(134-143){phos(S140)}[GST] is detectable
    *** cells: none
    *** inhibited by: rMdc1(1-150)"FHA" [substitution]
    *** source: 20026654-Fig-S2b
  *** rMdc1(1890-2089)"BRCT"[GST] boundby[WB] sH2ax(134-143){phos(S140)}[GST] is detectable
    *** cells: none
    *** inhibited by: sH2ax(134-143) [substitution]
    *** source: 20026654-Fig-S2b
  *** Mdc1[Ab] copptby[WB] Mre11[Ab] is detectable
    *** cells: HELA in BMS "nuclear-extracts"
    *** source: 12607003-Fig-1c
  *** Mdc1[Ab] copptby[WB] Nbs1[Ab] is detectable
    *** cells: HELA in BMS "nuclear-extracts"
    *** source: 12607003-Fig-1c
  *** Mdc1[Ab] copptby[WB] Rad50[Ab] is detectable
    *** cells: HELA in BMS "nuclear-extracts"
    *** source: 12607003-Fig-1c
  *** Mdc1[Ab] copptby[WB] Rnf8[Ab] is detectable
    *** cells: HEK293T in BMS
    *** source: 18001824-Fig-2a
  *** Mdc1[Ab] snaggedby[WB] sH2ax(123-143){phos(S140)}[GST] is detectable
    *** cells: HELA in BMS "nuclear-extracts"
    *** inhibited by: sH2ax(123-143) [substitution]
    *** source: 16377563-Fig-1b
  *** xMdc1[tAb] copptby[WB] xNbs1[STag] is detectable
    *** cells: HEK293T<xMdc1><xNbs1> in BMS
    *** inhibited by: xNbs1(del(24-108))"D1" [substitution]
    *** inhibited by: xNbs1(del(109-196))"D2" [substitution]
    *** partially inhibited by: xNbs1(del(361-460))"D3" [substitution]
    *** inhibited by: xNbs1(del(261-460))"D4" [substitution]
    *** inhibited by: xNbs1(del(219-460))"D5" [substitution]
    *** source: 18678890-Fig-5b
  *** xMdc1[tAb] copptby[WB] xNbs1[STag] is detectable
    *** cells: HELA<xMdc1><xNbs1> in BMS
    *** unaffected by: xMdc1(del(33-154))"D1" [substitution]
    *** unaffected by: xMdc1(del(125-170))"D2" [substitution]
    *** inhibited by: xMdc1(del(200-420))"D3" [substitution]
    *** unaffected by: xMdc1(del(421-624))"D4" [substitution]
    *** unaffected by: xMdc1(del(625-1129))"D5" [substitution]
    *** unaffected by: xMdc1(del(1130-1661))"D6" [substitution]
    *** unaffected by: xMdc1(del(1662-1892))"D7" [substitution]
    *** inhibited by: xMdc1(del(1893-2092))"D8" [substitution]
    *** source: 18678890-Fig-2e
  *** xMdc1[tAb] copptby[WB] xRnf8[SBP] is detectable
    *** cells: HEK293T<xMdc1><xRnf8> in BMS
    *** inhibited by: xRnf8(mnr)"delFHA" [substitution]
    *** source: 18001825-Fig-3e
  *** xMdc1[tAb] snaggedby[WB] rRnf8[GST] is detectable
    *** cells: HEK293T<xMdc1> in BMS
    *** inhibited by: xMdc1(del(698-768)) [substitution]
    *** source: 18001825-Fig-3c
  *** xMdc1[tAb] snaggedby[WB] sH2ax(123-143){phos(S140)}[GST] is detectable
    *** cells: HEK293T<xMdc1> in BMS "nuclear-extracts"
    *** inhibited by: sH2ax(123-143) [substitution]
    *** source: 16377563-Fig-1d
  *** xMdc1[tAb] snaggedby[WB] sH2ax(123-143){phos(S140)}[GST] is detectable
    *** cells: HEK293T<xMdc1> in BMS "nuclear-extracts"
    *** inhibited by: xMdc1(mnr)"delBRCT" [substitution]
    *** source: 16377563-Fig-1d
*** Mdm2--
  *** Mdm2-gene mRNA[RTPCR] is decreased itao Setd7 [RNAi]
    *** cells: U2OS in BMS
    *** source: 15525938-Fig-S3
  *** Mdm2-gene mRNA[RTPCR] is increased itpo xSetd7
    *** cells: U2OS in BMS
    *** source: 15525938-Fig-S3
  *** Mdm2-gene promo-reporter[Luc] is increased itpo xHipk2
    *** cells: H1299<Tp53~null><xTp53> in BMS
    *** inhibited by: xHipk2(1-864) [substitution]
    *** source: 11780126-Fig-3b
  *** Mdm2-gene promo-reporter[Luc] is increased itpo xHipk2
    *** cells: H1299<Tp53~null><xTp53> in BMS
    *** source: 11780126-Fig-3a
  *** xMdm2(1-440)[Ab] prot-exp[WB] is increased itpo xP14Arf
    *** cells: U2OS<xMdm2(1-440)> in BMS
    *** source: 9724636-Fig-6b
  *** xMdm2(6-339)[Ab] prot-exp[WB] is increased itpo xP14Arf
    *** cells: U2OS<xMdm2(6-339)> in BMS
    *** source: 9724636-Fig-6b
  *** xMdm2(C464A)[Ab] boundto(Cdkn1a-gene)[ChIP] is increased itpo xTp53
    *** cells: H1299<Tp53~null><xMdm2(C464A)><xMdm4> in BMS
    *** inhibited by: xCbp + xTip60 [addition]
    *** source: 18485870-Fig-4c
  *** xMdm2(C464A)[Ab] boundto(Cdkn1a-gene)[ChIP] is increased itpo xTp53
    *** cells: H1299<Tp53~null><xMdm2(C464A)><xMdm4> in BMS
    *** unaffected by: xTp53(K120R/K164R/K370R/K372R/K373R/K381R/K382R/K386R)"8KR" [substitution]
    *** source: 18485870-Fig-4c
  *** xMdm2(C464A)[Ab] boundto(Cdkn1a-gene)[ChIP] is increased itpo xTp53(K120R/K164R/K370R/K372R/K373R/K381R/K382R/K386R)"8KR"
    *** cells: H1299<Tp53~null><xMdm2(C464A)><xMdm4> in BMS
    *** unaffected by: xCbp + xTip60 [addition]
    *** source: 18485870-Fig-4c
  *** xMdm2(C464A)[Ab] boundto(Mdm2-gene)[ChIP] is unchanged itpo xTp53
    *** cells: H1299<Tp53~null><xMdm2(C464A)><xMdm4> in BMS
    *** unaffected by: xCbp + xTip60 [addition]
    *** source: 18485870-Fig-4c
  *** xMdm2(C464A)[Ab] boundto(Mdm2-gene)[ChIP] is unchanged itpo xTp53
    *** cells: H1299<Tp53~null><xMdm2(C464A)><xMdm4> in BMS
    *** unaffected by: xTp53(K120R/K164R/K370R/K372R/K373R/K381R/K382R/K386R)"8KR" [substitution]
    *** source: 18485870-Fig-4c
  *** xMdm2(C464A)[Ab] boundto(Mdm2-gene)[ChIP] is unchanged itpo xTp53(K120R/K164R/K370R/K372R/K373R/K381R/K382R/K386R)"8KR"
    *** cells: H1299<Tp53~null><xMdm2(C464A)><xMdm4> in BMS
    *** unaffected by: xCbp + xTip60 [addition]
    *** source: 18485870-Fig-4c
  *** xMdm2(C464A)[Ab] boundto(Pirh2-gene)[ChIP] is unchanged itpo xTp53
    *** cells: H1299<Tp53~null><xMdm2(C464A)><xMdm4> in BMS
    *** unaffected by: xCbp + xTip60 [addition]
    *** source: 18485870-Fig-S10
  *** xMdm2(C464A)[Ab] boundto(Pirh2-gene)[ChIP] is unchanged itpo xTp53
    *** cells: H1299<Tp53~null><xMdm2(C464A)><xMdm4> in BMS
    *** unaffected by: xTp53(K120R/K164R/K370R/K372R/K373R/K381R/K382R/K386R)"8KR" [substitution]
    *** source: 18485870-Fig-S10
  *** xMdm2(C464A)[Ab] boundto(Pirh2-gene)[ChIP] is unchanged itpo xTp53(K120R/K164R/K370R/K372R/K373R/K381R/K382R/K386R)"8KR"
    *** cells: H1299<Tp53~null><xMdm2(C464A)><xMdm4> in BMS
    *** unaffected by: xCbp + xTip60 [addition]
    *** source: 18485870-Fig-S10
  *** xMdm2(C464A)[Ab] boundto(Tp53i3-gene)[ChIP] is increased itpo xTp53
    *** cells: H1299<Tp53~null><xMdm2(C464A)><xMdm4> in BMS
    *** inhibited by: xCbp + xTip60 [addition]
    *** source: 18485870-Fig-4c
  *** xMdm2(C464A)[Ab] boundto(Tp53i3-gene)[ChIP] is increased itpo xTp53
    *** cells: H1299<Tp53~null><xMdm2(C464A)><xMdm4> in BMS
    *** unaffected by: xTp53(K120R/K164R/K370R/K372R/K373R/K381R/K382R/K386R)"8KR" [substitution]
    *** source: 18485870-Fig-4c
  *** xMdm2(C464A)[Ab] boundto(Tp53i3-gene)[ChIP] is increased itpo xTp53(K120R/K164R/K370R/K372R/K373R/K381R/K382R/K386R)"8KR"
    *** cells: H1299<Tp53~null><xMdm2(C464A)><xMdm4> in BMS
    *** unaffected by: xCbp + xTip60 [addition]
    *** source: 18485870-Fig-4c
  *** xMdm2(mnr)"del-NES"[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: mEFs<Tp53~null><Mdm2~null><xMdm4><xMdm2(mnr)"del-NES"> in BMS
    *** source: 12963717-Fig-4d
  *** xMdm2(mnr)"del-NLS"[Ab] locatedin(cytoplasm)[IHC] is detectable
    *** cells: mEFs<Tp53~null><Mdm2~null><xMdm4><xMdm2(mnr)"del-NLS"> in BMS
    *** source: 12963717-Fig-4d
  *** xMdm2(S166A)[Ab] locatedin(cytoplasm)[IHC] is detectable
    *** cells: HEK293<xMdm2> in BMS
    *** source: 11504915-Fig-3d
  *** xMdm2(S166A/S186A)[Ab] locatedin(cytoplasm)[IHC] is detectable
    *** cells: HEK293<xMdm2> in BMS
    *** unaffected by: xAkt1(mnr)"CA" [addition]
    *** unaffected by: Igf1 [addition]
    *** source: 11504915-Fig-3d
  *** xMdm2(S186A)[Ab] locatedin(cytoplasm)[IHC] is detectable
    *** cells: HEK293<xMdm2> in BMS
    *** source: 11504915-Fig-3d
  *** rMdm2[32P] phos[32P-ATP] is unchanged by (xCyclinB?[Ab]IP + xCdk1[Ab]IP)
    *** cells: none
    *** IPfrom: SF9 in BMS
    *** comment: CyclinA2 and Cdk2 were cotransfected and IPed as a complex
    *** source: 11359766-Fig-2c
  *** rMdm2[32P] phos[32P-ATP] is unchanged by (xCyclinB?[Ab]IP + xCdk1[Ab]IP)
    *** cells: none
    *** IPfrom: SF9 in BMS
    *** comment: CyclinA2 and Cdk2 were cotransfected and IPed as a complex
    *** source: 11359766-Fig-2d
  *** rMdm2[32P] phos[32P-ATP] is unchanged by (xCyclinD?[Ab]IP + xCdk4[Ab]IP)
    *** cells: none
    *** IPfrom: SF9 in BMS
    *** comment: CyclinA2 and Cdk4 were cotransfected and IPed as a complex
    *** source: 11359766-Fig-2b
  *** rMdm2[32P] phos[32P-ATP] is unchanged by (xCyclinE?[Ab]IP + xCdk2[Ab]IP)
    *** cells: none
    *** IPfrom: SF9 in BMS
    *** comment: CyclinA2 and Cdk2 were cotransfected and IPed as a complex
    *** source: 11359766-Fig-2a
  *** xMdm2[Ab] boundto(Cdkn1a-gene)[ChIP] is increased itpo xTp53
    *** cells: H1299<Tp53~null><xMdm2> in BMS
    *** inhibited by: xCbp + xTip60 [addition]
    *** source: 18485870-Fig-4a
  *** xMdm2[Ab] boundto(Cdkn1a-gene)[ChIP] is increased itpo xTp53
    *** cells: H1299<Tp53~null><xMdm2> in BMS
    *** unaffected by: xTp53(K120R/K164R/K370R/K372R/K373R/K381R/K382R/K386R)"8KR" [substitution]
    *** source: 18485870-Fig-4a
  *** xMdm2[Ab] boundto(Cdkn1a-gene)[ChIP] is increased itpo xTp53(K120R/K164R/K370R/K372R/K373R/K381R/K382R/K386R)"8KR"
    *** cells: H1299<Tp53~null><xMdm2> in BMS
    *** unaffected by: xCbp + xTip60 [addition]
    *** source: 18485870-Fig-4a
  *** xMdm2[Ab] copptby[WB] Ep300[Ab] is detectable
    *** cells: mEFs<Tp53~null><Mdm2~null><xMdm2> in BMS
    *** enhanced by: xMdm2(S166D) [substitution]
    *** enhanced by: xMdm2(S186D) [substitution]
    *** enhanced by: xMdm2(S166D/S186D) [substitution]
    *** source: 11715018-Fig-7b
  *** xMdm2[Ab] copptby[WB] xCdkn2a[tAb] is undetectable
    *** cells: HELA<xMdm2><xCdkn2a> in BMS
    *** source: 9529249-Fig-1c
  *** Mdm2[Ab] locatedin(cytoplasm)[IHC] is detectable
    *** cells: MCF7 in BMLS
    *** source: 11504915-Fig-3a
  *** Mdm2[Ab] locatedin(cytoplasm)[IHC] is detectable
    *** cells: NIH3T3<xAkt1(mnr)"DN"> in BMS
    *** source: 11715018-Fig-4
  *** xMdm2[Ab] locatedin(cytoplasm)[IHC] is increased itpo xAkt1(mnr)"KD"
    *** cells: HEK293<xMdm2> in BMS
    *** unaffected by: Igf1 [addition]
    *** source: 11504915-Fig-3a
  *** xMdm2[Ab] locatedin(cytoplasm)[IHC] is increased itpo xAkt1(mnr)"KD"
    *** cells: hKerats<xMdm2> in BMLS
    *** source: 11504915-Fig-3c
  *** xMdm2[Ab] locatedin(cytoplasm)[IHC] is increased itpo xPi3k(mnr)"DN"
    *** cells: HEK293<xMdm2> in BMS
    *** source: 11504915-Fig-3a
  *** xMdm2[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: HEK293<xMdm2> in BMS
    *** source: 11504915-Fig-3b
  *** xMdm2[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: HEK293<xMdm2> in BMS
    *** source: 11504915-Fig-3d
  *** xMdm2[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: hKerats<xMdm2> in BMLS
    *** source: 11504915-Fig-3c
  *** Mdm2[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: NIH3T3<xErbb2> in BMS
    *** source: 11715018-Fig-4
  *** Mdm2[Ab] locatedin(nucleus)[IHC] is increased itpo xAkt1(mnr)"CA"
    *** cells: MCF7 in BMLS
    *** source: 11504915-Fig-3a
  *** xMdm2[Ab] locatedin(nucleus)[IHC] is unchanged itpo xCrm1
    *** cells: U2OS<xTp53><xMdm2> in BMS
    *** source: 11713287-Fig-7
  *** Mdm2[Ab] locatedin(perinuclear-region)[IHC] is detectable
    *** cells: hKerats in BMLS
    *** source: 11504915-Fig-3c
  *** Mdm2[Ab] prot-exp[WB] is decreased itao Tp53 [RNAi]
    *** cells: MCF7 in BMS
    *** source: 12963717-Fig-3a
  *** xMdm2[Ab] prot-exp[WB] is decreased itpo xP14Arf
    *** cells: HELA<xMdm2><xTp53> in BMS
    *** unaffected by: xCdkn2a [addition]
    *** source: 9529249-Fig-3c
  *** Mdm2[Ab] prot-exp[WB] is increased itao Cop1 [RNAi]
    *** cells: U2OS in BMS
    *** source: 15103385-Fig-3a
  *** Mdm2[Ab] prot-exp[WB] is increased itao Huwe1 [RNAi]
    *** cells: A549 in BMS
    *** source: 15989956-Fig-S7
  *** Mdm2[Ab] prot-exp[WB] is increased itao Huwe1 [RNAi]
    *** cells: HCT116 in BMS
    *** reqs: Tp53 [KO]
    *** source: 15989956-Fig-5e
  *** Mdm2[Ab] prot-exp[WB] is increased itao Huwe1 [RNAi]
    *** cells: MCF7 in BMS
    *** source: 15989956-Fig-S7
  *** Mdm2[Ab] prot-exp[WB] is increased itao Huwe1 [RNAi]
    *** cells: U2OS in BMS
    *** source: 15989956-Fig-8a
  *** Mdm2[Ab] prot-exp[WB] is increased itpo xErbb2
    *** cells: NIH3T3 in BMS
    *** source: 11715018-Fig-2d
  *** xMdm2[Ab] prot-exp[WB] is increased itpo xMdm4
    *** cells: H1299<Tp53~null><xMdm2> in BMS
    *** source: 11606419-Fig-1d
  *** Mdm2[Ab] prot-exp[WB] is increased itpo xP14Arf
    *** cells: U2OS in BMS
    *** source: 9724636-Fig-4
  *** Mdm2[Ab] prot-exp[WB] is increased itpo xP14Arf
    *** cells: U2OS in BMS
    *** source: 15989956-Fig-S13
  *** xMdm2[Ab] prot-exp[WB] is increased itpo xP14Arf
    *** cells: U2OS<xMdm2> in BMS
    *** source: 9724636-Fig-6b
  *** Mdm2[Ab] prot-exp[WB] is unchanged itao Cop1 [RNAi]
    *** cells: U2OS in BMS
    *** source: 15989956-Fig-8a
  *** Mdm2[Ab] prot-exp[WB] is unchanged itao Mdm4 [RNAi]
    *** cells: MCF7 in BMS
    *** source: 12963717-Fig-2b
  *** Mdm2[Ab] prot-exp[WB] is unchanged itao Mdm4 [RNAi]
    *** cells: MCF7 in BMS
    *** source: 12963717-Fig-3a
  *** Mdm2[Ab] prot-exp[WB] is unchanged itao Mdm4 [RNAi]
    *** cells: U2OS in BMS
    *** source: 16163388-Fig-4a
  *** Mdm2[Ab] prot-exp[WB] is unchanged itao Pirh2 [RNAi]
    *** cells: U2OS in BMS
    *** source: 15989956-Fig-8a
  *** xMdm2[Ab] prot-exp[WB] is unchanged itpo xCdkn2a
    *** cells: HELA<xMdm2><xTp53> in BMS
    *** source: 9529249-Fig-4c
  *** Mdm2[Ab] prot-exp[WB] is unchanged itpo xCdkn2a
    *** cells: U2OS in BMS
    *** source: 9724636-Fig-4
  *** Mdm2[Ab] prot-exp[WB] is unchanged itpo xPin1
    *** cells: U2OS in BMS
    *** source: 12397361-Fig-3a
  *** xMdm2[Ab] prot-stability[35S-pulse-chase] is decreased itpo xP14Arf
    *** cells: HELA<xMdm2> in BMS
    *** partially reversed by: xTp53 [addition]
    *** source: 9529249-Fig-4b
  *** xMdm2[Ab] prot-stability[35S-pulse-chase] is increased itpo xTp53
    *** cells: HELA<xMdm2> in BMS
    *** inhibited by: xP14Arf [addition]
    *** source: 9529249-Fig-4b
  *** xMdm2[Ab] prot-stability[CHX-WB] is detectable
    *** cells: U2OS<xMdm2> in BMS
    *** enhanced by: xMdm2(S395A) [substitution]
    *** unaffected by: xMdm2(S395D) [substitution]
    *** source: 15029243-Fig-4b
  *** Mdm2[Ab]IP phos(S407)[phosAb] is detectable
    *** cells: COS1 in BMS
    *** source: 14654783-Fig-1b
*** Mdm4--
  *** xMdm4[Ab] boundto(Cdkn1a-gene)[ChIP] is increased itpo xTp53
    *** cells: H1299<Tp53~null><xMdm2(C464A)><xMdm4> in BMS
    *** inhibited by: xCbp + xTip60 [addition]
    *** source: 18485870-Fig-4c
  *** xMdm4[Ab] boundto(Cdkn1a-gene)[ChIP] is increased itpo xTp53
    *** cells: H1299<Tp53~null><xMdm2(C464A)><xMdm4> in BMS
    *** unaffected by: xTp53(K120R/K164R/K370R/K372R/K373R/K381R/K382R/K386R)"8KR" [substitution]
    *** source: 18485870-Fig-4c
  *** xMdm4[Ab] boundto(Cdkn1a-gene)[ChIP] is increased itpo xTp53(K120R/K164R/K370R/K372R/K373R/K381R/K382R/K386R)"8KR"
    *** cells: H1299<Tp53~null><xMdm2(C464A)><xMdm4> in BMS
    *** unaffected by: xCbp + xTip60 [addition]
    *** source: 18485870-Fig-4c
  *** xMdm4[Ab] boundto(Mdm2-gene)[ChIP] is unchanged itpo xTp53
    *** cells: H1299<Tp53~null><xMdm2(C464A)><xMdm4> in BMS
    *** unaffected by: xCbp + xTip60 [addition]
    *** source: 18485870-Fig-4c
  *** xMdm4[Ab] boundto(Mdm2-gene)[ChIP] is unchanged itpo xTp53
    *** cells: H1299<Tp53~null><xMdm2(C464A)><xMdm4> in BMS
    *** unaffected by: xTp53(K120R/K164R/K370R/K372R/K373R/K381R/K382R/K386R)"8KR" [substitution]
    *** source: 18485870-Fig-4c
  *** xMdm4[Ab] boundto(Mdm2-gene)[ChIP] is unchanged itpo xTp53(K120R/K164R/K370R/K372R/K373R/K381R/K382R/K386R)"8KR"
    *** cells: H1299<Tp53~null><xMdm2(C464A)><xMdm4> in BMS
    *** unaffected by: xCbp + xTip60 [addition]
    *** source: 18485870-Fig-4c
  *** xMdm4[Ab] boundto(Pirh2-gene)[ChIP] is unchanged itpo xTp53
    *** cells: H1299<Tp53~null><xMdm2(C464A)><xMdm4> in BMS
    *** unaffected by: xCbp + xTip60 [addition]
    *** source: 18485870-Fig-S10
  *** xMdm4[Ab] boundto(Pirh2-gene)[ChIP] is unchanged itpo xTp53
    *** cells: H1299<Tp53~null><xMdm2(C464A)><xMdm4> in BMS
    *** unaffected by: xTp53(K120R/K164R/K370R/K372R/K373R/K381R/K382R/K386R)"8KR" [substitution]
    *** source: 18485870-Fig-S10
  *** xMdm4[Ab] boundto(Pirh2-gene)[ChIP] is unchanged itpo xTp53(K120R/K164R/K370R/K372R/K373R/K381R/K382R/K386R)"8KR"
    *** cells: H1299<Tp53~null><xMdm2(C464A)><xMdm4> in BMS
    *** unaffected by: xCbp + xTip60 [addition]
    *** source: 18485870-Fig-S10
  *** xMdm4[Ab] boundto(Tp53i3-gene)[ChIP] is increased itpo xTp53
    *** cells: H1299<Tp53~null><xMdm2(C464A)><xMdm4> in BMS
    *** inhibited by: xCbp + xTip60 [addition]
    *** source: 18485870-Fig-4c
  *** xMdm4[Ab] boundto(Tp53i3-gene)[ChIP] is increased itpo xTp53
    *** cells: H1299<Tp53~null><xMdm2(C464A)><xMdm4> in BMS
    *** unaffected by: xTp53(K120R/K164R/K370R/K372R/K373R/K381R/K382R/K386R)"8KR" [substitution]
    *** source: 18485870-Fig-4c
  *** xMdm4[Ab] boundto(Tp53i3-gene)[ChIP] is increased itpo xTp53(K120R/K164R/K370R/K372R/K373R/K381R/K382R/K386R)"8KR"
    *** cells: H1299<Tp53~null><xMdm2(C464A)><xMdm4> in BMS
    *** unaffected by: xCbp + xTip60 [addition]
    *** source: 18485870-Fig-4c
  *** Mdm4[Ab] prot-exp[WB] is unchanged itao Tp53 [RNAi]
    *** cells: MCF7 in BMS
    *** source: 12963717-Fig-3a
  *** Mdm4[Ab] prot-exp[WB] is unchanged itpo xTp53
    *** cells: H1299<Tp53~null> in BMS
    *** unaffected by: xTp53(K120R/K164R/K370R/K372R/K373R/K381R/K382R/K386R)"8KR" [substitution]
    *** source: 18485870-Fig-7a
  *** rMdm4[phosAb] phos(S342)[phosAb] is unchanged by rCsnk1a1
    *** cells: none
    *** source: 16163388-Fig-8a
  *** rMdm4[phosAb] phos(S367)[phosAb] is unchanged by rCsnk1a1
    *** cells: none
    *** source: 16163388-Fig-8a
  *** xMdm4[XFP] locatedin(cytoplasm)[IHC] is detectable
    *** cells: mEFs<Tp53~null><Mdm2~null><xMdm4> in BMS
    *** source: 12963717-Fig-4d
  *** Med1[Ab] copptby[WB] Cdk8[Ab] is unchanged itao Med23 [KO]
    *** cells: mESCs in BMS
    *** source: 11934987-Fig-1
  *** Med1[Ab] snaggedby[WB] rElk1(TAD){phos}[Gal4-DBD-G5TATA] is detectable
    *** cells: mESCs in BMS "nuclear extracts"
    *** reqs: Med23 [KO]
    *** inhibited by: rElk1(TAD) [substitution]
    *** comment: rElk1(TAD) was phosed by Erk2{act}
    *** source: 11934987-Fig-3d
  *** Med6[Ab] copptby[WB] Cdk8[Ab] is increased itao Med23 [KO]
    *** cells: mESCs in BMS
    *** source: 11934987-Fig-1
  *** Med6[Ab] snaggedby[WB] rElk1(TAD){phos}[Gal4-DBD-G5TATA] is detectable
    *** cells: mESCs in BMS "nuclear extracts"
    *** reqs: Med23 [KO]
    *** inhibited by: rElk1(TAD) [substitution]
    *** comment: rElk1(TAD) was phosed by Erk2{act}
    *** source: 11934987-Fig-3d
*** Med14--
  *** Med14[Ab] copptby[WB] Cdk8[Ab] is unchanged itao Med23 [KO]
    *** cells: mESCs in BMS
    *** source: 11934987-Fig-1
  *** Med14[Ab] snaggedby[WB] rMyc[GST] is undetectable
    *** cells: HELA in BMS "nuclear-extracts"
    *** source: 12660246-Fig-2a
  *** Med16[Ab] copptby[WB] Cdk8[Ab] is decreased itao Med23 [KO]
    *** cells: mESCs in BMS
    *** source: 11934987-Fig-1
  *** Med23[Ab] snaggedby[WB] rElk1(307-428){phos}[Gal4-DBD-G5TATA] is detectable
    *** cells: mESCs in BMS "nuclear extracts"
    *** inhibited by: rElk1(307-428) [substitution]
    *** source: 14506297-Fig-3
  *** Med23[Ab] snaggedby[WB] rElk1(TAD){phos}[GST] is detectable
    *** cells: HELA in BMS "nuclear extracts"
    *** inhibited by: rElk1(TAD) [substitution]
    *** comment: rElk1(TAD) was phosed by Erk2{act}
    *** source: 11934987-Fig-3c
*** Mef2c--
  *** xMef2c(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMkk6(S207E/T211E)"CA"
    *** cells: RAW2647 in BMS
    *** inhibited by: xMef2c(TAD/S387A) [substitution]
    *** inhibited by: xMef2c(TAD/T293A/T300A) [substitution]
    *** unaffected by: xMef2c(TAD/S387A) [substitution]
    *** source: 9069290-Fig-3e
  *** xMef2c(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMkk6(S207E/T211E)"CA"
    *** cells: THP1 in BMS
    *** source: 9069290-Fig-2c
  *** rMef2c[32P] phos[32P-ATP] is unchanged by rJnk1
    *** cells: none
    *** source: 9069290-Fig-1d
  *** xMek?(mnr)"SDSE"[tAb] copptby[WB] xErk?[tAb] is detectable
    *** cells: C2C12<xErk?><xMek?(mnr)"SDSE"> in BMS
    *** enhanced by: xIL17Rd [addition]
    *** enhanced by: xIL17Rd(Y330F) [addition]
    *** unaffected by: xIL17Rd(1-356) [addition]
    *** source: 15239952-Fig-5a
  *** xMek?(mnr)"SDSE"[tAb] copptby[WB] xIL17Rd[tAb] is detectable
    *** cells: C2C12<xMek?(mnr)"SDSE"><xIL17Rd> in BMS
    *** source: 15239952-Fig-2a
  *** xMek?(mnr)"SDSE"[tAb] copptby[WB] xIL17Rd[tAb] is detectable
    *** cells: C2C12<xMek?(mnr)"SDSE"><xIL17Rd> in BMS
    *** unaffected by: xIL17Rd(1-565) [substitution]
    *** unaffected by: xIL17Rd(1-443) [substitution]
    *** unaffected by: xIL17Rd(1-395) [substitution]
    *** inhibited by: xIL17Rd(1-356) [substitution]
    *** unaffected by: xIL17Rd(Y330F) [addition]
    *** source: 15239952-Fig-2e
  *** xMek?[phosAb] phos(SMANS)[phosAb] is increased itpo xHras(G12V)
    *** cells: C2C12<xMek?><xIL17Rd> in BMS
    *** bkg inhibited by: xMek?(mnr)"SASA" [substitution]
    *** source: 15239952-Fig-2a
  *** xMek?[phosAb] phos(SMANS)[phosAb] is increased itpo xHras(G12V)
    *** cells: C2C12<xMek?><xIL17Rd> in BMS
    *** unaffected by: xMek?(mnr)"delN" [substitution]
    *** source: 15239952-Fig-5b
  *** xMek?[tAb] copptby[WB] xErk?[tAb] is detectable
    *** cells: C2C12<xErk?><xMek?> in BMS
    *** inhibited by: xMek?(mnr)"delN" [substitution]
    *** source: 15239952-Fig-5b
  *** xMek?[tAb] copptby[WB] xErk?[tAb] is detectable
    *** cells: C2C12<xErk?><xMek?> in BMS
    *** partially inhibited by: xMek?(mnr)"SDSE" [substitution]
    *** source: 15239952-Fig-5a
  *** xMek?[tAb] copptby[WB] xIL17Rd[tAb] is increased itpo xHras(G12V)
    *** cells: C2C12<xIL17Rd><xMek?> in BMS
    *** unaffected by: xMek?(mnr)"delN" [substitution]
    *** source: 15239952-Fig-5b
  *** xMek?[tAb] copptby[WB] xIL17Rd[tAb] is increased itpo xHras(G12V)
    *** cells: C2C12<xMek?><xIL17Rd> in BMS
    *** inhibited by: xMek?(mnr)"SASA" [substitution]
    *** source: 15239952-Fig-2a
  *** xMek?[XFP] locatedin(cytoplasm)[IHC] is detectable
    *** cells: HELA<xMek?> in BMS
    *** source: 15239952-Fig-5b
  *** rMek1 IVKA(Erk?,MBP)[32P-ATP] is unchanged by rLamtor3
    *** cells: none
    *** source: 9733512-Fig-2b
  *** rMek1 IVKA(Erk2)[32P-ATP] is detectable-but unchanged by PS1145
    *** cells: none
    *** source: 15199157-Fig-3d
*** Mek1--
  *** rMek1(265-301)[32P] phos[32P-ATP] is unchanged by rMek1(mnr)"CA"
    *** cells: none
    *** source: 9677429-Fig-4
  *** rMek1(265-301)[32P] phos[32P-ATP] is unchanged by rMek2(mnr)"CA"
    *** cells: none
    *** source: 9677429-Fig-4
  *** rMek1(S218D/S222D) IVKA(Erk?,MBP)[32P-ATP] is increased by rLamtor3
    *** cells: none
    *** source: 9733512-Fig-2c
  *** xMek1(S218D/S222D)"CA"[tAb]IP phos(S298)[phosAb] is decreased itpo xErk1
    *** cells: COS1 in BMLS
    *** source: 14993270-Fig-3b
  *** rMek1[32P] phos[32P-ATP] is unchanged by rLamtor3
    *** cells: none
    *** source: 9733512-Fig-2a
  *** rMek1[32P] phos[32P-ATP] is unchanged by rMekk4(CatDom)
    *** cells: none
    *** source: 9305639-Fig-9a
  *** rMek1[Ab] boundby[WB] xErk2[Ab]IP is detectable
    *** cells: none
    *** IPfrom: CHO<xErk2> in BMLS
    *** comment: decreased when CHO<xErk2> were treated with PMA (15 min)
    *** unaffected by: xErk2(S246A/P247A/S248A) [substitution]
    *** source: 18760948-Fig-1e
  *** Mek1[Ab] copptby[WB] xBrap[tAb] is increased itpo xKsr1
    *** cells: HEK293<xBrap> in BMS
    *** source: 18332145-Fig-4d
  *** Mek1[Ab] copptby[WB] xKsr1[tAb] is detectable
    *** cells: BALB3T3<xKsr1> in BMLS
    *** unaffected by: Pdgf (5,15,60 min) [stim]
    *** source: 9858547-Fig-4b
  *** Mek1[Ab] copptby[WB] xKsr1[tAb] is detectable
    *** cells: COS7 in BMLS
    *** unaffected by: Egf (3 min) [stim]
    *** unaffected by: xKsr1(D731A/D748A) [substitution]
    *** source: 15084597-Table-1,3
  *** Mek1[Ab] copptby[WB] xRaf1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: xRaf1(T491A/S494A) [substitution]
    *** unaffected by: xRaf1(T491E/S494D) [substitution]
    *** unaffected by: xRaf1(T491E/S494D/S338D/S341D) [substitution]
    *** source: 11447113-Fig-4
  *** Mek1[Ab] infraction(cytoplasmic)[WB] is detectable
    *** cells: NIH3T3 in BMS "stimulated with serum"
    *** source: 15713638-Fig-6b
  *** Mek1[Ab] infraction(cytoplasmic)[WB] is detectable
    *** cells: HELA<xDusp6> in BMS
    *** source: 15269220-Fig-1d
  *** Mek1[Ab] infraction(cytoplasmic)[WB] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 15269220-Fig-1c
  *** Mek1[Ab] infraction(cytoplasmic)[WB] is detectable
    *** cells: NIH3T3<xDusp6> in BMS
    *** source: 15269220-Fig-1c
  *** Mek1[MS] copptby[WB] xKsr1[tAb] is detectable
    *** cells: COS in BMS
    *** source: 12932319-Fig-1a
  *** rMek1[tAb] boundby[WB] rIqGap1[GST] is detectable
    *** cells: none
    *** enhanced by: rErk1 [addition]
    *** source: 16135787-Fig-9a
  *** rMek1[tAb] boundby[WB] rIqGap1[GST] is detectable
    *** cells: none
    *** source: 16135787-Fig-1a
  *** rMek1[tAb] boundby[WB] rIqGap1[GST] is detectable
    *** cells: none
    *** unaffected by: rErk2 [addition]
    *** source: 16135787-Fig-9b
  *** xMek1[tAb] copptby[WB] xErk2[tAb] is increased itpo xRac1(Q61L)"CA"
    *** cells: COS1<xMek1><xErk2> in BMLS
    *** inhibited by: xMek1(S298A) [substitution]
    *** unaffected by: xMek1(T292A) [substitution]
    *** source: 14993270-Fig-1
  *** xMek1[tAb] copptby[WB] xGadd45b[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 14743220-Fig-1a
  *** xMek1[tAb] copptby[WB] xGit1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 14701758-Fig-2a
  *** xMek1[tAb] copptby[WB] xKsr1[tAb] is detectable
    *** cells: mEFs<Ksr1~null><xKsr1><xMek1> in BMS
    *** inhibited by: xMek1(del(270-307))"dPRS" [substitution]
    *** source: 19541618-Fig-1b
  *** xMek1[tAb] copptby[WB] xKsr1[tAb] is detectable
    *** cells: mEFs<Ksr1~null><xKsr1><xMek1> in BMS
    *** inhibited by: xMek1(del(270-307))"dPRS" [substitution]
    *** unaffected by: xMek1(L274S) [substitution]
    *** unaffected by: xMek1(F275A) [substitution]
    *** unaffected by: xMek1(D303A) [substitution]
    *** inhibited by: xMek1(M308A/I310A) [substitution]
    *** source: 19541618-Fig-1c
  *** xMek1[tAb] copptby[WB] xLamtor3[tAb] is detectable
    *** cells: CCL39 in BMS
    *** inhibited by: xMek1(del(270-307))"del-PRS" [substitution]
    *** source: 9733512-Fig-1b
  *** xMek1[tAb] copptby[WB] xLamtor3[tAb] is detectable
    *** cells: CCL39<xLamtor3><xMek1> in BMS
    *** inhibited by: xMek1(del(270-307))"dPRS" [substitution]
    *** inhibited by: xMek1(L274S) [substitution]
    *** source: 19541618-Fig-1b
  *** xMek1[tAb] copptby[WB] xRaf1[tAb] is decreased itpo xHras(G12V)"CA"
    *** cells: COS1 in BMS
    *** source: 11782426-Fig-4c,5
  *** xMek1[tAb]IP IVKA(Erk?)[32P-ATP] is detectable
    *** cells: mEFs<Ksr1~null><xKsr1><xMek1> in BMLS
    *** inhibited by: xMek1(M308A/I310A) [substitution]
    *** source: 19541618-Fig-S2
  *** xMek1[tAb]IP IVKA(Erk1)[32P-ATP] is increased itpo xMekk3
    *** cells: NIH3T3 in BMLS
    *** source: 9006902-Fig-3b
  *** xMek1[tAb]IP IVKA(Erk1)[32P-ATP] is unchanged itpo xMekk4
    *** cells: COS7 in BMS
    *** source: 9305639-Fig-8
  *** xMek1[tAb]IP IVKA(Erk2)[32P-ATP] is increased itpo (xCdc42(G12V)"CA" + xRaf1)
    *** cells: HEK293 in BMLS
    *** reqs: both [omissions]
    *** partially inhibited by: xPak1((165-544)/K298A)"DN" [addition]
    *** source: 9351825-Fig-5a,6c
  *** xMek1[tAb]IP IVKA(Erk2)[32P-ATP] is increased itpo (xRac2(G12V)"CA" + xRaf1)
    *** cells: HEK293 in BMLS
    *** reqs: both [omissions]
    *** partially inhibited by: xPak1((165-544)/K298A)"DN" [addition]
    *** source: 9351825-Fig-5a,6c
  *** xMek1[tAb]IP IVKA(Erk2)[32P-ATP] is increased itpo (xRhoa(Q63L)"CA" + xRaf1)
    *** cells: HEK293 in BMLS
    *** reqs: both [omissions]
    *** partially inhibited by: xPak1((165-544)/K298A)"DN" [addition]
    *** source: 9351825-Fig-5a,6c
  *** xMek1[tAb]IP IVKA(Erk2)[32P-ATP] is increased itpo xAsk1
    *** cells: COS7 in BMS
    *** source: 8974401-Fig-2a
  *** xMek1[tAb]IP IVKA(Erk2)[32P-ATP] is increased itpo xHras(G12V)"CA"
    *** cells: HEK293 in BMLS
    *** unaffected by: xPak1((165-544)/K298A)"DN" [addition]
    *** source: 9351825-Fig-5a,6c
  *** xMek1[tAb]IP IVKA(Erk2)[32P-ATP] is unchanged itpo xCdc42(G12V)"CA"
    *** cells: HEK293 in BMLS
    *** source: 9351825-Fig-5a
  *** xMek1[tAb]IP IVKA(Erk2)[32P-ATP] is unchanged itpo xRac2(G12V)"CA"
    *** cells: HEK293 in BMLS
    *** source: 9351825-Fig-5a
  *** xMek1[tAb]IP IVKA(Erk2)[32P-ATP] is unchanged itpo xRhoa(Q63L)"CA"
    *** cells: HEK293 in BMLS
    *** source: 9351825-Fig-5a
  *** xMek1[tAb]IP phos(S218/S222)[phosAb] is increased itpo (xRac1(Q61L)"CA" + xRaf1)
    *** cells: HEK293 in BMLS
    *** reqs: both [omissions]
    *** inhibited by: xRaf1(K375W)"KD" [substitution]
    *** inhibited by: xRaf1(S338A/S339C) [substitution]
    *** inhibited by: xRaf1(S338D/S339E) [substitution]
    *** source: 11948406-Fig-1b
  *** xMek1[tAb]IP phos(S218/S222)[phosAb] is increased itpo xHras(G12V)"CA"
    *** cells: HEK293 in BMLS
    *** unaffected by: xMek1(T292A) [substitution]
    *** unaffected by: xMek1(S298A) [substitution]
    *** unaffected by: xMek1(T292A/S298A) [substitution]
    *** source: 11948406-Fig-6b
  *** xMek1[tAb]IP phos(S218/S222)[phosAb] is increased itpo xHras(G12V)"CA"
    *** cells: rEFs in BMLS "in suspension"
    *** unaffected by: xMek1(K97A)"KD" [substitution]
    *** unaffected by: xMek1(S298A) [substitution]
    *** source: 17314031-Fig-2b
  *** xMek1[tAb]IP phos(S298)[phosAb] is decreased itpo (xHras(G12V)"CA" + xErk2)
    *** cells: COS1 in BMLS
    *** reqs: both [omissions]
    *** source: 14993270-Fig-3a
  *** xMek1[tAb]IP phos(S298)[phosAb] is increased itpo xFak1
    *** cells: mEFs<Fak1~null> in BMS "in suspension"
    *** inhibited by: xFak1(Y397F) [substitution]
    *** source: 12876277-Fig-6b
  *** xMek1[tAb]IP phos(S298)[phosAb] is increased itpo xHras(G12V)"CA"
    *** cells: rEFs in BMLS "in suspension"
    *** unaffected by: xMek1(K97A)"KD" [substitution]
    *** source: 17314031-Fig-2b
  *** xMek1[tAb]IP phos(S298)[phosAb] is unchanged itpo xHras
    *** cells: COS1 in BMLS
    *** source: 14993270-Fig-3a
  *** xMek1[tAb]IP phos(SMANS)[phosAb] is detectable
    *** cells: mEFs<Ksr1~null><xKsr1><xMek1> in BMLS
    *** inhibited by: xMek1(M308A/I310A) [substitution]
    *** source: 19541618-Fig-S2
*** Mek2--
  *** rMek2[Ab] boundby[WB] rIqGap1[Ab] is detectable
    *** cells: none
    *** enhanced by: rErk1 [addition]
    *** source: 16135787-Fig-9b
  *** rMek2[Ab] boundby[WB] rIqGap1[Ab] is detectable
    *** cells: none
    *** enhanced by: rErk2 [addition]
    *** source: 16135787-Fig-10a
  *** rMek2[Ab] boundby[WB] rIqGap1[GST] is detectable
    *** cells: none
    *** source: 16135787-Fig-1b
  *** xMek2[Ab] copptby[WB] IqGap1[Ab] is detectable
    *** cells: MCF7 in BMLS
    *** source: 16135787-Fig-2a
  *** Mek2[MS] copptby[WB] xKsr1[tAb] is detectable
    *** cells: COS in BMS
    *** source: 12932319-Fig-1a
  *** xMek2[tAb] copptby[WB] xKsr1[tAb] is detectable
    *** cells: mEFs<Ksr1~null><xKsr1><xMek2> in BMS
    *** inhibited by: xMek2(M316A/I318A) [substitution]
    *** source: 19541618-Fig-1c
  *** xMek2[tAb] copptby[WB] xLamtor3[tAb] is undetectable
    *** cells: CCL39 in BMS
    *** source: 9733512-Fig-1b
  *** xMek2[tAb]IP IVKA(Erk2)[32P-ATP] is increased itpo (xCdc42(G12V)"CA" + xRaf1)
    *** cells: HEK293 in BMLS
    *** reqs: both [omissions]
    *** source: 9351825-Fig-5b
  *** xMek2[tAb]IP IVKA(Erk2)[32P-ATP] is increased itpo (xRac2(G12V)"CA" + xRaf1)
    *** cells: HEK293 in BMLS
    *** reqs: both [omissions]
    *** source: 9351825-Fig-5b
  *** xMek2[tAb]IP IVKA(Erk2)[32P-ATP] is increased itpo (xRhoa(Q63L)"CA" + xRaf1)
    *** cells: HEK293 in BMLS
    *** reqs: both [omissions]
    *** source: 9351825-Fig-5b
  *** xMek2[tAb]IP IVKA(Erk2)[32P-ATP] is increased itpo xHras(G12V)"CA"
    *** cells: HEK293 in BMLS
    *** source: 9351825-Fig-5b
  *** xMek2[tAb]IP IVKA(Erk2)[32P-ATP] is increased itpo xMekk1(CatDom)
    *** cells: HEK293 in BMS
    *** source: 7624324-Fig-4[tr]
  *** xMek2[tAb]IP IVKA(Erk2)[32P-ATP] is unchanged itpo xCdc42(G12V)"CA"
    *** cells: HEK293 in BMLS
    *** source: 9351825-Fig-5b
  *** xMek2[tAb]IP IVKA(Erk2)[32P-ATP] is unchanged itpo xRac2(G12V)"CA"
    *** cells: HEK293 in BMLS
    *** source: 9351825-Fig-5b
  *** xMek2[tAb]IP IVKA(Erk2)[32P-ATP] is unchanged itpo xRhoa(Q63L)"CA"
    *** cells: HEK293 in BMLS
    *** source: 9351825-Fig-5b
  *** xMek2[tAb]IP phos[32Pi] is increased itpo xMekk1(CatDom)
    *** cells: HEK293 in BMS
    *** source: 7624324-Fig-4[tl]
  *** Mek5[MS] copptby[WB] xMekk3[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 18206350-Fig-1b
  *** xMek5[tAb]IP phos(sitenr)[phosAb] is increased itpo xTpl2
    *** cells: NIH3T3 in BMS
    *** source: 10669751-Fig-6
  *** Mek12s[Ab] copptby[WB] Braf[tAb] is detectable
    *** cells: mEFs<Ksr1~null><xKsr1> in BMLS
    *** reqs: xKsr1 [omission]
    *** source: 19541618-Fig-2b
  *** Mek12s[Ab] copptby[WB] Raf1[tAb] is undetectable
    *** cells: mEFs<Ksr1~null><xKsr1> in BMLS
    *** unaffected by: xKsr1 [omission]
    *** source: 19541618-Fig-2b
  *** Mek12s[Ab] copptby[WB] xBraf[tAb] is detectable
    *** cells: HEK293<xBraf> in BMS
    *** unaffected by: xRaf1(mnr)"BXB" [addition]
    *** comment: coppt Mek12s is phosed unless xBraf is substituted with xBraf(mnr)"KD"
    *** comment: addition of xRaf1(mnr)"BXB" can restore Mek12s-phos
    *** source: 18332145-Fig-3b
  *** Mek12s[Ab] copptby[WB] xBraf[tAb] is undetectable
    *** cells: CCL39<xKsr1><xBraf><xRaf1> in BMS
    *** source: 19541618-Fig-2a
  *** Mek12s[Ab] copptby[WB] xBrap[tAb] is detectable
    *** cells: HEK293<xKsr1><xBrap> in BMS
    *** reqs: xKsr1 [omission]
    *** source: 18332145-Fig-1b
  *** Mek12s[Ab] copptby[WB] xKsr1[Ab] is detectable
    *** cells: HEK293<xKsr1> in BMS
    *** unaffected by: xKsr1(540-873)"mCterm" [substitution]
    *** source: 18332145-Fig-1a
  *** Mek12s[Ab] copptby[WB] xKsr1[tAb] is detectable
    *** cells: CCL39<xKsr1><xBraf><xRaf1> in BMS
    *** source: 19541618-Fig-2a
  *** Mek12s[Ab] copptby[WB] xKsr1[tAb] is detectable
    *** cells: COS in BMLS
    *** unaffected by: Egf (5 min) [stim]
    *** source: 11741534-Fig-1
  *** Mek12s[Ab] copptby[WB] xKsr1[tAb] is detectable
    *** cells: COS in BMLS
    *** unaffected by: Egf (5 min) [stim]
    *** unaffected by: xKsr1(S392A) [substitution]
    *** unaffected by: xKsr1(S392A/S297A) [substitution]
    *** source: 11741534-Fig-5b
  *** Mek12s[Ab] copptby[WB] xKsr1[tAb] is detectable
    *** cells: HEK293<xKsr1> in BMS
    *** unaffected by: xBrap [addition]
    *** comment: Mek12s IP is phosed on SMANS site
    *** comment: MEk12s IP phos is decreased itpo xBrap
    *** source: 18332145-Fig-1a
  *** Mek12s[Ab] copptby[WB] xKsr1[tAb] is detectable
    *** cells: HEK293<xRaf1><xKsr1> in BMS
    *** unaffected by: xBrap [addition]
    *** source: 18332145-Fig-4c
  *** Mek12s[Ab] copptby[WB] xKsr1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xKsr1(C857Y) [substitution]
    *** source: 10409742-Fig-2b,2c
  *** Mek12s[Ab] copptby[WB] xKsr1[tAb] is detectable
    *** cells: mEFs<Ksr1~null><xKsr1><xMek1> in BMLS
    *** inhibited by: xKsr1(530-873)"mouseCterm" [substitution]
    *** unaffected by: xKsr1(1-529)"mouseNterm" [substitution]
    *** unaffected by: xKsr1(L58G/R57S) [substitution]
    *** unaffected by: xKsr1(mnr)"AxAp" [substitution]
    *** inhibited by: xKsr1(C809Y)"hC857Y" [substitution]
    *** source: 19541618-Fig-3a
  *** Mek12s[Ab] copptby[WB] xKsr1[tAb] is detectable
    *** cells: NIH3T3 in BMLS
    *** unaffected by: Pdgf (5 min) [stim]
    *** unaffected by: Okadaic-acid [addition]
    *** source: 12932319-Fig-3c
  *** Mek12s[Ab] copptby[WB] xRaf1[tAb] is undetectable
    *** cells: CCL39<xKsr1><xBraf><xRaf1> in BMS
    *** source: 19541618-Fig-2a
  *** Mek12s[Ab] copptby[WB] Ywhas[Ab] is detectable
    *** cells: HEK293T<xKsr1> in BMS
    *** inhibited by: xKsr1(C857Y)"Ywhas-binding-mut" [addition]
    *** source: 10409742-Fig-2e
  *** Mek12s[Ab] infraction(DRM)[WB] is detectable
    *** cells: mEFs<Lamtor1~null><xLamtor1> in BMLS
    *** partially reqs: xLamtor1 [omission]
    *** source: 19177150-Fig-6e
  *** Mek12s[Ab] infraction(membrane)[WB] is increased itpo xKsr1
    *** cells: HEK293T in BMS
    *** inhibited by: xKsr1(C857Y) [substitution]
    *** inhibited by: xKsr1(del(548-921)) [substitution]
    *** source: 10409742-Fig-3b
  *** Mek12s[phosAb] phos(S218/S222)[phosAb] is detectable
    *** cells: MCF7 in BMLS
    *** reqs: IqGap1 [RNAi]
    *** source: 16135787-Fig-4a
  *** Mek12s[phosAb] phos(sitenr)[phosAb] is detectable
    *** cells: mEFs<Lamtor1~null><xLamtor1> in BMS
    *** partially reqs: xLamtor1 [omission]
    *** source: 19177150-Fig-6a
  *** Mek12s[phosAb] phos(sitenr)[phosAb] is increased itpo xHras(Q61L)"CA"
    *** cells: COS in BMLS
    *** enhanced by: xBraf [addition]
    *** unaffected by: xBraf(T599A/S602A) [addition]
    *** source: 15632082-Fig-5b
  *** Mek12s[phosAb] phos(sitenr)[phosAb] is increased itpo xHras(Q61L)"CA"
    *** cells: PC6 in BMLS
    *** source: 15632082-Fig-1c
  *** Mek12s[phosAb] phos(sitenr)[phosAb] is increased itpo xMekk3
    *** cells: HEK293EBNA in BMS
    *** inhibited by: xMekk3(K391M)"KD" [substitution]
    *** inhibited by: xMekk3(S526A) [substitution]
    *** inhibited by: xMekk3(T530A) [substitution]
    *** unaffected by: xMekk3(T516A) [substitution]
    *** unaffected by: xMekk3(T528A) [substitution]
    *** unaffected by: xMekk3(T511A) [substitution]
    *** unaffected by: xMekk3(T520A) [substitution]
    *** unaffected by: xMekk3(T522A) [substitution]
    *** source: 16407301(D)
  *** Mek12s[phosAb] phos(sitenr)[phosAb] is increased itpo xRit1(Q79L)"CA"
    *** cells: COS in BMLS
    *** enhanced by: xBraf [addition]
    *** partially inhibited by: xBraf(T599A/S602A) [addition]
    *** source: 15632082-Fig-5b
  *** Mek12s[phosAb] phos(sitenr)[phosAb] is increased itpo xRit1(Q79L)"CA"
    *** cells: PC6 in BMLS
    *** inhibited by: xRit1(WT) [substitution]
    *** source: 15632082-Fig-1c
  *** Mek12s[phosAb] phos(SMANS)[phosAb] is detectable
    *** cells: HEPG2 in BMLS "plated on collagen"
    *** unaffected by: Gefitinib [cotreatment]
    *** partially inhibited by: PD325901 [cotreatment]
    *** unaffected by: BMS345541 [cotreatment]
    *** unaffected by: PHA818637 [cotreatment]
    *** unaffected by: ZSTK474 [cotreatment]
    *** source: 19953085-Fig-S1
  *** Mek12s[phosAb] phos(SMANS)[phosAb] is detectable
    *** cells: NIH3T3<xBraf(E501G)> in BMLS
    *** enhanced by: xBraf(E501G/S151A/S401A/S750A/T753A) [substitution]
    *** source: 19933846-Fig-8a
  *** Mek12s[phosAb] phos(SMANS)[phosAb] is detectable
    *** cells: NIH3T3<xBraf(S467A)> in BMLS
    *** enhanced by: xBraf(S467A/S151A/S401A/S750A/T753A) [substitution]
    *** source: 19933846-Fig-8a
  *** Mek12s[phosAb] phos(SMANS)[phosAb] is detectable
    *** cells: NIH3T3<xRaf1(T260A/T274A/S320A/S443A)> in BMLS
    *** inhibited by: xRaf1 [substitution]
    *** enhanced by: xRaf1(P261S/T260A/T274A/S320A/S443A) [substitution]
    *** enhanced by: xRaf1(L613V/T260A/T274A/S320A/S443A) [substitution]
    *** source: 19933846-Fig-8a
  *** Mek12s[phosAb] phos(SMANS)[phosAb] is increased itpo xBraf
    *** cells: HEK293 in BMS
    *** enhanced by: xBraf(V600E) [substitution]
    *** enhanced by: xBraf(S365A) [substitution]
    *** inhibited by: xBraf(S729A) [substitution]
    *** inhibited by: xBraf(S365A/S729A) [substitution]
    *** source: 16702958-Fig-3d
  *** Mek12s[phosAb] phos(SMANS)[phosAb] is increased itpo xBraf
    *** cells: HEK293 in BMS
    *** enhanced by: xBraf(V600E) [substitution]
    *** enhanced by: xBraf(S365A) [substitution]
    *** unaffected by: xBraf(S365A/S446A/S447A) [substitution]
    *** unaffected by: xBraf(S365A/S446A/S447A/D448A/D449A) [substitution]
    *** source: 16702958-Fig-3c
  *** Mek12s[phosAb] phos(SMANS)[phosAb] is increased itpo xKsr1
    *** cells: mEFs<Ksr1~null> in BMLS
    *** source: 19541618-Fig-2c
  *** Mek12s[phosAb] phos(SMANS)[phosAb] is increased itpo xRin1(Q78L)
    *** cells: PC6 in BMLS
    *** enhanced by: xBraf [addition]
    *** source: 16157584-Fig-6f
  *** Mek12s[phosAb] phos(SMANS)[phosAb] is increased itpo xRin1(Q78L)
    *** cells: PC6 in BMLS
    *** enhanced by: xBraf [addition]
    *** source: 16157584-Fig-6g
  *** Mek12s[phosAb] phos(SMANS)[phosAb] is increased itpo xRin1(Q78L)
    *** cells: PC6<xBraf> in BMLS
    *** inhibited by: PD98059 [pretreatment]
    *** source: 16157584-Fig-6g
  *** Mek12s[phosAb] phos(SMANS)[phosAb] is increased itpo xRin1(Q78L)
    *** cells: PC6<xBraf> in BMLS
    *** unaffected by: SB203580 [pretreatment]
    *** source: 16157584-Fig-6f
*** Mekk1--
  *** rMekk1(30-220)[32P] phos[32P-ATP] is increased by rPak1(232-544)
    *** cells: none
    *** comment: phos-site was determined to be Mekk1-S67 by MS
    *** source: 12228228-Fig-1b,2
  *** rMekk1(30-220)[phosAb] phos(S67)[phosAb] is increased by rPak1(232-544)
    *** cells: none
    *** source: 12228228-Fig-3d
  *** xMekk1(CatDom)"CA"[tAb] copptby[WB] xJnk1[tAb] is detectable
    *** cells: COS1 in BMS
    *** inhibited by: xMkk4 [addition]
    *** source: 9808624-Fig-7a
  *** xMekk1(CatDom)[Ab] snaggedby[WB] rRhoa{GDP}[GST] is undetectable
    *** cells: COS in BMS
    *** source: 9305638-Fig-6a
  *** xMekk1(CatDom)[Ab] snaggedby[WB] rRhoa{GTPgS}[GST] is undetectable
    *** cells: COS in BMS
    *** source: 9305638-Fig-6a
  *** xMekk1(mnr)"C"[Ab] copptby[WB] xApc[Ab] is detectable
    *** cells: HEK293T<xAxin1><xMekk1(mnr)"C"><xApc> in BMS
    *** source: 11408485-Fig-5b
  *** xMekk1(mnr)"C"[Ab] copptby[WB] xAxin1[tAb] is detectable
    *** cells: HEK293T<xAxin1><xMekk1(mnr)"C"> in BMS
    *** inhibited by: xGsk3b [addition]
    *** inhibited by: xGsk3b(Y216F) [addition]
    *** unaffected by: xGsk3b(K83M) [addition]
    *** source: 11408485-Fig-2
  *** xMekk1(mnr)"C"[Ab] copptby[WB] xAxin1[tAb] is detectable
    *** cells: HEK293T<xAxin1><xMekk1(mnr)"C"><xApc> in BMS
    *** source: 11408485-Fig-5b
  *** xMekk1(mnr)"C"[Ab] copptby[WB] xGsk3b[tAb] is undetectable
    *** cells: HEK293T<xGsk3b><xMekk1(mnr)"C"> in BMS
    *** source: 11408485-Fig-2
  *** Mekk1[Ab] copptby[WB] Axin1[Ab] is detectable
    *** cells: LS174T in BMS
    *** source: 20128690-Fig-1c
  *** Mekk1[Ab] copptby[WB] Map4k2[Ab] is detectable
    *** cells: RAMOS in BMS
    *** source: 11784851(D)
  *** Mekk1[Ab] copptby[WB] xMap4k2[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 9712898-Fig-1a
  *** Mekk1[Ab] infraction(DRM)[WB] is increased itpo xTraf2
    *** cells: HEK293T in BMLS
    *** source: 12370254-Fig-5b
  *** xMekk1[Ab] snaggedby[WB] rRhoa{GDP}[GST] is undetectable
    *** cells: COS in BMS
    *** source: 9305638-Fig-6e
  *** xMekk1[Ab] snaggedby[WB] rRhoa{GTPgS}[GST] is undetectable
    *** cells: COS in BMS
    *** source: 9305638-Fig-6e
  *** Mekk1[Ab]IP ubiq[UbAb] is increased by (rUbiq + rUbe1 + rUbe2d2)
    *** cells: none
    *** IPfrom: mSpBCs in BMS "treated with anti-Cd40 (times)"
    *** comment: ubiq required IP from anti-Cd40 treated cells
    *** comment: ubiq varied with treatment times: 0 10++ 20++ 60+ min
    *** source: 17143273-Fig-4c
  *** Mekk1[Ab]IP ubiq[UbAb] is increased by (rUbiq(K48R) + rUbe1 + rUbe2d2)
    *** cells: none
    *** IPfrom: mSpBCs in BMS "treated with anti-Cd40 (10 min)"
    *** comment: ubiq required IP from anti-Cd40 treated cells
    *** unaffected by: rUbiq(K63R) [substitution]
    *** source: 17143273-Fig-S8b
  *** xMekk1[tAb] copptby[WB] Erk2[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 10969079-Fig-7b
  *** xMekk1[tAb] oligomerization[2TagPpt] is increased itpo xMap4k2
    *** cells: HEK293 in BMS
    *** source: 11784851(D)
  *** xMekk1[tAb]IP IVKA(auto)[32P-ATP] is increased itpo xMap4k2
    *** cells: HEK293 in BMS
    *** source: 11784851(D)
  *** xMekk1[tAb]IP IVKA(auto)[32P-ATP] is increased itpo xTraf2
    *** cells: HEK293 in BMS
    *** source: 11784851-Fig-5a
  *** xMekk1[tAb]IP IVKA(Mkk4)[32P-ATP] is increased itpo xMap4k2
    *** cells: HEK293 in BMS
    *** source: 11784851(D)
  *** xMekk1[tAb]IP IVKA(Mkk4)[32P-ATP] is increased itpo xTraf2
    *** cells: HEK293 in BMS
    *** source: 11784851-Fig-5a
  *** xMekk1[tAb]IP ubiq[tUbAb] is detectable
    *** cells: A20<xUbiq> in BMS
    *** partially inhibited by: xMekk1(D1368A) [substitution]
    *** source: 17143273-Fig-S8c
  *** xMekk1[tAb]IP ubiq[tUbAb] is detectable
    *** cells: HEK293<xUbiq> in BMS
    *** partially inhibited by: xMekk1(D1368A) [substitution]
    *** source: 17143273-Fig-S8c
*** Mekk2--
  *** xMekk2[tAb]IP IVKA(Mkk7)[32P-ATP] is decreased itpo xSin1
    *** cells: COS1 in BMS
    *** source: 15988011-Fig-3b
  *** rMekk3 IVKA(peptide)[32P-ATP] is increased by rSgk1{act}
    *** cells: none
    *** inhibited by: rMekk3(S166A/S337A) [substitution]
    *** source: 12761204-Fig-3
*** Mekk3--
  *** xMekk3(CatDom)[Ab] snaggedby[WB] rCdc42{GDP}[GST] is undetectable
    *** cells: COS in BMS
    *** source: 9305638-Fig-6a
  *** xMekk3(CatDom)[Ab] snaggedby[WB] rCdc42{GTPgS}[GST] is undetectable
    *** cells: COS in BMS
    *** source: 9305638-Fig-6a
  *** xMekk3(CatDom)[Ab] snaggedby[WB] rRac1{GDP}[GST] is undetectable
    *** cells: COS in BMS
    *** source: 9305638-Fig-6a
  *** xMekk3(CatDom)[Ab] snaggedby[WB] rRac1{GTPgS}[GST] is undetectable
    *** cells: COS in BMS
    *** source: 9305638-Fig-6a
  *** xMekk3(CatDom)[Ab] snaggedby[WB] rRhoa{GDP}[GST] is undetectable
    *** cells: COS in BMS
    *** source: 9305638-Fig-6a
  *** xMekk3(CatDom)[Ab] snaggedby[WB] rRhoa{GTPgS}[GST] is undetectable
    *** cells: COS in BMS
    *** source: 9305638-Fig-6a
  *** rMekk3[32P] phos[32P-ATP] is increased by rSgk1{act}
    *** cells: none
    *** inhibited by: rMekk3(S166A/S337A) [substitution]
    *** source: 12761204-Fig-1a
  *** xMekk3[phosAb] phos(S526)[phosAb] is decreased itpo xTak1
    *** cells: HEK293 in BMS
    *** reversed by: xTab1 [addition]
    *** source: 16260783-Fig-5a
  *** xMekk3[phosAb] phos(S526)[phosAb] is decreased itpo xTak1
    *** cells: HEK293 in BMS
    *** source: 16260783-Fig-4d
  *** xMekk3[phosAb] phos(S526)[phosAb] is decreased itpo xTak1(K63A)"KD"
    *** cells: HEK293 in BMS
    *** unaffected by: xTab1 [addition]
    *** source: 16260783-Fig-5a
  *** xMekk3[phosAb] phos(S526)[phosAb] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xTak1 [addition]
    *** inhibited by: xTak1(K63A)"KD" [addition]
    *** source: 16260783-Fig-4a
  *** xMekk3[phosAb] phos(S526)[phosAb] is increased itpo xTraf6
    *** cells: HEK293T in BMS
    *** partially inhibited by: xTraf6(110-522)"T6dR" [substitution]
    *** inhibited by: xTraf6(260-522)"T6dRZ" [substitution]
    *** inhibited by: xTraf6(1-288)"T6dCT" [substitution]
    *** inhibited by: xTraf6(1-348)"T6dT" [substitution]
    *** source: 19843958-Fig-6b
  *** xMekk3[phosAb] phos(S526)[phosAb] is unchanged itpo xMekk2
    *** cells: HEK293 in BMS
    *** unaffected by: xMekk2(K395M)"KD" [substitution]
    *** source: 16260783-Fig-4d
  *** xMekk3[phosAb] phos(S526)[phosAb] is unchanged itpo xTab1
    *** cells: HEK293 in BMS
    *** source: 16260783-Fig-5a
  *** xMekk3[phosAb] phos(S526)[phosAb] is unchanged itpo xTpl2
    *** cells: HEK293 in BMS
    *** source: 16260783-Fig-4d
  *** xMekk3[tAb] copptby[WB] xTak1[Ab] is decreased itpo xTab1
    *** cells: HEK293T in BMS
    *** source: 18206350-Fig-6a
  *** xMekk3[tAb] oligomerization[2TagPpt] is increased itpo xTraf6
    *** cells: HEK293T in BMS
    *** unaffected by: xTraf6(110-522)"T6dR" [substitution]
    *** inhibited by: xTraf6(260-522)"T6dRZ" [substitution]
    *** inhibited by: xTraf6(1-348)"T6dT" [substitution]
    *** source: 19843958-Fig-6c
  *** xMekk3[tAb] phos[WBMS-PPase] is decreased itpo xTak1
    *** cells: HEK293T in BMS
    *** reversed by: xTab1 [addition]
    *** source: 18206350-Fig-4a
  *** xMekk3[tAb] phos[WBMS-PPase] is decreased itpo xTak1
    *** cells: HEK293T in BMS
    *** source: 18206350-Fig-3b
  *** xMekk3[tAb] phos[WBMS-PPase] is increased itpo (xTak1 + xTab1)
    *** cells: HEK293T in BMS
    *** reqs: xTab1 [omission]
    *** inhibited by: xMekk3(S526A/K391M) [substitution]
    *** source: 18206350-Fig-6a
  *** xMekk3[tAb]IP IVKA(auto)[32P-ATP] is unchanged itpo xMap4k2
    *** cells: HEK293 in BMS
    *** source: 11784851(D)
  *** xMekk3[tAb]IP IVKA(auto)[32P-ATP] is unchanged itpo xTraf2
    *** cells: HEK293 in BMS
    *** source: 11784851(D)
  *** xMekk3[tAb]IP IVKA(Mkk4)[32P-ATP] is unchanged itpo xMap4k2
    *** cells: HEK293 in BMS
    *** source: 11784851(D)
  *** xMekk3[tAb]IP IVKA(Mkk4)[32P-ATP] is unchanged itpo xTraf2
    *** cells: HEK293 in BMS
    *** source: 11784851(D)
  *** xMekk3[tAb]IP ubiq[tUbAb] is increased itpo xTraf6
    *** cells: HEK293T<xUbiq(K63only)> in BMS
    *** comment: lysates were boiled to remove noncovalently attached proteins before IP
    *** inhibited by: xTraf6(110-522)"T6dR" [substitution]
    *** inhibited by: xTraf6(260-522)"T6dRZ" [substitution]
    *** source: 19843958-Fig-S16a
*** Mekk4--
  *** xMekk4(CatDom)[Ab] snaggedby[WB] rCdc42{GDP}[GST] is detectable
    *** cells: COS in BMS
    *** source: 9305638-Fig-6a
  *** xMekk4(CatDom)[Ab] snaggedby[WB] rCdc42{GTPgS}[GST] is detectable
    *** cells: COS in BMS
    *** source: 9305638-Fig-6a
  *** xMekk4(CatDom)[Ab] snaggedby[WB] rRac1{GDP}[GST] is detectable
    *** cells: COS in BMS
    *** source: 9305638-Fig-6a
  *** xMekk4(CatDom)[Ab] snaggedby[WB] rRac1{GTPgS}[GST] is detectable
    *** cells: COS in BMS
    *** source: 9305638-Fig-6a
  *** xMekk4(CatDom)[Ab] snaggedby[WB] rRhoa{GDP}[GST] is detectable
    *** cells: COS in BMS
    *** source: 9305638-Fig-6a
  *** xMekk4(CatDom)[Ab] snaggedby[WB] rRhoa{GTPgS}[GST] is detectable
    *** cells: COS in BMS
    *** source: 9305638-Fig-6a
  *** rMekk4[35S] boundby[WB] rGadd45b[GST] is detectable
    *** cells: none
    *** source: 14743220-Fig-1c
  *** Mekk4[Ab] copptby[WB] Axin1[Ab] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xAxin1(210-338)"Mekk1-binding-mut" [addition]
    *** source: 12878610-Fig-3
  *** Mekk4[Ab] copptby[WB] Mekk1[Ab] is undetectable
    *** cells: HEK293T in BMS
    *** source: 12878610-Fig-3
  *** xMekk4[Ab] snaggedby[WB] rCdc42{GDP}[GST] is detectable
    *** cells: COS in BMS
    *** source: 9305638-Fig-6a
  *** xMekk4[Ab] snaggedby[WB] rCdc42{GTPgS}[GST] is detectable
    *** cells: COS in BMS
    *** source: 9305638-Fig-6a
  *** xMekk4[Ab] snaggedby[WB] rRhoa{GDP}[GST] is detectable
    *** cells: COS in BMS
    *** source: 9305638-Fig-6a
  *** xMekk4[Ab] snaggedby[WB] rRhoa{GTPgS}[GST] is detectable
    *** cells: COS in BMS
    *** source: 9305638-Fig-6a
  *** xMekk4[tAb] copptby[WB] xGadd45b[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 14743220-Fig-1a
*** Merlin--
  *** xMerlin[tAb] copptby[WB] xMlk3[tAb] is detectable
    *** cells: HEK293 in BMLS
    *** unaffected by: Serum (10 min) [stim]
    *** source: 16537381-Fig-4b
  *** xMerlinb[tAb] copptby[WB] xMlk3[GST] is detectable
    *** cells: HEK293<xMlk3><xMerlinb> in BMS
    *** inhibited by: xMerlinb(S518D) [substitution]
    *** unaffected by: xMerlinb(S518A) [substitution]
    *** source: 20890305-Fig-2d
  *** Mitf[Ab] copptby[WB] Pias3[Ab] is detectable
    *** cells: mBMMastCs in BMS "IL3-deprived"
    *** inhibited by: kMitf(mnr)"delZip" [knockin]
    *** source: 15572665-Fig-6c
  *** xMitf[tAb] copptby[WB] xPias3[tAb] is detectable
    *** cells: NIH3T3<xStat3(Y705F)> in BMS
    *** inhibited by: xStat3(C661A/C663N) [substitution]
    *** source: 15572665-Fig-4a
  *** xMitf[tAb] locatedin(nucleus)[IHC] is detectable
    *** cells: B16<xPias3><xStat3> in BMS
    *** source: 15572665-Fig-7a
  *** xMitf[tAb] locatedin(nucleus)[IHC] is detectable
    *** cells: NIH3T3<xPias3><xStat3> in BMS
    *** source: 15572665-Fig-5a
*** Mkk3--
  *** rMkk3[32P] phos[32P-ATP] is increased by rMekk3
    *** cells: none
    *** inhibited by: rMkk3(S218A) [substitution]
    *** source: 12761204-Fig-2
  *** Mkk3[Ab]IP IVKA(P38a,Atf2)[32P-ATP] is increased itpo xMekk1
    *** cells: COS1 in BMS
    *** source: 9639566-Fig-3a
  *** Mkk3[Ab]IP IVKA(P38a,Atf2)[32P-ATP] is increased itpo xMlk2
    *** cells: COS1 in BMS
    *** source: 9639566-Fig-3a
  *** Mkk3[Ab]IP IVKA(P38a,Atf2)[32P-ATP] is increased itpo xMlk2
    *** cells: KB in BMS
    *** source: 9639566-Fig-3c
  *** xMkk3[Ab]IP IVKA(P38a)[32P-ATP] is detectable
    *** cells: COS1 in BMS
    *** enhanced by: xMkk6(S189E/T193E) [substitution]
    *** source: 8622669-Fig-1a
  *** rMkk3[GST] IVKA(P38a,Atf2)[32P-ATP] is unchanged by xMekk3[tAb]IP
    *** cells: none
    *** IPfrom: COS7 in BMS
    *** source: 10347227-Fig-3a
  *** Mkk3[phosAb] phos(sitenr)[phosAb] is decreased itao Traf6 [RNAi]
    *** cells: mMesangialCells in BMLS
    *** times: 0+ 5++ 15++ 30++ min
    *** source: 19556242-Fig-7b
  *** xMkk3[tAb] copptby[WB] xGadd45b[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 14743220-Fig-1a
  *** xMkk3[tAb] copptby[WB] xTab1[GST] is undetectable
    *** cells: HEK293 in BMS
    *** source: 14592977-Fig-1
  *** xMkk3[tAb] copptby[WB] xTaok2[tAb] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: rTaok2(1-320)"CA" [substitution]
    *** inhibited by: rTaok2(D169A) [substitution]
    *** source: 10497253-Fig-3b
  *** xMkk3[tAb]IP IVKA(P38?)[32P-ATP] is increased itpo xMekk1(CatDom)"CA"
    *** cells: COS1 in BMS
    *** source: 9808624-Fig-2a
  *** xMkk3[tAb]IP IVKA(P38?)[32P-ATP] is increased itpo xMekk4
    *** cells: COS7 in BMS
    *** source: 9305639-Fig-8
  *** xMkk3[tAb]IP IVKA(P38a)[32P-ATP] is increased itpo xAsk1
    *** cells: COS7 in BMS
    *** source: 8974401-Fig-2a
  *** xMkk3[tAb]IP phos(sitenr)[phosAb] is increased itpo xMekk4
    *** cells: COS7 in BMS
    *** source: 9305639-Fig-8
  *** xMkk3[tAb]IP phos(sitenr)[phosAb] is increased itpo xMlk3
    *** cells: HELA in BMS
    *** inhibited by: xMkk3(S189A/T193L) [substitution]
    *** source: 9003778-Fig-3b
*** Mkk4--
  *** rMkk4(K167R)[32P] phos[32P-ATP] is unchanged by xRaf1(del(66-303))"CA"[tAb]IP
    *** cells: none
    *** comment: xRaf1(del(66-303))"CA"IP is from HEK293 cells
    *** source: 10232608-Fig-5b
  *** Mkk4[Ab]IP IVKA(Jnk1,Atf2)[32P-ATP] is increased itpo xMlk2
    *** cells: COS1 in BMS
    *** source: 9639566-Fig-1a
  *** Mkk4[Ab]IP IVKA(Jnk1,Atf2)[32P-ATP] is increased itpo xMlk2
    *** cells: KB in BMS
    *** source: 9639566-Fig-1d
  *** rMkk4[GST] IVKA(Jnk1,Jun)[32P-ATP] is unchanged by xMekk3[tAb]IP
    *** cells: COS7 in BMS
    *** source: 10347227-Fig-3a
  *** Mkk4[phosAb] phos(T261)[phosAb] is increased itpo xRac1(G12V)
    *** cells: HEPG2 in BMS
    *** source: 11335711-Fig-5a
  *** Mkk4[phosAb] phos(T261)[phosAb] is unchanged itpo xCdc42(G12V)"CA"
    *** cells: HEK293 in BMS
    *** source: 10862766(D)
  *** rMkk4[tAb] boundby[WB] rPosh[GST] is undetectable
    *** cells: none
    *** source: 16571722-Fig-1a
  *** xMkk4[tAb] copptby[WB] xGadd45b[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 14743220-Fig-1a
  *** xMkk4[tAb] copptby[WB] xPosh[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 12514131-Fig-4d
  *** xMkk4[tAb]IP IVKA(Jnk1,Jun)[32P-ATP] is increased itpo xCdc42(G12V)"CA"
    *** cells: HELA in BMS
    *** source: 9535930-Fig-6a
  *** xMkk4[tAb]IP IVKA(Jnk1,Jun)[32P-ATP] is increased itpo xHpk1
    *** cells: COS7 in BMS
    *** source: 9891090-Fig-8
  *** xMkk4[tAb]IP IVKA(Jnk1,Jun)[32P-ATP] is increased itpo xHras(Q61L)"CA"
    *** cells: HELA in BMS
    *** source: 9535930-Fig-6a
  *** xMkk4[tAb]IP IVKA(Jnk1,Jun)[32P-ATP] is increased itpo xMap3k12
    *** cells: COS7 in BMS
    *** source: 9891090-Fig-7
  *** xMkk4[tAb]IP IVKA(Jnk1,Jun)[32P-ATP] is increased itpo xMap4k5
    *** cells: COS7 in BMS
    *** source: 9891090-Fig-8
  *** xMkk4[tAb]IP IVKA(Jnk1,Jun)[32P-ATP] is increased itpo xMekk3
    *** cells: COS7 in BMS
    *** source: 9891090-Fig-7
  *** xMkk4[tAb]IP IVKA(Jnk1,Jun)[32P-ATP] is increased itpo xRac1(G12V)"CA"
    *** cells: HELA in BMS
    *** source: 9535930-Fig-6a
  *** xMkk4[tAb]IP IVKA(Jnk1)[32P-ATP] is increased itpo xMekk3
    *** cells: NIH3T3 in BMLS
    *** source: 9006902-Fig-3a
  *** xMkk4[tAb]IP IVKA(Jnk1)[32P-ATP] is unchanged itpo xRaf1(del(66-303))"CA"
    *** cells: NIH3T3 in BMLS
    *** source: 9006902-Fig-3a
  *** xMkk4[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMap4k4
    *** cells: HEK293 in BMS
    *** source: 9135144-Fig-5b
  *** xMkk4[tAb]IP IVKA(P38a)[32P-ATP] is increased itpo xAsk1
    *** cells: COS7 in BMS
    *** source: 8974401-Fig-2a
  *** xMkk4[tAb]IP phos(sitenr)[phosAb] is increased itpo xTpl2
    *** cells: NIH3T3 in BMS
    *** source: 10669751-Fig-6
*** Mkk6--
  *** rMkk6[32P] phos[32P-ATP] is unchanged by rRaf1
    *** cells: none
    *** source: 8663074-Fig-3a
  *** Mkk6[Ab]IP IVKA(P38a,Atf2)[32P-ATP] is increased itpo xMekk1
    *** cells: COS1 in BMS
    *** source: 9639566-Fig-3a
  *** Mkk6[Ab]IP IVKA(P38a,Atf2)[32P-ATP] is increased itpo xMlk2
    *** cells: COS1 in BMS
    *** source: 9639566-Fig-3a
  *** Mkk6[Ab]IP IVKA(P38a,Atf2)[32P-ATP] is increased itpo xMlk2
    *** cells: KB in BMS
    *** source: 9639566-Fig-3c
  *** rMkk6[GST] IVKA(P38a,Atf2)[32P-ATP] is increased by xMekk2[tAb]IP
    *** cells: COS7 in BMS
    *** source: 10347227-Fig-4a
  *** xMkk6[tAb]IP IVKA(auto)[32P-ATP] is increased itpo xMekk2
    *** cells: COS7 in BMS
    *** source: 10347227-Fig-1a
  *** xMkk6[tAb]IP IVKA(P38?)[32P-ATP] is increased itpo xMekk1(CatDom)
    *** cells: COS1 in BMS
    *** source: 9808624-Fig-2a
  *** xMkk6[tAb]IP IVKA(P38s,Atf2)[32P-ATP] is increased itpo xMekk2
    *** cells: COS7 in BMS
    *** source: 10347227-Fig-2a
  *** xMkk6[tAb]IP IVKA(P38s)[32P-ATP] is increased itpo xMekk2
    *** cells: COS7 in BMS
    *** source: 10347227-Fig-1b
  *** xMkk6[tAb]IP phos(sitenr)[phosAb] is increased itpo xTpl2
    *** cells: NIH3T3 in BMS
    *** source: 10669751-Fig-6
*** Mkk7
  *** rMkk7[35S] boundby[WB] rGadd45b[GST] is detectable
    *** cells: none
    *** source: 14743220-Fig-1c
  *** Mkk7[Ab] copptby[WB] Jip1[Ab] is detectable
    *** cells: PC12 in BMS "neuronally differentiated"
    *** source: 16571722-Fig-2b
  *** Mkk7[Ab]IP IVKA(Jnk1,Atf2)[32P-ATP] is increased itpo xMlk2
    *** cells: COS1 in BMS
    *** source: 9639566-Fig-1a
  *** Mkk7[Ab]IP IVKA(Jnk1,Atf2)[32P-ATP] is increased itpo xMlk2
    *** cells: KB in BMS
    *** source: 9639566-Fig-1d
  *** Mkk7[Ab]IP IVKA(Jnk1,Atf2)[32P-ATP] is unchanged itpo xMekk1
    *** cells: COS1 in BMS
    *** source: 9639566-Fig-1a
  *** rMkk7[tAb] boundby[WB] rPosh[GST] is undetectable
    *** cells: none
    *** source: 16571722-Fig-1a
  *** xMkk7[tAb] copptby[WB] xGadd45b[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 14743220-Fig-1a
  *** xMkk7[tAb] copptby[WB] xJip1[tAb] is detectable
    *** cells: COS7 in BMS
    *** unaffected by: xJnk1 [addition]
    *** unaffected by: xAkt1 [addition]
    *** source: 12194869(D)
  *** xMkk7[tAb] copptby[WB] xPosh[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 12514131-Fig-4d
  *** xMkk7[tAb]IP IVKA(Jnk1,Jun)[32P-ATP] is increased itpo xCdc42(G12V)"CA"
    *** cells: BAF3<IL2Rb~null> in BMS
    *** source: 9535930-Fig-6b
  *** xMkk7[tAb]IP IVKA(Jnk1,Jun)[32P-ATP] is increased itpo xCdc42(G12V)"CA"
    *** cells: HELA in BMS
    *** source: 9535930-Fig-6a
  *** xMkk7[tAb]IP IVKA(Jnk1,Jun)[32P-ATP] is increased itpo xHpk1
    *** cells: COS7 in BMS
    *** source: 9891090-Fig-8
  *** xMkk7[tAb]IP IVKA(Jnk1,Jun)[32P-ATP] is increased itpo xHras(Q61L)"CA"
    *** cells: BAF3<IL2Rb~null> in BMS
    *** source: 9535930-Fig-6b
  *** xMkk7[tAb]IP IVKA(Jnk1,Jun)[32P-ATP] is increased itpo xHras(Q61L)"CA"
    *** cells: HELA in BMS
    *** source: 9535930-Fig-6a
  *** xMkk7[tAb]IP IVKA(Jnk1,Jun)[32P-ATP] is increased itpo xMap3k12
    *** cells: COS7 in BMS
    *** source: 9891090-Fig-7
  *** xMkk7[tAb]IP IVKA(Jnk1,Jun)[32P-ATP] is increased itpo xMap4k5
    *** cells: COS7 in BMS
    *** source: 9891090-Fig-8
  *** xMkk7[tAb]IP IVKA(Jnk1,Jun)[32P-ATP] is increased itpo xMekk1
    *** cells: COS7 in BMS
    *** source: 9891090-Fig-4b,4c,7
  *** xMkk7[tAb]IP IVKA(Jnk1,Jun)[32P-ATP] is increased itpo xMlk3
    *** cells: COS7 in BMS
    *** source: 9891090-Fig-7
  *** xMkk7[tAb]IP IVKA(Jnk1,Jun)[32P-ATP] is increased itpo xRac1(G12V)"CA"
    *** cells: BAF3<IL2Rb~null> in BMS
    *** source: 9535930-Fig-6b
  *** xMkk7[tAb]IP IVKA(Jnk1,Jun)[32P-ATP] is increased itpo xRac1(G12V)"CA"
    *** cells: HELA in BMS
    *** source: 9535930-Fig-6a
  *** xMkk7[tAb]IP IVKA(Jnk1,Jun)[32P-ATP] is unchanged itpo xMekk4
    *** cells: COS7 in BMS
    *** source: 9891090-Fig-7
*** Mkk36s--
  *** Mkk36s[phosAb] phos(sitenr)[phosAb] is increased itpo xArhGef7
    *** cells: NIH3T3 in BMS
    *** source: 11309380-Fig-4a
  *** Mkk36s[phosAb] phos(sitenr)[phosAb] is increased itpo xGadd45b
    *** cells: mSpTh1 in BMS
    *** source: 12213961-Fig-1c
  *** Mkk36s[phosAb] phos(sitenr)[phosAb] is increased itpo xGadd45g
    *** cells: mSpTh1 in BMS
    *** source: 12213961-Fig-1c
  *** Mkk36s[phosAb] phos(SVAKT)[phosAb] is increased itpo xRin1(Q78L)
    *** cells: PC6 in BMLS
    *** enhanced by: xBraf [addition]
    *** source: 16157584-Fig-6h
  *** Mkk36s[phosAb] phos(SVAKT)[phosAb] is increased itpo xRin1(Q78L)
    *** cells: PC6 in BMLS
    *** source: 16157584-Fig-1d
  *** Mkk36s[phosAb] phos(SVAKT)[phosAb] is increased itpo xRin1(Q78L)
    *** cells: PC6<xBraf> in BMLS
    *** unaffected by: PD98059 [pretreatment]
    *** source: 16157584-Fig-6h
*** Mlk2--
  *** xMlk2[tAb] copptby[WB] xHpca[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 9427749-Fig-7d
  *** xMlk2[tAb] copptby[WB] xKif3a[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 9427749-Fig-7b
  *** xMlk2[tAb] copptby[WB] xPosh[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 12514131-Fig-3b
  *** xMlk2[tAb] copptby[WB] xYwhae[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 9427749-Fig-7c
  *** xMlk3(K144R)[tAb] copptby[WB] xGeft[GST] is detectable
    *** cells: HEK293T in BMS
    *** source: 18851832-Fig-7b
  *** xMlk3(K144R)[tAb]IP phos[32P-ATP] is increased by xHpk1[tAb]IP
    *** cells: none
    *** IPfrom: HELA in BMS
    *** comment: xMlk3(K144R) and xHpk1[tAb] were ppt from the same cells
    *** inhibited by: xMlk3(S281A)[tAb]IP [substitution]
    *** source: 11053428-Fig-7
  *** xMlk3(K144R/T277D/S281D)[tAb] copptby[WB] xGeft[GST] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: Anisomycin [addition]
    *** source: 18851832-Fig-7c
  *** xMlk3(mnr)"KD"[Ab]IP phos[32P-ATP] is increased by rJnk1(mnr)"CA"
    *** cells: none
    *** IPfrom: HEK293 in BMS
    *** source: 16687404(D)
  *** rMlk3[Ab] boundby[WB] rMerlinb[GST] is detectable
    *** cells: none
    *** inhibited by: rMerlinb(1-332) [substitution]
    *** enhanced by: rMerlinb(308-590) [substitution]
    *** enhanced by: rMerlinb(340-590) [substitution]
    *** source: 20890305-Fig-2b
  *** Mlk3[Ab] copptby[WB] CyclinEs[Ab] is undetectable
    *** cells: TOV21G in BMS
    *** source: 20890305-Fig-2a
  *** Mlk3[Ab] copptby[WB] Merlinb[Ab] is detectable
    *** cells: TOV21G in BMS
    *** source: 20890305-Fig-2a
  *** xMlk3[Ab] copptby[WB] xCdc42(G12V)"CA"[GST] is detectable
    *** cells: HEK293 in BMS
    *** partially inhibited by: xMlk3(L410P) [substitution]
    *** source: 10862766(D)
  *** xMlk3[Ab] copptby[WB] xCdc42(G12V)"CA"[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 16253996(D)
  *** xMlk3[Ab] copptby[WB] xCdc42(G12V)"CA"[tAb] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: xMlk3(K144A)"KD" [substitution]
    *** inhibited by: xMlk3(F498A) [substitution]
    *** inhibited by: xMlk3(H500A) [substitution]
    *** inhibited by: xMlk3(I492A/S493A) [substitution]
    *** source: 10799501(D)
  *** xMlk3[Ab] copptby[WB] xCdc42(Q61L)"CA"[GST] is detectable
    *** cells: COS7 in BMS
    *** source: 8910292(D)
  *** Mlk3[Ab] copptby[WB] xCdc42[tAb] is decreased itpo xMerlin
    *** cells: RT4<xCdc42> in BMS
    *** source: 20890305-Fig-4c
  *** xMlk3[Ab] copptby[WB] xCdc42[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 10799501(D)
  *** Mlk3[Ab] copptby[WB] xGeft[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 18851832-Fig-4d
  *** xMlk3[Ab] copptby[WB] xHras(G12V)"CA"[GST] is undetectable
    *** cells: COS7 in BMS
    *** source: 8910292(D)
  *** xMlk3[Ab] copptby[WB] xRac1(Q61L)"CA"[GST] is detectable
    *** cells: COS7 in BMS
    *** source: 8910292(D)
  *** xMlk3[Ab] copptby[WB] xRac1(Q61L)"CA"[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 8910292(D)
  *** xMlk3[Ab] copptby[WB] xRhoa(Q61L)"CA"[GST] is undetectable
    *** cells: COS7 in BMS
    *** source: 8910292(D)
  *** xMlk3[Ab] infraction(membrane)[WB] is increased itpo xCdc42(G12V)"CA"
    *** cells: HEK293 in BMS
    *** source: 16253996(D)
  *** xMlk3[Ab] phos[WBMS] is increased itpo (xMkk7 + xJnk1)
    *** cells: HEK293 in BMS
    *** source: 16687404(D)
  *** xMlk3[Ab] phos[WBMS] is increased itpo (xMkk7 + xJnk1)
    *** cells: HELA in BMS
    *** unaffected by: xMlk3(K144R)"KD" [substitution]
    *** source: 16687404(D)
  *** xMlk3[Ab] phos[WBMS] is increased itpo xCdc42(G12V)"CA"
    *** cells: HELA in BMS
    *** inhibited by: xMlk3(K144R)"KD" [substitution]
    *** source: 16687404(D)
  *** xMlk3[Ab]IP IVKA(auto)[32P-ATP] is increased itpo xCdc42(G12V)"CA"
    *** cells: HEK293 in BMS
    *** inhibited by: xMlk3(K144A) [substitution]
    *** inhibited by: xMlk3(I492A/S493A) [substitution]
    *** source: 10799501(D)
  *** xMlk3[Ab]IP IVKA(auto)[32P-ATP] is increased itpo xCdc42(G12V)"CA"
    *** cells: HEK293 in BMS
    *** unaffected by: xMlk3(L410P)"oligo-mut" [substitution]
    *** source: 10862766(D)
  *** xMlk3[Ab]IP IVKA(auto)[32P-ATP] is unchanged itpo xCdc42(G12V)"CA"
    *** cells: HEK293 in BMS
    *** source: 10799501(D)
  *** xMlk3[Ab]IP IVKA(histones)[32P-ATP] is increased itpo xCdc42(G12V)"CA"
    *** cells: HEK293 in BMS
    *** inhibited by: xMlk3(K144A) [substitution]
    *** inhibited by: xMlk3(I492A/S493A) [substitution]
    *** source: 10799501(D)
  *** xMlk3[Ab]IP IVKA(histones)[32P-ATP] is increased itpo xCdc42(G12V)"CA"
    *** cells: HEK293 in BMS
    *** unaffected by: xMlk3(L410P)"oligo-mut" [substitution]
    *** source: 10862766(D)
  *** xMlk3[Ab]IP IVKA(Mkk4)[32P-ATP] is increased itpo xCdc42(G12V)"CA"
    *** cells: HEK293 in BMS
    *** bkg inhibited by: xMlk3(L410P)"oligo-mut" [substitution]
    *** source: 10862766(D)
  *** xMlk3[Ab]IP IVKA(Mkk4)[32P-ATP] is increased itpo xCdc42(G12V)"CA"
    *** cells: HEK293 in BMS "membrane fraction"
    *** source: 16253996(D)
  *** xMlk3[Ab]IP IVKA(Mkk7)[32P-ATP] is increased itpo xCdc42(G12V)"CA"
    *** cells: HEK293 in BMS
    *** source: 16253996(D)
  *** Mlk3[phosAb] phos(T277/S281)[phosAb] is decreased itpo xMerlinb
    *** cells: HEI193 in BMS
    *** source: 20890305-Fig-3b
  *** Mlk3[phosAb] phos(T277/S281)[phosAb] is decreased itpo xMerlinb
    *** cells: RT4 in BMS
    *** source: 20890305-Fig-3a
  *** Mlk3[phosAb] phos(T277/S281)[phosAb] is decreased itpo xMerlinb
    *** cells: SKOV3 in BMS
    *** reversed by: xMerlinb(S518D) [substitution]
    *** enhanced by: xMerlinb(S518D) [substitution]
    *** source: 20890305-Fig-2e
  *** Mlk3[phosAb] phos(T277/S281)[phosAb] is decreased itpo xMerlinb
    *** cells: SKOV3 in BMS
    *** source: 20890305-Fig-3b
  *** Mlk3[phosAb] phos(T277/S281)[phosAb] is increased itao Merlin [RNAi]
    *** cells: T29 in BMS
    *** source: 20890305-Fig-3c
  *** Mlk3[phosAb] phos(T277/S281)[phosAb] is increased itao Traf2 [RNAi]
    *** cells: HEK293 in BMS
    *** source: 19586614-Fig-4
  *** xMlk3[phosAb] phos(T277/S281)[phosAb] is increased itpo xCdc42(G12V)"CA"
    *** cells: HEK293 in BMS
    *** inhibited by: xMlk3(K144R) [substitution]
    *** inhibited by: xMlk3(I492A/S493A) [substitution]
    *** source: 16253996(D)
  *** xMlk3[phosAb] phos(T277/S281)[phosAb] is increased itpo xCdc42(G12V)"CA"
    *** cells: HELA in BMS
    *** inhibited by: xMlk3(K144R)"KD" [substitution]
    *** source: 16687404(D)
  *** rMlk3[tAb] boundby[WB] rPosh[GST] is detectable
    *** cells: none
    *** source: 16571722-Fig-1a,1d
  *** xMlk3[tAb] copptby[WB] xBraf[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 16537381-Fig-2a
  *** xMlk3[tAb] copptby[WB] xCdc42[tAb] is decreased itpo xMerlin
    *** cells: HEK293<xCdc42><xMlk3> in BMS
    *** source: 20890305-Fig-4d
  *** xMlk3[tAb] copptby[WB] xCdc42[tAb] is decreased itpo xMerlin
    *** cells: HEK293<xCdc42><xMlk3> in BMS
    *** source: 20890305-Fig-4e
  *** xMlk3[tAb] copptby[WB] xCdc42[tAb] is detectable
    *** cells: HEK293<xCdc42><xMlk3> in BMS
    *** unaffected by: xCdc42(G12V) [substitution]
    *** inhibited by: xCdc42(T17N) [substitution]
    *** source: 20890305-Fig-4e
  *** xMlk3[tAb] copptby[WB] xGeft[GST] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xMlk3(475-847) [substitution]
    *** unaffected by: xMlk3(1-476) [substitution]
    *** unaffected by: xMlk3(1-376) [substitution]
    *** unaffected by: xMlk3(110-376) [substitution]
    *** source: 18851832-Fig-5a
  *** xMlk3[tAb] copptby[WB] xJip1[tAb] is detectable
    *** cells: COS7<xJnk1> in BMS
    *** reqs: xJnk1 [omission]
    *** inhibited by: xAkt1 [addition]
    *** source: 12194869(D)
  *** xMlk3[tAb] copptby[WB] xMap4k2[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 11784851(D)
  *** xMlk3[tAb] copptby[WB] xTraf2[tAb] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xTraf2(mnr)"del-Traf-domain" [substitution]
    *** unaffected by: xTraf2(mnr)"del-Ring-domain" [substitution]
    *** source: 19586614-Fig-2c
  *** xMlk3[tAb] copptby[WB] xTraf2[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 19586614-Fig-2a
  *** xMlk3[tAb] copptby[WB] xTraf6[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 19586614-Fig-2a
  *** xMlk3[tAb] oligomerization[NativeWB] is increased itpo xCdc42(G12V)"CA"
    *** cells: HEK293 in BMS
    *** inhibited by: xCdc42(T17N) [substitution]
    *** unaffected by: xMlk3(1-591)"Cterm-mutant" [substitution]
    *** source: 9829970-Fig-8
  *** xMlk3[tAb] snaggedby[WB] rCdc42(Q61L)"CA"[GST] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-2
  *** xMlk3[tAb] snaggedby[WB] rRac1(Q61L)"CA"[GST] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-2
  *** xMlk3[tAb] snaggedby[WB] rRhoa(Q63L)"CA"[GST] is undetectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-2
  *** xMlk3[tAb] snaggedby[WB] rRhog(Q61L)"CA"[GST] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-2
  *** xMlk3[tAb] snaggedby[WB] rRhog[GST] is undetectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-2
  *** xMlk3[tAb]IP IVKA(auto)(T277/S281)[phosAb] is detectable
    *** cells: HEK293<xMlk3> in BMS
    *** comment: inhibited by addition of rMerlinb(340-590) to IVKA reaction
    *** source: 20890305-Fig-2c
  *** xMlk3[tAb]IP IVKA(auto)[32P-ATP] is increased itpo xMap4k2
    *** cells: HEK293 in BMS
    *** source: 11784851(D)
  *** xMlk3[tAb]IP IVKA(auto)[32P-ATP] is increased itpo xTraf2
    *** cells: HEK293 in BMS
    *** source: 11784851(D)
  *** xMlk3[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xCdc42(Q61L)"CA"
    *** cells: COS7 in BMS
    *** source: 8910292(D)
  *** xMlk3[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xRac1(Q61L)"CA"
    *** cells: COS7 in BMS
    *** source: 8910292(D)
  *** xMlk3[tAb]IP IVKA(Mkk4)[32P-ATP] is increased itpo xMap4k2
    *** cells: HEK293 in BMS
    *** source: 11784851(D)
  *** xMlk3[tAb]IP IVKA(Mkk4)[32P-ATP] is unchanged itpo xTraf2
    *** cells: HEK293 in BMS
    *** source: 11784851(D)
  *** xMllt4[tAb] copptby[WB] xHras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xHras(G12V/D38A) [substitution]
    *** inhibited by: xHras(G12V/T35S) [substitution]
    *** inhibited by: xHras(G12V/E37G) [substitution]
    *** inhibited by: xHras(G12V/Y40C) [substitution]
    *** inhibited by: xHras(G12V/D38E) [substitution]
    *** source: 15143186-Fig-6
  *** xMllt4[tAb] copptby[WB] xHras(Q61L)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 10446149-Fig-8
  *** xMllt4[tAb] copptby[WB] xKras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xMllt4[tAb] copptby[WB] xMras(Q71L)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 10446149-Fig-8
  *** xMllt4[tAb] copptby[WB] xMras(Q71L)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xMllt4[tAb] copptby[WB] xNras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xMllt4[tAb] copptby[WB] xRap1a(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xMllt4[tAb] copptby[WB] xRap2a(G12V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xMllt4[tAb] copptby[WB] xRras(G38V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xMllt4[tAb] copptby[WB] xRras2(G23V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** Mlst8[Ab] copptby[WB] Protor1[Ab] is detectable
    *** cells: HEK293 in BMS
    *** comment: coppt works best with no detergent lysis
    *** comment: Tween = Chaps >> N-octyl-glucoside = Triton
    *** source: 17461779-Fig-3b
  *** Mlst8[Ab] copptby[WB] Protor1[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 17461779-Fig-3a
  *** Mlst8[Ab] copptby[WB] Protor1[Ab] is detectable
    *** cells: HELA in BMS
    *** source: 17461779-Fig-4c
  *** Mlst8[Ab] copptby[WB] Rictor[Ab] is detectable
    *** cells: HEK293T in BMS
    *** comment: Coppt works in Chaps-LB but not TritonX-LB
    *** source: 15268862-Fig-2b
  *** Mlst8[Ab] copptby[WB] xProtor1[tAb] is detectable
    *** cells: HEK293<xProtor1> in BMS
    *** unaffected by: xProtor1b [substitution]
    *** inhibited by: xProtor1g [substitution]
    *** source: 17461779-Fig-2d
  *** Mlst8[Ab] copptby[WB] xProtor2[tAb] is detectable
    *** cells: HEK293<xProtor1> in BMS
    *** source: 17461779-Fig-2d
  *** Mmp1-gene promo-reporter[CAT] is increased itpo (xJun + xFos)
    *** cells: COS1 in BMS
    *** enhanced by: xPml [addition]
    *** source: 9671405-Fig-1b
  *** Mmp1-gene promo-reporter[CAT] is increased itpo xFos
    *** cells: COS1 in BMS
    *** unaffected by: xPml [addition]
    *** unaffected by: xJun [addition]
    *** enhanced by: xPml + xJun [addition]
    *** source: 9671405-Fig-1c
  *** Mmp1-gene promo-reporter[CAT] is increased itpo xJun
    *** cells: COS1 in BMS
    *** enhanced by: xFos [addition]
    *** unaffected by: xPml [addition]
    *** source: 9671405-Fig-1b
  *** Mmp1-gene promo-reporter[CAT] is increased itpo xJun
    *** cells: COS1 in BMS
    *** unaffected by: xPml [addition]
    *** unaffected by: xFos [addition]
    *** enhanced by: xPml + xFos [addition]
    *** source: 9671405-Fig-1c
  *** Mmp1-gene promo-reporter[CAT] is increased itpo xPml
    *** cells: COS1 in BMS
    *** source: 9671405-Fig-1c
  *** Mmp1-gene promo-reporter[CAT] is unchanged itpo xPml
    *** cells: COS1 in BMS
    *** source: 9671405-Fig-1b
  *** Mmp1-gene promo-reporter[Luc] is increased itpo (xJun + xFos)
    *** cells: MV1LU in BMS
    *** enhanced by: xSmad3 [addition]
    *** source: 9732876-Fig-1d
  *** Mmp1-gene promo-reporter[Luc] is increased itpo xJun
    *** cells: F9 in BMS
    *** enhanced by: xSmad3 [addition]
    *** enhanced by: xFos [addition]
    *** source: 9732876-Fig-1d
  *** Mmp1-gene promo-reporter[Luc] is unchanged itpo xElk1(1-428)
    *** cells: hChondrocytes in BMLS
    *** bkg inhibited by: xElk1((1-428)/S383A) [substitution]
    *** source: 17724016-Fig-2c
*** Mmp1-gene--
  *** Mmp2-gene mRNA[RTPCR] is unchanged itao Smad2 [KO]
    *** cells: mEFs in BMS
    *** source: 20595680-Fig-6c
  *** Mmp2-gene mRNA[RTPCR] is unchanged itao Smad2 [RNAi]
    *** cells: mTECs in BMS
    *** source: 20595680-Fig-6b
  *** Mmp7-gene mRNA[RTPCR] is decreased itao Tnik [RNAi]
    *** cells: DLD1 in BMS
    *** source: 20530691-Fig-5
  *** Mmp7-gene mRNA[RTPCR] is decreased itao Tnik [RNAi]
    *** cells: HCT116 in BMS
    *** source: 20530691-Fig-5
  *** Mmp13-gene promo-reporter[Luc] is increased itpo xElk1(1-428)
    *** cells: hChondrocytes in BMLS
    *** bkg inhibited by: xElk1((1-428)/S383A) [substitution]
    *** source: 17724016-Fig-2c
  *** rMnk1 IVKA(peptide)[32P-ATP] is unchanged by rJnk2{act}
    *** cells: none
    *** unaffected by: rMnk1(K78R)"KD" [substitution]
    *** unaffected by: SB202190 [addition]
    *** source: 9155018-Fig-8b
  *** rMnk1 phos[32P-ATP] is unchanged by rJnk2{act}
    *** cells: none
    *** unaffected by: SB202190 [addition]
    *** source: 9155018-Fig-8a
*** Mnk1--
  *** rMnk1[32P] phos[32P-ATP] is unchanged by rJnk1(mnr)"CA"
    *** cells: none
    *** source: 11154262-Fig-1a
  *** Mnk1[Ab] copptby[WB] Eif4ebp1[Ab] is undetectable
    *** cells: HEK293 in BMS
    *** source: 9878069-Fig-1
  *** xMnk1[GST]IP phos[WBMS] is increased itpo xMek1(S218E/S222E)"CA"
    *** cells: NIH3T3<xMnk1> in BMLS
    *** inhibited by: xMek1 [substitution]
    *** inhibited by: xMek1(S222A)"DN" [substitution]
    *** inhibited by: xMek1(K97A)"KD" [substitution]
    *** source: 9155017-Fig-6b
*** Mnk2--
  *** rMnk2[32P] phos[32P-ATP] is unchanged by rJnk1(mnr)"CA"
    *** cells: none
    *** source: 11154262-Fig-1a
  *** Mnk2[Ab]IP IVKA(Eif4e)[32P-ATP] is detectable
    *** cells: HEK293 in BMLS
    *** unaffected by: PMA (30 min) [stim]
    *** source: 11154262-Fig-5c
  *** xMnk2[tAb]IP IVKA(Eif4e)[32P-ATP] is detectable
    *** cells: HEK293 in BMLS
    *** unaffected by: PMA (0,5,15,30 min) [stim]
    *** source: 11154262-Fig-5a
  *** xMnk2[tAb]IP IVKA(Eif4e)[32P-ATP] is detectable
    *** cells: HEK293 in BMLS
    *** unaffected by: PMA (30 min) [stim]
    *** source: 11154262-Fig-6a
  *** xMnk2[tAb]IP IVKA(Eif4e)[32P-ATP] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xMnk2(T197A) [substitution]
    *** inhibited by: xMnk2(T202A) [substitution]
    *** inhibited by: xMnk2(T332A) [substitution]
    *** unaffected by: xMnk2(T332D) [substitution]
    *** unaffected by: xMnk2(T403A) [substitution]
    *** unaffected by: xMnk2(T403D) [substitution]
    *** source: 11154262-Fig-4a
  *** xMnk2b[XFP] infraction(cyto-nuc)[WB] is detectable
    *** cells: HEK293<xMnk2b> in BMS
    *** source: 12897141-Fig-5b
  *** xMnk2b[XFP] locatedin(nucleus)[IHC] is detectable
    *** cells: HEK293<xMnk2b> in BMS
    *** inhibited by: xMnk2b(del(60-70))"delBR" [substitution]
    *** unaffected by: xMnk2(K60A/K61A/R62A) [substitution]
    *** inhibited by: xMnk2(K64A/K66A/K67A) [substitution]
    *** source: 12897141-Fig-5c
  *** xMnk2b[XFP] locatedin(nucleus)[IHC] is detectable
    *** cells: HEK293<xMnk2b> in BMS
    *** source: 12897141-Fig-5a
  *** rMras GDP-dissociation[3H-GDP] is unchanged by rPlce1
    *** cells: none
    *** source: 11395506-Fig-3
  *** rMras GDP-dissociation[Mant-GDP] is unchanged by rRapGef1
    *** cells: none
    *** source: 10777492-Fig-2
  *** rMras GDP-dissociation[Mant-GDP] is unchanged by rRapGef3
    *** cells: none
    *** source: 10777492-Fig-2
  *** rMras GDP-dissociation[Mant-GDP] is unchanged by rRasGef1a
    *** cells: none
    *** source: 19645719-Fig-1c
  *** rMras GDP-dissociation[Mant-GDP] is unchanged by rRasGef1b
    *** cells: none
    *** source: 19645719-Fig-1c
  *** rMras GDP-dissociation[Mant-GDP] is unchanged by rRasGrp2
    *** cells: none
    *** source: 10777492-Fig-2
  *** rMras GTP-hydrolysis[32P-GTP] is unchanged by rRasa3
    *** cells: none
    *** source: 10777492-Fig-3
*** Mras--
  *** xMras[GST]IP GTP-association[TLC] is increased itpo xSos1
    *** cells: HEK293T in BMS
    *** source: 10777492-Fig-1a
  *** xMras[GST]IP GTP-association[TLC] is unchanged itpo xRalGps1
    *** cells: HEK293T in BMS
    *** source: 10777492-Fig-1a
  *** xMras[GST]IP GTP-association[TLC] is unchanged itpo xRapGef1
    *** cells: HEK293T in BMS
    *** unaffected by: xRapGef1(mnr)"CA" [substitution]
    *** source: 10777492-Fig-1a,1b
  *** xMras[GST]IP GTP-association[TLC] is unchanged itpo xRapGef2
    *** cells: HEK293T in BMS
    *** source: 10777492-Fig-1a
  *** xMras[GST]IP GTP-association[TLC] is unchanged itpo xRapGef3
    *** cells: HEK293T in BMS
    *** unaffected by: cAMP [addition]
    *** source: 10777492-Fig-1a
  *** xMras[GST]IP GTP-association[TLC] is unchanged itpo xRapGef5
    *** cells: HEK293T in BMS
    *** source: 10777492-Fig-1a
  *** xMras[GST]IP GTP-association[TLC] is unchanged itpo xRasGrp2
    *** cells: HEK293T in BMS
    *** source: 10777492-Fig-1a
  *** xMras[tAb]IP GTP-association[TLC] is increased itpo xSos1(mnr)"CA"
    *** cells: HEK293T in BMS
    *** source: 10446149-Fig-8
  *** rMras{NucFree}[GST] boundby[WB] rRgl3(1-557)"delRBD"[tAb] is undetectable
    *** cells: none
    *** source: 10869344-Fig-6a
*** Mre11--
  *** rMre11[Ab] boundby[WB] sMdc1(325-340){phos(S329/T331)}[biotin] is detectable
    *** cells: none
    *** comment: reaction also contains rRad50 and rNbs1
    *** source: 18583988-Fig-3a
  *** Mre11[Ab] copptby[WB] Atrip[Ab] is undetectable
    *** cells: HELA in BMS
    *** source: 16431910-Fig-S1
  *** Mre11[Ab] copptby[WB] Mrc1[Ab] is detectable
    *** cells: HELA in BMS "nuclear-extracts"
    *** source: 12607003-Fig-1c
  *** Mre11[Ab] copptby[WB] xAtm[tAb] is detectable
    *** cells: NotReported<xAtm><xNbs1> in BMS
    *** inhibited by: xNbs1(1-734)"delC" [substitution]
    *** inhibited by: xNbs1(N684A/F685A/K686A/K687A)"dMIR" [substitution]
    *** source: 15758953-Fig-1e
  *** Mre11[Ab] copptby[WB] xMdc1[tAb] is detectable
    *** cells: HEK293T<xMdc1> in BMS
    *** inhibited by: xMdc1(del(196-506)) [substitution] 
    *** source: 18583988-Fig-4b
  *** xMre11[Ab] infraction(chromatin)[WB] is increased itpo xNbs1
    *** cells: NBS1LBI<Nbs1~fmut><xMre11> in BMS
    *** source: 16478990-Fig-5a
  *** Mre11[Ab] infraction(nuclear)[WB] is detectable
    *** cells: GM637 in BMS
    *** source: 16478990-Fig-2a
  *** Mre11[Ab] infraction(nuclear)[WB] is detectable
    *** cells: NBS1LBI<Nbs1~fmut><xNbs1> in BMS
    *** partially reqs: xNbs1 [omission]
    *** source: 16478990-Fig-2a
  *** Mre11[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: NBS1LBI<Nbs1~fmut><xNbs1> in BMS "treated with IR for 1 hr"
    *** reqs: xNbs1 [omission]
    *** unaffected by: xNbs1(1-734)"delC" [substitution]
    *** source: 15758953-Fig-2f
  *** Mre11[Ab] locatedin(nucleus)[IHC] is increased itpo xNbs1
    *** cells: NBS1LBI<Nbs1~fmut> in BMS
    *** inhibited by: xNbs1(1-652) [substitution]
    *** unaffected by: xNbs1(401-754) [substitution]
    *** unaffected by: xNbs1(S278A/S343A) [substitution]
    *** source: 15234984-Fig-1b
  *** xMre11[Ab] locatedin(subnuclear-bodies)[IHC] is detectable
    *** cells: D6809<Mre11~fmut><xMre11> in BMS "treated with IR for 6 hr"
    *** unaffected by: xMre11(NLS) [substitution]
    *** source: 16478990-Fig-4d
  *** Mre11[Ab] prot-exp[WB] is detectable
    *** cells: HCT116 in BMS
    *** reqs: Rad50 [RNAi]
    *** source: 16087684-Fig-1a
  *** Mre11[Ab] prot-exp[WB] is detectable
    *** cells: HEK293T in BMS
    *** partially reqs: Rad50 [RNAi]
    *** source: 16087684-Fig-1a
  *** Mre11[Ab] snaggedby[WB] dsDNA[biotin] is detectable
    *** cells: NBS1LBI<Nbs1~fmut><xNbs1> in BMS
    *** does not req: xNbs1 [omission]
    *** unaffected by: xNbs1(1-734)"delC" [substitution]
    *** source: 15758953-Fig-2a
  *** Mre11[Ab] snaggedby[WB] rAtrip(765-791)[biotin] is undetectable
    *** cells: HELA in BMS "nuclear-extract"
    *** source: 15758953-Fig-S4a
  *** Mre11[Ab] snaggedby[WB] rKi67(1-137)[GST] is undetectable
    *** cells: HELA in BMS "nuclear-extracts"
    *** source: 12607003-Fig-1e
  *** Mre11[Ab] snaggedby[WB] rKu80(718-732)[biotin] is undetectable
    *** cells: HELA in BMS "nuclear-extract"
    *** source: 15758953-Fig-S4a
  *** Mre11[Ab] snaggedby[WB] rMdc1(2-220)"FHA"[GST] is detectable
    *** cells: HELA in BMS "nuclear-extracts"
    *** partially inhibited by: rMdc1(2-220/R58A) [substitution]
    *** partially inhibited by: rMdc1(1883-2089)"BRCT" [substitution]
    *** inhibited by: rMdc1(1459-1500)"RM" [substitution]
    *** source: 12607003-Fig-1e
  *** Mre11[Ab] snaggedby[WB] rMdc1(296-340){phos}[GST] is detectable
    *** cells: HELA in BMS "nuclear-extract"
    *** comment: rMdc1(296-340) was phosed by rCsnk2
    *** inhibited by: rMdc1(296-340/T301A/T331A) [substitution]
    *** source: 18583988-Fig-2d
  *** Mre11[Ab] snaggedby[WB] sH2ax(123-143){phos(S140)}[GST] is detectable
    *** cells: HELA in BMS "nuclear-extracts"
    *** inhibited by: sH2ax(123-143) [substitution]
    *** source: 16377563-Fig-1b
  *** Mre11[Ab] snaggedby[WB] sH2ax(124-143){phos(S140)}[biotin] is detectable
    *** cells: HELA in BMS
    *** inhibited by: sH2ax(124-143) [substitution]
    *** source: 15201865-Fig-5b
  *** Mre11[Ab] snaggedby[WB] sH2ax(124-143){phos(S140)}[biotin] is detectable
    *** cells: HELA in BMS
    *** reqs: Mdc1 [RNAi]
    *** source: 15201865-Fig-5b
  *** Mre11[Ab] snaggedby[WB] sH2ax(134-143){phos(S140)}[biotin] is detectable
    *** cells: HELA in BMS "nuclear-extract"
    *** inhibited by: sH2ax(134-143) [substitution]
    *** source: 18583988-Fig-1c
  *** Mre11[Ab] snaggedby[WB] sMdc1(325-340){phos(S329/T331)}[biotin] is detectable
    *** cells: HELA in BMS "nuclear-extract"
    *** inhibited by: sMdc1(325-340) [substitution]
    *** source: 18583988-Fig-1c
*** Msk1--
  *** xMsk1[Ab] copptby[WB] Ripk1[Ab] is undetectable
    *** cells: HEK293 in BMS
    *** source: 16291755-Fig-2b
  *** xMsk1[GST]IP IVKA(auto)[32P-ATP] is unchanged by rJnk1{act}
    *** cells: HEK293<xMsk1> in BMLS
    *** source: 9687510-Fig-3d
  *** xMsk1[GST]IP IVKA(auto)[32P-ATP] is unchanged by rP38d{act}
    *** cells: HEK293<xMsk1> in BMLS
    *** source: 9687510-Fig-3d
  *** xMsk1[GST]IP IVKA(auto)[32P-ATP] is unchanged by rP38g{act}
    *** cells: HEK293<xMsk1> in BMLS
    *** source: 9687510-Fig-3d
  *** xMsk1[GST]IP IVKA(Crosstide)[32P-ATP] is decreased by Ro318220
    *** cells: HEK293<xMsk1> in BMLS
    *** source: 9687510-Fig-9a
  *** xMsk1[GST]IP IVKA(Crosstide)[32P-ATP] is unchanged by rJnk1{act}
    *** cells: HEK293<xMsk1> in BMLS
    *** source: 9687510-Fig-3b
  *** xMsk1[GST]IP IVKA(Crosstide)[32P-ATP] is unchanged by rP38d{act}
    *** cells: HEK293<xMsk1> in BMLS
    *** source: 9687510-Fig-3b
  *** xMsk1[GST]IP IVKA(Crosstide)[32P-ATP] is unchanged by rP38g{act}
    *** cells: HEK293<xMsk1> in BMLS
    *** source: 9687510-Fig-3b
  *** xMsk1[tAb]IP IVKA(Crebtide)[32P-ATP] is unchanged itpo xRsk1
    *** cells: HEK293<xMsk1> in BMS
    *** source: 12234923-Fig-7
*** MsR1--
  *** MsR1-gene mRNA[RTPCR] is detectable
    *** cells: BEAS2B in BMS
    *** source: 17709607-Fig-3a
  *** MsR1-gene mRNA[RTPCR] is detectable
    *** cells: hBECs in BMLS
    *** source: 17709607-Fig-3a
*** MsR1-gene--
  *** MsR1[Ab] prot-exp[WB] is detectable
    *** cells: BEAS2B in BMS
    *** source: 17709607-Fig-3a
  *** MsR1[Ab] prot-exp[WB] is detectable
    *** cells: hBECs in BMLS
    *** source: 17709607-Fig-3a
*** Mtor--
  *** xMtor(2148-2549)[tAb] copptby[WB] xRheb[GST] is detectable
    *** cells: HEK293<xRheb><xMtor(2148-2549)> in BMS
    *** comment: inhibited by refeed with BSS for 2 hr
    *** comment: inhibited by refeed with BSS+AAs-Leu for 2 hr
    *** comment: inhibited by refeed with BSS for 90 min
    *** comment: unaffected by refeed with BSS for 90 min + AAs for 30 min
    *** comment: unaffected by refeed with BSS+AAs for 90 min
    *** comment: unaffected by refeed with BSS+AAs for 90 min + Leu for 30 min
    *** source: 15878852-Fig-2d
  *** Mtor[Ab] colocwith[IHC] xRab7a[XFP] is increased itpo xRagB(Q99L)"GTP"
    *** cells: HEK293T in BMS "AminoAcid and Serum deprived"
    *** unaffected by: AminoAcids (10 min) [stim]
    *** source: 18497260-Fig-5b
  *** Mtor[Ab] copptby[WB] (xRagB(Q99L)"GTP"[tAb] + xRagC(Q120L)"GTP"[tAb]) is detectable
    *** cells: HEK293T<xRagB(Q99L)><xRagC(Q120L)> in BMS
    *** unaffected by: xRagC(S75L)"GDP" [substitution]
    *** inhibited by: xRagB(T54L)"GDP" [substitution]
    *** source: 18497260-Fig-1c
  *** Mtor[Ab] copptby[WB] Atm[Ab] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15268862-Fig-1c
  *** Mtor[Ab] copptby[WB] EgfR[Ab] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15268862-Fig-1c
  *** Mtor[Ab] copptby[WB] Protor1[Ab] is detectable
    *** cells: HEK293 in BMS
    *** comment: coppt works best with no detergent lysis
    *** comment: Tween = Chaps >> N-octyl-glucoside = Triton
    *** source: 17461779-Fig-3b
  *** Mtor[Ab] copptby[WB] Protor1[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 17461779-Fig-3a
  *** Mtor[Ab] copptby[WB] Protor1[Ab] is detectable
    *** cells: HELA in BMS
    *** source: 17461779-Fig-4c
  *** Mtor[Ab] copptby[WB] Rictor[Ab] is detectable
    *** cells: HEK293E in BMS
    *** comment: unaffected by washing ppt with high salt
    *** source: 19446321-Fig-1d
  *** Mtor[Ab] copptby[WB] Rictor[Ab] is detectable
    *** cells: HEK293T in BMS
    *** source: 15467718-Fig-1
  *** Mtor[Ab] copptby[WB] Rictor[Ab] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xDeptor [addition]
    *** unaffected by: xDeptor(dig)"13ST/A" [addition]
    *** source: 19446321-Fig-5a
  *** Mtor[Ab] copptby[WB] xPras40[tAb] is decreased itpo xAkt1
    *** cells: HEK293T<xPras40><xYwha?> in BMS
    *** reversed by: xPras40(T246A) [substitution]
    *** source: 17277771-Fig-4a
  *** xMtor[Ab] copptby[WB] xProtor1[Ab] is detectable
    *** cells: HEK293<xMtor><xRictor><xSin1><xProtor1><xMlst8> in BMS
    *** reqs: xRictor [omission]
    *** reqs: xSin1 [omission]
    *** source: 17461779-Fig-4a
  *** Mtor[Ab] copptby[WB] xProtor1[tAb] is detectable
    *** cells: HEK293<xProtor1> in BMS
    *** unaffected by: xProtor1b [substitution]
    *** inhibited by: xProtor1g [substitution]
    *** source: 17461779-Fig-2d
  *** Mtor[Ab] copptby[WB] xProtor2[tAb] is detectable
    *** cells: HEK293<xProtor1> in BMS
    *** source: 17461779-Fig-2d
  *** Mtor[Ab] copptby[WB] xS6k1[tAb] is undetectable
    *** cells: HEK293T<xS6k1> in BMS
    *** source: 17277771-Fig-S1c
  *** Mtor[Ab] copptby[WB] xS6k1[tAb] is undetectable
    *** cells: HEK293T<xS6k1> in BMS
    *** source: 17277771-Fig-S3b
  *** Mtor[Ab] infraction(P100)[WB] is detectable
    *** cells: HELA in BMLS
    *** source: 21464307-Fig-5c
  *** Mtor[Ab] infraction(P100)[WB] is detectable
    *** cells: HELA in BMS
    *** source: 21464307-Fig-5c
  *** Mtor[Ab] infraction(P100)[WB] is detectable
    *** cells: MDCK2 in BMS
    *** source: 21464307-Fig-5c
  *** Mtor[Ab] locatedin(vesicles)[IHC] is increased itpo xRagB(Q99L)"GTP"
    *** cells: HEK293T in BMS "AminoAcid and Serum deprived"
    *** unaffected by: AminoAcids (10 min) [stim]
    *** source: 18497260-Fig-4d
  *** Mtor[Ab] snaggedby[WB] rEif4ebp1[GST] is increased itao Pras40 [RNAi]
    *** cells: CHO<xInsR> in BMLS
    *** source: 17510057-Fig-6a
  *** Mtor[Ab]IP IVKA(Akt1)(S473)[phosAb] is detectable
    *** cells: HEK293T in BMS
    *** comment: Mtor IP contains both Rictor and Raptor
    *** source: 15718470-Fig-3a
  *** Mtor[Ab]IP IVKA(Akt1)(S473)[phosAb] is detectable
    *** cells: HEK293T in BMS
    *** reqs: Rictor [RNAi]
    *** source: 15718470-Fig-3b
  *** Mtor[Ab]IP IVKA(Akt1)(S473)[phosAb] is detectable
    *** cells: HELA in BMS
    *** comment: Mtor IP contains both Rictor and Raptor
    *** source: 15718470-Fig-3a
  *** Mtor[Ab]IP IVKA(Akt1)(S473)[phosAb] is detectable
    *** cells: HELA in BMS
    *** inhibited by: LY294002 [pretreatment]
    *** inhibited by: Wortmannin [pretreatment]
    *** inhibited by: Rapamycin [pretreatment]
    *** source: 21464307-Fig-5b
  *** Mtor[Ab]IP IVKA(Akt1)(S473)[phosAb] is detectable
    *** cells: HELA in BMS
    *** partially reqs: Rictor [RNAi]
    *** partially reqs: Sin1 [RNAi]
    *** does not req: Raptor [RNAi]
    *** comment: Mtor IP contains Rictor, Sin1, and Raptor
    *** source: 17043309-Fig-4a
  *** Mtor[Ab]IP IVKA(Akt1)(S473)[phosAb] is detectable
    *** cells: HELA<xIkke> in BMS
    *** unaffected by: xIkke(mnr)"KD" [substitution]
    *** source: 21464307-Fig-S5c
  *** Mtor[Ab]IP IVKA(Akt1)(S473)[phosAb] is increased itao Deptor [RNAi]
    *** cells: HELA in BMS
    *** source: 19446321-Fig-2d
  *** Mtor[Ab]IP IVKA(Akt1)(S473)[phosAb] is increased itao Deptor [RNAi]
    *** cells: RPMI8226 in BMS
    *** source: 19446321-Fig-S7
  *** Mtor[Ab]IP IVKA(Akt1)(T308)[phosAb] is undetectable
    *** cells: HELA in BMS
    *** source: 21464307-Fig-5b
  *** Mtor[Ab]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: HEK293 in BMS
    *** comment: cells were lysed without detergent
    *** comment: IP is less active on Mtor after wash with high salt
    *** source: 12150926-Fig-1a
  *** Mtor[Ab]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: HEK293 in BMS
    *** comment: cells were lysed without detergent
    *** comment: unaffected by Serum-deprivation and/or AA-deprivation
    *** unaffected by: Rapamycin [addition]
    *** source: 12150926-Fig-2b
  *** xMtor[Ab]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: HEK293<xMtor> in BMS
    *** comment: cells were lysed without detergent
    *** comment: enhanced by addition of 1% NP50 to the lysis buffer
    *** unaffected by: xRaptor [addition]
    *** source: 12150926-Fig-3a
  *** xMtor[Ab]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: HEK293<xMtor> in BMS
    *** enhanced by: xRaptor [addition]
    *** source: 12150926-Fig-3c
  *** xMtor[Ab]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: HEK293<xMtor> in BMS
    *** inhibited by: xMtor(N2343K)"KD" [substitution]
    *** source: 12150926-Fig-3c
  *** Mtor[Ab]IP IVKA(Eif4ebp1)(T37/T46)[phosAb] is increased itao Deptor [RNAi]
    *** cells: HELA in BMS
    *** source: 19446321-Fig-2b
  *** Mtor[Ab]IP IVKA(Eif4ebp1)[32P-ATP] is detectable
    *** cells: HEK293 in BMS
    *** comment: cells were lysed without detergent
    *** comment: IP is active on Eif4ebp1 only after wash with high salt
    *** source: 12150926-Fig-1a
  *** Mtor[Ab]IP IVKA(Eif4ebp1)[32P-ATP] is detectable
    *** cells: HEK293 in BMS
    *** comment: cells were lysed without detergent
    *** comment: unaffected by Serum-deprivation and/or AA-deprivation
    *** partially inhibited by: Rapamycin [addition]
    *** source: 12150926-Fig-2b
  *** Mtor[Ab]IP IVKA(S6k1)(T412)[phosAb] is increased itao Deptor [RNAi]
    *** cells: HELA in BMS
    *** source: 19446321-Fig-2b
  *** Mtor[Ab]IP IVKA(S6k1)(T412)[phosAb] is increased itao Deptor [RNAi]
    *** cells: RPMI8226 in BMS
    *** source: 19446321-Fig-S7
  *** xMtor[Ab]IP IVKA(S6k1)[32P-ATP] is detectable
    *** cells: HEK293<xMtor> in BMS
    *** inhibited by: xMtor(N2343K)"KD" [substitution]
    *** source: 12150926-Fig-3c
  *** Mtor[Ab]IP phos(S2448)[phosAb] is increased by pAkt1{act}
    *** cells: none
    *** IPfrom: HEK293 in BMLS
    *** source: 10567225-Fig-2b
  *** Mtor[Ab]IP phos(S2481)[phosAb] is detectable
    *** cells: JURKATT in BMS
    *** inhibited by: xMtor(D2357E)"KD" [substitution]
    *** source: 10702316-Fig-7d
  *** Mtor[Ab]IP phos[32P-ATP] is increased by pAkt1{act}
    *** cells: none
    *** IPfrom: HEK293 in BMLS
    *** source: 10567225-Fig-2a
  *** xMtor[phosAb] phos(S2448)[phosAb] is decreased itpo (xTsc1 + xTsc2)
    *** cells: HEK293 in BMS
    *** source: 12172553-Fig-7e
  *** xMtor[phosAb] phos(S2448)[phosAb] is increased itao Tsc2 [RNAi]
    *** cells: HEK293 in BMS
    *** source: 12172553-Fig-7e
  *** xMtor[phosAb] phos(S2448)[phosAb] is increased itpo xRheb
    *** cells: HEK293<xMtor> in BMS
    *** source: 12869586-Fig-4c
  *** Mtor[phosAb] phos(sitenr)[phosAb] is increased itao Tsc2 [RNAi]
    *** cells: WM35 in BMS
    *** source: 18570873-Fig-7e
  *** xMtor[tAb] copptby[WB] xEif3f[tAb] is detectable
    *** cells: HEK293T in BMLS "AminoAcid deprived"
    *** source: 16541103-Fig-1d
  *** xMtor[tAb] copptby[WB] xHras(G12V)[GST] is undetectable
    *** cells: HEK293T<xHras(G12V)><xMtor> in BMS
    *** source: 15854902-Fig-2c
  *** xMtor[tAb] copptby[WB] xLamtor2[tAb] is detectable
    *** cells: HEK293T<xLamtor2><xLamtor3><xLamtor1><xMtor><xRaptor><xRagB(Q99L)"GTP"><xRagD(S77L)"GDP"> in BMS
    *** reqs: xRagB(Q99L)"GTP" and/or xRagD(S77L)"GDP" [omission]
    *** source: 20381137-Fig-2c
  *** xMtor[tAb] copptby[WB] xRagD(S77L)"GDP"[tAb] is detectable
    *** cells: HEK293T<xRaptor><xMtor><xRagB(Q99L)><xRagD(S77L)> in BMS
    *** inhibited by: xRagB(T54L)"GDP" + xRagD(Q121L)"GTP" [substitution]
    *** source: 18497260-Fig-1d
  *** xMtor[tAb] copptby[WB] xRagD(S77L)"GDP"[tAb] is detectable
    *** cells: HEK293T<xRaptor><xMtor><xRagB(Q99L)><xRagD(S77L)> in BMS
    *** reqs: xRaptor [omission]
    *** source: 18497260-Fig-1d
  *** xMtor[tAb] copptby[WB] xRap1b(G12V)[GST] is undetectable
    *** cells: HEK293T<xRap1b(G12V)><xMtor> in BMS
    *** source: 15854902-Fig-2c
  *** xMtor[tAb] copptby[WB] xRaptor[tAb] is detectable
    *** cells: HEK293T<xMtor><xPras40><xRaptor> in BMS
    *** comment: inhibited by replacement of Tween20 by TritonX in lysis buffer
    *** source: 17510057-Fig-2c
  *** xMtor[tAb] copptby[WB] xRaptor[tAb] is detectable
    *** cells: HEK293T<xMtor><xRaptor><xPras40> in BMS
    *** source: 17510057-Fig-1c
  *** xMtor[tAb] copptby[WB] xRheb[tAb] is decreased itpo (xTsc1 + xTsc2)
    *** cells: HEK293T<xMtor><xRheb> in BMLS
    *** source: 15772076-Fig-6c
  *** xMtor[tAb] snaggedby[WB] rEif3f[GST] is detectable
    *** cells: HEK293T in BMLS "AminoAcid deprived"
    *** source: 16541103-Fig-1b
  *** xMtor[tAb] snaggedby[WB] rFkbp12[GST] is detectable
    *** cells: COS7<xMtor> in BMS
    *** comment: requires prebinding of Rapamycin to rFkbp12
    *** source: 9334222-Fig-2a
  *** xMtor[tAb] snaggedby[WB] rFkbp12[GST] is detectable
    *** cells: HEK293<xMtor> in BMS
    *** comment: requires prebinding of Rapamycin to rFkbp12
    *** unaffected by: xMtor(S2035A) [substitution]
    *** inhibited by: xMtor(S2035T) [substitution]
    *** inhibited by: xMtor(S2035R) [substitution]
    *** unaffected by: xMtor(N2343K) [substitution]
    *** source: 9334222-Fig-2b
  *** xMtor[tAb]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: CHO<xInsR> in BMLS
    *** inhibited by: xMtor(N2343K) [substitution]
    *** partially inhibited by: xMtor(S2035R) [substitution]
    *** source: 9334222-Fig-1a
  *** xMtor[tAb]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: HEK293 in BMS
    *** source: 9405468-Fig-1a
  *** xMtor[tAb]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: JURKATT in BMS
    *** inhibited by: xMtor(D2357E)"KD" [substitution]
    *** source: 10702316-Fig-5
  *** xMtor[tAb]IP IVKA(Eif4ebp1)[32P-ATP] is detectable
    *** cells: FDCP1 in BMLS "IL3 deprived"
    *** inhibited by: xMtor(D2357E)"KD" [substitution]
    *** source: 10910062-Fig-1a
  *** xMtor[tAb]IP IVKA(Pras40)[32P-ATP] is detectable
    *** cells: HEK293E<xMtor><xRaptor> in BMS
    *** inhibited by: xMtor(S2338A)"KD" [substitution]
    *** enhanced by: xMtor(del(2433-2451))"CA" [substitution]
    *** source: 18372248-Fig-1b
  *** xMtor[tAb]IP IVKA(S6k1)(T412)[phosAb] is increased itpo xRap1b(G12V)
    *** cells: HEK293T<xMtor> in BMS
    *** source: 15854902-Fig-S5
  *** xMtor[tAb]IP IVKA(S6k1)(T412)[phosAb] is unchanged itpo xHras(G12V)
    *** cells: HEK293T<xMtor> in BMS
    *** source: 15854902-Fig-S5
  *** xMtor[tAb]IP IVKA(S6k1)[32P-ATP] is decreased itpo (xTsc1 + xTsc2)
    *** cells: HEK293 in BMS
    *** source: 12172553-Fig-7d
  *** xMtor[tAb]IP IVKA(S6k1)[32P-ATP] is increased itpo xRap1b(G12V)
    *** cells: HEK293T<xMtor> in BMS
    *** source: 15854902-Fig-S5
  *** xMtor[tAb]IP IVKA(S6k1)[32P-ATP] is unchanged itpo xHras(G12V)
    *** cells: HEK293T<xMtor> in BMS
    *** source: 15854902-Fig-S5
  *** xMtor[tAb]IP phos(S2481)[phosAb] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xMtor(D2357E)"KD" [substitution]
    *** source: 10702316-Fig-6
  *** xMtor[tAb]IP phos(S2481)[phosAb] is detectable
    *** cells: JURKATT in BMS
    *** inhibited by: xMtor(D2357E)"KD" [substitution]
    *** source: 10702316-Fig-6
  *** xMtor[tAb]IP phos[32Pi] is detectable
    *** cells: JURKATT in BMS
    *** comment: phos-site was determined to be S2481 by MS
    *** source: 10702316-Fig-1,2
*** Muc1--
  *** Muc1[Ab] copptby[WB] Apc[Ab] is detectable
    *** cells: ZR751 in BMS
    *** source: 15020226-Fig-1a
  *** Muc1[Ab] copptby[WB] Apc[Ab] is undetectable
    *** cells: MDAMB468 in BMS
    *** source: 15020226-Fig-1a
  *** Muc1[Ab] copptby[WB] Apc[Ab] is undetectable
    *** cells: SKBR3 in BMS
    *** source: 15020226-Fig-1a
  *** Muc1[Ab] copptby[WB] Apc[Ab] is undetectable
    *** cells: T47D in BMS
    *** source: 15020226-Fig-1a
  *** Muc1[Ab] copptby[WB] EgfR[Ab] is detectable
    *** cells: ZR751 in BMS
    *** source: 11483589-Fig-1a
  *** Muc1[Ab] copptby[WB] Ikk2[Ab] is detectable
    *** cells: MCF7 in BMS
    *** source: 18037881-Fig-2a
  *** Muc1[Ab] copptby[WB] Ikk2[Ab] is detectable
    *** cells: ZR751 in BMS
    *** source: 18037881-Fig-2a
  *** Muc1[Ab] copptby[WB] Nemo[Ab] is detectable
    *** cells: MCF7 in BMS
    *** source: 18037881-Fig-2a
  *** Muc1[Ab] copptby[WB] Nemo[Ab] is detectable
    *** cells: ZR751 in BMS
    *** source: 18037881-Fig-2a
  *** xMuc1[Ab] copptby[WB] xEgfR[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 11483589-Fig-1a
  *** xMuc1[Ab]IP Yphos[pYAb] is detectable
    *** cells: HCT116 in BMS
    *** partially inhibited by: xMuc1(Y46F) [substitution]
    *** source: 11483589-Fig-3d
  *** xMuc20[tAb] oligomerization[2TagPpt] is detectable
    *** cells: HEK293<xMuc20> in BMS
    *** source: 15314156-Fig-5a
*** Myc--
  *** Myc-gene mRNA[Northern] is increased itpo xPin1
    *** cells: MCF7 in BMS
    *** source: 11533658-Fig-1b
  *** Myc-gene mRNA[RPA] is decreased itpo xSmad3
    *** cells: BALBMK in BMS
    *** enhanced by: xSmad4 [addition]
    *** source: 14993291-Fig-3a
  *** Myc-gene mRNA[RPA] is decreased itpo xSmad4
    *** cells: BALBMK in BMS
    *** source: 14993291-Fig-3a
  *** Myc-gene mRNA[RPA] is detectable
    *** cells: HACAT in BMS
    *** partially inhibited by: xSmad3(D408E)"DN" [addition]
    *** source: 14993291-Fig-2c
  *** Myc-gene mRNA[RPA] is unchanged itpo xSmad2
    *** cells: BALBMK in BMS
    *** unaffected by: xSmad4 [addition]
    *** source: 14993291-Fig-3a
  *** Myc-gene mRNA[RTPCR] is decreased itao Tnik [RNAi]
    *** cells: DLD1 in BMS
    *** source: 20530691-Fig-5
  *** Myc-gene mRNA[RTPCR] is decreased itao Tnik [RNAi]
    *** cells: HCT116 in BMS
    *** source: 20530691-Fig-5
  *** Myc-gene mRNA[RTPCR] is detectable
    *** cells: HEK293 in BMLS
    *** unaffected by: Ppp2r5a [RNAi]
    *** source: 16537924-Fig-3a
  *** Myc-gene mRNA[RTPCR] is increased itao Axin1 [RNAi]
    *** cells: HEK293 in BMS
    *** source: 19131971-Fig-2c
  *** Myc-gene promo-reporter[Luc] is decreased itpo xSmad3
    *** cells: mEFs<Smad3~null> in BMS
    *** source: 15241418-Fig-3d
  *** Myc-gene promo-reporter[Luc] is detectable
    *** cells: mEFs<Smad3~null><xSmad3> in BMS
    *** unaffected by: xSmad3(T8V) [substitution]
    *** unaffected by: xSmad3(T179V) [substitution]
    *** partially inhibited by: xSmad3(S213A) [substitution]
    *** inhibited by: xSmad3(T8V/T179V/S213A) [substitution]
    *** source: 15241418-Fig-3d
  *** Myc-gene promo-reporter[Luc] is increased itpo xCtnnb1
    *** cells: PC3U in BMS
    *** source: 15684397-Fig-S1a
  *** Myc-gene promo-reporter[Luc] is increased itpo xSmad7
    *** cells: PC3U in BMS
    *** source: 15684397-Fig-S1a
  *** Myc-gene promo-reporter[Luc] is increased itpo xStam2
    *** cells: HEPG2<xIL2Rb><xIL2Rg><xStat5a> in BMLS "treated with IL2 for 24 hr"
    *** source: 10993906-Fig-6a
  *** Myc-gene promo-reporter[Luc] is increased itpo xStam2
    *** cells: HEPG2<xIL2Rb><xIL2Rg><xStat5a> in BMLS "treated with IL2 for 24 hr"
    *** source: 10993906-Fig-6b
  *** Myc-gene promo-reporter[Luc] is unchanged itpo xStam
    *** cells: BAFB03<xCsf2Ra><xCsf2Ra> in BMLS "IL3-deprived"
    *** source: 9133424-Fig-7d
  *** Myc-gene promo-reporter[Luc] is unchanged itpo xStam
    *** cells: BAFB03<xIL2Rb><xIL2Rg> in BMLS "IL3-deprived"
    *** source: 9133424-Fig-7b
  *** xMyc(1-103)[Gal4-DBD] Gal4-reporter[Luc] is detectable
    *** cells: HELA in BMS
    *** partially reqs: Kat2a [AntiSense]
    *** source: 12660246-Fig-5a
  *** xMyc(1-103)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xKat2a
    *** cells: HELA in BMS
    *** enhanced by: xTrrap [addition]
    *** source: 12660246-Fig-6a
  *** xMyc(1-103)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xKat2a
    *** cells: HELA in BMS
    *** inhibited by: xMyc(41-143) [substitution]
    *** source: 12660246-Fig-6a
  *** xMyc(1-103)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xTrrap
    *** cells: HELA in BMS
    *** enhanced by: xKat2a [addition]
    *** source: 12660246-Fig-6a
  *** xMyc(1-103)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xTrrap
    *** cells: HELA in BMS
    *** inhibited by: xMyc(41-143) [substitution]
    *** source: 12660246-Fig-6a
  *** xMyc(1-103)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xTrrap
    *** cells: HELA in BMS
    *** inhibited by: xTrrap(1899-2401) [substitution]
    *** source: 12660246-Fig-5c
  *** xMyc(1-262)[Gal4-DBD] Gal4-reporter[Luc] is detectable
    *** cells: HELA in BMS
    *** partially reqs: Kat2a [AntiSense]
    *** source: 12660246-Fig-5a
  *** rMyc[32P] phos[32P-ATP] is unchanged by rP38a
    *** cells: none
    *** source: 7535770-Fig-1a
  *** rMyc[35S] boundby[WB] rPias2(269-803)[GST] is detectable
    *** cells: none
    *** inhibited by: rMyc(del(370-412))"delHLH" [substitution]
    *** source: 9312026-Fig-2a
  *** rMyc[35S] upshift[WBMS] is unchanged by rErk2
    *** cells: none
    *** comment: reaction mix also contains rUbiq, rUbe1, rUbe2d1, rFbxw7
    *** source: 15103331-Fig-5b
  *** rMyc[35S] upshift[WBMS] is undetectable
    *** cells: none
    *** comment: reaction mix contains rFbxw2, rUbiq, rUbe1, rUbe2d1, and rGsk3b
    *** inhibited by: rMyc(T58A) [substitution]
    *** source: 15103331-Fig-5c
  *** rMyc[Ab] boundby[WB] rAxin1[tAb] is detectable
    *** cells: none
    *** source: 19131971-Fig-1c
  *** Myc[Ab] boundto(E2f2-gene)[ChIP] is decreased itpo xHbp1
    *** cells: HEK293 in BMLS
    *** source: 20008325-Fig-3c
  *** Myc[Ab] boundto(E2f2-gene)[ChIP] is increased itao Hbp1 [RNAi]
    *** cells: HEK293 in BMLS
    *** source: 20008325-Fig-3c
  *** Myc[Ab] boundto(Ncl-gene)[ChIP] is decreased itpo xHbp1
    *** cells: HEK293 in BMLS
    *** source: 20008325-Fig-3c
  *** Myc[Ab] boundto(Ncl-gene)[ChIP] is increased itao Hbp1 [RNAi]
    *** cells: HEK293 in BMLS
    *** source: 20008325-Fig-3c
  *** Myc[Ab] copptby[WB] Kat2a[Ab] is undetectable
    *** cells: HEK293 in BMS
    *** source: 10611234-Fig-5b
  *** Myc[Ab] copptby[WB] Sp1[Ab] is undetectable
    *** cells: HEK293 in BMS
    *** source: 20008325-Fig-1d
  *** xMyc[Ab] copptby[WB] xAxin1[tAb] is detectable
    *** cells: HEK293<xAxin1><xMyc> in BMS
    *** inhibited by: xAxin1(1-594)"Ex2-6" [substitution]
    *** inhibited by: xAxin1(595-862)"Ex6-11" [substitution]
    *** inhibited by: xAxin1(del(340-764))"delEx4-9" [substitution]
    *** source: 19131971-Fig-6b
  *** xMyc[Ab] copptby[WB] xAxin1[tAb] is detectable
    *** cells: HEK293<xAxin1><xMyc> in BMS
    *** inhibited by: xAxin1(1-594)"Ex2-6" [substitution]
    *** unaffected by: xAxin1(1-651)"Ex2-7" [substitution]
    *** unaffected by: xAxin1(1-728)"Ex2-8" [substitution]
    *** unaffected by: xAxin1(1-764)"Ex2-9" [substitution]
    *** source: 19131971-Fig-6c
  *** xMyc[Ab] copptby[WB] xAxin1[tAb] is detectable
    *** cells: HEK293<xAxin1><xMyc> in BMS
    *** inhibited by: xAxin1(del(340-418))"delEx4-8" [substitution]
    *** source: 19131971-Fig-6d
  *** xMyc[Ab] copptby[WB] xAxin1[tAb] is detectable
    *** cells: HEK293<xAxin1><xMyc> in BMS
    *** partially inhibited by: xAxin1(del(340-418))"delEx4-5" [substitution]
    *** partially inhibited by: xAxin1(del(372-418))"delEx5" [substitution]
    *** source: 19131971-Fig-7b
  *** xMyc[Ab] copptby[WB] xAxin1[tAb] is detectable
    *** cells: HEK293<xAxin1><xMyc> in BMS
    *** partially inhibited by: xAxin1(del(729-764))"isoform2" [substitution]
    *** partially inhibited by: xAxin1(del(652-764))"delEx8-9" [substitution]
    *** source: 19131971-Fig-6e
  *** xMyc[Ab] copptby[WB] xAxin1[tAb] is detectable
    *** cells: HEK293<xAxin1><xMyc> in BMS
    *** source: 19131971-Fig-1a
  *** xMyc[Ab] copptby[WB] xAxin1[tAb] is detectable
    *** cells: HEK293<xAxin1><xMyc> in BMS
    *** source: 19131971-Fig-1d
  *** xMyc[Ab] copptby[WB] xBtrc[tAb] is detectable 
    *** cells: HEK293<xMyc><xMax><xBtrc> in BMS
    *** source: 15150404-Fig-2a
  *** xMyc[Ab] copptby[WB] xFbxw8[tAb] is detectable 
    *** cells: HEK293<xMyc><xMax><xFbxw8> in BMS
    *** source: 15150404-Fig-2a
  *** Myc[Ab] copptby[WB] xKat2a[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 12660246-Fig-1a
  *** xMyc[Ab] copptby[WB] xPias2[Ab] is detectable
    *** cells: HELA in BMS
    *** source: 9312026-Fig-2b
  *** xMyc[Ab] copptby[WB] xPin1[His] is detectable
    *** cells: HEK293 in BMLS
    *** unaffected by: xMyc(T58A) [substitution]
    *** unaffected by: xMyc(T62A) [substitution]
    *** source: 15048125-Fig-4b
  *** xMyc[Ab] copptby[WB] xPpp2ca[tAb] is detectable
    *** cells: HEK293<xMyc> in BMLS
    *** source: 16537924-Fig-4a
  *** xMyc[Ab] copptby[WB] xPpp2r5a[tAb] is detectable
    *** cells: HEK293<xMyc> in BMLS
    *** enhanced by: xMyc(T58A) [substitution]
    *** unaffected by: xMyc(T58E) [substitution] 
    *** unaffected by: xMyc(S62A) [substitution] 
    *** unaffected by: xMyc(S62D) [substitution] 
    *** source: 16537924-Fig-5b
  *** xMyc[Ab] copptby[WB] xPpp2r5a[tAb] is detectable
    *** cells: HEK293<xMyc> in BMLS
    *** source: 16537924-Fig-3c
  *** xMyc[Ab] copptby[WB] xPpp2r5b[tAb] is undetectable
    *** cells: HEK293<xMyc> in BMLS
    *** source: 16537924-Fig-4c
  *** xMyc[Ab] copptby[WB] xPpp2r5c1[tAb] is undetectable
    *** cells: HEK293<xMyc> in BMLS
    *** source: 16537924-Fig-4c
  *** xMyc[Ab] copptby[WB] xPpp2r5c3[tAb] is undetectable
    *** cells: HEK293<xMyc> in BMLS
    *** source: 16537924-Fig-4c
  *** xMyc[Ab] copptby[WB] xPpp2r5d[tAb] is undetectable
    *** cells: HEK293<xMyc> in BMLS
    *** source: 16537924-Fig-4c
  *** xMyc[Ab] copptby[WB] xPpp2r5e[tAb] is undetectable
    *** cells: HEK293<xMyc> in BMLS
    *** source: 16537924-Fig-4c
  *** xMyc[Ab] locatedin(subnuclear-bodies)[IHC] is detectable
    *** cells: COS7<xMyc> in BMS
    *** inhibited by: xMyc(T58A) [substitution]
    *** comment: xMyc does not colocalize [IHC] with Ki67 in the nucleus
    *** source: 14563837-Fig-5
  *** Myc[Ab] prot-exp[WB] is decreased itao Tnik [RNAi]
    *** cells: SW480 in BMS
    *** source: 21710659-Fig-1a
  *** xMyc[Ab] prot-exp[WB] is decreased itpo xAxin1
    *** cells: HEK293<xMyc> in BMLS
    *** source: 19131971-Fig-3b
  *** xMyc[Ab] prot-exp[WB] is decreased itpo xAxin1
    *** cells: HEK293<xMyc> in BMS
    *** reversed by: xMyc(T58A) [substitution]
    *** reversed by: xMyc(S62A) [substitution]
    *** source: 19131971-Fig-5d
  *** Myc[Ab] prot-exp[WB] is decreased itpo xSmad3
    *** cells: mEFs<Smad3~null> in BMS
    *** enhanced by: xSmad3(T8V) [substitution]
    *** enhanced by: xSmad3(T179V) [substitution]
    *** enhanced by: xSmad3(S213A) [substitution]
    *** enhanced by: xSmad3(T8V/T179V/S213A) [substitution]
    *** source: 15241418-Fig-4e
  *** Myc[Ab] prot-exp[WB] is detectable
    *** cells: HCT116 in BMLS
    *** partially reqs: Hdac6 [RNAi]
    *** source: 18356165-Fig-2f
  *** Myc[Ab] prot-exp[WB] is detectable
    *** cells: HCT116 in BMS
    *** partially reqs: Ctnnb1 [RNAi]
    *** source: 18356165-Fig-1a
  *** xMyc[Ab] prot-exp[WB] is detectable
    *** cells: HEK293 in BMLS
    *** unaffected by: Hbp1 [RNAi]
    *** source: 20008325-Fig-2c
  *** Myc[Ab] prot-exp[WB] is detectable
    *** cells: HEK293 in BMLS
    *** unaffected by: Hbp1 [RNAi]
    *** source: 20008325-Fig-3d
  *** Myc[Ab] prot-exp[WB] is detectable
    *** cells: HELA in BMS
    *** enhanced by: ALLN [addition]
    *** enhanced by: ALLM [addition]
    *** enhanced by: MG132 [addition]
    *** enhanced by: E64 [addition]
    *** enhanced by: PSI [addition]
    *** source: 9927431-Fig-1b
  *** Myc[Ab] prot-exp[WB] is detectable
    *** cells: HELA in BMS
    *** unaffected by: Gsk3s [RNAi] 
    *** unaffected by: Cdk2 [RNAi] 
    *** source: 15150404-Fig-4a
  *** Myc[Ab] prot-exp[WB] is detectable
    *** cells: U2OS in BMS
    *** enhanced by: ALLN [addition]
    *** unaffected by: ALLM [addition]
    *** enhanced by: MG132 [addition]
    *** unaffected by: E64 [addition]
    *** enhanced by: PSI [addition]
    *** source: 9927431-Fig-1b
  *** Myc[Ab] prot-exp[WB] is increased itao Axin1 [RNAi]
    *** cells: HEK293 in BMS
    *** source: 19131971-Fig-2b
  *** xMyc[Ab] prot-exp[WB] is increased itao Pin1 [KO]
    *** cells: mEFs in BMLS
    *** reversed by: xMyc(T58A) [substitution]
    *** source: 15048125-Fig-5d
  *** xMyc[Ab] prot-exp[WB] is increased itao Pin1 [KO]
    *** cells: mEFs in BMLS
    *** reversed by: xPin1 [addition]
    *** source: 15048125-Fig-5a
  *** xMyc[Ab] prot-exp[WB] is increased itao Ppp2c? [RNAi]
    *** cells: HEK293 in BMLS
    *** source: 15048125-Fig-3c
  *** Myc[Ab] prot-exp[WB] is increased itao Skp2 [KO]
    *** cells: mESCs in BMS
    *** source: 15103331-Fig-5c
  *** Myc[Ab] prot-exp[WB] is increased itao Skp2 [RNAi]
    *** cells: HELA in BMS
    *** source: 15103331-Fig-4b
  *** Myc[Ab] prot-exp[WB] is increased itpo xHdac6
    *** cells: SW480 in BMLS
    *** source: 18356165-Fig-2h
  *** Myc[Ab] prot-exp[WB] is increased itpo xPin1
    *** cells: MCF7 in BMS
    *** source: 11533658-Fig-1c
  *** xMyc[Ab] prot-exp[WB] is unchanged itpo xBtrc
    *** cells: HEK293<xMyc><xMax> in BMS
    *** source: 15150404-Fig-2a
  *** xMyc[Ab] prot-exp[WB] is unchanged itpo xFbxw8
    *** cells: HEK293<xMyc><xMax> in BMS
    *** source: 15150404-Fig-2a
  *** xMyc[Ab] prot-exp[WB] is unchanged itpo xHbp1
    *** cells: HEK293 in BMLS
    *** source: 20008325-Fig-2c
  *** xMyc[Ab] prot-stability[35S-pulse-chase] is increased itao Pin1 [KO]
    *** cells: mEFs in BMLS
    *** source: 15048125-Fig-5b
  *** xMyc[Ab] prot-stability[CHX-WB] is detectable
    *** cells: HEK293<xMyc> in BMLS
    *** repressed by: Ppp2r5a [RNAi]
    *** source: 16537924-Fig-3b
  *** xMyc[Ab] prot-stability[CHX-WB] is increased itao Axin1 [RNAi]
    *** cells: HEK293<xMyc> in BMLS
    *** source: 19131971-Fig-2g
  *** xMyc[Ab] snaggedby[WB] oligo[biotin] is detectable
    *** cells: HEK293T<xGfi1><xZbtb17><xMyc> in BMS
    *** reqs: xZbtb17 [omission]
    *** source: 20190815-Fig-6b
  *** xMyc[Ab] snaggedby[WB] oligo[biotin] is detectable
    *** cells: HEK293T<xZbtb17><xMyc> in BMS
    *** partially inhibited by: xGfi1 [addition]
    *** source: 20190815-Fig-6b
  *** xMyc[Ab] snaggedby[WB] rPin1[GST] is detectable
    *** cells: REF52 in BMLS
    *** inhibited by: rPin1(W33A) [substitution]
    *** unaffected by: rPin1(C109A)"CIA" [substitution]
    *** source: 15048125-Fig-4a
  *** xMyc[Ab] ubiq[UbAb-ppt] is increased itpo xAxin1
    *** cells: HEK293<xMyc> in BMLS "treated with proteasome inhibitors"
    *** source: 19131971-Fig-3a
  *** xMyc[Ab]IP phos(S62)[phosAb] is decreased by pPP2a
    *** cells: none
    *** IPfrom: REF52 in BMLS "treated with MG132 and Okadaic-acid for 4 hr"
    *** reversed by: xMyc(T58A) [substitution]
    *** source: 15048125-Fig-3b
  *** xMyc[Ab]IP phos(S62)[phosAb] is decreased by pPP2a
    *** cells: none
    *** IPfrom: REF52<xHras(Q12V)> in BMLS
    *** source: 15048125-Fig-3a
  *** xMyc[Ab]IP phos(S62)[phosAb] is detectable-but unchanged by rPpp1c?
    *** cells: none
    *** IPfrom: REF52<xHras(Q12V)> in BMLS
    *** source: 15048125-Fig-3a
  *** xMyc[Ab]IP phos(T58)[phosAb] is detectable-but unchanged by pPP2a
    *** cells: none
    *** IPfrom: REF52<xHras(Q12V)> in BMLS
    *** source: 15048125-Fig-3a
  *** xMyc[Ab]IP phos(T58)[phosAb] is detectable-but unchanged by rPpp1c?
    *** cells: none
    *** IPfrom: REF52<xHras(Q12V)> in BMLS
    *** source: 15048125-Fig-3a
  *** xMyc[phosAb] phos(S62)[phosAb] is detectable
    *** cells: HEK293<xMyc> in BMS
    *** unaffected by: Axin1 [RNAi]
    *** source: 19131971-Fig-2f
  *** Myc[phosAb] phos(S62)[phosAb] is detectable
    *** cells: HEPG2 in BMS
    *** source: 19131971-Fig-7a
  *** Myc[phosAb] phos(S62)[phosAb] is detectable
    *** cells: SNU475<Axin1~null> in BMS
    *** source: 19131971-Fig-7a
  *** xMyc[phosAb] phos(T58)[phosAb] is detectable
    *** cells: HEK293<xMyc> in BMS
    *** reqs: Axin1 [RNAi]
    *** source: 19131971-Fig-2f
  *** Myc[phosAb] phos(T58)[phosAb] is detectable
    *** cells: HEPG2 in BMS
    *** source: 19131971-Fig-7a
  *** Myc[phosAb] phos(T58)[phosAb] is undetectable
    *** cells: SNU475<Axin1~null> in BMS
    *** source: 19131971-Fig-7a
  *** Myc[phosAb] phos(T58/S62)[phosAb] is detectable
    *** cells: HEK293T in BMS "treated with MG132 for 6 hr"
    *** inhibited by: GSK3inhibitorII [cotreatment]
    *** source: 15103331-Fig-3e
  *** xMyc[tAb] copptby[WB] xHbp1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 20008325-Fig-1c
  *** xMyc[tAb] copptby[WB] xHbp1[tAb] is detectable
    *** cells: HEK293<xMyc><xHbp1> in BMS
    *** inhibited by: xHbp1(1-429)"delCT" [substitution]
    *** unaffected by: xHbp1(del(189-393))"delRep" [substitution]
    *** partially inhibited by: xHbp1(1-263) [substitution]
    *** inhibited by: xHbp1(del(356-461)) [substitution]
    *** source: 20008325-Fig-5b
  *** xMyc[tAb] prot-exp[WB] is decreased itpo xPpp2ca
    *** cells: HEK293<xMyc> in BMLS
    *** source: 16537924-Fig-1a
  *** xMyc[tAb] prot-exp[WB] is decreased itpo xPpp2ca
    *** cells: HEK293<xMyc> in BMLS
    *** source: 16537924-Fig-6
  *** xMyc[tAb] prot-exp[WB] is decreased itpo xPpp2r5a
    *** cells: HEK293<xMyc> in BMLS
    *** enhanced by: xPpp2ca [addition]
    *** inhibited by: xPpp2r1a [addition] 
    *** source: 16537924-Fig-6
  *** xMyc[tAb] prot-exp[WB] is detectable
    *** cells: HEK293<xMyc> in BMLS
    *** repressed by: Ppp2ca [RNAi]
    *** unaffected by: Ppp2r2a [RNAi]
    *** source: 16537924-Fig-2a
  *** xMyc[tAb] prot-exp[WB] is detectable
    *** cells: HEK293<xMyc> in BMLS
    *** repressed by: Ppp2r1a [RNAi]
    *** repressed by: Ppp2r5a [RNAi]
    *** unaffected by: Ppp2r5b [RNAi]
    *** unaffected by: Ppp2r5c [RNAi]
    *** unaffected by: Ppp2r5d [RNAi]
    *** unaffected by: Ppp2r5e [RNAi]
    *** source: 16537924-Fig-2c
  *** xMyc[tAb] prot-exp[WB] is detectable
    *** cells: HEK293<xMyc> in BMLS
    *** repressed by: Ppp2r5a [RNAi]
    *** source: 16537924-Fig-3a
  *** xMyc[tAb] prot-exp[WB] is increased itpo xPpp2r1a
    *** cells: HEK293<xMyc> in BMLS
    *** source: 16537924-Fig-6
  *** xMyc[tAb] prot-exp[WB] is increased itpo xST!SV40
    *** cells: HEK293<xMyc> in BMLS
    *** source: 16537924-Fig-1a
  *** xMyc[tAb]IP prot-stability[35S-pulse-chase] is increased itao Skp2 [KO]
    *** cells: mESCs in BMS
    *** source: 15103331-Fig-5d
  *** xMyc[tAb]IP prot-stability[35S-pulse-chase] is increased itao Skp2 [RNAi]
    *** cells: HEK293T in BMS
    *** unaffected by: xMyc(T58A/S62A) [substitution]
    *** source: 15103331-Fig-4c
  *** MycRE-reporter[Luc] is decreased itpo xAxin1
    *** cells: HEK293<xMyc> in BMS
    *** partially reversed by: xAxin1(del(340-418))"delEx4-5" [substitution]
    *** partially reversed by: xAxin1(del(372-418))"delEx5" [substitution]
    *** source: 19131971-Fig-7c
  *** MycRE-reporter[Luc] is decreased itpo xAxin1
    *** cells: U2OS in BMLS
    *** source: 19131971-Fig-4b
  *** MycRE-reporter[Luc] is increased itao Hbp1 [RNAi]
    *** cells: HEK293 in BMLS
    *** source: 20008325-Fig-2e
  *** MycRE-reporter[Luc] is increased itao Ppp2r5a [RNAi]
    *** cells: HEK293<xMyc> in BMLS
    *** source: 16537924-Fig-7c
  *** MycRE-reporter[Luc] is increased itpo xMyc
    *** cells: HEK293 in BMLS
    *** inhibited by: xHbp1 [addition]
    *** unaffected by: xHbp1(1-429)"delCT" [substitution]
    *** unaffected by: xHbp1(del(189-393))"delRep" [substitution]
    *** partially inhibited by: xHbp1(1-263) [substitution]
    *** partially inhibited by: xHbp1(del(356-461)) [substitution]
    *** source: 20008325-Fig-5d
  *** MycRE-reporter[Luc] is increased itpo xMyc
    *** cells: HEK293 in BMLS
    *** partially inhibited by: xAxin1 [addition]
    *** source: 19131971-Fig-4b
  *** MycRE-reporter[Luc] is increased itpo xMyc
    *** cells: HEK293 in BMLS
    *** partially inhibited by: xHbp1 [addition]
    *** source: 20008325-Fig-2a
  *** MycRE-reporter[Luc] is increased itpo xMyc
    *** cells: HEK293 in BMS
    *** inhibited by: xFbxw7g [addition]
    *** source: 15150404-Fig-1e
  *** MycRE-reporter[Luc] is increased itpo xMyc
    *** cells: U2OS in BMLS
    *** bkg inhibited by: xAxin1 [addition]
    *** source: 19131971-Fig-4b
  *** MycRE-reporter[Luc] is unchanged itpo xHbp1
    *** cells: HEK293 in BMLS
    *** source: 20008325-Fig-5d
*** Myd88--
  *** Myd88-gene mRNA[Northern] is detectable
    *** cells: hTh1 in BMS
    *** source: 10925275-Fig-7
  *** Myd88-gene mRNA[Northern] is detectable
    *** cells: hTh2 in BMS
    *** source: 10925275-Fig-7
  *** Myd88-gene mRNA[Northern] is detectable
    *** cells: mSpCs in BMS "activated with anti-Cd3 for 48 hr"
    *** does not req: Stat4 [KO]
    *** source: 11120802-Fig-4a
  *** xMyd88[tAb] copptby[WB] xSpp1[tAb] is detectable
    *** cells: HEK293<xSpp1><xMyd88><xTLR9> in BMS "treated with CpG-1668 (3 hr)"
    *** source: 16604075-Fig-4c
  *** xMyd88[tAb] copptby[WB] xTLR2[tAb] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xTLR3(A795H) [substitution]
    *** unaffected by: PolyIC (tnr) [stim]
    *** source: 12539043-Fig-S2
  *** xMyd88[tAb] copptby[WB] xTLR3[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12539043-Fig-S2
  *** xMyd88[tAb] copptby[WB] xTLR4[Ab] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: xTLR4(P714H)"CA" [substitution]
    *** unaffected by: xMyd88(P200H) [substitution]
    *** source: 12888566-Fig-3b,4a
  *** xMyd88[tAb] copptby[WB] xTLR4[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 9625770-Fig-2a
  *** xMyd88[tAb] copptby[WB] xTLR4[tAb] is detectable
    *** cells: HEK293<xMd2> in BMS
    *** source: 12539043-Fig-S2
  *** xMyd88[tAb] snaggedby[WB] rTLR4[GST] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: rTLR4(P714H)"CA" [substitution]
    *** partially inhibited by: xMyd88(P200H) [substitution]
    *** source: 12888566-Fig-3a
  *** xMyd88[tAb]IP ubiq[tUbAb] is unchanged itpo xSocs1
    *** cells: HEK293T<xUbiq> in BMS "treated with MG132"
    *** source: 16415872-Fig-3a
  *** Nab2-gene mRNA[RTPCR] is increased itpo xEgr1
    *** cells: NEURO2A in BMS
    *** enhanced by: xEgr1(mnr)"Nab-insensitive" [substitution]
    *** source: 11111043-Fig-5b
  *** Nab2-gene mRNA[RTPCR] is unchanged itpo xEgr2
    *** cells: NEURO2A in BMS
    *** source: 11111043-Fig-5b
*** Nalp1--
  *** xNalp1[tAb] copptby[WB] xCasp1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 15107016(D)
  *** xNalp1[tAb] copptby[WB] xIpaf[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 15107016(D)
*** Nbs1--
  *** rNbs1(1-348)[tAb] boundby[WB] rMdc1(296-340){phos}[GST] is detectable
    *** cells: none
    *** comment: rMdc1(296-340) was phosed by rCsnk2
    *** inhibited by: rMdc1(296-340) [substitution]
    *** source: 18583988-Fig-3b
  *** rNbs1(1-348)[tAb] boundby[WB] rMdc1(296-340){phos}[GST] is detectable
    *** cells: none
    *** comment: rMdc1(296-340) was phosed by rCsnk2
    *** inhibited by: rNbs1(R28A) [substitution]
    *** inhibited by: rNbs1(H45A) [substitution]
    *** inhibited by: rNbs1(K160M) [substitution]
    *** source: 18583988-Fig-3b
  *** rNbs1[35S] boundby[WB] rMdc1(181-480){phos}[GST] is detectable
    *** cells: none
    *** comment: rMdc1(181-480) was phosed with rCsnk2
    *** inhibited by: rMdc1(181-480/mnr)"12A"{phos} [substitution]
    *** inhibited by: rMdc1(181-480) [substitution]
    *** source: 18411307-Fig-4b
  *** rNbs1[35S] boundby[WB] rMdc1(181-480){phos}[GST] is detectable
    *** cells: none
    *** comment: rMdc1(181-480) was phosed with rCsnk2
    *** inhibited by: rNbs1(mnr)"R28" [substitution]
    *** source: 18411307-Fig-4b
  *** rNbs1[Ab] boundby[WB] sMdc1(325-340){phos(S329/T331)}[biotin] is detectable
    *** cells: none
    *** comment: reaction also contains rRad50 and rMre11
    *** source: 18583988-Fig-3a
  *** Nbs1[Ab] copptby[WB] Atrip[Ab] is detectable
    *** cells: HELA in BMS "nuclear-extract"
    *** comment: IP was performed in the presence of linear dsDNA
    *** source: 15758953-Fig-S4b
  *** Nbs1[Ab] copptby[WB] Atrip[Ab] is undetectable
    *** cells: HELA in BMS
    *** source: 16431910-Fig-S1
  *** Nbs1[Ab] copptby[WB] Ku80[Ab] is undetectable
    *** cells: HELA in BMS "nuclear-extract"
    *** comment: IP was performed in the presence of linear dsDNA
    *** source: 15758953-Fig-S4b
  *** Nbs1[Ab] copptby[WB] Mdc1[Ab] is detectable-but unchanged irt IR (1 hr)
    *** cells: U2OS in BMS
    *** source: 18411307-Fig-1a
  *** Nbs1[Ab] copptby[WB] Mrc1[Ab] is detectable
    *** cells: HELA in BMS "nuclear-extracts"
    *** source: 12607003-Fig-1c
  *** Nbs1[Ab] copptby[WB] xMdc1(1-1100)[tAb] is detectable
    *** cells: U2OS<Mdc1~kd><xMdc1(1-1100)> in BMS
    *** unaffected by: xMdc1(1-600) [substitution]
    *** unaffected by: xMdc1(1-500) [substitution]
    *** unaffected by: xMdc1(1-400) [substitution]
    *** partially inhibited by: xMdc1(1-310) [substitution]
    *** inhibited by: xMdc1(1-250) [substitution]
    *** inhibited by: xMdc1(1-200) [substitution]
    *** inhibited by: xMdc1(50-135) [substitution]
    *** source: 18411307-Fig-1c
  *** Nbs1[Ab] copptby[WB] xMdc1(1-1100)[tAb] is detectable
    *** cells: U2OS<Mdc1~kd><xMdc1(1-1100)> in BMS
    *** unaffected by: xMdc1(136-1100)"dFHA" [substitution]
    *** inhibited by: xMdc1(del(210-460)) [substitution]
    *** unaffected by: xMdc1(210-460)"SDT" [substitution]
    *** unaffected by: xMdc1(210-360)"SDT1" [substitution]
    *** unaffected by: xMdc1(310-460)"SDT2" [substitution]
    *** source: 18411307-Fig-2c
  *** xNbs1[Ab] copptby[WB] xMdc1(1-1100)[tAb] is detectable
    *** cells: U2OS<Mdc1~kd><xMdc1(1-1100)><xNbs1> in BMS
    *** inhibited by: xNbs1(mnr)"R28" [substitution]
    *** inhibited by: xNbs1(mnr)"delC" [substitution]
    *** inhibited by: xNbs1(S278A/S343A/S397A)"delC" [substitution]
    *** source: 18411307-Fig-1e
  *** Nbs1[Ab] copptby[WB] xMdc1(1-1100)[tAb] is detectable
    *** cells: U2OS<xMdc1(1-1100)> in BMS
    *** unaffected by: xMdc1(1-1100/S299A/T301A) [substitution]
    *** unaffected by: xMdc1(1-1100/S453A/T455A) [substitution]
    *** partially inhibited by: xMdc1(1-1100/S299A/T301A/S453A/T455A) [substitution]
    *** inhibited by: xMdc1(1-1100/S299A/T301A/S329A/T331A/S402A/T404A/S453A/T455A) [substitution]
    *** source: 18411307-Fig-7a
  *** Nbs1[Ab] copptby[WB] xMdc1(1-1100)[tAb] is detectable
    *** cells: U2OS<xMdc1(1-1100)> in BMS
    *** unaffected by: xMdc1(1-1100/T699A/T719A/T752A) [substitution]
    *** source: 18001824-Fig-S3b
  *** Nbs1[Ab] copptby[WB] xMdc1[tAb] is detectable
    *** cells: HEK293T<xMdc1> in BMS
    *** inhibited by: xMdc1(del(196-506)) [substitution] 
    *** source: 18583988-Fig-4b
  *** xNbs1[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: NBS1LBI<Nbs1~fmut><xNbs1> in BMS
    *** source: 16478990-Fig-2b
  *** Nbs1[Ab] prot-exp[WB] is detectable
    *** cells: HCT116 in BMS
    *** reqs: Rad50 [RNAi]
    *** source: 16087684-Fig-1a
  *** Nbs1[Ab] prot-exp[WB] is detectable
    *** cells: HEK293T in BMS
    *** partially reqs: Rad50 [RNAi]
    *** source: 16087684-Fig-1a
  *** Nbs1[Ab] prot-exp[WB] is detectable
    *** cells: HELA in BMS
    *** does not req: Mdc1 [RNAi]
    *** source: 15201865-Fig-5a
  *** xNbs1[Ab] snaggedby[WB] dsDNA[biotin] is detectable
    *** cells: NBS1LBI<Nbs1~fmut><xNbs1> in BMS
    *** unaffected by: xNbs1(1-734)"delC" [substitution]
    *** source: 15758953-Fig-2a
  *** Nbs1[Ab] snaggedby[WB] rMdc1(296-340){phos}[GST] is detectable
    *** cells: HELA in BMS "nuclear-extract"
    *** comment: rMdc1(296-340) was phosed by rCsnk2
    *** inhibited by: rMdc1(296-340/T301A/T331A) [substitution]
    *** source: 18583988-Fig-2d
  *** Nbs1[Ab] snaggedby[WB] rMdc1(296-340){phos}[GST] is detectable
    *** cells: MRC5 in BMS
    *** comment: rMdc1(296-340) was phosed by rCsnk2
    *** inhibited by: rMdc1(296-340) [substitution]
    *** source: 18583988-Fig-3c
  *** xNbs1[Ab] snaggedby[WB] rMdc1(296-340){phos}[GST] is detectable
    *** cells: NBS1LBI<Nbs1~fmut><xNbs1> in BMS
    *** comment: rMdc1(296-340) was phosed by rCsnk2
    *** inhibited by: rMdc1(296-340) [substitution]
    *** source: 18583988-Fig-3c
  *** xNbs1[Ab] snaggedby[WB] rMdc1(296-340){phos}[GST] is detectable
    *** cells: NBS1LBI<Nbs1~fmut><xNbs1> in BMS
    *** comment: rMdc1(296-340) was phosed by rCsnk2
    *** inhibited by: xNbs1(R28A) [substitution]
    *** source: 18583988-Fig-3c
  *** Nbs1[Ab] snaggedby[WB] sH2ax(123-143){phos(S140)}[GST] is detectable
    *** cells: HELA in BMS "nuclear-extracts"
    *** inhibited by: sH2ax(123-143) [substitution]
    *** source: 16377563-Fig-1b
  *** Nbs1[Ab] snaggedby[WB] sH2ax(124-143){phos(S140)}[biotin] is detectable
    *** cells: HELA in BMS
    *** inhibited by: sH2ax(124-143) [substitution]
    *** source: 15201865-Fig-5b
  *** Nbs1[Ab] snaggedby[WB] sH2ax(124-143){phos(S140)}[biotin] is detectable
    *** cells: HELA in BMS
    *** reqs: Mdc1 [RNAi]
    *** source: 15201865-Fig-5b
  *** Nbs1[Ab] snaggedby[WB] sH2ax(134-143){phos(S140)}[biotin] is detectable
    *** cells: HELA in BMS "nuclear-extract"
    *** inhibited by: sH2ax(134-143) [substitution]
    *** source: 18583988-Fig-1c
  *** Nbs1[Ab] snaggedby[WB] sMdc1(325-340){phos(S329/T331)}[biotin] is detectable
    *** cells: HELA in BMS "nuclear-extract"
    *** inhibited by: sMdc1(325-340) [substitution]
    *** source: 18583988-Fig-1c
  *** xNbs1[Ab]IP phos(S343)[phosAb] is detectable
    *** cells: NBS1LBI<Nbs1~fmut><xNbs1> in BMS
    *** unaffected by: xNbs1(1-652) [substitution]
    *** inhibited by: xNbs1(401-754) [substitution]
    *** inhibited by: xNbs1(S278A/S343A) [substitution]
    *** source: 15234984-Fig-3a
  *** xNbs1[Ab]IP phos(S343)[phosAb] is detectable
    *** cells: NBS1LBI<Nbs1~fmut><xNbs1> in BMS
    *** unaffected by: xNbs1(1-652) [substitution]
    *** inhibited by: xNbs1(401-754) [substitution]
    *** inhibited by: xNbs1(S278A/S343A) [substitution]
    *** source: 15234984-Fig-3b
  *** Nbs1[Ab]IP prot-exp[WB] is detectable
    *** cells: D6809<Mre11~fmut><xMre11> in BMS
    *** reqs: xMre11 [omission]
    *** source: 16478990-Fig-4b
*** Nck1--
  *** xNck1[Ab] copptby[WB] Pak1[Ab] is detectable
    *** cells: COS7 in BMS
    *** source: 8824201-Fig-3a
  *** Nck1[Ab] copptby[WB] Tnk2[Ab] is undetectable
    *** cells: HER14 in BMLS
    *** source: 16777958-Fig-3a
  *** Nck1[Ab] copptby[WB] xDok2[tAb] is increased itpo xLyn
    *** cells: HEK293T in BMS
    *** inhibited by: xDok2(Y351F) [substitution]
    *** source: 10428862-Fig-8b
  *** Nck1[Ab] copptby[WB] xTnik[tAb] is detectable
    *** cells: HEK293T<xTnik> in BMS
    *** inhibited by: xTnik(1-306)"N1" [substitution]
    *** unaffected by: xTnik(1-1017)"N2" [substitution]
    *** unaffected by: xTnik(306-1360)"C1" [substitution]
    *** inhibited by: xTnik(1017-1360)"C2" [substitution]
    *** unaffected by: xTnik(306-1017)"M" [substitution]
    *** source: 10521462-Fig-4b
  *** Nck1[Ab] copptby[WB] xTnik[tAb] is detectable
    *** cells: HEK293T<xTnik> in BMS
    *** source: 10521462-Fig-4a
  *** xNck1[tAb] copptby[WB] xRalGps1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 10747847-Fig-4c
  *** xNck1[tAb] copptby[WB] xUsp6nl[tAb] is undetectable
    *** cells: COS in BMLS
    *** unaffected by: Egf (10 min) [stim]
    *** source: 12399475-Fig-4a
*** Nckipsd--
*** Ncl--
  *** Ncl-gene mRNA[RTPCR] is decreased itpo xHbp1
    *** cells: HEK293 in BMLS
    *** reversed by: xMyc [addition]
    *** source: 20008325-Fig-3f
  *** Ncl-gene mRNA[RTPCR] is increased itao Hbp1 [RNAi]
    *** cells: HEK293 in BMLS
    *** source: 20008325-Fig-3e
  *** Ncl-gene mRNA[RTPCR] is increased itpo xMyc
    *** cells: HEK293 in BMLS
    *** bkg inhibited by: xHbp1 [addition]
    *** source: 20008325-Fig-3f
  *** Ncl[Ab] colocwith[IHC] Stau1[Ab] is detectable
    *** cells: SHSY5Y in BMS "differentiated with retinoic acid for 7 days"
    *** source: 15121898(D)
  *** Ncl[Ab] copptby[WB] xStau1[tAb] is detectable
    *** cells: HEK293T in BMS "infected with vaccinia vTf7-3 virus"
    *** source: 15121898(D)
  *** Ncl[MS] copptby[WB] xStau1[tAb] is detectable
    *** cells: HEK293T in BMS "infected with vaccinia vTf7-3 virus"
    *** source: 15121898(D)
  *** Ncor2[Ab] copptby[WB] Stat3{phos}[phosAb] is detectable
    *** cells: KAS61 in BMS "IL6 deprived for 24 hr, treated with IL6 for 10 min"
    *** unaffected by: 15dPGJ2 [pretreatment]
    *** enhanced by: Troglitazone [pretreatment]
    *** unaffected by: Troglitazone + GW9662 [pretreatment]
    *** source: 14975242-Fig-6b
  *** Ndrg1[phosAb] phos(T346/T356/T366)[phosAb] is detectable
    *** cells: HEK293<xSgk1> in BMS
    *** inhibited by: PI103 [pretreatment]
    *** unaffected by: Rapamycin [pretreatment]
    *** source: 18925875-Fig-5a
  *** Ndrg1[phosAb] phos(T346/T356/T366)[phosAb] is detectable
    *** cells: HELA<xSgk1> in BMS
    *** inhibited by: PI103 [pretreatment]
    *** unaffected by: Rapamycin [pretreatment]
    *** source: 18925875-Fig-5c
  *** Ndrg1[phosAb] phos(T346/T356/T366)[phosAb] is detectable
    *** cells: MCF7<xSgk1> in BMS
    *** inhibited by: PI103 [pretreatment]
    *** unaffected by: Rapamycin [pretreatment]
    *** source: 18925875-Fig-5b
  *** Ndrg1[phosAb] phos(T346/T356/T366)[phosAb] is detectable
    *** cells: mEFs in BMS
    *** reqs: Mlst8 [RNAi]
    *** source: 18925875-Fig-2
  *** Ndrg1[phosAb] phos(T346/T356/T366)[phosAb] is detectable
    *** cells: mEFs in BMS
    *** reqs: Rictor [RNAi]
    *** source: 18925875-Fig-2
  *** Ndrg1[phosAb] phos(T346/T356/T366)[phosAb] is detectable
    *** cells: mEFs in BMS
    *** reqs: Sin1 [RNAi]
    *** source: 18925875-Fig-2
*** Ndufa13--
  *** xNdufa13[tAb] copptby[WB] xStat3[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 14498832-Fig-3
*** Nedd9--
  *** rNedd9(82-398)"SD"[GST] Yphos[pYAb] is increased by xFak2[tAb]IP
    *** cells: none
    *** IPfrom: COS7<xFak2> in BMS
    *** unaffected by: xFak2(Y402F) [substitution]
    *** inhibited by: xFak2(K457R) [substitution]
    *** source: 9242628-Fig-5
  *** rNedd9(626-832)"CT"[GST] Yphos[pYAb] is unchanged by xFak2[tAb]IP
    *** cells: none
    *** IPfrom: COS7<xFak2> in BMS
    *** source: 9242628-Fig-6
  *** Nedd9[Ab] copptby[WB] Bcar1[Ab] is undetectable
    *** cells: hTonsillarBCs in BMS
    *** source: 9020138-Fig-1a
  *** Nedd9[Ab] copptby[WB] CrkL[Ab] is detectable
    *** cells: ARH77 in BMLS
    *** source: 9020138-Fig-5a
  *** Nedd9[Ab] copptby[WB] CrkL[Ab] is detectable
    *** cells: hTonsillarBCs in BMS
    *** source: 9020138-Fig-5a
  *** Nedd9[Ab] copptby[WB] Fyn[Ab] is undetectable
    *** cells: hTonsillarBCs in BMS
    *** source: 9020138-Fig-6a
  *** Nedd9[Ab] copptby[WB] Hck[Ab] is undetectable
    *** cells: hTonsillarBCs in BMS
    *** source: 9020138-Fig-6a
  *** Nedd9[Ab] copptby[WB] Lyn[Ab] is detectable
    *** cells: hTonsillarBCs in BMS
    *** source: 9020138-Fig-6a
  *** xNedd9[Ab]IP Yphos[pYAb] is increased itpo xFak2
    *** cells: COS7<xNedd9> in BMS
    *** source: 9242628-Fig-2c
  *** xNedd9[Ab]IP Yphos[pYAb] is increased itpo xFak2
    *** cells: COS7<xNedd9> in BMS
    *** unaffected by: xFak2(Y402F) [substitution]
    *** inhibited by: xFak2(K457R) [substitution]
    *** source: 9242628-Fig-3b
  *** xNek6[tAb] copptby[WB] xRheb[tAb] is undetectable
    *** cells: HEK293T<xRheb><xNek6> in BMS
    *** source: 15854902-Fig-4a
*** Nemo--
  *** xNemo(sumo)[tAb] locatedin(nucleus)[IHC] is detectable
    *** cells: COS7<xNemo(sumo)> in BMS
    *** reversed by: xIkk2 [addition]
    *** source: 14651848-Fig-4b
  *** xNemo(sumo)[tAb] locatedin(nucleus)[IHC] is detectable
    *** cells: COS7<xNemo(sumo)> in BMS
    *** unaffected by: xNemo(sumo/C417R) [substitution]
    *** unaffected by: xNemo(sumo/K277A/K309A) [substitution]
    *** source: 14651848-Fig-4b
  *** Nemo[Ab] prot-exp[WB] is detectable-but unchanged itao Traf2 [KO]
    *** cells: mEFs in BMS
    *** source: 18997792-Fig-3b
  *** Nemo[Ab] prot-exp[WB] is detectable-but unchanged itao Traf3 [KO]
    *** cells: mEFs in BMS
    *** source: 18997792-Fig-3b
  *** rNemo[Ab] upshift[WBMS] is increased by (rUbiq + pUbe1 + rUbe2d3 + rRnf31 + rRbck1)
    *** cells: none
    *** unaffected by: rUsp5 [addition]
    *** unaffected by: rCyld [addition]
    *** inhibited by: rLprotein!9Viru(mnr)"OTU-domain" [addition]
    *** source: 19675569-Fig-4e
  *** xNemo[Ab] upshift[WBMS] is increased itpo xBcl10
    *** cells: HEK293T in BMS
    *** reqs: Malt1 [RNAi]
    *** reqs: Ubc13 [RNAi]
    *** inhibited by: xNemo(K399R)"ubiq-site-mut" [substitution]
    *** source: 14695475-Fig-3a
  *** Nemo[Ab]IP IVKA(Ikba)[32P-ATP] is increased itpo xAkt1
    *** cells: mEFs in BMS
    *** source: 11733537-Fig-4c
  *** Nemo[Ab]IP IVKA(Ikba)[32P-ATP] is increased itpo xTpl2
    *** cells: HEK293T in BMS
    *** inhibited by: xTpl2(S400A) [substitution]
    *** source: 12138205-Fig-6b
  *** Nemo[Ab]IP IVKA(Ikba)[32P-ATP] is increased itpo xTraf6
    *** cells: HEK293 in BMS
    *** inhibited by: xTraf6(C70A)"E3-mut" [substitution]
    *** partially inhibited by: xTraf6(K124R) [substitution]
    *** source: 17135271-Fig-4b
  *** Nemo[Ab]IP IVKA(Ikba)[32P-ATP] is increased itpo xTraf6
    *** cells: mEFs in BMLS
    *** inhibited by: xTraf6(C70A)"E3-mut" [substitution]
    *** inhibited by: xTraf6(K124R) [substitution]
    *** unaffected by: xTraf6(K133R) [substitution]
    *** unaffected by: xTraf6(K142R) [substitution]
    *** source: 17135271-Fig-6b
  *** Nemo[Ab]IP IVKA(Ikba)[32P-ATP] is unchanged itpo xTp53
    *** cells: SAOS2 in BMS
    *** source: 15073170-Fig-3c
  *** xNemo[Ab]IP ubiq[UbAb] is increased itpo xMalt1
    *** cells: HEK293T in BMS
    *** inhibited by: xNemo(K399R)"ubiq-BS-mut" [substitution]
    *** source: 14695475-Fig-4b
  *** Nemo[phosAb] phos(S376)[phosAb] is increased itpo xIkke
    *** cells: HEK293 in BMS
    *** source: 16199137-Fig-3b
  *** xNemo[tAb] copptby[WB] xAzi2[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 14560022-Fig-2c
  *** xNemo[tAb] copptby[WB] xBcl10[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 11262391-Fig-2a
  *** xNemo[tAb] copptby[WB] xCyld[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 12917689-Fig-1a,1c
  *** xNemo[tAb] copptby[WB] xCyld[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 12917691-Fig-2a
  *** xNemo[tAb] copptby[WB] xRipk1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 10880512-Fig-4a
  *** xNemo[tAb] copptby[WB] xRipk2[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 10880512-Fig-4a
  *** xNemo[tAb] copptby[WB] xTnfaip3[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 10755617(D)
  *** xNemo[tAb] copptby[WB] xTraf2[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 10880512-Fig-4a
  *** xNemo[tAb] copptby[WB] xZfand5[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 14754897-Fig-2a
  *** xNemo[tAb] locatedin(cytoplasm)[IHC] is detectable
    *** cells: COS7<xNemo> in BMS
    *** unaffected by: xIkk2 [addition]
    *** source: 14651848-Fig-4b
  *** xNemo[tAb] locatedin(cytoplasm)[IHC] is detectable
    *** cells: COS7<xNemo> in BMS
    *** unaffected by: xNemo(C417R) [substitution]
    *** unaffected by: xNemo(K277A/K309A) [substitution]
    *** source: 14651848-Fig-4b
  *** xNemo[tAb] upshift[WBMS] is decreased itpo xCyld
    *** cells: HEK293T<xUbiq> in BMS
    *** source: 12917691-Fig-3c,3d,S3b
  *** rNemo[tAb] upshift[WBMS] is increased by (rUbiq + rUbe1 + rUbe2e1 + rCiap1)
    *** cells: none
    *** source: 12867425-Fig-3e
  *** xNemo[tAb] upshift[WBMS] is increased itpo xUbiq
    *** cells: HEK293T in BMS
    *** inhibited by: MG132 [addition]
    *** source: 12917691-Fig-S2
  *** rNemo[tAb] upshift[WBMS] is unchanged by (rUbiq + rUbe1 + rCdc34 + rCiap1)
    *** cells: none
    *** source: 12867425-Fig-3e
  *** rNemo[tAb] upshift[WBMS] is unchanged by (rUbiq + rUbe1 + rUbc13 + rCiap1)
    *** cells: none
    *** source: 12867425-Fig-3e
  *** rNemo[tAb] upshift[WBMS] is unchanged by (rUbiq + rUbe1 + rUbe2c + rCiap1)
    *** cells: none
    *** source: 12867425-Fig-3e
  *** rNemo[tAb] upshift[WBMS] is unchanged by (rUbiq + rUbe1 + rUbe2l3 + rCiap1)
    *** cells: none
    *** source: 12867425-Fig-3e
  *** xNemo[tAb] upshift[WBMS] is unchanged itpo (xTak1 + xTab1)
    *** cells: HEK293T in BMS
    *** source: 19112497-Fig-5b
  *** xNemo[tAb] upshift[WBMS] is unchanged itpo xAsk1
    *** cells: HEK293T in BMS
    *** source: 19112497-Fig-5b
  *** xNemo[tAb] upshift[WBMS] is unchanged itpo xIkk2(mnr)"CA"
    *** cells: HEK293T in BMS
    *** source: 19112497-Fig-5b
  *** xNemo[tAb] upshift[WBMS] is unchanged itpo xMekk3
    *** cells: HEK293T in BMS
    *** source: 19112497-Fig-5b
  *** xNemo[tAb] upshift[WBMS] is unchanged itpo xTraf2
    *** cells: HEK293T in BMS
    *** source: 19112497-Fig-5b
  *** xNemo[tAb] upshift[WBMS] is unchanged itpo xTraf5
    *** cells: HEK293T in BMS
    *** source: 19112497-Fig-5b
  *** xNemo[tAb]IP phos[32Pi] is detectable
    *** cells: 70Z3<Nemo~null><xNemo> in BMS
    *** inhibited by: Wortmannin [addition]
    *** source: 16497931-Fig-S2a
  *** rNemo[tUbAb] ubiq[tUbAb] is increased by (rUbiq + rUbe1 + rUbe2d3 + rRbx1)
    *** cells: none
    *** inhibited by: rUbiq(dig)"no-lysines" [substitution]
    *** inhibited by: rUbiq(K48R) [substitution]
    *** source: 12867425-Fig-3i
  *** NFAT-reporter[Luc] is decreased itpo xFoxp3
    *** cells: mCD4TCs<Foxp3~fmut> in BMS "treated with anti-Cd3 + anti-Cd28 (24 hr)"
    *** source: 15790681-Fig-5a
  *** NFAT-reporter[Luc] is increased itao Foxp3 [fmut] 
    *** cells: mCD4TCs in BMS "treated with anti-Cd3 + anti-Cd28 (24 hr)"
    *** source: 15790681-Fig-5a
  *** NFAT-reporter[Luc] is increased itpo xNfatc2
    *** cells: HEK293T in BMS
    *** enhanced by: xNfatc2(mnr)"CA" [substitution]
    *** source: 15790681-Fig-3c
  *** NFAT-reporter[Luc] is increased itpo xNfatc2
    *** cells: HEK293T in BMS
    *** inhibited by: xFoxp3 [addition]
    *** source: 15790681-Fig-3c
  *** NFAT-reporter[Luc] is increased itpo xNfatc2(mnr)"CA"
    *** cells: HEK293T in BMS
    *** inhibited by: xFoxp3 [addition]
    *** source: 15790681-Fig-3c
  *** NFAT-reporter[Luc] is increased itpo xNfatc2(mnr)"CA"
    *** cells: JURKAT in BMS
    *** inhibited by: xFoxp3 [addition]
    *** source: 15790681-Fig-3d
  *** xNfat?[Gal4-DBD] Gal4-reporter[Luc] is decreased itpo xFoxp3
    *** cells: HEK293T in BMS
    *** source: 15790681-Fig-4d
  *** xNfat?[Gal4-DBD] Gal4-reporter[Luc] is decreased itpo xFoxp3
    *** cells: mCD4TCs in BMS "treated with anti-Cd3 + anti-Cd28 (24 hr)"
    *** source: 15790681-Fig-5c
  *** xNfat?[Gal4-DBD] Gal4-reporter[Luc] is decreased itpo xFoxp3
    *** cells: mCD4TCs<Foxp3~fmut> in BMS "treated with anti-Cd3 + anti-Cd28 (24 hr)"
    *** source: 15790681-Fig-5d
  *** xNfat?[Gal4-DBD] Gal4-reporter[Luc] is increased itao Foxp3 [fmut] 
    *** cells: mCD4TCs in BMS "treated with anti-Cd3 + anti-Cd28 (24 hr)"
    *** source: 15790681-Fig-5d
*** Nfatc1--
  *** Nfatc1[Ab] infraction(nuclear)[WB] is increased itpo xTraf6
    *** cells: RAW2647 in BMS
    *** inhibited by: xTraf6(C70A)"E3-mut" [substitution]
    *** source: 17135271-Fig-2e
  *** Nfatc1[Ab] infraction(nuclear)[WB] is increased itpo xTraf6
    *** cells: RAW2647 in BMS
    *** inhibited by: xTraf6(K124R) [substitution]
    *** unaffected by: xTraf6(K133R) [substitution]
    *** unaffected by: xTraf6(K142R) [substitution]
    *** source: 17135271-Fig-5c
  *** xNfatc2(mnr)"CA"[tAb] copptby[WB] xFoxp3[tAb] is detectable
    *** cells: HEK293T<xNfatc2(mnr)"CA"><xFoxp3> in BMS
    *** source: 15790681-Fig-4c
*** Nfkb--
  *** Nfkb-reporter[CAT] is decreased itpo xIkba
    *** cells: NTERA2<Rela~null><Ikba~null><xRela> in BMS
    *** source: 7878466-Fig-3a
  *** Nfkb-reporter[CAT] is increased itpo xTraf2
    *** cells: JURKATT in BMS
    *** source: 8910514-Fig-4a
  *** Nfkb-reporter[CAT] is increased itpo xTraf6
    *** cells: JURKATT in BMS
    *** source: 8910514-Fig-4a
  *** Nfkb-reporter[CAT] is unchanged itpo xTraf3
    *** cells: JURKATT in BMS
    *** source: 8910514-Fig-4a
  *** Nfkb-reporter[Luc] is decreased itpo xEgfR
    *** cells: HEK293<xTak1><xTab1><xTab2> in BMS
    *** reversed by: xTab1(T431A/S432A) [substitution]
    *** source: 19393267-Fig-6d
  *** Nfkb-reporter[Luc] is decreased itpo xFoxp3
    *** cells: mCD4TCs<Foxp3~fmut> in BMS "treated with anti-Cd3 + anti-Cd28 (24 hr)"
    *** source: 15790681-Fig-5b
  *** Nfkb-reporter[Luc] is decreased itpo xIkba(mnr)"phos-mut"
    *** cells: HELA in BMS
    *** unaffected by: xRasa1((1-445)/D157A)"Casp-resistant" [addition]
    *** unaffected by: xRasa1(456-1047)"Cterm" + xRasa1((1-445)/D157A)"Casp-resistant" [addition]
    *** source: 11847220-Fig-5b
  *** Nfkb-reporter[Luc] is decreased itpo xTak1(K34R)
    *** cells: HEK293 in BMLS
    *** source: 22069318-Fig-4a
  *** Nfkb-reporter[Luc] is decreased itpo xTak1(K34R)
    *** cells: HEK293<xIL1R1> in BMLS
    *** source: 22069318-Fig-5a
  *** Nfkb-reporter[Luc] is decreased itpo xTak1(K34R)
    *** cells: HEK293<xTLR4> in BMLS
    *** source: 22069318-Fig-6a
  *** Nfkb-reporter[Luc] is decreased itpo xTak1(K63W)
    *** cells: HEK293 in BMLS
    *** source: 22069318-Fig-4a
  *** Nfkb-reporter[Luc] is decreased itpo xTak1(K63W)
    *** cells: HEK293<xIL1R1> in BMLS
    *** source: 22069318-Fig-5a
  *** Nfkb-reporter[Luc] is decreased itpo xTak1(K63W)
    *** cells: HEK293<xTLR4> in BMLS
    *** source: 22069318-Fig-6a
  *** Nfkb-reporter[Luc] is decreased itpo xTak1(K63W)
    *** cells: HEPG2 in BMLS
    *** source: 22069318-Fig-7a
  *** Nfkb-reporter[Luc] is decreased itpo xTnfaip3
    *** cells: HEK293T in BMS "treated with Tnf for 8 hr"
    *** reqs: Rnf11 [RNAi]
    *** source: 19131965-Fig-5f
  *** Nfkb-reporter[Luc] is decreased itpo xTpl2(D270A)
    *** cells: JURKATT in BMS "treated with Tnf for 4 hr"
    *** source: 9950430-Fig-7c
  *** Nfkb-reporter[Luc] is detectable
    *** cells: HEK293<xCd40> in BMS
    *** inhibited by: xCd40(T254A) [substitution]
    *** source: 10433725-Fig-6a
  *** Nfkb-reporter[Luc] is detectable
    *** cells: HEK293T<xCd4><xTLR4> in BMS
    *** inhibited by: xMyd88(mnr)"DN" [addition]
    *** inhibited by: xIrak1(mnr)"DN" [addition]
    *** partially inhibited by: xRipk2(mnr)"DN" [addition]
    *** source: 11894097-Fig-5d
  *** Nfkb-reporter[Luc] is detectable
    *** cells: HEK293T<xNod1> in BMS
    *** unaffected by: xMyd88(mnr)"DN" [addition]
    *** unaffected by: xIrak1(mnr)"DN" [addition]
    *** inhibited by: xRipk2(mnr)"DN" [addition]
    *** source: 11894097-Fig-5d
  *** Nfkb-reporter[Luc] is detectable
    *** cells: HELA in BMLS
    *** partially reqs: Rsk2 [RNAi]
    *** source: 20385620-Fig-4d
  *** Nfkb-reporter[Luc] is detectable
    *** cells: mEFs in BMLS
    *** partially reqs: Rsk2 [RNAi]
    *** source: 20385620-Fig-4g
  *** Nfkb-reporter[Luc] is detectable
    *** cells: THP1 in BMS
    *** reqs: Ampka1 [RNAi]
    *** source: 22833096-Fig-3a
  *** Nfkb-reporter[Luc] is increased itao Foxp3 [fmut] 
    *** cells: mCD4TCs in BMS "treated with anti-Cd3 + anti-Cd28 (24 hr)"
    *** source: 15790681-Fig-5b
  *** Nfkb-reporter[Luc] is increased itpo (xTab1 + xTak1)
    *** cells: mEFs<Tak1~null> in BMS
    *** reqs: xTak1 [omission]
    *** inhibited by: xTak1(K63R) [substitution]
    *** partially inhibited by: xTak1(T178A) [substitution]
    *** partially inhibited by: xTak1(T184A) [substitution]
    *** inhibited by: xTak1(T178A/T184A) [substitution]
    *** unaffected by: xTak1(T178E) [substitution]
    *** unaffected by: xTak1(T184E) [substitution]
    *** enhanced by: xTak1(T178E/T184E) [substitution]
    *** source: 18617512-Fig-1b
  *** Nfkb-reporter[Luc] is increased itpo (xTak1 + xTab1)
    *** cells: HEK293 in BMS
    *** unaffected by: xTpl2(K167M) [addition]
    *** source: 15670770-Fig-3b
  *** Nfkb-reporter[Luc] is increased itpo (xTak1 + xTab1)
    *** cells: HEK293T in BMS
    *** inhibited by: xTnfaip3 [addition]
    *** source: 21220427-Fig-7c
  *** Nfkb-reporter[Luc] is increased itpo (xTak1 + xTab1)
    *** cells: HELA in BMS
    *** inhibited by: xTak1(T187A) [substitution]
    *** inhibited by: xTak1(K63W)"KD" [substitution]
    *** source: 15590691-Fig-1d
  *** Nfkb-reporter[Luc] is increased itpo (xTLR4 + xCd4)
    *** cells: HEK293 in BMS
    *** source: 15849198-Fig-2b
  *** Nfkb-reporter[Luc] is increased itpo xAkt1(mnr)"myr"
    *** cells: HELA in BMS
    *** inhibited by: xRasa1((1-445)/D157A)"Casp-resistant" [addition]
    *** source: 11847220-Fig-6
  *** Nfkb-reporter[Luc] is increased itpo xAmpka1
    *** cells: THP1 in BMS
    *** inhibited by: xAmpka1(D159A)"DN" [substitution]
    *** enhanced by: xAmpka1(T174D)"CA" [substitution]
    *** source: 22833096-Fig-1g
  *** Nfkb-reporter[Luc] is increased itpo xCd27
    *** cells: HEK293 in BMS
    *** inhibited by: xIkk2(K44A)"KD" [addition]
    *** source: 9520401-Fig-2a
  *** Nfkb-reporter[Luc] is increased itpo xCd40
    *** cells: HEK293 in BMS
    *** inhibited by: xIkk2(K44A)"KD" [addition]
    *** source: 9520401-Fig-2a
  *** Nfkb-reporter[Luc] is increased itpo xCd40
    *** cells: HEK293T in BMS
    *** enhanced by: xTraf2 [addition]
    *** source: 12370254-Fig-3b
  *** Nfkb-reporter[Luc] is increased itpo xCd40
    *** cells: HEK293T in BMS
    *** unaffected by: xTraf1 [addition]
    *** source: 12370254-Fig-3b
  *** Nfkb-reporter[Luc] is increased itpo xHras(G12V)
    *** cells: B16F10 in BMS
    *** source: 18003981-Fig-5b
  *** Nfkb-reporter[Luc] is increased itpo xIkk1
    *** cells: HEK293 in BMS
    *** partially inhibited by: xNfkb1(436-968)"delN" [addition]
    *** partially inhibited by: xNfkb1(mnr)"delNdelC5" [addition]
    *** partially inhibited by: xIkba [addition]
    *** inhibited by: xIkba(mnr)"delN" [addition]
    *** source: 10469655-Fig-8b
  *** Nfkb-reporter[Luc] is increased itpo xIkk1
    *** cells: HEK293 in BMS
    *** source: 17003035-Fig-4b
  *** Nfkb-reporter[Luc] is increased itpo xIkk1
    *** cells: HELA in BMS
    *** enhanced by: xIkk1(S176E) [substitution]
    *** inhibited by: xIkk1(K44A)"KD" [substitution]
    *** source: 9520446-Fig-7b
  *** Nfkb-reporter[Luc] is increased itpo xIkk2
    *** cells: HEK293 in BMS
    *** partially inhibited by: xNfkb1(436-968)"delN" [addition]
    *** partially inhibited by: xNfkb1(mnr)"delNdelC5" [addition]
    *** partially inhibited by: xIkba [addition]
    *** inhibited by: xIkba(mnr)"delN" [addition]
    *** source: 10469655-Fig-8b
  *** Nfkb-reporter[Luc] is increased itpo xIkk2
    *** cells: HEK293 in BMS
    *** source: 17003035-Fig-4b
  *** Nfkb-reporter[Luc] is increased itpo xIkk2
    *** cells: HEK293T in BMS
    *** inhibited by: xFoxp3 [addition]
    *** source: 15790681-Fig-2c
  *** Nfkb-reporter[Luc] is increased itpo xIkk2
    *** cells: HEK293T in BMS
    *** inhibited by: xIkk2(mnr)"KD" [substitution]
    *** source: 10783893-Fig-3a
  *** Nfkb-reporter[Luc] is increased itpo xIkk2
    *** cells: HEK293T in BMS
    *** unaffected by: xTbk1(K38M)"KD" [substitution]
    *** source: 10783893-Fig-3c
  *** Nfkb-reporter[Luc] is increased itpo xIkk2
    *** cells: HEK293T in BMS
    *** unaffected by: xTnfaip3 [addition]
    *** source: 21220427-Fig-7c
  *** Nfkb-reporter[Luc] is increased itpo xIrak1
    *** cells: HEK293T in BMS
    *** partially inhibited by: xTnfaip3 [addition]
    *** source: 21220427-Fig-7c
  *** Nfkb-reporter[Luc] is increased itpo xIrak2
    *** cells: HEK293T in BMS
    *** inhibited by: xTnfaip3 [addition]
    *** source: 21220427-Fig-7c
  *** Nfkb-reporter[Luc] is increased itpo xLtbR
    *** cells: HEK293 in BMS
    *** partially inhibited by: xIkk2(K44A)"KD" [addition]
    *** source: 9520401-Fig-2a
  *** Nfkb-reporter[Luc] is increased itpo xMekk1
    *** cells: HEK293 in BMS
    *** inhibited by: xIkk1(K44A)"KD" [addition]
    *** source: 9520401-Fig-4
  *** Nfkb-reporter[Luc] is increased itpo xMekk1
    *** cells: HEK293 in BMS
    *** inhibited by: xIkk2(K44A)"KD" [addition]
    *** source: 9520401-Fig-4
  *** Nfkb-reporter[Luc] is increased itpo xMekk1
    *** cells: HEK293 in BMS
    *** partially inhibited by: xNik(K429A/K430A)"KD" [addition]
    *** source: 9520401-Fig-4
  *** Nfkb-reporter[Luc] is increased itpo xMekk1
    *** cells: HEK293T in BMS
    *** inhibited by: xFoxp3 [addition]
    *** source: 15790681-Fig-2a
  *** Nfkb-reporter[Luc] is increased itpo xMekk1
    *** cells: HELA in BMS
    *** source: 11847220-Fig-5a
  *** Nfkb-reporter[Luc] is increased itpo xMekk1
    *** cells: HELA in BMS
    *** unaffected by: xRasa1((1-445)/D157A)"Casp-resistant" [addition]
    *** source: 11847220-Fig-6
  *** Nfkb-reporter[Luc] is increased itpo xMyd88
    *** cells: HEK293T in BMS
    *** inhibited by: xTnfaip3 [addition]
    *** source: 21220427-Fig-7c
  *** Nfkb-reporter[Luc] is increased itpo xNik
    *** cells: HEK293 in BMS
    *** enhanced by: xIkk1 [addition]
    *** unaffected by: xIkk1(S176A) [addition]
    *** source: 9520446-Fig-5a
  *** Nfkb-reporter[Luc] is increased itpo xNik
    *** cells: HEK293 in BMS
    *** inhibited by: xIkk2(K44A)"KD" [addition]
    *** partially inhibited by: xIkk2(K44A)"KD" [addition]
    *** source: 9520401-Fig-2b
  *** Nfkb-reporter[Luc] is increased itpo xNik
    *** cells: HEK293 in BMS
    *** source: 17003035-Fig-4b
  *** Nfkb-reporter[Luc] is increased itpo xNik
    *** cells: JURKATT in BMS
    *** source: 9950430-Fig-3c
  *** Nfkb-reporter[Luc] is increased itpo xNik
    *** cells: JURKATT in BMS
    *** unaffected by: xNfkb1(435-880)"3'NN" [addition]
    *** source: 9950430-Fig-3c
  *** Nfkb-reporter[Luc] is increased itpo xPkca
    *** cells: HEK293T in BMS
    *** unaffected by: xTbk1(K38M)"KD" [addition]
    *** source: 10783893-Fig-3g
  *** Nfkb-reporter[Luc] is increased itpo xPkce
    *** cells: HEK293T in BMS
    *** inhibited by: xTbk1(K38M)"KD" [addition]
    *** source: 10783893-Fig-3f
  *** Nfkb-reporter[Luc] is increased itpo xPkcq
    *** cells: HEK293T in BMS
    *** inhibited by: xFoxp3 [addition]
    *** source: 15790681-Fig-2a
  *** Nfkb-reporter[Luc] is increased itpo xPkcq
    *** cells: HEK293T in BMS
    *** unaffected by: xTbk1(K38M)"KD" [addition]
    *** source: 10783893-Fig-3f
  *** Nfkb-reporter[Luc] is increased itpo xRela
    *** cells: HEK293T in BMS
    *** inhibited by: xFoxp3 [addition]
    *** source: 15790681-Fig-2c
  *** Nfkb-reporter[Luc] is increased itpo xRela
    *** cells: HEK293T in BMS
    *** unaffected by: xTnfaip3 [addition]
    *** source: 21220427-Fig-7c
  *** Nfkb-reporter[Luc] is increased itpo xTab1
    *** cells: HEK293T<xTak1> in BMS
    *** unaffected by: xTak1(K34R) [substitution]
    *** unaffected by: xTak1(K52R/K54R) [substitution]
    *** unaffected by: xTak1(K58R) [substitution]
    *** inhibited by: xTak1(K63R) [substitution]
    *** unaffected by: xTak1(K72R) [substitution]
    *** unaffected by: xTak1(K91R) [substitution]
    *** unaffected by: xTak1(K150R) [substitution]
    *** inhibited by: xTak1(K158R) [substitution]
    *** unaffected by: xTak1(K172R) [substitution]
    *** unaffected by: xTak1(K190R) [substitution]
    *** unaffected by: xTak1(K209R) [substitution]
    *** unaffected by: xTak1(K227R) [substitution]
    *** unaffected by: xTak1(K253R) [substitution]
    *** unaffected by: xTak1(K257R) [substitution]
    *** unaffected by: xTak1(K269R) [substitution]
    *** unaffected by: xTak1(K282R) [substitution]
    *** source: 20038579-Fig-3e
  *** Nfkb-reporter[Luc] is increased itpo xTab2
    *** cells: HEK293T in BMS
    *** inhibited by: xIkba(mnr)"KD" [addition]
    *** source: 20194509-Fig-4b
  *** Nfkb-reporter[Luc] is increased itpo xTab2
    *** cells: HEK293T in BMS
    *** inhibited by: xIkba(S32A/S36A) [addition]
    *** source: 20194509-Fig-4a
  *** Nfkb-reporter[Luc] is increased itpo xTak1
    *** cells: mEFs<Tak1~null> in BMS "treated with Tgfb1 for 6 hr"
    *** inhibited by: xTak1(K158R) [substitution]
    *** unaffected by: xTak1(K34R) [substitution]
    *** unaffected by: xTak1(K209R) [substitution]
    *** source: 20837137-Fig-4a
  *** Nfkb-reporter[Luc] is increased itpo xTak1
    *** cells: mEFs<Tak1~null><xTab1> in BMS
    *** inhibited by: xTak1(T178A) [substitution]
    *** unaffected by: xTak1(T184A) [substitution]
    *** inhibited by: xTak1(T178A/T184A) [substitution]
    *** unaffected by: xTak1(T178E/T184E) [substitution]
    *** source: 18617512-Fig-3c
  *** Nfkb-reporter[Luc] is increased itpo xTbk1
    *** cells: HEK293T in BMS
    *** inhibited by: xTbk1(K38M)"KD" [substitution]
    *** source: 10783893-Fig-3a
  *** Nfkb-reporter[Luc] is increased itpo xTbk1
    *** cells: HEK293T in BMS
    *** unaffected by: xTbk1(K38M)"KD" [substitution]
    *** source: 10783893-Fig-3c
  *** Nfkb-reporter[Luc] is increased itpo xTbk1
    *** cells: mEFs in BMS
    *** partially reqs: Ikk1 [KO]
    *** partially reqs: Ikk2 [KO]
    *** source: 10783893-Fig-3d
  *** Nfkb-reporter[Luc] is increased itpo xTnfRsf8
    *** cells: HEK293 in BMS
    *** inhibited by: xIkk2(K44A)"KD" [addition]
    *** source: 9520401-Fig-2a
  *** Nfkb-reporter[Luc] is increased itpo xTpl2
    *** cells: HEK293 in BMS
    *** inhibited by: xTak1(K63W) [addition]
    *** source: 15670770-Fig-3b
  *** Nfkb-reporter[Luc] is increased itpo xTpl2
    *** cells: HEK293T in BMS
    *** inhibited by: xTpl2(K167R)"KD" [substitution]
    *** inhibited by: xTpl2(T290A) [substitution]
    *** inhibited by: xTpl2(T290D) [substitution]
    *** inhibited by: xTpl2(T290E) [substitution]
    *** source: 15466476-Fig-5
  *** Nfkb-reporter[Luc] is increased itpo xTpl2
    *** cells: JURKATT in BMS
    *** inhibited by: xNfkb1(435-880)"3'NN" [addition]
    *** source: 9950430-Fig-3c
  *** Nfkb-reporter[Luc] is increased itpo xTpl2
    *** cells: JURKATT in BMS
    *** inhibited by: xTpl2(S270A)"KD" [substitution]
    *** inhibited by: xTpl2(1-398)"delC" [substitution]
    *** source: 9950430-Fig-3c
  *** Nfkb-reporter[Luc] is increased itpo xTraf1
    *** cells: HEK293T<xCd40><xTraf2> in BMS
    *** reqs: xCd40 [omission]
    *** reqs: xTraf2 [omission]
    *** source: 12370254-Fig-3b
  *** Nfkb-reporter[Luc] is increased itpo xTraf2
    *** cells: HEK293 in BMS
    *** inhibited by: xIkk2(K44A)"KD" [addition]
    *** source: 9520401-Fig-2b
  *** Nfkb-reporter[Luc] is increased itpo xTraf2
    *** cells: HEK293 in BMS
    *** inhibited by: xTpl2(K167M) [addition]
    *** source: 15670770-Fig-2e
  *** Nfkb-reporter[Luc] is increased itpo xTraf2
    *** cells: HEK293T in BMLS
    *** source: 12370254-Fig-5b
  *** Nfkb-reporter[Luc] is increased itpo xTraf2
    *** cells: mEFs<Tak1~null><xTak1> in BMS
    *** inhibited by: xTak1(K158R) [substitution]
    *** source: 20038579-Fig-5g
  *** Nfkb-reporter[Luc] is increased itpo xTraf2
    *** cells: mEFs<Tak1~null><xTak1> in BMS
    *** inhibited by: xTak1(K158R) [substitution]
    *** source: 20038579-Fig-5h
  *** Nfkb-reporter[Luc] is increased itpo xTraf5
    *** cells: HEK293 in BMS
    *** inhibited by: xIkk2(K44A)"KD" [addition]
    *** source: 9520401-Fig-2b
  *** Nfkb-reporter[Luc] is increased itpo xTraf6
    *** cells: HEK293 in BMS
    *** enhanced by: xZnf274 [addition]
    *** source: 14960584-Fig-8a
  *** Nfkb-reporter[Luc] is increased itpo xTraf6
    *** cells: HEK293 in BMS
    *** inhibited by: xIkk2(K44A)"KD" [addition]
    *** partially inhibited by: xIkk2(K44A)"KD" [addition]
    *** source: 9520401-Fig-2b
  *** Nfkb-reporter[Luc] is increased itpo xTraf6
    *** cells: HEK293 in BMS
    *** inhibited by: xTpl2(K167M) [addition]
    *** source: 15670770-Fig-2e
  *** Nfkb-reporter[Luc] is increased itpo xTraf6
    *** cells: HEK293T in BMS
    *** inhibited by: xTnfaip3 [addition]
    *** source: 21220427-Fig-7c
  *** Nfkb-reporter[Luc] is increased itpo xTrif
    *** cells: HEK293 in BMS
    *** inhibited by: xTraf6(mnr)"6CT" [addition]
    *** source: 14530355-Fig-3a
  *** Nfkb-reporter[Luc] is increased itpo xTrif
    *** cells: HEK293 in BMS
    *** partially inhibited by: xTrif(E88A/E252A/E303A) [substitution]
    *** partially inhibited by: xTrif(mnr)"delC" [substitution]
    *** inhibited by: xTrif(E88A/E252A/E303A/mnr)"delC" [substitution]
    *** source: 14530355-Fig-2c
  *** Nfkb-reporter[Luc] is increased itpo xTrif
    *** cells: HEK293 in BMS
    *** unaffected by: xTrif(E88A) [substitution]
    *** partially inhibited by: xTrif(E88A/E252A) [substitution]
    *** partially inhibited by: xTrif(E88A/E252A/E303A) [substitution]
    *** source: 14530355-Fig-2b
  *** Nfkb-reporter[Luc] is unchanged itpo xBtk
    *** cells: HEK293 in BMS
    *** source: 15849198-Fig-2b
  *** Nfkb-reporter[Luc] is unchanged itpo xBtk
    *** cells: HEK293<xTLR4> in BMS
    *** source: 15849198-Fig-2b
  *** Nfkb-reporter[Luc] is unchanged itpo xRasa1((1-445)/D157A)"Casp-resistant"
    *** cells: HELA in BMS
    *** source: 11847220-Fig-5a
  *** Nfkb-reporter[Luc] is unchanged itpo xRasa1(456-1047)"Cterm"
    *** cells: HELA in BMS
    *** source: 11847220-Fig-5a
  *** Nfkb-reporter[Luc] is unchanged itpo xTak1(K34R)
    *** cells: HEPG2 in BMLS
    *** source: 22069318-Fig-6a
  *** Nfkb-reporter[Luc] is unchanged itpo xTraf1
    *** cells: HEK293T in BMS
    *** source: 12370254-Fig-3b
  *** Nfkb-reporter[Luc] is unchanged itpo xTraf6(mnr)"DN"
    *** cells: HEPG2 in BMLS
    *** source: 22069318-Fig-6a
  *** Nfkb[RE] oligo-binding[EMSA] is detectable
    *** cells: 70Z3<Nemo~null><xNemo> in BMS "treated with Etoposide for 2 hr"
    *** inhibited by: Wortmannin [addition]
    *** inhibited by: Caffeine [addition]
    *** source: 16497931-Fig-S4e
  *** Nfkb[RE] oligo-binding[EMSA] is detectable
    *** cells: 70Z3<Nemo~null><xNemo> in BMS "treated with Etoposide for 2 hr"
    *** partially inhibited by: xNemo(ubiq/S85A) [substitution]
    *** source: 16497931-Fig-S4e
  *** Nfkb[RE] reporter[Luc] is increased itpo (xTak1 + xTab1)
    *** cells: HEK293 in BMS
    *** reqs: xTak1 [omission]
    *** inhibited by: xTak1(S192A) [substitution]
    *** inhibited by: xTak1(S192D) [substitution]
    *** inhibited by: xTak1(S192E) [substitution]
    *** source: 10702308-Fig-4b
*** Nfkb1--
  *** xNfkb1(1-433)[Ab] copptby[WB] xTnip2[tAb] is undetectable
    *** cells: HEK293<xTnip2><xNfkb1(1-433)> in BMS
    *** source: 15169888-Fig-2a
  *** rNfkb1(433-968)[32P] phos[32P-ATP] is increased by Nemo[Ab]IP
    *** cells: none
    *** IPfrom: mBMMs in BMS "treated with Lps for 15 min"
    *** inhibited by: rNfkb1(433-968/S921A/S923A/S927A) [substitution]
    *** source: 15199157-Fig-9a
  *** xNfkb1(mnr)"delGRR"[tAb]IP prot-stability[35S-pulse-chase] is decreased itpo xTpl2
    *** cells: NIH3T3<xNfkb1> in BMS
    *** reversed by: MG132 [pretreatment]
    *** source: 9950430-Fig-6g
  *** xNfkb1(mnr)"delGRR"[tAb]IP prot-stability[35S-pulse-chase] is decreased itpo xTpl2
    *** cells: NIH3T3<xNfkb1> in BMS
    *** reversed by: xTpl2(D270A)"KD" [substitution]
    *** source: 9950430-Fig-6d
  *** rNfkb1[32P] phos[32P-ATP] is unchanged by rTbk1
    *** cells: none
    *** source: 14560022-Fig-6a
  *** Nfkb1[Ab] copptby[WB] Tnip2[Ab] is detectable
    *** cells: HELAS3 in BMS
    *** source: 15169888-Fig-1c
  *** Nfkb1[Ab] copptby[WB] Tnip2[Ab] is detectable
    *** cells: mBMMs in BMS
    *** source: 15169888-Fig-4a
  *** xNfkb1[Ab] copptby[WB] xTnip2[tAb] is detectable
    *** cells: HEK293<xTnip2><xNfkb1> in BMS
    *** source: 15169888-Fig-2a
  *** Nfkb1[Ab] oligo-binding[ELISA] is increased itpo xIkke
    *** cells: HEK293 in BMS
    *** source: 16199137-Fig-5c
  *** Nfkb1[Ab] oligo-binding[EMSA] is increased itpo xPin1
    *** cells: HEK293T in BMS
    *** source: 14690596-Fig-2c
  *** Nfkb1[Ab] oligo-binding[EMSA] is increased itpo xTbk1
    *** cells: HEK293 in BMS "nuclear-extracts"
    *** inhibited by: xTbk1(K38A) [substitution]
    *** source: 10581243-Fig-2a
  *** Nfkb1[Ab] oligo-binding[EMSA] is increased itpo xTradd
    *** cells: HEK293 in BMS
    *** source: 7758105-Fig-5a
  *** Nfkb1[Ab] oligo-binding[EMSA] is increased itpo xTraf2
    *** cells: HEK293 in BMS "nuclear-extracts"
    *** source: 7544915-Fig-1
  *** Nfkb1[Ab] prot-exp[WB] is detectable
    *** cells: HEK293 in BMS
    *** does not req: Tnip2 [RNAi]
    *** source: 15169888-Fig-7b
  *** Nfkb1[Ab] prot-exp[WB] is detectable
    *** cells: HEK293 in BMS
    *** does not req: Tnip2 [RNAi]
    *** source: 15169888-Fig-7c
  *** Nfkb1[Ab] prot-exp[WB] is detectable
    *** cells: HELAS3 in BMS
    *** does not req: Tnip2 [RNAi]
    *** source: 15169888-Fig-7a
  *** Nfkb1[Ab] prot-exp[WB] is detectable
    *** cells: HELAS3 in BMS
    *** does not req: Tnip2 [RNAi]
    *** source: 15169888-Fig-7c
  *** xNfkb1[Ab] snaggedby[WB] rTnip2[GST] is detectable
    *** cells: HEK293<xNfkb1> in BMS
    *** partially inhibited by: xNfkb1(1-892) [substitution]
    *** inhibited by: xNfkb1(1-801) [substitution]
    *** inhibited by: xNfkb1(mnr)"delDD" [substitution]
    *** inhibited by: xNfkb1(L841D) [substitution]
    *** partially inhibited by: xNfkb1(del(497-538)) [substitution]
    *** source: 15169888-Fig-5b
  *** xNfkb1[Ab] snaggedby[WB] rTnip2[GST] is detectable
    *** cells: HEK293<xNfkb1> in BMS
    *** unaffected by: rTnip2(1-250) [substitution]
    *** inhibited by: rTnip2(1-89) [substitution]
    *** inhibited by: rTnip2(1-107) [substitution]
    *** inhibited by: rTnip2(1-129) [substitution]
    *** inhibited by: rTnip2(1-193) [substitution]
    *** inhibited by: rTnip2(90-250) [substitution]
    *** inhibited by: rTnip2(130-250) [substitution]
    *** inhibited by: rTnip2(194-250) [substitution]
    *** source: 15169888-Fig-6c
  *** xNfkb1[Ab] snaggedby[WB] rTnip2[GST] is detectable
    *** cells: HEK293<xNfkb1> in BMS
    *** unaffected by: rTnip2(1-250) [substitution]
    *** inhibited by: rTnip2(251-429) [substitution]
    *** source: 15169888-Fig-6b
  *** xNfkb1[Ab] snaggedby[WB] rTnip2[GST] is increased itpo xTpl2
    *** cells: HEK293<xNfkb1> in BMS
    *** source: 15169888-Fig-3c
  *** xNfkb1[Ab]IP prot-stability[35S-pulse-chase] is decreased itpo xIkk2
    *** cells: NIH3T3<xNfkb1> in BMS
    *** reversed by: xNfkb1(S927A) [substitution]
    *** reversed by: xNfkb1(S927T) [substitution]
    *** source: 11297557-Fig-6a
  *** xNfkb1[Ab]IP prot-stability[35S-pulse-chase] is decreased itpo xIkk2
    *** cells: NIH3T3<xNfkb1> in BMS
    *** reversed by: xNfkb1(S927A) [substitution]
    *** source: 11297557-Fig-3a
  *** xNfkb1[Ab]IP prot-stability[35S-pulse-chase] is decreased itpo xIkk2
    *** cells: NIH3T3<xNfkb1> in BMS
    *** unaffected by: xNfkb1(S921A) [substitution]
    *** unaffected by: xNfkb1(S923A) [substitution]
    *** reversed by: xNfkb1(S927A) [substitution]
    *** partially reversed by: xNfkb1(S932A) [substitution]
    *** source: 11297557-Fig-3b
  *** xNfkb1[tAb] locatedin(nucleus)[IHC] is detectable
    *** cells: NIH3T3<xNfkb1><xTpl2> in BMS
    *** comment: xNfkb1 tag is on Nterm so cannot say whether this is p105 or p50
    *** inhibited by: xTpl2(S270D)"KD" [substitution]
    *** source: 9950430-Fig-4a
  *** xNfkb1[tAb] prot-exp[WB] is decreased itpo xTpl2
    *** cells: NIH3T3<xNfkb1> in BMS
    *** source: 9950430-Fig-6g
  *** xNfkb1[tAb] prot-exp[WB] is unchanged itpo xTpl2
    *** cells: HEK293<xNfkb1> in BMS
    *** source: 15169888-Fig-3c
  *** xNfkb1[tAb] ubiq[UbAb] is detectable
    *** cells: HEK293<xNfkb1><xIkk2><xBtrc> in BMS "treated with ALLN"
    *** inhibited by: xNfkb1(S921A/S923A/S927A) [substitution]
    *** source: 11158290-Fig-4
  *** xNfkb1[tAb]IP phos[WBMS-PPase] is increased itpo xTpl2
    *** cells: NIH3T3<xNfkb1> in BMS
    *** inhibited by: xTpl2(D270A)"KD" [substitution]
    *** source: 9950430-Fig-7d
  *** xNfkb1[tAb]IP prot-stability[35S-pulse-chase] is decreased itpo xTpl2
    *** cells: NIH3T3<xNfkb1> in BMS
    *** source: 9950430-Fig-6b
  *** xNfkb1[tAb]IP prot-stability[CHX-WB] is decreased itpo xBtrc
    *** cells: HEK293<xNfkb1><xIkk2> in BMS
    *** comment: the amount of xNfkb1{p50} does not change as xNfkb1 decreases
    *** reversed by: xNfkb1(S921A/S923A/S927A) [substitution]
    *** source: 11158290-Fig-5a
  *** xNfkb1[tAb]IP prot-stability[CHX-WB] is decreased itpo xBtrc
    *** cells: HEK293<xNfkb1><xIkk2> in BMS
    *** unaffected by: xNfkb1(18-968/S921A)"M1" [substitution]
    *** partially reversed by: xNfkb1(18-968/S923A)"M2" [substitution]
    *** reversed by: xNfkb1(18-968/S927A)"M3" [substitution]
    *** unaffected by: xNfkb1(18-968/S932A)"M7" [substitution]
    *** reversed by: xNfkb1(18-968/S927T)"M6" [substitution]
    *** partially reversed by: xNfkb1(18-968/S921A/S923A)"M4" [substitution]
    *** reversed by: xNfkb1(18-968/S923A/S927A)"M8" [substitution]
    *** reversed by: xNfkb1(18-968/S921A/S923A/S927A)"AAA" [substitution]
    *** comment: Nfkb1{p50} is detectable only in samples sensitive to xBtrc
    *** source: 11158290-Fig-5b
  *** Nfkb1{p50}[Ab] copptby[WB] Tpl2[Ab] is detectable
    *** cells: HELA in BMS
    *** source: 9950430-Fig-3a
  *** Nfkb1{p50}[Ab] prot-exp[WB] is detectable
    *** cells: HEK293 in BMS
    *** does not req: Tnip2 [RNAi]
    *** source: 15169888-Fig-7c
  *** Nfkb1{p50}[Ab] prot-exp[WB] is detectable
    *** cells: HELAS3 in BMS
    *** does not req: Tnip2 [RNAi]
    *** source: 15169888-Fig-7c
  *** xNfkb1{p50}[tAb] locatedin(nucleus)[IHC] is detectable
    *** cells: NIH3T3<xNfkb1><xTpl2(S270D)> in BMS
    *** source: 9950430-Fig-5
  *** xNfkb1{p50}[tAb] locatedin(nucleus)[IHC] is detectable
    *** cells: NIH3T3<xNfkb1><xTpl2><xNfkb1(mnr)"delGRR"> in BMS
    *** comment: xNfkb1{p50} relocates to cyto when xTpl2(S270D) is substituted
    *** source: 9950430-Fig-5
  *** xNfkb1{p50}[tAb] prot-exp[WB] is increased itpo xTpl2
    *** cells: NIH3T3<xNfkb1> in BMS
    *** source: 9950430-Fig-6g
  *** xNfkb1{p50}[tAb]IP prot-exp[WB] is increased itpo xIkk2
    *** cells: HEK293<xNfkb1> in BMS
    *** inhibited by: xBtrc [addition]
    *** unaffected by: CHX [addition]
    *** source: 11158290-Fig-5a
  *** xNfkb1{p50}[tAb]IP prot-exp[WB] is increased itpo xIkk2
    *** cells: HEK293<xNfkb1> in BMS
    *** inhibited by: xIkk2(mnr)"KD" [substitution]
    *** partially inhibited by: xNfkb1(1-850)"delC5" [substitution]
    *** partially inhibited by: xNfkb1(18-809)"delC6" [substitution]
    *** source: 11158290-Fig-6b
  *** xNfkb1{p50}[tAb]IP prot-exp[WB] is increased itpo xIkk2
    *** cells: HEK293<xNfkb1> in BMS
    *** inhibited by: xNfkb1(S921A/S923A/S927A) [substitution]
    *** source: 11158290-Fig-6b
  *** xNfkb1{p50}[tAb]IP prot-exp[WB] is increased itpo xTpl2
    *** cells: HEK293<xNfkb1> in BMS
    *** partially inhibited by: xTpl2(mnr)"KD" [substitution]
    *** source: 11158290-Fig-6b
  *** xNfkb1{p50}[tAb]IP prot-exp[WB] is increased itpo xTpl2
    *** cells: HEK293<xNfkb1> in BMS
    *** unaffected by: xNfkb1(S921A/S923A/S927A) [substitution]
    *** source: 11158290-Fig-6b
*** Nfkb2--
  *** Nfkb2[Ab] cleavage[WB] is detectable
    *** cells: mLNBCs in BMS
    *** reqs: Ikk1 [KO]
    *** source: 11520989-Fig-2d
  *** Nfkb2[Ab] cleavage[WB] is detectable
    *** cells: mSpBCs in BMS
    *** reqs: Ikk1 [KO]
    *** source: 11520989-Fig-2d
  *** Nfkb2[Ab] cleavage[WB] is increased itao Nemo [KO]
    *** cells: mEFs in BMS
    *** source: 12387745-Fig-6c
  *** xNfkb2[Ab] cleavage[WB] is increased itpo xNik
    *** cells: HEK293 in BMS
    *** partially inhibited by: xTraf3 [addition]
    *** source: 15084608-Fig-3a,3b
  *** Nfkb2[Ab] cleavage[WB] is increased itpo xNik
    *** cells: HEK293 in BMS
    *** source: 17003035-Fig-4a
  *** Nfkb2[Ab] cleavage[WB] is increased itpo xNik
    *** cells: HEK293<xCd40> in BMS
    *** source: 12374738-Fig-1a
  *** xNfkb2[Ab] cleavage[WB] is increased itpo xNik
    *** cells: mEFs in BMS
    *** reqs: Ikk1 [KO]
    *** does not req: Ikk2 [KO]
    *** source: 11520989-Fig-4a
  *** Nfkb2[Ab] cleavage[WB] is unchanged itpo xIkk1
    *** cells: HEK293 in BMS
    *** source: 17003035-Fig-4a
  *** Nfkb2[Ab] cleavage[WB] is unchanged itpo xIkk2
    *** cells: HEK293 in BMS
    *** source: 17003035-Fig-4a
  *** Nfkb2[Ab] cleavage[WB] is unchanged itpo xIkke
    *** cells: HEK293 in BMS
    *** source: 17003035-Fig-4a
  *** Nfkb2[Ab] cleavage[WB] is unchanged itpo xTbk1
    *** cells: HEK293 in BMS
    *** source: 17003035-Fig-4a
  *** Nfkb2[Ab] copptby[WB] Ikba[Ab] is detectable
    *** cells: mSpBCs in BMS
    *** comment: coppt Nfkb2 is 52 kD not 100kD
    *** source: 12374738-Fig-6a
  *** Nfkb2[Ab] copptby[WB] Nfkb1[Ab] is detectable
    *** cells: HELAS3 in BMS
    *** source: 15169888-Fig-1c
  *** Nfkb2[Ab] copptby[WB] Tnip2[Ab] is undetectable
    *** cells: HELAS3 in BMS
    *** source: 15169888-Fig-1c
  *** Nfkb2[Ab] copptby[WB] Tpl2[Ab] is undetectable
    *** cells: HELAS3 in BMS
    *** source: 15169888-Fig-1c
  *** Nfkb2[Ab] oligo-binding[EMSA] is detectable
    *** cells: mSpBCs in BMS
    *** reqs: Ikk1 [KO]
    *** source: 11520989-Fig-2e
  *** Nfkb2[Ab] oligo-binding[EMSA] is unchanged itpo xTraf2
    *** cells: HEK293 in BMS "nuclear-extracts"
    *** source: 7544915-Fig-1
  *** xNfkb2[Ab]IP cleavage[WB] is increased itpo xNik
    *** cells: HEK293 in BMS
    *** inhibited by: xNfkb2(S866A/S870A) [substitution]
    *** inhibited by: xNfkb2(S866D/S870D) [substitution]
    *** inhibited by: xNfkb2(S872A) [substitution]
    *** unaffected by: xNfkb2(S872D) [substitution]
    *** source: 15140882-Fig-2b,3b,5
  *** xNfkb2[Ab]IP cleavage[WB] is increased itpo xNik
    *** cells: HEK293<xIkk1> in BMS
    *** inhibited by: xNfkb2(S866A/S870A) [substitution]
    *** inhibited by: xNik(mnr)"KD" [substitution]
    *** unaffected by: xIkk1(mnr)"KD" [substitution]
    *** source: 15140882-Fig-1a,1b,2a
  *** xNfkb2[Ab]IP ubiq[UbAb] is increased itpo xNik
    *** cells: HEK293 in BMS
    *** inhibited by: xNfkb2(S866A/S870A) [substitution]
    *** inhibited by: xNfkb2(S99A/S108A/S115A/S123A/S872A) [substitution]
    *** source: 15140882-Fig-6b
  *** xNfkb2[tAb]IP prot-stability[CHX-WB] is unchanged itpo xBtrc
    *** cells: HEK293<xNfkb2><xIkk2> in BMS
    *** comment: the amount of xNfkb2{p52} is also unchanged
    *** source: 11158290-Fig-5b
  *** xNfkb2[tAb]IP ubiq[tUbAb] is increased itpo xNik
    *** cells: HEK293<xUbiq> in BMS
    *** enhanced by: MG132 [addition]
    *** source: 12374738-Fig-2c
  *** xNfkb2{p52}[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xIkke
    *** cells: HEK293 in BMS
    *** inhibited by: xIkke(K38A)"KD" [substitution]
    *** source: 17003035-Fig-4d
  *** xNfkb2{p52}[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xIkke
    *** cells: mEFs in BMS
    *** reqs: Rela [KO]
    *** source: 17003035-Fig-6b
  *** xNfkb2{p52}[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xRela
    *** cells: HEK293 in BMS
    *** enhanced by: xIkke [addition]
    *** source: 17003035-Fig-6a
  *** xNfkb2{p52}[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xRela
    *** cells: HEK293 in BMS
    *** source: 17003035-Fig-6a
  *** xNfkb2{p52}[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xIkk1
    *** cells: HEK293 in BMS
    *** source: 17003035-Fig-4d
  *** xNfkb2{p52}[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xIkk2
    *** cells: HEK293 in BMS
    *** source: 17003035-Fig-4d
  *** xNfkb2{p52}[tAb]IP prot-exp[WB] is increased itpo xIkk2
    *** cells: HEK293<xNfkb2> in BMS
    *** inhibited by: xIkk2(mnr)"KD" [substitution]
    *** source: 11158290-Fig-6b
  *** xNfkb2{p52}[tAb]IP prot-exp[WB] is increased itpo xTpl2
    *** cells: HEK293<xNfkb2> in BMS
    *** partially inhibited by: xTpl2(mnr)"KD" [substitution]
    *** source: 11158290-Fig-6b
  *** rNfkb2{p100}[GST] phos[32P-ATP] is unchanged by xIkke[Ab]IP
    *** cells: none
    *** IPfrom: HEK293<xIkke> in BMS
    *** source: 17003035-Fig-4c
  *** xNgfR[125I] boundby[Xlink] rBdnf[125I] is detectable
    *** cells: COS<xNgfR> in BMS
    *** source: 1710174-Fig-1
  *** xNgfR[125I] boundby[Xlink] rNtf3[125I] is detectable
    *** cells: COS<xNgfR> in BMS
    *** source: 1710174-Fig-1
  *** xNgfR[Ab] copptby[WB] xEgfR[Ab] is undetectable
    *** cells: HEK293<xNgfR><xEgfR> in BMS
    *** source: 9927421-Fig-1b
  *** xNgfR[Ab] copptby[WB] xTraf6[tAb] is detectable
    *** cells: HEK293<xNgfR><xTraf6> in BMS
    *** source: 14960584-Fig-11
  *** xNgfR[Ab] copptby[WB] xTraf6[tAb] is detectable
    *** cells: HEK293<xNgfR><xTraf6><xZnf274> in BMS
    *** source: 14960584-Fig-11
  *** xNgfR[Ab] copptby[WB] xTrka[Ab] is detectable
    *** cells: HEK293<xNgfR><xTrka> in BMS
    *** source: 9927421-Fig-1a
  *** xNgfR[Ab] copptby[WB] xTrkb[Ab] is detectable
    *** cells: HEK293<xNgfR><xTrkb> in BMS
    *** source: 9927421-Fig-1a
  *** xNgfR[Ab] copptby[WB] xTrkc[Ab] is detectable
    *** cells: HEK293<xNgfR><xTrkc> in BMS
    *** source: 9927421-Fig-1a
*** Nik--
  *** Nik-gene mRNA[RTPCR] is increased itao Traf2 [KO]
    *** cells: mEFs in BMS
    *** source: 18997792-Fig-S1d
  *** Nik-gene mRNA[RTPCR] is increased itao Traf3 [KO]
    *** cells: mEFs in BMS
    *** source: 18997792-Fig-S1d
  *** xNik(K429A/K430A)[tAb] phos[WBMS-PPase] is increased itpo (xTak1 + xTab1)
    *** cells: HEK293 in BMS
    *** source: 10094049-Fig-3a
  *** xNik(K429A/K430A)[tAb] phos[WBMS-PPase] is increased itpo (xTak1 + xTab1)
    *** cells: HEK293 in BMS
    *** source: 10094049-Fig-3c
  *** xNik(K429A/K430A)[tAb]IP IVKA(auto)[32P-ATP] is increased itpo (xTak1 + xTab1)
    *** cells: HEK293 in BMS
    *** source: 10094049-Fig-3b
  *** xNik(K429A/K430A/K549A/T552A/T559A)[tAb] phos[WBMS] is increased itpo (xTak1 + xTab1)
    *** cells: HEK293 in BMS
    *** source: 10094049-Fig-3c
  *** xNik[Ab] copptby[WB] xIkk1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: xTak1 [addition]
    *** source: 10094049-Fig-4b
  *** Nik[Ab] prot-exp[WB] is decreased itpo xCiap1
    *** cells: HEK293T in BMS
    *** source: 18997792-Fig-S3c
  *** Nik[Ab] prot-exp[WB] is decreased itpo xCiap2
    *** cells: HEK293T in BMS
    *** source: 18997792-Fig-S3c
  *** Nik[Ab] prot-exp[WB] is decreased itpo xTraf2
    *** cells: HEK293T in BMS
    *** reversed by: xTraf2(mnr)"delN" [substitution]
    *** source: 18997792-Fig-S3c
  *** Nik[Ab] prot-exp[WB] is decreased itpo xTraf3
    *** cells: HEK293T in BMS
    *** source: 18997792-Fig-S3b
  *** Nik[Ab] prot-exp[WB] is increased itao Traf2 [KO]
    *** cells: mEFs in BMS
    *** source: 18997792-Fig-3b
  *** Nik[Ab] prot-exp[WB] is increased itao Traf3 [KO]
    *** cells: mEFs in BMS
    *** source: 18997792-Fig-3b
  *** xNik[Ab]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: HEK293 in BMS
    *** source: 15084608-Fig-3c
  *** xNik[Ab]IP IVKA(Ikk1)[32P-ATP] is detectable
    *** cells: HEK293 in BMS
    *** source: 15084608-Fig-3c
  *** xNik[tAb] cleavage[WB] is increased itpo xCasp8
    *** cells: HEK293 in BMS
    *** inhibited by: xCrmA [addition]
    *** source: 10753878-Fig-5a
  *** xNik[tAb] copptby[WB] xAkt1[tAb] is undetectable
    *** cells: HEK293T<xNik><xAkt1> in BMS
    *** source: 12138205-Fig-2a
  *** xNik[tAb] copptby[WB] xNfkb2[tAb] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: xNfkb2(S866A/S870A) [substitution]
    *** source: 15140882-Fig-2b
  *** xNik[tAb] copptby[WB] xNfkb2[tAb] is detectable
    *** cells: HEK293<xIkk1> in BMS
    *** unaffected by: xNik(mnr)"KD" [substitution]
    *** unaffected by: xIkk1(mnr)"KD" [substitution]
    *** source: 15140882-Fig-1b
  *** xNik[tAb] copptby[WB] xNod1[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 10329646(D)
  *** xNik[tAb] copptby[WB] xPeli3[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12874243-Fig-5b
  *** xNik[tAb] prot-exp[WB] is decreased itpo xTraf2
    *** cells: HEK293T<xNik> in BMS
    *** reversed by: MG132 [pretreatment]
    *** source: 18997792-Fig-S3d
  *** xNik[tAb] prot-exp[WB] is decreased itpo xTraf2
    *** cells: HEK293T<xNik> in BMS
    *** reversed by: xTraf2(mnr)"delN" [substitution]
    *** source: 18997792-Fig-3c
  *** xNik[tAb] prot-exp[WB] is decreased itpo xTraf2
    *** cells: HEK293T<xNik> in BMS
    *** reversed by: xTraf2(mnr)"delN" [substitution]
    *** source: 18997792-Fig-S3d
  *** xNik[tAb] prot-exp[WB] is decreased itpo xTraf3
    *** cells: HEK293T in BMS
    *** unaffected by: xTraf3(mnr)"delN" [substitution]
    *** source: 18997792-Fig-3c
  *** xNik[tAb]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xNik(K429A/K430A) [substitution]
    *** source: 10094049-Fig-3b
  *** xNik[tAb]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xNik(K429A/K430A)"KD" [substitution]
    *** source: 9520446-Fig-1a
*** Nkirass--
  *** Nkirass[Ab] copptby[WB] xIkba[tAb] is undetectable
    *** cells: JURKAT<Pten~null> in BMS
    *** source: 15024091-Fig-1c
  *** Nkirass[Ab] copptby[WB] xIkbb[tAb] is detectable
    *** cells: JURKAT<Pten~null> in BMS
    *** source: 15024091-Fig-1c
  *** rNlk[Ab] boundby[WB] rTab2[GST] is detectable
    *** cells: none
    *** source: 20194509-Fig-1b
  *** xNlk[Ab] copptby[WB] xCtnnb1[Ab] is detectable
    *** cells: HEK293<xCtnnb1><xTcf7l2><xNlk> in BMS
    *** source: 10391247-Fig-5a
  *** xNlk[tAb] copptby[WB] xTab2[tAb] is detectable
    *** cells: HEK293T<xNlk><xTab2> in BMS
    *** inhibited by: xNlk(1-293)"N" [substitution]
    *** inhibited by: xNlk(293-515)"C" [substitution]
    *** unaffected by: xNlk(del(11-105))"delN" [substitution]
    *** inhibited by: xNlk(1-421)"delC" [substitution]
    *** source: 20194509-Fig-1d
  *** xNlk[tAb] copptby[WB] xTab2[tAb] is detectable
    *** cells: HEK293T<xNlk><xTab2> in BMS
    *** inhibited by: xTab2(del(292-417))"delM" [substitution]
    *** source: 20194509-Fig-1d
  *** xNlk[tAb] copptby[WB] xTab2[tAb] is detectable
    *** cells: HEK293T<xNlk><xTab2> in BMS
    *** source: 20194509-Fig-1a
  *** xNlk[tAb] copptby[WB] xTab2[tAb] is detectable
    *** cells: HEK293T<xNlk><xTab2> in BMS
    *** unaffected by: xTab2(178-693)"C1" [substitution]
    *** unaffected by: xTab2(292-693)"C2" [substitution]
    *** inhibited by: xTab2(417-693)"C3" [substitution]
    *** inhibited by: xTab2(477-693)"C4" [substitution]
    *** source: 20194509-Fig-1f
  *** xNlk[tAb] copptby[WB] xTab2[tAb] is detectable
    *** cells: HEK293T<xNlk><xTab2><xTak1(K63W)> in BMS
    *** does not req: xTak1(K63W) [omission]
    *** source: 20194509-Fig-1d
  *** xNlk[tAb] IVKA(auto)[32P-ATP] is increased itpo xTab2
    *** cells: HEK293T<xNlk> in BMS
    *** unaffected by: xTab2(del(292-417))"delM" [substitution]
    *** enhanced by: xTak1 [addition]
    *** source: 20194509-Fig-5a
  *** xNlk[tAb] IVKA(auto)[32P-ATP] is unchanged itpo xTak1
    *** cells: HEK293T<xNlk> in BMS
    *** source: 20194509-Fig-5a
  *** xNlk[tAb] IVKA(Lef1)[32P-ATP] is increased itpo xTab2
    *** cells: HEK293T<xNlk> in BMS
    *** inhibited by: xTab2(del(292-417))"delM" [substitution]
    *** source: 20194509-Fig-5b
  *** xNlk[tAb]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: HEK293<xNlk> in BMS
    *** inhibited by: xNlk(K155M) [substitution]
    *** inhibited by: xNlk(C425Y) [substitution]
    *** source: 10391247-Fig-3b
  *** xNlk[tAb]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: HEK293<xNlk> in BMS
    *** inhibited by: xNlk(K155M) [substitution]
    *** source: 10391247-Fig-3a
  *** xNlk[tAb]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: HEK293<xNlk><xTcf7l2> in BMS
    *** inhibited by: xNlk(K155M) [substitution]
    *** source: 10391247-Fig-4c
  *** xNlk[tAb]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: HEK293<xNlk><xTcf7l2> in BMS
    *** unaffected by: xTak1 + xTab1 [addition]
    *** source: 10391247-Fig-4c
  *** xNlk[tAb]IP IVKA(auto)[32P-ATP] is increased itpo (xTak1 + xTab1)
    *** cells: HEK293<xNlk> in BMS
    *** reqs: xTab1 [omission]
    *** source: 10391247-Fig-3a
  *** xNlk[tAb]IP IVKA(Lef1)[32P-ATP] is detectable
    *** cells: HEK293<xNlk><xTcf7l2> in BMS
    *** source: 10391247-Fig-4d
  *** xNlrp2[tAb] copptby[WB] xIpaf[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 15107016(D)
  *** xNod1[tAb] copptby[WB] xIpaf[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 15107016(D)
  *** xNod1[tAb] copptby[WB] xRipk2[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 10329646(D)
  *** xNod1[tAb] copptby[WB] xRipk2[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 10224040-Fig-2b
  *** xNod1[tAb] oligomerization[2TagPpt] is detectable
    *** cells: HEK293 in BMS
    *** source: 10329646(D)
  *** xNod1[tAb] oligomerization[2TagPpt] is detectable
    *** cells: HEK293T in BMS
    *** source: 10880512-Fig-2b
  *** xNod2[tAb] copptby[WB] xCasp1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 15107016(D)
  *** xNod2[tAb] copptby[WB] xIpaf[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 15107016(D)
  *** xNod2[tAb] copptby[WB] xRipk2[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 11087742-Fig-6a
*** Nos2a--
  *** Nos2a-gene promo-reporter[Luc] is detectable
    *** cells: CHO<xEgfR> in BMLS
    *** partially reqs: Stat3 [RNAi]
    *** source: 15950906-Fig-5g
  *** Nos2a-gene promo-reporter[Luc] is detectable
    *** cells: RAW2647<xPparg> in BMS "treated with Ifng + Lps for 24 hr"
    *** inhibited by: Rosiglitazone [addition]
    *** inhibited by: 15HETE [addition]
    *** inhibited by: 13HODE [addition]
    *** source: 10432118-Fig-2e
  *** Nos2a-gene promo-reporter[Luc] is detectable
    *** cells: RAW2647<xPparg> in BMS "treated with Lps for 24 hr"
    *** unaffected by: xAlox15 [addition]
    *** enhanced by: LinoleicAcid [addition]
    *** inhibited by: Rosiglitazone [addition]
    *** source: 10432118-Fig-2e
  *** Nos2a-gene promo-reporter[Luc] is detectable
    *** cells: RAW2647<xPparg><xAlox15> in BMS "treated with Lps for 24 hr"
    *** inhibited by: LinoleicAcid [addition]
    *** source: 10432118-Fig-2e
  *** Nos2a[Ab] prot-exp[WB] is detectable
    *** cells: CHO<xEgfR> in BMLS
    *** partially reqs: Stat3 [RNAi]
    *** source: 15950906-Fig-5h
*** Nos3--
  *** Nos3[phosAb] phos(S1179)[phosAb] is detectable
    *** cells: bAECs in BMLS
    *** unaffected by: Wortmannin [addition]
    *** does not req: Akt1 [RNAi]
    *** does not req: Rac1 [RNAi]
    *** source: 17519230(D)
  *** xNova1[Ab] copptby[WB] Atm[Ab] is undetectable
    *** cells: IMR90<xNova1> in BMS
    *** source: 15314656-Fig-4a
*** Nphp1--
  *** xNphp1[tAb] copptby[WB] Bcar1[Ab] is detectable
    *** cells: COS7 in BMS
    *** source: 10739664-Fig-5
  *** xNphp1[tAb] copptby[WB] Bcar1[Ab] is detectable
    *** cells: MDCK in BMS
    *** source: 10739664-Fig-6a
  *** Nprl2[Ab] copptby[WB] Pdpk1[Ab] is detectable
    *** cells: MCF7 in BMS
    *** source: 18616680-Fig-1c
  *** xNprl2[tAb] copptby[WB] xPdpk1[tAb] is detectable
    *** cells: HEK293T<xNprl2><xPdpk1> in BMS
    *** partially inhibited by: xPdpk1(1-459)"dPH" [substitution]
    *** enhanced by: xPdpk1(1-196)"dC196" [substitution]
    *** unaffected by: xPdpk1(1-242)"dC242" [substitution]
    *** enhanced by: xPdpk1(1-342)"dC342" [substitution]
    *** source: 18616680-Fig-2d
  *** xNprl2[tAb] copptby[WB] xPdpk1[tAb] is detectable
    *** cells: HEK293T<xNprl2><xPdpk1> in BMS
    *** source: 18616680-Fig-1b
  *** rNr3c1[35S] boundby[WB] rJun[GST] is detectable
    *** cells: none
    *** enhanced by: rJun(105-334) [substitution]
    *** source: 14522952-Fig-1c
  *** rNr3c1[35S] boundby[WB] rStat3[GST] is detectable
    *** cells: none
    *** partially inhibited by: rStat3(134-319) [substitution]
    *** enhanced by: rStat3(320-495) [substitution]
    *** partially inhibited by: rStat3(496-688) [substitution]
    *** partially inhibited by: rStat3(584-688) [substitution]
    *** source: 14522952-Fig-1c
  *** rNras GDP-dissociation[3H-GDP] is increased by rRasGrf1
    *** cells: none
    *** source: 8524240-Fig-2b
  *** rNras GDP-dissociation[3H-GDP] is unchanged by rRalGds
    *** cells: none
    *** source: 8094051-Fig-5
  *** rNras GDP-dissociation[3H-GDP] is unchanged by rRap1Gds1
    *** cells: none
    *** source: 11948427-Fig-1d
  *** rNras GDP-dissociation[3H-GDP] is unchanged by rRapGef1
    *** cells: none
    *** source: 8524240-Fig-2a
*** Nras--
  *** xNras(G12V)[tAb]IP IVKA(Mek1,Erk2,MBP)[32P-ATP] is increased itpo (xMras(H81L)"CA" + xShoc2)
    *** cells: HEK293T<xRaf1> in BMS
    *** reqs: both [omissions]
    *** source: 16630891-Fig-6c
  *** xNras(Q81L)"CA"[tAb] copptby[WB] xShoc2[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** unaffected by: xRaf1 [addition]
    *** source: 16630891-Fig-1d
  *** Nras[Ab] copptby[WB] Pkcd[Ab] is undetectable
    *** cells: C3H10T12 in BMLS "PM2 fraction"
    *** source: 11358964-Fig-2f
  *** Nras[Ab] copptby[WB] Pkce[Ab] is detectable
    *** cells: C3H10T12 in BMLS "PM2 fraction"
    *** source: 11358964-Fig-2f
  *** Nras[Ab] copptby[WB] Raf1[Ab] is undetectable
    *** cells: C3H10T12 in BMLS "PM2 fraction"
    *** source: 11358964-Fig-2f
  *** Nras[Ab] GTP-association[BDPD] is increased itpo (xTnk2 + xCdc42(G12V)"CA")
    *** cells: HEK293<xRasGrf1> in BMLS
    *** source: 10882715-Fig-6
  *** Nras[Ab] GTP-association[BDPD] is increased itpo xTnk2(L543F)"CA"
    *** cells: HEK293<xRasGrf1> in BMLS
    *** source: 10882715-Fig-6
  *** Nras[Ab] GTP-association[BDPD] is unchanged itpo xRasGrf1
    *** cells: HEK293 in BMLS
    *** source: 10882715-Fig-6
  *** xNras[tAb] copptby[WB] xShoc2[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** unaffected by: xRaf1 [addition]
    *** source: 16630891-Fig-1d
  *** xNras[tAb]IP GTP-association[TLC] is increased itpo xRasGrp2
    *** cells: COS in BMS
    *** source: 10918068-Fig-4a
  *** xNras[tAb]IP GTP-association[TLC] is increased itpo xRasGrp2
    *** cells: COS in BMS
    *** source: 10918068-Fig-4b
  *** xNras[tAb]IP GTP-association[TLC] is unchanged itpo xRasGrf1
    *** cells: NIH3T3 in BMLS
    *** source: 9430727-Fig-1
  *** Ntf3[125I] receptor-binding[RIA] is detectable
    *** cells: NIH3T3<xTrkc> in BMS
    *** source: 1375038-Fig-1c
  *** Numb[Ab] copptby[WB] Cdh1[Ab] is detectable
    *** cells: MDCK2 in BMS
    *** inhibited by: Src(mnr)"vSrc" [addition]
    *** unaffected by: Pervanadate [addition]
    *** enhanced by: PP2 [addition]
    *** source: 19609305-Fig-1a
  *** Numb[Ab] copptby[WB] xCdh1[tAb] is detectable
    *** cells: MDCK2<xCdh1> in BMS
    *** inhibited by: xCdh1(Y753A/Y754A/Y755A) [substitution]
    *** unaffected by: xCdh1(Y753F/Y754F/Y755F) [substitution]
    *** source: 19609305-Fig-1e
*** Nup62--
  *** Nup62[Ab] copptby[WB] Smad2[Ab] is detectable
    *** cells: COS1 in BMS
    *** source: 12191473-Fig-1e
*** Nup153--
  *** xNup153(1156-1476)[tAb] copptby[WB] xSmad2[tAb] is detectable
    *** cells: COS1 in BMS
    *** comment: xNup153(1156-1476) dissociates from IP when rFoxh1 is added
    *** source: 12191473-Fig-5a
  *** xNup153(1156-1476)[tAb] snaggedby[WB] rSmad3(146-425)"LMH2"[GST] is detectable
    *** cells: COS1 in BMS
    *** inhibited by: rSmad3((146-425)/V356R) [substitution]
    *** unaffected by: rSmad3((146-425)/P403H) [substitution]
    *** inhibited by: rSmad3((146-425)/W406A) [substitution]
    *** source: 12917407-Fig-7a
  *** rNup153[Ab] boundby[WB] xErk2[tAb]IP is detectable
    *** cells: none
    *** IPfrom: COS7<xErk2> in BMLS
    *** enhanced by: rErk2(S246A/S248A) [substitution]
    *** inhibited by: rErk2(S246E/S248E) [substitution]
    *** source: 18760948-Fig-6b
  *** Nup153[Ab] copptby[WB] Smad2[Ab] is detectable
    *** cells: COS1 in BMS
    *** source: 12191473-Fig-1e
*** Nup214--
  *** xNup214(1600-2091)[tAb] copptby[WB] xSmad2[tAb] is detectable
    *** cells: COS1 in BMS
    *** comment: xNup214(1600-2091) dissociates from IP when rFoxh1 is added
    *** source: 12191473-Fig-5a
  *** xNup214(1600-2091)[tAb] snaggedby[WB] rSmad2(185-467)"LMH2"[GST] is detectable
    *** cells: COS1 in BMS
    *** inhibited by: rSmad2((185-467)/W448A) [substitution]
    *** inhibited by: rSmad2((185-467)/C380R/L382R) [substitution]
    *** inhibited by: rSmad2((185-467)/L382R/K383A) [substitution]
    *** partially inhibited by: rSmad2((185-467)/V398R) [substitution]
    *** unaffected by: rSmad2((185-467)/P445H) [substitution]
    *** source: 12191473-Fig-2e
  *** xNup214(1600-2091)[tAb] snaggedby[WB] rSmad2(186-467)"LMH2"[GST] is detectable
    *** cells: COS1 in BMS
    *** inhibited by: rSmad2(1-185)"MH1" [substitution]
    *** source: 12917407-Fig-6b
  *** xNup214(1600-2091)[tAb] snaggedby[WB] rSmad3(146-425)"LMH2"[GST] is detectable
    *** cells: COS1 in BMS
    *** inhibited by: rSmad3(1-145)"MH1" [substitution]
    *** source: 12917407-Fig-6b
  *** xNup214(1600-2091)[tAb] snaggedby[WB] rSmad3(146-425)"LMH2"[GST] is detectable
    *** cells: COS1 in BMS
    *** partially inhibited by: rSmad3((146-425)/V356R) [substitution]
    *** unaffected by: rSmad3((146-425)/P403H) [substitution]
    *** inhibited by: rSmad3((146-425)/W406A) [substitution]
    *** source: 12917407-Fig-7a
  *** xNup214(1600-2091)[tAb] snaggedby[WB] rSmad4(146-552)"LMH2"[GST] is detectable
    *** cells: COS1 in BMS
    *** inhibited by: rSmad4(1-145)"MH1" [substitution]
    *** source: 12917407-Fig-6b
  *** xNup214(1864-2091)[tAb] copptby[WB] xSmad2[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 12191473-Fig-1b
  *** Nup214[Ab] copptby[WB] Smad2[Ab] is detectable
    *** cells: COS1 in BMS
    *** source: 12191473-Fig-1e
*** Oxsr1--
  *** xOxsr1[tAb] copptby[WB] xWnk1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 16263722(D)
  *** xOxsr1[tAb] copptby[WB] xWnk4[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 16263722(D)
*** P38--
  *** xP38?[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xArhGef7
    *** cells: NIH3T3 in BMS
    *** inhibited by: xArhGef7(W43K)"SH3-mut" [substitution]
    *** inhibited by: xArhGef7(L238R/L239S) [substitution]
    *** source: 11309380-Fig-3a
  *** xP38?[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xArhGef7
    *** cells: NIH3T3 in BMS
    *** inhibited by: xPak1(K299R)"KD" [addition]
    *** source: 11309380-Fig-4a
  *** xP38?[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xArhGef7
    *** cells: NIH3T3 in BMS
    *** source: 11309380-Fig-1a
  *** xP38?[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xAsk1
    *** cells: HEK293 in BMS
    *** inhibited by: xIkbkap [addition]
    *** source: 12058026-Fig-4e
  *** xP38?[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xAxin1
    *** cells: HEK293T<xP38?> in BMS
    *** partially inhibited by: xAxin1(1-600)"C1" [substitution]
    *** source: 10575011-Fig-1a
  *** xP38?[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xMekk1
    *** cells: HEK293T<xP38?> in BMS
    *** source: 10521462-Fig-5c
  *** xP38?[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xMekk1
    *** cells: NotReported in BMS
    *** source: 8643568-Fig-7
  *** xP38?[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xMkk6
    *** cells: HEK293T<xP38?> in BMS
    *** source: 9890973-Fig-4b
  *** xP38?[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xPak1
    *** cells: HEK293 in BMS
    *** source: 8668187-Fig-1c
  *** xP38?[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xPak2
    *** cells: HEK293 in BMS
    *** source: 8668187-Fig-1c
  *** xP38?[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xRac2(G12V)"CA"
    *** cells: HEK293 in BMS
    *** source: 8668187-Fig-1c
  *** xP38?[tAb]IP IVKA(Atf2)[32P-ATP] is unchanged itpo xHras(G12V)"CA"
    *** cells: HEK293 in BMS
    *** source: 8668187-Fig-1c
  *** xP38?[tAb]IP IVKA(Atf2)[32P-ATP] is unchanged itpo xMap4k4
    *** cells: HEK293T<xP38?> in BMS
    *** source: 9890973-Fig-4b
  *** xP38?[tAb]IP IVKA(Atf2)[32P-ATP] is unchanged itpo xTnik
    *** cells: HEK293T<xP38?> in BMS
    *** source: 10521462-Fig-5c
  *** xP38?[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMekk1
    *** cells: HEK293 in BMS
    *** source: 8668187-Fig-2a
  *** xP38?[tAb]IP IVKA(Jun)[32P-ATP] is increased itpo xMlk3
    *** cells: COS in BMS
    *** source: 8702571-Fig-1d
  *** xP38?[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xCdc42(Q61L)"CA"
    *** cells: COS1 in BMS
    *** source: 7499279-Fig-5
  *** xP38?[tAb]IP Yphos[pYAb] is increased itpo xMlk3
    *** cells: HELA in BMS
    *** source: 9003778-Fig-3a
  *** rP38a IVKA(Atf2)[32P-ATP] is unchanged by rMkk7
    *** cells: none
    *** source: 9384583-Fig-1b
*** P38a--
  *** rP38a[32P] phos[32P-ATP] is unchanged by rTaok1(1-416)"CA"
    *** cells: none
    *** source: 9786855-Fig-4b
  *** rP38a[35S] boundby[WB] rUbe2i[GST] is detectable
    *** cells: none
    *** source: 15210726-Fig-1b
  *** xP38a[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: CCL39<xP38a> in BMS
    *** unaffected by: xDusp6(C293S) [addition]
    *** source: 9927426-Fig-2a
  *** P38a[Ab]IP IVKA(Atf2)[32P-ATP] is decreased itpo xDusp1
    *** cells: NotReported in BMS
    *** source: 7535770-Fig-10
  *** P38a[Ab]IP IVKA(Atf2)[32P-ATP] is decreased itpo xDusp2
    *** cells: NotReported in BMS
    *** reversed by: xDusp2(C257S)"catalytically-inactive-mut" [substitution]
    *** source: 7535770-Fig-10
  *** xP38a[Ab]IP IVKA(Atf2)[32P-ATP] is unchanged itpo xMek1
    *** cells: COS1 in BMS
    *** source: 7839144-Fig-5
  *** xP38a[phosAb] phos(TPY)[phosAb] is increased itpo xRgl2(mnr)"CAAX"
    *** cells: NIH3T3<xInsR> in BMLS
    *** source: 12110590-Fig-5d
  *** xP38a[tAb] snaggedby[WB] rSin1[GST] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: rSin1(del(321-356)) [substitution]
    *** inhibited by: rSin1(1-467) [substitution]
    *** unaffected by: rSin1(468-522) [substitution]
    *** source: 17054722-Fig-3b
  *** xP38a[tAb]IP IVKA(Atf2)(sitenr)[phosAb] is increased itpo xRin1(Q78L)
    *** cells: PC6 in BMLS
    *** source: 16157584-Fig-4b
  *** xP38a[tAb]IP IVKA(Atf2)(T71)[phosAb] is increased itpo xRgl2(mnr)"CAAX"
    *** cells: NIH3T3<xInsR> in BMLS
    *** source: 12110590-Fig-5e
  *** xP38a[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xAsk1
    *** cells: COS7 in BMS
    *** source: 8974401-Fig-2a
  *** xP38a[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xMekk1
    *** cells: COS1 in BMS
    *** source: 9808624-Fig-1e
  *** xP38a[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xMekk1
    *** cells: NIH3T3 in BMLS
    *** source: 9006902-Fig-2b
  *** xP38a[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xMekk3
    *** cells: NIH3T3 in BMLS
    *** source: 9006902-Fig-2b
  *** xP38a[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xMekk4
    *** cells: COS7 in BMS
    *** source: 9305639-Fig-7a
  *** xP38a[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xMekk4
    *** cells: HELA in BMS
    *** source: 9305639-Fig-7a
  *** xP38a[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xRipk1
    *** cells: HEK293 in BMS
    *** unaffected by: xRipk1(D138N)"KD" [substitution]
    *** source: 9712898-Fig-3a
  *** xP38a[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xRipk1
    *** cells: mEFs<Ripk1~null> in BMS
    *** unaffected by: xRipk1(K45A)"KD" [substitution]
    *** source: 12776182-Fig-3d
  *** xP38a[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xTak1(mnr)"CA"
    *** cells: COS7 in BMS
    *** source: 8663074-Fig-4a
  *** xP38a[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xTraf2
    *** cells: HEK293 in BMS
    *** source: 9712898-Fig-5b
  *** xP38a[tAb]IP IVKA(Atf2)[32P-ATP] is unchanged itpo xMek1(del(32-51)/S218E/S222D)
    *** cells: COS1 in BMS
    *** source: 8622669-Fig-2b
  *** xP38a[tAb]IP IVKA(Atf2)[32P-ATP] is unchanged itpo xMkk7
    *** cells: COS7 in BMS
    *** source: 9384583-Fig-1a
  *** xP38a[tAb]IP IVKA(Atf2)[32P-ATP] is unchanged itpo xMkk7
    *** cells: HELA in BMS
    *** source: 9535930-Fig-3b
  *** xP38a[tAb]IP IVKA(Atf2)[32P-ATP] is unchanged itpo xMlk3
    *** cells: COS7 in BMS
    *** source: 8910292(D)
  *** xP38a[tAb]IP IVKA(Atf2)[32P-ATP] is unchanged itpo xRaf1(del(66-303))"CA"
    *** cells: NIH3T3 in BMLS
    *** source: 9006902-Fig-2b
  *** xP38a[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xIrak1
    *** cells: HEK293 in BMS
    *** source: 10346818-Fig-1b
  *** xP38a[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xTraf6
    *** cells: HEK293 in BMS
    *** source: 10346818-Fig-1b,2c
  *** xP38a[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xDusp5
    *** cells: COS1<xJnk1> in BMS "stimulated with anisomycin"
    *** source: 15713638-Fig-2c
  *** xP38a[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xMek1(S218E/S222E)"CA"
    *** cells: NIH3T3 in BMS
    *** source: 10669751-Fig-5a
  *** xP38a[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xMek5(mnr)"CA"
    *** cells: NIH3T3 in BMS
    *** source: 10669751-Fig-5a
  *** xP38a[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xMekk1
    *** cells: NIH3T3 in BMS
    *** source: 10669751-Fig-5a
  *** xP38a[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xTpl2
    *** cells: NIH3T3 in BMS
    *** source: 10669751-Fig-5a
  *** xP38a[tAb]IP phos(TGY)[phosAb] is unchanged itpo xHras(Q61L)"CA"
    *** cells: NIH3T3 in BMLS
    *** source: 10446149-Fig-5c
  *** xP38a[tAb]IP phos(TGY)[phosAb] is unchanged itpo xMras(Q71L)"CA"
    *** cells: NIH3T3 in BMLS
    *** source: 10446149-Fig-5c
  *** xP38a[XFP] locatedin(nucleus-cytoplasm)[IHC] is detectable
    *** cells: NIH3T3<xErk2> in BMS
    *** source: 15713638-Fig-9a
  *** xP38a[XFP] locatedin(nucleus)[IHC] is unchanged itpo xDusp5
    *** cells: NIH3T3<xP38a> in BMS
    *** source: 15713638-Fig-9b
*** P38d--
  *** xP38d[tAb]IP IVKA(Atf2)(sitenr)[phosAb] is unchanged itpo xRin1(Q78L)
    *** cells: PC6 in BMLS
    *** source: 16157584-Fig-4b
  *** xP38d[tAb]IP IVKA(Atf2)[32P-ATP] is increased itpo xTpl2
    *** cells: NIH3T3 in BMS
    *** source: 10669751-Fig-5b
  *** xP38d[tAb]IP IVKA(Atf2)[32P-ATP] is unchanged itpo xMek1(S218E/S222E)"CA"
    *** cells: NIH3T3 in BMS
    *** source: 10669751-Fig-5b
  *** xP38d[tAb]IP IVKA(Atf2)[32P-ATP] is unchanged itpo xMek5(mnr)"CA"
    *** cells: NIH3T3 in BMS
    *** source: 10669751-Fig-5b
  *** xP38d[tAb]IP IVKA(Atf2)[32P-ATP] is unchanged itpo xMekk1
    *** cells: NIH3T3 in BMS
    *** source: 10669751-Fig-5b
  *** rP38g IVKA(MBP)[32P-ATP] is unchanged by rMkk7
    *** cells: none
    *** source: 9384583-Fig-1b
*** P38g--
  *** xP38g[tAb]IP IVKA(Atf2)(sitenr)[phosAb] is unchanged itpo xRin1(Q78L)
    *** cells: PC6 in BMLS
    *** source: 16157584-Fig-4b
  *** xP38g[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xTpl2
    *** cells: NIH3T3 in BMS
    *** source: 10669751-Fig-5b
  *** xP38g[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xMek1(S218E/S222E)"CA"
    *** cells: NIH3T3 in BMS
    *** source: 10669751-Fig-5b
  *** xP38g[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xMek5(mnr)"CA"
    *** cells: NIH3T3 in BMS
    *** source: 10669751-Fig-5b
  *** xP38g[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xMekk1
    *** cells: NIH3T3 in BMS
    *** source: 10669751-Fig-5b
  *** xP38g[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xMkk7
    *** cells: COS7 in BMS
    *** source: 9384583-Fig-1a
*** P38s--
  *** P38s[Ab] copptby[WB] Mekk1[Ab] is undetectable
    *** cells: HEK293 in BMS
    *** unaffected by: Nocodazole [addition]
    *** unaffected by: Sorbitol (30 min) [stim]
    *** source: 10969079-Fig-8a
  *** P38s[Ab] locatedin(nucleus-cytoplasm)[IHC] is detectable
    *** cells: CCL39 in BMS
    *** unaffected by: xDusp6(C293S) [addition]
    *** source: 9927426-Fig-2a
  *** P38s[Ab] snaggedby[WB] rPea15[GST] is detectable
    *** cells: CHO in BMS
    *** source: 11702783-Fig-5d
  *** P38s[Ab]IP IVKA(Atf2)[32P-ATP] is increased itpo xMekk2
    *** cells: HEK293 in BMS
    *** source: 10347227-Fig-6b
  *** P38s[Ab]IP IVKA(Atf2)[32P-ATP] is increased itpo xMekk3
    *** cells: HEK293 in BMS
    *** source: 10347227-Fig-6b
  *** P38s[Ab]IP IVKA(Atf2)[32P-ATP] is increased itpo xMekk3
    *** cells: HEK293EBNA in BMS
    *** inhibited by: xMekk3(S526A) [substitution]
    *** inhibited by: xMekk3(T530A) [substitution]
    *** source: 16407301-Fig-3b
  *** P38s[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xCdc42(Q61L)
    *** cells: CHO in BMLS
    *** source: 9111305-Fig-7b
  *** P38s[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xHras(Q61L)
    *** cells: CHO in BMLS
    *** source: 9111305-Fig-7b
  *** P38s[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xRac1(Q61L)
    *** cells: CHO in BMLS
    *** source: 9111305-Fig-7b
  *** P38s[Ab]IP IVKA(Jun)[32P-ATP] is increased itpo xRhoa(Q63L)
    *** cells: CHO in BMLS
    *** source: 9111305-Fig-7b
  *** P38s[Ab]IP IVKA(MBP)[32P-ATP] is increased itpo xMlk3
    *** cells: COS1 in BMS
    *** source: 9003778-Fig-5
  *** P38s[phosAb] phos(TGY)[phosAb] is decreased itao Traf6 [KO]
    *** cells: mEFs in BMS
    *** source: 18758450-Fig-5a
  *** P38s[phosAb] phos(TGY)[phosAb] is detectable
    *** cells: HEPG2 in BMLS "plated on collagen"
    *** partially inhibited by: Gefitinib [cotreatment]
    *** partially inhibited by: PD325901 [cotreatment]
    *** partially inhibited by: BMS345541 [cotreatment]
    *** partially inhibited by: PHA818637 [cotreatment]
    *** partially inhibited by: ZSTK474 [cotreatment]
    *** source: 19953085-Fig-S1
  *** P38s[phosAb] phos(TGY)[phosAb] is detectable
    *** cells: PC3U<xTgfbR1> in BMS
    *** inhibited by: xTgfbR1(E161A) [substitution]
    *** source: 21629263-Fig-2a
  *** P38s[phosAb] phos(TGY)[phosAb] is increased itpo (xTak1 + xTab1)
    *** cells: HELA in BMS
    *** inhibited by: xTak1(T187A) [substitution]
    *** inhibited by: xTak1(K63W)"KD" [substitution]
    *** source: 15590691-Fig-1c
  *** P38s[phosAb] phos(TGY)[phosAb] is increased itpo xGadd45b
    *** cells: mSPOvaBlasts<Cd4~pos> in BMS "resting"
    *** source: 1175814-Fig-4a
  *** P38s[phosAb] phos(TGY)[phosAb] is increased itpo xHras(Q61L)"CA"
    *** cells: COS in BMS
    *** inhibited by: SB203580 [addition]
    *** source: 15632082-Fig-2a
  *** P38s[phosAb] phos(TGY)[phosAb] is increased itpo xHras(Q61L)"CA"
    *** cells: mEFs<Jnk1~null><Jnk2~null> in BMLS
    *** source: 19647037-Fig-3a
  *** P38s[phosAb] phos(TGY)[phosAb] is increased itpo xHras(Q61L)"CA"
    *** cells: PC6 in BMLS
    *** inhibited by: SB203580 [addition]
    *** source: 15632082-Fig-2a
  *** P38s[phosAb] phos(TGY)[phosAb] is increased itpo xHras(Q61L)"CA"
    *** cells: PC6 in BMLS
    *** source: 15632082-Fig-1c
  *** P38s[phosAb] phos(TGY)[phosAb] is increased itpo xMekk1
    *** cells: HEK293 in BMS
    *** unaffected by: xRgl3 [addition]
    *** source: 11313946-Fig-7
  *** P38s[phosAb] phos(TGY)[phosAb] is increased itpo xMlk3
    *** cells: HELA in BMS
    *** inhibited by: xMlk3(K144R) [substitution]
    *** inhibited by: xMlk3(T277A) [substitution]
    *** unaffected by: xMlk3(T278A) [substitution]
    *** partially inhibited by: xMlk3(S281A) [substitution]
    *** source: 11053428-Fig-3b
  *** P38s[phosAb] phos(TGY)[phosAb] is increased itpo xRgl2(mnr)"CAAX"
    *** cells: mEFs<Jnk1~null><Jnk2~null> in BMLS
    *** source: 19647037-Fig-3a
  *** P38s[phosAb] phos(TGY)[phosAb] is increased itpo xRin1(Q78L)
    *** cells: PC6 in BMLS
    *** enhanced by: xBraf [addition]
    *** source: 16157584-Fig-6f
  *** P38s[phosAb] phos(TGY)[phosAb] is increased itpo xRin1(Q78L)
    *** cells: PC6 in BMLS
    *** enhanced by: xBraf [addition]
    *** source: 16157584-Fig-6g
  *** P38s[phosAb] phos(TGY)[phosAb] is increased itpo xRin1(Q78L)
    *** cells: PC6 in BMLS
    *** inhibited by: SB203580 [pretreatment]
    *** source: 16157584-Fig-1c
  *** P38s[phosAb] phos(TGY)[phosAb] is increased itpo xRin1(Q78L)
    *** cells: PC6<xBraf> in BMLS
    *** inhibited by: SB203580 [pretreatment]
    *** source: 16157584-Fig-6f
  *** P38s[phosAb] phos(TGY)[phosAb] is increased itpo xRin1(Q78L)
    *** cells: PC6<xBraf> in BMLS
    *** unaffected by: PD98059 [pretreatment]
    *** source: 16157584-Fig-6g
  *** P38s[phosAb] phos(TGY)[phosAb] is increased itpo xRit1(Q79L)"CA"
    *** cells: COS in BMS
    *** inhibited by: SB203580 [addition]
    *** source: 15632082-Fig-2a
  *** P38s[phosAb] phos(TGY)[phosAb] is increased itpo xRit1(Q79L)"CA"
    *** cells: PC6 in BMLS
    *** inhibited by: SB203580 [addition]
    *** source: 15632082-Fig-2a
  *** P38s[phosAb] phos(TGY)[phosAb] is increased itpo xRit1(Q79L)"CA"
    *** cells: PC6 in BMLS
    *** inhibited by: xRit1(WT) [substitution]
    *** source: 15632082-Fig-1c
  *** P38s[phosAb] phos(TGY)[phosAb] is increased itpo xTab1
    *** cells: HEK293T<xTak1><xUbiq(K63only)> in BMS
    *** inhibited by: xTak1(K158R) [substitution]
    *** unaffected by: xTak1(K34R) [substitution]
    *** source: 20837137-Fig-2
  *** P38s[phosAb] phos(TGY)[phosAb] is increased itpo xTak1
    *** cells: HEK293T<xTab1> in BMS
    *** partially inhibited by: xTak1(T178A) [substitution]
    *** unaffected by: xTak1(T184A) [substitution]
    *** partially inhibited by: xTak1(T178A/T184A) [substitution]
    *** unaffected by: xTak1(T178E/T184E) [substitution]
    *** source: 18617512-Fig-3b
  *** P38s[phosAb] phos(TGY)[phosAb] is increased itpo xUbiq
    *** cells: HEK293T<xTak1> in BMS
    *** unaffected by: xTgfbR1(mnr)"CA" [addition]
    *** unaffected by: xTgfbR1(mnr)"KD" [addition]
    *** source: 18758450-Fig-S3b
  *** xP38s[phosAb] phos(TGY)[phosAb] is unchanged itpo xMek1(mnr)"CA"
    *** cells: COS7<xSumo1> in BMS
    *** source: 17897103-Fig-3a
  *** xP38s[phosAb] phos(TGY)[phosAb] is unchanged itpo xRaf1(mnr)"CA"
    *** cells: COS7<xSumo1> in BMS
    *** source: 17897103-Fig-3a
  *** xP38s[phosAb] phos(TGY)[phosAb] is unchanged itpo xRaf1(mnr)"CA"
    *** cells: COS7<xSumo1> in BMS
    *** source: 17897103-Fig-3b
  *** P38s[phosAb] phos(TGY)[phosAb] is unchanged itpo xRaf1(mnr)"CAAX"
    *** cells: mEFs<Jnk1~null><Jnk2~null> in BMLS
    *** source: 19647037-Fig-3a
  *** P38s[phosAb] phos(TGY)[phosAb] is unchanged itpo xRhoa(Q63L)"CA"
    *** cells: HEK293T in BMLS
    *** source: 11598209-Fig-7a
*** Pabpc1--
  *** Pabpc1[Ab] colocwith[IHC] Stau1[Ab] is detectable
    *** cells: SHSY5Y in BMS "differentiated with retinoic acid for 7 days"
    *** source: 15121898(D)
  *** Pabpc1[Ab] copptby[WB] xStau1[tAb] is detectable
    *** cells: HEK293T in BMS "infected with vaccinia vTf7-3 virus"
    *** source: 15121898(D)
  *** Pabpc1[MS] copptby[WB] xStau1[tAb] is detectable
    *** cells: HEK293T in BMS "infected with vaccinia vTf7-3 virus"
    *** source: 15121898(D)
  *** xPag1[tAb]IP Yphos[pYAb] is decreased itpo xShp2
    *** cells: mEFs<Shp2~null> in BMLS
    *** source: 14967142-Fig-5a
  *** xPag1[tAb]IP Yphos[pYAb] is increased itpo xFyn
    *** cells: COS1 in BMLS
    *** unaffected by: xFyn(Y528F)"CA" [substitution]
    *** inhibited by: xPag1(Y314F) [substitution]
    *** source: 14613929-Fig-3a
*** Pai1-- Pai1-gene--
  *** Pai1-gene mRNA[RTPCR] is unchanged itao Adam17 [RNAi]
    *** cells: HACAT in BMLS
    *** source: 19595713-Fig-5d
  *** Pai1-gene promo-reporter[Luc] is increased itpo xEts1
    *** cells: HEK293T in BMS
    *** source: 18955504-Fig-4f
  *** Pai1-gene promo-reporter[Luc] is increased itpo xMekk1(380-672)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-1a
  *** Pai1-gene promo-reporter[Luc] is increased itpo xSmad3
    *** cells: HEP3B in BMLS
    *** enhanced by: xTfe3 [addition]
    *** source: 12551947-Fig-7c
  *** Pai1-gene promo-reporter[Luc] is increased itpo xSmad3
    *** cells: HEPG2 in BMLS
    *** enhanced by: xTfeb [addition]
    *** source: 12551947-Fig-7b
  *** Pai1-gene promo-reporter[Luc] is increased itpo xSmad3
    *** cells: HEPG2 in BMLS
    *** inhibited by: xMax [addition]
    *** unaffected by: xMax(81-102)"del-Zip" [addition]
    *** source: 12551947-Fig-7a
  *** Pai1-gene promo-reporter[Luc] is increased itpo xSmad3
    *** cells: RGM1 in BMLS
    *** unaffected by: xSmad3(T179V/S204A/S208A/S213A) [substitution]
    *** partially inhibited by: xSmad3(S416A/S422A/S425A) [substitution]
    *** source: 15326485-Fig-8c
  *** Pai1-gene promo-reporter[Luc] is increased itpo xTfe3
    *** cells: HEP3B in BMLS
    *** enhanced by: xSmad3 [addition]
    *** source: 12551947-Fig-7c
  *** Pai1-gene promo-reporter[Luc] is unchanged itpo xJun
    *** cells: HEK293T in BMS
    *** source: 18955504-Fig-4f
  *** Pai1-gene promo-reporter[Luc] is unchanged itpo xMek1(del(32-51)/S218E/S222E)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-1a
  *** Pai1-gene promo-reporter[Luc] is unchanged itpo xTfap2a
    *** cells: HEK293T in BMS
    *** source: 18955504-Fig-4f
  *** Pai1[Ab] prot-exp[WB] is increased itao Pdpk1 [RNAi]
    *** cells: HACAT in BMS "containing Tgfb1"
    *** source: 17327236-Fig-7d
  *** Pai1[Ab] prot-exp[WB] is increased itao Pdpk1 [RNAi]
    *** cells: HELA in BMS "containing Tgfb1"
    *** source: 17327236-Fig-7d
*** Pak1--
  *** xPak1(L107F)[tAb]IP IVKA(Bad)[32P-ATP] is detectable
    *** cells: COS7<xPak1><xPdpk1> in BMS
    *** comment: enhanced by addition of Sphingosine to kinase reaction
    *** source: 10995762-Fig-5
  *** xPak1[Ab] copptby[WB] xRac1(Q61L)"CA"[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 8910292(D)
  *** xPak1[Ab]IP IVKA(MBP)[32P-ATP] is increased itpo xArhGef7
    *** cells: HEK293T<xPak1><xCdc42> in BMLS
    *** inhibited by: xCbl [addition]
    *** source: 16407834-Fig-4e
  *** xPak1[Ab]IP IVKA(MBP)[32P-ATP] is increased itpo xRac1(G12V)"CA"
    *** cells: COS7 in BMS
    *** source: 9032240-Fig-2a
  *** xPak1[Ab]IP prot-exp[WB] is decreased itpo xCdc42
    *** cells: HEK293T<xPak1><xCbl> in BMLS
    *** source: 16407834-Fig-4d
  *** xPak1[Ab]IP prot-exp[WB] is unchanged itpo xRac1
    *** cells: HEK293T<xPak1><xCbl> in BMLS
    *** source: 16407834-Fig-4d
  *** Pak1[phosAb] phos(sitenr)[phosAb] is detectable
    *** cells: mEFs in BMS
    *** reqs: Rac1 [KO]
    *** source: 16698790-Fig-6a,6b
  *** Pak1[phosAb] phos(sitenr)[phosAb] is increased itpo xAkt1(myr)"CA"
    *** cells: mEFs in BMS
    *** source: 16698790-Fig-6b
  *** Pak1[phosAb] phos(sitenr)[phosAb] is unchanged itpo xMek1
    *** cells: mEFs in BMS
    *** source: 16698790-Fig-6b
  *** Pak1[phosAb] phos(sitenr)[phosAb] is unchanged itpo xRock1
    *** cells: mEFs in BMS
    *** source: 16698790-Fig-6b
  *** xPak1[tAb] locatedin(peripheral-focal-complexes)[IHC] is increased itpo xCdc42(G12V/Y40C)
    *** cells: HELA in BMS
    *** source: 9659915-Fig-7b
  *** xPak1[tAb] snaggedby[WB] rRac1(Q61L)"CA"[GST] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-2
  *** xPak1[tAb]IP IVKA(Bad)[32P-ATP] is detectable
    *** cells: COS7<xPak1> in BMS
    *** source: 10995762-Fig-5
  *** xPak1[tAb]IP IVKA(HistH4)[32P-ATP] is increased itpo (xGnb1 + xGng2)
    *** cells: COS7 in BMS
    *** enhanced by: xArhGef6 [addition]
    *** enhanced by: xCdc42 [addition]
    *** source: 12887923-Fig-1c
  *** xPak1[tAb]IP IVKA(HistH4)[32P-ATP] is increased itpo (xGnb1 + xGng2)
    *** cells: COS7 in BMS
    *** enhanced by: xArhGef6 + xCdc42 [addition]
    *** source: 12887923-Fig-1a,1c
  *** xPak1[tAb]IP IVKA(HistH4)[32P-ATP] is increased itpo xRac1(Q61L)"CA"
    *** cells: COS7 in BMLS
    *** source: 16490784(D)
  *** xPak1[tAb]IP IVKA(HistH4)[32P-ATP] is unchanged itpo xArhGef6
    *** cells: COS7 in BMS
    *** source: 12887923-Fig-1c
  *** xPak1[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xDbl
    *** cells: COS7<xPak1> in BMS
    *** source: 9659915-Fig-7c
  *** xPak1[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xRac1(G12V)"CA"
    *** cells: COS7 in BMS
    *** source: 8805275-Fig-3
  *** xPak1[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xRac1(Q61L)"CA"
    *** cells: COS7 in BMS
    *** source: 8910292(D)
  *** xPak1[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xRac1(Q61L)"CA"
    *** cells: COS7 in BMS
    *** unaffected by: xPpp1r9b [addition]
    *** source: 12531897(D)
  *** xPak1[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xTiam1
    *** cells: COS7 in BMS
    *** enhanced by: xRac1 [addition]
    *** unaffected by: xPpp1r9b [addition]
    *** source: 12531897(D)
  *** xPak1[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xRhoa(G14V)"CA"
    *** cells: COS7 in BMS
    *** source: 8805275-Fig-3
  *** xPak1[tAb]IP phos(S21)[phosAb] is increased itpo xRac1(Q61L)"CA"
    *** cells: COS7 in BMLS
    *** source: 16490784(D)
  *** xPak1[tAb]IP phos(T423)[phosAb] is increased by Sphingosine
    *** cells: none
    *** comment: source of xPak1-IP was not reported
    *** comment: inhibited by pretreatment of IP with PP1 or PP2A
    *** source: 10995762-Fig-1b
  *** xPak1[tAb]IP phos(T423)[phosAb] is increased by Sphingosine
    *** cells: none
    *** comment: source of xPak1-IP was not reported
    *** comment: xPak-IP can also rPak1(K299A) on T423
    *** source: 10995762-Fig-2b
  *** xPak1[tAb]IP phos(T423)[phosAb] is increased by Sphingosine
    *** cells: none
    *** comment: source of xPak1-IP was not reported
    *** inhibited by: xPak1(T423A) [substitution]
    *** inhibited by: xPak1(T423E) [substitution]
    *** source: 10995762-Fig-2a
  *** xPak1[tAb]IP phos(T423)[phosAb] is increased itpo xRac1(Q61L)"CA"
    *** cells: COS7 in BMLS
    *** source: 16490784(D)
  *** xPak1[tAb]IP phos[32P-ATP] is increased by Sphingosine
    *** cells: none
    *** comment: source of xPak1-IP was not reported
    *** comment: unaffected by pretreatment of IP with PP1 or PP2A
    *** source: 10995762-Fig-1b
*** Pak2--
  *** Pak2[Ab] copptby[WB] Grb2[Ab] is detectable
    *** cells: HACAT in BMS
    *** source: 12522133-Fig-2b
  *** Pak2[Ab] copptby[WB] Grb2[Ab] is detectable
    *** cells: JURKAT<Pten~null> in BMS
    *** source: 12522133-Fig-2b
  *** Pak2[Ab]IP IVKA(MBP)[32P-ATP] is decreased itpo xErbin
    *** cells: AKR2B in BMLS "treated with Tgfb1 for 45 min"
    *** reqs: Merlin [RNAi]
    *** source: 19289088-Fig-4a
  *** Pak2[Ab]IP IVKA(MBP)[32P-ATP] is detectable
    *** cells: COS7<xTgfbR1><xTgfbR2><xAkt1(K179A)> in BMLS "treated with Tgfb1 for 120 min"
    *** source: 16288034-Fig-5b
  *** Pak2[Ab]IP IVKA(MBP)[32P-ATP] is detectable
    *** cells: COS7<xTgfbR1><xTgfbR2><xPdpk1(mnr)"DN"> in BMLS "treated with Tgfb1 for 120 min"
    *** source: 16288034-Fig-5b
  *** Pak2[Ab]IP IVKA(MBP)[32P-ATP] is increased itpo xCdc42(mnr)"CA"
    *** cells: AKR2B in BMLS
    *** inhibited by: xErbin [addition]
    *** source: 19289088-Fig-5b
  *** Pak2[Ab]IP IVKA(MBP)[32P-ATP] is increased itpo xRac1(mnr)"CA"
    *** cells: AKR2B in BMLS
    *** inhibited by: xErbin [addition]
    *** source: 19289088-Fig-5b
  *** xPak2[phosAb] phos(T402)[phosAb] is increased itpo xCdc42(Q61L)"CA"
    *** cells: 3Y1 in BMS
    *** source: 16129686-Fig-1d
  *** xPak2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xAbi1
    *** cells: COS7 in BMS
    *** inhibited by: xRac1(T17N)"DN" [addition]
    *** source: 11777939-Fig-5
  *** xPak2[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xRac1(Q61L)"CA"
    *** cells: mEFs in BMLS
    *** source: 11524436(D)
  *** xPak2[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xSos1
    *** cells: COS7 in BMS
    *** source: 11777939-Fig-5
*** Pak3--
  *** Pak3[Ab] snaggedby[WB] rPxn[GST] is detectable
    *** cells: 3Y1 in BMS
    *** source: 11096073-Fig-2a
  *** xPak3[Ab]IP IVKA(MBP)[32P-ATP] is increased itpo xArhGef6
    *** cells: COS in BMS
    *** source: 10428811-Fig-1
  *** xPak3[Ab]IP IVKA(MBP)[32P-ATP] is increased itpo xDbl
    *** cells: COS in BMS
    *** source: 10428811-Fig-1
  *** xPak3[Ab]IP IVKA(MBP)[32P-ATP] is increased itpo xTiam1
    *** cells: COS in BMS
    *** source: 10428811-Fig-1
  *** xPak3[Ab]IP IVKA(MBP)[32P-ATP] is increased itpo xVav1
    *** cells: COS in BMS
    *** source: 10428811-Fig-1
  *** xPak3[Ab]IP IVKA(MBP)[32P-ATP] is unchanged itpo xArhGef7
    *** cells: COS in BMS
    *** source: 10428811-Fig-1
  *** xPak3[tAb] copptby[WB] xGit1[tAb] is detectable
    *** cells: COS7<xGit1><xPak3> in BMS
    *** source: 10896954-Fig-9
  *** xPak3[tAb] copptby[WB] xGit2-short[tAb] is detectable
    *** cells: COS7<xGit2-short><xPak3> in BMS
    *** source: 10896954-Fig-9
  *** xPak3[tAb] copptby[WB] xGit2[tAb] is detectable
    *** cells: COS7<xGit2><xPak3> in BMS
    *** source: 10896954-Fig-9
  *** xPak3[tAb] copptby[WB] xPxn[GST] is detectable
    *** cells: COS7 in BMS
    *** inhibited by: xArhGef7 [addition]
    *** source: 11096073-Fig-4b
  *** xPak3[tAb] copptby[WB] xPxn[GST] is detectable
    *** cells: COS7 in BMS
    *** unaffected by: xCdc42 [addition]
    *** source: 11096073-Fig-4c
  *** xPak3[tAb] snaggedby[WB] rRhoa{GDP}[GST] is undetectable
    *** cells: COS in BMS
    *** source: 9305638(D)
  *** xPak3[tAb] snaggedby[WB] rRhoa{GTPgS}[GST] is undetectable
    *** cells: COS in BMS
    *** source: 9305638(D)
  *** xPak3[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xArhGef6
    *** cells: COS7<xArhGef6> in BMLS
    *** unaffected by: xArhGef6(1-614)"CH.PXXP" [substitution] 
    *** source: 15306850-Fig-4b
  *** xPak3[tAb]IP IVKA(MBP)[32P-ATP] is increased itpo xArhGef6
    *** cells: COS7<xArhGef6> in BMLS
    *** unaffected by: xArhGef6(154-541)"SH3.PH" [substitution]
    *** inhibited by: xArhGef6(433-759)"PH,LZ" [substitution]
    *** unaffected by: xArhGef6(mnr)"SH3.CBD" [substitution]
    *** inhibited by: xArhGef6(L543R/I544V)"LIm" [substitution]
    *** inhibited by: xArhGef6(L383R/L384R)"DHm" [substitution]
    *** inhibited by: xArhGef6(W194K/W195K)"WWm" [substitution]
    *** source: 15306850-Fig-3c
  *** xPak3[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xHras(G12V)"CA"
    *** cells: COS in BMS
    *** source: 11259591-Fig-5b
  *** xPak3[tAb]IP IVKA(MBP)[32P-ATP] is unchanged itpo xSrc(Y530F)"CA"
    *** cells: COS in BMS
    *** source: 11259591-Fig-5b
*** Pak6--
  *** xPak6[tAb] snaggedby[WB] rCdc42(Q61L)"CA"[GST] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-2
  *** xPak6[tAb] snaggedby[WB] rRac1(Q61L)"CA"[GST] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-2
  *** xPak6[tAb] snaggedby[WB] rRhoa(Q63L)"CA"[GST] is undetectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-2
  *** xPak6[tAb] snaggedby[WB] rRhog(Q61L)"CA"[GST] is undetectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-2
*** Pak7--
  *** xPak7[tAb] snaggedby[WB] rCdc42(Q61L)"CA"[GST] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-2
  *** xPak7[tAb] snaggedby[WB] rRac1(Q61L)"CA"[GST] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-2
  *** xPak7[tAb] snaggedby[WB] rRhoa(Q63L)"CA"[GST] is undetectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-2
  *** xPak7[tAb] snaggedby[WB] rRhog(Q61L)"CA"[GST] is undetectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-2
*** Pamci--
  *** xPamci[tAb] copptby[WB] xHras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xHras(G12V/D38A) [substitution]
    *** inhibited by: xHras(G12V/T35S) [substitution]
    *** inhibited by: xHras(G12V/E37G) [substitution]
    *** inhibited by: xHras(G12V/Y40C) [substitution]
    *** inhibited by: xHras(G12V/D38E) [substitution]
    *** source: 15143186-Fig-6
  *** xPamci[tAb] copptby[WB] xHras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186(D)
  *** xPamci[tAb] copptby[WB] xKras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xPamci[tAb] copptby[WB] xMras(Q71L)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xPamci[tAb] copptby[WB] xNras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xPamci[tAb] copptby[WB] xRap1a(G12V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xPamci[tAb] copptby[WB] xRap2a(G12V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xPamci[tAb] copptby[WB] xRras(G38V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xPamci[tAb] copptby[WB] xRras2(G23V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
*** Pard6a--
  *** xPard6a[tAb] snaggedby[WB] rCdc42(Q61L)"CA"[GST] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-2
  *** xPard6a[tAb] snaggedby[WB] rRac1(Q61L)"CA"[GST] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-2
  *** xPard6a[tAb] snaggedby[WB] rRhoa(Q63L)"CA"[GST] is undetectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-2
  *** xPard6a[tAb] snaggedby[WB] rRhog(Q61L)"CA"[GST] is undetectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-2
*** Parp1--
  *** Parp1[Ab] cleavage[WB] is detectable
    *** cells: MCF7 in BMS
    *** unaffected by: Cdkn1b [RNAi]
    *** source: 17237771(D)
  *** rParp1[Ab] cleavage[WB] is increased by rCasp1
    *** cells: none
    *** source: 9121587-Table-1
  *** rParp1[Ab] cleavage[WB] is increased by rCasp2
    *** cells: none
    *** source: 9121587-Table-1
  *** rParp1[Ab] cleavage[WB] is increased by rCasp3
    *** cells: none
    *** source: 9121587-Table-1
  *** rParp1[Ab] cleavage[WB] is increased by rCasp4
    *** cells: none
    *** source: 9121587-Table-1
  *** rParp1[Ab] cleavage[WB] is increased by rCasp5
    *** cells: none
    *** source: 9121587-Table-1
  *** rParp1[Ab] cleavage[WB] is increased by rCasp6
    *** cells: none
    *** source: 9121587-Table-1
  *** rParp1[Ab] cleavage[WB] is increased by rCasp7
    *** cells: none
    *** source: 9121587-Table-1
  *** Parp1[Ab] cleavage[WB] is increased itao Cdkn1b [RNAi]
    *** cells: MCF7 in BMLS
    *** inhibited by: Methylpyruvate [addition]
    *** source: 17237771(D)
  *** Parp1[Ab] cleavage[WB] is increased itao Mavs [KO]
    *** cells: HEK293 in BMS
    *** source: 16125763-Fig-S6
  *** rParp1[MS] cleavage[WB] is increased by rCasp1
    *** cells: none
    *** source: 17959595(D)
  *** rParp1[MS] cleavage[WB] is increased by rCasp3
    *** cells: none
    *** source: 17959595(D)
  *** Parp14[Ab] copptby[WB] Stat6[Ab] is detectable
    *** cells: M12 in BMS
    *** unaffected by: IL4 (tnr) [stim]
    *** source: 16537510-Fig-1c
  *** Parp14[Ab] infraction(nuclear)[WB] is detectable
    *** cells: M12 in BMS
    *** unaffected by: IL4 (tnr) [stim]
    *** source: 16537510-Fig-1c
*** Pdgfa-- ProPdgfa-gene--
*** PdgfR--
  *** xPdgfR[Ab] copptby[WB] xSnx6[tAb] is detectable
    *** cells: COS7 in BMLS
    *** source: 11279102(D)
  *** PdgfRb[Ab] prot-exp[WB] is detectable
    *** cells: OCIMY5 in BMS
    *** reqs: Deptor [RNAi]
    *** source: 19446321-Fig-6e
  *** PdgfRb[Ab] prot-exp[WB] is detectable
    *** cells: OCIMY5 in BMS
    *** reqs: Tsc1 and/or Tsc2 [RNAi]
    *** source: 19446321-Fig-S8
*** Pdpk1--
  *** Pdpk1[Ab] copptby[WB] xAkt1[tAb] is increased itpo xFreud1
    *** cells: HEK293T in BMS
    *** source: 18662999-Fig-4f
  *** xPdpk1[Ab] locatedin(cellmembrane)[IHC] is increased itpo xPik3cg(mnr)"CA"
    *** cells: COS7<xPdk1> in BMLS
    *** inhibited by: xPik3cg(mnr)"KD" [substitution]
    *** source: 9637919-Fig-3
  *** xPdpk1[Ab] locatedin(cytoplasm)[IHC] is detectable
    *** cells: PAE<xPdk1> in BMLS
    *** source: 9637919-Fig-1
  *** Pdpk1[Ab]IP IVKA(LKBtide)[32P-ATP] is detectable
    *** cells: mESCs in BMLS
    *** source: 10801415-Fig-1c
  *** Pdpk1[Ab]IP IVKA(Sgk1)[32P-ATP] is detectable
    *** cells: HEK293T in BMS
    *** does not req: Freud1 [RNAi]
    *** source: 18662999-Fig-3d
  *** Pdpk1[Ab]IP Yphos[pYAb] is detectable
    *** cells: HT1080 in BMLS "refed and treated with Egf for 10 min"
    *** inhibited by: xNprl2 [addition]
    *** unaffected by: xNprl2(134-380)"dN133" [addition]
    *** source: 18616680-Fig-4b
  *** xPdpk1[GST]IP IVKA(Sgk1)[32P-ATP] is detectable
    *** cells: HEK293T in BMS
    *** reqs: Smad3 [RNAi]
    *** reqs: Smad7 [RNAi]
    *** source: 17327236-Fig-4d
  *** xPdpk1[GST]IP IVKA(Sgk1)[32P-ATP] is increased itpo xSmad2
    *** cells: HEK293T in BMS
    *** source: 17327236-Fig-4a
  *** xPdpk1[GST]IP IVKA(Sgk1)[32P-ATP] is increased itpo xSmad3
    *** cells: HEK293T in BMS
    *** source: 17327236-Fig-4a
  *** xPdpk1[GST]IP IVKA(Sgk1)[32P-ATP] is increased itpo xSmad7
    *** cells: HEK293T in BMS
    *** source: 17327236-Fig-4a
  *** xPdpk1[GST]IP IVKA(Sgk1)[32P-ATP] is increased itpo xStrap
    *** cells: HEK293T in BMS
    *** source: 17327236-Fig-4a
  *** xPdpk1[phosAb] phos(Y9)[phosAb] is increased itpo xFak2
    *** cells: HEK293<xPdpk1> in BMS
    *** inhibited by: xFak2(K457A) [substitution]
    *** source: 14585963-Fig-4a
  *** xPdpk1[phosAb] phos(Y373/Y376)[phosAb] is increased itpo xFak2
    *** cells: HEK293<xPdpk1> in BMS
    *** inhibited by: xFak2(K457A) [substitution]
    *** source: 14585963-Fig-4a
  *** xPdpk1[tAb] copptby[WB] xNprl2[tAb] is detectable
    *** cells: HEK293T<xNprl2><xPdpk1> in BMS
    *** unaffected by: xNprl2(1-102)"dC103" [substitution]
    *** partially inhibited by: xNprl2(1-198)"dC199" [substitution]
    *** partially inhibited by: xNprl2(1-294)"dC295" [substitution]
    *** partially inhibited by: xNprl2(104-380)"dN103" [substitution]
    *** inhibited by: xNprl2(134-380)"dN133" [substitution]
    *** inhibited by: xNprl2(174-380)"dN173" [substitution]
    *** source: 18616680-Fig-2a
  *** xPdpk1[tAb] copptby[WB] xPkn2[GST] is detectable
    *** cells: COS7<xPdpk1><xPkn2> in BMLS "treated with Egf for 35 min"
    *** inhibited by: xPdpk1(R131A) [substitution]
    *** inhibited by: xPdpk1(R131D) [substitution]
    *** source: 12374740-Fig-3a
  *** xPdpk1[tAb] copptby[WB] xRsk3(1-389)[tAb] is detectable
    *** cells: COS7<xRsk3(1-389)><xPdpk1> in BMLS
    *** comment: inhibited by removal of phosphatase inhibitors from lysis buffer
    *** source: 10856237-Fig-6b
  *** xPdpk1[tAb] copptby[WB] xRsk3(1-389)[tAb] is detectable
    *** cells: COS7<xRsk3(1-389)><xPdpk1> in BMLS
    *** inhibited by: xRsk3(1-389/S386A) [substitution]
    *** inhibited by: xRsk3(1-380) [substitution]
    *** source: 10856237-Fig-6a
  *** xPdpk1[tAb] copptby[WB] xRsk3(375-740)[tAb] is detectable
    *** cells: COS7<xRsk3(375-740)><xPdpk1> in BMLS
    *** inhibited by: xRsk3(416-740) [substitution]
    *** source: 10856237-Fig-6c
  *** xPdpk1[tAb] copptby[WB] xRsk3(375-740)[tAb] is increased itpo xMek1(S218E/S222E)
    *** cells: COS7<xRsk3(375-740)><xPdpk1> in BMLS
    *** source: 10856237-Fig-6c
  *** xPdpk1[tAb] copptby[WB] xRsk3[tAb] is detectable
    *** cells: COS7<xRsk3><xPdpk1> in BMLS
    *** inhibited by: xRsk3(S386K) [substitution]
    *** source: 10856237-Fig-5
  *** xPdpk1[tAb] copptby[WB] xSmad2[GST] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xPdk1(67-359)"CatDom" [substitution]
    *** partially inhibited by: xPdk1(411-556)"PHDom" [substitution]
    *** source: 17327236-Fig-2a
  *** xPdpk1[tAb] copptby[WB] xSmad2[GST] is detectable
    *** cells: HEPG2 in BMS
    *** unaffected by: xPdpk1(mnr)"KD" [substitution]
    *** source: 17327236-Fig-7c
  *** xPdpk1[tAb] copptby[WB] xSmad3[GST] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xPdk1(67-359)"CatDom" [substitution]
    *** unaffected by: xPdk1(411-556)"PHDom" [substitution]
    *** source: 17327236-Fig-2a
  *** xPdpk1[tAb] copptby[WB] xSmad3[GST] is detectable
    *** cells: HEPG2 in BMS
    *** unaffected by: xPdpk1(mnr)"KD" [substitution]
    *** source: 17327236-Fig-7c
  *** xPdpk1[tAb] copptby[WB] xSmad4[GST] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xPdk1(67-359)"CatDom" [substitution]
    *** unaffected by: xPdk1(411-556)"PHDom" [substitution]
    *** source: 17327236-Fig-2a
  *** xPdpk1[tAb] copptby[WB] xSmad4[GST] is detectable
    *** cells: HEPG2 in BMS
    *** unaffected by: xPdpk1(mnr)"KD" [substitution]
    *** source: 17327236-Fig-7c
  *** xPdpk1[tAb] copptby[WB] xSmad7[GST] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xPdk1(67-359)"CatDom" [substitution]
    *** partially inhibited by: xPdk1(411-556)"PHDom" [substitution]
    *** source: 17327236-Fig-2a
  *** xPdpk1[tAb] copptby[WB] xSmad7[GST] is detectable
    *** cells: HEPG2 in BMS
    *** unaffected by: xPdpk1(mnr)"KD" [substitution]
    *** source: 17327236-Fig-7c
  *** xPdpk1[tAb] phos[WBMS] is increased itpo xRsk3
    *** cells: COS7<xPdpk1> in BMLS
    *** enhanced by: xRsk3(1-389) [substitution]
    *** enhanced by: xRsk3(1-380/mnr)"KD" [substitution]
    *** inhibited by: xRsk3(1-389/S386A) [substitution]
    *** source: 10856237-Fig-8a
  *** xPdpk1[tAb] phos[WBMS] is increased itpo xRsk3
    *** cells: COS7<xPdpk1> in BMLS
    *** inhibited by: xPdpk1(mnr)"KD" [substitution]
    *** source: 10856237-Fig-8a
  *** xPdpk1[tAb] phos[WBMS] is increased itpo xRsk3
    *** cells: COS7<xPdpk1> in BMLS
    *** inhibited by: xRsk3(375-740) [substitution]
    *** unaffected by: xRsk3(375-740) + xMek1(S218E/S222E) [substitution]
    *** source: 10856237-Fig-8a
  *** xPdpk1[tAb] phos[WBMS] is increased itpo xRsk3
    *** cells: COS7<xPdpk1> in BMLS
    *** inhibited by: xRsk3(S386K) [substitution]
    *** inhibited by: xRsk3(416-740) [substitution]
    *** source: 10856237-Fig-8a
  *** xPdpk1[tAb] phos[WBMS] is increased itpo xRsk3(1-389)
    *** cells: COS7<xPdpk1> in BMLS
    *** inhibited by: xPdpk1(mnr)"KD" [substitution]
    *** source: 10856237-Fig-8a
  *** xPdpk1[tAb]IP IVKA(auto)[32P-ATP] is increased by rRsk3(373-396){phos}
    *** cells: none
    *** IPfrom: COS7<xPdpk1> in BMLS
    *** comment: this also works on rRsk3(1-360) as a substrate
    *** comment: but not rRsk3(1-360/S227E)
    *** inhibited by: rRsk3(373-396) [substitution]
    *** source: 10856237-Fig-10c
  *** xPdpk1[tAb]IP IVKA(auto)[32P-ATP] is increased by rRsk3(373-396){phos}
    *** cells: none
    *** IPfrom: COS7<xPdpk1> in BMLS
    *** inhibited by: rRsk3(373-396) [substitution]
    *** source: 10856237-Fig-9a
  *** xPdpk1[tAb]IP IVKA(Pak1)[32P-ATP] is detectable
    *** cells: COS7<xPdpk1> in BMLS
    *** enhanced by: Sphingomyelinase (30 min) [stim]
    *** source: 10995762-Fig-7
  *** xPdpk1[tAb]IP phos[32P-ATP] is increased by pSrc(mnr)"vSrc"
    *** cells: HEK293T<xPdpk1> in BMS
    *** comment: most of the phos was on Tyrosine [TLC]
    *** comment: phos sites were Y9 T33 S410 Y373 T513 S241 Y485 by HPLC
    *** source: 11481331-Fig-7a
  *** xPdpk1[tAb]IP Yphos[pYAb] is increased itpo xFak2
    *** cells: CHO<xAgtR1><xPdpk1> in BMS
    *** inhibited by: xFak2(K457A) [substitution]
    *** source: 14585963-Fig-3b
  *** xPdpk1[tAb]IP Yphos[pYAb] is increased itpo xFak2
    *** cells: CHO<xAgtR1><xPdpk1> in BMS
    *** inhibited by: xPdpk1(Y9F) [substitution]
    *** source: 14585963-Fig-4c
  *** xPdpk1[tAb]IP Yphos[pYAb] is increased itpo xFak2
    *** cells: HEK293<xPdpk1> in BMS
    *** inhibited by: PP1 [pretreatment]
    *** source: 14585963-Fig-5c
  *** xPdpk1[tAb]IP Yphos[pYAb] is increased itpo xFak2
    *** cells: HEK293<xPdpk1> in BMS
    *** inhibited by: xFak2(K457A) [substitution]
    *** inhibited by: xFak2(Y402F) [substitution]
    *** source: 14585963-Fig-3c
  *** xPdpk1[tAb]IP Yphos[pYAb] is increased itpo xFak2
    *** cells: HEK293<xPdpk1> in BMS
    *** inhibited by: xSrc(K296R/Y528F)"DN" [addition]
    *** source: 14585963-Fig-5c
  *** xPdpk1[tAb]IP Yphos[pYAb] is increased itpo xSrc(mnr)"vSrc"
    *** cells: HEK293T<xPdpk1> in BMS
    *** inhibited by: xSrc(mnr)"vSrc-KD" [substitution]
    *** source: 11481331-Fig-6a
  *** xPdpk1[tAb]IP Yphos[pYAb] is unchanged itpo xFyn
    *** cells: HEK293T<xPdpk1> in BMS
    *** source: 11481331-Fig-6a
  *** xPdpk1[tAb]IP Yphos[pYAb] is unchanged itpo xInsR
    *** cells: HEK293T<xPdpk1> in BMS
    *** source: 11481331-Fig-6a
*** Pea15--
  *** xPea15(I15A)[Ab] infraction(cytoplasmic)[WB] is detectable
    *** cells: CHO<xPea15> in BMLS
    *** inhibited by: xPea15(WT) [substitution]
    *** source: 11702783-Fig-4d
  *** rPea15[32P] phos[32P-ATP] is increased by pPkcs
    *** cells: none
    *** source: 11702783-Fig-6c
  *** rPea15[32P] phos[32P-ATP] is unchanged by xErks{act}[Ab]IP
    *** cells: none
    *** IPfrom: NIH3T3 in BMS "treated with serum for 10 min"
    *** source: 11702783-Fig-6c
  *** xPea15[Ab] copptby[WB] xErks[tAb] is detectable
    *** cells: CHO<xPea15><xErk2> in BMS
    *** source: 11702783-Fig-5d
  *** rPea15[tAb] boundby[WB] rErk2[GST] is detectable
    *** cells: none
    *** enhanced by: rErk2(D316A/D319A) [substitution]
    *** inhibited by: rErk2(del(241-272)) [substitution]
    *** source: 14707138-Fig-1c
  *** xPea15[tAb] copptby[WB] xNod1[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 10329646(D)
*** Peli1--
  *** xPeli1[tAb] copptby[WB] Ripk1[Ab] is detectable
    *** cells: HEK293<xPeli1> in BMS
    *** unaffected by: xTrif [addition]
    *** source: 19734906-Fig-6c
  *** xPeli1[tAb] copptby[WB] xIrak1[Ab] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xIrak1(K240N)"KD" [substitution]
    *** source: 16884718-Fig-2a
  *** xPeli1[tAb] copptby[WB] xRipk1[tAb] is detectable
    *** cells: HEK293<xPeli1><xRipk1> in BMS
    *** source: 19734906-Fig-6b
  *** xPeli1[tAb] phos[WBMS-PPase] is increased itpo xIrak1
    *** cells: HEK293T<xUbiq> in BMS
    *** source: 16884718-Fig-3a
  *** xPeli1[tAb]IP ubiq[UbAb] is increased itpo xIrak1
    *** cells: HEK293 in BMS
    *** inhibited by: xIrak1(mnr)"KD" [substitution]
    *** source: 17675297-Fig-2
*** Peli2--
  *** xPeli2[Ab] upshift[WBMS] is detectable
    *** cells: HEK293<Irak1~null><xIL1R1><xIrak1> in BMLS
    *** inhibited by: xIrak1(K239A)"KD" [substitution]
    *** inhibited by: xPeli2(H371S/C373A)"ring-domain-mut" [substitution]
    *** source: 17997719-Fig-5a
  *** xPeli2[tAb] copptby[WB] Bcl10[Ab] is decreased itpo xSocs3
    *** cells: RAW2647 in BMS "treated with Lps (30 min)"
    *** source: 15213237-Fig-9a
  *** xPeli2[tAb] copptby[WB] xIrak1[Ab] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xIrak1(K240N)"KD" [substitution]
    *** source: 16884718-Fig-2a
  *** xPeli2[tAb] copptby[WB] xSocs3[Ab] is detectable
    *** cells: RAW2647 in BMS "treated with Lps (30 min)"
    *** source: 15213237-Fig-9b
  *** xPeli2[tAb] phos[WBMS-PPase] is increased itpo xIrak1
    *** cells: HEK293T<xUbiq> in BMS
    *** source: 16884718-Fig-3a
  *** xPeli2[tAb]IP ubiq[UbAb] is increased itpo xIrak1
    *** cells: HEK293 in BMS
    *** inhibited by: xIrak1(mnr)"KD" [substitution]
    *** source: 17675297-Fig-2
*** Peli3--
  *** xPeli3[tAb] copptby[WB] xIrak1[Ab] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xIrak1(K240N)"KD" [substitution]
    *** source: 16884718-Fig-2a
  *** xPeli3[tAb] phos[WBMS-PPase] is increased itpo xIrak1
    *** cells: HEK293T<xUbiq> in BMS
    *** source: 16884718-Fig-3a
  *** xPeli3[tAb]IP ubiq[UbAb] is increased itpo xIrak1
    *** cells: HEK293 in BMS
    *** inhibited by: xIrak1(mnr)"KD" [substitution]
    *** inhibited by: xPeli3(Y44A)"Irak1-binding-mut" [substitution]
    *** source: 17675297-Fig-2
*** Pex1--
  *** Pex1[MS] copptby[WB] Sin1[Ab] is detectable
    *** cells: HELA in BMS
    *** source: 16962653-Fig-1a
*** Pfkfb2--
  *** pPfkfb2[32P] phos[32P-ATP] is increased by pPkcs
    *** cells: none
    *** source: 1322130(D)
  *** Pfkfb2[Ab] copptby[WB] Ywhas[Ab] is detectable
    *** cells: HELA in BMS
    *** source: 12853467(D)
  *** rPhb boundby[SPR] rBraf[RU] is undetectable
    *** cells: none
    *** source: 16041367-Fig-S4b
  *** rPhb boundby[SPR] rHras{GDPbS}[RU] is undetectable
    *** cells: none
    *** source: 16041367-Fig-S4b
  *** rPhb boundby[SPR] rHras{GTPgS}[RU] is undetectable
    *** cells: none
    *** source: 16041367-Fig-S4b
  *** rPhb boundby[SPR] rRaf1[RU] is detectable
    *** cells: none
    *** source: 16041367-Fig-S4b
*** Phb--
  *** Pi3k[Ab]IP IVLKA(PtdIns)[TLC] is increased itpo xRasa1((1-445)/D157A)"Casp-resistant"
    *** cells: HELA in BMS
    *** unaffected by: xRasa1(456-1047)"Cterm" [addition]     
    *** source: 11847220-Fig-3a
  *** Pi3k[Ab]IP IVLKA(PtdIns)[TLC] is unchanged itpo xRasa1(456-1047)"Cterm"
    *** cells: HELA in BMS
    *** source: 11847220-Fig-3a
*** Pias1--
  *** xPias1[tAb] copptby[WB] E2f1[Ab] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15657437-Fig-1b
  *** xPias1[tAb] copptby[WB] xNfkb1(1-433)[Ab] is undetectable
    *** cells: HEK293T<xPias1><xNfkb1(1-433)> in BMS
    *** source: 15657437-Fig-1c
  *** xPias1[tAb] copptby[WB] xRela[Ab] is detectable
    *** cells: HEK293T<xPias1><xRela> in BMS
    *** inhibited by: xRela(1-313) [substitution]
    *** unaffected by: xRela(299-551) [substitution]
    *** source: 15657437-Fig-1d
  *** xPias1[tAb] copptby[WB] xRela[Ab] is detectable
    *** cells: HEK293T<xPias1><xRela> in BMS
    *** source: 15657437-Fig-1b
  *** xPias1[tAb] copptby[WB] xRela[Ab] is detectable
    *** cells: HEK293T<xPias1><xRela> in BMS
    *** source: 15657437-Fig-1c
  *** xPias1[tAb] copptby[WB] xRela[Ab] is detectable
    *** cells: HEK293T<xPias1><xRela> in BMS
    *** unaffected by: Tnf (15 min) [stim]
    *** source: 15657437-Fig-1a
  *** xPias1[tAb] copptby[WB] xRela[Ab] is detectable
    *** cells: HEK293T<xPias1><xRela> in BMS
    *** unaffected by: xPias1(1-415) [substitution]
    *** unaffected by: xPias1(1-344) [substitution]
    *** unaffected by: xPias1(89-344) [substitution]
    *** inhibited by: xPias1(416-650) [substitution]
    *** source: 15657437-Fig-1e
  *** xPias1[tAb] copptby[WB] xStat1[tAb] is detectable
    *** cells: U3A<Stat1~null> in BMS
    *** unaffected by: xStat1(K410Q/K413Q) [substitution]
    *** source: 19171783-Fig-S3b
  *** xPias2[Ab] copptby[WB] xMyc[Ab] is detectable
    *** cells: HELA in BMS
    *** source: 9312026-Fig-2b
  *** xPias2[tAb] locatedin(nucleus)[IHC] is detectable
    *** cells: 2FTGH<xPias2> in BMS
    *** source: 12716907-Fig-1b
  *** rPias2a[32P] phos[32P-ATP] is unchanged by rErk2{act}
    *** cells: none
    *** source: 16713578-Fig-3d
  *** rPias2a[32P] phos[32P-ATP] is unchanged by rJnk2{act}
    *** cells: none
    *** source: 16713578-Fig-3d
  *** Pias2a[Ab] copptby[WB] Elk1[Ab] is detectable
    *** cells: HELA in BMS
    *** source: 15920481-Fig-4b
  *** xPias2a[tAb] copptby[WB] xElk1[Ab] is detectable
    *** cells: HEK293<xPias2a><xElk1> in BMLS
    *** inhibited by: xPias2a(103-572) [substitution]
    *** inhibited by: xPias2a(304-572) [substitution]
    *** source: 15920481-Fig-6d
  *** xPias2a[tAb] copptby[WB] xElk1[Ab] is detectable
    *** cells: HEK293<xPias2a><xElk1> in BMLS
    *** source: 15920481-Fig-4a
  *** xPias2a[tAb] copptby[WB] xElk1[Ab] is detectable
    *** cells: HEK293<xPias2a><xElk1> in BMLS
    *** unaffected by: xElk1(K230R/K249R) [substitution]
    *** source: 15920481-Fig-4d
  *** xPias2a[tAb] copptby[WB] xElk1[Ab] is detectable
    *** cells: HEK293<xPias2a><xElk1> in BMLS
    *** unaffected by: xPias2(del(467-487)) [substitution]
    *** source: 15920481-Fig-4c
  *** xPias2a[tAb] phos[WBMS] is detectable
    *** cells: HEK293<xPias2a> in BMS
    *** inhibited by: xPias2a(S113A/S116A) [substitution]
    *** inhibited by: xPias2a(S113A/S116A/S136A/T184A) [substitution]
    *** inhibited by: xPias2a(S50A/S90A/S113A/S116A/S136A/T184A/S499A/T539A/S550A) [substitution]
    *** unaffected by: xPias2a(S50A/S90A/S136A/T184A/S499A/T539A/S550A) [substitution]
    *** source: 16713578-Fig-4b
  *** xPias2a[tAb] phos[WBMS] is detectable
    *** cells: HEK293<xPias2a> in BMS
    *** inhibited by: xPias2a(S113A/S116A) [substitution]
    *** unaffected by: xPias2a(S113A) [substitution]
    *** unaffected by: xPias2a(S116A) [substitution]
    *** source: 16713578-Fig-4c
  *** xPias2a[tAb] phos[WBMS] is detectable
    *** cells: HEK293<xPias2a> in BMS
    *** unaffected by: xPias2a(S113A) [substitution]
    *** unaffected by: xPias2a(S116A) [substitution]
    *** unaffected by: xPias2a(S50A/S90A/S136A/T184A/S499A/T539A/S550A) [substitution]
    *** inhibited by: xPias2a(S50A/S90A/S113A/S116A/S136A/T184A/S499A/T539A/S550A) [substitution]
    *** source: 16713578-Fig-4d
  *** rPias3[35S] boundby[WB] rMitf[GST] is detectable
    *** cells: none
    *** inhibited by: rPias3(82-156)"D5" [addition]
    *** unaffected by: rPias3(444-585)"D4" [addition]
    *** source: 15572665-Fig-1d
  *** rPias3[35S] boundby[WB] rMitf[GST] is detectable
    *** cells: none
    *** unaffected by: rPias3(1-143)"D1" [substitution]
    *** unaffected by: rPias3(144-286)"D2" [substitution]
    *** inhibited by: rPias3(287-443)"D3" [substitution]
    *** inhibited by: rPias3(444-585)"D4" [substitution]
    *** source: 15572665-Fig-1b
  *** rPias3[35S] boundby[WB] rMitf[GST] is detectable
    *** cells: none
    *** unaffected by: rPias3(82-156)"D5" [substitution]
    *** source: 15572665-Fig-1c
  *** rPias3[35S] boundby[WB] rStat3[GST] is detectable
    *** cells: none
    *** inhibited by: rPias3(82-156)"D5" [addition]
    *** unaffected by: rPias3(444-585)"D4" [addition]
    *** source: 15572665-Fig-1d
  *** rPias3[35S] boundby[WB] rStat3[GST] is detectable
    *** cells: none
    *** unaffected by: rPias3(1-143)"D1" [substitution]
    *** unaffected by: rPias3(144-286)"D2" [substitution]
    *** inhibited by: rPias3(287-443)"D3" [substitution]
    *** inhibited by: rPias3(444-585)"D4" [substitution]
    *** source: 15572665-Fig-1b
  *** rPias3[35S] boundby[WB] rStat3[GST] is detectable
    *** cells: none
    *** unaffected by: rPias3(82-156)"D5" [substitution]
    *** source: 15572665-Fig-1c
  *** xPias3[XFP] locatedin(nucleus)[IHC] is detectable
    *** cells: B16<xMitf><xStat3> in BMS
    *** source: 15572665-Fig-7a
  *** xPias3[XFP] locatedin(nucleus)[IHC] is detectable
    *** cells: NIH3T3<xMitf><xStat3> in BMS
    *** source: 15572665-Fig-5a
*** Pias4--
  *** rPias4[35S] boundby[WB] rSmad4[GST] is detectable
    *** cells: none
    *** source: 12904571-Fig-1e
  *** xPias4[tAb] copptby[WB] xTcf7l2(del(128-150))[tAb] is detectable
    *** cells: HEK293<xSumo1> in BMS
    *** source: 12727872-Fig-3a
*** Pik3--
*** Pik3c--
*** Pik3c2b--
  *** xPik3c2b[Ab] copptby[WB] Eps8[Ab] is detectable
    *** cells: A431 in BMLS "Triton-Insoluble fraction"
    *** unaffected by: Egf (5,30,60,120,240,360,480 min) [stim]
    *** source: 16775008-Fig-2b
  *** xPik3c2b[Ab] copptby[WB] Grb2[Ab] is detectable
    *** cells: A431 in BMLS
    *** source: 16775008-Fig-1g
  *** xPik3c2b[Ab] copptby[WB] Grb2[Ab] is detectable
    *** cells: A431 in BMLS "Triton-Insoluble fraction"
    *** unaffected by: Egf (5,30,120,240 min) [stim]
    *** source: 16775008-Fig-3a
*** Pik3ca--
  *** Pik3ca[MS] copptby[WB] xMras(H81L)"CA"[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 16630891-Fig-1a
  *** xPik3ca[tAb] snaggedby[WB] rMras{GTP}[GST] is detectable
    *** cells: NIH3T3 in BMS
    *** inhibited by: rMras{GTP} [substitution]
    *** source: 10803462-Fig-5a
*** Pik3cb--
  *** Pik3cb[Ab] copptby[WB] xRras(G38V)"CA"[tAb] is undetectable
    *** cells: NIH3T3 in BMLS
    *** source: 11340168-Fig-4a
  *** Pik3cb[Ab] copptby[WB] xRras2(G23V)"CA"[tAb] is detectable
    *** cells: NIH3T3 in BMLS
    *** inhibited by: xRras2(G23V/E48G) [substitution]
    *** inhibited by: xRras2(G23V/E46S) [substitution]
    *** inhibited by: xRras2(G23V/Y51C) [substitution]
    *** source: 11340168-Fig-4b
  *** Pik3cb[Ab] copptby[WB] xRras2(G23V)"CA"[tAb] is detectable
    *** cells: NIH3T3 in BMLS
    *** source: 11340168-Fig-4a
  *** xPik3cb[tAb]IP IVLKA(PtdIns)[TLC] is detectable
    *** cells: COS in BMS
    *** inhibited by: xPik3cb(K805R) [substitution]
    *** source: 11916960(D)
*** Pik3r--
  *** xPik3r?[Ab] copptby[WB] xAbi1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 12515821-Fig-S1b
*** Pik3r1--
  *** xPik3r1[Ab] copptby[WB] xGab1[Ab] is detectable
    *** cells: HEK293<xGab2><xPik3r1> in BMS "treated with Hgf + PAO for tnr"
    *** unaffected by: xGab1(116-694) [substitution]
    *** unaffected by: xGab1(del(242-411))"dCrk" [substitution]
    *** partially inhibited by: xGab1(Y448F/Y473F/Y590F)"dPi3k" [substitution]
    *** unaffected by: xGab1(Y682F)"dShp2" [substitution]
    *** unaffected by: xGab1(450-694) [substitution]
    *** inhibited by: xGab1((450-694)/Y473F/Y590F) [substitution]
    *** source: 10871282-Fig-4b
  *** Pik3r1[MS] copptby[WB] xMras(H81L)"CA"[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 16630891-Fig-1a
*** Pik3r2--
  *** Pik3r2[MS] copptby[WB] xMras(H81L)"CA"[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 16630891-Fig-1a
  *** Pik3rs[Ab] copptby[WB] Abi1[Ab] is detectable
    *** cells: mEFs in BMS
    *** source: 12515821-Fig-1a
  *** Pik3rs[Ab] copptby[WB] Shc1[Ab] is detectable
    *** cells: 16E6P in BMS "Egf deprived"
    *** enhanced by: Egf (10 min) [stim]
    *** source: 8662998-Fig-4
  *** Pik3rs[Ab] copptby[WB] xAbi1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xAbi1(Y407F) [substitution]
    *** source: 12515821-Fig-1e
  *** Pik3rs[Ab] copptby[WB] xCbl[Ab] is increased itpo xHck(Y522F)"CA"
    *** cells: HEK293T in BMS
    *** inhibited by: xCbl(Y731F) [substitution]
    *** source: 10799548-Fig-5b
  *** Pik3rs[Ab] copptby[WB] xEps8[tAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xAbi1(Y407F) [substitution]
    *** source: 12515821-Fig-3a
  *** Pik3rs[Ab] copptby[WB] xLck(Y505F)"CA"[Ab] is detectable
    *** cells: HT2 in BMS "IL2-deprived"
    *** unaffected by: IL2 (10 min) [stim]
    *** source: 8397196-Fig-6
  *** Pik3rs[Ab] snaggedby[WB] rCdh1[GST] is undetectable
    *** cells: MDCK in BMS
    *** unaffected by: Egf (10 min) [stim]
    *** source: 11716761-Fig-2h
  *** Pik3rs[Ab] snaggedby[WB] rCdh1[GST] is undetectable
    *** cells: SCC12F in BMS "containing hydrocortisone"
    *** unaffected by: Egf (10 min) [stim]
    *** source: 11716761-Fig-2d
  *** Pik3rs[Ab] snaggedby[WB] rCtnnb1[GST] is detectable
    *** cells: HN5 in BMS
    *** source: 11716761-Fig-6a
  *** Pik3rs[Ab] snaggedby[WB] rCtnnb1[GST] is detectable
    *** cells: hSVKs in BMS "containing hydrocortisone"
    *** source: 11716761-Fig-6a
  *** Pik3rs[Ab] snaggedby[WB] rCtnnb1[GST] is detectable
    *** cells: MDCK in BMS
    *** source: 11716761-Fig-6a
  *** Pik3rs[Ab] snaggedby[WB] rCtnnb1[GST] is detectable
    *** cells: SCC12F in BMS "containing hydrocortisone"
    *** source: 11716761-Fig-6a
  *** Pik3rs[Ab]IP Yphos[pYAb] is increased itpo xLck(Y505F)"CA"
    *** cells: CTLL2 in BMS "IL2-deprived"
    *** inhibited by: xLck [substitution]
    *** source: 8397196-Fig-4
  *** Pik3rs[Ab]IP Yphos[pYAb] is increased itpo xLck(Y505F)"CA"
    *** cells: HT2 in BMS "IL2-deprived"
    *** inhibited by: xLck [substitution]
    *** source: 8397196-Fig-4
  *** xPik3rs[tAb] copptby[WB] Gab1[tAb] is detectable
    *** cells: HEK293T<xJak1> in BMS
    *** source: 9632795-Fig-2
  *** xPik3rs[tAb] copptby[WB] Shp2[tAb] is undetectable
    *** cells: HEK293T<xJak1> in BMS
    *** source: 9632795-Fig-2
*** Pin1--
  *** Pin1[Ab] boundto(Bax-gene)[ChIP] is detectable
    *** cells: SAOS2<Tp53~null><xTp53> in BMS
    *** does not req: xTp53 [omission]
    *** unaffected by: xTp53(S33A/S46A/T81A/S315A) [substitution]
    *** unaffected by: xTp53(S33A/S46A/T81A/S127A/T150A/S315A) [substitution]
    *** comment: xTp53 is phosed on S15 [phosAb] in all constructs
    *** source: 17906639-Fig-3c
  *** Pin1[Ab] boundto(Bax-gene)[ChIP] is detectable
    *** cells: SAOS2<Tp53~null><xTp53> in BMS "treated with Etoposide for 12 hr"
    *** reqs: xTp53 [omission]
    *** partially inhibited by: xTp53(S33A/S46A/T81A/S315A) [substitution]
    *** inhibited by: xTp53(S33A/S46A/T81A/S127A/T150A/S315A) [substitution]
    *** comment: xTp53 is phosed on S15 [phosAb] in all constructs
    *** source: 17906639-Fig-3c
  *** Pin1[Ab] boundto(Cdkn1a-gene)[ChIP] is detectable
    *** cells: H1299<Tp53~null><xTp53> in BMS
    *** partially inhibited by: xTp53(S33A/S46A/T81A/S315A) [substitution]
    *** inhibited by: xTp53(S33A/S46A/T81A/S127A/T150A/S315A) [substitution]
    *** source: 17906639-Fig-3b
  *** Pin1[Ab] boundto(Cdkn1a-gene)[ChIP] is detectable
    *** cells: SAOS2<Tp53~null><xTp53> in BMS
    *** reqs: xTp53 [omission]
    *** inhibited by: xTp53(S33A/S46A/T81A/S315A) [substitution]
    *** inhibited by: xTp53(S33A/S46A/T81A/S127A/T150A/S315A) [substitution]
    *** comment: xTp53 is phosed on S15 [phosAb] in all constructs
    *** source: 17906639-Fig-3c
  *** Pin1[Ab] boundto(Cdkn1a-gene)[ChIP] is detectable
    *** cells: SAOS2<Tp53~null><xTp53> in BMS "treated with Etoposide for 12 hr"
    *** reqs: xTp53 [omission]
    *** inhibited by: xTp53(S33A/S46A/T81A/S315A) [substitution]
    *** inhibited by: xTp53(S33A/S46A/T81A/S127A/T150A/S315A) [substitution]
    *** comment: xTp53 is phosed on S15 [phosAb] in all constructs
    *** source: 17906639-Fig-3c
  *** Pin1[Ab] copptby[WB] Myc[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 19131971-Fig-1b
  *** Pin1[Ab] copptby[WB] Rela[Ab] is detectable
    *** cells: HELA in BMS
    *** source: 14690596-Fig-3i
  *** xPin1[Ab] copptby[WB] Rela[Ab] is detectable
    *** cells: HELA in BMS
    *** source: 14690596-Fig-3i
  *** Pin1[Ab] copptby[WB] Sp1[Ab] is undetectable
    *** cells: HEK293 in BMS
    *** source: 19131971-Fig-1b
  *** Pin1[Ab] copptby[WB] Tp53[Ab] is detectable
    *** cells: U2OS in BMS "treated with Adriamycin"
    *** source: 12397361-Fig-1b
  *** Pin1[Ab] copptby[WB] xBraf(V600E)[tAb] is detectable
    *** cells: NIH3T3<xBraf(V600E)> in BMS
    *** inhibited by: xBraf [substitution]
    *** unaffected by: xBraf(G466A) [substitution]
    *** inhibited by: xBraf(D594G) [substitution]
    *** source: 19933846-Fig-7b
  *** Pin1[Ab] copptby[WB] xJun[Ab] is detectable
    *** cells: HELA<xJun> in BMS
    *** enhanced by: xHras(Q61L) [addition]
    *** unaffected by: xJnk?(mnr)"CA" [addition]
    *** source: 11432833-Fig-4g
  *** Pin1[Ab] copptby[WB] xJun[Ab] is detectable
    *** cells: MCF7 in BMS
    *** source: 11432833-Fig-4h
  *** Pin1[Ab] copptby[WB] xJun[Ab] is detectable
    *** cells: T47D in BMS
    *** source: 11432833-Fig-4h
  *** Pin1[Ab] copptby[WB] xMyc[Ab] is increased itpo xAxin1
    *** cells: HEK293<xMyc> in BMS
    *** source: 19131971-Fig-2e
  *** xPin1[XFP] locatedin(nucleus)[IHC] is detectable
    *** cells: HELA<xPin1> in BMS
    *** inhibited by: xPin1(W34A) [substitution]
    *** inhibited by: xPin1(K63A) [substitution]
    *** source: 11533658-Fig-7a
*** Pirh2--
  *** Pirh2-gene mRNA[RTPCR] is increased itao Cop1 [RNAi]
    *** cells: U2OS in BMS
    *** source: 15103385-Fig-3a
  *** Pirh2[Ab] prot-exp[WB] is increased itao Cop1 [RNAi]
    *** cells: U2OS in BMS
    *** source: 15989956-Fig-8a
  *** Pirh2[Ab] prot-exp[WB] is increased itao Huwe1 [RNAi]
    *** cells: U2OS in BMS
    *** source: 15989956-Fig-8a
  *** Pirh2[Ab] prot-exp[WB] is increased itao Mdm2 [RNAi]
    *** cells: U2OS in BMS
    *** source: 15989956-Fig-8a
  *** Pirh2[Ab] prot-exp[WB] is increased itpo xTp53
    *** cells: H1299<Tp53~null><xTp53> in BMS
    *** unaffected by: xTp53(K120R/K164R/K370R/K372R/K373R/K381R/K382R/K386R)"8KR" [substitution]
    *** source: 18485870-Fig-S10
*** Pkac--
  *** rPkac?[35S] boundby[WB] rIkba[GST] is detectable
    *** cells: none
    *** source: 9150141-Fig-2a
  *** rPkac?[35S] boundby[WB] rIkbb[GST] is detectable
    *** cells: none
    *** source: 9150141-Fig-2a
  *** xPkac?[tAb] copptby[WB] xIkba[Ab] is detectable
    *** cells: COS1<xRela> in BMS
    *** source: 9150141-Fig-2b
  *** xPkac?[tAb] copptby[WB] xIkbb[Ab] is detectable
    *** cells: COS1<xRela> in BMS
    *** source: 9150141-Fig-2b
  *** xPkac?[tAb] copptby[WB] xRela[Ab] is detectable
    *** cells: COS1<xIkba> in BMS
    *** source: 9150141-Fig-2b
  *** xPkac?[tAb] copptby[WB] xRela[Ab] is undetectable
    *** cells: COS1<xIkbb> in BMS
    *** source: 9150141-Fig-2b
  *** Pkacs[Ab] copptby[WB] Ikba[Ab] is detectable
    *** cells: 70Z3 in BMS
    *** source: 9150141-Fig-2e
  *** Pkacs[Ab] copptby[WB] Ikbb[Ab] is detectable
    *** cells: 70Z3 in BMS
    *** source: 9150141-Fig-2e
  *** Pkacs[Ab] copptby[WB] Pkars[Ab] is detectable
    *** cells: 70Z3 in BMS
    *** source: 9150141-Fig-2d
  *** Pkacs[Ab] copptby[WB] Rela[Ab] is detectable
    *** cells: 70Z3 in BMS
    *** source: 9150141-Fig-2c
  *** Pkacs[Ab] copptby[WB] Rela[Ab] is detectable
    *** cells: 70Z3 in BMS
    *** source: 9150141-Fig-2e
  *** Pkacs[Ab] copptby[WB] Rela[Ab] is detectable
    *** cells: JURKAT<Pten~null> in BMS
    *** source: 9150141-Fig-2c
  *** Pkacs[Ab] prot-exp[WB] is unchanged itao Pdpk1 [KO]
    *** cells: mESCs in BMLS
    *** source: 10801415-Fig-7b
  *** rPkar?[35S] boundby[WB] rIkba[GST] is undetectable
    *** cells: none
    *** source: 9150141-Fig-2a
  *** rPkar?[35S] boundby[WB] rIkbb[GST] is undetectable
    *** cells: none
    *** source: 9150141-Fig-2a
  *** rPkar?[35S] boundby[WB] rPkac?[GST] is detectable
    *** cells: none
    *** source: 9150141-Fig-3c
  *** Pkars[Ab] copptby[WB] Ikba[Ab] is undetectable
    *** cells: 70Z3 in BMS
    *** source: 9150141-Fig-2e
  *** Pkars[Ab] copptby[WB] Ikbb[Ab] is undetectable
    *** cells: 70Z3 in BMS
    *** source: 9150141-Fig-2e
  *** Pkars[Ab] copptby[WB] Rela[Ab] is undetectable
    *** cells: 70Z3 in BMS
    *** source: 9150141-Fig-2e
*** Pkca--
  *** rPkca[35S] boundby[WB] rIkk1[tAb] is detectable
    *** cells: none
    *** source: 10022904-Fig-1a
  *** rPkca[35S] boundby[WB] rIkk2[tAb] is detectable
    *** cells: none
    *** source: 10022904-Fig-1a
  *** Pkca[Ab] prot-exp[WB] is detectable
    *** cells: H197 in BMS
    *** source: 10330161-Fig-4a
  *** Pkca[Ab] prot-exp[WB] is detectable
    *** cells: mESCs in BMS
    *** partially reqs: Pdpk1 [KO]
    *** source: 11078882-Fig-1
  *** Pkca[Ab]IP IVKA(peptide)[32P-ATP] is detectable
    *** cells: HELA in BMS
    *** does not req: Raptor [RNAi]
    *** source: 15268862-Fig-4b
  *** Pkca[Ab]IP IVKA(peptide)[32P-ATP] is detectable
    *** cells: HELA in BMS
    *** partially reqs: Mtor [RNAi]
    *** source: 15268862-Fig-4b
  *** Pkca[Ab]IP IVKA(peptide)[32P-ATP] is detectable
    *** cells: HELA in BMS
    *** partially reqs: Rictor [RNAi]
    *** source: 15268862-Fig-4b
  *** Pkca[phosAb] phos(S657)[phosAb] is detectable
    *** cells: DROSOPHILAS2 in BMS
    *** does not req: Raptor [RNAi]
    *** source: 15268862-Fig-4c
  *** Pkca[phosAb] phos(S657)[phosAb] is detectable
    *** cells: DROSOPHILAS2 in BMS
    *** reqs: Mtor [RNAi]
    *** source: 15268862-Fig-4c
  *** Pkca[phosAb] phos(S657)[phosAb] is detectable
    *** cells: DROSOPHILAS2 in BMS
    *** reqs: Rictor [RNAi]
    *** source: 15268862-Fig-4c
  *** Pkca[phosAb] phos(S657)[phosAb] is detectable
    *** cells: HELA in BMS
    *** does not req: Raptor [RNAi]
    *** source: 15268862-Fig-4a
  *** Pkca[phosAb] phos(S657)[phosAb] is detectable
    *** cells: HELA in BMS
    *** reqs: Mtor [RNAi]
    *** source: 15268862-Fig-4a
  *** Pkca[phosAb] phos(S657)[phosAb] is detectable
    *** cells: HELA in BMS
    *** reqs: Rictor [RNAi]
    *** source: 15268862-Fig-4a
  *** Pkca[phosAb] phos(S657)[phosAb] is detectable
    *** cells: mEFs in BMS
    *** does not req: Ikke or Tbk1 [KO]
    *** source: 21464307-Fig-S2a
  *** xPkca[tAb] copptby[WB] xIkk1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 10022904-Fig-1c
  *** xPkca[tAb] copptby[WB] xIkk2[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 10022904-Fig-1a
  *** Pkcb[Ab] prot-exp[WB] is detectable
    *** cells: H197 in BMS
    *** source: 10330161-Fig-4a
*** Pkcb2--
  *** rPkcb2(mnr)"K8"[32P] phos[32P-ATP] is increased by xPdpk1[tAb]IP
    *** cells: none
    *** IPfrom: COS7<xPdpk1> in BMS
    *** unaffected by: Sphingosine [addition]
    *** source: 10995762-Fig-4
  *** xPkcb2[Ab] copptby[WB] xPdpk1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: Serum (20 min) [stim]
    *** source: 9889098-Fig-3a
  *** Pkcb2[Ab] prot-exp[WB] is detectable
    *** cells: mESCs in BMS
    *** partially reqs: Pdpk1 [KO]
    *** source: 11078882-Fig-1
  *** xPkcb2[phosAb] phos(T500)[phosAb] is detectable
    *** cells: COS7 in BMS
    *** unaffected by: xPdpk1 [addition]
    *** unaffected by: xPdpk1(K110N)"KD" [addition]
    *** source: 9889098-Fig-1a
*** Pkcd--
  *** Pkcd-gene mRNA[Northern] is detectable
    *** cells: mESCs in BMS
    *** partially reqs: Pdpk1 [KO]
    *** source: 11078882-Fig-2a
  *** Pkcd[Ab] infraction(cytoplasmic)[WB] is detectable
    *** cells: H197 in BMS
    *** source: 10330161-Fig-1b
  *** Pkcd[Ab] infraction(membrane)[WB] is detectable
    *** cells: H197 in BMS
    *** source: 10330161-Fig-4b
  *** Pkcd[Ab] prot-exp[WB] is detectable
    *** cells: H197 in BMS
    *** source: 10330161-Fig-4a
  *** Pkcd[Ab] prot-exp[WB] is detectable
    *** cells: mESCs in BMS
    *** partially reqs: Pdpk1 [KO]
    *** source: 11078882-Fig-1
  *** Pkcd[Ab] prot-exp[WB] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 10330161-Fig-6b
  *** Pkcd[Ab]IP infraction(PM2)[WB] is detectable
    *** cells: C3H10T12 in BMLS
    *** source: 11358964-Fig-2e
  *** xPkcd[tAb]IP phos[32P-ATP] is detectable
    *** cells: 32D in BMLS
    *** inhibited by: xPkcd(S645A) [substitution]
    *** source: 9305920-Fig-3
*** Pkce--
  *** rPkce[32P] IVKA(auto)[32P-ATP] is increased by (PS + PC)
    *** cells: none
    *** enhanced by: DAG [addition]
    *** inhibited by: PIP3 [addition]
    *** source: 11964154-Fig-4
  *** Pkce[Ab] prot-exp[WB] is detectable
    *** cells: H197 in BMS
    *** source: 10330161-Fig-4a
  *** Pkce[Ab] prot-exp[WB] is detectable
    *** cells: mESCs in BMS
    *** reqs: Pdpk1 [KO]
    *** source: 11078882-Fig-1
  *** Pkce[Ab]IP infraction(PM2)[WB] is detectable
    *** cells: C3H10T12 in BMLS
    *** source: 11358964-Fig-2e
  *** xPkce[Ab]IP IVKA(MBP)[32P-ATP] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xPkce(K437W) [substitution]
    *** unaffected by: xPkce(T566E) [substitution]
    *** unaffected by: xPkce(T710E) [substitution]
    *** source: 11964154-Fig-3a
  *** xPkce[Ab]IP phos(S729)[phosAb] is detectable
    *** cells: HEK293 in BMLS
    *** inhibited by: xPkce(T566A) [substitution]
    *** enhanced by: xPkce(myr)"CA" [substitution]
    *** source: 11964154-Fig-2b
  *** xPkce[Ab]IP phos(S729)[phosAb] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xPkce(K437W) [substitution]
    *** unaffected by: xPkce(T566E) [substitution]
    *** unaffected by: xPkce(T710E) [substitution]
    *** source: 11964154-Fig-3a
  *** xPkce[Ab]IP phos(T566)[phosAb] is detectable
    *** cells: HEK293 in BMLS
    *** inhibited by: xPkce(T566A) [substitution]
    *** enhanced by: xPkce(myr)"CA" [substitution]
    *** source: 11964154-Fig-2b
  *** xPkce[phosAb] phos(S346)[phosAb] is increased itpo xMyd88
    *** cells: HEK293<xTLR4><xMd2><xCd14> in BMS
    *** source: 18458086-Fig-4e,4f
  *** Pkce[phosAb] phos(S657)[phosAb] is detectable
    *** cells: HELA in BMS
    *** does not req: Mtor [RNAi]
    *** source: 15268862-Fig-S2b
  *** Pkce[phosAb] phos(S657)[phosAb] is detectable
    *** cells: HELA in BMS
    *** does not req: Raptor [RNAi]
    *** source: 15268862-Fig-S2b
  *** Pkce[phosAb] phos(S657)[phosAb] is detectable
    *** cells: HELA in BMS
    *** does not req: Rictor [RNAi]
    *** source: 15268862-Fig-S2b
  *** Pkcg[Ab] prot-exp[WB] is detectable
    *** cells: H197 in BMS
    *** source: 10330161-Fig-4a
  *** Pkcg[Ab] prot-exp[WB] is detectable
    *** cells: mESCs in BMS
    *** partially reqs: Pdpk1 [KO]
    *** source: 11078882-Fig-1
  *** Pkch[Ab] prot-exp[WB] is undetectable
    *** cells: H197 in BMS
    *** source: 10330161-Fig-4a
*** Pkci--
  *** rPkci[35S] boundby[WB] rIkk1[tAb] is undetectable
    *** cells: none
    *** source: 10022904-Fig-1a
  *** rPkci[35S] boundby[WB] rIkk2[tAb] is undetectable
    *** cells: none
    *** source: 10022904-Fig-1a
  *** Pkci[Ab] prot-exp[WB] is detectable
    *** cells: H197 in BMS
    *** source: 10330161-Fig-4a
  *** xPkci[Ab]IP IVKA(peptide)[32P-ATP] is increased itpo xHras(Q61L)"CA"
    *** cells: COS1 in BMS
    *** inhibited by: xRac1(T17N)"DN" [addition]
    *** source: 9971737-Fig-7a
  *** xPkci[tAb] copptby[WB] xIkk1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 10022904-Fig-1b
  *** xPkci[tAb] copptby[WB] xIkk2[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 10022904-Fig-1a
  *** Pkcq[Ab] prot-exp[WB] is undetectable
    *** cells: H197 in BMS
    *** source: 10330161-Fig-4a
*** Pkcs--
*** Pkcz--
  *** rPkcz[35S] boundby[WB] rIkk1[tAb] is detectable
    *** cells: none
    *** source: 10022904-Fig-1a
  *** rPkcz[35S] boundby[WB] rIkk2[tAb] is detectable
    *** cells: none
    *** source: 10022904-Fig-1a
  *** xPkcz[Ab] boundby[FarWestern] rYwhaq[GST] is detectable
    *** cells: COS7 in BMS
    *** source: 10620507-Fig-3
  *** rPkcz[Ab] boundby[WB] rYwhaq[GST] is detectable
    *** cells: none
    *** comment: binding is prevented by treatment of rPkcz with phosphatase
    *** source: 10620507-Fig-4
  *** Pkcz[Ab] copptby[WB] xPak1[tAb] is undetectable
    *** cells: NIH3T3 in BMLS
    *** source: 9768361-Fig-5
  *** Pkcz[Ab] copptby[WB] xRac1[tAb] is undetectable
    *** cells: NIH3T3 in BMLS
    *** source: 9768361-Fig-5
  *** xPkcz[Ab] copptby[WB] xRaf1[Ab] is detectable
    *** cells: COS7 in BMS
    *** enhanced by: xPkcz(K281W)"KD" [substitution]
    *** source: 10620507-Fig-5
  *** xPkcz[Ab] copptby[WB] xRaf1[Ab] is detectable
    *** cells: COS7 in BMS
    *** enhanced by: xYwhab [addition]
    *** source: 10620507-Fig-2
  *** xPkcz[Ab] copptby[WB] xRaf1[Ab] is detectable
    *** cells: COS7 in BMS
    *** enhanced by: xYwhag [addition]
    *** source: 10620507-Fig-2
  *** xPkcz[Ab] copptby[WB] xRaf1[Ab] is detectable
    *** cells: COS7 in BMS
    *** enhanced by: xYwhaq [addition]
    *** source: 10620507-Fig-2
  *** xPkcz[Ab] copptby[WB] xRaf1[Ab] is detectable
    *** cells: COS7 in BMS
    *** unaffected by: xPkcz(S186A) [substitution]
    *** source: 10620507-Fig-4
  *** xPkcz[Ab] copptby[WB] xRaf1[Ab] is detectable
    *** cells: COS7 in BMS
    *** unaffected by: xYwhah [addition]
    *** source: 10620507-Fig-2
  *** xPkcz[Ab] copptby[WB] xRaf1[Ab] is detectable
    *** cells: COS7 in BMS
    *** unaffected by: xYwhaz [addition]
    *** source: 10620507-Fig-2
  *** xPkcz[Ab] copptby[WB] xRaf1[Ab] is increased itpo xYwhab
    *** cells: COS7 in BMS
    *** enhanced by: xYwhab(S130A) [substitution]
    *** enhanced by: xYwhab(T141A) [substitution]
    *** source: 10620507-Fig-8
  *** xPkcz[Ab] copptby[WB] xRaf1[Ab] is increased itpo xYwhab
    *** cells: COS7 in BMS
    *** inhibited by: xPkcz(S186A) [substitution]
    *** source: 10620507-Fig-4
  *** xPkcz[Ab] copptby[WB] xRaf1[Ab] is increased itpo xYwhab
    *** cells: COS7 in BMS
    *** source: 10620507-Fig-5
  *** xPkcz[Ab] copptby[WB] Ywhas[Ab] is detectable
    *** cells: COS7 in BMS
    *** enhanced by: xPkcz(K281W)"KD" [substitution]
    *** source: 10620507-Fig-7
  *** xPkcz[Ab] copptby[WB] Ywhas[Ab] is detectable
    *** cells: COS7 in BMS
    *** inhibited by: xPkcz(S186A) [substitution]
    *** source: 10620507-Fig-4
  *** Pkcz[Ab] prot-exp[WB] is detectable
    *** cells: H197 in BMS
    *** source: 10330161-Fig-4a
  *** Pkcz[Ab] prot-exp[WB] is detectable
    *** cells: mESCs in BMS
    *** does not req: Pdpk1 [KO]
    *** source: 11078882-Fig-1
  *** Pkcz[Ab] prot-exp[WB] is detectable
    *** cells: mESCs in BMS "protamine-agarose binding fraction"
    *** does not req: Pdpk1 [KO]
    *** source: 11078882-Fig-3b
  *** xPkcz[Ab]IP IVKA(MBP)[32P-ATP] is increased itpo xHras(Q61L)"CA"
    *** cells: COS1 in BMS
    *** source: 9971737-Fig-7b
  *** xPkcz[Ab]IP IVKA(MBP)[32P-ATP] is increased itpo xRac1(G12V)"CA"
    *** cells: COS1 in BMS
    *** source: 9971737-Fig-7b
  *** xPkcz[phosAb] phos(T410)[phosAb] is detectable
    *** cells: HEK293<xPkcz> in BMS
    *** inhibited by: xPkcz(T410A) [substitution]
    *** source: 11078882-Fig-3a
  *** xPkcz[phosAb] phos(T560)[phosAb] is detectable
    *** cells: HEK293 in BMLS
    *** inhibited by: LY294002 [addition]
    *** source: 9748166-Fig-3d
  *** xPkcz[phosAb] phos(T816)[phosAb] is detectable
    *** cells: HEK293<xPkcz> in BMS
    *** inhibited by: xPkcz(T410A) [substitution]
    *** source: 11078882-Fig-3a
  *** Pkcz[phosAb] phos(T816)[phosAb] is detectable
    *** cells: mESCs in BMS "protamine-agarose binding fraction"
    *** reqs: Pdpk1 [KO]
    *** source: 11078882-Fig-3b
  *** xPkcz[tAb] copptby[WB] xIkk1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 10022904-Fig-1c
  *** xPkcz[tAb] copptby[WB] xIkk2[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 10022904-Fig-1b
  *** xPkcz[tAb] copptby[WB] xRipk1[tAb] is increased itpo xSqstm1
    *** cells: HEK293 in BMS
    *** source: 10356400-Fig-7a
  *** xPkcz[tAb] copptby[WB] xRipk1[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 10356400-Fig-3a,3c
  *** xPkcz[tAb] copptby[WB] xSqstm1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: xTraf6 [addition]
    *** source: 10747026-Fig-5
  *** xPkcz[tAb] copptby[WB] xTraf6[tAb] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: xTraf6 [addition]
    *** source: 10747026-Fig-5
  *** xPkcz[tAb]IP phos(T410)[phosAb] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xPkcz(T410A) [substitution]
    *** source: 9768361-Fig-3a
*** Pkm2--
  *** rPkm2[MS] cleavage[WB] is increased by rCasp1
    *** cells: none
    *** source: 17959595(D)
  *** rPkm2[MS] cleavage[WB] is increased by rCasp3
    *** cells: none
    *** source: 17959595(D)
*** Pkn1--
  *** Pkn1-gene mRNA[Northern] is detectable
    *** cells: mESCs in BMS
    *** does not req: Pdpk1 [KO]
    *** source: 11078882-Fig-2a
  *** pPkn1[32P] IVKA(auto)[32P-ATP] is unchanged by rHras{GTPgS}
    *** cells: none
    *** unaffected by: rHras [substitution]
    *** source: 8571127-Fig-3a
  *** pPkn1[32P] IVKA(auto)[32P-ATP] is unchanged by rRac1{GTPgS}
    *** cells: none
    *** unaffected by: rRac1 [substitution]
    *** source: 8571127-Fig-3a
  *** Pkn1[Ab] prot-exp[WB] is detectable
    *** cells: mESCs in BMS "protamine-agarose binding fraction"
    *** reqs: Pdpk1 [KO]
    *** source: 11078882-Fig-1
  *** rPkn1[tAb] boundby[WB] rHras{GTPgS}[GST] is undetectable
    *** cells: none
    *** unaffected by: rHras [substitution]
    *** source: 8571127-Fig-4a
  *** rPkn1[tAb] boundby[WB] rRac1{GTPgS}[GST] is undetectable
    *** cells: none
    *** unaffected by: rRac1 [substitution]
    *** source: 8571127-Fig-4a
  *** Pkn2[Ab] prot-exp[WB] is detectable
    *** cells: mESCs in BMS
    *** does not req: Pdpk1 [KO]
    *** source: 11078882-Fig-1
*** Pkr--
  *** xPkr(K271A)[tAb] copptby[WB] xTirap[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 11526399(D)
  *** xPkr[Ab] copptby[WB] Ikk1[Ab] is detectable
    *** cells: HEK293T<xPkr> in BMS
    *** source: 10648614-Fig-7a
  *** xPkr[tAb] copptby[WB] xTraf3[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 16306936-Fig-4a
*** Pla2g4a--
  *** rPla2g4a[32P] phos[32P-ATP] is unchanged by rP38a
    *** cells: none
    *** source: 7535770-Fig-1a
  *** rPlcb1 boundby[SPR] rCdc42{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rCdc42{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb1 boundby[SPR] rRac1{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRac1{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb1 boundby[SPR] rRac2{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRac2{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb1 boundby[SPR] rRac3{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRac3{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb1 boundby[SPR] rRhoa{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRhoa{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb1 boundby[SPR] rRhob{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRhob{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb1 boundby[SPR] rRhobtb2{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRhobtb2{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb1 boundby[SPR] rRhoc{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRhoc{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb1 boundby[SPR] rRhod{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRhod{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb1 boundby[SPR] rRhof{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRhof{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb1 boundby[SPR] rRhog{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRhog{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb1 boundby[SPR] rRhoj{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRhoj{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb1 boundby[SPR] rRhoq{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRhoq{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb1 boundby[SPR] rRnd1{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRnd1{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb1 boundby[SPR] rRnd2{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRnd2{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb1 boundby[SPR] rRnd3{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRnd3{GDP} [substitution]
    *** source: 12657629-Fig-1f
*** Plcb1--
  *** rPlcb2 boundby[SPR] rCdc42{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rCdc42{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb2 boundby[SPR] rRac1{GTPgS}[RU] is detectable
    *** cells: none
    *** inhibited by: rRac1{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb2 boundby[SPR] rRhoa{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRhoa{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb2 boundby[SPR] rRhob{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRhob{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb2 boundby[SPR] rRhobtb2{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRhobtb2{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb2 boundby[SPR] rRhoc{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRhoc{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb2 boundby[SPR] rRhod{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRhod{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb2 boundby[SPR] rRhof{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRhof{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb2 boundby[SPR] rRhog{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRhog{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb2 boundby[SPR] rRhoj{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRhoj{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb2 boundby[SPR] rRhoq{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRhoq{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb2 boundby[SPR] rRnd1{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRnd1{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb2 boundby[SPR] rRnd2{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRnd2{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb2 boundby[SPR] rRnd3{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRnd3{GDP} [substitution]
    *** source: 12657629-Fig-1f
*** Plcb2--
  *** xPlcb2[Ab] snaggedby[WB] rHras{GTPgS}[GST] is undetectable
    *** cells: COS7 in BMS
    *** unaffected by: rHras{GDP} [substitution]
    *** source: 12900402-Fig-5
  *** xPlcb2[Ab] snaggedby[WB] rRac1{GTPgS}[GST] is detectable
    *** cells: COS7 in BMS
    *** inhibited by: rRac1{GDP} [substitution]
    *** source: 12900402-Fig-5
  *** xPlcb2[Ab] snaggedby[WB] rRhoa{GTPgS}[GST] is undetectable
    *** cells: COS7 in BMS
    *** unaffected by: rRhoa{GDP} [substitution]
    *** source: 12900402-Fig-5
  *** rPlcb3 boundby[SPR] rCdc42{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rCdc42{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb3 boundby[SPR] rRhoa{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRhoa{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb3 boundby[SPR] rRhob{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRhob{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb3 boundby[SPR] rRhobtb2{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRhobtb2{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb3 boundby[SPR] rRhoc{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRhoc{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb3 boundby[SPR] rRhod{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRhod{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb3 boundby[SPR] rRhof{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRhof{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb3 boundby[SPR] rRhog{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRhog{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb3 boundby[SPR] rRhoj{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRhoj{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb3 boundby[SPR] rRhoq{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRhoq{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb3 boundby[SPR] rRnd1{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRnd1{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb3 boundby[SPR] rRnd2{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRnd2{GDP} [substitution]
    *** source: 12657629-Fig-1f
  *** rPlcb3 boundby[SPR] rRnd3{GTPgS}[RU] is undetectable
    *** cells: none
    *** unaffected by: rRnd3{GDP} [substitution]
    *** source: 12657629-Fig-1f
*** Plcb3--
*** Plce1--
  *** xPlce1(1382-2303)[tAb] copptby[WB] xHras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xHras(G12V/D38A) [substitution]
    *** inhibited by: xHras(G12V/T35S) [substitution]
    *** inhibited by: xHras(G12V/E37G) [substitution]
    *** inhibited by: xHras(G12V/Y40C) [substitution]
    *** inhibited by: xHras(G12V/D38E) [substitution]
    *** source: 15143186-Fig-6
  *** xPlce1(1382-2303)[tAb] copptby[WB] xKras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xPlce1(1382-2303)[tAb] copptby[WB] xMras(Q71L)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xPlce1(1382-2303)[tAb] copptby[WB] xNras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xPlce1(1382-2303)[tAb] copptby[WB] xRap1a(G12V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xPlce1(1382-2303)[tAb] copptby[WB] xRap2a(G12V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xPlce1(1382-2303)[tAb] copptby[WB] xRras(G38V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xPlce1(1382-2303)[tAb] copptby[WB] xRras2(G23V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xPlce1[tAb] locatedin(cellmembrane)[IHC] is increased itpo xRap2b(G12V)"CA"
    *** cells: HEK293 in BMLS
    *** source: 15143162-Fig-3a
*** Plcg1--
  *** rPlcg1[Ab] boundby[WB] rPld2[Ab] is decreased by rStxbp1
    *** cells: none
    *** source: 14744865-Fig-S2
  *** Plcg1[Ab] copptby[WB] xPld2[Ab] is detectable
    *** cells: COS7<xPld2> in BMS
    *** source: 12646582-Fig-1a
  *** Plcg1[Ab]IP Yphos[pYAb] is detectable
    *** cells: mEFs<Src~null><Yes1~null><Fyn~null><xSrc> in BMLS
    *** reqs: xSrc [omission]
    *** source: 14967142-Fig-2c
  *** xPlcg1[tAb] copptby[WB] Akts[Ab] is detectable
    *** cells: COS7<xPlcg1> in BMLS
    *** unaffected by: xPlcg1(mnr)"delPH" [substitution]
    *** inhibited by: xPlcg1(mnr)"delSH3" [substitution]
    *** source: 16525023-Fig-3b
  *** xPlcg1[tAb] copptby[WB] Akts[Ab] is detectable
    *** cells: COS7<xPlcg1> in BMLS
    *** unaffected by: xPlcg1(Y771F) [substitution]
    *** inhibited by: xPlcg1(Y783F) [substitution]
    *** inhibited by: xPlcg1(Y771F/Y783F) [substitution]
    *** source: 16525023-Fig-5
  *** xPlcg1[tAb] copptby[WB] xPld2[Ab] is detectable
    *** cells: COS7<xPlcg1><xPld2> in BMS
    *** inhibited by: xPlcg1(mnr)"delSH2" [substitution]
    *** source: 12646582-Fig-3d
*** Plcgs--
  *** Plcgs[Ab] copptby[WB] Git1[Ab] is detectable
    *** cells: rVSMCs in BMLS
    *** unaffected by: AngII (1 min) [stim]
    *** source: 14523024-Fig-1b
  *** Plcgs[Ab] copptby[WB] xTrka[Ab] is detectable
    *** cells: HEK293<xTrka> in BMS
    *** inhibited by: xTrka(Y791F) [substitution]
    *** source: 11418861-Fig-5a
  *** Plcgs[Ab] copptby[WB] xTrpv1[Ab] is undetectable
    *** cells: HEK293<xTrpv1> in BMS
    *** source: 11418861-Fig-5a
*** Pld1--
  *** xPld1[tAb] snaggedby[WB] rCdc42(Q61L)"CA"[GST] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-2
  *** xPld1[tAb] snaggedby[WB] rRac1(Q61L)"CA"[GST] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-2
  *** xPld1[tAb] snaggedby[WB] rRhoa(Q63L)"CA"[GST] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-2
  *** xPld1[tAb] snaggedby[WB] rRhog(Q61L)"CA"[GST] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-2
  *** xPld1[tAb] snaggedby[WB] rRhog[GST] is undetectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-2
  *** xPld2[Ab] locatedin(cellmembrane)[IHC] is detectable
    *** cells: COS7<xPld2> in BMLS
    *** source: 14744865-Fig-8b
  *** Plds[Ab] copptby[WB] Plcg1[Ab] is detectable
    *** cells: COS7 in BMS
    *** source: 12646582-Fig-1a
*** Plscr1--
  *** Plscr1[Ab] colocwith[IHC] EgfR[Ab] is detectable
    *** cells: KB in BMLS
    *** source: 12009895(D)
  *** Pmaip1-gene mRNA[RTPCR] is detectable
    *** cells: mEFs in BMS "treated with Adriamycin for 6 hr"
    *** unaffected by: kTp53(S18A) [knockin] 
    *** unaffected by: kTp53(S18A/S23A) [knockin] 
    *** source: 16757976-Fig-2a
  *** Pmaip1-gene mRNA[RTPCR] is detectable
    *** cells: mEFs in BMS "treated with Adriamycin for 12 hr"
    *** inhibited by: kTp53(S18A) [knockin] 
    *** inhibited by: kTp53(S18A/S23A) [knockin] 
    *** source: 16757976-Fig-2a
  *** Pmaip1-gene mRNA[RTPCR] is detectable
    *** cells: mThyCs in BMS "treated with IR for 18 hr"
    *** inhibited by: kTp53(S18A) [knockin] 
    *** inhibited by: kTp53(S18A/S23A) [knockin] 
    *** reqs: Tp53 [KO]
    *** source: 16757976-Fig-4b
  *** Pmaip1-gene mRNA[RTPCR] is detectable-but unchanged itpo xTp53
    *** cells: H1299<Tp53~null> in BMS
    *** unaffected by: xTp53(S46A) [substitution]
    *** unaffected by: xTp53(del(46-46)) [substitution]
    *** unaffected by: xTp53(S121F) [substitution]
    *** source: 11030628-Fig-8b
  *** Pmaip1-gene mRNA[RTPCR] is unchanged itpo xE4f1
    *** cells: U2OS in BMS
    *** unaffected by: xE4f1(del(41-85)) [substitution]
    *** source: 17110336-Fig-5a
*** Pml--
  *** rPml[35S] boundby[WB] rUbe2i[GST] is detectable
    *** cells: none
    *** source: 15210726-Fig-1b
  *** Pml[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: mEFs in BMS
    *** source: 15356634-Fig-S1d
  *** Pml[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: U2OS in BMS
    *** source: 11740489-Fig-1
*** Pmlc--
  *** Pmlc[Ab] infraction(cytoplasmic)[WB] is undetectable
    *** cells: mEFs in BMS
    *** source: 15356634-Fig-S1e
  *** Pmlc[Ab] infraction(nuclear)[WB] is undetectable
    *** cells: mEFs in BMS
    *** source: 15356634-Fig-S1e
  *** xPmlc[tAb] copptby[WB] xSmad3[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15356634-Fig-2f
  *** xPmlc[tAb] copptby[WB] xSmad3[tAb] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: Tgfb1 (1 hr) [stim]
    *** source: 15356634-Fig-2a
  *** xPmlc[tAb] locatedin(cytoplasm)[IHC] is detectable
    *** cells: mEFs<Pml~null> in BMS
    *** source: 15356634-Fig-S1d
  *** Pol2[Ab] snaggedby[WB] rMyc[GST] is undetectable
    *** cells: HELA in BMS "nuclear-extracts"
    *** source: 12660246-Fig-2a
  *** rPolr2a(mnr)"CTD"[32P] phos[32P-ATP] is increased by Abl1[Ab]IP
    *** cells: none
    *** IPfrom: mEFs in BMS "treated with IR for 1 hr"
    *** source: 9168116-Fig-1a
  *** rPolr2a(mnr)"CTD"[32P] phos[32P-ATP] is unchanged by xAtm(2711-2962)[tAb]IP
    *** cells: none
    *** IPfrom: mEFs<Abl1~null><xAbl1><xAtm(2711-2962)> in BMS
    *** source: 9168116-Fig-2c
  *** Polr2a[Ab] snaggedby[WB] rElk1(307-428){phos}[Gal4-DBD-G5TATA] is detectable
    *** cells: mESCs in BMS "nuclear extracts"
    *** inhibited by: rElk1(307-428) [substitution]
    *** source: 14506297-Fig-3
  *** Polr2a[Ab] snaggedby[WB] rElk1(307-428){phos}[Gal4-DBD-G5TATA] is detectable
    *** cells: mESCs in BMS "nuclear extracts"
    *** reqs: Med23 [KO]
    *** source: 14506297-Fig-3
*** Posh--
  *** Posh[Ab] copptby[WB] Jip1[Ab] is detectable
    *** cells: PC12 in BMS "neuronally differentiated"
    *** enhanced by: Camptothecin [addition]
    *** source: 16571722-Fig-2b
  *** Posh[Ab] copptby[WB] Siah1[Ab] is detectable
    *** cells: HEK293 in BMS "treated with Camptothecin"
    *** source: 16230351-Fig-1a
  *** xPosh[tAb] copptby[WB] xJip1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 16571722-Fig-1b
  *** xPosh[tAb] copptby[WB] xJip2[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 16571722-Fig-1b
  *** xPosh[tAb] copptby[WB] xJip3[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 16571722-Fig-1b
  *** xPosh[tAb] copptby[WB] xJnk1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12514131-Fig-4c
  *** xPosh[tAb] copptby[WB] xJnk2[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12514131-Fig-4c
  *** xPosh[tAb] copptby[WB] xMkk4[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12514131-Fig-4c
  *** xPosh[tAb] copptby[WB] xMkk7[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12514131-Fig-4c
  *** xPosh[tAb] copptby[WB] xMlk3[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12514131-Fig-3c
  *** xPosh[tAb] copptby[WB] xSiah1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 16230351-Fig-1a
*** Pou2f1--
  *** Pou2f1[Ab] boundto(A2m-gene)[ChIP] is detectable
    *** cells: H35 in BMS
    *** unaffected by: Dexamethasone [addition]
    *** unaffected by: IL6 (30 min) [stim]
    *** source: 14522952-Fig-4b
*** PP2a--
  *** pPP2a[32P] phos[32P-ATP] is increased by Mtor[Ab]IP
    *** cells: none
    *** source: 10200280-Fig-4a
  *** PP2a[Ab] copptby[WB] S6k1[Ab] is detectable
    *** cells: JURKATT in BMS
    *** unaffected by: Rapamycin [addition]
    *** source: 10200280-Fig-3a
  *** PP2a[Ab] copptby[WB] xAxin1[tAb] is undetectable
    *** cells: HEK293<xAxin1> in BMS
    *** source: 11487578-Fig-6a
  *** Ppard-gene mRNA[Northern] is increased itpo xPin1
    *** cells: MCF7 in BMS
    *** source: 11533658-Fig-1b
  *** Pparg-gene mRNA[RTPCR] is detectable
    *** cells: mSpCD4TCs in BMS
    *** source: 15187132-Fig-1
  *** Pparg-gene mRNA[RTPCR] is detectable
    *** cells: mSpCD8TCs in BMS
    *** source: 15187132-Fig-1
  *** Pparg[Ab] prot-exp[WB] is detectable
    *** cells: mPECs in BMS
    *** source: 10432118-Fig-1a
  *** Pparg[Ab] prot-exp[WB] is undetectable
    *** cells: hPBMCs in BMS
    *** source: 10432118-Fig-1b
  *** Pparg[Ab] prot-exp[WB] is undetectable
    *** cells: mRPECs in BMS
    *** source: 10432118-Fig-1a
  *** rPpp1ca IVPPaseAct(peptide)[FRET] is decreased by Ppp1r14d[Ab]IP
    *** cells: none
    *** IPfrom: NotReported in BMS
    *** comment: enhanced by treatment of cells with AngII for tnr
    *** comment: enhanced by treatment of cells with PMA for tnr
    *** source: 23720309-Fig-4c
  *** Ppp1ca[Ab] copptby[WB] xPpp1r14d[tAb] is detectable
    *** cells: JURKAT<xPpp1r14d> in BMS "treated with PMA for tnr"
    *** source: 23720309-Fig-4a
*** Ppp1cb--
  *** Ppp1cb[Ab] copptby[WB] xPpp1r14d[tAb] is undetectable
    *** cells: JURKAT<xPpp1r14d> in BMS "treated with PMA for tnr"
    *** source: 23720309-Fig-4a
  *** Ppp1cb[MS] copptby[WB] xMras(H81L)"CA"[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 16630891-Fig-1a
  *** Ppp1cc[Ab] copptby[WB] xPpp1r14d[tAb] is undetectable
    *** cells: JURKAT<xPpp1r14d> in BMS "treated with PMA for tnr"
    *** source: 23720309-Fig-4a
  *** Ppp1cc[MS] copptby[WB] xMras(H81L)"CA"[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 16630891-Fig-1a
*** Ppp1cs--
  *** Ppp1cs[Ab] copptby[WB] xHras(G12V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 16630891-Fig-1b
  *** Ppp1cs[Ab] copptby[WB] xHras[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 16630891-Fig-1b
  *** Ppp1cs[Ab] copptby[WB] xKras(G12V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 16630891-Fig-1b
  *** Ppp1cs[Ab] copptby[WB] xKras[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 16630891-Fig-1b
  *** Ppp1cs[Ab] copptby[WB] xNras(G12V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 16630891-Fig-1b,1f
  *** Ppp1cs[Ab] copptby[WB] xNras(G12V)"CA"[tAb] is undetectable
    *** cells: HEK293T<xRaf1> in BMS
    *** source: 16630891-Fig-3b
  *** Ppp1cs[Ab] copptby[WB] xNras[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 16630891-Fig-1b,1f
  *** Ppp1cs[Ab] copptby[WB] xRap1a(G12V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 16630891-Fig-1b
  *** Ppp1cs[Ab] copptby[WB] xRras(G38V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 16630891-Fig-1b
  *** Ppp1cs[Ab] copptby[WB] xRras[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 16630891-Fig-1b
  *** Ppp1cs[Ab] copptby[WB] xRras2(G13V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 16630891-Fig-1b
  *** Ppp1cs[Ab] copptby[WB] xRras2[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 16630891-Fig-1b
*** Ppp1r9b--
  *** Ppp1r9b[Ab] copptby[WB] Tiam1[Ab] is detectable
    *** cells: COS7 in BMS
    *** source: 12531897(D)
  *** xPpp1r9b[Ab] copptby[WB] xRasGrf1[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 12531897(D)
  *** xPpp1r9b[Ab] copptby[WB] xS6k1[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 12531897(D)
  *** xPpp1r9b[Ab] copptby[WB] xTiam1[Ab] is detectable
    *** cells: COS7 in BMS
    *** source: 12531897(D)
*** Ppp1r12a--
  *** rPpp1r12a[Ab] boundby[WB] rRhoa{GTPgS}[GST] is detectable
    *** cells: none
    *** inhibited by: rRhoa{GDP} [substitution]
    *** inhibited by: rRhoa(T37A){GTPgS} [substitution]
    *** source: 8662509-Fig-2a
*** Ppp2c?--
  *** rPpp2c?[Ab] boundby[WB] rRaf1[Ab] is detectable
    *** cells: none
    *** source: 10801873-Fig-4c
  *** xPpp2c?[Ab] copptby[WB] xPpp2r1?[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 10801873-Fig-4a
  *** xPpp2c?[tAb] copptby[WB] xIkk1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 14585847-Fig-1c
  *** xPpp2c?[tAb] copptby[WB] xIkk2[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 14585847-Fig-1c
  *** xPpp2c?[tAb] copptby[WB] xNemo[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 14585847-Fig-1c
  *** rPpp2ca[Ab] boundby[WB] xAxin1[MalBP] is detectable
    *** cells: none
    *** inhibited by: rAxin1(1-353) [substitution]
    *** unaffected by: rAxin1(298-506) [substitution]
    *** unaffected by: rAxin1(508-832) [substitution]
    *** source: 10698523-Fig-5d
  *** Ppp2ca[Ab] copptby[WB] Myc[Ab] is detectable
    *** cells: HEK293 in BMLS
    *** source: 16537924-Fig-4d
  *** Ppp2ca[Ab] copptby[WB] Myc[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 19131971-Fig-1b
  *** Ppp2ca[Ab] copptby[WB] Sp1[Ab] is undetectable
    *** cells: HEK293 in BMS
    *** source: 19131971-Fig-1b
  *** Ppp2ca[Ab] copptby[WB] xAxin1[tAb] is detectable
    *** cells: COS<xAxin1> in BMS
    *** inhibited by: xAxin1(1-353) [substitution]
    *** unaffected by: xAxin1(298-506) [substitution]
    *** unaffected by: xAxin1(508-832) [substitution]
    *** source: 10698523-Fig-5b
  *** Ppp2ca[Ab] copptby[WB] xAxin1[tAb] is detectable
    *** cells: COS<xAxin1> in BMS
    *** source: 10698523-Fig-5a
  *** Ppp2ca[Ab] copptby[WB] xAxin1[tAb] is detectable
    *** cells: HEK293<xAxin1><xMyc> in BMS
    *** inhibited by: xAxin1(1-594)"Ex2-6" [substitution]
    *** inhibited by: xAxin1(1-651)"Ex2-7" [substitution]
    *** unaffected by: xAxin1(1-728)"Ex2-8" [substitution]
    *** unaffected by: xAxin1(1-764)"Ex2-9" [substitution]
    *** source: 19131971-Fig-6c
  *** Ppp2ca[Ab] copptby[WB] xAxin1[tAb] is detectable
    *** cells: HEK293<xAxin1><xMyc> in BMS
    *** inhibited by: xAxin1(1-594)"Ex2-6" [substitution]
    *** unaffected by: xAxin1(595-862)"Ex6-11" [substitution]
    *** inhibited by: xAxin1(del(340-764))"delEx4-9" [substitution]
    *** source: 19131971-Fig-6b
  *** Ppp2ca[Ab] copptby[WB] xAxin1[tAb] is detectable
    *** cells: HEK293<xAxin1><xMyc> in BMS
    *** source: 19131971-Fig-1a
  *** Ppp2ca[Ab] copptby[WB] xAxin1[tAb] is detectable
    *** cells: HEK293<xAxin1><xMyc> in BMS
    *** unaffected by: xAxin1(del(729-764))"isoform2" [substitution]
    *** partially inhibited by: xAxin1(del(652-764))"delEx8-9" [substitution]
    *** source: 19131971-Fig-6e
  *** Ppp2ca[Ab] copptby[WB] xMyc[Ab] is detectable
    *** cells: HEK293<xAxin1><xMyc> in BMS
    *** inhibited by: xMyc(mnr)"delTAD" [substitution]
    *** source: 19131971-Fig-5a
  *** Ppp2ca[Ab] copptby[WB] xMyc[Ab] is detectable
    *** cells: HEK293<xMyc> in BMS
    *** partially reqs: Axin1 [RNAi]
    *** source: 19131971-Fig-2d
  *** Ppp2ca[Ab] copptby[WB] xMyc[Ab] is increased itpo xAxin1
    *** cells: HEK293<xMyc> in BMS
    *** source: 19131971-Fig-1e
  *** Ppp2ca[Ab] copptby[WB] xMyc[tAb] is detectable
    *** cells: HEK293<xPpp2r5a><xMyc> in BMLS
    *** inhibited by: xMyc(mnr)"delTAD" [substitution]
    *** source: 16537924-Fig-5a
  *** Ppp2ca[Ab] copptby[WB] xPpp2r5a[tAb] is detectable
    *** cells: HEK293<xMyc> in BMLS
    *** source: 16537924-Fig-4c
  *** Ppp2ca[Ab] copptby[WB] xPpp2r5b[tAb] is detectable
    *** cells: HEK293<xMyc> in BMLS
    *** source: 16537924-Fig-4c
  *** Ppp2ca[Ab] copptby[WB] xPpp2r5c1[tAb] is detectable
    *** cells: HEK293<xMyc> in BMLS
    *** source: 16537924-Fig-4c
  *** Ppp2ca[Ab] copptby[WB] xPpp2r5c3[tAb] is detectable
    *** cells: HEK293<xMyc> in BMLS
    *** source: 16537924-Fig-4c
  *** Ppp2ca[Ab] copptby[WB] xPpp2r5d[tAb] is detectable
    *** cells: HEK293<xMyc> in BMLS
    *** source: 16537924-Fig-4c
  *** Ppp2ca[Ab] copptby[WB] xPpp2r5e[tAb] is detectable
    *** cells: HEK293<xMyc> in BMLS
    *** source: 16537924-Fig-4c
  *** xPpp2ca[tAb] copptby[WB] xPpp2r2a[tAb] is detectable
    *** cells: HEK293T<xPpp2ca><xPpp2r2a> in BMS
    *** source: 19556239-Fig-3b
  *** xPpp2ca[tAb] snaggedby[WB] xMyc[His] is detectable
    *** cells: HEK293<xMyc> in BMLS
    *** inhibited by: xMyc(mnr)"delTAD" [substitution]
    *** source: 16537924-Fig-4b
*** Ppp2cb--
  *** Ppp2cb[Ab] copptby[WB] xKsr1[tAb] is detectable
    *** cells: NIH3T3 in BMLS
    *** unaffected by: Pdgf (5,10 min) [stim]
    *** source: 12932319-Fig-2b
  *** Ppp2cb[Ab] copptby[WB] xRaf1[tAb] is detectable
    *** cells: NIH3T3 in BMLS
    *** unaffected by: Pdgf (5,15 min) [stim]
    *** source: 12932319-Fig-2b
  *** Ppp2cb[MS] copptby[WB] xKsr1[tAb] is detectable
    *** cells: COS in BMS
    *** source: 12932319-Fig-1a
  *** Ppp2cb[MS] copptby[WB] xRaf1[tAb] is detectable
    *** cells: COS in BMS
    *** source: 12932319-Fig-4a
*** Ppp2cs--
  *** Ppp2cs[Ab] copptby[WB] Raf1[Ab] is detectable
    *** cells: BAC12F5 in BMLS
    *** unaffected by: Csf1 (0,5,15,30,60 min) [stim]
    *** source: 10801873-Fig-3a
  *** rPpp2r1?[Ab] boundby[WB] rRaf1[Ab] is detectable
    *** cells: none
    *** source: 10801873-Fig-4c
  *** xPpp2r1?[Ab] copptby[WB] xPpp2c?[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 10801873-Fig-4a
  *** Ppp2r1a[Ab] copptby[WB] xKsr1[tAb] is detectable
    *** cells: NIH3T3 in BMLS
    *** unaffected by: Pdgf (5,10 min) [stim]
    *** source: 12932319-Fig-2b
  *** Ppp2r1a[Ab] copptby[WB] xRaf1[tAb] is detectable
    *** cells: NIH3T3 in BMLS
    *** unaffected by: Pdgf (5,15 min) [stim]
    *** source: 12932319-Fig-2b
  *** Ppp2r1a[MS] copptby[WB] xKsr1[tAb] is detectable
    *** cells: COS in BMS
    *** source: 12932319-Fig-1a
  *** Ppp2r1a[MS] copptby[WB] xRaf1[tAb] is detectable
    *** cells: COS in BMS
    *** source: 12932319-Fig-4a
  *** Ppp2r1s[Ab] copptby[WB] Ppp2cs[Ab] is detectable
    *** cells: BAC12F5 in BMLS
    *** source: 10801873-Fig-3b
  *** Ppp2r1s[Ab] copptby[WB] Raf1[Ab] is detectable
    *** cells: BAC12F5 in BMLS
    *** unaffected by: Csf1 (0,5,15,30,60 min) [stim]
    *** source: 10801873-Fig-3a
  *** xPpp2r2a[Ab] copptby[WB] xAxin1[tAb] is detectable
    *** cells: HEK293T<xAxin1><xPpp2r2a> in BMS
    *** source: 19556239-Fig-5a
  *** xPpp2r2a[Ab] copptby[WB] xCtnnb1[tAb] is detectable
    *** cells: HEK293T<xCtnnb1><xPpp2r2a> in BMS
    *** source: 19556239-Fig-5a
  *** Ppp2r2a[Ab] copptby[WB] xKsr1[tAb] is undetectable
    *** cells: NIH3T3 in BMLS
    *** source: 12932319-Fig-2b
  *** Ppp2r2a[Ab] copptby[WB] xRaf1[tAb] is undetectable
    *** cells: NIH3T3 in BMLS
    *** source: 12932319-Fig-2b
  *** Ppp2r2a[MS] copptby[WB] xKsr1[tAb] is detectable
    *** cells: COS in BMS
    *** source: 12932319-Fig-1a
  *** Ppp2r2a[MS] copptby[WB] xRaf1[tAb] is detectable
    *** cells: COS in BMS
    *** source: 12932319-Fig-4a
  *** Ppp2r5a[Ab] copptby[WB] Myc[Ab] is detectable
    *** cells: HEK293 in BMLS
    *** source: 16537924-Fig-4d
  *** Ppp2r5a[Ab] copptby[WB] Myc[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 19131971-Fig-1b
  *** Ppp2r5a[Ab] copptby[WB] Sp1[Ab] is undetectable
    *** cells: HEK293 in BMS
    *** source: 19131971-Fig-1b
  *** Ppp2r5a[Ab] copptby[WB] xAxin1[tAb] is detectable
    *** cells: HEK293<xAxin1><xMyc> in BMS
    *** source: 19131971-Fig-1a
  *** xPpp2r5a[tAb] copptby[WB] xMyc[tAb] is detectable
    *** cells: HEK293<xPpp2r5a><xMyc> in BMLS
    *** inhibited by: xMyc(mnr)"delTAD" [substitution]
    *** source: 16537924-Fig-5a
  *** Ppp6c[Ab] copptby[WB] Tak1[Ab] is detectable
    *** cells: HEK293<xIL1R1> in BMS
    *** unaffected by: IL1b (1 min) [stim]
    *** source: 17079228(D)
  *** xPpp6c[tAb] copptby[WB] xTak1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 17079228(D)
*** Pras40--
  *** rPras40[32P] phos[32P-ATP] is unchanged by S6k1[Ab]IP
    *** cells: none
    *** IPfrom: 3T3L1 in BMLS "differentiated into adipocytes"
    *** unaffected by: rPras40(S183A) [substitution]
    *** unaffected by: rPras40(T246A) [substitution]
    *** source: 18372248-Fig-1a
  *** Pras40[Ab] copptby[WB] Mtor[Ab] is increased itpo (xPld1(K898R)"CIA" + xPld2(K758R)"CIA")
    *** cells: 786O in BMLS
    *** source: 19114562-Fig-7a
  *** Pras40[Ab] copptby[WB] Rictor[Ab] is undetectable
    *** cells: HEK293E in BMLS
    *** unaffected by: Ins (15 min) [stim]
    *** source: 17386266-Fig-3c
  *** Pras40[Ab] copptby[WB] Rictor[Ab] is undetectable
    *** cells: HEK293T in BMS
    *** source: 17277771-Fig-1b
  *** Pras40[Ab] copptby[WB] Tp53[Ab] is undetectable
    *** cells: HEK293E in BMLS
    *** unaffected by: Ins (15 min) [stim]
    *** source: 17386266-Fig-3b
  *** Pras40[Ab] copptby[WB] xRictor[tAb] is undetectable
    *** cells: HEK293T<xRictor> in BMS
    *** source: 17510057-Fig-1b
  *** Pras40[Ab] copptby[WB] xS6k1[tAb] is undetectable
    *** cells: HEK293T<xS6k1> in BMS
    *** source: 17277771-Fig-S3a
  *** Pras40[Ab]IP prot-exp[WB] is detectable
    *** cells: 3T3L1 in BMS "differentiated into adipocytes"
    *** source: 12524439-Fig-4
  *** Pras40[phosAb] phos(T246)[phosAb] is detectable 
    *** cells: 786O in BMS
    *** inhibited by: xPld1(K898R)"CIA" + xPld2(K758R)"CIA" [addition]
    *** source: 19114562-Fig-7a
  *** xPras40[tAb] copptby[WB] xRictor[tAb] is undetectable
    *** cells: HEK293T<xMtor><xRictor><xPras40> in BMS
    *** source: 17510057-Fig-1c
*** Prkd1--
  *** Prkd1[phosAb] phos(S916)[phosAb] is detectable
    *** cells: HELA in BMS
    *** does not req: Mtor [RNAi]
    *** source: 15268862-Fig-S2b
  *** Prkd1[phosAb] phos(S916)[phosAb] is detectable
    *** cells: HELA in BMS
    *** does not req: Raptor [RNAi]
    *** source: 15268862-Fig-S2b
  *** Prkd1[phosAb] phos(S916)[phosAb] is detectable
    *** cells: HELA in BMS
    *** does not req: Rictor [RNAi]
    *** source: 15268862-Fig-S2b
  *** Prkdc[Ab] copptby[WB] Atrip[Ab] is undetectable
    *** cells: HELA in BMS "nuclear-extract"
    *** comment: IP was performed in the presence of linear dsDNA
    *** source: 15758953-Fig-S4b
  *** Prkdc[Ab] copptby[WB] Ku80[Ab] is detectable
    *** cells: HELA in BMS "nuclear-extract"
    *** comment: IP was performed in the presence of linear dsDNA
    *** source: 15758953-Fig-S4b
  *** Prkdc[Ab] copptby[WB] Nbs1[Ab] is undetectable
    *** cells: HELA in BMS "nuclear-extract"
    *** comment: IP was performed in the presence of linear dsDNA
    *** source: 15758953-Fig-S4b
  *** Prkdc[Ab] copptby[WB] Nemo[Ab] is undetectable
    *** cells: HEK293 in BMS
    *** source: 16497931-Fig-2f
  *** Prkdc[Ab] copptby[WB] Tip60[Ab] is detectable
    *** cells: HELA in BMS
    *** source: 16603769-Fig-3a
  *** Prkdc[Ab] copptby[WB] xKu80[Ab] is detectable
    *** cells: XRS6Y<Ku80~null><xKu80> in BMS
    *** inhibited by: xKu80(1-718)"delC" [substitution]
    *** inhibited by: xKu80(E720A/E721A) [substitution]
    *** inhibited by: xKu80(D726A/D727A) [substitution]
    *** source: 15758953-Fig-4b
  *** Prkdc[Ab] copptby[WB] xTip60[tAb] is detectable
    *** cells: HELA<xTip60> in BMS
    *** comment: unaffected by addition of EtBr to lysates
    *** source: 16603769-Fig-S2b
  *** Prkdc[Ab] copptby[WB] xTip60[tAb] is detectable
    *** cells: HELA<xTip60> in BMS
    *** source: 16603769-Fig-S2a
  *** Prkdc[Ab] snaggedby[WB] dsDNA[biotin] is detectable
    *** cells: XRS6Y<Ku80~null><xKu80> in BMS
    *** reqs: xKu80 [omission]
    *** inhibited by: xKu80(1-718)"delC" [substitution]
    *** source: 15758953-Fig-4d
  *** Prkdc[Ab] snaggedby[WB] rAtrip(765-791)[biotin] is detectable
    *** cells: HELA in BMS "nuclear-extract"
    *** source: 15758953-Fig-S4a
  *** Prkdc[Ab] snaggedby[WB] rKu80(718-732)[biotin] is detectable
    *** cells: HELA in BMS "nuclear-extract"
    *** source: 15758953-Fig-S4a
  *** Prkdc[Ab] snaggedby[WB] rNbs1(734-754)[biotin] is detectable
    *** cells: HELA in BMS "nuclear-extract"
    *** inhibited by: rNbs1(675-697) [substitution]
    *** source: 15758953-Fig-S4a
  *** Prkdc[Ab] snaggedby[WB] sH2ax(123-143){phos(S140)}[GST] is undetectable
    *** cells: HELA in BMS "nuclear-extracts"
    *** unaffected by: sH2ax(123-143) [substitution]
    *** source: 16377563-Fig-1b
  *** ProAreg-gene mRNA[RTPCR] is increased itpo xMek1(S218D/S222D)
    *** cells: AKR2B in BMLS
    *** source: 23913859-Fig-3d
  *** ProEreg-gene mRNA[RTPCR] is increased itpo xMek1(S218D/S222D)
    *** cells: AKR2B in BMLS
    *** source: 23913859-Fig-3d
  *** ProHbegf-gene mRNA[RTPCR] is increased itpo xMek1(S218D/S222D)
    *** cells: AKR2B in BMLS
    *** source: 23913859-Fig-3d
  *** Proliferation[CellNumber] is decreased itao Gfi1 [RNAi]
    *** cells: HL60 in BMS
    *** source: 20190815-Fig-5a
  *** Proliferation[CellNumber] is decreased itao Gfi1 [RNAi]
    *** cells: TF1 in BMS
    *** source: 20190815-Fig-5b
  *** Proliferation[CellNumber] is decreased itao Tnik [RNAi]
    *** cells: DLD1 in BMS
    *** source: 20530691-Fig-4b
  *** Proliferation[CellNumber] is decreased itao Tnik [RNAi]
    *** cells: HCT116 in BMS
    *** source: 20530691-Fig-4b
  *** Proliferation[CellNumber] is decreased itpo xSocs2
    *** cells: BAF3 in BMS "containing IL3"
    *** source: 16199887-Fig-3a
  *** Proliferation[CellNumber] is increased itao Merlin [RNAi]
    *** cells: T29 in BMS
    *** reqs: Mlk3 [RNAi]
    *** source: 20890305-Fig-5a
  *** Proliferation[CellNumber] is unchanged itao Mlk3 [RNAi]
    *** cells: T29 in BMS
    *** source: 20890305-Fig-5a
  *** Proliferation[MethyleneBlue] is detectable
    *** cells: COS7<xErk2> in BMLS
    *** inhibited by: xErk2(S246A/P247A/S248A) [substitution]
    *** inhibited by: xErk2(del(246-278)) [substitution]
    *** inhibited by: xErk2(S246A/S248A) [substitution]
    *** unaffected by: xErk2(S246E/S248E) [substitution]
    *** source: 18760948-Fig-S7
  *** Proliferation[MTT] is decreased itpo xSocs2
    *** cells: BAF3 in BMS "containing IL3"
    *** source: 16199887-Fig-3b
  *** ProPdgfa-gene mRNA[RTPCR] is increased itpo xEgr1
    *** cells: C2C12 in BMS
    *** enhanced by: xEgr1(mnr)"Nab-insensitive" [substitution]
    *** source: 11111043-Fig-4
  *** ProPdgfa-gene mRNA[RTPCR] is increased itpo xEgr2
    *** cells: C2C12 in BMS
    *** source: 11111043-Fig-4
  *** ProPdgfa-gene mRNA[RTPCR] is unchanged itpo xEgr1
    *** cells: NEURO2A in BMS
    *** unaffected by: xEgr1(mnr)"Nab-insensitive" [substitution]
    *** source: 11111043-Fig-4
  *** ProPdgfa-gene mRNA[RTPCR] is unchanged itpo xEgr2
    *** cells: NEURO2A in BMS
    *** source: 11111043-Fig-4
  *** ProTnf-gene mRNA[MicroArray] is detectable
    *** cells: THP1 in BMS
    *** reqs: Ampka1 [RNAi]
    *** source: 22833096-Table-S1a
  *** ProTnf-gene mRNA[Northern] is increased itpo xHif1a
    *** cells: CHANG in BMS
    *** enhanced by: xJun [addition]
    *** source: 17451682-Fig-5c
  *** ProTnf-gene mRNA[Northern] is increased itpo xJun
    *** cells: CHANG in BMS
    *** enhanced by: xHif1a [addition]
    *** source: 17451682-Fig-5c
  *** ProTnf-gene mRNA[RTPCR] is detectable
    *** cells: HACAT in BMS
    *** reqs: Egr1 [RNAi]
    *** source: 18675783-Fig-3b
  *** ProTnf-gene mRNA[RTPCR] is detectable
    *** cells: THP1 in BMS
    *** reqs: Ampka1 [RNAi]
    *** source: 22833096-Fig-4c
  *** ProTnf-gene promo-reporter[Luc] is detectable
    *** cells: HACAT in BMS
    *** reqs: Egr1 [RNAi]
    *** source: 18675783-Fig-3c
  *** ProTnf-gene promo-reporter[Luc] is increased itpo xEgr1
    *** cells: HACAT in BMS
    *** comment: inhibited by mutation of Egr1 binding site (-169)
    *** source: 18675783-Fig-2d
  *** ProTnf-gene promo-reporter[Luc] is increased itpo xEgr1
    *** cells: HACAT in BMS
    *** source: 18675783-Fig-2c
  *** ProTnf-gene promo-reporter[Luc] is increased itpo xHif1a
    *** cells: CHANG in BMS
    *** source: 17451682-Fig-5a
  *** ProTnf-gene promo-reporter[Luc] is increased itpo xHif1a
    *** cells: HEPG2 in BMS
    *** source: 17451682-Fig-5a
  *** Protor1[Ab] copptby[WB] Mtor[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 17461779-Fig-3a
  *** Protor1[Ab] copptby[WB] Mtor[Ab] is undetectable
    *** cells: mEFs<Rictor~null> in BMS
    *** source: 18925875-Fig-4a
  *** Protor1[Ab] copptby[WB] Rictor[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 17461779-Fig-3a
  *** Protor1[Ab] copptby[WB] Rictor[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 18925875-Fig-3a
  *** Protor1[Ab] copptby[WB] Rictor[Ab] is detectable
    *** cells: mEFs in BMS
    *** does not req: Mlst8 [KO]
    *** source: 18925875-Fig-3d
  *** Protor1[Ab] copptby[WB] Sin1[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 17461779-Fig-3a
  *** xProtor1[Ab] copptby[WB] xSin1[Ab] is detectable
    *** cells: HEK293<xMtor><xRictor><xSin1><xProtor1><xMlst8> in BMS
    *** does not req: xMtor [omission]
    *** reqs: xRictor [omission]
    *** source: 17461779-Fig-4a
  *** Protor1[Ab] prot-exp[WB] is detectable
    *** cells: mEFs in BMS
    *** partially reqs: Rictor [KO]
    *** source: 17461779-Fig-4b
  *** Protor1[Ab]IP prot-exp[WB] is detectable
    *** cells: mEFs in BMS
    *** partially reqs: Rictor [KO]
    *** source: 17461779-Fig-4b
  *** xPrph[tAb]IP Yphos[pYAb] is detectable
    *** cells: COS7<xTrka><xPrph> in BMS
    *** partially inhibited by: xTrka(K547A) [substitution]
    *** source: 10691301-Fig-7
  *** xPsmb6[tAb]IP Yphos[pYAb] is detectable
    *** cells: COS7<xTrka><xPsmb6> in BMS
    *** partially inhibited by: xTrka(K547A) [substitution]
    *** source: 10691301-Fig-7
*** Psmd4--
  *** rPsmd4[Ab] boundby[WB] rUbiq{K48poly}[Sepharose] is detectable
    *** cells: none
    *** source: 16603398-Fig-6a
  *** rPsmd4[Ab] boundby[WB] rUbiq{K63poly}[Sepharose] is detectable
    *** cells: none
    *** source: 16603398-Fig-6a
  *** rPsmd4[Ab] boundby[WB] rUbiq{mono}[Sepharose] is undetectable
    *** cells: none
    *** source: 16603398-Fig-6a
*** Pten-- Pten-gene--
  *** Pten-gene mRNA[RTPCR] is decreased itpo xHras(G12V)
    *** cells: NIH3T3 in BMS
    *** source: 17974977-Fig-1b
  *** Pten-gene mRNA[RTPCR] is decreased itpo xRbpj
    *** cells: HEK293 in BMS
    *** reversed by: xRbpj(R218H) [substitution]
    *** source: 17245125-Fig-2
  *** Pten-gene mRNA[RTPCR] is increased itao Ampka1 [RNAi]
    *** cells: THP1 in BMS
    *** reqs: Ampka1 [RNAi]
    *** source: 22833096-Fig-7b
  *** Pten-gene mRNA[RTPCR] is increased itao Jun [KO]
    *** cells: mEFs in BMS
    *** source: 17974977-Fig-3a
  *** Pten-gene mRNA[RTPCR] is increased itpo xNotch1(1754-2555)
    *** cells: HEK293 in BMS
    *** source: 17245125-Fig-2
  *** Pten-gene promo-reporter[Luc] is decreased itpo xHras(G12V)
    *** cells: NIH3T3 in BMS
    *** source: 17974977-Fig-1c
  *** Pten-gene promo-reporter[Luc] is decreased itpo xHras(G12V)
    *** cells: NIH3T3<Rela~null> in BMS
    *** source: 17974977-Fig-2d
  *** Pten-gene promo-reporter[Luc] is decreased itpo xHras(G12V)
    *** cells: NIH3T3<Tp53~null> in BMS
    *** source: 17974977-Fig-2d
  *** Pten-gene promo-reporter[Luc] is decreased itpo xJun
    *** cells: mEFs<Jun~null> in BMS
    *** source: 17974977-Fig-3b
  *** Pten-gene promo-reporter[Luc] is decreased itpo xRbpj
    *** cells: HEK293 in BMS
    *** reversed by: xRbpj(R218H) [substitution]
    *** source: 17245125-Fig-4
  *** Pten-gene promo-reporter[Luc] is increased itao Jun [KO]
    *** cells: mEFs in BMS
    *** source: 17974977-Fig-3b
  *** Pten-gene promo-reporter[Luc] is increased itpo xAkt1(myr)
    *** cells: NIH3T3 in BMS
    *** source: 17974977-Fig-2c
  *** Pten-gene promo-reporter[Luc] is increased itpo xApex1
    *** cells: HCT116 in BMS
    *** does not req: Tp53 [HRKnockdown]
    *** source: 18324520-Fig-5b
  *** Pten-gene promo-reporter[Luc] is increased itpo xApex1
    *** cells: HELA in BMS
    *** inhibited by: xApex1(mnr)"R6/R7-non-acetable" [substitution]
    *** source: 18324520-Fig-1b
  *** Pten-gene promo-reporter[Luc] is increased itpo xEgr1
    *** cells: FRTL in BMS
    *** source: 15231710-Fig-1
  *** Pten-gene promo-reporter[Luc] is increased itpo xEgr1
    *** cells: HCT116 in BMS
    *** partially reqs: Tp53 [HRKnockdown]
    *** source: 18324520-Fig-5b
  *** Pten-gene promo-reporter[Luc] is increased itpo xJun(del(3-122))"DN"
    *** cells: NIH3T3 in BMS
    *** source: 17974977-Fig-3c
  *** Pten-gene promo-reporter[Luc] is increased itpo xNotch1(1754-2555)
    *** cells: HEK293 in BMS
    *** source: 17245125-Fig-4
  *** Pten-gene promo-reporter[Luc] is unchanged itpo xAkt1(K179A/T308A/S473A)"DN"
    *** cells: NIH3T3 in BMS
    *** source: 17974977-Fig-2c
  *** Pten-gene promo-reporter[Luc] is unchanged itpo xJun(mnr)"Leucine-zipper-deleted"
    *** cells: NIH3T3 in BMS
    *** source: 17974977-Fig-3c
  *** Pten[Ab] prot-exp[WB] is decreased itpo xHras(G12V)
    *** cells: MCF7 in BMS
    *** source: 17974977-Fig-1a
  *** Pten[Ab] prot-exp[WB] is decreased itpo xHras(G12V)
    *** cells: NIH3T3 in BMS
    *** source: 17974977-Fig-1a
  *** Pten[Ab] prot-exp[WB] is decreased itpo xHras(G12V)
    *** cells: NIH3T3 in BMS
    *** source: 17974977-Fig-2b
  *** Pten[Ab] prot-exp[WB] is decreased itpo xHras(Q61L)
    *** cells: mEFs in BMS
    *** reqs: Jun [KO]
    *** source: 17974977-Fig-3d
  *** Pten[Ab] prot-exp[WB] is decreased itpo xJun
    *** cells: NIH3T3 in BMS
    *** source: 17974977-Fig-3a
  *** Pten[Ab] prot-exp[WB] is decreased itpo xRaf1(mnr)"CA"
    *** cells: NIH3T3 in BMS
    *** source: 17974977-Fig-2b
  *** Pten[Ab] prot-exp[WB] is detectable
    *** cells: H838 in BMS
    *** source: 17974977-Fig-1a
  *** Pten[Ab] prot-exp[WB] is detectable
    *** cells: HELA in BMS
    *** partially reqs: Apex1 [RNAi]
    *** source: 18324520-Fig-1a
  *** Pten[Ab] prot-exp[WB] is increased itao Jun [KO]
    *** cells: mEFs in BMS
    *** source: 17974977-Fig-3a
  *** Pten[Ab] prot-exp[WB] is increased itpo xApex1
    *** cells: HELA in BMS
    *** inhibited by: xApex1(K6R/K7R)"non-acetable" [substitution]
    *** source: 18324520-Fig-1a
  *** Pten[Ab] prot-exp[WB] is unchanged itpo xFos
    *** cells: NIH3T3 in BMS
    *** source: 17974977-Fig-3a
  *** Pten[Ab] prot-exp[WB] is undetectable
    *** cells: H157 in BMS
    *** comment: H157 have mutant Kras status (no evidence provided)
    *** source: 17974977-Fig-1a
  *** Ptgs2-gene mRNA[RTPCR] is decreased itao Tpl2 [KO]
    *** cells: mBMMs in BMS
    *** source: 12234923-Fig-3a
  *** Ptgs2-gene promo-reporter[Luc] is increased itpo xTpl2
    *** cells: RAW2647 in BMS
    *** source: 12234923-Fig-3c
  *** Ptgs2[Ab] prot-exp[WB] is increased itpo xTpl2
    *** cells: RAW2647 in BMS
    *** source: 12234923-Fig-2b
  *** Pthlh-gene mRNA[RTPCR] is detectable
    *** cells: HACAT in BMS
    *** reqs: Ets1 [RNAi]
    *** source: 18955504-Fig-S4c
  *** Ptip[Ab] snaggedby[WB] sH2ax(123-143){phos(S140)}[GST] is undetectable
    *** cells: HELA in BMS "nuclear-extracts"
    *** unaffected by: sH2ax(123-143) [substitution]
    *** source: 16377563-Fig-1b
  *** rPtk6 IVKA(peptide)[32P-ATP] is detectable
    *** cells: none
    *** comment: enhanced by addition of a poly-proline peptide
    *** source: 12121988-Fig-6
  *** rPtk6 IVKA(peptide)[32P-ATP] is detectable
    *** cells: none
    *** comment: enhanced by addition of SH2 binding peptide Glu-Pro-Gln-Tyr(P)-Glu-Glu-Ile-Pro-Ile-Lys-Gln
    *** comment: enhanced by addition of phosphorylated Ptk6 C-terminal peptide Phe-Thr-Ser-Tyr(P)-Glu-Gln-Pro-Thr
    *** source: 12121988-Fig-5
  *** rPtk6 IVKA(peptide)[32P-ATP] is detectable
    *** cells: none
    *** comment: enhanced by preincubation of rPtk6 with unlabeled ATP
    *** source: 12121988-Fig-4
  *** rPtk6 IVKA(peptide)[32P-ATP] is detectable
    *** cells: none
    *** inhibited by: rPtk6(Y342A) [substitution]
    *** enhanced by: rPtk6(Y447F) [substitution]
    *** partially inhibited by: rPtk6(Y342A/Y447F) [substitution]
    *** source: 12121988-Fig-4
  *** xPtk6(myr)[Ab] infraction(membrane)[WB] is detectable
    *** cells: SW620<xPtk6> in BMS
    *** unaffected by: xPtk6(myr/Y447F)"CA" [substitution]
    *** unaffected by: xPtk6(myr/K219M)"KD" [substitution]
    *** source: 20016641-Fig-5b
  *** xPtk6(NLS)[Ab] infraction(nuclear)[WB] is detectable
    *** cells: HEK293<xPtk6> in BMS
    *** unaffected by: xPtk6(NLS/Y447F)"CA" [substitution]
    *** unaffected by: xPtk6(NLS/K219M)"KD" [substitution]
    *** source: 20016641-Fig-5b
  *** rPtk6[32P] IVKA(auto)[32P-ATP] is detectable
    *** cells: none
    *** comment: phos sites were shown to be Y342,Y351 Y61,Y66,Y13 by MS
    *** source: 12121988-Fig-3
  *** rPtk6[32P] IVKA(auto)[32P-ATP] is detectable
    *** cells: none
    *** partially inhibited by: rPtk6(Y342A) [substitution]
    *** partially inhibited by: rPtk6(Y447F) [substitution]
    *** partially inhibited by: rPtk6(Y342A/Y447F) [substitution]
    *** source: 12121988-Fig-2
  *** Ptk6[Ab] copptby[WB] Pxn[Ab] is detectable
    *** cells: A431 in BMS
    *** source: 15572663-Fig-2a
  *** xPtk6[Ab] copptby[WB] Pxn[Ab] is detectable
    *** cells: COS1 in BMS
    *** source: 15572663-Fig-2a
  *** xPtk6[Ab] copptby[WB] xCtnnb1[Ab] is detectable
    *** cells: HEK293<xCtnnb1><xPtk6> in BMS
    *** unaffected by: xPtk6(Y447F)"CA" [substitution]
    *** unaffected by: xPtk6(K219M)"KD" [substitution]
    *** source: 20016641-Fig-1c
  *** xPtk6[Ab] infraction(cyto-nuc)[WB] is detectable
    *** cells: HEK293<xPtk6> in BMS
    *** unaffected by: xPtk6(Y447F)"CA" [addition]
    *** unaffected by: xPtk6(K219M)"KD" [addition]
    *** source: 20016641-Fig-2a
  *** xPtk6[Ab] Yphos[pYAb-ppt] is detectable
    *** cells: HEK293<xCtnnb1><xPtk6> in BMS
    *** partially inhibited by: xPtk6(Y447F)"CA" [substitution]
    *** inhibited by: xPtk6(K219M)"KD" [substitution]
    *** source: 20016641-Fig-1b
  *** xPtk6[Ab]IP Yphos[pYAb-ppt] is detectable
    *** cells: COS1<xPtk6> in BMLS
    *** enhanced by: xPtk6(Y447F) [substitution]
    *** inhibited by: xPtk6(K219M)"KD" [substitution]
    *** source: 15539407-Fig-3a
  *** xPtk6[Ab]IP Yphos[pYAb] is detectable
    *** cells: HEK293<xPtk6> in BMS
    *** inhibited by: xPtk6(K219M)"KD" [substitution]   
    *** inhibited by: xPtk6(Y342A) [substitution]   
    *** enhanced by: xPtk6(Y447F) [substitution]
    *** unaffected by: xPtk6(W44A) [substitution]
    *** source: 12121988-Fig-8
  *** Ptpn2[Ab] colocwith[IHC] Itga1[Ab] is detectable
    *** cells: HELA in BMLS "on Fibronectin"
    *** source: 15592458(D)
  *** Ptpn6[Ab] copptby[WB] Pik3rs[Ab] is detectable
    *** cells: RAMOS in BMLS "treated with IL4 for 1 min"
    *** source: 9065461-Fig-4b
*** Ptprf--
  *** Ptprf[Ab] copptby[WB] Cdh1[Ab] is detectable
    *** cells: MCF7 in BMS
    *** unaffected by: Egf (30 min) [stim]
    *** source: 10187801-Fig-5a,5b
*** Pxn--
  *** rPxn((1-238)/Y31F)[32P] phos[32P-ATP] is increased by xSrc[Ab]IP
    *** cells: none
    *** IPfrom: cECs<xSrc> in BMS
    *** unaffected by: rPxn((1-238)/Y40F) [substitution]
    *** unaffected by: rPxn((1-238)/Y88F) [substitution]
    *** unaffected by: rPxn((1-238)/Y118F) [substitution]
    *** unaffected by: rPxn((1-238)/Y31F/Y40F) [substitution]
    *** unaffected by: rPxn((1-238)/Y31F/Y118F) [substitution]
    *** inhibited by: rPxn((1-238)/Y31F/Y40F/Y88F/Y118F) [substitution]
    *** source: 11695992-Fig-1
  *** rPxn(1-323)[32P] phos[32P-ATP] is increased by pSrc{act}
    *** cells: none
    *** source: 14636584-Fig-3c
  *** rPxn(155-391) phos[32P-ATP] is increased by (pMkk7{act} + rJnk1)
    *** cells: none
    *** reqs: both [omission]
    *** source: 12858963-Fig-2a
  *** rPxn(155-391) phos[32P-ATP] is increased by rJnk1{act}
    *** cells: none
    *** inhibited by: rPxn((155-391)/S178A) [substitution]
    *** source: 12858963-Fig-2a
  *** xPxn(Y31F/Y118F)[phosAb] phos(S126)[phosAb] is detectable
    *** cells: RAW2647<xPxn> in BMLS
    *** inhibited by: xPxn [substitution]
    *** source: 16537926-Fig-3a
  *** rPxn[32P] phos[32P-ATP] is increased by xAbl1[tAb]IP
    *** cells: none
    *** IPfrom: mEFs<Abl1~null><xAbl1> in BMS "treated with Fn1-adherence for 25 min"
    *** source: 9603926-Fig-5c
  *** Pxn[Ab] copptby[WB] Apc[Ab] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xDvl1(337-670) [addition]
    *** source: 20224554-Fig-S16d
  *** Pxn[Ab] copptby[WB] Apc[Ab] is detectable
    *** cells: HELAS3 in BMS
    *** source: 20224554-Fig-5f
  *** Pxn[Ab] copptby[WB] Dvls[Ab] is undetectable
    *** cells: HELAS3 in BMS
    *** source: 20224554-Fig-5e
  *** Pxn[Ab] copptby[WB] Itgavb3[Ab] is detectable-but unchanged itpo xF2R
    *** cells: SB2 in BMS
    *** source: 11278329-Fig-5b
  *** Pxn[Ab] copptby[WB] Itgavb5[Ab] is increased itpo xF2R
    *** cells: SB2 in BMS
    *** source: 11278329-Fig-5a
  *** Pxn[Ab] copptby[WB] xApc(221-958)[tAb] is detectable
    *** cells: COS7<xApc(221-958)> in BMS
    *** inhibited by: xApc(1-220)"NT" [substitution]
    *** inhibited by: xApc(959-1338)"M2" [substitution]
    *** inhibited by: xApc(1211-2075)"M3" [substitution]
    *** inhibited by: xApc(2079-2843)"CT" [substitution]
    *** source: 20224554-Fig-5h
  *** Pxn[Ab] copptby[WB] xApc(221-958)[tAb] is detectable
    *** cells: COS7<xApc(221-958)> in BMS
    *** unaffected by: xApc(221-731) [substitution]
    *** unaffected by: xApc(221-597) [substitution]
    *** unaffected by: xApc(221-458) [substitution]
    *** source: 20224554-Fig-S15b
  *** Pxn[Ab] infraction(membrane)[WB] is decreased itpo xArhGef7
    *** cells: NIH3T3 in BMS
    *** source: 20375009-Fig-8b
  *** Pxn[Ab] infraction(membrane)[WB] is increased itpo xArhGef7(Y442F)
    *** cells: NIH3T3 in BMS
    *** inhibited by: xGit1(L294A/C295A) [addition]
    *** source: 20375009-Fig-8b
  *** xPxn[Ab]IP phos[32P-ATP] is increased by xSrc[Ab]IP
    *** cells: none
    *** IP1from: cECs<xPxn> in BMS
    *** IP2from: cECs<xSrc> in BMS
    *** source: 11695992-Fig-1
  *** xPxn[Ab]IP phos[32Pi] is increased itpo xJnk1
    *** cells: HEK293 in BMS
    *** inhibited by: xPxn(S178A) [substitution]
    *** source: 12858963-Fig-3c
  *** Pxn[Ab]IP Yphos[pYAb] is decreased by rShp2(mnr)"PTPaseDomain"
    *** cells: none
    *** comment: IP is from MDAMB468 in BMLS
    *** source: 14665621-Fig-3a
  *** Pxn[Ab]IP Yphos[pYAb] is decreased itpo xPtpn12
    *** cells: HEK293 in BMS
    *** source: 11337490-Fig-8b
  *** Pxn[Ab]IP Yphos[pYAb] is increased itpo xAbl1
    *** cells: HEK293T in BMS
    *** inhibited by: xAbl1(mnr)"KD" [substitution]
    *** source: 12777393-Fig-4b
  *** Pxn[Ab]IP Yphos[pYAb] is increased itpo xAbl1
    *** cells: HEK293T in BMS
    *** source: 12777393-Fig-4c
  *** Pxn[Ab]IP Yphos[pYAb] is increased itpo xDok2
    *** cells: HEK293 in BMS
    *** source: 12777393-Fig-4b
  *** Pxn[Ab]IP Yphos[pYAb] is increased itpo xDok2
    *** cells: HEK293T<xAbl1> in BMS
    *** unaffected by: xDok2(1-257) [substitution]
    *** inhibited by: xDok2(1-321) [substitution]
    *** source: 12777393-Fig-4c
  *** Pxn[Ab]IP Yphos[pYAb] is increased itpo xFak2
    *** cells: HEK293 in BMS
    *** inhibited by: xPtpn12 [addition]
    *** partially inhibited by: xPtpn12(del(367-400)) [addition]
    *** partially inhibited by: xPtpn12(del(297-493)) [addition]
    *** inhibited by: xPtpn12(P337A) [addition]
    *** source: 11337490-Fig-8b
  *** xPxn[Ab]IP Yphos[pYAb] is increased itpo xHck(Y522F)"CA"
    *** cells: HEK293T in BMS
    *** unaffected by: xHck(Y522F/W114A) [substitution]
    *** source: 10799548-Fig-2d
  *** Pxn[Ab]IP Yphos[pYAb] is unchanged itpo xGab1(Y627F/Y659F)
    *** cells: MDAMB468 in BMLS
    *** source: 14665621-Fig-4b
  *** rPxn[GST] Yphos[pYAb] is increased by xAbl1[tAb]IP
    *** cells: none
    *** IPfrom: mEFs<Abl1~null><xAbl1> in BMS "treated with Fn1-adherence for 25 min"
    *** inhibited by: xAbl1(mnr)"KD" [substitution]
    *** source: 9603926-Fig-5c
  *** xPxn[GST]IP IVKA(MBP)[32P-ATP] is increased itpo xCdc42(G12V)"CA"
    *** cells: COS7<xPak3> in BMS
    *** inhibited by: xPak3(78-146)"auto-inhibitory-domain" [addition]
    *** source: 11096073-Fig-5a
  *** xPxn[phosAb] phos(S83)[phosAb] is detectable
    *** cells: MIMCD3<xPxn> in BMLS "treated with Hgf fof 10 min"
    *** inhibited by: xPxn(S83A) [substitution]
    *** source: 15494312-Fig-1d
  *** Pxn[phosAb] phos(S126)[phosAb] is increased itpo xMek1(mnr)"CA"
    *** cells: HEK293 in BMS
    *** inhibited by: xMek1 [substitution]
    *** source: 16537926-Fig-2d
  *** Pxn[phosAb] phos(Y31)[phosAb] is decreased itpo xShp2
    *** cells: mEFs<Shp2~null> in BMLS
    *** source: 14967142-Fig-5d
  *** Pxn[phosAb] phos(Y118)[phosAb] is decreased itpo xShp2
    *** cells: mEFs<Shp2~null> in BMLS
    *** source: 14967142-Fig-5d
  *** Pxn[phosAb] phos(Y118)[phosAb] is detectable
    *** cells: NIH3T3 in BMS
    *** does not req: Raptor [RNAi]
    *** source: 15467718-Fig-4a
  *** Pxn[phosAb] phos(Y118)[phosAb] is detectable
    *** cells: NIH3T3 in BMS
    *** partially reqs: Mtor [RNAi]
    *** source: 15467718-Fig-4a
  *** Pxn[phosAb] phos(Y118)[phosAb] is detectable
    *** cells: NIH3T3 in BMS
    *** reqs: Mlst8 [RNAi]
    *** source: 15467718-Fig-4a
  *** Pxn[phosAb] phos(Y118)[phosAb] is detectable
    *** cells: NIH3T3 in BMS
    *** reqs: Rictor [RNAi]
    *** source: 15467718-Fig-4a
  *** xPxn[tAb]IP Yphos[pYAb] is increased itpo xFak2
    *** cells: HEK293<xPxn> in BMS
    *** inhibited by: xFak2(mnr)"KD" [substitution]  
    *** source: 16199135-Fig-2d
*** Pycard--
*** Pyrin--
  *** Pyrin[Ab] copptby[WB] Casp1[Ab] is detectable
    *** cells: THP1 in BMS
    *** source: 16785446(D)
  *** rRab3a GDP-dissociation[3H-GDP] is unchanged by rRalGds
    *** cells: none
    *** source: 8094051-Fig-5
  *** rRab3a GTP-association[35S-GTPgS] is unchanged by rAbr(104-383)
    *** cells: none
    *** source: 9659915-Fig-6a
  *** rRab3a GTP-association[35S-GTPgS] is unchanged by rArhGef6(155-545)
    *** cells: none
    *** source: 9659915-Fig-6a
*** Rab3a--
  *** rRab4a GDP-dissociation[3H-GDP] is unchanged by rRin1
    *** cells: none
    *** source: 11703925-Fig-2c
*** Rab4a--
  *** xRab4a[tAb] copptby[WB] xZnf364[tAb] is undetectable
    *** cells: COS1 in BMS
    *** source: 12972561(D)
  *** xRab4a[tAb] snaggedby[WB] rZnf364[GST] is undetectable
    *** cells: COS1 in BMS
    *** source: 12972561(D)
*** Rab5b--
*** Rab5c--
*** Rab7a--
  *** xRab7a[tAb] snaggedby[WB] rZnf364[GST] is detectable
    *** cells: COS1 in BMS
    *** inhibited by: xRab7a(T22N)"DN" [addition]
    *** inhibited by: xRab7a(N125I)"DN" [addition]
    *** source: 12972561(D)
*** Rab8--
  *** xRab8?[tAb] copptby[WB] xZnf364[tAb] is undetectable
    *** cells: COS1 in BMS
    *** source: 12972561(D)
  *** xRab8?[tAb] snaggedby[WB] rZnf364[GST] is undetectable
    *** cells: COS1 in BMS
    *** source: 12972561(D)
  *** rRab11a GDP-dissociation[3H-GDP] is unchanged by rRin1
    *** cells: none
    *** source: 11703925-Fig-2c
*** Rab11a--
  *** rRac1 GDP-dissociation[3H-GDP] is unchanged by rLck
    *** cells: none
    *** source: 8990121-Fig-1a
  *** rRac1 GTP-association[35S-GTPgS] is increased by rAbr(104-383)
    *** cells: none
    *** source: 9659915-Fig-6a
  *** rRac1 GTP-association[35S-GTPgS] is increased by rArhGef6(155-545)
    *** cells: none
    *** source: 9659915-Fig-6a
  *** rRac1 GTP-hydrolysis[32P-GTP] is unchanged by rSipa1
    *** cells: none
    *** source: 9346962-Fig-3a
*** Rac1--
  *** xRac1(G12V)[tAb] snaggedby[WB] rElmo2(1-362)[GST] is undetectable
    *** cells: HEK293T<xRac1(G12V)> in BMS
    *** source: 12879077-Fig-1b
  *** xRac1(G12V)[tAb] snaggedby[WB] rPak1(mnr)"CRIB"[GST] is detectable
    *** cells: HEK293T<xRac1(G12V)> in BMS
    *** source: 12879077-Fig-1b
  *** xRac1(G12V)[tAb] snaggedby[WB] rRtkn(mnr)"RBD"[GST] is undetectable
    *** cells: HEK293T<xRac1(G12V)> in BMS
    *** source: 12879077-Fig-1b
  *** Rac1[Ab] copptby[WB] Pak2[Ab] is decreased itpo xErbin
    *** cells: AKR2B in BMLS "treated with Tgfb1 for 45 min"
    *** reqs: Merlin [RNAi]
    *** source: 19289088-Fig-5d
  *** Rac1[Ab] GTP-association[BDPD] is decreased itpo xAdrbk1(Cterm)"CA"
    *** cells: bAECs in BMLS
    *** source: 16339142(D)
  *** Rac1[Ab] GTP-association[BDPD] is decreased itpo xCdGap
    *** cells: COS1 in BMLS
    *** source: 14699061-Fig-7d
  *** Rac1[Ab] GTP-association[BDPD] is detectable
    *** cells: bAECs in BMLS
    *** does not req: Ampka1 [RNAi]
    *** source: 17519230(D)
  *** Rac1[Ab] GTP-association[BDPD] is detectable
    *** cells: COS7 in BMS
    *** comment: inhibited by cell suspension
    *** source: 16492808-Fig-1d
  *** Rac1[Ab] GTP-association[BDPD] is detectable
    *** cells: mEFs in BMS
    *** reqs: Shc1p66 [KO]
    *** source: 16520382-Fig-1a
  *** Rac1[Ab] GTP-association[BDPD] is detectable
    *** cells: mEFs<Shc1p66~null><xShc1p66> in BMS
    *** inhibited by: xShc1p66(P47A/P50A) [substitution]
    *** inhibited by: xShc1p66(CH2) [substitution]
    *** source: 16520382-Fig-1a
  *** Rac1[Ab] GTP-association[BDPD] is detectable
    *** cells: NIH3T3 in BMS
    *** does not req: Raptor [RNAi]
    *** source: 15467718-Fig-5b
  *** Rac1[Ab] GTP-association[BDPD] is detectable
    *** cells: NIH3T3 in BMS
    *** partially reqs: Mlst8 [RNAi]
    *** source: 15467718-Fig-5b
  *** Rac1[Ab] GTP-association[BDPD] is detectable
    *** cells: NIH3T3 in BMS
    *** partially reqs: Mtor [RNAi]
    *** source: 15467718-Fig-5b
  *** Rac1[Ab] GTP-association[BDPD] is detectable
    *** cells: NIH3T3 in BMS
    *** partially reqs: Rictor [RNAi]
    *** source: 15467718-Fig-5b
  *** Rac1[Ab] GTP-association[BDPD] is detectable
    *** cells: NIH3T3<xNckipsd> in BMS "membrane-fractions"
    *** enhanced by: xDiaph1(mnr)"CA" [addition]
    *** partially inhibited by: xDiaph1(mnr)"CA/dFH1" [addition]
    *** source: 14765113-Fig-4c
  *** Rac1[Ab] GTP-association[BDPD] is detectable
    *** cells: NIH3T3<xNckipsd> in BMS "membrane-fractions"
    *** partially inhibited by: xNckipsd(del(170-249))"dPro" [substitution]
    *** source: 14765113-Fig-4c
  *** Rac1[Ab] GTP-association[BDPD] is increased itao Cav1 [RNAi]
    *** cells: bAECs in BMLS
    *** source: 15292187(D)
  *** Rac1[Ab] GTP-association[BDPD] is increased itpo xCdc42(Q61L)"CA"
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-4
  *** Rac1[Ab] GTP-association[BDPD] is increased itpo xDock1
    *** cells: HEK293T in BMS
    *** enhanced by: xElmo2 [addition]
    *** unaffected by: xElmo2(1-618) [addition]
    *** source: 12879077-Fig-2b
  *** Rac1[Ab] GTP-association[BDPD] is increased itpo xElmo2
    *** cells: HEK293T<xDock1> in BMS
    *** enhanced by: xRhog(G12V) [addition]
    *** inhibited by: xRhog(G12V/F37A) [addition]
    *** source: 12879077-Fig-2b
  *** Rac1[Ab] GTP-association[BDPD] is increased itpo xHras(Q61L)"CA"
    *** cells: NIH3T3 in BMS
    *** source: 11788587-Fig-8a
  *** Rac1[Ab] GTP-association[BDPD] is increased itpo xPtk6
    *** cells: COS1 in BMLS
    *** inhibited by: xCrk(R38K)"DN" [addition]
    *** inhibited by: xCrk(W170K)"DN" [addition]
    *** source: 15572663-Fig-4a,4b
  *** Rac1[Ab] GTP-association[BDPD] is increased itpo xPtk6
    *** cells: COS1 in BMLS
    *** inhibited by: xPxn(Y31F/Y118F)"DN" [addition]
    *** source: 15572663-Fig-4a,4b
  *** Rac1[Ab] GTP-association[BDPD] is increased itpo xRhog(G12V)
    *** cells: HEK293T in BMS
    *** enhanced by: xDock1 [addition]
    *** source: 12879077-Fig-2b
  *** Rac1[Ab] GTP-association[BDPD] is increased itpo xRhog(G12V)
    *** cells: HEK293T<xDock1><xElmo2> in BMS
    *** inhibited by: xElmo2(1-618) [substitution]
    *** source: 12879077-Fig-2b
  *** Rac1[Ab] GTP-association[BDPD] is increased itpo xRhog(G12V)
    *** cells: HEK293T<xDock1><xElmo2> in BMS
    *** inhibited by: xRhog(G12V/F37A) [substitution]
    *** source: 12879077-Fig-2b
  *** Rac1[Ab] GTP-association[BDPD] is increased itpo xRhog(Q61L)"CA"
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-4
  *** Rac1[Ab] GTP-association[BDPD] is increased itpo xSrc(mnr)"vSrc"
    *** cells: HEK293 in BMS
    *** enhanced by: xRasGrf1 [addition]
    *** source: 10681520-Fig-2c
  *** Rac1[Ab] GTP-association[BDPD] is increased itpo xSrc(mnr)"vSrc"
    *** cells: NIH3T3 in BMLS
    *** source: 12810717(D)
  *** Rac1[Ab] GTP-association[BDPD] is increased itpo xSrc(Y530F)"CA"
    *** cells: HEK293 in BMS
    *** enhanced by: xTiam1 [addition]
    *** source: 12810717(D)
  *** Rac1[Ab] GTP-association[BDPD] is unchanged itpo xRras2(Q72L)"CA"
    *** cells: NIH3T3 in BMS
    *** source: 11788587-Fig-8a
  *** xRac1[tAb] copptby[WB] xIL18Rap[GST] is detectable
    *** cells: HEK293<xRac1><xIL18Rap> in BMS
    *** source: 18003981-Fig-4b
  *** xRac1[tAb] GTP-association[BDPD] is increased itpo xDock4(P1718L)
    *** cells: HEK293T in BMS
    *** inhibited by: xDock4(WT) [substitution]
    *** source: 12628187-Fig-4c
  *** xRac1[tAb] GTP-association[BDPD] is increased itpo xNckipsd
    *** cells: HEK293T<xRhoa> in BMS "membrane-fractions"
    *** inhibited by: xNckipsd(del(170-249))"dPro" [substitution]
    *** source: 14765113-Fig-3c
  *** xRac1[tAb] GTP-association[BDPD] is increased itpo xPak1(mnr)"CAAX"
    *** cells: COS7<xRac1> in BMS
    *** enhanced by: xArhGef7 [addition]
    *** source: 9659915-Fig-6c
  *** xRac1[tAb] GTP-association[BDPD] is increased itpo xVav2
    *** cells: COS7<xRac1> in BMLS "plated on Fn1"
    *** source: 12198159-Fig-4
  *** xRac1[tAb]IP GTP-association[35S-GTPgS] is unchanged by rRgl1
    *** cells: none
    *** IPfrom: SF9 in BMS "cytosolic-fraction"
    *** source: 9099691-Fig-5
  *** xRac1[tAb]IP GTP-association[35S-GTPgS] is unchanged by rRgl1
    *** cells: none
    *** IPfrom: SF9 in BMS "membrane-fraction"
    *** source: 9099691-Fig-5
  *** xRac1[tAb]IP GTP-association[TLC] is increased itpo xRap1Gds1
    *** cells: COS7 in BMS
    *** comment: results are reported as bound labelled GDP
    *** inhibited by: xRac1(T17N) [substitution]
    *** source: 8990121-Fig-3a
  *** rRac1{GDP} GTP-association[35S-GTPgS] is unchanged by rLck
    *** cells: none
    *** source: 8990121-Fig-1a
  *** rRac1{GDP} GTP-association[35S-GTPgS] is unchanged by rLck
    *** cells: none
    *** source: 10523675-Fig-4b
  *** rRac1{GTPgS} boundby[WB] xMlk3(K144R)[tAb]IP is detectable
    *** cells: none
    *** IP1from: HEK293T in BMS
    *** IP2from: HEK293T in BMS
    *** inhibited by: rRac1{GDP} [substitution]
    *** source: 18851832-Fig-S5
  *** rRac1{GTPgS} boundby[WB] xMlk3(K144R)[tAb]IP is detectable
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** inhibited by: rRac1{GDP} [substitution]
    *** source: 18851832-Fig-S5
  *** rRac1{GTPgS}[32P] boundby[WB] rMekk3[Resin] is undetectable
    *** cells: none
    *** source: 9305638-Fig-7
  *** rRac1{GTPgS}[32P] boundby[WB] rMekk4[Resin] is detectable
    *** cells: none
    *** source: 9305638-Fig-7
  *** rRac1{GTPgS}[35S] boundby[WB] rRgl1(602-768)[Resin] is undetectable
    *** cells: none
    *** inhibited by: rHras{GDP} [substitution]
    *** source: 7498475-Fig-1
  *** rRac2 GDP-dissociation[3H-GDP] is unchanged by rVav1
    *** cells: none
    *** source: 8289830-Fig-2
  *** rRac2 GDP-dissociation[Mant-GDP] is increased by rTiam1(mnr)"DH/PH"
    *** cells: none
    *** source: 17214551-Fig-2b
  *** rRac2 GDP-dissociation[Mant-GDP] is unchanged by rArhGef4(233-448)"DH"
    *** cells: none
    *** source: 17214551-Fig-2b
  *** rRac2 GTP-association[Mant-GTP] is unchanged by rArhGef4(271-632)"DH/PH"
    *** cells: none
    *** source: 17704816-Fig-S1
*** Rac2--
  *** rRac3 GDP-dissociation[Mant-GDP] is increased by rTiam1(mnr)"DH/PH"
    *** cells: none
    *** source: 17214551-Fig-2c
  *** rRac3 GDP-dissociation[Mant-GDP] is unchanged by rArhGef4(233-448)"DH"
    *** cells: none
    *** source: 17214551-Fig-2c
  *** rRac3 GTP-association[Mant-GTP] is unchanged by rArhGef4(271-632)"DH/PH"
    *** cells: none
    *** source: 17704816-Fig-S1
*** Rac3--
*** Rack1--
  *** Rack1[Ab] copptby[WB] TnfR1[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 12361233-Fig-5c
  *** xRack1[tAb] colocwith[IHC] xTnfR1(1-317)"death-domain-mut"[tAb] is detectable
    *** cells: COS1<xFan> in BMS
    *** reqs: xFan [omission]
    *** source: 12361233-Fig-6
  *** xRack1[tAb] colocwith[IHC] xTnfR1(1-317)"death-domain-mut"[tAb] is undetectable
    *** cells: COS1<xFan> in BMS
    *** unaffected by: Tnf (30 min) [stim]
    *** source: 12361233-Fig-6
  *** xRack1[tAb] copptby[WB] xFan[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12361233-Fig-5a
  *** xRad1[tAb] copptby[WB] xRad17[tAb] is detectable
    *** cells: HEK293T<xRad1><xRad17> in BMS
    *** inhibited by: xRad17(S646A/S656A) [substitution]
    *** source: 11418864-Fig-5b
  *** xRad17[phosAb] phos(S646)[phosAb] is detectable
    *** cells: BJ<xRad17> in BMS
    *** inhibited by: xRad17(S646A/S656A) [substitution]
    *** source: 11418864-Fig-4b
  *** xRad17[tAb] copptby[WB] xRad1[tAb] is detectable
    *** cells: HEK293T<xRad1><xRad17> in BMS
    *** inhibited by: xRad17(S646A/S656A) [substitution]
    *** inhibited by: xRad17(S646A) [substitution]
    *** inhibited by: xRad17(S656A) [substitution]
    *** inhibited by: xRad17(S646D/S656D) [substitution]
    *** source: 11418864-Fig-5a
  *** xRad17[tAb]IP phos(S646)[phosAb] is detectable
    *** cells: HEK293T<xRad17> in BMS
    *** inhibited by: xRad17(S646A) [substitution]
    *** unaffected by: xRad17(S656A) [substitution]
    *** source: 11418864-Fig-2b
  *** xRad17[tAb]IP phos(S656)[phosAb] is detectable
    *** cells: HEK293T<xRad17> in BMS
    *** inhibited by: xRad17(S656A) [substitution]
    *** unaffected by: xRad17(S646A) [substitution]
    *** source: 11418864-Fig-2b
*** Rad50--
  *** rRad50[Ab] boundby[WB] sMdc1(325-340){phos(S329/T331)}[biotin] is detectable
    *** cells: none
    *** comment: reaction also contains rNbs1 and rMre11
    *** source: 18583988-Fig-3a
  *** Rad50[Ab] copptby[WB] Atrip[Ab] is detectable
    *** cells: HELA in BMS
    *** source: 16431910-Fig-S1
  *** Rad50[Ab] copptby[WB] Mrc1[Ab] is detectable
    *** cells: HELA in BMS "nuclear-extracts"
    *** source: 12607003-Fig-1c
  *** Rad50[Ab] copptby[WB] xMdc1(197-516/NLS)[tAb] is decreased irt TBB (6 hr)
    *** cells: U2OS<xMdc1(197-516/NLS)> in BMS
    *** source: 18583988-Fig-2e
  *** Rad50[Ab] copptby[WB] xMdc1[tAb] is detectable
    *** cells: HEK293T<xMdc1> in BMS
    *** inhibited by: xMdc1(del(196-506)) [substitution] 
    *** source: 18583988-Fig-4b
  *** Rad50[Ab] snaggedby[WB] dsDNA[biotin] is detectable
    *** cells: NBS1LBI<Nbs1~fmut><xNbs1> in BMS
    *** does not req: xNbs1 [omission]
    *** unaffected by: xNbs1(1-734)"delC" [substitution]
    *** source: 15758953-Fig-2a
  *** Rad50[Ab] snaggedby[WB] rMdc1(296-340){phos}[GST] is detectable
    *** cells: HELA in BMS "nuclear-extract"
    *** comment: rMdc1(296-340) was phosed by rCsnk2
    *** inhibited by: rMdc1(296-340/T301A/T331A) [substitution]
    *** source: 18583988-Fig-2d
  *** Rad50[Ab] snaggedby[WB] rMdc1(296-340){phos}[GST] is detectable
    *** cells: MRC5 in BMS
    *** comment: rMdc1(296-340) was phosed by rCsnk2
    *** inhibited by: rMdc1(296-340) [substitution]
    *** source: 18583988-Fig-3c
  *** Rad50[Ab] snaggedby[WB] rMdc1(296-340){phos}[GST] is detectable
    *** cells: NBS1LBI<Nbs1~fmut><xNbs1> in BMS
    *** comment: rMdc1(296-340) was phosed by rCsnk2
    *** reqs: xNbs1 [omission]
    *** inhibited by: xNbs1(R28A) [substitution]
    *** source: 18583988-Fig-3c
  *** Rad50[Ab] snaggedby[WB] sH2ax(123-143){phos(S140)}[GST] is detectable
    *** cells: HELA in BMS "nuclear-extracts"
    *** inhibited by: sH2ax(123-143) [substitution]
    *** source: 16377563-Fig-1b
  *** Rad50[Ab] snaggedby[WB] sH2ax(134-143){phos(S140)}[biotin] is detectable
    *** cells: HELA in BMS "nuclear-extract"
    *** inhibited by: sH2ax(134-143) [substitution]
    *** source: 18583988-Fig-1c
  *** Rad50[Ab] snaggedby[WB] sH2ax(134-143){phos(S140)}[biotin] is detectable
    *** cells: HELA in BMS "nuclear-extract"
    *** source: 18583988-Fig-2a
  *** Rad50[Ab] snaggedby[WB] sMdc1(325-340){phos(S329/T331)}[biotin] is detectable
    *** cells: HELA in BMS "nuclear-extract"
    *** inhibited by: sMdc1(325-340) [substitution]
    *** source: 18583988-Fig-1c
*** Raf1--
  *** rRaf1(1-149){phos}[Ab] boundby[WB] rHras{GMPPNP}[GST] is detectable
    *** cells: none
    *** enhanced by: rRaf1(1-149){unphos} [substitution]
    *** comment: rRaf1(1-149) was phosphorylated by pPKA
    *** source: 9001246-Fig-4b
  *** rRaf1(1-149){phos}[Ab] boundby[WB] rHras{GMPPNP}[GST] is detectable
    *** cells: none
    *** inhibited by: rHras{GDP} [substitution]
    *** comment: rRaf1(1-149) was phosphorylated by pPKA
    *** source: 9001246-Fig-4b
  *** rRaf1(1-149){phos}[Ab] boundby[WB] rRheb{GMPPNP}[GST] is detectable
    *** cells: none
    *** inhibited by: rRaf1(1-149){unphos} [substitution]
    *** comment: rRaf1(1-149) was phosphorylated by pPKA
    *** source: 9001246-Fig-4b
  *** rRaf1(1-149){phos}[Ab] boundby[WB] rRheb{GMPPNP}[GST] is detectable
    *** cells: none
    *** inhibited by: rRheb{GDP} [substitution]
    *** comment: rRaf1(1-149) was phosphorylated by pPKA
    *** source: 9001246-Fig-4b
  *** xRaf1(1-330)[tAb] copptby[WB] xBraf(437-766)[tAb] is detectable
    *** cells: HEK293<xRaf1(1-330)><xBraf(437-766)> in BMLS
    *** source: 15710605-Fig-5b
  *** xRaf1(del(66-303))"CA"[tAb] copptby[WB] xMek2[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 9808624-Fig-3d
  *** xRaf1(del(66-303))"CA"[tAb]IP IVKA(Mek1)[32P-ATP] is unchanged itpo xBrap
    *** cells: HELA in BMS
    *** source: 14724641-Fig-2a
  *** rRaf1(K375M){phos}[Ab] boundby[WB] rHras{GMPPNP}[GST] is detectable
    *** cells: none
    *** enhanced by: rRaf1(K375M){unphos} [substitution]
    *** comment: rRaf1(K375M) was phosphorylated by pPKA
    *** source: 9001246-Fig-4a
  *** rRaf1(K375M){phos}[Ab] boundby[WB] rHras{GMPPNP}[GST] is detectable
    *** cells: none
    *** inhibited by: rHras{GDP} [substitution]
    *** comment: rRaf1(K375M) was phosphorylated by pPKA
    *** source: 9001246-Fig-4a
  *** rRaf1(K375M){phos}[Ab] boundby[WB] rRheb{GMPPNP}[GST] is detectable
    *** cells: none
    *** inhibited by: rRaf1(K375M){unphos} [substitution]
    *** comment: rRaf1(K375M) was phosphorylated by pPKA
    *** source: 9001246-Fig-4a
  *** rRaf1(K375M){phos}[Ab] boundby[WB] rRheb{GMPPNP}[GST] is detectable
    *** cells: none
    *** inhibited by: rRheb{GDP} [substitution]
    *** comment: rRaf1(K375M) was phosphorylated by pPKA
    *** source: 9001246-Fig-4a
  *** xRaf1(mnr)"BXB"[tAb] copptby[WB] xBraf[tAb] is decreased itpo xBrap
    *** cells: HEK293<xRaf1><xBraf> in BMS
    *** source: 18332145-Fig-3d
  *** xRaf1(mnr)"CAAX"[tAb]IP IVKA(Mek1)(S217/S221)[phosAb] is unchanged itpo xNfkb1(497-968)
    *** cells: HEK293<xRaf1(mnr)"CAAX"> in BMS
    *** unaffected by: xNfkb1(801-892) [substitution]
    *** source: 12832462-Fig-7d
  *** xRaf1(S257L)[Ab]IP IVKA(snr)[32P-ATP] is increased itpo xRras(G38V)"CA"
    *** cells: COS in BMS
    *** source: 12077328-Fig-8a
  *** xRaf1(S259A)[Ab]IP IVKA(snr)[32P-ATP] is increased itpo xRras(G38V)"CA"
    *** cells: COS in BMS
    *** source: 12077328-Fig-8a
  *** rRaf1[35S] boundby[WB] rIkk1[tAb] is detectable
    *** cells: none
    *** source: 10022904-Fig-1a
  *** rRaf1[35S] boundby[WB] rIkk2[tAb] is detectable
    *** cells: none
    *** source: 10022904-Fig-1a
  *** rRaf1[Ab] boundby[WB] rPhb[GST] is detectable
    *** cells: none
    *** source: 16041367-Fig-S4a
  *** Raf1[Ab] copptby[WB] Bag1[Ab] is detectable
    *** cells: OT23 in BMS
    *** source: 11231577-Fig-4c
  *** Raf1[Ab] copptby[WB] Braf[Ab] is decreased itpo xMerlin
    *** cells: RT4<Merlin~null> in BMS
    *** source: 16537381-Fig-4d
  *** Raf1[Ab] copptby[WB] Braf[Ab] is detectable
    *** cells: COS1 in BMLS
    *** inhibited by: xMek1(S218A/S222A)"DN" [addition]
    *** source: 16508002-Fig-5c
  *** xRaf1[Ab] copptby[WB] Braf[Ab] is increased itpo xHras(G12V)"CA"
    *** cells: HEK293 in BMLS
    *** source: 11325826-Fig-1c
  *** Raf1[Ab] copptby[WB] xBraf(D594G)[tAb] is detectable
    *** cells: NIH3T3<xBraf(D594G)> in BMLS
    *** inhibited by: xBraf(D594G/S729A) [substitution]
    *** source: 19933846-Fig-3f
  *** Raf1[Ab] copptby[WB] xBraf(E501G)[tAb] is detectable
    *** cells: NIH3T3<xBraf(E501G)> in BMLS
    *** enhanced by: xBraf(E501G/S151A/S401A/S750A/T753A) [substitution]
    *** source: 19933846-Fig-8a
  *** Raf1[Ab] copptby[WB] xBraf(G466A)[tAb] is detectable
    *** cells: NIH3T3<xBraf(G466A)> in BMLS
    *** inhibited by: xBraf(G466A/S729A) [substitution]
    *** source: 19933846-Fig-3f
  *** Raf1[Ab] copptby[WB] xBraf(S467A)[tAb] is detectable
    *** cells: NIH3T3<xBraf(S467A)> in BMLS
    *** enhanced by: xBraf(S467A/S151A/S401A/S750A/T753A) [substitution]
    *** source: 19933846-Fig-8a
  *** Raf1[Ab] copptby[WB] xBraf(V600E)[tAb] is detectable
    *** cells: NIH3T3<xBraf(V600E)> in BMLS
    *** inhibited by: xBraf(V600E/S729A) [substitution]
    *** source: 19933846-Fig-3f
  *** xRaf1[Ab] copptby[WB] xBraf[Ab] is increased itpo xHras(G12V)"CA"
    *** cells: HEK293 in BMLS
    *** source: 11325826-Fig-1a
  *** xRaf1[Ab] copptby[WB] xBraf[Ab] is increased itpo xHras(G12V)"CA"
    *** cells: HEK293 in BMLS
    *** unaffected by: xHras(G12V/mnr)"membrane-association-mut" [substitution]
    *** source: 11325826-Fig-2
  *** xRaf1[Ab] copptby[WB] xBraf[Ab] is unchanged itpo xRap1a(G12V)"CA"
    *** cells: HEK293 in BMLS
    *** source: 11325826-Fig-2
  *** xRaf1[Ab] copptby[WB] xBraf[tAb] is decreased itpo xBrap
    *** cells: HEK293<xRaf1><xBraf> in BMS
    *** source: 18332145-Fig-2a
  *** Raf1[Ab] copptby[WB] xBraf[tAb] is detectable
    *** cells: NIH3T3<xBraf> in BMLS
    *** enhanced by: xBraf(S151A/S401A/S750A/T753A) [substitution]
    *** source: 19933846-Fig-3c
  *** Raf1[Ab] copptby[WB] xBrap[tAb] is decreased itpo xKsr1
    *** cells: HEK293<xBrap> in BMS
    *** source: 18332145-Fig-4d
  *** xRaf1[Ab] copptby[WB] xPkcz[Ab] is increased itpo xYwhab
    *** cells: COS7 in BMS
    *** enhanced by: xYwhab(S130A) [substitution]
    *** enhanced by: xYwhab(T141A) [substitution]
    *** source: 10620507-Fig-8
  *** xRaf1[Ab] copptby[WB] xPkcz[Ab] is increased itpo xYwhab
    *** cells: COS7 in BMS
    *** inhibited by: xPkcz(S186A) [substitution]
    *** source: 10620507-Fig-4
  *** xRaf1[Ab] copptby[WB] xPkcz[Ab] is increased itpo xYwhab
    *** cells: COS7 in BMS
    *** source: 10620507-Fig-5
  *** Raf1[Ab] copptby[WB] xPpp2r1?[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 10801873-Fig-4a
  *** Raf1[Ab] copptby[WB] xRin1(Q78L)[GST] is detectable
    *** cells: COS<xRin1(Q78L)> in BMS
    *** source: 16157584-Fig-5c
  *** xRaf1[Ab] copptby[WB] xYwhab[tAb] is detectable
    *** cells: HEK293T<xYwhab><xRaf1> in BMS
    *** source: 12177059-Fig-1c
  *** xRaf1[Ab] copptby[WB] xYwhaq[GST] is detectable
    *** cells: HEK293T<xYwhaq><xRaf1> in BMS
    *** source: 12177059-Fig-1f
  *** xRaf1[Ab] copptby[WB] xYwhaq[tAb] is detectable
    *** cells: HEK293T<xYwhaq><xRaf1> in BMS
    *** inhibited by: xYwhaq(R56A/R60A) [substitution]
    *** inhibited by: xYwhaq(R127A) [substitution]
    *** source: 12177059-Fig-2a
  *** xRaf1[Ab] copptby[WB] xYwhaq[tAb] is detectable
    *** cells: HEK293T<xYwhaq><xRaf1> in BMS
    *** source: 12177059-Fig-1c
  *** xRaf1[Ab] copptby[WB] xYwhaz[tAb] is detectable
    *** cells: HEK293T<xYwhaz><xRaf1> in BMS
    *** source: 12177059-Fig-1c
  *** xRaf1[Ab] phos(S338)[phosAb-ppt] is increased itpo xPak3(mnr)"CA"
    *** cells: COS7 in BMS
    *** source: 9823899-Fig-4d
  *** xRaf1[Ab]IP IVKA(Mek?,Erk2)(TEY)[phosAb] is detectable
    *** cells: SF9<xRaf1> in BMS
    *** enhanced by: xRaf1(S259A) [substitution]
    *** inhibited by: xRaf1(S621A) [substitution]
    *** partially inhibited by: xRaf1(S259A/S621A) [substitution]
    *** source: 14688280-Fig-4b
  *** xRaf1[Ab]IP IVKA(Mek?,Erk2)(TEY)[phosAb] is increased itpo (xHras(G12V) + xLck)
    *** cells: SF9<xRaf1> in BMS
    *** inhibited by: xRaf1(R89L/K375W) [substitution]
    *** unaffected by: xRaf1(S621A) [substitution]
    *** source: 14688280-Fig-1a
  *** Raf1[Ab]IP IVKA(Mek?)[32P-ATP] is detectable
    *** cells: NIH3T3<xBraf> in BMS
    *** unaffected by: xBraf(S729A) [substitution]
    *** enhanced by: xBraf(S151A/S401A/S750A/T753A) [substitution]
    *** enhanced by: xBraf(V600E) [substitution]
    *** enhanced by: xBraf(V600E/S151A/S401A/S750A/T753A) [substitution]
    *** enhanced by: xBraf(V600E/S729A) [substitution]
    *** enhanced by: xBraf(G469A) [substitution]
    *** enhanced by: xBraf(G469A/S151A/S401A/S750A/T753A) [substitution]
    *** enhanced by: xBraf(G469A/S729A) [substitution]
    *** enhanced by: xBraf(G464V) [substitution]
    *** enhanced by: xBraf(G464V/S151A/S401A/S750A/T753A) [substitution]
    *** enhanced by: xBraf(G464V/S729A) [substitution]
    *** enhanced by: xBraf(L597V) [substitution]
    *** enhanced by: xBraf(L597V/S151A/S401A/S750A/T753A) [substitution]
    *** enhanced by: xBraf(L597V/S729A) [substitution]
    *** enhanced by: xBraf(G466A) [substitution]
    *** enhanced by: xBraf(G466A/S151A/S401A/S750A/T753A) [substitution]
    *** enhanced by: xBraf(G466A/S729A) [substitution]
    *** enhanced by: xBraf(G466V) [substitution]
    *** enhanced by: xBraf(G466V/S151A/S401A/S750A/T753A) [substitution]
    *** enhanced by: xBraf(G466V/S729A) [substitution]
    *** enhanced by: xBraf(D594G) [substitution]
    *** enhanced by: xBraf(D594G/S151A/S401A/S750A/T753A) [substitution]
    *** enhanced by: xBraf(D594G/S729A) [substitution]
    *** source: 19933846-Fig-5b
  *** Raf1[Ab]IP IVKA(Mek1)[32P-ATP] is increased itpo xBag1
    *** cells: OT23 in BMS
    *** unaffected by: xHras(S17N)"DN" [addition]
    *** inhibited by: xHspa1a [addition]
    *** source: 11231577-Fig-3
  *** xRaf1[Ab]IP IVKA(snr)[32P-ATP] is increased itpo (xHras(G12V)"CA" + xSrc(Y527F)"CA")
    *** cells: COS in BMS
    *** inhibited by: xRaf1(S621A) [substitution]
    *** source: 12077328-Fig-2a
  *** xRaf1[Ab]IP IVKA(snr)[32P-ATP] is increased itpo xPak3(mnr)"CA"
    *** cells: COS7 in BMS
    *** source: 9823899-Fig-4c
  *** xRaf1[Ab]IP IVKA(snr)[32P-ATP] is increased itpo xRras2(G23V)"CA"
    *** cells: COS in BMS
    *** enhanced by: xRaf1(S257L) [substitution]
    *** enhanced by: xRaf1(S259A) [substitution]
    *** source: 12077328-Fig-8a
  *** xRaf1[Ab]IP IVKA(snr)[32P-ATP] is increased itpo xSrc(mnr)"CA"
    *** cells: COS7 in BMS
    *** inhibited by: xRaf1(S338A/S339A) [substitution]
    *** source: 9234708-Fig-7
  *** xRaf1[Ab]IP IVKA(snr)[32P-ATP] is unchanged itpo xRras(G38V)"CA"
    *** cells: COS in BMS
    *** source: 12077328-Fig-8a
  *** xRaf1[Ab]IP phos(S338)[phosAb] is increased itpo xPak1(165-544)"CA"
    *** cells: HEK293 in BMLS
    *** source: 11948406-Fig-1a
  *** xRaf1[Ab]IP phos[WBMS] is increased by rErk2(mnr)"CA"
    *** cells: NIH3T3 in BMLS
    *** inhibited by: xRaf1(S29A/S289A/S296A/S301A/S642A) [substitution]
    *** comment: xRaf1 is phosed[HPLC-PAA-ED] on S29A/S289A/S296A/S301A/S642A
    *** source: 15664191-Fig-3b
  *** xRaf1[Ab]IP phos[WBMS] is unchanged by rCdk1(mnr)"CA"
    *** cells: NIH3T3 in BMLS
    *** source: 15664191-Fig-3b
  *** xRaf1[Ab]IP phos[WBMS] is unchanged by rGsk3?(mnr)"CA"
    *** cells: NIH3T3 in BMLS
    *** source: 15664191-Fig-3b
  *** xRaf1[GST]IP IVKA(Mek1,Erk2,MBP)[32P-ATP] is unchanged itpo xRin1
    *** cells: COS<xRaf1> in BMS
    *** unaffected by: xRin1(Q68L) [substitution]
    *** unaffected by: xRin1(S34N) [substitution]
    *** source: 16157584-Fig-5d
  *** xRaf1[GST]IP IVKA(Mek1,Erk2,MBP)[32P-ATP] is unchanged itpo xRit1(Q79L)"CA"
    *** cells: COS in BMLS
    *** unaffected by: xRit1(WT) [substitution]
    *** unaffected by: xRit1(S35N) [substitution]
    *** source: 15632082-Fig-4c
  *** xRaf1[GST]IP phos(S338)[phosAb] is increased itpo xRin1(Q68L)
    *** cells: COS<xRaf1> in BMS
    *** inhibited by: xRin1 [substitution]
    *** inhibited by: xRin1(S34N) [substitution]
    *** source: 16157584-Fig-5d
  *** Raf1[phosAb] phos(S259)[phosAb] is increased itao Phb [RNAi]
    *** cells: HELA in BMLS
    *** source: 16041367-Fig-3c,5a
  *** xRaf1[phosAb] phos(S259)[phosAb] is increased itpo xAkt1(mnr)"CA"
    *** cells: COS1 in BMS
    *** unaffected by: xRaf1(R89L)"Ras-binding-mut" [substitution]
    *** unaffected by: xRaf1(C168S)"Zinc-finger-mut" [substitution]
    *** source: 15711535-Fig-1d
  *** Raf1[phosAb] phos(S338)[phosAb] is detectable
    *** cells: HELA in BMLS
    *** partially reqs: Phb [RNAi]
    *** source: 16041367-Fig-5b
  *** Raf1[phosAb] phos(S338)[phosAb] is detectable
    *** cells: HELA in BMLS
    *** reqs: Phb [RNAi]
    *** source: 16041367-Fig-3c
  *** xRaf1[phosAb] phos(S621)[phosAb] is detectable-but unchanged itpo (xHras(G12V) + xLck)
    *** cells: SF9<xRaf1> in BMS
    *** inhibited by: xRaf1(R89L/K375W) [substitution]
    *** inhibited by: xRaf1(S621A) [substitution]
    *** source: 14688280-Fig-1a
  *** rRaf1[tAb] boundby[WB] rBraf[tAb] is increased by rYwhaz
    *** cells: none
    *** inhibited by: rYwhaz(E5K/L12Q/A13Q/E14R/Y82Q/K85N/E87Q)"dimerization-mut" [substitution]
    *** source: 16508002-Fig-4b
  *** rRaf1[tAb] boundby[WB] rHras(G12V){GTPgS}[GST] is detectable
    *** cells: none
    *** inhibited by: rHras(G12V){GDP} [substitution]
    *** source: 15854902-Fig-S4
  *** rRaf1[tAb] boundby[WB] rRheb{GTPgS}[GST] is detectable
    *** cells: none
    *** enhanced by: rRheb{GDP} [substitution]
    *** source: 15854902-Fig-S4
  *** rRaf1[tAb] boundby[WB] rRheb{NucFree}[GST] is detectable
    *** cells: none
    *** partially inhibited by: rRheb{GDP} [substitution]
    *** inhibited by: rRheb{GMPPNP} [substitution]
    *** source: 15854902-Fig-5a
  *** xRaf1[tAb] copptby[WB] Braf[Ab] is detectable
    *** cells: HEK293 in BMLS
    *** inhibited by: xRheb [addition]
    *** unaffected by: Rapamycin [addition]
    *** source: 16803888-Fig-2b
  *** xRaf1[tAb] copptby[WB] xBraf[tAb] is increased itpo xYwhaz
    *** cells: COS1 in BMLS
    *** source: 16508002-Fig-4a
  *** xRaf1[tAb] copptby[WB] xKsr1[tAb] is decreased itpo xBrap
    *** cells: HEK293<xRaf1><xKsr1> in BMS
    *** source: 18332145-Fig-4c
  *** xRaf1[tAb] copptby[WB] xMek1[tAb] is detectable
    *** cells: HELA<xRaf1><xMek1> in BMS
    *** inhibited by: xMek1(M308A/I310A) [substitution]
    *** source: 19541618-Fig-S1c
  *** xRaf1[tAb] copptby[WB] xMek1[tAb] is detectable
    *** cells: HELA<xRaf1><xMek1> in BMS
    *** unaffected by: xRaf1(C588Y) [substitution]
    *** source: 19541618-Fig-S1c
  *** xRaf1[tAb] copptby[WB] xMek2[tAb] is detectable
    *** cells: HELA<xRaf1><xMek2> in BMS
    *** inhibited by: xMek2(M316A/I318A) [substitution]
    *** source: 19541618-Fig-S1c
  *** xRaf1[tAb] copptby[WB] xMlk3[tAb] is decreased itpo xMerlin
    *** cells: HEK293 in BMS
    *** source: 16537381-Fig-4c
  *** xRaf1[tAb] copptby[WB] xRin1(Q78L)[GST] is detectable
    *** cells: COS<xRaf1><xRin1(Q78L)> in BMS
    *** source: 16157584-Fig-5a
  *** xRaf1[tAb] infraction(membrane)[WB] is unchanged itpo xPak3(mnr)"CA"
    *** cells: COS in BMS
    *** source: 11259591-Fig-8d
  *** xRaf1[tAb]IP IVKA(Erk?)[32P-ATP] is increased itpo xRasGrf1
    *** cells: COS7 in BMLS
    *** source: 11395506-Fig-5b
  *** xRaf1[tAb]IP IVKA(Erk?)[32P-ATP] is unchanged itpo xPlce1
    *** cells: COS7 in BMLS
    *** source: 11395506-Fig-5b
  *** xRaf1[tAb]IP IVKA(Erk?)[32P-ATP] is unchanged itpo xRapGef2
    *** cells: COS7 in BMLS
    *** source: 11395506-Fig-5b
  *** xRaf1[tAb]IP IVKA(Erk2)[32P-ATP] is unchanged itpo xRap1a(G12V)"CA"
    *** cells: COS7 in BMS
    *** source: 9867809-Fig-3a
  *** xRaf1[tAb]IP IVKA(Mek?,Erk?,MBP)[32P-ATP] is increased itpo xBraf(G466E)"CA"
    *** cells: COS7 in BMS
    *** enhanced by: U0126 [addition] no-bkg-control
    *** source: 16364920-Fig-1b
  *** xRaf1[tAb]IP IVKA(Mek?,Erk?,MBP)[32P-ATP] is increased itpo xBraf(G466E)"CA"
    *** cells: COS7 in BMS
    *** inhibited by: xBraf(G466V/K483M)"KD" [substitution] no-bkg-control
    *** source: 16364920-Fig-1a
  *** xRaf1[tAb]IP IVKA(Mek?,Erk?,MBP)[32P-ATP] is increased itpo xBraf(G466E)"CA"
    *** cells: COS7 in BMS
    *** inhibited by: xBraf(G466V/K483M)"KD" [substitution] no-bkg-control
    *** source: 16364920-Fig-1b
  *** xRaf1[tAb]IP IVKA(Mek?,Erk?,MBP)[32P-ATP] is increased itpo xBraf(G466E)"CA"
    *** cells: COS7 in BMS
    *** source: 16364920-Fig-S1
  *** xRaf1[tAb]IP IVKA(Mek?,Erk?,MBP)[32P-ATP] is increased itpo xBraf(G466R)"CA"
    *** cells: COS7 in BMS
    *** source: 16364920-Fig-S1
  *** xRaf1[tAb]IP IVKA(Mek?,Erk?,MBP)[32P-ATP] is increased itpo xBraf(G466V)"CA"
    *** cells: COS7 in BMS
    *** inhibited by: xRaf1(S621A) [substitution]
    *** source: 16364920-Fig-3d
  *** xRaf1[tAb]IP IVKA(Mek?,Erk?,MBP)[32P-ATP] is increased itpo xBraf(G466V)"CA"
    *** cells: COS7 in BMS
    *** inhibited by: xRaf1(T491A/S494A) [substitution]
    *** source: 16364920-Fig-3d
  *** xRaf1[tAb]IP IVKA(Mek?,Erk?,MBP)[32P-ATP] is increased itpo xBraf(G466V)"CA"
    *** cells: COS7 in BMS
    *** partially inhibited by: xRaf1(S338A) [substitution]
    *** source: 16364920-Fig-3b
  *** xRaf1[tAb]IP IVKA(Mek?,Erk?,MBP)[32P-ATP] is increased itpo xBraf(G466V)"CA"
    *** cells: COS7 in BMS
    *** partially inhibited by: xRaf1(Y341A) [substitution]
    *** source: 16364920-Fig-3a
  *** xRaf1[tAb]IP IVKA(Mek?,Erk?,MBP)[32P-ATP] is increased itpo xBraf(G466V)"CA"
    *** cells: COS7 in BMS
    *** source: 16364920-Fig-S1
  *** xRaf1[tAb]IP IVKA(Mek?,Erk?,MBP)[32P-ATP] is increased itpo xBraf(G594R)"CA"
    *** cells: COS7 in BMS
    *** inhibited by: xBraf(G466V/K483M)"KD" [substitution] no-bkg-control
    *** source: 16364920-Fig-1a
  *** xRaf1[tAb]IP IVKA(Mek?,Erk?,MBP)[32P-ATP] is increased itpo xBraf(G598R)"CA"
    *** cells: COS7 in BMS
    *** inhibited by: xRaf1(S621A) [substitution]
    *** source: 16364920-Fig-3e
  *** xRaf1[tAb]IP IVKA(Mek?,Erk?,MBP)[32P-ATP] is increased itpo xBraf(G598R)"CA"
    *** cells: COS7 in BMS
    *** inhibited by: xRaf1(T491A/S494A) [substitution]
    *** source: 16364920-Fig-3d
  *** xRaf1[tAb]IP IVKA(Mek?,Erk?,MBP)[32P-ATP] is increased itpo xBraf(G598R)"CA"
    *** cells: COS7 in BMS
    *** partially inhibited by: xRaf1(S338A) [substitution]
    *** source: 16364920-Fig-3b
  *** xRaf1[tAb]IP IVKA(Mek?,Erk?,MBP)[32P-ATP] is increased itpo xBraf(G598R)"CA"
    *** cells: COS7 in BMS
    *** partially inhibited by: xRaf1(Y341A) [substitution]
    *** source: 16364920-Fig-3a
  *** xRaf1[tAb]IP IVKA(Mek?,Erk?,MBP)[32P-ATP] is increased itpo xBraf(V600E)"CA"
    *** cells: COS7 in BMS
    *** source: 16364920-Fig-S1
  *** xRaf1[tAb]IP IVKA(Mek?,Erk?,MBP)[32P-ATP] is increased itpo xHras(G12V)"CA"
    *** cells: COS in BMS
    *** synergistically enhanced by: xSrc(Y527F)"CA" [addition]
    *** source: 11259591-Fig-7a,7b
  *** xRaf1[tAb]IP IVKA(Mek?,Erk?,MBP)[32P-ATP] is increased itpo xSrc(Y527F)"CA"
    *** cells: COS in BMS
    *** synergistically enhanced by: xHras(G12V)"CA" [addition]
    *** source: 11259591-Fig-7a,7b
  *** xRaf1[tAb]IP IVKA(Mek?,Erk?,MBP)[32P-ATP] is increased itpo xSrc(Y527F)"CA"
    *** cells: COS in BMS
    *** unaffected by: xCdc42(G12V)"CA" [addition]
    *** unaffected by: xPak3(mnr)"CA" [addition]
    *** unaffected by: xPak3(mnr)"KD" [addition]
    *** source: 11259591-Fig-7a,7b
  *** xRaf1[tAb]IP IVKA(Mek?,Erk?,MBP)[32P-ATP] is unchanged itpo xBraf
    *** cells: COS7 in BMS
    *** source: 16364920-Fig-S1
  *** xRaf1[tAb]IP IVKA(Mek?,Erk?,MBP)[32P-ATP] is unchanged itpo xCdc42(G12V)"CA"
    *** cells: COS in BMS
    *** source: 11259591-Fig-7a
  *** xRaf1[tAb]IP IVKA(Mek?,Erk?,MBP)[32P-ATP] is unchanged itpo xPak3(mnr)"CA"
    *** cells: COS in BMS
    *** source: 11259591-Fig-7b,8e
  *** xRaf1[tAb]IP IVKA(Mek1,Erk1,Elk1)[32P-ATP] is unchanged itpo xShoc2
    *** cells: HEK293 in BMLS
    *** source: 10783161-Fig-2c
  *** xRaf1[tAb]IP IVKA(Mek1,Erk2,MBP)[32P-ATP] is increased itpo (xHras(G12R)"CA" + xSrc(Y527F)"CA")
    *** cells: COS in BMS
    *** inhibited by: xRaf1(S338A) [substitution]
    *** source: 10205168-Fig-1a
  *** xRaf1[tAb]IP IVKA(Mek1,Erk2,MBP)[32P-ATP] is increased itpo (xHras(G12R)"CA" + xSrc(Y527F)"CA")
    *** cells: COS in BMS
    *** inhibited by: xRaf1(Y341A) [substitution]
    *** inhibited by: xRaf1(Y341F) [substitution]
    *** source: 10205168-Fig-1a
  *** xRaf1[tAb]IP IVKA(Mek1,Erk2,MBP)[32P-ATP] is increased itpo (xHras(G12R)"CA" + xSrc(Y527F)"CA")
    *** cells: COS in BMS
    *** unaffected by: xRaf1(S339A) [substitution]
    *** source: 10205168-Fig-1a
  *** xRaf1[tAb]IP IVKA(Mek1,Erk2,MBP)[32P-ATP] is increased itpo (xHras(G12R)"CA" + xSrc(Y527F)"CA")
    *** cells: COS in BMS
    *** unaffected by: xRaf1(Y340A) [substitution]
    *** partially inhibited by: xRaf1(Y340F) [substitution]
    *** source: 10205168-Fig-1a
  *** xRaf1[tAb]IP IVKA(Mek1,Erk2,MBP)[32P-ATP] is increased itpo xHras(G12R)"CA"
    *** cells: COS in BMS
    *** synergistically enhanced by: xSrc(Y527F)"CA" [addition]
    *** source: 10205168-Fig-3a
  *** xRaf1[tAb]IP IVKA(Mek1,Erk2,MBP)[32P-ATP] is increased itpo xHras(G12R)"CA"
    *** cells: COS7 in BMS
    *** synergistically enhanced by: xSrc(Y527F)"CA" [addition]
    *** source: 9020159-Fig-2b
  *** xRaf1[tAb]IP IVKA(Mek1,Erk2,MBP)[32P-ATP] is increased itpo xSrc(Y527F)"CA"
    *** cells: COS in BMS
    *** inhibited by: xRaf1(R89L)"Ras-binding-mut" [substitution]
    *** source: 10205168-Fig-3a
  *** xRaf1[tAb]IP IVKA(Mek1,Erk2,MBP)[32P-ATP] is increased itpo xSrc(Y527F)"CA"
    *** cells: COS in BMS
    *** inhibited by: xRaf1(S338A) [substitution]
    *** source: 10205168-Fig-3c
  *** xRaf1[tAb]IP IVKA(Mek1,Erk2,MBP)[32P-ATP] is increased itpo xSrc(Y527F)"CA"
    *** cells: COS in BMS
    *** inhibited by: xRaf1(Y341A) [substitution]
    *** source: 10205168-Fig-3c
  *** xRaf1[tAb]IP IVKA(Mek1,Erk2,MBP)[32P-ATP] is increased itpo xSrc(Y527F)"CA"
    *** cells: COS in BMS
    *** synergistically enhanced by: xHras(G12R)"CA" [addition]
    *** source: 10205168-Fig-3a
  *** xRaf1[tAb]IP IVKA(Mek1,Erk2,MBP)[32P-ATP] is increased itpo xSrc(Y527F)"CA"
    *** cells: COS7 in BMS
    *** synergistically enhanced by: xHras(G12R)"CA" [addition]
    *** source: 9020159-Fig-2b
  *** xRaf1[tAb]IP IVKA(Mek1,Erk2,MBP)[32P-ATP] is unchanged itpo xRras(G38V)"CA"
    *** cells: COS7 in BMS
    *** source: 8999998-Fig-2a
  *** xRaf1[tAb]IP IVKA(Mek1,Erk2)[32P-ATP] is increased itpo xRit1(Q79L)"CA"
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1a
  *** xRaf1[tAb]IP IVKA(Mek1,Erk2)[32P-ATP] is unchanged itpo xMlk3
    *** cells: COS7 in BMLS
    *** source: 12738796-Fig-1c
  *** xRaf1[tAb]IP IVKA(Mek1,Erk2)[32P-ATP] is unchanged itpo xMlk3(K144A)"KD"
    *** cells: COS7 in BMLS
    *** source: 12738796-Fig-1c
  *** xRaf1[tAb]IP IVKA(Mek1,Erk2)[32P-ATP] is unchanged itpo xRap1a(G12V)"CA"
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1a
  *** xRaf1[tAb]IP IVKA(Mek1,Erk2)[32P-ATP] is unchanged itpo xRap2a(G12V)"CA"
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1a
  *** xRaf1[tAb]IP IVKA(Mek1,Erk2)[32P-ATP] is unchanged itpo xRheb(Q64L)"CA"
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1a
  *** xRaf1[tAb]IP IVKA(Mek1,Erk2)[32P-ATP] is unchanged itpo xRin1(A78L)"CA"
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1a
  *** xRaf1[tAb]IP IVKA(Mek1,Erk2)[32P-ATP] is unchanged itpo xRras(G12V)"CA"
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-1a
  *** xRaf1[tAb]IP IVKA(Mek1)[32P-ATP] is increased itpo xPak1(165-544)"CA"
    *** cells: HEK293 in BMLS
    *** unaffected by: xHras(G15A)"DN" [addition]
    *** source: 9351825-Fig-5c
  *** xRaf1[tAb]IP IVKA(Mek1)[32P-ATP] is increased itpo xRac2(G12V)"CA"
    *** cells: HEK293 in BMLS
    *** unaffected by: xHras(G15A)"DN" [addition]
    *** source: 9351825-Fig-5c
  *** xRaf1[tAb]IP IVKA(Mek1)[32P-ATP] is unchanged itpo xRap1a(G12V)"CA"
    *** cells: COS7 in BMLS
    *** source: 9094716-Fig-5c
  *** xRaf1[tAb]IP IVKA(Mek2,Erk2,MBP)[32P-ATP] is increased itpo xHras(G12R)"CA"
    *** cells: COS7 in BMS
    *** synergistically enhanced by: xSrc(Y527F)"CA" [addition]
    *** source: 9020159-Fig-2b
  *** xRaf1[tAb]IP IVKA(Mek2,Erk2,MBP)[32P-ATP] is increased itpo xSrc(Y527F)"CA"
    *** cells: COS7 in BMS
    *** synergistically enhanced by: xHras(G12R)"CA" [addition]
    *** source: 9020159-Fig-2b
  *** xRaf1[tAb]IP phos(S338)[phosAb] is increased itao Rheb [RNAi]
    *** cells: HEK293 in BMLS
    *** source: 16803888-Fig-1e
  *** xRaf1[tAb]IP phos(S338)[phosAb] is increased itpo (xHras(G12R)"CA" + xSrc(Y527F)"CA")
    *** cells: COS in BMS
    *** inhibited by: xRaf1(Y341A) [substitution]
    *** inhibited by: xRaf1(S338A) [substitution]
    *** unaffected by: xRaf1(S339A) [substitution]
    *** unaffected by: xRaf1(Y340A) [substitution]
    *** source: 10205168-Fig-5a
  *** xRaf1[tAb]IP phos(S338)[phosAb] is increased itpo xBraf(G466V)"CA"
    *** cells: COS7 in BMS
    *** source: 16364920-Fig-3c
  *** xRaf1[tAb]IP phos(S338)[phosAb] is increased itpo xBraf(G596R)"CA"
    *** cells: COS7 in BMS
    *** source: 16364920-Fig-3c
  *** xRaf1[tAb]IP phos(S338)[phosAb] is increased itpo xBraf(V600E)"CA"
    *** cells: COS7 in BMS
    *** source: 16364920-Fig-3c
  *** xRaf1[tAb]IP phos(S338)[phosAb] is increased itpo xHras(G12R)"CA"
    *** cells: COS in BMS
    *** enhanced by: xSrc(Y527F)"CA" [addition]
    *** source: 10205168-Fig-3b
  *** xRaf1[tAb]IP phos(S338)[phosAb] is increased itpo xHras(G12V)"CA"
    *** cells: COS in BMS
    *** synergistically enhanced by: xSrc(Y527F)"CA" [addition]
    *** source: 11259591-Fig-6a
  *** xRaf1[tAb]IP phos(S338)[phosAb] is increased itpo xHras(G12V)"CA"
    *** cells: COS in BMS
    *** synergistically enhanced by: xSrc(Y527F)"CA" [addition]
    *** source: 11259591-Fig-8a
  *** xRaf1[tAb]IP phos(S338)[phosAb] is increased itpo xPak3(mnr)"CA"
    *** cells: COS in BMS
    *** source: 11259591-Fig-6b
  *** xRaf1[tAb]IP phos(S338)[phosAb] is increased itpo xSrc(Y527F)"CA"
    *** cells: COS in BMS
    *** enhanced by: xHras(G12R)"CA" [addition]
    *** source: 10205168-Fig-3b
  *** xRaf1[tAb]IP phos(S338)[phosAb] is increased itpo xSrc(Y527F)"CA"
    *** cells: COS in BMS
    *** inhibited by: xRaf1(R89L)"Ras-binding-mut" [substitution]
    *** source: 10205168-Fig-3b
  *** xRaf1[tAb]IP phos(S338)[phosAb] is increased itpo xSrc(Y527F)"CA"
    *** cells: COS in BMS
    *** inhibited by: xRaf1(R89L)"Ras-binding-mut" [substitution]
    *** source: 11259591-Fig-8a
  *** xRaf1[tAb]IP phos(S338)[phosAb] is increased itpo xSrc(Y527F)"CA"
    *** cells: COS in BMS
    *** source: 10205168-Fig-3b
  *** xRaf1[tAb]IP phos(S338)[phosAb] is increased itpo xSrc(Y527F)"CA"
    *** cells: COS in BMS
    *** source: 11259591-Fig-6a
  *** xRaf1[tAb]IP phos(S338)[phosAb] is increased itpo xSrc(Y527F)"CA"
    *** cells: COS in BMS
    *** source: 11259591-Fig-8a
  *** xRaf1[tAb]IP phos(S338)[phosAb] is increased itpo xSrc(Y527F)"CA"
    *** cells: COS in BMS
    *** synergistically enhanced by: xHras(G12V)"CA" [addition]
    *** source: 11259591-Fig-6a
  *** xRaf1[tAb]IP phos(S338)[phosAb] is increased itpo xSrc(Y527F)"CA"
    *** cells: COS in BMS
    *** synergistically enhanced by: xHras(G12V)"CA" [addition]
    *** source: 11259591-Fig-8a
  *** xRaf1[tAb]IP phos(S338)[phosAb] is increased itpo xSrc(Y527F)"CA"
    *** cells: COS in BMS
    *** unaffected by: xCdc42(G12V)"CA" [addition]
    *** source: 11259591-Fig-6a
  *** xRaf1[tAb]IP phos(S338)[phosAb] is unchanged itpo xBraf
    *** cells: COS7 in BMS
    *** source: 16364920-Fig-3c
  *** xRaf1[tAb]IP phos(S338)[phosAb] is unchanged itpo xCdc42(G12V)"CA"
    *** cells: COS in BMS
    *** source: 11259591-Fig-6a
  *** xRaf1[tAb]IP phos(S338)[phosAb] is unchanged itpo xCdc42(G12V)"CA"
    *** cells: COS in BMS
    *** source: 11259591-Fig-6a,8a
  *** xRaf1[tAb]IP phos(S338)[phosAb] is unchanged itpo xRit1(Q79L)"CA"
    *** cells: COS in BMS
    *** source: 15632082-Fig-4a
*** RagA--
  *** xRagA[tAb]IP GTP-association[32P-GTP] is detectable
    *** cells: HEK293<xRagA> in BMS
    *** inhibited by: xRagA(T21N)"GDP" [substitution]
    *** unaffected by: xRagA(Q66L)"GTP" [substitution]
    *** source: 18604198-Fig-S1
*** RagB--
*** RagC--
  *** rRala GDP-dissociation[3H-GDP] is unchanged by rPlce1
    *** cells: none
    *** source: 11395506-Fig-3
  *** rRala GDP-dissociation[3H-GDP] is unchanged by rRapGef1
    *** cells: none
    *** source: 8524240-Fig-2a
  *** rRala GDP-dissociation[3H-GDP] is unchanged by rRasGrf1
    *** cells: none
    *** source: 8524240-Fig-2b
  *** rRala GDP-dissociation[3H-GDP] is unchanged by rSos1(601-1019)
    *** cells: none
    *** source: 8493579-Fig-1d
  *** rRala GDP-dissociation[3H-GDP] is unchanged by rVav1{Yphos}
    *** cells: none
    *** unaffected by: rVav1 [substitution]
    *** comment: rVav1 was phosphorylated by rLck
    *** source: 8289830-Fig-2
  *** rRala GTP-association[32P-GTP] is unchanged by rSos1(601-1019)
    *** cells: none
    *** source: 8493579-Fig-1e
*** rRala--
*** Rala--
  *** Rala[Ab] GTP-association[BDPD] is detectable
    *** cells: mEFs in BMLS
    *** unaffected by: Tsc2 [KO]
    *** source: 12820960-Fig-1a
  *** Rala[Ab] GTP-association[BDPD] is increased itpo xHras(G12R)"CA"
    *** cells: NIH3T3 in BMLS
    *** source: 11340168-Fig-8a
  *** Rala[Ab] GTP-association[BDPD] is increased itpo xHras(G12V)"CA"
    *** cells: C2C12 in BMLS
    *** enhanced by: A23187 [addition]
    *** source: 10848592-Fig-6c
  *** Rala[Ab] GTP-association[BDPD] is increased itpo xHras(G12V)"CA"
    *** cells: NIH3T3 in BMLS
    *** source: 11340168-Fig-9a
  *** Rala[Ab] GTP-association[BDPD] is increased itpo xHras(Q61L)"CA"
    *** cells: NIH3T3 in BMS
    *** source: 11788587-Fig-4a
  *** Rala[Ab] GTP-association[BDPD] is increased itpo xPdpk1
    *** cells: HEK293 in BMLS
    *** unaffected by: xPdpk1(K11N)"KD" [substitution]
    *** unaffected by: rPdpk1(mnr)"PH-domain-mut" [substitution]
    *** inhibited by: rPdpk1(del(1-50))"Cterm-mut" [substitution]
    *** source: 11889038-Fig-5b
  *** Rala[Ab] GTP-association[BDPD] is increased itpo xPdpk1(mnr)"CA"
    *** cells: HEK293 in BMS
    *** source: 11889038-Fig-2a
  *** Rala[Ab] GTP-association[BDPD] is increased itpo xPik3c?(mnr)"CAAX"
    *** cells: HEK293 in BMS
    *** source: 11889038-Fig-2a
  *** xRala[Ab] GTP-association[BDPD] is increased itpo xRit1(Q79L)"CA"
    *** cells: HEK293 in BMS
    *** inhibited by: xRit1 [substitution]
    *** inhibited by: xRit1(Q79L/Y58C) [substitution]
    *** source: 10869344-Fig-8
  *** Rala[Ab] GTP-association[BDPD] is increased itpo xRit1(Q79L)"CA"
    *** cells: HEK293 in BMS
    *** source: 10869344-Fig-9
  *** Rala[Ab] GTP-association[BDPD] is increased itpo xRras2(G23V)"CA"
    *** cells: NIH3T3 in BMLS
    *** inhibited by: xRras2(G23V/E46S) [substitution]
    *** unaffected by: xRras2(G23V/E48G) [substitution]
    *** source: 11340168-Fig-9b
  *** Rala[Ab] GTP-association[BDPD] is increased itpo xRras2(G23V)"CA"
    *** cells: NIH3T3 in BMLS
    *** source: 11340168-Fig-8a
  *** Rala[Ab] GTP-association[BDPD] is increased itpo xRras2(G23V)"CA"
    *** cells: NIH3T3 in BMLS
    *** source: 11340168-Fig-9a
  *** Rala[Ab] GTP-association[BDPD] is unchanged itpo xAkt1(mnr)"CAAX"
    *** cells: HEK293 in BMS
    *** source: 11889038-Fig-2a
  *** Rala[Ab] GTP-association[BDPD] is unchanged itpo xRras2(Q72L)"CA"
    *** cells: NIH3T3 in BMS
    *** source: 11788587-Fig-4a
  *** xRala[GST]IP GTP-association[TLC] is unchanged itpo xAkt1(mnr)"CAAX"
    *** cells: HEK293 in BMS
    *** source: 11889038-Fig-3a
  *** xRala[GST]IP GTP-association[TLC] is unchanged itpo xPdpk1(mnr)"CA"
    *** cells: HEK293 in BMS
    *** source: 11889038-Fig-3a
  *** xRala[GST]IP GTP-association[TLC] is unchanged itpo xPik3c?(mnr)"CAAX"
    *** cells: HEK293 in BMS
    *** source: 11889038-Fig-3a
  *** xRala[GST]IP GTP-association[TLC] is unchanged itpo xRasGrp1
    *** cells: HEK293T in BMS
    *** source: 9789079-Fig-2c
  *** xRala[GST]IP GTP-association[TLC] is unchanged itpo xRasGrp2
    *** cells: HEK293T in BMS
    *** source: 9789079-Fig-2a
  *** xRala[tAb] GTP-association[BDPD] is increased itpo xPlce1
    *** cells: COS7 in BMLS
    *** source: 11395506-Fig-4a
  *** xRala[tAb] GTP-association[BDPD] is increased itpo xRap1Gds1
    *** cells: HEK293T in BMLS
    *** source: 10934204-Fig-3b
  *** xRala[tAb] GTP-association[BDPD] is unchanged itpo xCdc42(G12V)"CA"
    *** cells: NIH3T3<xInsR> in BMS
    *** source: 11046144-Fig-5c
  *** xRala[tAb] GTP-association[BDPD] is unchanged itpo xRapGef1
    *** cells: HEK293T in BMLS
    *** source: 10747847-Fig-3b
  *** xRala[tAb] GTP-association[BDPD] is unchanged itpo xRapGef1
    *** cells: HEK293T in BMLS
    *** source: 10934204-Fig-3b
  *** xRala[tAb] GTP-association[BDPD] is unchanged itpo xRapGef2
    *** cells: COS7 in BMS
    *** source: 10608883-Fig-3b
  *** xRala[tAb] GTP-association[BDPD] is unchanged itpo xRapGef2
    *** cells: HEK293T in BMLS
    *** source: 10934204-Fig-3b
  *** xRala[tAb] GTP-association[BDPD] is unchanged itpo xRapGef5
    *** cells: HEK293T in BMLS
    *** source: 10934204-Fig-3b
  *** xRala[tAb] GTP-association[BDPD] is unchanged itpo xRasGrp3
    *** cells: HEK293T in BMLS
    *** source: 10934204-Fig-3b
  *** xRala[tAb] GTP-association[BDPD] is unchanged itpo xSh2d3c
    *** cells: HEK293T in BMS
    *** source: 12432078-Fig-2c
  *** xRala[tAb]IP GTP-association[TLC] is increased itpo xBcar3
    *** cells: HEK293 in BMS
    *** inhibited by: xBcar1 [addition]
    *** source: 10896938-Fig-1a,8
  *** xRala[tAb]IP GTP-association[TLC] is increased itpo xHras(G12V)"CA"
    *** cells: COS7 in BMLS
    *** enhanced by: xRalGds [addition]
    *** source: 11748241-Fig-1
  *** xRala[tAb]IP GTP-association[TLC] is increased itpo xHras(G12V)"CA"
    *** cells: COS7 in BMLS
    *** source: 11748241-Fig-3b
  *** xRala[tAb]IP GTP-association[TLC] is increased itpo xHras(G12V)"CA"
    *** cells: COS7<xRalGds> in BMLS
    *** source: 11748241-Fig-3a
  *** xRala[tAb]IP GTP-association[TLC] is unchanged itpo xBcar1
    *** cells: HEK293 in BMS
    *** source: 10896938-Fig-8
  *** xRala[tAb]IP GTP-association[TLC] is unchanged itpo xRasGrp3
    *** cells: HEK293T in BMS
    *** source: 10835426-Fig-3a
  *** rRalb GDP-dissociation[Mant-GDP] is unchanged by rRasGef1a
    *** cells: none
    *** source: 19645719-Fig-1c
  *** rRalb GDP-dissociation[Mant-GDP] is unchanged by rRasGef1b
    *** cells: none
    *** source: 19645719-Fig-1c
*** Ralb--
  *** xRalb[Ab] GTP-association[BDPD] is unchanged itpo xHras(G12V)"CA"
    *** cells: COS7 in BMS
    *** source: 9663394-Fig-1b
  *** rRalb{NucFree}[GST] boundby[WB] rRgl2(1-518)"delRBD"[tAb] is detectable
    *** cells: none
    *** inhibited by: rRalb{GTPgS} [substitution]
    *** inhibited by: rRalb{GDP} [substitution]
    *** source: 10869344-Fig-6b
  *** rRalb{NucFree}[GST] boundby[WB] rRgl3(1-557)"delRBD"[tAb] is detectable
    *** cells: none
    *** inhibited by: rRalb{GTPgS} [substitution]
    *** inhibited by: rRalb{GDP} [substitution]
    *** source: 10869344-Fig-6b
  *** rRalb{NucFree}[GST] boundby[WB] rRgl3(1-557)"delRBD"[tAb] is detectable
    *** cells: none
    *** source: 10869344-Fig-6a
  *** xRalbp1[tAb] copptby[WB] xReps2[tAb] is detectable
    *** cells: CHO<xInsR><xReps2><xRalbp1> in BMS
    *** unaffected by: xReps2(P423A/P426A) [substitution]
    *** source: 12149250-Fig-4c
*** RalGds--
  *** RalGds[Ab] copptby[WB] Pdpk1[Ab] is detectable
    *** cells: HEK293 in BMLS
    *** source: 11889038-Fig-6a
  *** RalGds[Ab] snaggedby[WB] rRhoa(G14V){GTP}[GST] is undetectable
    *** cells: rThyrocytes in BMLS
    *** source: 9038168-Fig-4
  *** xRalGds[tAb] copptby[WB] Jip1[Ab] is detectable
    *** cells: COS7 in BMS
    *** source: 18285454-Fig-6e
  *** xRalGds[tAb] copptby[WB] Pdpk1[Ab] is detectable
    *** cells: HEK293 in BMLS
    *** source: 11889038-Fig-6b
  *** xRalGds[tAb] copptby[WB] xAkt1[tAb] is detectable
    *** cells: COS7 in BMS
    *** partially reqs: Jip1 [RNAi] no-bkg-control
    *** source: 18285454-Fig-7c
  *** xRalGds[tAb] copptby[WB] xJip1[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 18285454-Fig-6b
  *** xRalGds[tAb] copptby[WB] xPdpk1[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 11889038-Fig-6c,6d
  *** xRalGps1[tAb] snaggedby[WB] rGrb2[GST] is detectable
    *** cells: HEK293T in BMS
    *** source: 10747847-Fig-4b
*** RalGps1a--
  *** xRalGps1a[tAb] snaggedby[WB] rHras{NucFree}[GST] is undetectable
    *** cells: HEK293T in BMS
    *** source: 10747847-Fig-3a
  *** xRalGps1a[tAb] snaggedby[WB] rRap1a{NucFree}[GST] is undetectable
    *** cells: HEK293T in BMS
    *** source: 10747847-Fig-3a
  *** xRalGps1a[tAb] snaggedby[WB] rRap2b{NucFree}[GST] is undetectable
    *** cells: HEK293T in BMS
    *** source: 10747847-Fig-3a
  *** xRalGps1a[tAb] snaggedby[WB] rRheb{NucFree}[GST] is undetectable
    *** cells: HEK293T in BMS
    *** source: 10747847-Fig-3a
  *** xRalGps1a[tAb] snaggedby[WB] rRras2{NucFree}[GST] is undetectable
    *** cells: HEK293T in BMS
    *** source: 10747847-Fig-3a
  *** xRalGps1b[tAb] snaggedby[WB] rRap1a{NucFree}[GST] is undetectable
    *** cells: HEK293T in BMS
    *** source: 10747847-Fig-3a
  *** xRalGps1b[tAb] snaggedby[WB] rRap2b{NucFree}[GST] is undetectable
    *** cells: HEK293T in BMS
    *** source: 10747847-Fig-3a
  *** xRalGps1b[tAb] snaggedby[WB] rRras{NucFree}[GST] is undetectable
    *** cells: HEK293T in BMS
    *** source: 10747847-Fig-3a
  *** rRan GTP-hydrolysis[32P-GTP] is unchanged by rSipa1
    *** cells: none
    *** source: 9346962-Fig-3a
*** Ran--
  *** rRan{GDP} GTP-association[35S-GTPgS] is unchanged by rVav1{Yphos}
    *** cells: none
    *** comment: rVav1 was phosphorylated by rLck
    *** unaffected by: rVav1 [substitution]
    *** source: 8990121-Fig-2a
*** Ranbp2--
  *** Ranbp2[Ab] copptby[WB] Smad2[Ab] is detectable
    *** cells: COS1 in BMS
    *** source: 12191473-Fig-1e
  *** rRanbp9[35S] boundby[WB] rSos1[Ab] is detectable
    *** cells: none
    *** source: 12147692-Fig-5d
  *** xRanbp9[tAb] copptby[WB] Sos1[Ab] is detectable
    *** cells: HEK293<xRanbp9> in BMLS
    *** source: 12147692-Fig-5c
  *** xRankR[tAb] copptby[WB] Cbl[Ab] is increased itpo xSrc
    *** cells: HEK293T<xRankR> in BMS
    *** source: 11406619-Fig-2a
  *** xRankR[tAb] copptby[WB] xCbl[Ab] is detectable
    *** cells: HEK293T<xRankR><xCbl><xSrc> in BMS
    *** inhibited by: xSrc(K295M) [substitution]
    *** source: 11406619-Fig-2b
  *** xRankR[tAb] copptby[WB] xCbl[Ab] is increased itpo xSrc
    *** cells: HEK293T<xRankR><xCbl> in BMS
    *** source: 11406619-Fig-2a
  *** xRankR[tAb] copptby[WB] xCblb[Ab] is detectable
    *** cells: HEK293T<xRankR><xCblb><xSrc> in BMS "treated with MG132 for 4 hr"
    *** inhibited by: xSrc(K295M) [substitution]
    *** source: 11406619-Fig-2c
  *** xRankR[tAb] prot-exp[WB] is decreased itpo xSrc
    *** cells: HEK293T<xRankR><xCblb> in BMS
    *** reversed by: xCblb(mnr)"del-nterm-SH2" [substitution]
    *** source: 11406619-Fig-2d
  *** xRankR[tAb]IP Yphos[pYAb] is increased itpo xSrc
    *** cells: HEK293T<xRankR> in BMS
    *** inhibited by: xSrc(K295M) [substitution]
    *** source: 11406619-Fig-3b
  *** xRankR[tAb]IP Yphos[pYAb] is increased itpo xSrc
    *** cells: HEK293T<xRankR> in BMS
    *** unaffected by: xRankR(Y345F) [substitution]
    *** unaffected by: xRankR(Y440F) [substitution]
    *** inhibited by: xRankR(Y468F) [substitution]
    *** source: 11406619-Fig-3b
  *** xRap1?[tAb] GTP-association[BDPD] is decreased itpo xRapGef1(mnr)"CBR"
    *** cells: HEK293T<xRap1?> in BMS
    *** source: 10753869-Fig-4c
  *** xRap1?[tAb] GTP-association[BDPD] is increased itpo xGab1
    *** cells: HEK293T<xRap1?> in BMS
    *** inhibited by: xGab1(del(242-410)) [substitution]
    *** source: 10753869-Fig-5
  *** rRap1a GDP-dissociation[3H-GDP] is unchanged by rRalGds
    *** cells: none
    *** source: 8094051-Fig-5
  *** rRap1a GDP-dissociation[3H-GDP] is unchanged by rRasGrf1
    *** cells: none
    *** source: 8524240-Fig-2b
  *** rRap1a GDP-dissociation[Mant-GDP] is unchanged by rRasGef1a
    *** cells: none
    *** source: 19645719-Fig-1c
  *** rRap1a GDP-dissociation[Mant-GDP] is unchanged by rRasGef1b
    *** cells: none
    *** source: 19645719-Fig-1c
  *** rRap1a GTP-hydrolysis[32P-GTP] is unchanged by rNf1
    *** cells: none
    *** source: 10777492-Fig-3
  *** rRap1a GTP-hydrolysis[32P-GTP] is unchanged by rRasa1
    *** cells: none
    *** source: 10777492-Fig-3
  *** rRap1a GTP-hydrolysis[32P-GTP] is unchanged by rRasa2
    *** cells: none
    *** source: 10777492-Fig-3
  *** rRap1a GTP-hydrolysis[32P-GTP] is unchanged by rRasa3
    *** cells: none
    *** source: 10777492-Fig-3
*** Rap1a--
  *** xRap1a(G12V)"CA"[tAb] copptby[WB] xMkk4[tAb] is undetectable
    *** cells: COS1 in BMS
    *** source: 9808624-Fig-3d
  *** xRap1a[Ab] GTP-association[BDPD] is increased itpo xDock4
    *** cells: HEK293T in BMS
    *** inhibited by: xDock4(P1718L)"Crk-BS-mut" [substitution]
    *** source: 12628187-Fig-4c
  *** Rap1a[Ab] infraction(nuclear)[WB] is detectable
    *** cells: HL60 in BMS
    *** source: 9346962-Fig-4
  *** Rap1a[Ab] infraction(P100)[WB] is detectable
    *** cells: HL60 in BMS
    *** source: 9346962-Fig-4
  *** Rap1a[Ab] infraction(S100)[WB] is undetectable
    *** cells: HL60 in BMS
    *** source: 9346962-Fig-4
  *** xRap1a[GST]IP GTP-association[TLC] is increased itpo xRapGef4
    *** cells: HEK293T in BMS
    *** source: 9856955-Fig-2a
  *** xRap1a[GST]IP GTP-association[TLC] is unchanged itpo xRapGef3
    *** cells: HEK293T in BMS
    *** source: 9856955-Fig-2a
  *** xRap1a[GST]IP GTP-association[TLC] is unchanged itpo xRasGrp1
    *** cells: HEK293T in BMS
    *** source: 9789079-Fig-2c
  *** xRap1a[GST]IP GTP-association[TLC] is unchanged itpo xSos1
    *** cells: COS7 in BMS
    *** source: 8524240-Fig-4
  *** xRap1a[tAb] GTP-association[BDPD] is decreased itpo xRap1Gap
    *** cells: CHO<xAdoRa2a> in BMLS "containing adenosine deaminase"
    *** source: 12082090-Fig-2a
  *** xRap1a[tAb] GTP-association[BDPD] is increased itpo xBcar1
    *** cells: HEK293T in BMS
    *** enhanced by: xSh2d3c [addition]
    *** source: 12432078-Fig-3a
  *** xRap1a[tAb] GTP-association[BDPD] is increased itpo xCrk
    *** cells: HEK293T in BMS
    *** source: 12432078-Fig-3b
  *** xRap1a[tAb] GTP-association[BDPD] is increased itpo xRap1Gds1
    *** cells: HEK293T in BMLS
    *** source: 10934204-Fig-3b
  *** xRap1a[tAb] GTP-association[BDPD] is increased itpo xRapGef5
    *** cells: HEK293T in BMLS
    *** source: 10934204-Fig-3b
  *** xRap1a[tAb] GTP-association[BDPD] is increased itpo xRapGef5
    *** cells: HEK293T in BMS
    *** partially inhibited by: xMras(Q71L)"CA" [addition]
    *** source: 10934204-Fig-7a,7b
  *** xRap1a[tAb] GTP-association[BDPD] is increased itpo xRasGrp3
    *** cells: HEK293T in BMLS
    *** source: 10934204-Fig-3b
  *** xRap1a[tAb] GTP-association[BDPD] is increased itpo xRasGrp3
    *** cells: RAT1 in BMLS
    *** source: 11880369-Fig-2c
  *** xRap1a[tAb] GTP-association[BDPD] is increased itpo xSh2d3c
    *** cells: HEK293T in BMS
    *** enhanced by: xBcar1 [addition]
    *** source: 12432078-Fig-1,3a,3b
  *** xRap1a[tAb] GTP-association[BDPD] is increased itpo xSh2d3c(myr)"CA"
    *** cells: HEK293T in BMS
    *** inhibited by: xBcar1(mnr)"substrate-domain-mut" [addition]
    *** inhibited by: xCrk(W169L)"DN" [addition]
    *** inhibited by: xRapGef1(del(CatDom))"DN" [addition]
    *** source: 12432078-Fig-5
  *** xRap1a[tAb] GTP-association[BDPD] is unchanged itpo xMras(Q71L)"CA"
    *** cells: HEK293T in BMS
    *** source: 10934204-Fig-7a
  *** xRap1a[tAb] GTP-association[BDPD] is unchanged itpo xRalGps1
    *** cells: COS7 in BMS
    *** source: 10889189-Fig-4b
  *** xRap1a[tAb] GTP-association[BDPD] is unchanged itpo xRalGps1
    *** cells: HEK293T in BMLS
    *** source: 10747847-Fig-3b
  *** xRap1a[tAb] GTP-association[BDPD] is unchanged itpo xRasGrp4
    *** cells: RAT1 in BMLS
    *** source: 11880369-Fig-2c
  *** xRap1a[tAb] GTP-association[BDPD] is unchanged itpo xRgl2
    *** cells: HEK293T in BMLS
    *** source: 10747847-Fig-3b
  *** xRap1a[tAb] GTP-association[BDPD] is unchanged itpo xRgl2
    *** cells: HEK293T in BMLS
    *** source: 10934204-Fig-3b
  *** xRap1a[tAb] GTP-association[BDPD] is unchanged itpo xRgl2
    *** cells: RAT1 in BMLS
    *** source: 11880369-Fig-2c
  *** xRap1a[tAb]IP GTP-association[TLC] is decreased itpo xRap1Gap
    *** cells: HEK293T<xRap1a> in BMLS
    *** source: 12842888-Fig-1
  *** xRap1a[tAb]IP GTP-association[TLC] is increased itpo xBcar3
    *** cells: HEK293 in BMS
    *** source: 10896938-Fig-1c
  *** xRap1a[tAb]IP GTP-association[TLC] is increased itpo xRapGef5
    *** cells: HEK293T in BMS
    *** source: 10913189-Fig-2a
  *** xRap1a[tAb]IP GTP-association[TLC] is increased itpo xRasGrp3
    *** cells: HEK293T in BMS
    *** source: 10835426-Fig-3a
  *** xRap1a[tAb]IP GTP-association[TLC] is unchanged itpo xCrkL
    *** cells: PC12 in BMLS
    *** source: 9560161-Fig-4d
  *** xRap1a[tAb]IP GTP-association[TLC] is unchanged itpo xRasGrp1
    *** cells: HEK293T in BMS
    *** source: 10835426-Fig-3a
  *** xRap1a[tAb]IP GTP-association[TLC] is unchanged itpo xTsc1
    *** cells: HEK293T<xRap1a> in BMLS
    *** unaffected by: xTsc2 [addition]
    *** source: 12842888-Fig-1
  *** xRap1a[tAb]IP GTP-association[TLC] is unchanged itpo xTsc2
    *** cells: HEK293T<xRap1a> in BMLS
    *** unaffected by: xTsc1 [addition]
    *** source: 12842888-Fig-1
  *** rRap1a{GTPgS}[Ab] boundby[WB] rPlce1(2094-2033)[MalBP] is detectable
    *** cells: none
    *** inhibited by: rRap1a{GDP} [substitution]
    *** source: 11022048-Fig-2a
  *** rRap1b GDP-dissociation[Mant-GDP] is unchanged by rRasGef1a
    *** cells: none
    *** source: 19645719-Fig-1c
  *** rRap1b GDP-dissociation[Mant-GDP] is unchanged by rRasGef1a
    *** cells: none
    *** unaffected by: rRap1b(F39A) [substitution]
    *** source: 19645719-Fig-3c
  *** rRap1b GDP-dissociation[Mant-GDP] is unchanged by rRasGef1b
    *** cells: none
    *** source: 19645719-Fig-1c
  *** rRap1b GDP-dissociation[Mant-GDP] is unchanged by rRasGef1b
    *** cells: none
    *** source: 19645719-Fig-3d
*** Rap1b--
  *** xRap1b[tAb] GTP-association[BDPD] is increased itpo xRapGef1
    *** cells: COS7 in BMS
    *** source: 10608883-Fig-3b
  *** xRap1b[tAb] GTP-association[BDPD] is increased itpo xRapGef2
    *** cells: COS7 in BMS
    *** source: 10608883-Fig-3b
*** Rap1Gds1--
  *** rRap1Gds1[Ab] boundby[WB] rHras{NucFree}[GST] is detectable
    *** cells: none
    *** inhibited by: rHras{GTPgS} [substitution]
    *** inhibited by: rHras{GDP} [substitution]
    *** source: 11948427-Fig-2a
  *** rRap1Gds1[Ab] boundby[WB] rNras{NucFree}[GST] is detectable
    *** cells: none
    *** inhibited by: rNras{GTPgS} [substitution]
    *** inhibited by: rNras{GDP} [substitution]
    *** source: 11948427-Fig-2a
  *** Rap1Gds1[Ab] snaggedby[WB] rHras(S17N)[GST] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: rHras(G12V) [substitution]
    *** inhibited by: rHras(S17N/E37G) [substitution]
    *** source: 11948427-Fig-1c
  *** Rap1Gds1[MS] copptby[WB] xMras(H81L)"CA"[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 16630891-Fig-1a
*** Rap1s--
  *** Rap1s[Ab] GTP-association[BDPD] is decreased itao Arms [RNAi]
    *** cells: PC12 in BMLS
    *** source: 15167895-Fig-7a
  *** Rap1s[Ab] GTP-association[BDPD] is detectable
    *** cells: NIH3T3 in BMS
    *** inhibited by: xJak2(K882E)"KD" [addition]
    *** source: 12734187-Fig-3a
  *** Rap1s[Ab] GTP-association[BDPD] is detectable
    *** cells: NIH3T3 in BMS
    *** inhibited by: xSrc(K295R/Y527F)"KD" [addition]
    *** source: 12734187-Fig-3a
  *** Rap1s[Ab] GTP-association[BDPD] is increased itpo xRasGrp3
    *** cells: RAT1A in BMS
    *** source: 10835426-Fig-7d
  *** Rap1s[Ab] GTP-association[BDPD] is unchanged itpo xRasGrp1
    *** cells: RAT1A in BMS
    *** source: 10835426-Fig-7d
*** Rap2?--
  *** xRap2?[tAb]IP GTP-association[TLC] is decreased itpo xRap1Gap
    *** cells: COS7 in BMS
    *** source: 12820960-Fig-1d
  *** xRap2?[tAb]IP GTP-association[TLC] is unchanged itpo (xTsc1 + xTsc2)
    *** cells: COS7 in BMS
    *** source: 12820960-Fig-1d
  *** rRap2a GDP-dissociation[3H-GDP] is increased by rPlce1
    *** cells: none
    *** source: 11395506-Fig-3
  *** rRap2a GDP-dissociation[3H-GDP] is unchanged by rRalGds
    *** cells: none
    *** source: 8094051-Fig-5
  *** rRap2a GDP-dissociation[Mant-GDP] is unchanged by rRapGef1
    *** cells: none
    *** source: 10913189-Fig-2b
  *** rRap2a GDP-dissociation[Mant-GDP] is unchanged by rRasGrp2
    *** cells: none
    *** source: 10913189-Fig-2b
*** Rap2a--
  *** xRap2a[Ab] copptby[WB] xSh2d3c[Ab] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: xSh2d3c(Y635E) [substitution]
    *** unaffected by: xSh2d3c(Y635F) [substitution]
    *** source: 15272013-Fig-4b
  *** Rap2a[Ab] infraction(nuclear)[WB] is detectable
    *** cells: HL60 in BMS
    *** source: 9346962-Fig-4
  *** Rap2a[Ab] infraction(P100)[WB] is detectable
    *** cells: HL60 in BMS
    *** source: 9346962-Fig-4
  *** Rap2a[Ab] infraction(S100)[WB] is undetectable
    *** cells: HL60 in BMS
    *** source: 9346962-Fig-4
  *** xRap2a[tAb] GTP-association[BDPD] is unchanged itpo xRapGef1
    *** cells: HEK293T in BMS
    *** source: 10913189-Fig-1b
  *** xRap2a[tAb] GTP-association[BDPD] is unchanged itpo xRasGrp2
    *** cells: HEK293T in BMS
    *** source: 10913189-Fig-1b
  *** xRap2a[tAb]IP GTP-association[TLC] is decreased itpo xRap1Gap2
    *** cells: HEK293T in BMS
    *** source: 10913189-Fig-4a,4b
  *** xRap2a[tAb]IP GTP-association[TLC] is increased itpo xRapGef1
    *** cells: HEK293T in BMS
    *** source: 10913189-Fig-2a
  *** xRap2a[tAb]IP GTP-association[TLC] is increased itpo xRapGef5
    *** cells: HEK293T in BMS
    *** source: 10913189-Fig-2a
  *** xRap2a[tAb]IP GTP-association[TLC] is increased itpo xRasGrp2
    *** cells: HEK293T in BMS
    *** source: 10835426-Fig-3a
  *** xRap2a[tAb]IP GTP-association[TLC] is increased itpo xRasGrp2
    *** cells: HEK293T in BMS
    *** source: 10913189-Fig-2a
  *** xRap2a[tAb]IP GTP-association[TLC] is increased itpo xRasGrp3
    *** cells: HEK293T in BMS
    *** source: 10835426-Fig-3a
  *** xRap2a[tAb]IP GTP-association[TLC] is unchanged itpo xRapGef1
    *** cells: HEK293T in BMS
    *** source: 10835426-Fig-3a
  *** xRap2a[tAb]IP GTP-association[TLC] is unchanged itpo xRasGrp1
    *** cells: HEK293T in BMS
    *** source: 10835426-Fig-3a
*** Rap2b--
  *** rRap2b{NucFree}[GST] boundby[WB] rRgl3(1-557)"delRBD"[tAb] is undetectable
    *** cells: none
    *** source: 10869344-Fig-6a
*** Rap2s--
  *** Rap2s[Ab] GTP-association[BDPD] is detectable
    *** cells: mEFs in BMLS
    *** does not req: Tsc2 [KO]
    *** source: 12820960-Fig-1a
  *** Rap2s[Ab] GTP-association[BDPD] is detectable
    *** cells: NIH3T3 in BMS
    *** inhibited by: xJak2(K882E)"KD" [addition]
    *** source: 12734187-Fig-3a
  *** Rap2s[Ab] GTP-association[BDPD] is detectable
    *** cells: NIH3T3 in BMS
    *** inhibited by: xSrc(K295R/Y527F)"KD" [addition]
    *** source: 12734187-Fig-3a
  *** Rap2s[Ab] GTP-association[BDPD] is detectable
    *** cells: NIH3T3 in BMS
    *** unaffected by: xRapGef1 [addition]
    *** inhibited by: xRapGef1(Y504F) [substitution]
    *** source: 12734187-Fig-5g
  *** Rap80[Ab] locatedin(subnuclear-bodies)[IHC] is detectable
    *** cells: HELA in BMS "treated with IR for 6 hr"
    *** reqs: Rnf8 [RNAi]
    *** source: 18001825-Fig-5b
  *** Rap80[Ab] locatedin(subnuclear-bodies)[IHC] is detectable
    *** cells: HELA in BMS "treated with IR for 6 hr"
    *** reqs: Ubc13 [RNAi]
    *** source: 18001825-Fig-5b
  *** Rap80[Ab] locatedin(subnuclear-bodies)[IHC] is detectable
    *** cells: HELA<Rnf8~kd><xRnf8> in BMS "treated with IR for 6 hr"
    *** inhibited by: xRnf8(mnr)"delFHA" [substitution]
    *** inhibited by: xRnf8(mnr)"delRING" [substitution]
    *** source: 18001825-Fig-5d
*** RapGef1
  *** RapGef1[Ab] copptby[WB] Crk[Ab] is undetectable
    *** cells: 32D<xEpoR> in BMLS "IL3 deprived"
    *** unaffected by: Epo (1 min) [stim]
    *** unaffected by: IL3 (1 min) [stim]
    *** source: 9344843-Fig-3
  *** RapGef1[Ab] copptby[WB] CrkL[Ab] is detectable
    *** cells: 32D<xEpoR> in BMLS "IL3 deprived"
    *** unaffected by: Epo (1 min) [stim]
    *** unaffected by: IL3 (1 min) [stim]
    *** source: 9344843-Fig-3
  *** RapGef1[Ab] copptby[WB] CrkL[Ab] is detectable
    *** cells: DAUDI in BMS
    *** unaffected by: Ifna2 (5,20 min) [stim]
    *** source: 9374471-Fig-6
  *** RapGef1[Ab] copptby[WB] CrkL[Ab] is detectable
    *** cells: U266 in BMLS
    *** unaffected by: Ifna2 (5 min) [stim]
    *** source: 9374471-Fig-6
  *** RapGef1[Ab] copptby[WB] Grb2[Ab] is undetectable
    *** cells: 32D<xEpoR> in BMLS "IL3 deprived"
    *** unaffected by: Epo (1 min) [stim]
    *** unaffected by: IL3 (1 min) [stim]
    *** source: 9344843-Fig-3
  *** RapGef1[Ab] copptby[WB] Shc1[Ab] is undetectable
    *** cells: 32D<xEpoR> in BMLS "IL3 deprived"
    *** source: 9344843-Fig-3
  *** RapGef1[Ab] copptby[WB] Shp2[Ab] is undetectable
    *** cells: 32D<xEpoR> in BMLS "IL3 deprived"
    *** unaffected by: Epo (1 min) [stim]
    *** unaffected by: IL3 (1 min) [stim]
    *** source: 9344843-Fig-3
  *** RapGef1[Ab] copptby[WB] xCrkL[tAb] is detectable
    *** cells: HEK293<xTrka><xCrkL> in BMS
    *** unaffected by: xArms [addition]
    *** source: 15167895-Fig-5d
  *** RapGef1[Ab] snaggedby[WB] rCrkL[GST] is detectable
    *** cells: U266 in BMLS
    *** source: 9374471-Fig-6
  *** RapGef1[Ab]IP Yphos[pYAb] is detectable
    *** cells: PC12 in BMLS
    *** source: 11466412-Fig-3a
  *** RapGef1[Ab]IP Yphos[pYAb] is detectable
    *** cells: PC12 in BMLS
    *** source: 11466412-Fig-3b
  *** xRapGef1[GST]IP Yphos[pYAb] is increased itpo xSrc(mnr)"vSrc"
    *** cells: 3Y1 in BMS
    *** comment: lysates were denatured before IP to remove coppt proteins
    *** source: 10318861-Fig-3b
  *** xRapGef1[GST]IP Yphos[pYAb] is increased itpo xSrc(mnr)"vSrc"
    *** cells: 3Y1 in BMS
    *** source: 10318861-Fig-3a
  *** xRapGef1[GST]IP Yphos[pYAb] is unchanged itpo xHras(mnr)"vHa-Ras"
    *** cells: 3Y1 in BMS
    *** comment: lysates were denatured before IP to remove coppt proteins
    *** source: 10318861-Fig-3b
  *** xRapGef1[GST]IP Yphos[pYAb] is unchanged itpo xHras(mnr)"vHa-Ras"
    *** cells: 3Y1 in BMS
    *** source: 10318861-Fig-3a
  *** xRapGef1[phosAb] phos(Y504)[phosAb] is increased itpo xHck
    *** cells: COS1 in BMS
    *** inhibited by: xRapGef1(Y504F) [substitution]
    *** source: 15320955-Fig-2a
  *** RapGef1[phosAb] phos(Y504)[phosAb] is increased itpo xHck
    *** cells: COS1 in BMS
    *** inhibited by: xRapGef1(Y504F) [substitution]
    *** source: 15320955-Fig-4a
  *** xRapGef1[phosAb] phos(Y504)[phosAb] is increased itpo xSrc
    *** cells: COS1 in BMS
    *** inhibited by: xRapGef1(Y504F) [substitution]
    *** source: 15320955-Fig-2b
  *** RapGef1[phosAb] phos(Y504)[phosAb] is increased itpo xSrc
    *** cells: COS1 in BMS
    *** inhibited by: xRapGef1(Y504F) [substitution]
    *** source: 15320955-Fig-4a
*** RapGef2--
  *** rRapGef2[tAb] boundby[WB] rHras{NucFree}[GST] is undetectable
    *** cells: none
    *** source: 10934204-Fig-3a
  *** rRapGef2[tAb] boundby[WB] rRala{NucFree}[GST] is undetectable
    *** cells: none
    *** source: 10934204-Fig-3a
  *** rRapGef2[tAb] boundby[WB] rRap2b{NucFree}[GST] is detectable
    *** cells: none
    *** source: 10934204-Fig-3a
  *** rRapGef2[tAb] boundby[WB] rRheb{NucFree}[GST] is undetectable
    *** cells: none
    *** source: 10934204-Fig-3a
  *** rRapGef2[tAb] boundby[WB] rRras{NucFree}[GST] is undetectable
    *** cells: none
    *** source: 10934204-Fig-3a
  *** rRapGef2[tAb] boundby[WB] rRras2{NucFree}[GST] is undetectable
    *** cells: none
    *** source: 10934204-Fig-3a
  *** xRapGef2[tAb] copptby[WB] xKras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRapGef2[tAb] copptby[WB] xMras(Q71L)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRapGef2[tAb] copptby[WB] xNras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRapGef2[tAb] copptby[WB] xRras(G38V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRapGef2[tAb] copptby[WB] xRras2(G23V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRapGef2[tAb] snaggedby[WB] rHras{GTPgS}[GST] is undetectable
    *** cells: HEK293T in BMS
    *** source: 10934204-Fig-5a
  *** xRapGef2[tAb] snaggedby[WB] rMras{GTPgS}[GST] is undetectable
    *** cells: HEK293T in BMS
    *** source: 10934204-Fig-5a
  *** xRapGef2[tAb] snaggedby[WB] rRala{GTPgS}[GST] is undetectable
    *** cells: HEK293T in BMS
    *** source: 10934204-Fig-5a
  *** xRapGef2[tAb] snaggedby[WB] rRras{GTPgS}[GST] is undetectable
    *** cells: HEK293T in BMS
    *** source: 10934204-Fig-5a
  *** xRapGef2[tAb] snaggedby[WB] rRras2{GTPgS}[GST] is undetectable
    *** cells: HEK293T in BMS
    *** source: 10934204-Fig-5a
*** RapGef5--
  *** rRapGef5[tAb] boundby[WB] rHras{NucFree}[GST] is undetectable
    *** cells: none
    *** source: 10934204-Fig-3a
  *** rRapGef5[tAb] boundby[WB] rRala{NucFree}[GST] is undetectable
    *** cells: none
    *** source: 10934204-Fig-3a
  *** rRapGef5[tAb] boundby[WB] rRap1a{NucFree}[GST] is detectable
    *** cells: none
    *** source: 10934204-Fig-3a
  *** rRapGef5[tAb] boundby[WB] rRap2b{NucFree}[GST] is undetectable
    *** cells: none
    *** source: 10934204-Fig-3a
  *** rRapGef5[tAb] boundby[WB] rRheb{NucFree}[GST] is undetectable
    *** cells: none
    *** source: 10934204-Fig-3a
  *** rRapGef5[tAb] boundby[WB] rRras{NucFree}[GST] is undetectable
    *** cells: none
    *** source: 10934204-Fig-3a
  *** rRapGef5[tAb] boundby[WB] rRras2{NucFree}[GST] is undetectable
    *** cells: none
    *** source: 10934204-Fig-3a
  *** xRapGef5[tAb] copptby[WB] xHras(Q71L)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 10934204-Fig-6a
  *** xRapGef5[tAb] copptby[WB] xMras(Q71L)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 10934204-Fig-6a
  *** xRapGef5[tAb] copptby[WB] xMras[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 10934204-Fig-6a
  *** xRapGef5[tAb] copptby[WB] xRras(Q71L)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 10934204-Fig-6a
  *** xRapGef5[tAb] snaggedby[WB] rHras{GTPgS}[GST] is undetectable
    *** cells: HEK293T in BMS
    *** source: 10934204-Fig-5a
  *** xRapGef5[tAb] snaggedby[WB] rMras{GDP}[GST] is undetectable
    *** cells: HEK293T in BMS
    *** source: 10934204-Fig-5b
  *** xRapGef5[tAb] snaggedby[WB] rMras{GTPgS}[GST] is detectable
    *** cells: HEK293T in BMS
    *** source: 10934204-Fig-5a
  *** xRapGef5[tAb] snaggedby[WB] rMras{GTPgS}[GST] is detectable
    *** cells: HEK293T in BMS
    *** source: 10934204-Fig-5b
  *** xRapGef5[tAb] snaggedby[WB] rRala{GTPgS}[GST] is undetectable
    *** cells: HEK293T in BMS
    *** source: 10934204-Fig-5a
  *** xRapGef5[tAb] snaggedby[WB] rRap1a{GTPgS}[GST] is undetectable
    *** cells: HEK293T in BMS
    *** source: 10934204-Fig-5a
  *** xRapGef5[tAb] snaggedby[WB] rRap2b{GTPgS}[GST] is undetectable
    *** cells: HEK293T in BMS
    *** source: 10934204-Fig-5a
  *** xRapGef5[tAb] snaggedby[WB] rRras{GTPgS}[GST] is undetectable
    *** cells: HEK293T in BMS
    *** source: 10934204-Fig-5a
  *** xRapGef5[tAb] snaggedby[WB] rRras2{GTPgS}[GST] is undetectable
    *** cells: HEK293T in BMS
    *** source: 10934204-Fig-5a
*** Raph1--
  *** xRaph1[tAb] copptby[WB] xHras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xHras(G12V/D38A) [substitution]
    *** inhibited by: xHras(G12V/T35S) [substitution]
    *** inhibited by: xHras(G12V/E37G) [substitution]
    *** inhibited by: xHras(G12V/Y40C) [substitution]
    *** inhibited by: xHras(G12V/D38E) [substitution]
    *** source: 15143186-Fig-6
  *** xRaph1[tAb] copptby[WB] xKras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRaph1[tAb] copptby[WB] xMras(Q71L)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRaph1[tAb] copptby[WB] xNras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRaph1[tAb] copptby[WB] xRap1a(G12V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRaph1[tAb] copptby[WB] xRap2a(G12V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRaph1[tAb] copptby[WB] xRras(G38V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRaph1[tAb] copptby[WB] xRras2(G23V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
*** Raptor--
  *** Raptor[Ab] copptby[WB] (xRagB(Q99L)"GTP"[tAb] + xRagC(Q120L)"GTP"[tAb]) is detectable
    *** cells: HEK293T<xRagB(Q99L)><xRagC(Q120L)> in BMS
    *** unaffected by: xRagC(S75L)"GDP" [substitution]
    *** inhibited by: xRagB(T54L)"GDP" [substitution]
    *** source: 18497260-Fig-1c
  *** Raptor[Ab] copptby[WB] Atm[Ab] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15268862-Fig-1c
  *** Raptor[Ab] copptby[WB] EgfR[Ab] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15268862-Fig-1c
  *** Raptor[Ab] copptby[WB] Mtor[Ab] is detectable
    *** cells: HEK293T in BMS
    *** comment: unaffected by washing IP in 0.2% Chaps
    *** comment: inhibited by washing IP in 0.2% NP40
    *** comment: inhibited by washing IP in 0.2% TritonX100
    *** source: 17510057-Fig-S1a
  *** Raptor[Ab] copptby[WB] Mtor[Ab] is detectable
    *** cells: HEK293T in BMS
    *** does not req: Rictor [RNAi]
    *** does not req: Mlst8 [RNAi]
    *** source: 17510057-Fig-2a
  *** Raptor[Ab] copptby[WB] Mtor[Ab] is detectable
    *** cells: HEK293T in BMS
    *** source: 17510057-Fig-1b
  *** Raptor[Ab] copptby[WB] Protor1[Ab] is undetectable
    *** cells: HEK293 in BMS
    *** comment: coppt is unaffected by detergent used in lysis
    *** source: 17461779-Fig-3b
  *** Raptor[Ab] copptby[WB] Protor1[Ab] is undetectable
    *** cells: HEK293 in BMS
    *** source: 17461779-Fig-3a
  *** Raptor[Ab] copptby[WB] Rictor[Ab] is undetectable
    *** cells: HEK293 in BMS
    *** source: 17043309-Fig-3c
  *** Raptor[Ab] copptby[WB] Rictor[Ab] is undetectable
    *** cells: HEK293 in BMS
    *** source: 17461779-Fig-3a
  *** Raptor[Ab] copptby[WB] Rictor[Ab] is undetectable
    *** cells: HEK293 in BMS
    *** source: 18925875-Fig-3a
  *** Raptor[Ab] copptby[WB] Rictor[Ab] is undetectable
    *** cells: HEK293E in BMS
    *** comment: unaffected by washing ppt with high salt
    *** source: 19446321-Fig-1d
  *** Raptor[Ab] copptby[WB] Rictor[Ab] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15268862-Fig-2b
  *** Raptor[Ab] copptby[WB] Rictor[Ab] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15467718-Fig-1
  *** Raptor[Ab] copptby[WB] Rictor[Ab] is undetectable
    *** cells: HEK293T in BMS
    *** source: 17277771-Fig-1b
  *** Raptor[Ab] copptby[WB] Rictor[Ab] is undetectable
    *** cells: HELA in BMS
    *** source: 17043309-Fig-S5
  *** Raptor[Ab] copptby[WB] Rictor[Ab] is undetectable
    *** cells: mEFs in BMS
    *** source: 18925875-Fig-3d
  *** Raptor[Ab] copptby[WB] Sin1[Ab] is undetectable
    *** cells: HEK293 in BMS
    *** source: 16962653-Fig-1b
  *** Raptor[Ab] copptby[WB] Sin1[Ab] is undetectable
    *** cells: HEK293 in BMS
    *** source: 17461779-Fig-3a
  *** Raptor[Ab] copptby[WB] Sin1[Ab] is undetectable
    *** cells: HELA in BMS
    *** source: 17043309-Fig-S5
  *** Raptor[Ab] copptby[WB] xPras40[tAb] is decreased itpo xAkt1
    *** cells: HEK293T<xPras40><xYwha?> in BMS
    *** reversed by: xPras40(T246A) [substitution]
    *** source: 17277771-Fig-4a
  *** Raptor[Ab] copptby[WB] xProtor1[tAb] is undetectable
    *** cells: HEK293<xProtor1> in BMS
    *** unaffected by: xProtor1b [substitution]
    *** inhibited by: xProtor1g [substitution]
    *** source: 17461779-Fig-2d
  *** Raptor[Ab] copptby[WB] xProtor2[tAb] is undetectable
    *** cells: HEK293<xProtor1> in BMS
    *** source: 17461779-Fig-2d
  *** Raptor[Ab] copptby[WB] xRictor[tAb] is undetectable
    *** cells: HEK293T<xRictor> in BMS
    *** source: 17510057-Fig-1b
  *** Raptor[Ab] copptby[WB] xSin1[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 16962653-Fig-S1a
  *** Raptor[Ab] snaggedby[WB] rEif4ebp1[GST] is increased itao Pras40 [RNAi]
    *** cells: CHO<xInsR> in BMLS
    *** source: 17510057-Fig-6a
  *** Raptor[Ab]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: HEK293 in BMS
    *** comment: ref shows 32P-Mtor but they don't say how they know what it is
    *** comment: ref shows 32P-Eif4ebp1 but they don't say how they know what it is
    *** comment: inhibited by Rapamycin in kinase reaction
    *** source: 15467718-Fig-2b
  *** Raptor[Ab]IP IVKA(Eif4ebp1)[32P-ATP] is detectable
    *** cells: HEK293 in BMS
    *** comment: cells were lysed without detergent
    *** comment: unaffected by Serum-deprivation and/or AA-deprivation
    *** unaffected by: Rapamycin [addition]
    *** source: 12150926-Fig-2b
  *** Raptor[Ab]IP IVKA(Pras40)(T246)[phosAb] is detectable
    *** cells: mEFs in BMS "Leucine deprived"
    *** reqs: Tsc2 [KO]
    *** source: 17386266-Fig-S1
  *** Raptor[Ab]IP IVKA(S6k1)(T412)[phosAb] is detectable
    *** cells: none
    *** comment: Raptor IP is from HEK293E in BMLS
    *** comment: increased when ppt is washed in high salt concentrations
    *** comment: increase is inhibited by addition of rPras40 to IVKA reaction
    *** comment: inhibition is less if rPras40 is phosed on T246 by Akt1
    *** source: 17386266-Fig-7b
  *** Raptor[Ab]IP IVKA(S6k1)(T412)[phosAb] is increased by rAkt1(T308D)
    *** cells: none
    *** comment: Raptor IP is from HEK293E in BMLS
    *** comment: bkg is increased when ppt is washed in high salt concentrations
    *** source: 17386266-Fig-7a
  *** Raptor[Ab]IP IVKA(S6k1)(T412)[phosAb] is unchanged itpo (xRagB(Q99L)"GTP" + xRagC(S75L)"GDP")
    *** cells: HEK293T in BMLS
    *** unaffected by: xRagB(T54L)"GDP" + xRagD(Q121L)"GTP" [substitution]
    *** unaffected by: xRagB + xRagD [substitution]
    *** source: 18497260-Fig-S7
  *** xRaptor[phosAb] phos(S792)[phosAb] is decreased itpo xLkb1(K81I)"KD"
    *** cells: HEK293<xRaptor><xMtor> in BMS
    *** comment: antibody is actually against a phospho-14-3-3 motif
    *** reversed by: xLkb1(WT) [substitution]
    *** source: 18439900-Fig-2b
  *** xRaptor[phosAb] phos(S792)[phosAb] is detectable
    *** cells: HEK293<xRaptor> in BMS
    *** inhibited by: xRaptor(S792A) [substitution]
    *** source: 18439900-Fig-2d
  *** xRaptor[phosAb] phos(S792)[phosAb] is detectable
    *** cells: HEK293<xRaptor> in BMS
    *** inhibited by: xRaptor(S792A) [substitution]
    *** unaffected by: xRaptor(S722A) [substitution]
    *** source: 18439900-Fig-3a
  *** pRaptor[phosAb] phos(S792)[phosAb] is increased by pAmpk{act}
    *** cells: none
    *** comment: the sources of pRaptor and pAmpk{act} are not reported
    *** source: 18439900-Fig-2d
  *** xRaptor[phosAb] phos(S792)[phosAb] is increased itpo xAmpka1(1-312)"CA"
    *** cells: HEK293<xRaptor><xMtor> in BMS
    *** comment: antibody is actually against a phospho-14-3-3 motif
    *** source: 18439900-Fig-2b
  *** pRaptor[tAb] boundby[WB] (xRagB(Q99L)"GTP"[GST]IP + xRagD(S77L)"GDP"[GST]IP) is detectable
    *** cells: none
    *** IPfrom: HEK293T<xRagB(Q99L)><xRagD(S77L)> in BMS
    *** inhibited by: xRagB[GST]IP + xRagD[GST]IP [substitution]
    *** source: 18497260-Fig-1e
  *** pRaptor[tAb] boundby[WB] xRap2a[GST]IP is undetectable
    *** cells: none
    *** IPfrom: HEK293T<xRap2a> in BMS
    *** source: 18497260-Fig-1e
  *** pRaptor[tAb] boundby[WB] xRheb[GST]IP is undetectable
    *** cells: none
    *** IPfrom: HEK293T<xRheb> in BMS
    *** source: 18497260-Fig-1e
  *** xRaptor[tAb] copptby[WB] (xRagA[tAb] + xRagB[tAb]) is undetectable
    *** cells: HEK293T<xRaptor><xRagA><xRagB> in BMS
    *** source: 18497260-Fig-1a
  *** xRaptor[tAb] copptby[WB] (xRagA[tAb] + xRagC[tAb]) is detectable
    *** cells: HEK293T<xRaptor><xRagA><xRagC> in BMS
    *** source: 18497260-Fig-1a
  *** xRaptor[tAb] copptby[WB] (xRagB[tAb] + xRagC[tAb]) is detectable
    *** cells: HEK293T<xRaptor><xRagB><xRagC> in BMS
    *** source: 18497260-Fig-1a
  *** xRaptor[tAb] copptby[WB] (xRagB[tAb] + xRagD[tAb]) is detectable
    *** cells: HEK293T<xRaptor><xMtor><xRagB><xRagD> in BMS
    *** enhanced by: xRagB(Q99L)"GTP" [substitution]
    *** inhibited by: xRagB(T54L)"GDP" [substitution]
    *** source: 18497260-Fig-1b
  *** xRaptor[tAb] copptby[WB] xEif4ebp1[GST] is detectable
    *** cells: HEK293<xRaptor><xEif4ebp1> in BMS
    *** comment: IP was washed with high salt buffer containing NP40
    *** source: 12150926-Fig-4a
  *** xRaptor[tAb] copptby[WB] xEif4ebp1[GST] is detectable
    *** cells: HEK293<xRaptor><xEif4ebp1> in BMS
    *** comment: IP was washed with high salt buffer without detergent
    *** unaffected by: xMtor [addition]
    *** source: 12150926-Fig-4b
  *** xRaptor[tAb] copptby[WB] xLamtor2[tAb] is detectable
    *** cells: HEK293T<xLamtor2><xLamtor3><xLamtor1><xMtor><xRaptor><xRagB(Q99L)"GTP"><xRagD(S77L)"GDP"> in BMS
    *** reqs: xRagB(Q99L)"GTP" and/or xRagD(S77L)"GDP" [omission]
    *** source: 20381137-Fig-2c
  *** xRaptor[tAb] copptby[WB] xMtor[tAb] is detectable
    *** cells: HEK293T<xMtor><xPras40><xRaptor> in BMS
    *** comment: inhibited by replacement of Tween20 by TritonX in lysis buffer
    *** source: 17510057-Fig-2c
  *** xRaptor[tAb] copptby[WB] xPdpk1[GST] is undetectable
    *** cells: HEK293<xRaptor><xPdpk1> in BMS
    *** comment: IP was washed with high salt buffer containing NP40
    *** source: 12150926-Fig-4a
  *** xRaptor[tAb] copptby[WB] xRagD(S77L)"GDP"[tAb] is detectable
    *** cells: HEK293T<xRaptor><xMtor><xRagB(Q99L)><xRagD(S77L)> in BMS
    *** does not req: xMtor [omission]
    *** source: 18497260-Fig-1d
  *** xRaptor[tAb] copptby[WB] xRagD(S77L)"GDP"[tAb] is detectable
    *** cells: HEK293T<xRaptor><xMtor><xRagB(Q99L)><xRagD(S77L)> in BMS
    *** inhibited by: xRagB(T54L)"GDP" + xRagD(Q121L)"GTP" [substitution]
    *** source: 18497260-Fig-1d
  *** xRaptor[tAb] copptby[WB] xRap2a[tAb] is undetectable
    *** cells: HEK293T<xRaptor><xRap2a> in BMS
    *** source: 18497260-Fig-1a
  *** xRaptor[tAb] copptby[WB] xS6k1[GST] is detectable
    *** cells: HEK293<xRaptor><xS6k1> in BMS
    *** comment: IP was washed with high salt buffer containing NP40
    *** source: 12150926-Fig-4a
  *** xRaptor[tAb] copptby[WB] xS6k1[GST] is detectable
    *** cells: HEK293<xRaptor><xS6k1> in BMS
    *** comment: IP was washed with high salt buffer without detergent
    *** unaffected by: xMtor [addition]
    *** source: 12150926-Fig-4b
  *** xRaptor[tAb] copptby[WB] xSin1[Ab] is undetectable
    *** cells: HEK293<xMtor> in BMS
    *** source: 17043309-Fig-3d
  *** xRaptor[tAb] locatedin(cytoplasm)[IHC] is detectable
    *** cells: C2C12<Raptor~null><xRaptor> in BMS
    *** unaffected by: xRaptor(S722A/S792A) [substitution]
    *** unaffected by: xRaptor(S722D/S792D) [substitution]
    *** source: 18439900-Fig-S6c
  *** xRaptor[tAb] oligomerization[2TagPpt] is detectable
    *** cells: HEK293T<xRaptor> in BMS
    *** comment: unaffected by replacement of Tween20 by TritonX in lysis buffer
    *** source: 17510057-Fig-S1c
  *** xRaptor[tAb] snaggedby[WB] rEif4ebp1[Ab] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: rEif4ebp1(F113A) [substitution]
    *** inhibited by: rEif4ebp1(I15A/P16A) [substitution]
    *** source: 12665511-Fig-7
*** Rasa1--
  *** xRasa1(1-448)[tAb] snaggedby[WB] rSocs3(200-225){phos(Y204/Y221)}[GST] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: rSocs3(200-225) [substitution]
    *** inhibited by: rSocs3(200-225){phos(Y204)} [substitution]
    *** unaffected by: rSocs3(200-225){phos(Y221)} [substitution]
    *** source: 11331873-Fig-2c
  *** Rasa1[Ab] copptby[WB] xDok1[tAb] is detectable
    *** cells: CHO<xInsR> in BMLS
    *** inhibited by: xDok1(Y361F) [substitution]
    *** source: 10202139-Fig-6
  *** Rasa1[Ab] copptby[WB] xDok1[tAb] is increased itpo xAbl1(mnr)"vAbl"
    *** cells: HEK293 in BMS
    *** source: 9008161-Fig-3e
  *** Rasa1[Ab] copptby[WB] xDok2[tAb] is increased itpo xLyn
    *** cells: HEK293T in BMS
    *** inhibited by: xDok2(Y276F/Y304F) [substitution]
    *** source: 10428862-Fig-8b
  *** Rasa1[Ab] copptby[WB] xDok2[tAb] is increased itpo xLyn
    *** cells: HEK293T in BMS
    *** source: 10428862-Fig-3c
  *** Rasa1[Ab] infraction(membrane)[WB] is increased itpo xShp2(R465E)"DN"
    *** cells: A431 in BMLS
    *** unaffected by: xShp2 [substitution]
    *** source: 14560030-Fig-5b
  *** Rasa1[Ab] infraction(membrane)[WB] is increased itpo xShp2(R465E)"DN"
    *** cells: COS1 in BMLS
    *** unaffected by: xShp2 [substitution]
    *** source: 14560030-Fig-5a
  *** Rasa1[Ab] snaggedby[WB] rSocs3(200-225)[GST] is detectable
    *** cells: CTLL2 in BMS
    *** enhanced by: rSocs3(200-225){phos(Y204/Y221)} [substitution]
    *** source: 11331873-Fig-2b
  *** Rasa1[Ab] snaggedby[WB] rSocs3(200-225)[GST] is detectable
    *** cells: HT2 in BMS
    *** enhanced by: rSocs3(200-225){phos(Y204/Y221)} [substitution]
    *** source: 11331873-Fig-2b
  *** xRasa1[tAb] copptby[WB] xSocs3[tAb] is increased itpo xJak1
    *** cells: HEK293T in BMS
    *** source: 11331873-Fig-3a
  *** xRasa1[tAb] copptby[WB] xSocs3[tAb] is increased itpo xJak2
    *** cells: HEK293T in BMS
    *** source: 11331873-Fig-3a
*** Rasa2--
  *** xRasa2[Ab] copptby[WB] xGna12[Ab] is detectable
    *** cells: COS7 in BMS
    *** source: 9796816-Fig-6b
*** Rasa3--
  *** rRasa3[Ab] boundby[WB] rHras{GTPgS}[GST] is detectable
    *** cells: none
    *** unaffected by: rHras{GDP} [substitution]
    *** source: 8530488-Fig-4
  *** rRasa3[Ab] boundby[WB] rRala{GTPgS}[GST] is detectable
    *** cells: none
    *** unaffected by: rRala{GDP} [substitution]
    *** source: 8530488-Fig-4
*** RasGrf1--
  *** xRasGrf1[Ab] copptby[WB] xArhGdia[tAb] is undetectable
    *** cells: COS7 in BMLS
    *** unaffected by: Ionomycin [addition]
    *** source: 11285260-Fig-2c
  *** xRasGrf1[Ab]IP Yphos[pYAb] is detectable 
    *** cells: COS<xTrka><xRasGrf1> in BMS
    *** unaffected by: xRasGrf1(59-1275) [substitution]
    *** inhibited by: xRasGrf1(158-1275) [substitution]
    *** unaffected by: xRasGrf1(mnr)"del-nPH" [substitution]
    *** inhibited by: xRasGrf1(mnr)"del-IQ" [substitution]
    *** source: 15513915-Fig-2b
  *** xRasGrf1[tAb]IP IVGefA(Hras)[3H-GDP] is increased itpo (xTnk2 + xCdc42(G12V)"CA")
    *** cells: HEK293 in BMLS
    *** source: 10882715-Fig-3
  *** xRasGrf1[tAb]IP IVGefA(Hras)[3H-GDP] is increased itpo xTnk2(L543F)"CA"
    *** cells: HEK293 in BMLS
    *** source: 10882715-Fig-4
  *** xRasGrf1[tAb]IP IVGefA(Rac1)[3H-GDP] is increased itpo (xGnb1 + xGng2)
    *** cells: HEK293 in BMLS
    *** source: 10681520-Fig-2a,2b
  *** xRasGrf1[tAb]IP IVGefA(Rac1)[3H-GDP] is unchanged itpo (xTnk2 + xCdc42(G12V)"CA")
    *** cells: HEK293 in BMLS
    *** source: 10882715-Fig-8
  *** xRasGrf1[tAb]IP Yphos[pYAb] is increased itpo (xTnk2 + xCdc42(G12V)"CA")
    *** cells: HEK293 in BMS
    *** inhibited by: HerbimycinA [addition]
    *** source: 10882715-Fig-5b
  *** xRasGrf1[tAb]IP Yphos[pYAb] is increased itpo xCdc42(G12V)"CA"
    *** cells: HEK293 in BMS
    *** source: 10882715-Fig-1a
  *** xRasGrf1[tAb]IP Yphos[pYAb] is increased itpo xTnk2(L543F)"CA"
    *** cells: HEK293 in BMS
    *** source: 10882715-Fig-1b
  *** xRasGrf1[tAb]IP Yphos[pYAb] is unchanged itpo xTnk2
    *** cells: HEK293 in BMS
    *** source: 10882715-Fig-1a
  *** Rass[Ab] snaggedby[WB] rIkzf3[GST] is detectable
    *** cells: TS1<xIL2Ra><xIL2Rb> in BMS "containing IL2" "cytoplasmic-extracts"
    *** enhanced by: IL2-deprivation (tnr) [stress]
    *** source: 10369681-Fig-3a
  *** Rass[Ab] snaggedby[WB] rVav?(mnr)"SH2"[GST] is undetectable
    *** cells: TS1<xIL2Ra><xIL2Rb> in BMS "containing IL2" "cytoplasmic-extracts"
    *** unaffected by: IL2-deprivation (tnr) [stress]
    *** source: 10369681-Fig-3a
*** Rassf1a--
  *** xRassf1a[tAb] copptby[WB] xKras[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 11857081-Fig-1c
  *** xRassf1a[tAb] copptby[WB] xRassf1c[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 11857081-Fig-2e
  *** xRassf1a[tAb] copptby[WB] xRassf5[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 11857081-Fig-2a
  *** xRassf1a[tAb] oligomerization[2TagPpt] is detectable
    *** cells: COS7 in BMS
    *** source: 11857081-Fig-2a,2e
*** Rassf1c--
  *** xRassf1c[tAb] copptby[WB] xHras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T<xRassf1c><xHras(G12V)"CA"> in BMS
    *** inhibited by: xHras(G12V/D38A) [substitution]
    *** inhibited by: xHras(G12V/T35S) [substitution]
    *** inhibited by: xHras(G12V/E37G) [substitution]
    *** inhibited by: xHras(G12V/Y40C) [substitution]
    *** inhibited by: xHras(G12V/D38E) [substitution]
    *** source: 15143186-Fig-6
  *** xRassf1c[tAb] copptby[WB] xHras(G12V)"CA"[tAb] is undetectable
    *** cells: COS7 in BMS
    *** source: 11857081-Fig-1b
  *** xRassf1c[tAb] copptby[WB] xHras[tAb] is undetectable
    *** cells: COS7 in BMS
    *** source: 11857081-Fig-1c
  *** xRassf1c[tAb] copptby[WB] xKras[tAb] is undetectable
    *** cells: COS7 in BMS
    *** source: 11857081-Fig-1c
  *** xRassf1c[tAb] copptby[WB] xRassf1a[tAb] is undetectable
    *** cells: COS7 in BMS
    *** source: 11857081-Fig-2d
  *** xRassf1c[tAb] copptby[WB] xRassf5[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 11857081-Fig-2e
  *** xRassf1c[tAb] oligomerization[2TagPpt] is detectable
    *** cells: COS7 in BMS
    *** source: 11857081-Fig-2e
*** Rassf1d--
  *** xRassf1d[tAb] copptby[WB] xKras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRassf1d[tAb] copptby[WB] xMras(Q71L)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRassf1d[tAb] copptby[WB] xNras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRassf1d[tAb] copptby[WB] xRap1a(G12V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRassf1d[tAb] copptby[WB] xRap2a(G12V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRassf1d[tAb] copptby[WB] xRras(G38V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRassf1d[tAb] copptby[WB] xRras2(G23V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
*** Rassf2--
  *** xRassf2[tAb] copptby[WB] xKras(G12V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRassf2[tAb] copptby[WB] xMras(Q71L)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRassf2[tAb] copptby[WB] xNras(G12V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRassf2[tAb] copptby[WB] xRap1a(G12V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRassf2[tAb] copptby[WB] xRap2a(G12V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRassf2[tAb] copptby[WB] xRras(G38V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRassf2[tAb] copptby[WB] xRras2(G23V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
*** Rassf4--
  *** xRassf4[tAb] copptby[WB] xHras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xHras(G12V/D38A) [substitution]
    *** inhibited by: xHras(G12V/T35S) [substitution]
    *** inhibited by: xHras(G12V/E37G) [substitution]
    *** inhibited by: xHras(G12V/Y40C) [substitution]
    *** inhibited by: xHras(G12V/D38E) [substitution]
    *** source: 15143186-Fig-6
  *** xRassf4[tAb] copptby[WB] xKras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRassf4[tAb] copptby[WB] xMras(Q71L)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRassf4[tAb] copptby[WB] xNras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRassf4[tAb] copptby[WB] xRap1a(G12V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRassf4[tAb] copptby[WB] xRap2a(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRassf4[tAb] copptby[WB] xRras(G38V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRassf4[tAb] copptby[WB] xRras2(G23V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
*** Rassf5--
  *** xRassf5[tAb] copptby[WB] xMras(Q71L)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRassf5[tAb] copptby[WB] xNras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRassf5[tAb] copptby[WB] xRap1a(G12V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRassf5[tAb] copptby[WB] xRap2a(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRassf5[tAb] copptby[WB] xRassf1a[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 11857081-Fig-2a
  *** xRassf5[tAb] copptby[WB] xRras(G38V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRassf5[tAb] copptby[WB] xRras2(G23V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRassf5[tAb] oligomerization[2TagPpt] is detectable
    *** cells: COS7 in BMS
    *** source: 11857081-Fig-2a,2e
*** Rb1--
  *** rRb1(379-928)[32P] phos[32P-ATP] is increased by (rCdk2{act} + rCyclinA2)
    *** cells: none
    *** comment: recombinant proteins were incubated with HELA extract to activate the Cdk2
    *** source: 15241418-Fig-1d
  *** rRb1(379-928)[32P] phos[32P-ATP] is increased by (rCdk2{act} + rCyclinE?)
    *** cells: none
    *** comment: recombinant proteins were incubated with HELA extract to activate the Cdk2
    *** source: 15241418-Fig-1d
  *** rRb1(379-928)[32P] phos[32P-ATP] is increased by (rCdk4{act} + rCyclinD?)
    *** cells: none
    *** comment: recombinant proteins were incubated with HELA extract to activate the Cdk2
    *** source: 15241418-Fig-1b
  *** rRb1(379-928)[32P] phos[32P-ATP] is increased by (rCdk4{act} + rCyclinD?)
    *** cells: none
    *** comment: recombinant proteins were incubated with HELA extract to activate the Cdk2
    *** source: 15241418-Fig-S1b
  *** rRb1(733-928)[32P] phos[32P-ATP] is increased by (rCdk2{act} + rCyclinA2)
    *** cells: none
    *** comment: recombinant proteins were incubated with HELA extract to activate the Cdk2
    *** source: 15241418-Fig-1d
  *** rRb1(733-928)[32P] phos[32P-ATP] is increased by (rCdk2{act} + rCyclinE?)
    *** cells: none
    *** comment: recombinant proteins were incubated with HELA extract to activate the Cdk4
    *** source: 15241418-Fig-1d
  *** rRb1(733-928)[32P] phos[32P-ATP] is increased by (rCdk4{act} + rCyclinD?)
    *** cells: none
    *** comment: recombinant proteins were incubated with HELA extract to activate the Cdk4
    *** source: 15241418-Fig-1b
  *** rRb1(733-928)[32P] phos[32P-ATP] is increased by (rCdk4{act} + rCyclinD?)
    *** cells: none
    *** comment: recombinant proteins were incubated with HELA extract to activate the Cdk4
    *** source: 15241418-Fig-S1b
  *** rRb1[32P] phos[32P-ATP] is increased by (rCyclinD1 + rCdk4)
    *** cells: none
    *** comment: rCyclinD1 and rCdk4 were expressed together in SF9 cells and purified by chromatography
    *** source: 10069453-Fig-1a
  *** rRb1[32P] phos[32P-ATP] is increased by (xCyclinA2[Ab]IP + xCdk2[Ab]IP)
    *** cells: none
    *** IPfrom: SF9 in BMS
    *** comment: CyclinA2 and Cdk2 were cotransfected and IPed as a complex
    *** source: 11359766-Fig-2b
  *** rRb1[32P] phos[32P-ATP] is increased by (xCyclinD?[Ab]IP + xCdk4[Ab]IP)
    *** cells: none
    *** IPfrom: SF9 in BMS
    *** comment: CyclinA2 and Cdk4 were cotransfected and IPed as a complex
    *** source: 11359766-Fig-2b
  *** rRb1[32P] phos[32P-ATP] is increased by Cdk7[Ab]IP
    *** cells: none
    *** IPfrom: hFibros in BMS
    *** comment: inhibited by addition of rCdkn1c + rCyclinD1 to kinase reaction
    *** source: 7629134-Fig-4
  *** Rb1[Ab] copptby[WB] CyclinA1[Ab] is detectable
    *** cells: NB4 in BMS
    *** source: 10022926-Fig-3e
  *** xRb1[Ab] copptby[WB] xCyclinD1[Ab] is detectable
    *** cells: HIGH5<xRb1><xCyclinD1> in BMS
    *** inhibited by: xCyclinA? + xCdk2 [addition]
    *** comment: addition of xCyclinA + xCdk2 caused Rb1-phos [WBMS]
    *** source: 8490963-Fig-1c
  *** xRb1[Ab]IP phos(S780)[phosAb] is increased by (rCyclinD1 + rCdk4)
    *** cells: none
    *** IPfrom: SF9<xRb1> in BMS
    *** comment: rCyclinD1 and rCdk4 were expressed in SF9 cells and purified by chromatograph
    *** inhibited by: xRb1(S780L) [substitution]
    *** source: 9003781-Fig-4a
  *** xRb1[Ab]IP phos(S780)[phosAb] is increased by (rCyclinD2 + rCdk4)
    *** cells: none
    *** IPfrom: SF9<xRb1> in BMS
    *** comment: rCyclinD2 and rCdk4 were expressed in SF9 cells and purified by chromatograph
    *** source: 9003781-Fig-4a
  *** xRb1[Ab]IP phos(S780)[phosAb] is unchanged by (rCyclinD2 + rCdk2)
    *** cells: none
    *** IPfrom: SF9<xRb1> in BMS
    *** comment: rCyclinD2 and rCdk2 were expressed in SF9 cells and purified by chromatograph
    *** source: 9003781-Fig-4a
  *** xRb1[Ab]IP phos(S780)[phosAb] is unchanged by (rCyclinE? + rCdk2)
    *** cells: none
    *** IPfrom: SF9<xRb1> in BMS
    *** comment: rCyclinE? and rCdk2 were expressed in SF9 cells and purified by chromatograph
    *** source: 9003781-Fig-4a
  *** xRb1[Ab]IP phos[32P-ATP] is increased by (rCyclinA? + rCdk2)
    *** cells: none
    *** IPfrom: SF9<xRb1> in BMS
    *** comment: rCyclinA? and rCdk2 were expressed in SF9 cells and purified by chromatograph
    *** source: 9003781-Fig-1c
  *** xRb1[Ab]IP phos[32P-ATP] is increased by (rCyclinD1 + rCdk4)
    *** cells: none
    *** IPfrom: SF9<xRb1> in BMS
    *** comment: rCyclinD1 and rCdk4 were expressed in SF9 cells and purified by chromatograph
    *** source: 9003781-Fig-1c
  *** xRb1[Ab]IP phos[32P-ATP] is increased by (rCyclinE? + rCdk2)
    *** cells: none
    *** IPfrom: SF9<xRb1> in BMS
    *** comment: rCyclinE? and rCdk2 were expressed in SF9 cells and purified by chromatograph
    *** source: 9003781-Fig-1c
  *** xRb1[Ab]IP phos[32P-ATP] is increased by Cdk2[Ab]IP
    *** cells: none
    *** IP1from: SF9<xRb1> in BMS
    *** IP2from: FM3A in BMS
    *** source: 9003781-Fig-3b
  *** xRb1[Ab]IP phos[32P-ATP] is increased by Cdk4[Ab]IP
    *** cells: none
    *** IP1from: SF9<xRb1> in BMS
    *** IP2from: FM3A in BMS
    *** source: 9003781-Fig-3b
  *** xRb1[Ab]IP phos[32P-ATP] is increased by Cdk6[Ab]IP
    *** cells: none
    *** IP1from: SF9<xRb1> in BMS
    *** IP2from: FM3A in BMS
    *** source: 9003781-Fig-3b
  *** Rb1[Ab]IP phos[32P-ATP] is increased by pCdk2
    *** cells: none
    *** IPfrom: ML1 in BMS
    *** source: 1756735-Fig-1b
  *** xRb1[tAb] copptby[WB] Smad4[Ab] is undetectable
    *** cells: COS1 in BMS
    *** unaffected by: Tgfb1 (1 hr) [stim]
    *** source: 12150994-Fig-3a
  *** xRb1[tAb] copptby[WB] Smad23s[Ab] is undetectable
    *** cells: COS1 in BMS
    *** unaffected by: Tgfb1 (1 hr) [stim]
    *** source: 12150994-Fig-3a
*** Rbl1--
  *** rRbl1[32P] phos[32P-ATP] is increased by (rCyclinD1 + rCdk4)
    *** cells: none
    *** comment: rCyclinD1 and rCdk4 were expressed together in SF9 cells and purified by chromatography
    *** source: 10069453-Fig-1b
  *** Rbl1[Ab] copptby[WB] Smad4[Ab] is undetectable
    *** cells: HACAT in BMS
    *** unaffected by: Tgfb1 (1 hr) [stim]
    *** source: 12150994-Fig-3b
  *** Rbl1[Ab] copptby[WB] Smad23s[Ab] is detectable
    *** cells: HACAT in BMS
    *** unaffected by: Tgfb1 (1 hr) [stim]
    *** inhibited by: xE2f4 + xE2f5 [addition]
    *** source: 12150994-Fig-3b
  *** xRbl1[Ab]IP phos[32P-ATP] is increased by (rCyclinA? + rCdk2)
    *** cells: none
    *** IPfrom: SF9<xRbl1> in BMS
    *** comment: rCyclinA? and rCdk2 were expressed in SF9 cells and purified by chromatograph
    *** source: 9003781-Fig-1c
  *** xRbl1[Ab]IP phos[32P-ATP] is increased by (rCyclinD1 + rCdk4)
    *** cells: none
    *** IPfrom: SF9<xRbl1> in BMS
    *** comment: rCyclinD1 and rCdk4 were expressed in SF9 cells and purified by chromatograph
    *** source: 9003781-Fig-1c
  *** xRbl1[tAb] copptby[WB] Smad4[Ab] is undetectable
    *** cells: COS1 in BMS
    *** unaffected by: Tgfb1 (1 hr) [stim]
    *** source: 12150994-Fig-3a
  *** xRbl1[tAb] copptby[WB] Smad23s[Ab] is detectable
    *** cells: COS1 in BMS
    *** unaffected by: Tgfb1 (1 hr) [stim]
    *** source: 12150994-Fig-3a
*** Rbl2--
  *** xRbl2[tAb] copptby[WB] Smad4[Ab] is undetectable
    *** cells: COS1 in BMS
    *** unaffected by: Tgfb1 (1 hr) [stim]
    *** source: 12150994-Fig-3a
  *** xRbl2[tAb] copptby[WB] Smad23s[Ab] is undetectable
    *** cells: COS1 in BMS
    *** unaffected by: Tgfb1 (1 hr) [stim]
    *** source: 12150994-Fig-3a
  *** Rbx1[Ab] copptby[WB] xFbxo11[tAb] is detectable
    *** cells: HEK293<xFbxo11> in BMS "nuclear extracts"
    *** inhibited by: xFbxo11(del(152-197)) [substitution]
    *** source: 17098746-Fig-2b
  *** REAP-reporter[Luc] is increased irt PMA (tnr)
    *** cells: JURKATT<Pten~null> in BMS
    *** inhibited by: xTpl2(mnr)"KD" [addition]
    *** source: 12138205-Fig-1b
  *** REAP-reporter[Luc] is increased itpo (xTpl2 + xAkt1(myr))
    *** cells: HUT78 in BMS
    *** reqs: xTpl2 [omission]
    *** reqs: xAkt1(myr) [omission]
    *** inhibited by: xAkt1 [substitution]
    *** source: 12138205-Fig-1c
  *** REAP-reporter[Luc] is increased itpo (xTpl2 + xAkt1(myr))
    *** cells: JURKATT<Pten~null> in BMS
    *** unaffected by: xPten [addition]
    *** source: 12138205-Fig-1d
  *** REAP-reporter[Luc] is increased itpo (xTpl2 + xAkt1)
    *** cells: JURKATT<Pten~null> in BMS
    *** inhibited by: xPten [addition]
    *** source: 12138205-Fig-1d
  *** REAP-reporter[Luc] is increased itpo xTpl2
    *** cells: JURKATT<Pten~null> in BMS
    *** enhanced by: xAkt1 [addition]
    *** source: 12138205-Fig-1a
  *** REAP-reporter[Luc] is increased itpo xTpl2
    *** cells: JURKATT<Pten~null> in BMS
    *** inhibited by: xPten [addition]
    *** source: 12138205-Fig-1d
  *** REAP-reporter[Luc] is increased itpo xTpl2
    *** cells: JURKATT<Pten~null> in BMS
    *** inhibited by: xTpl2(mnr)"delC" [substitution]
    *** partially inhibited by: xTpl2(mnr)"M30" [substitution]
    *** inhibited by: xTpl2(mnr)"Q104" [substitution]
    *** source: 12138205-Fig-2c
  *** REAP-reporter[Luc] is increased itpo xTpl2
    *** cells: JURKATT<Pten~null> in BMS
    *** unaffected by: xTpl2(del(424-468)) [substitution]
    *** inhibited by: xTpl2(del(397-468)) [substitution]
    *** source: 12138205-Fig-3c
  *** REAP-reporter[Luc] is increased itpo xTpl2
    *** cells: JURKATT<Pten~null> in BMS
    *** unaffected by: xTpl2(S413A) [substitution]
    *** inhibited by: xTpl2(S400A) [substitution]
    *** inhibited by: xTpl2(S400A/S413A) [substitution]
    *** source: 12138205-Fig-5a
  *** REAP-reporter[Luc] is unchanged itpo xAkt1
    *** cells: JURKATT<Pten~null> in BMS
    *** source: 12138205-Fig-1a
*** Rel--
  *** xRel(181-361)"delCdelN"[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: HEK293<xRel(181-361)"delCdelN"> in BMS
    *** inhibited by: xIkba [addition]
    *** source: 9566883-Fig-2a
  *** xRel(del(292-295))"delNLS"[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: HEK293<xRel(del(292-295))"delNLS"> in BMS
    *** source: 9566883-Fig-3a
  *** Rel[Ab] copptby[WB] Nfkb1[Ab] is detectable
    *** cells: HELA in BMS
    *** comment: more Rel coppts with Nfkb1 than with Tpl2
    *** source: 9950430-Fig-3a
  *** Rel[Ab] copptby[WB] Tpl2[Ab] is detectable
    *** cells: HELA in BMS
    *** source: 9950430-Fig-3a
  *** Rel[Ab] copptby[WB] xIkbb[tAb] is detectable
    *** cells: JURKAT<Pten~null> in BMS
    *** source: 15024091-Fig-1c
  *** Rel[Ab] oligo-binding[EMSA] is unchanged itpo xTraf2
    *** cells: HEK293 in BMS "nuclear-extracts"
    *** source: 7544915-Fig-1
*** Rela--
  *** rRela(1-306)[GST] phos[32P-ATP] is unchanged by xIkke[Ab]IP
    *** cells: none
    *** IPfrom: HEK293<xIkke> in BMS
    *** source: 17003035-Fig-5d
  *** xRela(189-337)"delCdelN"[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: HEK293<xRela(189-337)"delCdelN"> in BMS
    *** inhibited by: xIkba [addition]
    *** source: 9566883-Fig-2a
  *** rRela(428-551)[GST] phos[32P-ATP] is increased by xIkke[Ab]IP
    *** cells: none
    *** IPfrom: HEK293<xIkke> in BMS
    *** enhanced by: Tnf [pretreatment]
    *** source: 17003035-Fig-5d
  *** xRela(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo (xTLR4 + xCd4)
    *** cells: HEK293 in BMS
    *** inhibited by: xRela(S536A) [substitution]
    *** source: 15849198-Fig-2a
  *** xRela(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo (xTLR4 + xCd4)
    *** cells: HEK293<xTLR4> in BMS
    *** inhibited by: xBtk(K430R)"DN" [addition] no-bkg-control
    *** source: 15849198-Fig-2d
  *** xRela(TAD)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xBtk
    *** cells: HEK293 in BMS
    *** inhibited by: xRela(S536A) [substitution]
    *** source: 15849198-Fig-2a
  *** rRela[35S] boundby[WB] rKpna1[35S] is detectable
    *** cells: none
    *** inhibited by: rRela(K301A/R302A/K303A)"NLS-mut" [substitution]
    *** source: 15677444-Fig-6b
  *** rRela[35S] boundby[WB] rKpna1[35S] is detectable
    *** cells: none
    *** source: 15677444-Fig-5a
  *** rRela[35S] boundby[WB] rKpna3[35S] is detectable
    *** cells: none
    *** inhibited by: rIkba [addition]
    *** partially inhibited by: rIkba + rNfkb1 [addition]
    *** source: 15677444-Fig-5b
  *** rRela[35S] boundby[WB] rKpna3[35S] is detectable
    *** cells: none
    *** inhibited by: rRela(K301A/R302A/K303A)"NLS-mut" [substitution]
    *** source: 15677444-Fig-6a
  *** rRela[35S] boundby[WB] rKpna3[35S] is detectable
    *** cells: none
    *** source: 15677444-Fig-5a
  *** rRela[35S] boundby[WB] rKpna3[35S] is detectable
    *** cells: none
    *** unaffected by: rKpna3(mnr)"ARM3" [substitution]
    *** inhibited by: rKpna3(mnr)"ARM7+8" [substitution]
    *** inhibited by: rKpna3(mnr)"ARM3+8" [substitution]
    *** source: 15677444-Fig-7d
  *** rRela[35S] boundby[WB] rKpna5[35S] is detectable
    *** cells: none
    *** source: 15677444-Fig-5a
  *** rRela[35S] boundby[WB] rKpna6[35S] is detectable
    *** cells: none
    *** source: 15677444-Fig-5a
  *** rRela[35S] boundby[WB] rKpnb1[35S] is detectable
    *** cells: none
    *** source: 15677444-Fig-5a
  *** rRela[35S] upshift[WBMS] is increased by (rUbiq + rUbe1 + rUbe2d1)
    *** cells: none
    *** source: 14690596-Fig-6c
  *** Rela[Ab] boundto(CcL2-gene)[ChIP] is detectable
    *** cells: mEFs in BMLS
    *** reqs: Jun [KO]
    *** comment: samples were first ppt with anti-Jun Ab
    *** source: 18443042-Fig-10c
  *** Rela[Ab] boundto(CcL2-gene)[ChIP] is detectable
    *** cells: mEFs in BMLS
    *** reqs: Jun [KO]
    *** inhibited by: kJun(S63A/S73A) [substitution]
    *** source: 18443042-Fig-10b
  *** Rela[Ab] boundto(CcL2-gene)[ChIP] is detectable
    *** cells: mEFs in BMS
    *** reqs: Jun [KO]
    *** source: 18443042-Fig-8b
  *** Rela[Ab] copptby[WB] Ikba[Ab] is decreased itpo xPin1
    *** cells: HELA in BMS
    *** source: 14690596-Fig-3i
  *** Rela[Ab] copptby[WB] Nfkb1[Ab] is detectable
    *** cells: HELA in BMS
    *** comment: more Rela coppts with Nfkb1 than with Tpl2
    *** source: 9950430-Fig-3a
  *** Rela[Ab] copptby[WB] Tpl2[Ab] is detectable
    *** cells: HELA in BMS
    *** source: 9950430-Fig-3a
  *** Rela[Ab] copptby[WB] xFoxp3[tAb] is detectable
    *** cells: HEK293T<xFoxp3> in BMS "treated with Tnf for 1 hr"
    *** source: 15790681-Fig-4b
  *** xRela[Ab] copptby[WB] xFoxp3[tAb] is detectable
    *** cells: HEK293T<xRela><xFoxp3> in BMS
    *** source: 15790681-Fig-4a
  *** xRela[Ab] copptby[WB] xMsk1[tAb] is increased itpo (xMkk6 + xP38?)
    *** cells: HEK293 in BMS
    *** inhibited by: xMsk1(mnr)"KD" [substitution]
    *** source: 12628924-Fig-6a
  *** Rela[Ab] infraction(nuclear)[WB] is detectable
    *** cells: MCF7 in BMS
    *** reqs: Muc1 [RNAi]
    *** source: 18037881-Fig-1b
  *** Rela[Ab] infraction(nuclear)[WB] is detectable
    *** cells: ZR751 in BMS
    *** partially reqs: Muc1 [RNAi]
    *** source: 18037881-Fig-1b
  *** Rela[Ab] infraction(nuclear)[WB] is increased itpo (xTak1 + xTab1)
    *** cells: HELA in BMS
    *** inhibited by: xTak1(T187A) [substitution]
    *** inhibited by: xTak1(K63W)"KD" [substitution]
    *** source: 15590691-Fig-1b
  *** Rela[Ab] infraction(nuclear)[WB] is increased itpo xMuc1
    *** cells: HCT116 in BMS
    *** source: 18037881-Fig-1a
  *** Rela[Ab] infraction(nuclear)[WB] is increased itpo xMuc1
    *** cells: HELA in BMS
    *** source: 18037881-Fig-1a
  *** Rela[Ab] locatedin(cytoplasm)[IHC] is detectable
    *** cells: rSchwann in BMS
    *** source: 8614802-Fig-1a
  *** Rela[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: HELA<xTpl2> in BMS
    *** inhibited by: xTpl2(mnr)"KD" [substitution]
    *** inhibited by: xTpl2(S400A) [substitution]
    *** source: 12138205-Fig-7
  *** Rela[Ab] locatedin(nucleus)[IHC] is increased itpo xTbk1
    *** cells: COS7 in BMS
    *** source: 10783893-Fig-2b
  *** Rela[Ab] oligo-binding[ELISA] is increased itpo (xIL12a + xIL12b) 
    *** cells: TC71 in BMS
    *** source: 16380506-Fig-7a
  *** Rela[Ab] oligo-binding[ELISA] is increased itpo xIkke
    *** cells: HEK293 in BMS
    *** source: 16199137-Fig-5b
  *** Rela[Ab] oligo-binding[EMSA] is increased itpo xIkk2
    *** cells: HEK293T in BMS
    *** inhibited by: xIkk2(mnr)"KD" [substitution]
    *** source: 10783893-Fig-3b
  *** Rela[Ab] oligo-binding[EMSA] is increased itpo xPin1
    *** cells: HEK293T in BMS
    *** source: 14690596-Fig-2c
  *** Rela[Ab] oligo-binding[EMSA] is increased itpo xTbk1
    *** cells: HEK293 in BMS "nuclear-extracts"
    *** inhibited by: xTbk1(K38A) [substitution]
    *** source: 10581243-Fig-2a
  *** Rela[Ab] oligo-binding[EMSA] is increased itpo xTbk1
    *** cells: HEK293T in BMS
    *** inhibited by: xTbk1(K38M)"KD" [substitution]
    *** source: 10783893-Fig-3b
  *** Rela[Ab] oligo-binding[EMSA] is increased itpo xTradd
    *** cells: HEK293 in BMS
    *** source: 7758105-Fig-5a
  *** Rela[Ab] oligo-binding[EMSA] is increased itpo xTraf2
    *** cells: HEK293 in BMS "nuclear-extracts"
    *** source: 7544915-Fig-1
  *** Rela[Ab] oligo-binding[EMSA] is increased itpo xTrpc4ap
    *** cells: NIH3T3 in BMS
    *** source: 14585990-Fig-4b
  *** Rela[Ab] prot-stability[CHX-WB] is decreased itpo xSocs1
    *** cells: NotReported in BMS
    *** reversed by: xPin1 [addition]
    *** source: 14690596-Fig-8c
  *** Rela[Ab] snaggedby[WB] xStat1(K410Q/K413Q)[Ab]IP is detectable
    *** cells: SKMEL37 in BMS "nuclear-extracts"
    *** IPfrom: U3A<Stat1~null><xStat1(K410Q/K413Q)> in BMS
    *** inhibited by: xStat1(K410R/K413R) [substitution]
    *** source: 16481475-Fig-7d
  *** xRela[Ab]IP phos[32Pi] is increased itpo (xMkk6 + xP38? + xMsk1)
    *** cells: HEK293 in BMS
    *** reqs: xMkk6 and/or xP38? [omission]
    *** inhibited by: xMsk1(mnr)"KD" [substitution]
    *** source: 12628924-Fig-5a
  *** Rela[Ab]IP upshift[WBMS] is increased by (rUbiq + rUbe2d3 + rUbe1)
    *** cells: none
    *** IPfrom: HELA in BMS "treated with ALLN (tnr) and Tnf (10 min)"
    *** reqs: rUbe1 [omission]
    *** comment: inhibited by rPeptide "DRHDS[PO3]GLDS[PO3]M" [addition]
    *** comment: unaffected by rPeptide "DRHDEGLDEM" [addition]
    *** source: 9859996-Fig-1a
  *** xRela[Gal4-DBD] Gal4-reporter[Luc] is decreased itpo xFoxp3
    *** cells: HEK293T in BMS
    *** source: 15790681-Fig-4d
  *** xRela[Gal4-DBD] Gal4-reporter[Luc] is decreased itpo xFoxp3
    *** cells: mCD4TCs in BMS "treated with anti-Cd3 + anti-Cd28 (24 hr)"
    *** source: 15790681-Fig-5c
  *** xRela[Gal4-DBD] Gal4-reporter[Luc] is decreased itpo xFoxp3
    *** cells: mCD4TCs<Foxp3~fmut> in BMS "treated with anti-Cd3 + anti-Cd28 (24 hr)"
    *** source: 15790681-Fig-5d
  *** xRela[Gal4-DBD] Gal4-reporter[Luc] is increased itao Foxp3 [fmut] 
    *** cells: mCD4TCs in BMS "treated with anti-Cd3 + anti-Cd28 (24 hr)"
    *** source: 15790681-Fig-5d
  *** xRela[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xPias1
    *** cells: HEK293T in BMS
    *** source: 15657437-Fig-7d
  *** Rela[phosAb] phos(S536)[phosAb] is increased itpo (xTak1 + xTab1)
    *** cells: HEK293 in BMS
    *** reqs: xTab1 [omission]
    *** inhibited by: xTak1(mnr)"KD" [substitution]
    *** source: 12842894-Fig-5a
  *** Rela[phosAb] phos(S536)[phosAb] is increased itpo xIkke
    *** cells: HEK293 in BMS
    *** source: 16199137-Fig-3b
  *** xRela[phosAb] phos(S536)[phosAb] is increased itpo xIkke
    *** cells: HEK293<xIL1R1> in BMS
    *** source: 15489227(D)
  *** Rela[phosAb] phos(S536)[phosAb] is increased itpo xTp53
    *** cells: SAOS2 in BMS
    *** enhanced by: Etoposide [addition]
    *** source: 15073170-Fig-6b,7b
  *** rRela[tAb] boundby[WB] rTaf9b[GST] is detectable
    *** cells: none
    *** inhibited by: rAes [addition]
    *** source: 15489227(D)
  *** xRela[tAb] copptby[WB] xHdac1[tAb] is undetectable
    *** cells: COS7 in BMS
    *** source: 11533489-Fig-3a
  *** xRela[tAb] copptby[WB] xHdac3[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 11533489-Fig-3a
  *** xRela[tAb] copptby[WB] xPias4[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 17606919-Fig-1a
  *** xRela[tAb] copptby[WB] xSocs1[tAb] is detectable
    *** cells: mEFs in BMS
    *** source: 14690596-Fig-7c
  *** xRela[tAb] copptby[WB] xTnfaip3[tAb] is undetectable
    *** cells: HEK293T<xTnfaip3><xRela> in BMS
    *** source: 21220427-Fig-8a
  *** xRela[tAb] copptby[WB] xUbiq[tAb] is increased itpo xSocs1
    *** cells: HELA<xUbe2d1> in BMS "treated with (MG132 + MG115)"
    *** inhibited by: xPin1 [addition]
    *** source: 14690596-Fig-6f
  *** xRela[tAb] infraction(nuclear)[WB] is increased itpo xCebpb
    *** cells: HELA<xRela> in BMS
    *** source: 19733238-Fig-2g
  *** xRela[tAb] locatedin(cytoplasm)[IHC] is detectable
    *** cells: HUH7<xRela> in BMS "treated with LMB"
    *** unaffected by: xRela(K301A/R302A/K303A)"NLS-mut" [substitution]
    *** source: 15677444-Fig-6c
  *** xRela[tAb] locatedin(cytoplasm)[IHC] is detectable
    *** cells: HUH7<xRela> in BMS "treated with LMB"
    *** unaffected by: xRela(K301A/R302A/K303A)"NLS-mut" [substitution]
    *** source: 15677444-Fig-8
  *** xRela[tAb] locatedin(nucleus)[IHC] is increased itpo xPin1
    *** cells: HELA in BMS
    *** source: 14690596-Fig-2d
  *** xRela[tAb] snaggedby[WB] rIkba[GST] is decreased itpo xEp300
    *** cells: HEK293T in BMS
    *** reversed by: xHdac3 [addition]
    *** source: 11533489-Fig-3c
  *** xRela[tAb] snaggedby[WB] rPin1[GST] is detectable
    *** cells: HELA in BMS
    *** inhibited by: xRela(T254A) [substitution]
    *** unaffected by: xRela(S316A) [substitution]
    *** source: 14690596-Fig-3f
  *** xRela[tAb]IP acetyl[3H-acetate-CHX] is detectable
    *** cells: COS7 in BMS
    *** inhibited by: xHdac3 [addition]
    *** source: 11533489-Fig-2a
  *** xRela[tAb]IP acetyl[3H-acetate-CHX] is detectable
    *** cells: COS7 in BMS
    *** unaffected by: xHdac1 [addition]
    *** source: 11533489-Fig-2a
  *** xRela[tAb]IP phos[32Pi] is increased itpo (xIkk1 + xIkk2 + xNik)
    *** cells: HELA in BMS
    *** reqs: xNik [omission]
    *** source: 10521409-Fig-5a
  *** xRela[tAb]IP phos[32Pi] is increased itpo (xMkk6 + xP38?)
    *** cells: HEK293 in BMS
    *** inhibited by: xRela(S276A) [substitution]
    *** source: 12628924-Fig-5b
*** Relb--
  *** Relb[Ab] copptby[WB] Ikba[Ab] is undetectable
    *** cells: mSpBCs in BMS
    *** source: 12374738-Fig-6a
  *** Relb[Ab] copptby[WB] Nfkb2[Ab] is detectable
    *** cells: mSpBCs in BMS
    *** comment: coppt Nfkb2 is 52 kD and 100kD
    *** source: 12374738-Fig-6a
  *** Relb[Ab] oligo-binding[EMSA] is unchanged itpo xTraf2
    *** cells: HEK293 in BMS "nuclear-extracts"
    *** source: 7544915-Fig-1
  *** rReps2[tAb] boundby[WB] rAsap1(1002-1132)[tAb] is detectable
    *** cells: none
    *** source: 12149250-Fig-3a
  *** xReps2[tAb] copptby[WB] xAsap1(1032-1129)"SH3"[tAb] is detectable
    *** cells: COS<xReps2><xAsap1(1032-1129)"SH3"> in BMS
    *** source: 12149250-Fig-2a
  *** xReps2[tAb] copptby[WB] xAsap1[tAb] is detectable
    *** cells: CHO<xInsR><xReps2><xRalbp1> in BMS
    *** source: 12149250-Fig-2a
  *** xReps2[tAb] copptby[WB] xPxn[GST] is detectable
    *** cells: CHO<xInsR><xReps2><xPxn> in BMS
    *** enhanced by: xAsap1 [addition]
    *** source: 12149250-Fig-6a
  *** xReps2[tAb] copptby[WB] xRalbp1[tAb] is detectable
    *** cells: CHO<xInsR><xReps2><xRalbp1> in BMS
    *** unaffected by: xReps2(P423A/P426A) [substitution]
    *** source: 12149250-Fig-5b
  *** xReps2[tAb] copptby[WB] xRalbp1[tAb] is detectable
    *** cells: COS<xReps2><xRalbp1> in BMS
    *** source: 12149250-Fig-2a
  *** rRerg GDP-dissociation[Mant-GDP] is unchanged by rRasGef1a
    *** cells: none
    *** source: 19645719-Fig-1c
  *** rRerg GDP-dissociation[Mant-GDP] is unchanged by rRasGef1b
    *** cells: none
    *** source: 19645719-Fig-1c
  *** rRgl3(RBD) boundby[WB] rRab1a{GTPgS}[GST] is undetectable
    *** cells: none
    *** unaffected by: rRab1a{GDP} [substitution]
    *** source: 10869344-Fig-3a
  *** rRgl3(RBD) boundby[WB] rRheb{GTPgS}[GST] is undetectable
    *** cells: none
    *** unaffected by: rRheb{GDP} [substitution]
    *** source: 10869344-Fig-3a
  *** rRgl3[35S] boundby[WB] rRheb{GTPgS}[GST] is undetectable
    *** cells: none
    *** unaffected by: rRheb{GDP} [substitution]
    *** source: 10869344-Fig-4
  *** xRgl3[tAb] copptby[WB] xCdc42(G12V)"CA"[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 11313946-Fig-3c
  *** xRgl3[tAb] copptby[WB] xMras(G22V)"CA"[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 11313946-Fig-3c
  *** xRgl3[tAb] copptby[WB] xMras(Q71L)"CA"[tAb] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xMras [substitution]
    *** source: 11313946-Fig-3c
  *** rRgs19[35S] boundby[WB] rRgs19ip1(125-333)[GST] is detectable
    *** cells: none
    *** source: 11251075-Fig-6b
  *** rRgs19[35S] boundby[WB] rRgs19ip1[GST] is detectable
    *** cells: none
    *** source: 11251075-Fig-6a
  *** rRgs19[35S] boundby[WB] rTrka(448-552)[GST] is undetectable
    *** cells: none
    *** source: 11251075-Fig-6a
  *** rRgs19[35S] boundby[WB] rTrka[GST] is undetectable
    *** cells: none
    *** source: 11251075-Fig-6b
  *** xRgs19[Ab] copptby[WB] xRgs19ip1[Ab] is detectable
    *** cells: HEK293<xRgs19ip1><xRgs19> in BMS
    *** inhibited by: xRgs19ip1(L142C/G143E) [substitution]
    *** source: 11251075-Fig-7a
  *** xRgs19[Ab] copptby[WB] xRgs19ip1[Ab] is detectable
    *** cells: HEK293<xRgs19ip1><xRgs19> in BMS
    *** source: 11251075-Fig-5b
  *** xRgs19[Ab] copptby[WB] xRgs19ip1[tAb] is detectable
    *** cells: HEK293<xRgs19ip1><xRgs19> in BMS
    *** inhibited by: xRgs19ip1(L142C/G143E) [substitution]
    *** source: 11251075-Fig-7a
  *** xRgs19[Ab] copptby[WB] xTrka[Ab] is detectable
    *** cells: HEK293<xRgs19ip1><xRgs19><xTrka> in BMS
    *** source: 11251075-Fig-5c
  *** rRgs19ip1(81-333)[35S] boundby[WB] rTrka(448-552)[GST] is detectable
    *** cells: none
    *** unaffected by: rRgs19ip1(125-333) [substitution]
    *** inhibited by: rRgs19ip1(226-333) [substitution]
    *** inhibited by: rRgs19ip1(1-124) [substitution]
    *** unaffected by: rRgs19ip1(125-225)"PDZ" [substitution]
    *** source: 11251075-Fig-3
  *** xRgs19ip1[Ab] copptby[WB] xTrka[Ab] is detectable
    *** cells: HEK293<xRgs19ip1><xRgs19><xTrka> in BMS
    *** source: 11251075-Fig-5c
  *** xRgs19ip1[Ab] copptby[WB] xTrka[Ab] is detectable
    *** cells: HEK293<xRgs19ip1><xTrka> in BMS
    *** unaffected by: xRgs19ip1(L142C/G143E) [substitution]
    *** source: 11251075-Fig-7b
  *** xRgs19ip1[Ab] copptby[WB] xTrka[Ab] is detectable
    *** cells: HEK293T<xRgs19ip1><xTrka> in BMS
    *** source: 11251075-Fig-1
  *** xRgs19ip1[Ab] copptby[WB] xTrka[Ab] is detectable
    *** cells: HEK293T<xRgs19ip1><xTrka> in BMS
    *** unaffected by: xTrka(1-522) [substitution]
    *** unaffected by: xTrka(1-501) [substitution]
    *** unaffected by: xTrka(1-493) [substitution]
    *** partially inhibited by: xTrka(1-472) [substitution]
    *** inhibited by: xTrka(1-452) [substitution]
    *** source: 11251075-Fig-2
  *** xRgs19ip1[Ab] copptby[WB] xTrkb[Ab] is detectable
    *** cells: HEK293T<xRgs19ip1><xTrkb> in BMS
    *** source: 11251075-Fig-1
  *** rRheb GDP-dissociation[3H-GDP] is unchanged by rPlce1
    *** cells: none
    *** source: 11395506-Fig-3
  *** rRheb GDP-dissociation[Mant-GDP] is unchanged by rRasGef1a
    *** cells: none
    *** source: 19645719-Fig-1c
  *** rRheb GDP-dissociation[Mant-GDP] is unchanged by rRasGef1b
    *** cells: none
    *** source: 19645719-Fig-1c
  *** rRheb GTP-hydrolysis[32P-release] is increased by (xTsc1[tAb]IP + xTsc2[tAb]IP)
    *** cells: none
    *** IPfrom: HEK293<xTsc1><xTsc2> in BMS
    *** reqs: both [omission]
    *** source: 12906785-Fig-6
*** Rheb--
  *** Rheb[Ab]IP GTP-association[TLC] is increased itao Tsc2 [KO]
    *** cells: mEFs in BMLS
    *** source: 12820960-Fig-1b
  *** xRheb[GST]IP GTP-association[TLC] is detectable
    *** cells: HEK293T<xRheb> in BMLS
    *** enhanced by: xRheb(T38M) [substitution]
    *** unaffected by: xRheb(I39K) [substitution]
    *** inhibited by: xRheb(C181S) [substitution]
    *** comment: xRheb(S20N) did not bind either GDP or GTP
    *** comment: xRheb(D60I) did not bind either GDP or GTP
    *** source: 15854902-Fig-1b
  *** xRheb[tAb] copptby[WB] xBnip3[tAb] is detectable
    *** cells: HEK293<xBnip3><xRheb> in BMS
    *** inhibited by: xRheb(C181S) [substitution]
    *** source: 17928295-Fig-1c
  *** Rheb[tAb] copptby[WB] xBnip3[tAb] is detectable
    *** cells: HEK293<xBnip3><xRheb> in BMS
    *** unaffected by: xBnip3(31-194)"delN30" [substitution]
    *** unaffected by: xBnip3(del(110-15))"delBH3" [substitution]
    *** unaffected by: xBnip3(del(115-126))"delCD" [substitution]
    *** inhibited by: xBnip3(115-194)"delN114" [substitution]
    *** inhibited by: xBnip3(1-163)"delTM" [substitution]
    *** source: 17928295-Fig-1c
  *** xRheb[tAb] copptby[WB] xRaf1[tAb] is undetectable
    *** cells: HEK293 in BMLS
    *** unaffected by: Serum (10 min) [stim]
    *** source: 16803888-Fig-2a
  *** xRheb[tAb]IP GTP-association[TLC] is decreased itpo (xTsc1 + xTsc2)
    *** cells: COS7<xRheb> in BMS
    *** reversed by: xRheb(N1643K) [substitution]
    *** source: 12820960-Fig-4b
  *** xRheb[tAb]IP GTP-association[TLC] is decreased itpo xBnip3
    *** cells: HEK293<xRheb> in BMS
    *** reversed by: xBnip3(31-194)"delN30" [substitution]
    *** reversed by: xBnip3(1-163)"delTM" [substitution]
    *** source: 17928295-Fig-3c
  *** xRheb[tAb]IP GTP-association[TLC] is decreased itpo xTsc2
    *** cells: COS7<xRheb> in BMS
    *** enhanced by: xTsc1 [addition]
    *** source: 12820960-Fig-1c
  *** xRheb[tAb]IP GTP-association[TLC] is decreased itpo xTsc2
    *** cells: COS7<xRheb> in BMS
    *** enhanced by: xTsc1 [addition]
    *** source: 12820960-Fig-4b
  *** xRheb[tAb]IP GTP-association[TLC] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xRheb(C181S) [substitution]
    *** enhanced by: xRheb(Q41L) [substitution]
    *** source: 15340059-Fig-2a
  *** xRheb[tAb]IP GTP-association[TLC] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xRheb(R15V) [substitution]
    *** unaffected by: xRheb(R15G) [substitution]
    *** inhibited by: xRheb(R15P) [substitution]
    *** source: 15340059-Fig-1b
  *** xRheb[tAb]IP GTP-association[TLC] is detectable-but unchanged itpo xTsc1
    *** cells: HEK293T in BMLS
    *** source: 12842888-Fig-3
  *** xRheb[tAb]IP GTP-association[TLC] is unchanged itpo xRap1Gap
    *** cells: COS7<xRheb> in BMS
    *** source: 12820960-Fig-1c
  *** xRheb[tAb]IP GTP-association[TLC] is unchanged itpo xTsc1
    *** cells: COS7<xRheb> in BMS
    *** source: 12820960-Fig-1c
  *** rRheb{NucFree}[GST] boundby[WB] rRgl3(1-557)"delRBD"[tAb] is detectable
    *** cells: none
    *** source: 10869344-Fig-6a
  *** rRhoa GDP-dissociation[3H-GDP] is unchanged by rArhGef4
    *** cells: none
    *** unaffected by: rApc(mnr)"Arm-domain" [addition]
    *** source: 10947987-Fig-3c
  *** rRhoa GDP-dissociation[3H-GDP] is unchanged by rRalGds
    *** cells: none
    *** source: 8094051-Fig-5
  *** rRhoa GDP-dissociation[Mant-GDP] is increased by rRgnef(mnr)"DH/PH"
    *** cells: none
    *** source: 17214551-Fig-2e
  *** rRhoa GDP-dissociation[Mant-GDP] is unchanged by rArhGef4(233-448)"DH"
    *** cells: none
    *** source: 17214551-Fig-2e
  *** rRhoa GTP-association[35S-GTPgS] is increased by rAbr(104-383)
    *** cells: none
    *** source: 9659915-Fig-6a
  *** rRhoa GTP-association[35S-GTPgS] is increased by rArhGef6(155-545)
    *** cells: none
    *** source: 9659915-Fig-6a
  *** rRhoa GTP-association[Mant-GTP] is increased by rDbs(271-632)"DH/PH"
    *** cells: none
    *** source: 17704816-Fig-1b
  *** rRhoa GTP-association[Mant-GTP] is unchanged by rArhGef4(271-632)"DH/PH"
    *** cells: none
    *** source: 17704816-Fig-1b
  *** rRhoa GTP-association[Mant-GTP] is unchanged by rArhGef4(271-632)"DH/PH"
    *** cells: none
    *** source: 17704816-Fig-S1
  *** rRhoa GTP-hydrolysis[32P-GTP] is unchanged by rSipa1
    *** cells: none
    *** source: 9346962-Fig-3a
  *** rRhoa GTP-hydrolysis[Pi-release] is increased by rArhGap1
    *** cells: none
    *** source: 10843989-Fig-9c
*** Rhoa--
  *** xRhoa(G14V)[tAb] snaggedby[WB] rElmo2(1-362)[GST] is undetectable
    *** cells: HEK293T<xRhoa(G14V)> in BMS
    *** source: 12879077-Fig-1b
  *** xRhoa(G14V)[tAb] snaggedby[WB] rPak1(mnr)"CRIB"[GST] is undetectable
    *** cells: HEK293T<xRhoa(G14V)> in BMS
    *** source: 12879077-Fig-1b
  *** xRhoa(G14V)[tAb] snaggedby[WB] rRtkn(mnr)"RBD"[GST] is detectable
    *** cells: HEK293T<xRhoa(G14V)> in BMS
    *** source: 12879077-Fig-1b
  *** rRhoa[Ab] boundby[WB] rArhGef4(mnr)"APC-binding-mutant"[Resin] is detectable
    *** cells: none
    *** source: 10947987-Fig-3a
  *** Rhoa[Ab] GTP-association[BDPD] is detectable
    *** cells: NIH3T3<xNckipsd> in BMS "membrane-fractions"
    *** inhibited by: xDiaph1(mnr)"CA" [addition]
    *** unaffected by: xDiaph1(mnr)"CA/dFH1" [addition]
    *** source: 14765113-Fig-4c
  *** Rhoa[Ab] GTP-association[BDPD] is detectable
    *** cells: NIH3T3<xNckipsd> in BMS "membrane-fractions"
    *** unaffected by: xNckipsd(del(170-249))"dPro" [substitution]
    *** source: 14765113-Fig-4c
  *** Rhoa[Ab] GTP-association[BDPD] is increased itao Mlk3 [RNAi]
    *** cells: A549 in BMLS
    *** source: 18851832-Fig-3a
  *** Rhoa[Ab] GTP-association[BDPD] is increased itpo xTnk2(L543F)"CA"
    *** cells: COSM6<xDbl> in BMLS
    *** source: 10652228-Fig-3b
  *** xRhoa[tAb] GTP-association[BDPD] is decreased itpo xNckipsd
    *** cells: HEK293T<xRhoa> in BMS "membrane-fractions"
    *** reversed by: xNckipsd(del(170-249))"dPro" [substitution]
    *** source: 14765113-Fig-3c
  *** xRhoa[tAb] GTP-association[BDPD] is unchanged itpo xDock4
    *** cells: HEK293T in BMS
    *** unaffected by: xDock4(P1718L)"Crk-BS-mut" [substitution]
    *** source: 12628187-Fig-4c
  *** xRhoa[tAb] GTP-association[BDPD] is unchanged itpo xVav2
    *** cells: NIH3T3 in BMS
    *** source: 11448999-Fig-1d
  *** xRhoa[tAb]IP GTP-association[TLC] is increased itpo xHras(S17N)"DN"
    *** cells: HEK293T in BMS
    *** source: 11948427-Fig-4d
  *** rRhob GDP-dissociation[3H-GDP] is unchanged by rRalGds
    *** cells: none
    *** source: 8094051(D)
  *** rRhob GTP-association[Mant-GTP] is unchanged by rArhGef4(271-632)"DH/PH"
    *** cells: none
    *** source: 17704816-Fig-S1
*** Rhob--
  *** rRhoc GTP-association[Mant-GTP] is unchanged by rArhGef4(271-632)"DH/PH"
    *** cells: none
    *** source: 17704816-Fig-S1
*** Rhoc--
  *** rRhog GTP-association[Mant-GTP] is unchanged by rArhGef4(271-632)"DH/PH"
    *** cells: none
    *** source: 17704816-Fig-S1
*** Rhog--
  *** xRhog(G12V)[tAb] infraction(membrane)[WB] is detectable
    *** cells: HEK293T<xDock1><xRhog(G12V)><xElmo2> in BMS
    *** unaffected by: xElmo2(1-618) [substitution]
    *** source: 12879077-Fig-S1a
  *** xRhog(G12V)[tAb] infraction(membrane)[WB] is detectable
    *** cells: HEK293T<xDock1><xRhog(G12V)><xElmo2> in BMS
    *** unaffected by: xRhog(G12V/F37A) [substitution]
    *** source: 12879077-Fig-S1a
  *** xRhog(G12V)[tAb] locatedin(cellmembrane)[IHC] is detectable
    *** cells: HELA<xDock1><xElmo2><xRhog(G12V)> in BMS
    *** source: 12879077-Fig-S1b
  *** xRhog(G12V)[tAb] snaggedby[WB] rPak1(mnr)"CRIB"[GST] is undetectable
    *** cells: HEK293T<xRhog(G12V)> in BMS
    *** source: 12879077-Fig-1b
  *** xRhog(G12V)[tAb] snaggedby[WB] rRtkn(mnr)"RBD"[GST] is undetectable
    *** cells: HEK293T<xRhog(G12V)> in BMS
    *** source: 12879077-Fig-1b
  *** rRhog{GTPgS}[Ab] boundby[WB] rPak1(mnr)"CRIB"[GST] is undetectable
    *** cells: none
    *** unaffected by: rRhog{GDP} [substitution]
    *** source: 12879077-Fig-1c
  *** rRhoj GTP-association[Mant-GTP] is unchanged by rArhGef4(271-632)"DH/PH"
    *** cells: none
    *** source: 17704816-Fig-S1
*** Rhoj--
  *** rRhoq GDP-dissociation[3H-GDP] is unchanged by xSos1[tAb]IP
    *** cells: none
    *** source: 11309621-Fig-4a
  *** rRhoq GDP-dissociation[Mant-GDP] is unchanged by rArhGef4(233-448)"DH"
    *** cells: none
    *** source: 17214551-Fig-2f
  *** rRhoq GTP-association[Mant-GTP] is unchanged by rArhGef4(271-632)"DH/PH"
    *** cells: none
    *** source: 17704816-Fig-S1
*** Rhoq--
*** Rictor--
  *** Rictor[Ab] copptby[WB] (xRagB(Q99L)"GTP"[tAb] + xRagC(Q120L)"GTP"[tAb]) is undetectable
    *** cells: HEK293T<xRagB(Q99L)><xRagC(Q120L)> in BMS
    *** source: 18497260-Fig-1c
  *** Rictor[Ab] copptby[WB] Atm[Ab] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15268862-Fig-1c
  *** Rictor[Ab] copptby[WB] EgfR[Ab] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15268862-Fig-1c
  *** Rictor[Ab] copptby[WB] Ilk[Ab] is detectable
    *** cells: HELA in BMS "Cytoskeletal-extracts"
    *** comment: Mtor is not detectable in these extracts
    *** source: 18339839-Fig-1b
  *** Rictor[Ab] copptby[WB] Ilk[Ab] is detectable
    *** cells: MDAMB231 in BMS
    *** source: 18339839-Fig-1b
  *** Rictor[Ab] copptby[WB] Ilk[Ab] is detectable
    *** cells: MDAMB231 in BMS "Cytoskeletal-extracts"
    *** source: 18339839-Fig-1b
  *** Rictor[Ab] copptby[WB] Mtor[Ab] is detectable
    *** cells: HEK293E in BMS
    *** comment: unaffected by washing ppt with high salt
    *** source: 19446321-Fig-1d
  *** Rictor[Ab] copptby[WB] Mtor[Ab] is detectable
    *** cells: HEK293T in BMS
    *** source: 15467718-Fig-1
  *** Rictor[Ab] copptby[WB] Protor1[Ab] is detectable
    *** cells: HEK293 in BMS
    *** comment: coppt is unaffected by detergent used in lysis
    *** source: 17461779-Fig-3b
  *** Rictor[Ab] copptby[WB] Protor1[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 17461779-Fig-3a
  *** Rictor[Ab] copptby[WB] Protor1[Ab] is detectable
    *** cells: HELA in BMS
    *** source: 17461779-Fig-4c
  *** Rictor[Ab] copptby[WB] Raptor[Ab] is undetectable
    *** cells: HEK293E in BMS
    *** comment: unaffected by washing ppt with high salt
    *** source: 19446321-Fig-1d
  *** Rictor[Ab] copptby[WB] Raptor[Ab] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15268862-Fig-2b
  *** Rictor[Ab] copptby[WB] Raptor[Ab] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15467718-Fig-1
  *** Rictor[Ab] copptby[WB] Raptor[Ab] is undetectable
    *** cells: HEK293T in BMS
    *** source: 17277771-Fig-1b
  *** Rictor[Ab] copptby[WB] Raptor[Ab] is undetectable
    *** cells: HEK293T in BMS
    *** source: 17510057-Fig-1b
  *** Rictor[Ab] copptby[WB] xFkbp12[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** unaffected by: Rapamycin [addition]
    *** source: 15268862-Fig-3b
  *** Rictor[Ab] copptby[WB] xIlk[tAb] is detectable
    *** cells: HEK293 in BMS "Cytoskeletal-extracts"
    *** source: 18339839-Fig-1a
  *** xRictor[Ab] copptby[WB] xProtor1[Ab] is detectable
    *** cells: HEK293<xMtor><xRictor><xSin1><xProtor1><xMlst8> in BMS
    *** does not req: xMtor [omission]
    *** does not req: xSin1 [omission]
    *** source: 17461779-Fig-4a
  *** Rictor[Ab] copptby[WB] xProtor1[tAb] is detectable
    *** cells: HEK293<xProtor1> in BMS
    *** unaffected by: xProtor1b [substitution]
    *** inhibited by: xProtor1g [substitution]
    *** source: 17461779-Fig-2d
  *** Rictor[Ab] copptby[WB] xProtor2[tAb] is detectable
    *** cells: HEK293<xProtor1> in BMS
    *** source: 17461779-Fig-2d
  *** xRictor[Ab] copptby[WB] xSin1[Ab] is detectable
    *** cells: HEK293<xMtor><xRictor><xSin1><xProtor1><xMlst8> in BMS
    *** does not req: xProtor1 [omission]
    *** source: 17461779-Fig-4a
  *** Rictor[Ab] infraction(P100)[WB] is detectable
    *** cells: HELA in BMLS
    *** source: 21464307-Fig-5c
  *** Rictor[Ab] infraction(P100)[WB] is detectable
    *** cells: HELA in BMS
    *** source: 21464307-Fig-5c
  *** Rictor[Ab] infraction(S100)[WB] is detectable
    *** cells: MDCK2 in BMS
    *** source: 21464307-Fig-5c
  *** Rictor[Ab]IP IVKA(Akt1)(S473)[phosAb] is detectable
    *** cells: HEK293T in BMS
    *** comment: Rictor IP contains Mtor but not Raptor
    *** source: 15718470-Fig-3a
  *** Rictor[Ab]IP IVKA(Akt1)(S473)[phosAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: LY294002 [addition]
    *** inhibited by: Wortmannin [addition]
    *** unaffected by: Staurosporine [addition]
    *** source: 15718470-Fig-3c
  *** Rictor[Ab]IP IVKA(Akt1)(S473)[phosAb] is detectable
    *** cells: HEK293T in BMS
    *** reqs: Mtor [RNAi]
    *** source: 15718470-Fig-3b
  *** Rictor[Ab]IP IVKA(Akt1)(S473)[phosAb] is detectable
    *** cells: HELA in BMS
    *** comment: Rictor IP contains Mtor but not Raptor
    *** source: 15718470-Fig-3a
  *** Rictor[Ab]IP IVKA(Akt1)(S473)[phosAb] is detectable
    *** cells: HELA in BMS
    *** reqs: Mtor [RNAi]
    *** reqs: Sin1 [RNAi]
    *** does not req: Raptor [RNAi]
    *** comment: Rictor IP contains Mtor and Sin1, not Raptor
    *** source: 17043309-Fig-4a
  *** Rictor[Ab]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: HEK293 in BMS
    *** comment: ref shows 32P-Mtor but they don't say how the know what it is
    *** comment: ref shows 32P-Eif4ebp1 but they don't say how the know what it is
    *** comment: unaffected by Rapamycin in kinase reaction
    *** source: 15467718-Fig-2b
  *** Rictor[Ab]IP phos[32Pi] is detectable
    *** cells: HELA in BMS
    *** partially reqs: Mtor [RNAi]
    *** source: 15268862-Fig-S1a
  *** Rictor[Ab]IP phos[WBMS-PPase] is detectable
    *** cells: HELA in BMS
    *** partially reqs: Mtor [RNAi]
    *** source: 15268862-Fig-S1a,S1b,S1c
  *** Rictor[MS] copptby[WB] xIlk[tAb] is detectable
    *** cells: HEK293 in BMS "Cytoskeletal-extracts"
    *** source: 18339839-Fig-1a
  *** xRictor[tAb] copptby[WB] (xRagA[tAb] + xRagB[tAb]) is undetectable
    *** cells: HEK293T<xRictor><xRagA><xRagB> in BMS
    *** source: 18497260-Fig-S1
  *** xRictor[tAb] copptby[WB] (xRagA[tAb] + xRagC[tAb]) is undetectable
    *** cells: HEK293T<xRictor><xRagA><xRagC> in BMS
    *** source: 18497260-Fig-S1
  *** xRictor[tAb] copptby[WB] (xRagB[tAb] + xRagC[tAb]) is undetectable
    *** cells: HEK293T<xRictor><xRagB><xRagC> in BMS
    *** source: 18497260-Fig-S1
  *** xRictor[tAb] copptby[WB] xRap2a[tAb] is undetectable
    *** cells: HEK293T<xRictor><xRap2a> in BMS
    *** source: 18497260-Fig-S1
*** Rig1--
  *** rRig1(mnr)"Nterm"[Ab] ubiq[K63UbAb] is increased by (rUbiq + pUbe1 + rUbc13 + rUev1a + rTrim25)
    *** cells: none
    *** partially inhibited by: rCyld [addition]
    *** partially inhibited by: rUsp5 [addition]
    *** inhibited by: rLprotein!9Viru(mnr)"OTU-domain" [addition]
    *** source: 19675569-Fig-S11b
  *** rRig1(mnr)"Nterm"[Ab] ubiq[K63UbAb] is increased by (rUbiq + pUbe1 + rUbc13 + rUev1a + rTrim25)
    *** cells: none
    *** reqs: rUbc13 and/or rUev1a [omission]
    *** source: 19675569-Fig-S11a
  *** rRig1(mnr)"Nterm"[Ab] upshift[WBMS] is increased by (rUbiq + pUbe1 + rUbc13 + rUev1a + rTrim25)
    *** cells: none
    *** reqs: rUbc13 and/or rUev1a [omission]
    *** source: 19675569-Fig-S11a
  *** rRig1(mnr)"Nterm"[Ab] upshift[WBMS] is increased by (rUbiq + pUbe1 + rUbc13 + rUev1a + rTrim25)
    *** cells: none
    *** unaffected by: rCyld [addition]
    *** unaffected by: rUsp5 [addition]
    *** inhibited by: rLprotein!9Viru(mnr)"OTU-domain" [addition]
    *** source: 19675569-Fig-S11b
  *** Rig1[Ab] copptby[WB] Azi2[Ab] is detectable
    *** cells: HELA in BMS "treated with Ifnb1 for 24 hr"
    *** source: 17142768-Fig-1b
  *** xRig1[tAb] copptby[WB] xAzi2(del(158-270))[tAb] is detectable
    *** cells: HEK293<xMda5><xAzi2(del(158-270))> in BMS
    *** source: 17142768-Fig-1d
  *** xRig1[tAb] copptby[WB] xAzi2[tAb] is detectable
    *** cells: HEK293<xMda5><xAzi2> in BMS
    *** source: 17142768-Fig-1a
  *** xRig1[tAb] copptby[WB] xHras[Ab] is detectable
    *** cells: HTTA in BMS
    *** inhibited by: xRig1(del(Cterm)) [substitution]
    *** source: 16005186-Fig-4b
  *** xRig1[tAb] copptby[WB] xMavs[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 16125763-Fig-S5a
  *** xRig1[tAb] copptby[WB] xMavs[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 16127453-Fig-5a
  *** xRig1[tAb] snaggedby[WB] c-diAMP[biotin] is undetectable
    *** cells: HEK293T<xRig1> in BMS
    *** source: 23142775-Fig-S3d
  *** xRig1[tAb] snaggedby[WB] ssRNA[biotin] is detectable
    *** cells: HEK293 in BMS
    *** comment: inhibited by RNase T1 treatment of ssRNA
    *** source: 17038590-Fig-4a
*** Rilp
  *** Rilp[Ab] colocwith[IHC] Ap1g1[Ab] is detectable
    *** cells: CACO2 in BMS
    *** source: 16882731(D)
  *** Rilp[Ab] colocwith[IHC] Lamp1[Ab] is detectable
    *** cells: CACO2 in BMS
    *** source: 16882731(D)
  *** Rilp[Ab] colocwith[IHC] TfRc[Ab] is detectable
    *** cells: CACO2 in BMS
    *** source: 16882731(D)
  *** Rilp[Ab] snaggedby[WB] rRab7a(Q67L)"CA"[GST] is detectable
    *** cells: HELA in BMS
    *** source: 16882731(D)
  *** Rilp[Ab] snaggedby[WB] rRab7a(T22N)"DN"[GST] is detectable
    *** cells: HELA in BMS
    *** source: 16882731(D)
*** Rin1--
  *** xRin1(294-783)"Cterm"[Ab] copptby[WB] xHras(Q61L)[Ab] is detectable
    *** cells: NIH3T3<xRin1(294-783)"Cterm"><xHras(Q61L)> in BMS
    *** source: 9144171-Fig-2b
  *** xRin1(Q78L)[tAb] copptby[WB] xRaf1[tAb] is detectable
    *** cells: COS<xRaf1><xHras(Q61L)> in BMS
    *** source: 16157584-Fig-5b
  *** rRin1[Ab] boundby[WB] Hras{GDP}[GST] is undetectable
    *** cells: none
    *** source: 11784866-Fig-1a
  *** rRin1[Ab] boundby[WB] Hras{GTPgS}[GST] is detectable
    *** cells: none
    *** source: 11784866-Fig-1a
  *** Rin1[Ab] copptby[WB] Abl1[Ab] is detectable
    *** cells: MCF10A in BMS
    *** source: 15886098-Fig-2b
  *** xRin1[Ab] copptby[WB] xAbl1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15886098-Fig-2b
  *** xRin1[Ab] copptby[WB] xAbl2[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15886098-Fig-2a
  *** xRin1[Ab] copptby[WB] xAbl2[tAb] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xAbl2(Y439S) [substitution]
    *** inhibited by: xAbl2(K319R) [substitution]
    *** comment: coppt xRin1 is phosed on Y36 [phosAb]
    *** source: 15886098-Fig-2c
  *** xRin1[Ab] copptby[WB] xAbl2[tAb] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xHras(G12V) [addition]
    *** source: 15886098-Fig-6a
  *** xRin1[Ab] copptby[WB] xHras(Q61L)[Ab] is detectable
    *** cells: NIH3T3<xRin1><xHras(Q61L)> in BMS
    *** source: 9144171-Fig-2a
  *** xRin1[Ab]IP phos(Y36)[phosAb] is increased itpo xAbl2
    *** cells: HEK293T in BMS
    *** source: 15886098-Fig-3b
  *** xRin1[Ab]IP Yphos[pYAb] is detectable
    *** cells: mEFs in BMS
    *** does not req: Abl1 [KO]
    *** does not req: Abl2 [KO]
    *** reqs: Abl1 and/or Abl2 [DKO]
    *** source: 15886098-Fig-3a
  *** rRin1[His] phos[32P-ATP] is increased by Abl1[Ab]IP
    *** cells: none
    *** IPfrom: SF9 in BMS
    *** source: 9144171-Fig-7
  *** xRin1[tAb] copptby[WB] xHras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xHras(G12V/D38A) [substitution]
    *** inhibited by: xHras(G12V/T35S) [substitution]
    *** unaffected by: xHras(G12V/E37G) [substitution]
    *** inhibited by: xHras(G12V/Y40C) [substitution]
    *** unaffected by: xHras(G12V/D38E) [substitution]
    *** source: 15143186-Fig-6
  *** xRin1[tAb] copptby[WB] xKras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRin1[tAb] copptby[WB] xMras(Q71L)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRin1[tAb] copptby[WB] xNras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRin1[tAb] copptby[WB] xRap1a(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRin1[tAb] copptby[WB] xRap2a(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRin1[tAb] copptby[WB] xRras(G38V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRin1[tAb] copptby[WB] xRras2(G23V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
*** Rin2--
  *** xRin2[tAb] copptby[WB] xHras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xHras(G12V/D38A) [substitution]
    *** inhibited by: xHras(G12V/T35S) [substitution]
    *** unaffected by: xHras(G12V/E37G) [substitution]
    *** inhibited by: xHras(G12V/Y40C) [substitution]
    *** inhibited by: xHras(G12V/D38E) [substitution]
    *** source: 15143186-Fig-6
  *** xRin2[tAb] copptby[WB] xKras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRin2[tAb] copptby[WB] xMras(Q71L)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRin2[tAb] copptby[WB] xNras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRin2[tAb] copptby[WB] xRap1a(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRin2[tAb] copptby[WB] xRap2a(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRin2[tAb] copptby[WB] xRras(G38V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRin2[tAb] copptby[WB] xRras2(G23V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
*** Rin3--
  *** xRin3[tAb] copptby[WB] xHras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xHras(G12V/D38A) [substitution]
    *** inhibited by: xHras(G12V/T35S) [substitution]
    *** inhibited by: xHras(G12V/E37G) [substitution]
    *** inhibited by: xHras(G12V/Y40C) [substitution]
    *** inhibited by: xHras(G12V/D38E) [substitution]
    *** source: 15143186-Fig-6
  *** xRin3[tAb] copptby[WB] xKras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRin3[tAb] copptby[WB] xMras(Q71L)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRin3[tAb] copptby[WB] xNras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRin3[tAb] copptby[WB] xRap1a(G12V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRin3[tAb] copptby[WB] xRap2a(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRin3[tAb] copptby[WB] xRras(G38V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
  *** xRin3[tAb] copptby[WB] xRras2(G23V)"CA"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15143186-Fig-5
*** Ripk1--
  *** xRipk1(K45A)[tAb]IP phos[32P-ATP] is increased by rCsnk1a1
    *** cells: none
    *** source: 18067272-Fig-4a
  *** xRipk1(K45A)[tAb]IP STphos[pSTAb] is increased itpo xCsnk1a1
    *** cells: HEK293T in BMS
    *** inhibited by: xCsnk1a1(K46A)"KD" [substitution]
    *** inhibited by: IC261 [addition]
    *** source: 18067272-Fig-4b
  *** xRipk1[Ab]IP ubiq[tUbAb] is increased itpo xPeli1
    *** cells: HEK293<xRipk1><xUbiq> in BMS
    *** enhanced by: xTrif [addition]
    *** source: 19734906-Fig-6d
  *** xRipk1[Ab]IP ubiq[tUbAb] is increased itpo xPeli1
    *** cells: HEK293<xRipk1><xUbiq> in BMS
    *** inhibited by: xPeli1(mnr)"delRing" [substitution]
    *** inhibited by: xPeli1(mnr)"PointSubstitutions" [substitution]
    *** source: 19734906-Fig-6d
  *** xRipk1[Ab]IP ubiq[WBMS] is increased itpo xPeli1
    *** cells: HEK293<xRipk1><xUbiq> in BMS
    *** source: 19734906-Fig-6e
  *** xRipk1[tAb] copptby[WB] xSqstm1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: xTraf6 [addition]
    *** source: 10747026-Fig-10
*** Ripk2--
  *** xRipk2[Ab] copptby[WB] xCasp1[Ab] is detectable
    *** cells: HEK293<xIL1b> in BMS
    *** comment: inhibited by very high concentrations of xPycard [addition]
    *** source: 16585594-Fig-4a
  *** xRipk2[tAb] copptby[WB] xCasp1(C285A)[tAb] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xIceberg [addition]
    *** source: 11051551(D)
  *** xRipk2[tAb] copptby[WB] xNod1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 10329646(D)
  *** xRipk2[tAb] copptby[WB] xNod2[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 11087742-Fig-6a
  *** xRipk2[tAb] phos[WBMS] is increased itpo xNod2
    *** cells: HEK293T in BMS
    *** source: 11087742-Fig-6a
  *** xRipk2[tAb] snaggedby[WB] rIceberg[GST] is undetectable
    *** cells: HEK293 in BMS
    *** source: 11051551(D)
  *** rRit1 GDP-dissociation[3H-GDP] is unchanged by rPlce1
    *** cells: none
    *** source: 11395506-Fig-3
*** Rit1--
  *** rRit2 GDP-dissociation[3H-GDP] is unchanged by rPlce1
    *** cells: none
    *** source: 11395506-Fig-3
*** Rit2--
*** Rnf8--
  *** xRnf8(R61Q)[tAb] locatedin(subnuclear-bodies)[IHC] is unchanged irt IR (6 hr)
    *** cells: NotReported<xRnf8> in BMS
    *** comment: colocates with H2ax{phos(S140)}[phosAb]
    *** source: 18001825-Fig-S2c
  *** Rnf8[Ab] snaggedby[WB] sMdc1(709-724){phos(T719)}[biotin] is detectable
    *** cells: HELA in BMS
    *** inhibited by: sMdc1(709-724)"T719" [substitution]
    *** source: 18006705-Fig-3b
  *** Rnf8[Ab] snaggedby[WB] sMdc1(743-757){phos(T752)}[biotin] is detectable
    *** cells: HELA in BMS
    *** inhibited by: sMdc1(743-757)"T752" [substitution]
    *** source: 18006705-Fig-3b
  *** xRnf8[tAb] copptby[WB] xMdc1(1-1100)[tAb] is detectable
    *** cells: HEK293T<xRnf8><xMdc1(1-1100)> in BMS
    *** inhibited by: xMdc1(1-1100/T699A/T719A/T752A) [substitution]
    *** source: 18001824-Fig-2d
  *** xRnf8[tAb] copptby[WB] xMdc1(1-1100)[tAb] is detectable
    *** cells: HEK293T<xRnf8><xMdc1(1-1100)> in BMS
    *** inhibited by: xRnf8(R42A)"mutFHA" [substitution]
    *** unaffected by: xRnf8(C403S)"mutRING" [substitution]
    *** source: 18001824-Fig-2b
  *** xRnf8[tAb] copptby[WB] xMdc1[SBP] is detectable
    *** cells: HEK293T<xMdc1><xRnf8> in BMS
    *** inhibited by: xMdc1(del(698-768)) [substitution]
    *** source: 18001825-Fig-3d
  *** xRnf8[tAb] copptby[WB] xMdc1[SBP] is detectable
    *** cells: HEK293T<xMdc1><xRnf8> in BMS
    *** inhibited by: xRnf8(mnr)"delFHA" [substitution]
    *** source: 18001825-Fig-3e
  *** xRnf8[tAb] copptby[WB] xMdc1[tAb] is detectable
    *** cells: HEK293T<xRnf8><xMdc1> in BMS
    *** unaffected by: xMdc1(1-1100) [substitution]
    *** unaffected by: xMdc1(1-800) [substitution]
    *** inhibited by: xMdc1(1-600) [substitution]
    *** inhibited by: xMdc1(1-500) [substitution]
    *** source: 18001824-Fig-S2a
  *** xRnf8[tAb] snaggedby[WB] rH2ax(mnr){phos}[SBP] is detectable
    *** cells: HEK293T<xRnf8> in BMS
    *** inhibited by: rH2ax(mnr) [substitution]
    *** source: 18001825-Fig-S2d
  *** xRnf8[tAb] snaggedby[WB] rH2ax(mnr){phos}[SBP] is detectable
    *** cells: HEK293T<xRnf8> in BMS
    *** inhibited by: xRnf8(mnr)"delFHA" [substitution]
    *** inhibited by: xRnf8(mnr)"delRING" [substitution]
    *** source: 18001825-Fig-S2d
  *** xRnf8[tAb] snaggedby[WB] rH2ax(mnr){phos}[SBP] is detectable
    *** cells: HEK293T<xRnf8> in BMS
    *** source: 18001825-Fig-S2e
*** Rock1--
  *** xRock1[Ab] snaggedby[WB] rHras{GTPgS}[GST] is undetectable
    *** cells: COS7 in BMS
    *** unaffected by: rHras{GDP} [substitution]
    *** source: 12900402-Fig-5
  *** xRock1[Ab] snaggedby[WB] rRac1{GTPgS}[GST] is undetectable
    *** cells: COS7 in BMS
    *** unaffected by: rRac1{GDP} [substitution]
    *** source: 12900402-Fig-5
*** Rock2--
  *** Rock2[MS] copptby[WB] xStau1[tAb] is detectable
    *** cells: HEK293T in BMS "infected with vaccinia vTf7-3 virus"
    *** source: 15121898(D)
  *** xRor2[Ab] copptby[WB] xDvl2[tAb] is increased itpo xCsnk1e
    *** cells: COS1<xRor2> in BMS
    *** unaffected by: xRor2(mnr)"13ST" [substitution]
    *** source: 20215527-Fig-3c
  *** xRor2[tAb] copptby[WB] xDvl3[tAb] is increased itpo xCsnk1e
    *** cells: COS7<xDvl3><xRor2> in BMS
    *** source: 20215527-Fig-1c
  *** RoRa-gene mRNA[RTPCR] is detectable
    *** cells: hMemoryCD4TCs<CcR4~neg><CcR6~pos> in BMS
    *** source: 18454151-Fig-S6b
  *** RoRa-gene mRNA[RTPCR] is detectable
    *** cells: hMemoryCD4TCs<CcR4~neg><CcR6~pos> in BMS
    *** source: 18454151-Fig-S6b
  *** RoRa-gene mRNA[RTPCR] is undetectable
    *** cells: hMemoryCD4TCs<CcR4~neg><CcR6~neg> in BMS
    *** source: 18454151-Fig-S6b
  *** RoRa-gene mRNA[RTPCR] is undetectable
    *** cells: hMemoryCD4TCs<CcR4~pos><CcR6~neg> in BMS
    *** source: 18454151-Fig-S6b
  *** RoRc-gene mRNA[RTPCR] is detectable
    *** cells: hMemoryCD4TCs<CcR4~neg><CcR6~pos> in BMS
    *** source: 18454151-Fig-2b
  *** RoRc-gene mRNA[RTPCR] is detectable
    *** cells: hMemoryCD4TCs<CcR4~neg><CcR6~pos> in BMS
    *** source: 18454151-Fig-2b
  *** RoRc-gene mRNA[RTPCR] is undetectable
    *** cells: hMemoryCD4TCs<CcR4~neg><CcR6~neg> in BMS
    *** source: 18454151-Fig-2b
  *** RoRc-gene mRNA[RTPCR] is undetectable
    *** cells: hMemoryCD4TCs<CcR4~pos><CcR6~neg> in BMS
    *** source: 18454151-Fig-2b
  *** xRoRc[Ab] copptby[WB] xFoxp3[tAb] is detectable
    *** cells: HEK293T<xRoRc><xFoxp3> in BMS
    *** inhibited by: xFoxp3(mnr)"exon2-deleted" [substitution]
    *** source: 18368049-Fig-3a
*** Rpl6--
  *** Rpl6[MS] copptby[WB] xStau1[tAb] is detectable
    *** cells: HEK293T in BMS "infected with vaccinia vTf7-3 virus"
    *** source: 15121898(D)
  *** Rpl13a-gene mRNA[RTPCR] is detectable-but unchanged itpo xMek1(S218D/S222D)
    *** cells: AKR2B in BMLS
    *** source: 23913859-Fig-3d
*** Rpl28--
  *** Rpl28[Ab] colocwith[IHC] Stau1[Ab] is detectable
    *** cells: SHSY5Y in BMS "differentiated with retinoic acid for 7 days"
    *** source: 15121898(D)
  *** Rpl28[Ab] copptby[WB] xStau1[tAb] is detectable
    *** cells: HEK293T in BMS "infected with vaccinia vTf7-3 virus"
    *** source: 15121898(D)
  *** Rpl28[MS] copptby[WB] xStau1[tAb] is detectable
    *** cells: HEK293T in BMS "infected with vaccinia vTf7-3 virus"
    *** source: 15121898(D)
*** Rplp0--
  *** Rplp0[MS] copptby[WB] xStau1[tAb] is detectable
    *** cells: HEK293T in BMS "infected with vaccinia vTf7-3 virus"
    *** source: 15121898(D)
*** Rps6--
  *** Rps6[Ab] copptby[WB] Eif3b[Ab] is detectable
    *** cells: HEK293E<xS6k1> in BMLS
    *** unaffected by: xS6k1(T412A) [substitution]
    *** source: 16286006-Fig-4c
  *** Rps6[phosAb] phos(S235)[phosAb] is detectable
    *** cells: mESCs in BMLS
    *** reqs: Pdpk1 [KO]
    *** source: 11500364-Fig-S1a
  *** Rps6[phosAb] phos(S235)[phosAb] is increased itao Tsc2 [KO]
    *** cells: mEFs in BMLS
    *** source: 15024086-Fig-5b
  *** Rps6[phosAb] phos(S235/S236)[phosAb] is decreased irt U0126 (4 hr)
    *** cells: A375 in BMLS "Low-Glucose"
    *** source: 19274086-Fig-3a
  *** Rps6[phosAb] phos(S235/S236)[phosAb] is decreased irt U0126 (4 hr)
    *** cells: SKMEL28 in BMLS "Low-Glucose"
    *** source: 19274086-Fig-3a
  *** Rps6[phosAb] phos(S235/S236)[phosAb] is decreased itpo (xTsc1 + xTsc2)
    *** cells: HEK293T in BMLS
    *** source: 12842888-Fig-4a
  *** Rps6[phosAb] phos(S235/S236)[phosAb] is decreased itpo xDdit4
    *** cells: U2OS in BMS
    *** unaffected by: xDdit4(del(96-156))"dC" [substitution]
    *** source: 15988001-Fig-5a
  *** Rps6[phosAb] phos(S235/S236)[phosAb] is detectable
    *** cells: HEK293 in BMLS
    *** partially reqs: Rheb [RNAi]
    *** source: 16803888-Fig-1e
  *** Rps6[phosAb] phos(S235/S236)[phosAb] is detectable
    *** cells: HEK293<xSgk1> in BMS
    *** inhibited by: PI103 [pretreatment]
    *** inhibited by: Rapamycin [pretreatment]
    *** source: 18925875-Fig-5a
  *** Rps6[phosAb] phos(S235/S236)[phosAb] is detectable
    *** cells: mESCs in BMLS
    *** inhibited by: kPdpk1(L155E)"PIF" [knockin]
    *** source: 16763566-Fig-3b
  *** Rps6[phosAb] phos(S235/S236)[phosAb] is detectable
    *** cells: mESCs in BMLS
    *** reqs: Pdpk1 [KO]
    *** source: 16763566-Fig-3a
  *** Rps6[phosAb] phos(S235/S236)[phosAb] is increased itao Tsc2 [KO]
    *** cells: mEFs in BMLS
    *** source: 16027121-Fig-6a
  *** Rps6[phosAb] phos(S235/S236)[phosAb] is increased itao Tsc2 [KO]
    *** cells: mEFs in BMS
    *** source: 15545625-Fig-1b
  *** Rps6[phosAb] phos(S235/S236)[phosAb] is increased itao Tsc2 [KO]
    *** cells: mEFs<Tp53~null> in BMLS
    *** inhibited by: Rapamycin [pretreatment]
    *** source: 15545625-Fig-1a
  *** Rps6[phosAb] phos(S235/S236)[phosAb] is increased itao Tsc2 [KO]
    *** cells: mEFs<Tp53~null> in BMLS
    *** unaffected by: Serum (45 min) [stim]
    *** source: 15545625-Fig-1a
  *** Rps6[phosAb] phos(S235/S236)[phosAb] is increased itao Tsc2 [RNAi]
    *** cells: HEK293 in BMLS
    *** source: 16803888-Fig-3a
  *** Rps6[phosAb] phos(S235/S236)[phosAb] is increased itao Tsc2 [RNAi]
    *** cells: HELA in BMS "Serum- and AminoAcid-deprived, treated with (EAA + Glutamine) for 60 min"
    *** source: 19203585-Fig-5a
  *** Rps6[phosAb] phos(S235/S236)[phosAb] is increased itao Tsc2 [RNAi]
    *** cells: HELA in BMS "Serum- and AminoAcid-deprived"
    *** source: 19203585-Fig-5a
  *** Rps6[phosAb] phos(S235/S236)[phosAb] is increased itpo xGnai3(Q204L)"CA"
    *** cells: mEFs<Gnai1~null><Gnai3~null> in BMLS
    *** source: 19401591-Fig-3d
  *** Rps6[phosAb] phos(S235/S236)[phosAb] is increased itpo xHras(Q61L)"CA"
    *** cells: HEK293E in BMLS
    *** inhibited by: xHras(S17N)"DN" [substitution]
    *** source: 17360704-Fig-2b
  *** Rps6[phosAb] phos(S235/S236)[phosAb] is increased itpo xHras(Q61L)"CA"
    *** cells: HEK293E in BMLS
    *** partially inhibited by: U0126 [pretreatment]
    *** source: 17360704-Fig-2c
  *** Rps6[phosAb] phos(S235/S236)[phosAb] is increased itpo xMek1(S218D/S222D)"CA"
    *** cells: HEK293E in BMLS
    *** source: 17360704-Fig-2b
  *** Rps6[phosAb] phos(S235/S236)[phosAb] is increased itpo xRheb
    *** cells: HEK293T in BMLS
    *** bkg inhibited by: FTI277 [addition]
    *** source: 12842888-Fig-6b
  *** Rps6[phosAb] phos(S235/S236)[phosAb] is increased itpo xRheb
    *** cells: HEK293T in BMLS
    *** bkg inhibited by: Rapamycin [addition]
    *** unaffected by: U0126 [addition]
    *** source: 12842888-Fig-6a
  *** Rps6[phosAb] phos(S235/S236)[phosAb] is increased itpo xRheb
    *** cells: HEK293T in BMLS
    *** partially inhibited by: xRheb(Q64L) [substitution]
    *** source: 12842888-Fig-4b
  *** Rps6[phosAb] phos(S235/S236)[phosAb] is increased itpo xRheb
    *** cells: HEK293T in BMLS
    *** source: 12842888-Fig-5
  *** Rps6[phosAb] phos(S235/S236)[phosAb] is unchanged irt Glucose-deprivation (4 hr)
    *** cells: A375 in BMLS
    *** source: 19274086-Fig-3a
  *** Rps6[phosAb] phos(S235/S236)[phosAb] is unchanged itpo xAkt1(myr)"CA"
    *** cells: mEFs<Tsc2~null><xTsc2(S939D/S1086D/S1088E/T1422E)> in BMS
    *** source: 16027121-Fig-7b
  *** Rps6[phosAb] phos(S235/S236)[phosAb] is unchanged itpo xAkt1(myr)"CA"
    *** cells: RAT1A in BMS
    *** source: 16027121-Fig-4a
  *** Rps6[phosAb] phos(S235/S236)[phosAb] is unchanged itpo xRap1a(F64A)"CA"
    *** cells: HEK293T in BMLS
    *** source: 12842888-Fig-4b
  *** Rps6[phosAb] phos(S235/S236)[phosAb] is unchanged itpo xRap1a(Q63E)"CA"
    *** cells: HEK293T in BMLS
    *** source: 12842888-Fig-4b
  *** Rps6[phosAb] phos(S235/S236)[phosAb] is undetectable
    *** cells: 3731E in BMLS "Low-Glucose"
    *** unaffected by: U0126 [addition]
    *** source: 19274086-Fig-3a
  *** Rps6[phosAb] phos(S240/S244)[phosAb] is decreased itpo xApc
    *** cells: HT29<Apc~null> in BMLS
    *** source: 16959574-Fig-S4d
  *** Rps6[phosAb] phos(S240/S244)[phosAb] is detectable
    *** cells: mEFs in BMLS
    *** reqs: Ctnnb1 [KO]
    *** source: 16959574-Fig-4h
  *** Rps6[phosAb] phos(S240/S244)[phosAb] is increased itao Tsc2 [RNAi]
    *** cells: HEK293 in BMS
    *** source: 12172553-Fig-2b
  *** Rps6[phosAb] phos(S240/S244)[phosAb] is increased itpo xHras(Q61L)"CA"
    *** cells: HEK293E in BMLS
    *** inhibited by: xHras(S17N)"DN" [substitution]
    *** source: 17360704-Fig-2b
  *** Rps6[phosAb] phos(S240/S244)[phosAb] is increased itpo xHras(Q61L)"CA"
    *** cells: HEK293E in BMLS
    *** unaffected by: U0126 [pretreatment]
    *** source: 17360704-Fig-2c
  *** Rps6[phosAb] phos(S240/S244)[phosAb] is increased itpo xMek1(S218D/S222D)"CA"
    *** cells: HEK293E in BMLS
    *** source: 17360704-Fig-2b
  *** Rps6[phosAb] phos(sitenr)[phosAb] is detectable
    *** cells: HEK293T<xMtor><xRheb> in BMLS
    *** inhibited by: AA-deprivation (1 hr) [stim]
    *** inhibited by: H2O2 (30 min) [stim]
    *** inhibited by: Sorbitol (30 min) [stim]
    *** unaffected by: Arsenite (30 min) [stim]
    *** source: 15772076-Fig-6a
  *** Rps6[phosAb] phos(sitenr)[phosAb] is detectable
    *** cells: mESCs in BMLS
    *** reqs: Pdpk1 [KO]
    *** inhibited by: kPdpk1(L155E) [substitution]
    *** source: 12912918-Fig-4a
  *** Rps6[phosAb] phos(sitenr)[phosAb] is increased itao Tsc2 [KO]
    *** cells: mEFs in BMLS
    *** inhibited by: AA-deprivation [addition]
    *** unaffected by: AA-deprivation + CHX [addition]
    *** inhibited by: Rapamycin [addition]
    *** source: 15772076-Fig-4a
  *** Rps6[phosAb] phos(sitenr)[phosAb] is increased itao Tsc2 [KO]
    *** cells: mEFs in BMLS
    *** source: 15772076-Fig-2a
  *** Rps6[phosAb] phos(sitenr)[phosAb] is increased itao Tsc2 [KO]
    *** cells: mEFs in BMLS
    *** source: 15772076-Fig-3a
  *** Rps6[phosAb] phos(sitenr)[phosAb] is undetectable
    *** cells: mEFs in BMLS
    *** unaffected by: AA-deprivation [addition]
    *** unaffected by: AA-deprivation + CHX [addition]
    *** source: 15772076-Fig-4a
  *** xRps6[tAb] snaggedby[WB] capped-mRNA[m7GTP] is detectable
    *** cells: HEK293E<xRps6> in BMLS
    *** inhibited by: xRps6(S235A/S236A) [substitution]
    *** enhanced by: xRps6(S235D/S236D) [substitution]
    *** source: 17360704-Fig-6c
  *** rRras GDP-dissociation[3H-GDP] is increased by rRasGrf2(mnr)"CatDom"
    *** cells: none
    *** source: 11500499-Fig-2
  *** rRras GDP-dissociation[3H-GDP] is unchanged by rPlce1
    *** cells: none
    *** source: 11395506-Fig-3
  *** rRras GDP-dissociation[3H-GDP] is unchanged by rRalGds
    *** cells: none
    *** source: 8094051-Fig-5
  *** rRras GDP-dissociation[3H-GDP] is unchanged by rRapGef3
    *** cells: none
    *** source: 10777492-Fig-2
  *** rRras GDP-dissociation[Mant-GDP] is unchanged by rRasGef1a
    *** cells: none
    *** source: 19645719-Fig-1c
  *** rRras GDP-dissociation[Mant-GDP] is unchanged by rRasGef1b
    *** cells: none
    *** source: 19645719-Fig-1c
*** Rras--
  *** xRras(L219S)[GST]IP GTP-association[TLC] is increased itpo xRasGrf2
    *** cells: COS7 in BMS
    *** source: 11500499-Fig-4
  *** xRras(mnr)"SAAX"[GST]IP GDP-dissociation[3H-GDP] is increased by rRasGrf2(mnr)"CatDom"
    *** cells: none
    *** IPfrom: COS7 in BMS
    *** inhibited by: xRras(WT)[GST]IP [substitution]
    *** source: 11500499-Fig-5a
  *** xRras(mnr)"SAAX"[GST]IP GTP-association[TLC] is increased itpo xRasGrf2
    *** cells: COS7 in BMS
    *** source: 11500499-Fig-3
  *** xRras[Ab] copptby[WB] xSh2d3c[Ab] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: xSh2d3c(Y635E) [substitution]
    *** unaffected by: xSh2d3c(Y635F) [substitution]
    *** source: 15272013-Fig-4b
  *** xRras[GST]IP GTP-association[TLC] is unchanged itpo xRalGps1
    *** cells: HEK293T in BMS
    *** source: 10777492-Fig-1a
  *** xRras[GST]IP GTP-association[TLC] is unchanged itpo xRapGef2
    *** cells: HEK293T in BMS
    *** source: 10777492-Fig-1a
  *** xRras[GST]IP GTP-association[TLC] is unchanged itpo xRapGef3
    *** cells: HEK293T in BMS
    *** source: 9856955-Fig-2a
  *** xRras[GST]IP GTP-association[TLC] is unchanged itpo xRapGef3
    *** cells: HEK293T in BMS
    *** unaffected by: cAMP [addition]
    *** source: 10777492-Fig-1a
  *** xRras[GST]IP GTP-association[TLC] is unchanged itpo xRapGef4
    *** cells: HEK293T in BMS
    *** source: 9856955-Fig-2a
  *** xRras[GST]IP GTP-association[TLC] is unchanged itpo xRapGef5
    *** cells: HEK293T in BMS
    *** source: 10777492-Fig-1a
  *** xRras[GST]IP GTP-association[TLC] is unchanged itpo xRasGrf2
    *** cells: COS7 in BMS
    *** source: 11500499-Fig-1b
  *** xRras[GST]IP GTP-association[TLC] is unchanged itpo xRasGrf2
    *** cells: COS7 in BMS
    *** source: 11500499-Fig-6c
  *** xRras[GST]IP GTP-association[TLC] is unchanged itpo xRasGrf2
    *** cells: COS7 in BMS
    *** source: 11500499-Fig-7b
  *** xRras[GST]IP GTP-association[TLC] is unchanged itpo xRasGrf2
    *** cells: COS7 in BMS
    *** source: 11500499-Fig-9
  *** xRras[GST]IP GTP-association[TLC] is unchanged itpo xRasGrf2
    *** cells: COS7 in BMS
    *** unaffected by: Ionomycin [addition]
    *** source: 11500499-Fig-1c
  *** xRras[GST]IP GTP-association[TLC] is unchanged itpo xSos1
    *** cells: HEK293 in BMS
    *** source: 11560935-Fig-1a
  *** xRras[GST]IP GTP-association[TLC] is unchanged itpo xSos1
    *** cells: HEK293T in BMS
    *** source: 9856955-Fig-2a
  *** xRras[GST]IP GTP-association[TLC] is unchanged itpo xSos1
    *** cells: HEK293T in BMS
    *** source: 10777492-Fig-1a
  *** xRras[tAb] GTP-association[BDPD] is unchanged itpo xRapGef2
    *** cells: COS7 in BMS
    *** source: 10608883-Fig-3b
  *** xRras[tAb] GTP-association[BDPD] is unchanged itpo xSh2d3c
    *** cells: HEK293T in BMS
    *** source: 12432078-Fig-2c
  *** xRras[tAb]IP GTP-association[TLC] is increased itpo xBcar3
    *** cells: HEK293 in BMS
    *** source: 10896938-Fig-1b
  *** rRras2 GDP-dissociation[3H-GDP] is unchanged by rRapGef3
    *** cells: none
    *** source: 10777492-Fig-2
  *** rRras2 GDP-dissociation[Mant-GDP] is unchanged by rRasGef1a
    *** cells: none
    *** source: 19645719-Fig-1c
  *** rRras2 GDP-dissociation[Mant-GDP] is unchanged by rRasGef1b
    *** cells: none
    *** source: 19645719-Fig-1c
*** Rras2--
  *** xRras2[GST]IP GTP-association[TLC] is unchanged itpo xRalGps1
    *** cells: HEK293T in BMS
    *** source: 10777492-Fig-1a
  *** xRras2[GST]IP GTP-association[TLC] is unchanged itpo xRapGef2
    *** cells: HEK293T in BMS
    *** source: 10777492-Fig-1a
  *** xRras2[GST]IP GTP-association[TLC] is unchanged itpo xRapGef3
    *** cells: HEK293T in BMS
    *** unaffected by: cAMP [addition]
    *** source: 10777492-Fig-1a
  *** xRras2[GST]IP GTP-association[TLC] is unchanged itpo xRapGef5
    *** cells: HEK293T in BMS
    *** source: 10777492-Fig-1a
  *** xRras2[GST]IP GTP-association[TLC] is unchanged itpo xSos1
    *** cells: HEK293T in BMS
    *** source: 10777492-Fig-1a
*** Rrm2b--
  *** Rrm2b[Ab] prot-exp[WB] is increased itpo xTp53
    *** cells: H1299<Tp53~null> in BMS
    *** unaffected by: xTp53(S46A) [substitution]
    *** unaffected by: xTp53(del(46-46)) [substitution]
    *** unaffected by: xTp53(S121F) [substitution]
    *** source: 11030628-Fig-8a
*** Rsk1--
  *** rRsk1((368-735)/K447R/S380A/T573A) phos[32P-ATP] is increased by xRsk1[tAb]IP
    *** cells: none
    *** IPfrom: HEK293<xRsk1> in BMLS "treated with Egf for 10 min"
    *** inhibited by: rRsk1((368-735)/K447R/S380A/T573A/S732A) [substitution]
    *** source: 12832467-Fig-4b
  *** rRsk1((368-735)/K447R/S380A/T573A) phos[32P-ATP] is increased by xRsk1[tAb]IP
    *** cells: none
    *** IPfrom: HEK293<xRsk1> in BMLS "treated with Egf for 10 min"
    *** inhibited by: xRsk1(K94R) [substitution]
    *** partially inhibited by: xRsk1(K447R) [substitution]
    *** inhibited by: xRsk1(K94R/K447R) [substitution]
    *** source: 12832467-Fig-4a
  *** Rsk1[Ab] prot-exp[WB] is detectable
    *** cells: mESCs in BMS
    *** does not req: Pdpk1 [KO]
    *** source: 11078882-Fig-1
  *** Rsk1[Ab]IP IVKA(Rela)[32P-ATP] is increased itpo xTp53
    *** cells: SAOS2 in BMS
    *** source: 15073170-Fig-5a
  *** xRsk1[GST]IP IVKA(Crosstide)[32P-ATP] is unchanged by rJnk1{act}
    *** cells: HEK293<xRsk1> in BMLS
    *** source: 9687510-Fig-3c
  *** xRsk1[GST]IP IVKA(Crosstide)[32P-ATP] is unchanged by rP38a{act}
    *** cells: HEK293<xRsk1> in BMLS
    *** source: 9687510-Fig-3c
  *** xRsk1[GST]IP IVKA(Crosstide)[32P-ATP] is unchanged by rP38b{act}
    *** cells: HEK293<xRsk1> in BMLS
    *** source: 9687510-Fig-3c
  *** xRsk1[GST]IP IVKA(Crosstide)[32P-ATP] is unchanged by rP38d{act}
    *** cells: HEK293<xRsk1> in BMLS
    *** source: 9687510-Fig-3c
  *** xRsk1[GST]IP IVKA(Crosstide)[32P-ATP] is unchanged by rP38g{act}
    *** cells: HEK293<xRsk1> in BMLS
    *** source: 9687510-Fig-3c
  *** Rsk1[phosAb] phos(T359/S363)[phosAb] is detectable
    *** cells: HEPG2 in BMLS "plated on collagen"
    *** partially inhibited by: Gefitinib [cotreatment]
    *** inhibited by: PD325901 [cotreatment]
    *** unaffected by: BMS345541 [cotreatment]
    *** unaffected by: PHA818637 [cotreatment]
    *** unaffected by: ZSTK474 [cotreatment]
    *** source: 19953085-Fig-S1
  *** xRsk1[tAb]IP IVKA(peptide)[32P-ATP] is increased by rErk1
    *** cells: COS7<xRsk1> in BMLS
    *** source: 8939914-Fig-6
  *** xRsk1[tAb]IP IVKA(peptide)[32P-ATP] is increased itpo xMek1(S218E/S222E)
    *** cells: COS7<xRsk1> in BMLS
    *** inhibited by: xMek1(S218A) [substitution]
    *** source: 8939914-Fig-2
  *** xRsk1[tAb]IP IVKA(Rps6)[32P-ATP] is increased itpo xPdpk1(51-556)
    *** cells: COS7<xRsk1> in BMLS
    *** source: 10480933-Fig-5
  *** xRsk1[tAb]IP IVKA(Rps6)[32P-ATP] is unchanged itpo xRheb
    *** cells: HEK293E<xRsk1> in BMLS
    *** source: 12906785-Fig-1c
*** Rsk2--
  *** xRsk2(373-740)"CTD"[phosAb] phos(S386)[phosAb] is increased itpo (xErk2 + xMek1(mnr)"CA")
    *** cells: Ecoli<xRsk2(373-740)> in BMS
    *** inhibited by: xRsk2(373-740/K451A) [substitution]
    *** source: 12016217-Fig-2a
  *** xRsk2(373-740)"CTD"[phosAb] phos(T577)[phosAb] is increased itpo (xErk2 + xMek1(mnr)"CA")
    *** cells: Ecoli<xRsk2(373-740)> in BMS
    *** unaffected by: xRsk2(373-740/K451A) [substitution]
    *** source: 12016217-Fig-2a
  *** rRsk2(mnr)"CTD"[phosAb] phos(Y529)[phosAb] is increased by rFgfR3{act}
    *** cells: none
    *** inhibited by: rRsk2(mnr/Y529F)"CTD" [substitution]
    *** source: 18156174-Fig-3
  *** rRsk2(mnr)"CTD"[phosAb] phos(Y529)[phosAb] is increased by rFyn{act}
    *** cells: none
    *** inhibited by: rRsk2(mnr/Y529F)"CTD" [substitution]
    *** source: 18156174-Fig-7
  *** rRsk2(mnr)"CTD"[phosAb] phos(Y529)[phosAb] is increased by rSrc{act}
    *** cells: none
    *** inhibited by: rRsk2(mnr/Y529F)"CTD" [substitution]
    *** source: 18156174-Fig-7
  *** rRsk2(mnr)"CTD"[phosAb] phos(Y529)[phosAb] is unchanged by rEgfR{act}
    *** cells: none
    *** source: 18156174-Fig-3
  *** rRsk2(mnr)"CTD"[phosAb] Yphos[pYAb] is increased by rFyn{act}
    *** cells: none
    *** unaffected by: rRsk2(mnr/Y529F)"CTD" [substitution]
    *** source: 18156174-Fig-7
  *** rRsk2(mnr)"CTD"[phosAb] Yphos[pYAb] is increased by rSrc{act}
    *** cells: none
    *** unaffected by: rRsk2(mnr/Y529F)"CTD" [substitution]
    *** source: 18156174-Fig-7
  *** Rsk2[Ab] prot-exp[WB] is detectable
    *** cells: mESCs in BMS
    *** does not req: Pdpk1 [KO]
    *** source: 11078882-Fig-1
  *** xRsk2[GST]IP phos(Y529)[phosAb] is increased itpo xFyn(Y528F)"CA"
    *** cells: HEK293T<xRsk2> in BMS
    *** inhibited by: xRsk2(Y529F) [substitution]
    *** source: 18156174-Fig-5
  *** xRsk2[GST]IP phos(Y529)[phosAb] is increased itpo xSrc(Y527F)"CA"
    *** cells: HEK293T<xRsk2> in BMS
    *** inhibited by: xRsk2(Y529F) [substitution]
    *** source: 18156174-Fig-5
  *** xRsk2[GST]IP Yphos[pYAb] is increased itpo xFyn(Y528F)"CA"
    *** cells: HEK293T<xRsk2> in BMS
    *** comment: phos sites were shown to be Y470,Y483,Y488,Y529,Y580,Y644,Y707 by MS
    *** source: 18156174-Fig-4a
  *** xRsk2[GST]IP Yphos[pYAb] is increased itpo xSrc(Y527F)"CA"
    *** cells: HEK293T<xRsk2> in BMS
    *** comment: phos sites were shown to be Y470,Y483,Y488,Y529,Y580,Y644,Y707 by MS
    *** source: 18156174-Fig-4a
  *** xRsk2[GST]IP Yphos[pYAb] is increased itpo xSrc(Y527F)"CA"
    *** cells: HEK293T<xRsk2> in BMS
    *** inhibited by: xRsk2(Y488F) [substitution]
    *** unaffected by: xRsk2(Y529F) [substitution]
    *** unaffected by: xRsk2(Y707F) [substitution]
    *** source: 18156174-Fig-4c
  *** xRsk2[GST]IP Yphos[pYAb] is unchanged itpo xFak1
    *** cells: HEK293T<xRsk2> in BMS
    *** source: 18156174-Fig-4a
  *** xRsk2[GST]IP Yphos[pYAb] is unchanged itpo xFak2
    *** cells: HEK293T<xRsk2> in BMS
    *** source: 18156174-Fig-4a
  *** xRsk2[tAb] copptby[WB] xFoxp3[tAb] is undetectable
    *** cells: HEK293T<xRsk2><xFoxp3> in BMS
    *** source: 15790681-Fig-4c
  *** xRsk2[tAb]IP IVKA(peptide)[32P-ATP] is increased by rErk1
    *** cells: COS7<xRsk2> in BMLS
    *** source: 8939914-Fig-6
  *** xRsk2[tAb]IP IVKA(peptide)[32P-ATP] is increased itpo xMek1(S218E/S222E)
    *** cells: COS7<xRsk2> in BMLS
    *** inhibited by: xMek1(S218A) [substitution]
    *** source: 8939914-Fig-2
  *** xRsk2[tAb]IP IVKA(Rps6)[32P-ATP] is increased itpo xPdpk1(51-556)
    *** cells: COS7<xRsk2> in BMLS
    *** source: 10480933-Fig-5
  *** xRsk2[tAb]IP IVKA(Rps6)[32P-ATP] is increased itpo xPdpk1(51-556)
    *** cells: COS7<xRsk2> in BMLS
    *** unaffected by: xPdpk1 [substitution]
    *** unaffected by: xPdpk1(51-458) [substitution]
    *** source: 10480933-Fig-6
*** Rsk3--
  *** rRsk3(1-360)[32P] phos[32P-ATP] is unchanged by xRsk2[tAb]IP
    *** cells: none
    *** IPfrom: COS7<xRsk3> in BMLS "treated with Egf for tnr"
    *** unaffected by: rRsk3(1-360/S227E) [substitution]
    *** source: 10480933-Fig-2
  *** Rsk3[Ab] prot-exp[WB] is detectable
    *** cells: mESCs in BMS
    *** does not req: Pdpk1 [KO]
    *** source: 11078882-Fig-1
  *** xRsk3[GST]IP IVKA(Crosstide)[32P-ATP] is decreased by Ro318220
    *** cells: HEK293<xRsk3> in BMLS
    *** source: 9687510-Fig-9a
  *** xRsk3[tAb]IP IVKA(peptide)[32P-ATP] is detectable-but unchanged by rErk1
    *** cells: CHO<xRsk3> in BMLS
    *** source: 8939914-Fig-6
  *** xRsk3[tAb]IP IVKA(peptide)[32P-ATP] is increased itpo xMek1(S218E/S222E)
    *** cells: COS7<xRsk3> in BMLS
    *** inhibited by: xMek1(S218A) [substitution]
    *** source: 8939914-Fig-2
*** Rsks--
  *** Rsks[Ab]IP IVKA(peptide)[32P-ATP] is detectable
    *** cells: mESCs in BMLS
    *** reqs: Pdpk1 [KO]
    *** inhibited by: kPdpk1(L155E) [substitution]
    *** source: 12912918-Fig-5
  *** Rsks[phosAb] phos(FSFV)[phosAb] is increased itpo xHras(Q61L)"CA"
    *** cells: HEK293E in BMLS
    *** inhibited by: U0126 [pretreatment]
    *** source: 17360704-Fig-2c
  *** Rsks[phosAb] phos(S227)[phosAb] is detectable
    *** cells: mESCs in BMLS
    *** reqs: Pdpk1 [KO]
    *** inhibited by: kPdpk1(L155E) [substitution]
    *** source: 12912918-Fig-5
  *** Rsks[phosAb] phos(S360)[phosAb] is detectable
    *** cells: mESCs in BMLS
    *** does not req: Pdpk1 [KO]
    *** unaffected by: kPdpk1(L155E) [substitution]
    *** source: 12912918-Fig-5
  *** Rsks[phosAb] phos(S380)[phosAb] is detectable
    *** cells: mESCs in BMLS
    *** does not req: Pdpk1 [KO]
    *** unaffected by: kPdpk1(L155E) [substitution]
    *** source: 12912918-Fig-5
  *** Rsks[phosAb] phos(T359/S363)[phosAb] is detectable
    *** cells: A375 in BMS
    *** unaffected by: Serum-depletion (tnr) [stress]
    *** source: 19274086-Fig-2b
  *** Rsks[phosAb] phos(T359/S363)[phosAb] is detectable
    *** cells: SKMEL28 in BMS
    *** unaffected by: Serum-depletion (tnr) [stress]
    *** source: 19274086-Fig-2b
  *** Rsks[phosAb] phos(T359/S363)[phosAb] is detectable
    *** cells: UACC903 in BMS
    *** unaffected by: Serum-depletion (tnr) [stress]
    *** source: 19274086-Fig-2b
  *** Rsks[phosAb] phos(T359/S363)[phosAb] is undetectable
    *** cells: MEWO in BMS
    *** unaffected by: Serum-depletion (tnr) [stress]
    *** source: 19274086-Fig-2b
  *** Rsks[phosAb] phos(T573)[phosAb] is detectable
    *** cells: mESCs in BMLS
    *** does not req: Pdpk1 [KO]
    *** unaffected by: kPdpk1(L155E) [substitution]
    *** source: 12912918-Fig-5
*** Ruvbl1--
  *** Ruvbl1[Ab] copptby[WB] Myc[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 10882073-Fig-1a
  *** Ruvbl1[Ab] copptby[WB] xRuvbl2[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 10882073-Fig-4b
  *** Ruvbl1[Ab] prot-exp[WB] is detectable
    *** cells: mEFs in BMLS
    *** reqs: Myc [KO]
    *** source: 10882073-Fig-7b
  *** Ruvbl1[Ab] prot-exp[WB] is increased itpo xMyc
    *** cells: mEFs<Myc~null> in BMLS
    *** source: 10882073-Fig-7b
  *** Ruvbl1[Ab] prot-exp[WB] is increased itpo xMycn
    *** cells: mEFs<Myc~null> in BMLS
    *** source: 10882073-Fig-7b
*** Ruvbl2--
  *** Ruvbl2[Ab] copptby[WB] Myc[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 10882073-Fig-1a
  *** Ruvbl2[Ab] copptby[WB] xRuvbl1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 10882073-Fig-4a
  *** Ruvbl2[Ab] prot-exp[WB] is detectable
    *** cells: mEFs in BMLS
    *** reqs: Myc [KO]
    *** source: 10882073-Fig-7b
  *** Ruvbl2[Ab] prot-exp[WB] is increased itpo xMyc
    *** cells: mEFs<Myc~null> in BMLS
    *** source: 10882073-Fig-7b
  *** Ruvbl2[Ab] prot-exp[WB] is increased itpo xMycn
    *** cells: mEFs<Myc~null> in BMLS
    *** source: 10882073-Fig-7b
*** S6k?--
  *** xS6k?[tAb]IP IVKA(peptide)[32P-ATP] is increased itpo xVps34
    *** cells: HEK293T in BMLS
    *** source: 16049009-Fig-1a
  *** xS6k?[tAb]IP phos(T252)[phosAb] is detectable
    *** cells: mESCs in BMLS
    *** reqs: Pdpk1 [KO]
    *** inhibited by: kPdpk1(L155E) [substitution]
    *** source: 12912918-Fig-4b
*** S6k1--
  *** xS6k1(mnr)"delC"[phosAb] phos(T412)[phosAb] is unchanged itpo xBnip3
    *** cells: HEK293<xS6k1(mnr)"delC"> in BMS
    *** source: 17928295-Fig-2c
  *** xS6k1(mnr)"delCT104"[tAb] copptby[WB] xRheb[tAb] is undetectable
    *** cells: HEK293T<xRheb><xS6k1(mnr)"delCT104"> in BMS
    *** source: 15854902-Fig-4a
  *** xS6k1(T412E)[tAb]IP IVKA(Rps6)[32P-ATP] is detectable
    *** cells: HEK293<xS6k1(T412E)> in BMLS
    *** source: 9632736-Fig-1a
  *** xS6k1(T444A/S447A)[tAb]IP IVKA(Rps6)[32P-ATP] is detectable
    *** cells: HEK293<xS6k1(T444A/S447A)> in BMLS
    *** source: 9632736-Fig-1a
  *** xS6k1[Ab] copptby[WB] xTsc2[tAb] is undetectable
    *** cells: HEK293<xTsc1><xTsc2><xS6k1> in BMLS
    *** source: 15342917-Fig-3a
  *** S6k1[Ab] phos[WBMS] is increased itao Pdk1 [KO]
    *** cells: mESCs in BMLS
    *** inhibited by: Rapamycin [addition]
    *** source: 15024086-Fig-5a
  *** S6k1[Ab] prot-exp[WB] is detectable
    *** cells: mESCs in BMS
    *** does not req: Pdpk1 [KO]
    *** source: 11078882-Fig-1
  *** S6k1[Ab] snaggedby[WB] rCdc42{GTPgS}[GST] is detectable
    *** cells: COS in BMS
    *** inhibited by: rCdc42{GDP} [substitution]
    *** source: 8653792-Fig-6b
  *** S6k1[Ab] snaggedby[WB] rRac1{GTPgS}[GST] is detectable
    *** cells: COS in BMS
    *** unaffected by: rRac1{GDP} [substitution]
    *** source: 8653792-Fig-6b
  *** S6k1[Ab] snaggedby[WB] rRhoa{GTPgS}[GST] is undetectable
    *** cells: COS in BMS
    *** unaffected by: rRhoa{GDP} [substitution]
    *** source: 8653792-Fig-6b
  *** S6k1[Ab]IP IVKA(Crosstide)[32P-ATP] is detectable
    *** cells: mESCs in BMLS
    *** reqs: Pdpk1 [KO]
    *** source: 10801415-Fig-4
  *** S6k1[phosAb] phos(S434)[phosAb] is detectable
    *** cells: rHepatocytes in BSS "containing Glucose"
    *** unaffected by: Glutamine (65 min) [stim]
    *** unaffected by: Leucine (15 min) [stim]
    *** unaffected by: Glutamine + Leucine (45 min) [stim]
    *** unaffected by: Aicar (20 min) [stim]
    *** unaffected by: CalyculinA (20 min) [stim]
    *** source: 12153572-Fig-6
  *** xS6k1[phosAb] phos(S434)[phosAb] is increased itpo Pik3c?(mnr)"CA"
    *** cells: HEK293<xS6k1> in BMLS
    *** bkg inhibited by: xS6k1(T252A) [substitution]
    *** source: 9632736-Fig-1b
  *** xS6k1[phosAb] phos(T252)[phosAb] is detectable
    *** cells: CHO<xInsR><xS6k1> in BMLS
    *** unaffected by: xS6k1(47-525)"delNT" [substitution]
    *** unaffected by: xS6k1(47-525/T412E)"delNT" [substitution]
    *** source: 9632736-Fig-4b
  *** xS6k1[phosAb] phos(T252)[phosAb] is increased itpo Pik3c?(mnr)"CA"
    *** cells: HEK293<xS6k1> in BMLS
    *** bkg inhibited by: xS6k1(T252A) [substitution]
    *** source: 9632736-Fig-1b
  *** S6k1[phosAb] phos(T412)[phosAb] is decreased irt BCH (60 min)
    *** cells: HELA in BMS "Serum- and AminoAcid-deprived, treated with (Ins + EAA + Glutamine) for 60 min"
    *** source: 19203585-Fig-3e
  *** S6k1[phosAb] phos(T412)[phosAb] is decreased irt DPhenylalanine (60 min)
    *** cells: HELA in BMS "Serum- and AminoAcid-deprived, treated with (EAA + Glutamine) for 60 min"
    *** source: 19203585-Fig-3f
  *** xS6k1[phosAb] phos(T412)[phosAb] is decreased itpo (xRagA + xRagB)
    *** cells: HELA<xS6k1> in BMS
    *** source: 18604198-Fig-5c
  *** xS6k1[phosAb] phos(T412)[phosAb] is decreased itpo (xRagA(T21N) + xRagC(Q120L))
    *** cells: HEK293<xS6k1> in BMS
    *** unaffected by: xRagA(T21N) + xRagC(Q120L) [addition]
    *** source: 18604198-Fig-5d
  *** xS6k1[phosAb] phos(T412)[phosAb] is decreased itpo (xRagA(T21N) + xRagC(Q120L))
    *** cells: HELA<xS6k1> in BMLS
    *** source: 18604198-Fig-3c
  *** xS6k1[phosAb] phos(T412)[phosAb] is decreased itpo (xTsc1 + xTsc2)
    *** cells: HEK293 in BMS
    *** reversed by: xTsc2(R261P) [substitution]
    *** reversed by: xTsc2(R611Q) [substitution]
    *** reversed by: xTsc2(E814K) [substitution]
    *** reversed by: xTsc2(R905Q) [substitution]
    *** reversed by: xTsc2(R1200W) [substitution]
    *** reversed by: xTsc2(N1645K) [substitution]
    *** reversed by: xTsc2(N1653S) [substitution]
    *** reversed by: xTsc2(N1683K) [substitution]
    *** reversed by: xTsc2(R1745P) [substitution]
    *** reversed by: xTsc2(R1747Q) [substitution]
    *** reversed by: xTsc2(R1751Q/R1753Q) [substitution]
    *** source: 12172553-Fig-2c
  *** xS6k1[phosAb] phos(T412)[phosAb] is decreased itpo (xTsc1 + xTsc2)
    *** cells: HEK293 in BMS
    *** source: 12172553-Fig-1b
  *** xS6k1[phosAb] phos(T412)[phosAb] is decreased itpo (xTsc1 + xTsc2)
    *** cells: HEK293 in BMS
    *** source: 12172553-Fig-1c
  *** xS6k1[phosAb] phos(T412)[phosAb] is decreased itpo (xTsc1 + xTsc2)
    *** cells: HEK293 in BMS
    *** source: 15340059-Fig-1c
  *** xS6k1[phosAb] phos(T412)[phosAb] is decreased itpo (xTsc1 + xTsc2)
    *** cells: HELA<xRheb> in BMLS
    *** reversed by: xRheb(N1643K) [substitution]
    *** source: 12820960-Fig-4c
  *** xS6k1[phosAb] phos(T412)[phosAb] is decreased itpo (xTsc1 + xTsc2)
    *** cells: U2OS<xS6k1> in BMS
    *** reversed by: xYwhab [addition]
    *** source: 12468542-Fig-4a
  *** xS6k1[phosAb] phos(T412)[phosAb] is decreased itpo xAxin1
    *** cells: HELA<xLkb1><xS6k1> in BMLS
    *** source: 16959574-Fig-4d
  *** xS6k1[phosAb] phos(T412)[phosAb] is decreased itpo xBnip3
    *** cells: HEK293<xS6k1> in BMS
    *** reversed by: xBnip3(31-194)"delN30" [substitution]
    *** unaffected by: xBnip3(del(110-15))"delBH3" [substitution]
    *** unaffected by: xBnip3(del(115-126))"delCD" [substitution]
    *** reversed by: xBnip3(115-194)"delN114" [substitution]
    *** reversed by: xBnip3(1-163)"delTM" [substitution]
    *** source: 17928295-Fig-2e
  *** xS6k1[phosAb] phos(T412)[phosAb] is decreased itpo xBnip3
    *** cells: HEK293<xS6k1> in BMS
    *** source: 17928295-Fig-2a
  *** S6k1[phosAb] phos(T412)[phosAb] is decreased itpo xDdit4
    *** cells: U2OS in BMS
    *** reversed by: xDdit4(mnr)"RPAA" [substitution]
    *** source: 18198340-Fig-4b
  *** S6k1[phosAb] phos(T412)[phosAb] is decreased itpo xDdit4
    *** cells: U2OS in BMS
    *** unaffected by: xAmpka2(K45R)"DN" [addition]
    *** source: 15988001-Fig-6a
  *** S6k1[phosAb] phos(T412)[phosAb] is decreased itpo xDdit4
    *** cells: U2OS in BMS
    *** unaffected by: xDdit4(del(96-156))"dC" [substitution]
    *** source: 15988001-Fig-5a
  *** xS6k1[phosAb] phos(T412)[phosAb] is decreased itpo xGsk3b(S9A)"CA"
    *** cells: HEK293<xS6k1> in BMS
    *** reversed by: Compound-C [addition]
    *** source: 16959574-Fig-7c
  *** xS6k1[phosAb] phos(T412)[phosAb] is decreased itpo xGsk3b(S9A)"CA"
    *** cells: HEK293<xS6k1> in BMS
    *** source: 16959574-Fig-4e
  *** xS6k1[phosAb] phos(T412)[phosAb] is decreased itpo xGsk3b(S9A)"CA"
    *** cells: HEK293<xS6k1> in BMS
    *** source: 16959574-Fig-5e
  *** S6k1[phosAb] phos(T412)[phosAb] is decreased itpo xPras40
    *** cells: EEF4 in BMS
    *** source: 17277771-Fig-2f
  *** S6k1[phosAb] phos(T412)[phosAb] is decreased itpo xPras40
    *** cells: EEF8<Tsc2~null> in BMS
    *** source: 17277771-Fig-2f
  *** S6k1[phosAb] phos(T412)[phosAb] is decreased itpo xPras40
    *** cells: HEK293T in BMS
    *** source: 17277771-Fig-2f
  *** xS6k1[phosAb] phos(T412)[phosAb] is decreased itpo xPras40
    *** cells: HEK293T<xS6k1> in BMS
    *** comment: decreased in phos mimics decrease in xS6k1 prot-exp
    *** unaffected by: xPras40(T246A) [substitution]
    *** source: 17277771-Fig-2c
  *** xS6k1[phosAb] phos(T412)[phosAb] is decreased itpo xPras40
    *** cells: HEK293T<xS6k1> in BMS
    *** reversed by: xYwha? [addition]
    *** source: 17277771-Fig-S4b
  *** xS6k1[phosAb] phos(T412)[phosAb] is decreased itpo xPras40
    *** cells: HEK293T<xS6k1> in BMS
    *** reversed by: xYwha? [addition]
    *** source: 17277771-Fig-S4c
  *** xS6k1[phosAb] phos(T412)[phosAb] is decreased itpo xPras40
    *** cells: HEK293T<xS6k1> in BMS
    *** reversed by: xYwha? [addition]
    *** source: 17277771-Fig-S4d
  *** xS6k1[phosAb] phos(T412)[phosAb] is decreased itpo xPras40
    *** cells: HEK293T<xS6k1> in BMS
    *** source: 17277771-Fig-S3f
  *** xS6k1[phosAb] phos(T412)[phosAb] is decreased itpo xPras40
    *** cells: HEK293T<xS6k1> in BMS
    *** unaffected by: xPras40(T246A) [substitution]
    *** source: 17277771-Fig-S4b
  *** xS6k1[phosAb] phos(T412)[phosAb] is decreased itpo xPras40
    *** cells: HEK293T<xS6k1> in BMS
    *** unaffected by: xPras40(T246A) [substitution]
    *** unaffected by: xPras40(T246D) [substitution]
    *** enhanced by: xPras40(T246E) [substitution]
    *** source: 17277771-Fig-S4d
  *** xS6k1[phosAb] phos(T412)[phosAb] is decreased itpo xPras40
    *** cells: HEK293T<xS6k1> in BMS
    *** unaffected by: xRheb [addition]
    *** source: 17277771-Fig-S3g
  *** xS6k1[phosAb] phos(T412)[phosAb] is decreased itpo xRagA(T21N)
    *** cells: HEK293<xS6k1> in BMS
    *** unaffected by: xRagC [addition]
    *** unaffected by: xRagC(S75N) [addition]
    *** unaffected by: xRagC(Q120L) [addition]
    *** source: 18604198-Fig-2b
  *** xS6k1[phosAb] phos(T412)[phosAb] is decreased itpo xRagA(T21N)
    *** cells: HEK293<xS6k1> in BMS
    *** unaffected by: xRagC(S75N) [addition]
    *** source: 18604198-Fig-2c
  *** S6k1[phosAb] phos(T412)[phosAb] is decreased itpo xTsc1
    *** cells: MDAMB453 in BMLS
    *** unaffected by: xTsc1(mnr)"SSAA" [substitution]
    *** reversed by: xTsc1(mnr)"SSAA" [substitution]
    *** source: 18949383-Fig-1b
  *** S6k1[phosAb] phos(T412)[phosAb] is decreased itpo xTsc2
    *** cells: EEF8<Tsc2~null> in BMS
    *** unaffected by: xTsc2(S1271A/S1387A) [substitution]
    *** source: 14651849-Fig-6c
  *** xS6k1[phosAb] phos(T412)[phosAb] is decreased itpo xTsc2
    *** cells: HEK293<xS6k1> in BMS
    *** source: 12869586-Fig-2e
  *** S6k1[phosAb] phos(T412)[phosAb] is decreased itpo xTsc2
    *** cells: LEF<Tsc2~null> in BMS
    *** reversed by: xTsc2(S1379A/S1383A/S1387A) [substitution]
    *** comment: aa numbers converted to Uniprot human canonical sequence
    *** source: 14651849-Fig-6d
  *** S6k1[phosAb] phos(T412)[phosAb] is decreased itpo xTsc2
    *** cells: LEF<Tsc2~null> in BMS
    *** source: 16959574-Fig-5d
  *** S6k1[phosAb] phos(T412)[phosAb] is decreased itpo xTsc2
    *** cells: LEF<Tsc2~null> in BMS
    *** unaffected by: xTsc2(S1254A) [substitution]
    *** comment: aa numbers converted to Uniprot human canonical sequence
    *** source: 12364343-Fig-4c
  *** S6k1[phosAb] phos(T412)[phosAb] is decreased itpo xTsc2
    *** cells: mEFs<Tsc1~null><Tp53~null> in BMLS
    *** inhibited by: xTsc2(S540A/S664A) [substitution]
    *** unaffected by: xTsc2(S540D/S664D) [substitution]
    *** source: 15851026-Fig-5f
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: 3T3L1 in BMLS "differentiated into adipocytes"
    *** inhibited by: Rapamycin [pretreatment]
    *** inhibited by: Wortmannin [pretreatment]
    *** unaffected by: U0126 [pretreatment]
    *** source: 17510057-Fig-3c
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: 3T3L1 in BMS
    *** does not req: Pras40 [RNAi]
    *** source: 17277771-Fig-2a
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: 786O in BMS
    *** inhibited by: xPld1(K898R)"CIA" [addition]
    *** inhibited by: xPld2(K758R)"CIA" [addition]
    *** source: 19114562-Fig-2d
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: bAECs in BMLS
    *** reqs: Rac1 [RNAi]
    *** source: 16339142(D)
  *** xS6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: CHO<xInsR><xS6k1> in BMLS
    *** unaffected by: xS6k1(47-525)"delNT" [substitution]
    *** inhibited by: xS6k1(47-525/T412E)"delNT" [substitution]
    *** source: 9632736-Fig-4b
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: EEF4 in BMS
    *** inhibited by: Rottlerin [addition]
    *** inhibited by: FCCP [addition]
    *** partially inhibited by: NaN3 [addition]
    *** partially inhibited by: Oligomycin [addition]
    *** partially inhibited by: Rotenone [addition]
    *** source: 14651849-Fig-3d
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: EEF8<Tsc2~null> in BMS
    *** partially inhibited by: Rottlerin [addition]
    *** partially inhibited by: FCCP [addition]
    *** unaffected by: NaN3 [addition]
    *** unaffected by: Oligomycin [addition]
    *** unaffected by: Rotenone [addition]
    *** source: 14651849-Fig-3d
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HEK293 in BMS
    *** partially reqs: Raptor [RNAi]
    *** source: 17043309-Fig-2b
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: Bnip3 [RNAi]
    *** source: 17928295-Fig-4b
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: Tsc2 [RNAi]
    *** source: 12172553-Fig-2b
  *** xS6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HEK293<xS6k1> in BMLS
    *** inhibited by: xS6k1(T412A) [substitution]
    *** inhibited by: xS6k1(T412E) [substitution]
    *** bkg inhibited by: xS6k1(T252A) [substitution]
    *** unaffected by: xS6k1(K123M) [substitution]
    *** unaffected by: xS6k1(S434A) [substitution]
    *** unaffected by: xS6k1(T444A/S447A) [substitution]
    *** source: 9632736-Fig-1a
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HEK293T in BMLS "Leucine-deprived"
    *** reqs: Rheb [RNAi]
    *** source: 18497260-Fig-3b
  *** xS6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HEK293T<xPras40><xS6k1> in BMS
    *** unaffected by: xPras40(1-150) [substitution]
    *** inhibited by: xPras40(103-258) [substitution]
    *** unaffected by: xPras40(142-258) [substitution]
    *** unaffected by: xPras40(150-258) [substitution]
    *** inhibited by: xPras40(1-234) [substitution]
    *** unaffected by: xPras40(150-234) [substitution]
    *** source: 17277771-Fig-2d
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HELA in BMS
    *** does not req: Rictor [RNAi]
    *** source: 19446321-Fig-4g
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HELA in BMS
    *** partially reqs: Raptor [RNAi]
    *** source: 17043309-Fig-2a
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HELA in BMS
    *** reqs: Mtor [RNAi]
    *** source: 19203585-Fig-5b
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HELA in BMS
    *** reqs: Raptor [RNAi]
    *** source: 19446321-Fig-4g
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HELA in BMS
    *** reqs: Slc1a5 [RNAi]
    *** source: 19203585-Fig-5b
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HELA in BMS
    *** reqs: Slc3a2 [RNAi]
    *** source: 19203585-Fig-5b
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HELA in BMS
    *** reqs: Slc7a5 [RNAi]
    *** source: 19203585-Fig-5b
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HEPG2 in BMS
    *** does not req: Pras40 [RNAi]
    *** source: 17277771-Fig-2a
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HT29 in BMLS
    *** reqs: Raptor [RNAi]
    *** source: 17386266-Fig-5e
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: HT29 in BMS
    *** reqs: Raptor [RNAi]
    *** source: 17386266-Fig-5e
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: LEF<Tsc2~null><xTsc2> in BMS
    *** enhanced by: xTsc2(S1371A/S1375A/S1337A/S1383A) [substitution]
    *** comment: aa numbers converted to Uniprot human canonical sequence
    *** source: 16959574-Fig-S7b
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: MDAMB453 in BMS
    *** reqs: Ikk2 [RNAi]
    *** source: 17693255-Fig-2f
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: mEFs in BMLS
    *** partially reqs: Ctnnb1 [KO]
    *** source: 16959574-Fig-4h
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: mEFs in BMLS
    *** reqs: Raptor [RNAi]
    *** source: 17386266-Fig-5e
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: mEFs in BMLS
    *** unaffected by: AA-deprivation [addition]
    *** unaffected by: AA-deprivation + CHX [addition]
    *** source: 15772076-Fig-4a
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: mEFs in BMS
    *** reqs: Ikk2 [KO]
    *** source: 17693255-Fig-2e
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: mEFs in BMS
    *** reqs: Raptor [RNAi]
    *** source: 17386266-Fig-5e
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: mEFs in BMS
    *** unaffected by: Ddit4 [KO]
    *** source: 18198340-Fig-1
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: mEFs in BMS
    *** unaffected by: Tsc2 [KO]
    *** source: 18198340-Fig-1
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: mESCs in BMLS
    *** reqs: Pdpk1 [KO]
    *** source: 10801415-Fig-4
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: NIH3T3 in BMS
    *** does not req: Rictor [RNAi]
    *** source: 15467718-Fig-4a
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: NIH3T3 in BMS
    *** reqs: Mlst8 [RNAi]
    *** source: 15467718-Fig-4a
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: NIH3T3 in BMS
    *** reqs: Mtor [RNAi]
    *** source: 15467718-Fig-4a
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: NIH3T3 in BMS
    *** reqs: Raptor [RNAi]
    *** source: 15467718-Fig-4a
  *** S6k1[phosAb] phos(T412)[phosAb] is detectable
    *** cells: RPMI8226 in BMS
    *** reqs: Raptor [RNAi]
    *** source: 19446321-Fig-S9
  *** xS6k1[phosAb] phos(T412)[phosAb] is detectable-but unchanged itpo xPras40
    *** cells: HEK293T<xS6k1> in BMS
    *** comment: author says this is a decrease
    *** source: 17277771-Fig-2b
  *** xS6k1[phosAb] phos(T412)[phosAb] is detectable-but unchanged itpo xRagA
    *** cells: HEK293<xS6k1> in BMS
    *** inhibited by: xRagA(T21N)"GDP" [substitution]
    *** unaffected by: xRagA(Q66L)"GTP" [substitution]
    *** source: 18604198-Fig-2a
  *** xS6k1[phosAb] phos(T412)[phosAb] is detectable-but unchanged itpo xRagA
    *** cells: HEK293<xS6k1> in BMS
    *** unaffected by: xRagC [addition]
    *** source: 18604198-Fig-2c
  *** xS6k1[phosAb] phos(T412)[phosAb] is detectable-but unchanged itpo xRagA(Q66L)
    *** cells: HEK293<xS6k1> in BMS
    *** unaffected by: xRagC(Q120L) [addition]
    *** source: 18604198-Fig-2c
  *** xS6k1[phosAb] phos(T412)[phosAb] is detectable-but unchanged itpo xRagB
    *** cells: HEK293<xS6k1> in BMS
    *** inhibited by: xRagB(T54N)"GDP" [substitution]
    *** unaffected by: xRagB(Q99L)"GTP" [substitution]
    *** source: 18604198-Fig-2a
  *** xS6k1[phosAb] phos(T412)[phosAb] is detectable-but unchanged itpo xRagC
    *** cells: HEK293<xS6k1> in BMS
    *** unaffected by: xRagA [addition]
    *** source: 18604198-Fig-2c
  *** xS6k1[phosAb] phos(T412)[phosAb] is detectable-but unchanged itpo xRagC
    *** cells: HEK293<xS6k1> in BMS
    *** unaffected by: xRagC(S75N)"GDP" [substitution]
    *** unaffected by: xRagC(Q120L)"GTP" [substitution]
    *** source: 18604198-Fig-2a
  *** xS6k1[phosAb] phos(T412)[phosAb] is detectable-but unchanged itpo xRagC(Q120L)
    *** cells: HEK293<xS6k1> in BMS
    *** unaffected by: xRagA(Q120L) [addition]
    *** source: 18604198-Fig-2c
  *** xS6k1[phosAb] phos(T412)[phosAb] is detectable-but unchanged itpo xRagC(Q120L)
    *** cells: HEK293<xS6k1> in BMS "AminoAcid-deprived"
    *** source: 18604198-Fig-3a
  *** xS6k1[phosAb] phos(T412)[phosAb] is detectable-but unchanged itpo xRagC(S75N)
    *** cells: HEK293<xS6k1> in BMS
    *** inhibited by: xRagA(T21N) [addition]
    *** source: 18604198-Fig-2c
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Ddit4 [KO]
    *** cells: mEFs in BMS
    *** source: 18198340-Fig-1
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Deptor [RNAi]
    *** cells: HELA in BMS
    *** source: 19446321-Fig-2a
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Deptor [RNAi]
    *** cells: mEFs<Tp53~null> in BMS
    *** source: 19446321-Fig-2a
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Deptor [RNAi]
    *** cells: RPMI8226 in BMS
    *** source: 19446321-Fig-6e
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Deptor [RNAi]
    *** cells: RPMI8226 in BMS
    *** source: 19446321-Fig-S9
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Gsk3a and Gsk3b [RNAi]
    *** cells: HEK293 in BMS
    *** source: 16959574-Fig-4f
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Maf [RNAi]
    *** cells: RPMI8226 in BMS
    *** source: 19446321-Fig-6j
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Raptor [RNAi]
    *** cells: HT29 in BMLS
    *** source: 17386266-Fig-5e
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Raptor [RNAi]
    *** cells: HT29 in BMS
    *** source: 17386266-Fig-5e
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Raptor [RNAi]
    *** cells: mEFs in BMLS
    *** source: 17386266-Fig-5e
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Raptor [RNAi]
    *** cells: mEFs in BMS
    *** source: 17386266-Fig-5e
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Tsc1 [KO]
    *** cells: mEFs in BMLS
    *** source: 17693255-Fig-4a
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Tsc1 [KO]
    *** cells: mEFs in BMS
    *** source: 18198340-Fig-1
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Tsc1 and Tsc2 [RNAi]
    *** cells: OCIMY5 in BMS
    *** source: 19446321-Fig-S8
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Tsc2 [KO]
    *** cells: mEFs in BMLS
    *** inhibited by: AA-deprivation (90 min) [pretreatment]
    *** source: 15772076-Fig-3f
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Tsc2 [KO]
    *** cells: mEFs in BMLS
    *** inhibited by: AA-deprivation [addition]
    *** unaffected by: AA-deprivation + CHX [addition]
    *** inhibited by: Rapamycin [addition]
    *** source: 15772076-Fig-4a
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Tsc2 [KO]
    *** cells: mEFs in BMLS
    *** inhibited by: Aicar [cotreatment]
    *** partially inhibited by: Phenformin [cotreatment]
    *** source: 18439900-Fig-2a
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Tsc2 [KO]
    *** cells: mEFs in BMLS
    *** source: 15772076-Fig-3a
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Tsc2 [KO]
    *** cells: mEFs in BMLS
    *** source: 16027121-Fig-6a
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Tsc2 [KO]
    *** cells: mEFs in BMLS "Serum deprived"
    *** source: 16176982-Fig-1d
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Tsc2 [KO]
    *** cells: mEFs in BMS
    *** source: 15545625-Fig-1b
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Tsc2 [KO]
    *** cells: mEFs in BMS
    *** unaffected by: xAkt1(myr)"CA" [addition]
    *** source: 16027121-Fig-6c
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Tsc2 [KO]
    *** cells: mEFs in BMS "AminoAcid-deprived and Serum-deprived"
    *** enhanced by: AminoAcids (10 min) [stim]
    *** enhanced by: Serum (10 min) [stim]
    *** source: 20381137-Fig-S1d
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Tsc2 [KO]
    *** cells: mEFs in BMS "AminoAcid-deprived"
    *** reqs: Rheb [RNAi]
    *** source: 20381137-Fig-S1e
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Tsc2 [KO]
    *** cells: mEFs in BMS "Leucine deprived"
    *** source: 17386266-Fig-S1
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Tsc2 [KO]
    *** cells: mEFs<Tp53~null> in BMLS
    *** inhibited by: Rapamycin [pretreatment]
    *** source: 15545625-Fig-1a
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Tsc2 [KO]
    *** cells: mEFs<Tp53~null> in BMLS
    *** source: 17693255-Fig-4a
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Tsc2 [KO]
    *** cells: mEFs<Tp53~null> in BMLS
    *** unaffected by: Serum (45 min) [stim]
    *** source: 15545625-Fig-1a
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itao Tsc2 [RNAi]
    *** cells: HEK293 in BMS
    *** source: 12172553-Fig-2a
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itao Tsc2 [RNAi]
    *** cells: HEK293<xS6k1> in BMS
    *** unaffected by: xGsk3b(S9A)"CA" [addition]
    *** source: 16959574-Fig-5e
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itao Tsc2 [RNAi]
    *** cells: HEK293T<xS6k1> in BMS
    *** source: 17277771-Fig-S3f
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Tsc2 [RNAi]
    *** cells: HELA in BMLS "Serum and AminoAcid deprived"
    *** comment: increase is almost below level of detection
    *** source: 16176982-Fig-1c
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Tsc2 [RNAi]
    *** cells: HELA in BMLS "Serum deprived"
    *** source: 16176982-Fig-1c
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itao Tsc2 [RNAi]
    *** cells: HELA<xS6k1> in BMS
    *** partially reversed by: xRagA + xRagB [addition]
    *** source: 18604198-Fig-5c
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Tsc2 [RNAi]
    *** cells: mEFs in BMLS
    *** source: 17386266-Fig-1e
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itao Tsc2 [RNAi]
    *** cells: mEFs in BMLS
    *** source: 18570873-Fig-7g
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo (xRagA(Q66L) + xRagC(S75N))
    *** cells: HEK293<xS6k1> in BMS "AminoAcid-deprived"
    *** inhibited by: Rapamycin [addition]
    *** source: 18604198-Fig-5a
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo (xRagA(Q66L) + xRagC(S75N))
    *** cells: HEK293<xS6k1> in BMS "AminoAcid-deprived"
    *** inhibited by: xMtor(mnr)"KD" [addition]
    *** source: 18604198-Fig-5a
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo (xRagA(Q66L) + xRagC(S75N))
    *** cells: HEK293<xS6k1> in BMS "AminoAcid-deprived"
    *** partially inhibited by: xTsc1 + xTsc2 [addition]
    *** source: 18604198-Fig-5b
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itpo (xRagB(Q99L)"GTP" + xRagC(S75L)"GDP")
    *** cells: HEK293T in BMS
    *** unaffected by: xSlc36a1 [addition]
    *** source: 22053050-Fig-4c
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo Pik3c?(mnr)"CA"
    *** cells: HEK293<xS6k1> in BMLS
    *** bkg inhibited by: xS6k1(T252A) [substitution]
    *** source: 9632736-Fig-1b
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xAkt1
    *** cells: HEK293 in BMS
    *** source: 12172553-Fig-1b
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xAkt1
    *** cells: HEK293 in BMS
    *** source: 12172553-Fig-5a
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xAkt1
    *** cells: HEK293T<xS6k1><xPras40> in BMS
    *** inhibited by: xPras40(T246A) [substitution]
    *** source: 17277771-Fig-2c
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xAkt1(myr)
    *** cells: HEK293E<xS6k1> in BMLS
    *** inhibited by: xPras40 [addition]
    *** inhibited by: xPras40(T246A) [addition]
    *** comment: inhibition by xPras40(T246A) is greater than xPras40(WT)
    *** source: 17386266-Fig-7d
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xAkt1(myr)
    *** cells: HEK293T<xS6k1> in BMS
    *** inhibited by: xPras40 [addition]
    *** inhibited by: xPras40(T246A) [addition]
    *** source: 17277771-Fig-S4c
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xAkt1(myr)
    *** cells: HEK293T<xS6k1> in BMS
    *** unaffected by: xYwha? [addition]
    *** comment: decreased in xS6k1 prot-exp caused increase in phosS6k1/totalS6k1
    *** source: 17277771-Fig-S4c
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itpo xAkt1(myr)"CA"
    *** cells: HC11 in BMLS "containing Ins"
    *** source: 16984645-Fig-4d
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itpo xAkt1(myr)"CA"
    *** cells: RAT1A in BMLS
    *** source: 16027121-Fig-2f
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itpo xAkt1(myr)"CA"
    *** cells: RAT1A in BMS
    *** source: 16027121-Fig-2f
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xDvl2
    *** cells: HEK293<xS6k1> in BMS
    *** source: 16959574-Fig-4b
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xDvl2
    *** cells: HEK293<xS6k1> in BMS "Glucose-deprived"
    *** source: 16959574-Fig-4b
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xHras(G12V)
    *** cells: HEK293<xS6k1> in BMLS
    *** does not req: Rsk1 [RNAi]
    *** source: 15851026-Fig-5g
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xHras(G12V)
    *** cells: HEK293<xS6k1> in BMLS
    *** partially inhibited by: U0126 [pretreatment]
    *** partially inhibited by: Wortmannin [pretreatment]
    *** comment: inhibited to below bkg by (U0126 + Wortmannin)
    *** source: 15851026-Fig-5b
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xHras(G12V)
    *** cells: HEK293<xS6k1> in BMLS
    *** partially inhibited by: xTsc1 + xTsc2 [addition]
    *** inhibited by: xTsc1 + xTsc2(S540A/S664A) [addition]
    *** partially inhibited by: xTsc1 + xTsc2(S540D/S664D) [addition]
    *** source: 15851026-Fig-5d
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xHras(G12V)"CA"
    *** cells: HEK293 in BMS
    *** source: 12172553-Fig-1b
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xHras(G12V)"CA"
    *** cells: HEK293 in BMS
    *** source: 12172553-Fig-1c
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xHras(G12V)"CA"
    *** cells: HEK293<xS6k1> in BMS
    *** bkg inhibited by: BSS (30 min) [stim]
    *** source: 12869586-Fig-4a
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xHras(G12V)"CA"
    *** cells: HEK293<xS6k1> in BMS
    *** bkg inhibited by: Rapamycin (30 min) [stim]
    *** source: 12869586-Fig-4a
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itpo xIkk2
    *** cells: HBL100 in BMS
    *** inhibited by: xIkk2(mnr)"KD" [substitution]
    *** source: 17693255-Fig-2d
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itpo xIkk2
    *** cells: MCF7 in BMS
    *** inhibited by: xIkk2(mnr)"KD" [substitution]
    *** source: 17693255-Fig-2a
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itpo xIkk2
    *** cells: MCF7 in BMS
    *** source: 17693255-Fig-2b
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itpo xIkk2
    *** cells: MDAMB453 in BMS
    *** source: 17693255-Fig-2a
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itpo xIkk2
    *** cells: mEFs in BMLS
    *** inhibited by: xIkk2(mnr)"KD" [substitution]
    *** source: 17693255-Fig-4b
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itpo xIkk2
    *** cells: mEFs<Ikk1~null> in BMS
    *** source: 17693255-Fig-2e
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itpo xIkk2
    *** cells: mEFs<Ikk2~null> in BMS
    *** source: 17693255-Fig-2e
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xMek1(S281D/S222D)
    *** cells: HEK293<xS6k1> in BMLS
    *** does not req: Rsk1 [RNAi]
    *** source: 15851026-Fig-5g
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xMek1(S281D/S222D)
    *** cells: HEK293<xS6k1> in BMLS
    *** partially inhibited by: xTsc1 + xTsc2 [addition]
    *** inhibited by: xTsc1 + xTsc2(S540A/S664A) [addition]
    *** partially inhibited by: xTsc1 + xTsc2(S540D/S664D) [addition]
    *** source: 15851026-Fig-5c
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itpo xMtor
    *** cells: WM35 in BMS
    *** comment: subject was published as Sgk1 phos(S422) but was shown by 18925875 to be S6k1(T412)
    *** source: 18570873-Fig-3a
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itpo xMtor
    *** cells: WM35 in BMS
    *** comment: subject was published as Sgk1 phos(S422) but was shown by 18925875 to be S6k1(T412)
    *** source: 18570873-Fig-3b
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xRagA(Q66L)
    *** cells: HEK293<xS6k1> in BMS
    *** enhanced by: xRagC [addition]
    *** enhanced by: xRagC(S75N) [addition]
    *** enhanced by: xRagC(Q120L) [addition]
    *** source: 18604198-Fig-2b
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xRagA(Q66L)
    *** cells: HEK293<xS6k1> in BMS "AminoAcid-deprived"
    *** source: 18604198-Fig-3a
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xRagA(Q66L)
    *** cells: HEK293<xS6k1> in BMS "AminoAcid-deprived"
    *** source: 18604198-Fig-S2a
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itpo xRagA(Q66L)"GTP"
    *** cells: mEFs in BMS "AminoAcid-deprived"
    *** unaffected by: AminoAcids (10 min) [stim]
    *** unaffected by: SalicylihalamideA [cotreatment]
    *** source: 22053050-Fig-2f
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itpo xRagB
    *** cells: HEK293T in BMS "AminoAcids-deprived"
    *** enhanced by: xRagB(Q99L)"GTP" [substitution]
    *** source: 18497260-Fig-3c
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itpo xRagB
    *** cells: HEK293T in BMS "Leucine-deprived"
    *** enhanced by: xRagB(Q99L)"GTP" [substitution]
    *** source: 18497260-Fig-3b
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itpo xRagB(Q99L)"GTP"
    *** cells: HEK293T in BMS "AminoAcid-deprived"
    *** unaffected by: AminoAcids (10 min) [stim]
    *** unaffected by: SalicylihalamideA [cotreatment]
    *** source: 22053050-Fig-2e
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itpo xRagB(Q99L)"GTP"
    *** cells: HEK293T<xS6k1> in BMLS "AminoAcids-deprived"
    *** inhibited by: xRagB [substitution]
    *** source: 18497260-Fig-S3
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xRagC
    *** cells: HEK293<xS6k1><xRagA> in BMS
    *** source: 18604198-Fig-2b
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xRagC(S75N)
    *** cells: HEK293<xS6k1> in BMS "AminoAcid-deprived"
    *** source: 18604198-Fig-3a
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xRheb
    *** cells: HEK293 in BMS
    *** inhibited by: xTsc1 + xTsc2 [addition]
    *** source: 15340059-Fig-1c
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xRheb
    *** cells: HEK293 in BMS
    *** inhibited by: xTsc2 [addition]
    *** unaffected by: xTsc2(K1595Q/K1596Q/K1597Q) [addition]
    *** source: 15340059-Fig-5c
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xRheb
    *** cells: HEK293 in BMS
    *** inhibited by: xTsc2 [addition]
    *** unaffected by: xTsc2(R1701P) [addition]
    *** unaffected by: xTsc2(R1703P) [addition]
    *** inhibited by: xTsc2(R1707Q/R1709Q) [addition]
    *** source: 15340059-Fig-5b
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itpo xRheb
    *** cells: HEK293 in BMS
    *** source: 12869586-Fig-2a
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xRheb
    *** cells: HEK293 in BMS
    *** unaffected by: xRheb(Q64L)"CA" [substitution]
    *** inhibited by: xRheb(mnr)"5A" [substitution]
    *** inhibited by: xRheb(mnr)"N20" [substitution]
    *** source: 12869586-Fig-2c
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xRheb
    *** cells: HEK293 in BMS
    *** unaffected by: xRheb(R15G) [substitution]
    *** source: 15340059-Fig-1c
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xRheb
    *** cells: HEK293<xS6k1> in BMLS
    *** inhibited by: xTsc1 + xTsc2 [addition]
    *** inhibited by: xTsc1 + xTsc2(S540A/S664A) [addition]
    *** partially inhibited by: xTsc1 + xTsc2(S540D/S664D) [addition]
    *** source: 15851026-Fig-5e
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xRheb
    *** cells: HEK293<xS6k1> in BMS
    *** bkg inhibited by: Rapamycin (30 min) [stim]
    *** source: 12869586-Fig-4a
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xRheb
    *** cells: HEK293<xS6k1> in BMS
    *** inhibited by: xMtor(mnr)"KD" [addition]
    *** source: 12869586-Fig-4b
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xRheb
    *** cells: HEK293<xS6k1> in BMS
    *** inhibited by: xTsc1 + xTsc2 [addition]
    *** source: 12869586-Fig-3a
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xRheb
    *** cells: HEK293<xS6k1> in BMS
    *** source: 12869586-Fig-2a
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xRheb
    *** cells: HEK293<xS6k1> in BMS
    *** source: 12869586-Fig-2b
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xRheb
    *** cells: HEK293<xS6k1> in BMS
    *** source: 12869586-Fig-2d
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xRheb
    *** cells: HEK293<xS6k1> in BMS
    *** unaffected by: BSS (30 min) [stim]
    *** source: 12869586-Fig-4a
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xRheb
    *** cells: HEK293<xS6k1> in BMS
    *** unaffected by: xRagA(T21N) + xRagC(Q120L) [addition]
    *** source: 18604198-Fig-5d
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xRheb
    *** cells: HEK293<xS6k1> in BSS
    *** partially inhibited by: xBnip3 [addition]
    *** source: 17928295-Fig-3a
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xRheb
    *** cells: HEK293E<xS6k1> in BMLS
    *** bkg inhibited by: xPras40 [addition]
    *** source: 17386266-Fig-5b
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itpo xRheb
    *** cells: HEK293T in BMLS
    *** source: 12842888-Fig-5
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xRheb
    *** cells: HEK293T<xS6k1> in BMLS
    *** bkg inhibited by: xPras40 [addition]
    *** source: 17386266-Fig-5b
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xRheb
    *** cells: HEK293T<xS6k1> in BMS
    *** inhibited by: xPras40 [addition]
    *** source: 17277771-Fig-S3g
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xRheb
    *** cells: HEK293T<xS6k1> in BMS
    *** inhibited by: xRheb(S20N) [substitution]
    *** partially inhibited by: xRheb(T38M) [substitution]
    *** unaffected by: xRheb(N41A) [substitution]
    *** inhibited by: xRheb(I39K) [substitution]
    *** inhibited by: xRheb(D60I) [substitution]
    *** inhibited by: xRheb(C181S) [substitution]
    *** source: 15854902-Fig-1a
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xRheb
    *** cells: HELA<xS6k1> in BMLS
    *** bkg inhibited by: Rapamycin [pretreatment]
    *** unaffected by: Wortmannin [pretreatment]
    *** source: 12820960-Fig-4a
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xRheb
    *** cells: HELA<xS6k1> in BMLS
    *** partially inhibited by: 2DOG [pretreatment]
    *** source: 12820960-Fig-4a
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xRheb
    *** cells: HELA<xS6k1> in BMLS
    *** reqs: Rheb [RNAi]
    *** source: 12820960-Fig-3d
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xRheb
    *** cells: HELA<xS6k1> in BMLS
    *** source: 12820960-Fig-2c
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xRheb(Q64L)
    *** cells: HEK293T<xS6k1> in BMS
    *** bkg inhibited by: xPras40 [addition]
    *** source: 17277771-Fig-S3h
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xRheb(Q64L)"CA"
    *** cells: HEK293 in BMS
    *** inhibited by: xTsc1 + xTsc2 [addition]
    *** source: 15340059-Fig-2b
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xRheb(Q64L)"CA"
    *** cells: HEK293 in BMS
    *** partially inhibited by: xRheb(Q64L/C181S) [substitution]
    *** source: 15340059-Fig-2c
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xRheb(Q64L)"CA"
    *** cells: HEK293<xS6k1> in BMS
    *** unaffected by: BSS (30 min) [stim]
    *** unaffected by: 1Butanol (30 min) [stim]
    *** bkg inhibited by: Sorbitol (30 min) [stim]
    *** unaffected by: 2DOG (30 min) [stim]
    *** bkg inhibited by: Rapamycin (30 min) [stim]
    *** source: 12869586-Fig-4d
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itpo xRheb(Q64L)"GTP"
    *** cells: HEK293T<xS6k1> in BMLS "AminoAcids-deprived"
    *** inhibited by: xRheb [substitution]
    *** source: 18497260-Fig-S3
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itpo xTsc2
    *** cells: LEF<Tsc2~null> in BMS
    *** inhibited by: xTsc2(S1371A/S1375A/S1337A/S1383A) [substitution]
    *** comment: aa numbers converted to Uniprot human canonical sequence
    *** source: 16959574-Fig-7f
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xVps15
    *** cells: GRCLR73 in BMLS
    *** source: 16049009-Fig-1b
  *** S6k1[phosAb] phos(T412)[phosAb] is increased itpo xVps15
    *** cells: HELA in BMLS
    *** reqs: Vps34 [RNAi]
    *** source: 16049009-Fig-1g
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xVps34
    *** cells: GRCLR73 in BMLS
    *** source: 16049009-Fig-1b
  *** xS6k1[phosAb] phos(T412)[phosAb] is increased itpo xYwha?
    *** cells: HEK293T<xS6k1><xPras40> in BMS
    *** inhibited by: xPras40(T246A) [substitution]
    *** inhibited by: xPras40(T246D) [substitution]
    *** bkg inhibited by: xPras40(T246E) [substitution]
    *** source: 17277771-Fig-S4d
  *** S6k1[phosAb] phos(T412)[phosAb] is unchanged itao Tsc2 [KO]
    *** cells: mEFs in BMLS "Serum and AminoAcid deprived"
    *** source: 16176982-Fig-1d
  *** S6k1[phosAb] phos(T412)[phosAb] is unchanged itpo xAkt1(myr)"CA"
    *** cells: mEFs<Tsc2~null> in BMS
    *** source: 16027121-Fig-6c
  *** S6k1[phosAb] phos(T412)[phosAb] is unchanged itpo xAkt1(myr)"CA"
    *** cells: mEFs<Tsc2~null><xTsc2(S939D/S1086D/S1088E/T1422E)> in BMS
    *** source: 16027121-Fig-7b
  *** xS6k1[phosAb] phos(T412)[phosAb] is unchanged itpo xBnip3l
    *** cells: HEK293<xS6k1> in BMS
    *** source: 17928295-Fig-2a
  *** xS6k1[phosAb] phos(T412)[phosAb] is unchanged itpo xCdc42(Q61L)"CA"
    *** cells: HEK293<xS6k1> in BMS
    *** source: 12869586-Fig-2d
  *** xS6k1[phosAb] phos(T412)[phosAb] is unchanged itpo xCtnnb1(mnr)"CA"
    *** cells: HEK293<xS6k1> in BMS
    *** source: 16959574-Fig-4g
  *** S6k1[phosAb] phos(T412)[phosAb] is unchanged itpo xIkk1
    *** cells: mEFs<Ikk1~null> in BMS
    *** source: 17693255-Fig-2e
  *** S6k1[phosAb] phos(T412)[phosAb] is unchanged itpo xIkk1
    *** cells: mEFs<Ikk2~null> in BMS
    *** source: 17693255-Fig-2e
  *** xS6k1[phosAb] phos(T412)[phosAb] is unchanged itpo xRab5a(Q79L)"CA"
    *** cells: HEK293<xS6k1> in BMS
    *** source: 12869586-Fig-2d
  *** xS6k1[phosAb] phos(T412)[phosAb] is unchanged itpo xRagA
    *** cells: HEK293<xS6k1> in BMS "AminoAcid-deprived"
    *** unaffected by: xRagC [addition]
    *** source: 18604198-Fig-3a
  *** xS6k1[phosAb] phos(T412)[phosAb] is unchanged itpo xRagA(T21N)
    *** cells: HEK293<xS6k1> in BMS "AminoAcid-deprived"
    *** source: 18604198-Fig-3a
  *** xS6k1[phosAb] phos(T412)[phosAb] is unchanged itpo xRagC
    *** cells: HEK293<xS6k1> in BMS "AminoAcid-deprived"
    *** unaffected by: xRagA [addition]
    *** source: 18604198-Fig-3a
  *** xS6k1[phosAb] phos(T412)[phosAb] is unchanged itpo xRap1a(G12V)"CA"
    *** cells: HEK293<xS6k1> in BMS
    *** source: 12869586-Fig-2d
  *** S6k1[phosAb] phos(T412)[phosAb] is unchanged itpo xRela
    *** cells: MCF7 in BMLS
    *** source: 17693255-Fig-1e
  *** xS6k1[phosAb] phos(T412)[phosAb] is unchanged itpo xRhoa(Q63L)"CA"
    *** cells: HEK293<xS6k1> in BMS
    *** source: 12869586-Fig-2d
  *** xS6k1[phosAb] phos(T412)[phosAb] is unchanged itpo xTsc1
    *** cells: HEK293<xS6k1> in BMS
    *** source: 12869586-Fig-2e
  *** S6k1[phosAb] phos(T412)[phosAb] is unchanged itpo xVps34
    *** cells: HEK293 in BMLS "Serum and AminoAcid deprived"
    *** source: 16176982-Fig-4a
  *** xS6k1[phosAb] phos(T412)[phosAb] is unchanged itpo xYwha?
    *** cells: HEK293T<xS6k1> in BMS
    *** source: 17277771-Fig-S4c
  *** xS6k1[phosAb] phos(T434)[phosAb] is detectable
    *** cells: CHO<xInsR><xS6k1> in BMLS
    *** unaffected by: xS6k1(47-525)"delNT" [substitution]
    *** unaffected by: xS6k1(47-525/T412E)"delNT" [substitution]
    *** source: 9632736-Fig-4b
  *** xS6k1[phosAb] phos(T444/S447)[phosAb] is detectable
    *** cells: CHO<xInsR><xS6k1> in BMLS
    *** unaffected by: xS6k1(47-525)"delNT" [substitution]
    *** unaffected by: xS6k1(47-525/T412E)"delNT" [substitution]
    *** source: 9632736-Fig-4b
  *** S6k1[phosAb] phos(T444/S447)[phosAb] is detectable
    *** cells: HELA in BMLS
    *** does not req: Vps34 [RNAi]
    *** source: 16049009-Fig-5a
  *** S6k1[phosAb] phos(T444/S447)[phosAb] is detectable
    *** cells: HEPG2 in BMLS "plated on collagen"
    *** partially inhibited by: Gefitinib [cotreatment]
    *** inhibited by: PD325901 [cotreatment]
    *** unaffected by: BMS345541 [cotreatment]
    *** unaffected by: PHA818637 [cotreatment]
    *** unaffected by: ZSTK474 [cotreatment]
    *** source: 19953085-Fig-S1
  *** xS6k1[phosAb] phos(T444/S447)[phosAb] is detectable-but unchanged itpo xRagA
    *** cells: HEK293<xS6k1> in BMS
    *** unaffected by: xRagC [addition]
    *** source: 18604198-Fig-2c
  *** xS6k1[phosAb] phos(T444/S447)[phosAb] is detectable-but unchanged itpo xRagA(Q66L)
    *** cells: HEK293<xS6k1> in BMS
    *** unaffected by: xRagA(Q120L) [addition]
    *** source: 18604198-Fig-2c
  *** xS6k1[phosAb] phos(T444/S447)[phosAb] is detectable-but unchanged itpo xRagA(T21N)
    *** cells: HEK293<xS6k1> in BMS
    *** unaffected by: xRagC(S75N) [addition]
    *** source: 18604198-Fig-2c
  *** xS6k1[phosAb] phos(T444/S447)[phosAb] is detectable-but unchanged itpo xRagC
    *** cells: HEK293<xS6k1> in BMS
    *** unaffected by: xRagA [addition]
    *** source: 18604198-Fig-2c
  *** xS6k1[phosAb] phos(T444/S447)[phosAb] is detectable-but unchanged itpo xRagC(Q120L)
    *** cells: HEK293<xS6k1> in BMS
    *** unaffected by: xRagA(Q120L) [addition]
    *** source: 18604198-Fig-2c
  *** xS6k1[phosAb] phos(T444/S447)[phosAb] is detectable-but unchanged itpo xRagC(S75N)
    *** cells: HEK293<xS6k1> in BMS
    *** inhibited by: xRagA(T21N) [addition]
    *** source: 18604198-Fig-2c
  *** xS6k1[phosAb] phos(T444/S447)[phosAb] is increased itpo (xTsc1 + xTsc2)
    *** cells: HEK293 in BMS
    *** source: 12172553-Fig-1b
  *** xS6k1[phosAb] phos(T444/S447)[phosAb] is increased itpo Pik3c?(mnr)"CA"
    *** cells: HEK293<xS6k1> in BMLS
    *** bkg inhibited by: xS6k1(T252A) [substitution]
    *** source: 9632736-Fig-1b
  *** xS6k1[phosAb] phos(T444/S447)[phosAb] is increased itpo xAkt1
    *** cells: HEK293 in BMS
    *** source: 12172553-Fig-1b
  *** xS6k1[phosAb] phos(T444/S447)[phosAb] is increased itpo xHras(G12V)"CA"
    *** cells: HEK293 in BMS
    *** source: 12172553-Fig-1b
  *** S6k1[phosAb] phos(T444/S447)[phosAb] is increased itpo xRheb
    *** cells: HEK293T in BMLS
    *** source: 12842888-Fig-5
  *** xS6k1[tAb] copptby[WB] PP2a[Ab] is detectable
    *** cells: JURKATT in BMS
    *** source: 10200280-Fig-3b
  *** xS6k1[tAb] copptby[WB] xMtor[tAb] is detectable
    *** cells: HEK293<xMtor><xS6k1> in BMS
    *** unaffected by: xMtor(S2035A) [substitution]
    *** unaffected by: xMtor(S2035T) [substitution]
    *** unaffected by: xMtor(S2035R) [substitution]
    *** unaffected by: xMtor(S2035T/N2343K) [substitution]
    *** source: 9334222-Fig-2b
  *** xS6k1[tAb] copptby[WB] xRaptor[tAb] is detectable
    *** cells: HEK293<xRaptor><xS6k1> in BMS
    *** comment: IP was washed with high salt buffer without detergent
    *** unaffected by: xMtor [addition]
    *** source: 12150926-Fig-4b
  *** xS6k1[tAb] copptby[WB] xRheb[tAb] is undetectable
    *** cells: HEK293T<xRheb><xMlst8> in BMS
    *** source: 15854902-Fig-4b
  *** xS6k1[tAb]IP IVKA(Rps6)[32P-ATP] is decreased itpo (xTsc1 + xTsc2)
    *** cells: HEK293 in BMS
    *** source: 12172553-Fig-1a
  *** xS6k1[tAb]IP IVKA(Rps6)[32P-ATP] is detectable
    *** cells: CHO<xInsR><xS6k1> in BMLS
    *** inhibited by: xS6k1(47-525)"delNT" [substitution]
    *** unaffected by: xS6k1(47-525/T412E)"delNT" [substitution]
    *** source: 9632736-Fig-4b
  *** xS6k1[tAb]IP IVKA(Rps6)[32P-ATP] is detectable
    *** cells: HEK293 in BMS
    *** source: 11733037-Fig-3a
  *** xS6k1[tAb]IP IVKA(Rps6)[32P-ATP] is increased itpo (xPdpk1 + xPkcz)
    *** cells: HEK293E<xS6k1> in BMLS
    *** partially inhibited by: xS6k1(mnr)"F5adCT" [substitution]
    *** source: 12906785-Fig-4
  *** xS6k1[tAb]IP IVKA(Rps6)[32P-ATP] is increased itpo Pik3c?(mnr)"CA"
    *** cells: HEK293<xS6k1> in BMLS
    *** bkg inhibited by: xS6k1(T252A) [substitution]
    *** source: 9632736-Fig-1b
  *** xS6k1[tAb]IP IVKA(Rps6)[32P-ATP] is increased itpo xCdc42(G12V)"CA"
    *** cells: BHK in BMLS
    *** inhibited by: xCdc42(G12V/C189S)"prenylation-site-mut" [substitution]
    *** source: 8653792-Fig-1c
  *** xS6k1[tAb]IP IVKA(Rps6)[32P-ATP] is increased itpo xCdc42(G12V)"CA"
    *** cells: NIH3T3 in BMLS
    *** source: 8653792-Fig-1a
  *** xS6k1[tAb]IP IVKA(Rps6)[32P-ATP] is increased itpo xDbl
    *** cells: NIH3T3 in BMLS
    *** source: 8653792-Fig-2a
  *** xS6k1[tAb]IP IVKA(Rps6)[32P-ATP] is increased itpo xHras(G12V)"CA"
    *** cells: HEK293 in BMS
    *** source: 12172553-Fig-1a
  *** xS6k1[tAb]IP IVKA(Rps6)[32P-ATP] is increased itpo xPpp1r9b
    *** cells: COS7 in BMS
    *** source: 12531897(D)
  *** xS6k1[tAb]IP IVKA(Rps6)[32P-ATP] is increased itpo xPpp1r9b
    *** cells: NIH3T3 in BMS
    *** unaffected by: xRasGrf1 [addition]
    *** source: 12531897(D)
  *** xS6k1[tAb]IP IVKA(Rps6)[32P-ATP] is increased itpo xRac1
    *** cells: BHK in BMLS
    *** source: 8653792-Fig-1c
  *** xS6k1[tAb]IP IVKA(Rps6)[32P-ATP] is increased itpo xRac1(G12V)"CA"
    *** cells: BHK in BMLS
    *** source: 8653792-Fig-1c
  *** xS6k1[tAb]IP IVKA(Rps6)[32P-ATP] is increased itpo xRac1(G12V)"CA"
    *** cells: NIH3T3 in BMLS
    *** inhibited by: Wortmannin [addition]
    *** inhibited by: Rapamycin [addition]
    *** source: 8653792-Fig-1a
  *** xS6k1[tAb]IP IVKA(Rps6)[32P-ATP] is increased itpo xRac1(Q61L)"CA"
    *** cells: BHK in BMLS
    *** inhibited by: xRac1((41-192)/Q61L)"effector-region-mut" [substitution]
    *** source: 8653792-Fig-1c
  *** xS6k1[tAb]IP IVKA(Rps6)[32P-ATP] is increased itpo xRheb
    *** cells: HEK293E<xS6k1> in BMLS
    *** inhibited by: xRheb(C182S) [substitution]
    *** source: 12906785-Fig-7
  *** xS6k1[tAb]IP IVKA(Rps6)[32P-ATP] is increased itpo xRheb
    *** cells: HEK293E<xS6k1> in BMLS
    *** inhibited by: xS6k1(mnr)"F5adCT" [substitution]
    *** source: 12906785-Fig-4
  *** xS6k1[tAb]IP IVKA(Rps6)[32P-ATP] is increased itpo xRheb
    *** cells: HEK293E<xS6k1> in BMLS
    *** inhibited by: xTsc1 + xTsc2 [addition]
    *** source: 12906785-Fig-5b
  *** xS6k1[tAb]IP IVKA(Rps6)[32P-ATP] is increased itpo xRheb
    *** cells: HEK293E<xS6k1> in BMLS
    *** source: 12906785-Fig-1a
  *** xS6k1[tAb]IP IVKA(Rps6)[32P-ATP] is increased itpo xRheb
    *** cells: HEK293E<xS6k1> in BMLS
    *** source: 12906785-Fig-1b
  *** xS6k1[tAb]IP IVKA(Rps6)[32P-ATP] is increased itpo xRheb
    *** cells: HEK293E<xS6k1> in BSS "containing Glucose and AminoAcids"
    *** bkg inhibited by: Rapamycin [pretreatment]
    *** partially inhibited by: Wortmannin [pretreatment]
    *** source: 12906785-Fig-3
  *** xS6k1[tAb]IP IVKA(Rps6)[32P-ATP] is increased itpo xRheb
    *** cells: HEK293E<xS6k1> in BSS "containing Glucose"
    *** bkg inhibited by: Rapamycin [pretreatment]
    *** source: 12906785-Fig-5a
  *** xS6k1[tAb]IP IVKA(Rps6)[32P-ATP] is increased itpo xRheb
    *** cells: HEK293E<xS6k1> in BSS "containing Glucose"
    *** inhibited by: Rapamycin [pretreatment]
    *** partially inhibited by: Wortmannin [pretreatment]
    *** source: 12906785-Fig-3
  *** xS6k1[tAb]IP IVKA(Rps6)[32P-ATP] is increased itpo xRheb
    *** cells: HEK293E<xS6k1> in BSS "containing Glucose"
    *** inhibited by: xTsc1 + xTsc2 [addition]
    *** source: 12906785-Fig-5a
  *** xS6k1[tAb]IP IVKA(Rps6)[32P-ATP] is increased itpo xTiam1
    *** cells: NIH3T3 in BMS
    *** inhibited by: xRac1(T17N)"DN" [addition]
    *** enhanced by: xPpp1r9b [addition]
    *** source: 12531897(D)
  *** xS6k1[tAb]IP IVKA(Rps6)[32P-ATP] is unchanged itpo xRhoa(G12V)"CA"
    *** cells: NIH3T3 in BMLS
    *** source: 8653792-Fig-1a
  *** xS6k1[tAb]IP IVKA(S6peptide)[32P-ATP] is detectable
    *** cells: COS7<xS6k1> in BMLS
    *** enhanced by: xS6k1(T389E) [substitution]
    *** inhibited by: xS6k1(R121A) [substitution]
    *** inhibited by: xS6k1(T389E/R121A) [substitution]
    *** source: 12374740-Fig-8a
  *** xS6k1[tAb]IP phos(T229)[phosAb] is detectable
    *** cells: COS7<xS6k1> in BMLS
    *** unaffected by: xS6k1(T389E) [substitution]
    *** unaffected by: xS6k1(R121A) [substitution]
    *** unaffected by: xS6k1(T389E/R121A) [substitution]
    *** source: 12374740-Fig-8b
  *** xS6k1[tAb]IP phos(T389)[phosAb] is detectable
    *** cells: COS7<xS6k1> in BMLS
    *** inhibited by: xS6k1(R121A) [substitution]
    *** source: 12374740-Fig-8b
  *** xS6k1[tAb]IP phos(T412)[phosAb] is decreased itpo (xTsc1 + xTsc2)
    *** cells: HEK293 in BMS
    *** source: 12172553-Fig-7b
  *** xS6k1[tAb]IP phos(T412)[phosAb] is decreased itpo xAmpka1
    *** cells: HEK293<xS6k1> in BMS
    *** reqs: Tsc2 [RNAi]
    *** source: 14651849-Fig-3c
  *** xS6k1[tAb]IP phos(T412)[phosAb] is decreased itpo xAmpka2
    *** cells: HEK293<xS6k1> in BMS
    *** reqs: Tsc2 [RNAi]
    *** source: 14651849-Fig-3c
  *** xS6k1[tAb]IP phos(T412)[phosAb] is decreased itpo xDdit4
    *** cells: HEK293<xS6k1> in BMS
    *** reversed by: xDdit4(mnr)"dC" [substitution]
    *** source: 15545625-Fig-7a
  *** xS6k1[tAb]IP phos(T412)[phosAb] is decreased itpo xDdit4
    *** cells: HELA<xS6k1> in BMS
    *** reqs: Tsc2 [RNAi]
    *** source: 15545625-Fig-7b
  *** xS6k1[tAb]IP phos(T412)[phosAb] is decreased itpo xDdit4
    *** cells: HELA<xS6k1> in BMS
    *** reversed by: xDdit4(mnr)"dC" [substitution]
    *** enhanced by: xDdit4l [addition]
    *** source: 15545625-Fig-7b
  *** xS6k1[tAb]IP phos(T412)[phosAb] is decreased itpo xDdit4
    *** cells: mEFs<Tsc2~null><xTsc2> in BMS
    *** reqs: xTsc2 [omission]
    *** reversed by: xTsc2(S939A/T1462A) [substitution]
    *** source: 18198340-Fig-5d
  *** xS6k1[tAb]IP phos(T412)[phosAb] is decreased itpo xDdit4
    *** cells: mEFs<xS6k1> in BMS
    *** reqs: Tsc2 [KO]
    *** source: 15988001-Fig-4a
  *** xS6k1[tAb]IP phos(T412)[phosAb] is decreased itpo xDdit4
    *** cells: mEFs<xS6k1> in BMS
    *** reversed by: xRheb [addition]
    *** source: 15988001-Fig-4b
  *** xS6k1[tAb]IP phos(T412)[phosAb] is decreased itpo xDdit4
    *** cells: mEFs<xS6k1> in BMS
    *** unaffected by: xDdit4(del(96-156))"dC" [substitution]
    *** source: 15988001-Fig-4a
  *** xS6k1[tAb]IP phos(T412)[phosAb] is decreased itpo xDdit4l
    *** cells: HELA<xS6k1> in BMS
    *** enhanced by: xDdit4 [addition]
    *** source: 15545625-Fig-7b
  *** xS6k1[tAb]IP phos(T412)[phosAb] is decreased itpo xDdit4l
    *** cells: HELA<xS6k1> in BMS
    *** reqs: Tsc2 [RNAi]
    *** source: 15545625-Fig-7b
  *** xS6k1[tAb]IP phos(T412)[phosAb] is decreased itpo xDeptor
    *** cells: HELA<xS6k1> in BMS
    *** enhanced by: xDeptor(mnr)"DEP-DEP" [substitution]
    *** unaffected by: xDeptor(mnr)"PDZ" [substitution]
    *** source: 19446321-Fig-5b
  *** xS6k1[tAb]IP phos(T412)[phosAb] is decreased itpo xDeptor
    *** cells: mEFs<Tp53~null><xS6k1> in BMS
    *** does not req: Rictor [KO]
    *** source: 19446321-Fig-5b
  *** xS6k1[tAb]IP phos(T412)[phosAb] is decreased itpo xDeptor
    *** cells: mEFs<Tp53~null><xS6k1> in BMS
    *** does not req: Tsc2 [KO]
    *** source: 19446321-Fig-5b
  *** xS6k1[tAb]IP phos(T412)[phosAb] is decreased itpo xDeptor
    *** cells: mEFs<Tp53~null><xS6k1> in BMS
    *** unaffected by: xDeptor(dig)"13ST/A" [substitution]
    *** source: 19446321-Fig-5b
  *** xS6k1[tAb]IP phos(T412)[phosAb] is decreased itpo xPras40
    *** cells: mEFs<Tp53~null><xS6k1> in BMS
    *** does not req: Rictor [KO]
    *** source: 19446321-Fig-5b
  *** xS6k1[tAb]IP phos(T412)[phosAb] is decreased itpo xPras40
    *** cells: mEFs<Tp53~null><xS6k1> in BMS
    *** does not req: Tsc2 [KO]
    *** source: 19446321-Fig-5b
  *** xS6k1[tAb]IP phos(T412)[phosAb] is decreased itpo xPras40
    *** cells: mEFs<Tp53~null><xS6k1> in BMS
    *** source: 19446321-Fig-5b
  *** xS6k1[tAb]IP phos(T412)[phosAb] is decreased itpo xRab5a(Q79L)"CA"
    *** cells: mEFs<Tsc2~null><xS6k1> in BMLS "AminoAcid deprived"
    *** source: 20053679-Fig-2c
  *** xS6k1[tAb]IP phos(T412)[phosAb] is decreased itpo xTsc2
    *** cells: mEFs<Tsc2~null> in BMLS
    *** source: 17693255-Fig-S3a
  *** xS6k1[tAb]IP phos(T412)[phosAb] is detectable
    *** cells: DROSOPHILAS2 in BMS
    *** reqs: Rheb [RNAi]
    *** source: 12766776(D)
  *** xS6k1[tAb]IP phos(T412)[phosAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 11733037-Fig-3a
  *** xS6k1[tAb]IP phos(T412)[phosAb] is detectable
    *** cells: HEK293T<xS6k1><xRagB(Q99L)"GTP"> in BMS
    *** unaffected by: AA-deprivation [pretreatment]
    *** inhibited by: Rapamycin [pretreatment]
    *** unaffected by: 2DOG [pretreatment]
    *** partially inhibited by: H2O2 [pretreatment]
    *** partially inhibited by: Valinomycin [pretreatment]
    *** source: 18497260-Fig-S4
  *** xS6k1[tAb]IP phos(T412)[phosAb] is detectable
    *** cells: HEK293T<xS6k1><xRap2a> in BMS
    *** inhibited by: AA-deprivation [pretreatment]
    *** inhibited by: Rapamycin [pretreatment]
    *** unaffected by: 2DOG [pretreatment]
    *** inhibited by: H2O2 [pretreatment]
    *** inhibited by: Valinomycin [pretreatment]
    *** source: 18497260-Fig-S4
  *** xS6k1[tAb]IP phos(T412)[phosAb] is detectable
    *** cells: mEFs<Tsc1~null><xS6k1> in BMLS
    *** partially inhibited by: xTsc1 [addition]
    *** source: 17693255-Fig-5a
  *** xS6k1[tAb]IP phos(T412)[phosAb] is detectable
    *** cells: mEFs<Tsc1~null><xTsc1><xS6k1> in BMLS
    *** partially inhibited by: xTsc1(S487A) [substitution]
    *** enhanced by: xTsc1(S487D) [substitution]
    *** partially inhibited by: xTsc1(S511A) [substitution]
    *** enhanced by: xTsc1(S511D) [substitution]
    *** partially inhibited by: xTsc1(S487A/S511A) [substitution]
    *** enhanced by: xTsc1(S487D/S511D) [substitution]
    *** source: 17693255-Fig-5a
  *** xS6k1[tAb]IP phos(T412)[phosAb] is increased itao Tsc2 [RNAi]
    *** cells: DROSOPHILAS2 in BMS
    *** source: 12766776(D)
  *** xS6k1[tAb]IP phos(T412)[phosAb] is increased itpo (xRagB + xRagC)
    *** cells: HEK293T<xS6k1> in BMS "AminoAcids-deprived"
    *** enhanced by: xRagB(Q99L)"GTP" + xRagC(S75L)"GDP" [substitution]
    *** inhibited by: xRagB(T54L)"GDP" + xRagC(Q120L)"GTP" [substitution]
    *** source: 18497260-Fig-2b
  *** xS6k1[tAb]IP phos(T412)[phosAb] is increased itpo (xRagB + xRagC)
    *** cells: HEK293T<xS6k1> in BMS "Leucine-deprived"
    *** enhanced by: xRagB(Q99L)"GTP" + xRagC(S75L)"GDP" [substitution]
    *** inhibited by: xRagB(T54L)"GDP" + xRagC(Q120L)"GTP" [substitution]
    *** source: 18497260-Fig-2a
  *** xS6k1[tAb]IP phos(T412)[phosAb] is increased itpo (xRagB(Q99L)"GTP" + xRagC(S75L)"GDP")
    *** cells: HEK293T<xS6k1> in BMLS "Leucine-deprived"
    *** unaffected by: CHX [addition]
    *** source: 18497260-Fig-S5
  *** xS6k1[tAb]IP phos(T412)[phosAb] is increased itpo xRagB(Q99L)"GTP"
    *** cells: HEK293T<xS6k1> in BMS
    *** unaffected by: AA-deprivation [pretreatment]
    *** inhibited by: Rapamycin [pretreatment]
    *** unaffected by: 2DOG [pretreatment]
    *** partially inhibited by: H2O2 [pretreatment]
    *** partially inhibited by: Valinomycin [pretreatment]
    *** source: 18497260-Fig-S4
  *** xS6k1[tAb]IP phos(T412)[phosAb] is increased itpo xRheb
    *** cells: HEK293E<xS6k1> in BMLS
    *** source: 18497260-Fig-2c
  *** xS6k1[tAb]IP phos(T412)[phosAb] is increased itpo xRheb
    *** cells: HEK293E<xS6k1> in BMLS
    *** unaffected by: xRab5a(Q79L)"CA" [addition]
    *** source: 20053679-Fig-2a
  *** xS6k1[tAb]IP phos(T412)[phosAb] is increased itpo xRheb
    *** cells: HEK293T<xS6k1> in BMS "AminoAcids-deprived"
    *** source: 18497260-Fig-2b
  *** xS6k1[tAb]IP phos(T412)[phosAb] is increased itpo xRheb
    *** cells: HEK293T<xS6k1> in BMS "Leucine-deprived"
    *** source: 18497260-Fig-2a
  *** xS6k1[tAb]IP phos(T412)[phosAb] is increased itpo xYwhab
    *** cells: HEK293<xS6k1> in BMS
    *** source: 12364343-Fig-4e
  *** xS6k1[tAb]IP phos(T412)[phosAb] is unchanged itpo (xRagB(Q99L)"GTP" + xRagC(S75L)"GDP")
    *** cells: HEK293E<xS6k1> in BMLS
    *** source: 18497260-Fig-2c
  *** xS6k1[tAb]IP phos(T412)[phosAb] is unchanged itpo xDdit4l
    *** cells: HEK293<xS6k1> in BMS
    *** source: 15545625-Fig-7a
  *** xS6k1[tAb]IP phos(T412)[phosAb] is unchanged itpo xRheb
    *** cells: mEFs<xS6k1> in BMS
    *** source: 15988001-Fig-4b
*** S6k2--
  *** xS6k2[phosAb] phos(T389)[phosAb] is increased itpo xRheb
    *** cells: HELA<xS6k2> in BMLS
    *** source: 12820960-Fig-2d
  *** xS6k2[tAb]IP IVKA(Rps6)[32P-ATP] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xS6k1(K112R) [substitution]
    *** inhibited by: xS6k1(T241A) [substitution]
    *** partially inhibited by: xS6k1(S383G) [substitution]
    *** inhibited by: xS6k1(T401A) [substitution]
    *** enhanced by: xS6k1(T401E) [substitution]
    *** source: 11733037-Fig-3a
  *** xS6k2[tAb]IP IVKA(Rps6)[32P-ATP] is detectable
    *** cells: HEK293 in BMS
    *** source: 11733037-Fig-3b
  *** xS6k2[tAb]IP phos(T386)[phosAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 11733037-Fig-3b
  *** S6ks[Ab] phos[WBMS] is detectable
    *** cells: PC12<xGab1> in BMLS
    *** unaffected by: PD98059 [addition]
    *** inhibited by: LY294002 [addition]
    *** source: 10601297-Fig-9c
  *** S6ks[Ab] prot-exp[WB] is increased itpo xGab1
    *** cells: PC12 in BMLS
    *** source: 10601297-Fig-4a
  *** S6ks[Ab]IP IVKA(peptide)[32P-ATP] is detectable
    *** cells: mESCs in BMLS
    *** reqs: Pdpk1 [KO]
    *** source: 12912918(D)
  *** S6ks[Ab]IP phos(T389)[phosAb] is detectable
    *** cells: mESCs in BMLS
    *** reqs: Pdpk1 [KO]
    *** inhibited by: kPdpk1(L155E) [substitution]
    *** source: 12912918-Fig-4a
  *** S6ks[phosAb] phos(FTYV)[phosAb] is detectable
    *** cells: HELA<xTbk1> in BMS
    *** reqs: Mtor [RNAi]
    *** does not req: Rictor [RNAi]
    *** source: 21464307-Fig-S5a
  *** S6ks[phosAb] phos(FTYV)[phosAb] is detectable
    *** cells: HELA<xTbk1> in BMS
    *** unaffected by: xTbk1(mnr)"KD" [substitution]
    *** source: 21464307-Fig-S5a
  *** S100a6-gene mRNA[MicroArray] is detectable
    *** cells: THP1 in BMS
    *** reqs: Ampka1 [RNAi]
    *** source: 22833096-Table-S2a
  *** Sap130[Ab] snaggedby[WB] rMyc[GST] is detectable
    *** cells: HELA in BMS "nuclear-extracts"
    *** source: 12660246-Fig-2a
*** Sara--
  *** xSara(mnr)"SBD"[tAb] copptby[WB] xSmad3[tAb] is detectable
    *** cells: HEK293T<xPmlc> in BMS
    *** reqs: xPmlc [omission]
    *** source: 15356634-Fig-2f
  *** rSara[35S] boundby[WB] rSmad1[GST] is detectable
    *** cells: none
    *** source: 9865696-Fig-2b
  *** rSara[35S] boundby[WB] rSmad4[GST] is undetectable
    *** cells: none
    *** source: 9865696-Fig-2b
  *** Sara[Ab] colocwith[IHC] Eea1[Ab] is detectable
    *** cells: HELA in BMS
    *** source: 12356868-Fig-1
  *** Sara[Ab] copptby[WB] Smad23s[Ab] is detectable
    *** cells: mEFs in BMS
    *** reqs: Pml [KO]
    *** source: 15356634-Fig-2c
  *** Sara[Ab] copptby[WB] Smad23s[Ab] is detectable
    *** cells: mEFs in BMS
    *** reqs: Pml [KO]
    *** source: 15356634-Fig-2h
  *** Sara[Ab] copptby[WB] Smad23s[Ab] is detectable
    *** cells: mEFs<Pml~null><xPmlc> in BMS
    *** reqs: xPmlc [omission]
    *** source: 15356634-Fig-2h
  *** Sara[Ab] copptby[WB] Sptbn1[Ab] is undetectable
    *** cells: HEPG2 in BMS
    *** unaffected by: TgfbR1 (1 hr) [stim]
    *** source: 12543979-Fig-S2e
  *** Sara[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: MV1LU in BMS
    *** source: 9865696-Fig-4a
  *** xSara[tAb] colocwith[IHC] Smad23s[Ab] is detectable
    *** cells: HELA in BMS
    *** source: 12356868-Fig-8c
  *** xSara[tAb] copptby[WB] xBmpR1b[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 17272273-Fig-4d
  *** xSara[tAb] copptby[WB] xPmlc[tAb] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: Tgfb1 (1 hr) [stim]
    *** source: 15356634-Fig-2d
  *** xSara[tAb] copptby[WB] xSmad2[tAb] is detectable
    *** cells: COS1 in BMS
    *** unaffected by: xSmad4 [addition]
    *** source: 9865696-Fig-3c
  *** xSara[tAb] copptby[WB] xSmad2[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 17272273-Fig-4a
  *** xSara[tAb] copptby[WB] xSmad2[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 17272273-Fig-4c
  *** xSara[tAb] copptby[WB] xSmad2[tAb] is increased itpo xHgs
    *** cells: HEK293T<xAcvR2><xAcvR1b> in BMS
    *** source: 11094085(D)
  *** xSara[tAb] copptby[WB] xSmad4[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 17272273-Fig-4a
  *** xSara[tAb] locatedin(cytoplasm)[IHC] is detectable
    *** cells: MV1LU in BMS
    *** source: 9865696-Fig-4a
  *** xSara[tAb]IP phos[32Pi] is detectable
    *** cells: COS1 in BMS
    *** unaffected by: xTgfbR1 [addition]
    *** unaffected by: xTgfbR1(T204D)"CA" [addition]
    *** source: 9865696-Fig-3a
*** Sart3--
  *** Sart3[MS] copptby[WB] Sin1[Ab] is detectable
    *** cells: HELA in BMS
    *** source: 16962653-Fig-1a
  *** xSenp2(mnr)"CIA"[tAb] copptby[WB] xElk1[Ab] is undetectable
    *** cells: HEK293T<xSenp2(mnr)"CIA"> in BMS
    *** source: 20337593-Fig-2b
  *** xSenp2(mnr)"CIA"[tAb] snaggedby[WB] rElk1(205-428)[GST] is undetectable
    *** cells: HEK293T<xSenp2(mnr)"CIA"> in BMS
    *** source: 20337593-Fig-2b
  *** xSenp3(mnr)"CIA"[tAb] snaggedby[WB] rElk1(205-428)[GST] is undetectable
    *** cells: HEK293T<xSenp3(mnr)"CIA"> in BMS
    *** source: 20337593-Fig-2b
  *** Sfn[Ab] locatedin(cytoplasm)[IHC] is detectable
    *** cells: U2OS in BMS
    *** source: 11864996-Fig-1a
** Sgk1--
  *** xSgk1(61-431)[phosAb] phos(T256)[phosAb] is detectable
    *** cells: COS7<xAkt1><xPdpk1> in BMLS "treated with Serum for 10 min"
    *** inhibited by: xPdpk1(S241A) [substitution]
    *** unaffected by: xPdpk1(R238E) [substitution]
    *** enhanced by: xPdpk1(V243P) [substitution]
    *** source: 12177059-Fig-4c
  *** xSgk1[Ab]IP IVKA(peptide)[32P-ATP] is increased itpo xRac1(mnr)"CA"
    *** cells: MDCK in BMS
    *** inhibited by: Wortmannin [addition]
    *** source: 11956329(D)
  *** Sgk1[phosAb] phos(T256)[phosAb] is increased itao Tsc2 [RNAi]
    *** cells: WM35 in BMS
    *** source: 18570873-Fig-7e
  *** xSgk1[tAb] copptby[WB] xBraf[GST] is detectable
    *** cells: HEK293 in BMS
    *** source: 11410590-Fig-4a
  *** xSgk1[tAb]IP IVKA(peptide)[32P-ATP] is detectable
    *** cells: HEK293<xSgk1> in BMS
    *** inhibited by: PI103 [pretreatment]
    *** unaffected by: Rapamycin [pretreatment]
    *** source: 18925875-Fig-5a
  *** xSgk1[tAb]IP IVKA(peptide)[32P-ATP] is detectable
    *** cells: mESCs in BMLS
    *** reqs: Pdpk1 [KO]
    *** inhibited by: kPdpk1(L155E) [substitution]
    *** source: 12912918-Fig-6a
  *** xSgk1[tAb]IP phos(S422)[phosAb] is detectable
    *** cells: mESCs in BMLS
    *** does not req: Pdpk1 [KO]
    *** partially inhibited by: Wortmannin [addition] no-bkg-control
    *** source: 12912918-Fig-6a
  *** xSgk1[tAb]IP phos(S422)[phosAb] is detectable
    *** cells: mESCs in BMLS
    *** does not req: Pdpk1 [KO]
    *** unaffected by: kPdpk1(L155E) [substitution]
    *** source: 12912918-Fig-6a
*** Sh2d3c--
  *** xSh2d3c[Ab]IP Yphos[pYAb] is increased itpo xEpha2
    *** cells: HEK293 in BMS
    *** source: 15272013-Fig-1a
  *** xSh2d3c[Ab]IP Yphos[pYAb] is increased itpo xEphb2
    *** cells: COS in BMS
    *** partially inhibited by: xSh2d3c(Y635E) [substitution]
    *** source: 15272013-Fig-5d
  *** xSh2d3c[Ab]IP Yphos[pYAb] is increased itpo xEphb2
    *** cells: HEK293 in BMS
    *** source: 15272013-Fig-1a
  *** Sh2d3c[Ab]IP Yphos[pYAb] is increased itpo xEphb2
    *** cells: HEK293 in BMS
    *** source: 15272013-Fig-1c
  *** xSh2d3c[tAb] copptby[WB] xBcar1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xCrk [addition]
    *** source: 12432078-Fig-6
  *** xSh2d3c[tAb] copptby[WB] xCrk[tAb] is detectable
    *** cells: HEK293T<xBcar1> in BMS
    *** reqs: xBcar1 [omission]
    *** source: 12432078-Fig-6
*** Shc1--
  *** Shc1[Ab] copptby[WB] xIL2Rb[Ab] is detectable
    *** cells: 32D<IL2Rb~null><xIL2Rb> in BMS "IL3-deprived" "treated with IL2 for 15 min"
    *** inhibited by: xIL2Rb(Y364F/Y381F/Y383F/Y387F/Y418F/Y536F)"FFFFFF" [substitution]
    *** inhibited by: xIL2Rb(Y364F/Y418F/Y536F)"FYYYFF" [substitution]
    *** unaffected by: xIL2Rb(Y418F/Y536F)"YYYYFF" [substitution]
    *** inhibited by: xIL2Rb(Y364F/Y381F/Y383F/Y387F)"FFFFYY" [substitution]
    *** source: 8700888-Fig-3a
  *** xShc1[Ab] snaggedby[WB] rGab1[GST] is detectable
    *** cells: HEK293<xFgfR1> in BMS
    *** reqs: xFgfR1 [omission]
    *** inhibited by: xFgfR1(mnr)"KD" [substitution]
    *** source: 11353842-Fig-2b
  *** Shc1[Ab]IP Yphos[pYAb] is increased itpo xFak2
    *** cells: HEK293T in BMS
    *** inhibited by: xFak2(Y402F) [substitution]
    *** unaffected by: xFak2(Y881F) [substitution]
    *** inhibited by: xFak2(mnr)"KD" [substitution]
    *** source: 10329689-Fig-2a
  *** Shc1[Ab]IP Yphos[pYAb] is unchanged itpo xRala(Q72L)"CA"
    *** cells: HEK293 in BMLS
    *** source: 10675331-Fig-5b
  *** Shc1p46[Ab] copptby[WB] Grb2[Ab] is detectable
    *** cells: 16E6P in BMS "Egf deprived"
    *** enhanced by: Egf (10 min) [stim]
    *** source: 8662998-Fig-4
  *** rShc1p52[35S] boundby[WB] rTgfbR1(mnr)"cyto-domain"[GST] is detectable
    *** cells: none
    *** unaffected by: rTgfbR1(mnr/K230R)"KD-cyto-domain" [substitution]
    *** source: 17673906-Fig-4e
  *** rShc1p52[35S] boundby[WB] rTgfbR2(mnr)"cyto-domain"[GST] is detectable
    *** cells: none
    *** unaffected by: rTgfbR2(mnr/K277R)"KD-cyto-domain" [substitution]
    *** source: 17673906-Fig-4e
  *** Shc1p52[Ab] copptby[WB] Grb2[Ab] is detectable
    *** cells: 16E6P in BMS "Egf deprived"
    *** unaffected by: Egf (10 min) [stim]
    *** source: 8662998-Fig-4
  *** xShc1p66[Ab] copptby[WB] xGrb2[Ab] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xShc1p66(Y349F/Y350F/Y427F) [substitution]
    *** source: 16520382-Fig-2d
  *** xShc1p66[Ab] copptby[WB] xGrb2[Ab] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: xShc1p66(P47A/P50A) [substitution]
    *** source: 16520382-Fig-2e
  *** Shc1p66[Ab]IP Yphos[pYAb] is detectable
    *** cells: SWISS3T3 in BMS
    *** inhibited by: xShc1(mnr)"CH1/SH2-domains" [addition]
    *** inhibited by: xShc1(mnr)"PTP/CH1-domains" [addition]
    *** source: 17673906-Fig-8a
  *** xShc1p66[tAb] copptby[WB] xTgfbR1(mnr)"cyto-domain"[tAb] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: xShc1(mnr)"PTP-domain" [substitution]
    *** inhibited by: xShc1(mnr)"CH1/SH2-domains" [substitution]
    *** unaffected by: xShc1(mnr)"PTP/CH1-domains" [substitution]
    *** inhibited by: xShc1(mnr)"CH1-domain" [substitution]
    *** source: 17673906-Fig-5a
  *** xShc1p66[tAb] copptby[WB] xTgfbR1[tAb] is detectable
    *** cells: COS in BMS
    *** source: 17673906-Fig-4a
  *** xShc1p66[tAb] copptby[WB] xTgfbR2(mnr)"cyto-domain"[tAb] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: xShc1(mnr)"PTP-domain" [substitution]
    *** inhibited by: xShc1(mnr)"CH1/SH2-domains" [substitution]
    *** unaffected by: xShc1(mnr)"PTP/CH1-domains" [substitution]
    *** inhibited by: xShc1(mnr)"CH1-domain" [substitution]
    *** source: 17673906-Fig-5b
  *** xShc1p66[tAb] copptby[WB] xTgfbR2[tAb] is detectable
    *** cells: COS in BMS
    *** source: 17673906-Fig-4a
*** Shoc2--
  *** Shoc2[Ab] copptby[WB] xHras(G12V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 16630891-Fig-1b
  *** Shoc2[Ab] copptby[WB] xHras[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 16630891-Fig-1b
  *** Shoc2[Ab] copptby[WB] xKras(G12V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 16630891-Fig-1b
  *** Shoc2[Ab] copptby[WB] xKras[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 16630891-Fig-1b
  *** Shoc2[Ab] copptby[WB] xNras(G12V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 16630891-Fig-1b,1f
  *** Shoc2[Ab] copptby[WB] xNras[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 16630891-Fig-1b,1f
  *** Shoc2[Ab] copptby[WB] xRap1a(G12V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 16630891-Fig-1b
  *** Shoc2[Ab] copptby[WB] xRras(G38V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 16630891-Fig-1b
  *** Shoc2[Ab] copptby[WB] xRras[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 16630891-Fig-1b
  *** Shoc2[Ab] copptby[WB] xRras2(G13V)"CA"[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 16630891-Fig-1b
  *** Shoc2[Ab] copptby[WB] xRras2[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 16630891-Fig-1b
  *** rShoc2[tAb] boundby[WB] rHras{GTPgS}[GST] is detectable
    *** cells: none
    *** unaffected by: rHras{GDPbS} [substitution]
    *** comment: much less Shoc2 binds to Hras than to Kras or Nras
    *** source: 9674433-Fig-5b
  *** rShoc2[tAb] boundby[WB] rKras{GTPgS}[GST] is detectable
    *** cells: none
    *** unaffected by: rKras{GDPbS} [substitution]
    *** source: 9674433-Fig-5b
  *** rShoc2[tAb] boundby[WB] rNras{GTPgS}[GST] is detectable
    *** cells: none
    *** unaffected by: rNras{GDPbS} [substitution]
    *** source: 9674433-Fig-5b
  *** xShoc2[tAb] copptby[WB] xKras(G12V)"CA"[Ab] is detectable
    *** cells: HEK293 in BMLS
    *** source: 10783161-Fig-3b
  *** xShoc2[tAb] copptby[WB] xNras(G12V)"CA"[tAb] is undetectable
    *** cells: HEK293T<xRaf1> in BMS
    *** source: 16630891-Fig-3b
  *** xShoc2[tAb] copptby[WB] xRaf1[tAb] is detectable
    *** cells: HEK293 in BMLS
    *** source: 10783161-Fig-3c,3d
  *** xShoc2[tAb] snaggedby[WB] rKras(G12V)"CA"[GST] is detectable
    *** cells: HEK293 in BMLS
    *** enhanced by: xRaf1 [addition]
    *** source: 10783161-Fig-4c
*** Shp2--
  *** xShp2(C459S)[tAb] snaggedby[WB] rGab2{phos}[GST] is detectable
    *** cells: KIT225 in BMS
    *** comment: rGab2 was phosphorylated in coli by Ephb1 co-expression
    *** partially inhibited by: rGab2(Y614F){phos} [substitution]
    *** partially inhibited by: rGab2(Y643F){phos} [substitution]
    *** inhibited by: rGab2(Y614F/Y643F){phos} [substitution]
    *** source: 15170389-Fig-1d
  *** xShp2(E76A)[tAb] snaggedby[WB] rGab2{phos}[GST] is detectable
    *** cells: KIT225 in BMS
    *** comment: rGab2 was phosphorylated in coli by Ephb1 co-expression
    *** partially inhibited by: rGab2(Y614F){phos} [substitution]
    *** partially inhibited by: rGab2(Y643F){phos} [substitution]
    *** inhibited by: rGab2(Y614F/Y643F){phos} [substitution]
    *** source: 15170389-Fig-1d
  *** Shp2[Ab] copptby[WB] Jak1[Ab] is detectable
    *** cells: hPBTCs in BMS
    *** unaffected by: IL2 (5 min) [stim]
    *** source: 9590209-Fig-2d
  *** Shp2[Ab] copptby[WB] Jak1[Ab] is detectable
    *** cells: NK33 in BMS "treated with IL2 for 5 min"
    *** source: 9590209-Fig-2a
  *** Shp2[Ab] copptby[WB] Jak3[Ab] is detectable
    *** cells: hPBTCs in BMS
    *** unaffected by: IL2 (5 min) [stim]
    *** source: 9590209-Fig-2c
  *** Shp2[Ab] copptby[WB] Jak3[Ab] is detectable
    *** cells: NK33 in BMS
    *** unaffected by: IL2 (5 min) [stim]
    *** source: 9590209-Fig-2a
  *** Shp2[Ab] copptby[WB] Pik3rs[Ab] is undetectable
    *** cells: RAMOS in BMLS "treated with IL4 for 1 min"
    *** source: 9065461-Fig-4b
  *** Shp2[Ab] copptby[WB] Pxn[Ab] is decreased itpo xGab1(Y627F/Y659F)
    *** cells: MDAMB468 in BMLS
    *** source: 14665621-Fig-4b
  *** Shp2[Ab] copptby[WB] Pxn[Ab] is decreased itpo xGab1(Y627F/Y659F)
    *** cells: MDAMB468 in BMLS
    *** source: 14665621-Fig-7c
  *** Shp2[Ab] copptby[WB] xFrs2[Ab] is increased itpo xFgfR1
    *** cells: HEK293<xFrs2> in BMS
    *** unaffected by: xFrs2(Y196F/Y306F/Y349F/Y392F) [substitution]
    *** inhibited by: xFrs2(Y436F) [substitution]
    *** inhibited by: xFrs2(Y196F/Y306F/Y349F/Y392F/Y436F) [substitution]
    *** source: 9632781-Fig-2a
  *** Shp2[Ab] copptby[WB] xGab1[Ab] is detectable
    *** cells: HEK293<xGab2><xPik3r1> in BMS "treated with Hgf + PAO for tnr"
    *** unaffected by: xGab1(116-694) [substitution]
    *** unaffected by: xGab1(del(242-411))"dCrk" [substitution]
    *** unaffected by: xGab1(Y448F/Y473F/Y590F)"dPi3k" [substitution]
    *** inhibited by: xGab1(Y682F)"dShp2" [substitution]
    *** unaffected by: xGab1(450-694) [substitution]
    *** unaffected by: xGab1((450-694)/Y473F/Y590F) [substitution]
    *** source: 10871282-Fig-4b
  *** Shp2[Ab] copptby[WB] xGab1[tAb] is detectable
    *** cells: MDCK<xGab1> in BMLS
    *** source: 12058075-Fig-2b
  *** Shp2[Ab] copptby[WB] xGab2[tAb] is detectable
    *** cells: MDCK<xGab2> in BMLS
    *** source: 12058075-Fig-2b
  *** Shp2[Ab] copptby[WB] xSocs3[Ab] is detectable
    *** cells: COS7 in BMS
    *** source: 10777583-Fig-6
  *** xShp2[Ab] snaggedby[WB] rGab1[GST] is detectable
    *** cells: HEK293<xFgfR1> in BMS
    *** inhibited by: xFgfR1(mnr)"KD" [substitution]
    *** source: 11353842-Fig-2c
  *** Shp2[Ab] snaggedby[WB] rGab2{phos}[GST] is detectable
    *** cells: KIT225 in BMS
    *** comment: rGab2 was phosphorylated in coli by Ephb1 co-expression
    *** partially inhibited by: rGab2(Y614F){phos} [substitution]
    *** partially inhibited by: rGab2(Y643F){phos} [substitution]
    *** inhibited by: rGab2(Y614F/Y643F){phos} [substitution]
    *** inhibited by: rGab2 [substitution]
    *** source: 15170389-Fig-1a
  *** Shp2[Ab]IP Yphos[pYAb] is detectable
    *** cells: MM1S<xHck> in BMLS
    *** inhibited by: xHck(K269E) [substitution]
    *** source: 15010462-Fig-6a
  *** xShp2[tAb] copptby[WB] xGab1[tAb] is detectable
    *** cells: HEK293T<xJak1> in BMS
    *** source: 9632795-Fig-2
  *** xShp2[tAb] copptby[WB] xLmo4(21-60)"Lim1S"[GST] is detectable
    *** cells: COS1 in BMS
    *** unaffected by: xLmo4(86-125)"Lim2S" [substitution]
    *** inhibited by: xLmo4(79-165)"Lim2L" [substitution]
    *** source: 15677447-Fig-5b
  *** xShp2[tAb] copptby[WB] xPik3rs[tAb] is detectable
    *** cells: HEK293T<xJak1><xGab1> in BMS
    *** reqs: xGab1 [omission]
    *** source: 9632795-Fig-2
  *** xShp2[tAb] snaggedby[WB] rMyc(51-66)[agarose] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15103331-Fig-3a
*** Siah1--
  *** Siah1[Ab] copptby[WB] Posh[Ab] is detectable
    *** cells: HEK293 in BMS "treated with Camptothecin"
    *** source: 16230351-Fig-1b
  *** xSiah1[tAb] copptby[WB] xPosh[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 16230351-Fig-1b
  *** xSiah1[tAb] prot-exp[WB] is increased itpo xMlk1
    *** cells: U2OS in BMS
    *** inhibited by: xJnk1(mnr)"DN" [addition]
    *** reqs: Posh [RNAi]
    *** source: 16230351-Fig-4g
  *** xSiah1[tAb] prot-exp[WB] is increased itpo xMlk2
    *** cells: U2OS in BMS
    *** inhibited by: CEP1347 [addition]
    *** source: 16230351-Fig-4d
  *** xSiah1[tAb] prot-exp[WB] is increased itpo xMlk3
    *** cells: U2OS in BMS
    *** inhibited by: CEP1347 [addition]
    *** inhibited by: SP600125 [addition]
    *** inhibited by: xMkk7(mnr)"DN" [addition]
    *** source: 16230351-Fig-4c,4f
  *** xSiah1[tAb] prot-exp[WB] is increased itpo xPosh
    *** cells: U2OS in BMS
    *** inhibited by: CEP1347 [addition]
    *** source: 16230351-Fig-4b
  *** xSiah1[tAb]IP phos[32Pi] is increased itpo xMlk1
    *** cells: HEK293 in BMS
    *** source: 16230351-Fig-6a
  *** xSiah1[tAb]IP Yphos[pYAb] is increased itpo xMlk1
    *** cells: HEK293 in BMS
    *** partially inhibited by: xSiah1(Y100F) [substitution]
    *** partially inhibited by: xSiah1(Y126F) [substitution]
    *** inhibited by: xSiah1(Y100F/Y126F) [substitution]
    *** source: 16230351-Fig-6c
  *** Sin1[Ab] copptby[WB] Atf2[Ab] is detectable
    *** cells: HEK293T in BMS
    *** source: 17054722-Fig-4d
  *** Sin1[Ab] copptby[WB] Protor1[Ab] is detectable
    *** cells: HEK293 in BMS
    *** comment: coppt is unaffected by detergent used in lysis
    *** source: 17461779-Fig-3b
  *** Sin1[Ab] copptby[WB] Protor1[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 17461779-Fig-3a
  *** Sin1[Ab] copptby[WB] Raptor[Ab] is undetectable
    *** cells: HEK293T in BMS
    *** source: 16919458-Fig-1b
  *** Sin1[Ab] copptby[WB] Raptor[Ab] is undetectable
    *** cells: HEK293T in BMS
    *** source: 17277771-Fig-S1b
  *** Sin1[Ab] copptby[WB] Raptor[Ab] is undetectable
    *** cells: HELA in BMS
    *** source: 16919458-Fig-1b
  *** xSin1[Ab] copptby[WB] xProtor1[Ab] is detectable
    *** cells: HEK293<xMtor><xRictor><xSin1><xProtor1><xMlst8> in BMS
    *** does not req: xMtor [omission]
    *** does not req: xRictor [omission]
    *** source: 17461779-Fig-4a
  *** Sin1[Ab] copptby[WB] xProtor1[tAb] is detectable
    *** cells: HEK293<xProtor1> in BMS
    *** unaffected by: xProtor1b [substitution]
    *** inhibited by: xProtor1g [substitution]
    *** source: 17461779-Fig-2d
  *** Sin1[Ab] copptby[WB] xProtor2[tAb] is detectable
    *** cells: HEK293<xProtor1> in BMS
    *** source: 17461779-Fig-2d
  *** Sin1[Ab] prot-exp[WB] is detectable
    *** cells: mEFs in BMS
    *** partially reqs: Rictor [KO]
    *** source: 17461779-Fig-4b
  *** xSin1[tAb] colocwith[IHC] xAtf2[tAb] is detectable
    *** cells: HEK293T in BMS
    *** comment: colocalization takes place in the nucleus
    *** source: 17054722-Fig-4e
  *** xSin1[tAb] colocwith[IHC] xP38a[tAb] is detectable
    *** cells: HEK293T in BMS
    *** comment: colocalization takes place in the nucleus
    *** source: 17054722-Fig-4e
  *** xSin1[tAb] copptby[WB] xAtf2[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 17054722-Fig-4a
  *** xSin1[tAb] copptby[WB] xJnk1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 17054722-Fig-4c
  *** xSin1[tAb] copptby[WB] xP38a[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 17054722-Fig-4b
  *** xSin1[tAb]IP IVKA(Akt1)(S473)[phosAb] is detectable
    *** cells: HEK293<xMtor><xRictor> in BMS
    *** source: 17043309-Fig-4b
  *** xSin1[tAb]IP IVKA(Akt1)(S473)[phosAb] is undetectable
    *** cells: HEK293<xMtor><xRaptor> in BMS
    *** source: 17043309-Fig-4b
*** Sin3a--
  *** rSin3a[35S] boundby[WB] rElk1[His] is detectable
    *** cells: none
    *** enhanced by: rElk1{phos} [substitution]
    *** comment: rElk1 was phosed by rErk2{act}
    *** source: 11283259-Fig-4d
  *** rSin3a[35S] boundby[WB] rElk1[His] is detectable
    *** cells: none
    *** unaffected by: rElk1{phos} [substitution]
    *** comment: rElk1 was phosed by rErk2{act}
    *** source: 11283259-Fig-4d
  *** xSin3a[tAb] copptby[WB] xElk1(1-206)[Gal4-DBD] is detectable
    *** cells: HEK293<xSin3a><xElk1(1-206)> in BMS
    *** inhibited by: xElk1(205-428) [substitution]
    *** inhibited by: xElk1 [substitution]
    *** source: 11283259-Fig-4a
  *** xSin3a[tAb] copptby[WB] xElk1(1-208)[tAb] is detectable-but unchanged itpo xMek1(mnr)"CA"
    *** cells: HEK293<xSin3a><xElk1(1-208)> in BMS
    *** source: 11283259-Fig-5b
  *** xSin3a[tAb] copptby[WB] xElk1(S383A/S389A)[tAb] is detectable-but unchanged itpo xMek1(mnr)"CA"
    *** cells: HEK293<xSin3a><xElk1(S383A/S389A)> in BMS
    *** source: 11283259-Fig-5c
  *** xSin3a[tAb] copptby[WB] xElk1[Gal4-DBD] is increased itpo xMek1(mnr)"CA"
    *** cells: HEK293<xSin3a><xElk1> in BMS
    *** inhibited by: xSin3a(1-479) [substitution]
    *** source: 11283259-Fig-4b
  *** xSin3a[tAb] copptby[WB] xElk1[Gal4-DBD] is increased itpo xMek1(mnr)"CA"
    *** cells: HEK293<xSin3a><xElk1> in BMS
    *** source: 11283259-Fig-4a
  *** xSin3a[tAb] copptby[WB] xElk1[tAb] is increased itpo xMek1(mnr)"CA"
    *** cells: HEK293<xSin3a><xElk1> in BMS
    *** bkg inhibited by: U0126 [addition]
    *** source: 11283259-Fig-5a
  *** Sipa1[Ab] infraction(nuclear)[WB] is detectable
    *** cells: HL60 in BMS
    *** source: 9346962-Fig-4
  *** Sipa1[Ab] infraction(P100)[WB] is detectable
    *** cells: HL60 in BMS
    *** source: 9346962-Fig-4
  *** Sipa1[Ab] infraction(S100)[WB] is undetectable
    *** cells: HL60 in BMS
    *** source: 9346962-Fig-4
  *** rSirt1[32P] phos[32P-ATP] is unchanged by pAmpk
    *** cells: none
    *** source: 17711846-Fig-1b
*** Skil--
  *** xSkil[tAb] copptby[WB] xSmurf2(mnr)"CIA"[tAb] is detectable
    *** cells: HEK293T<xSmad2><xTgfbR1(mnr)"CA"> in BMS
    *** inhibited by: xSmad2(del(221-225))"del-PY" [substitution]
    *** source: 11389444-Fig-6b
  *** xSkil[tAb] copptby[WB] xSmurf2[tAb] is increased itpo xSmad2
    *** cells: HEK293T<xTgfbR1(mnr)"CA"> in BMS "treated with Lactacystin"
    *** source: 11389444-Fig-3b
  *** xSkil[tAb] prot-exp[WB] is decreased itpo xSmad2
    *** cells: HEK293T<xSmurf2> in BMS
    *** source: 11389444-Fig-4c
  *** xSkil[tAb] prot-exp[WB] is decreased itpo xSmad2
    *** cells: HEK293T<xTgfbR1(mnr)"CA"><xSmurf2> in BMS
    *** reversed by: xSmurf2(C716A)"CIA" [substitution]
    *** source: 11389444-Fig-3b
  *** xSkil[tAb]IP prot-exp[WB] is decreased itpo (xSmurf2 + xSmad2)
    *** cells: HEK293T in BMS
    *** reqs: xSmad2 [omission]
    *** reversed by: xSmurf2(C716A)"CIA" [substitution]
    *** source: 11389444-Fig-7a
  *** xSkil[tAb]IP prot-exp[WB] is decreased itpo (xSmurf2 + xSmad2)
    *** cells: HEK293T in BMS
    *** unaffected by: xTgfbR1(mnr)"CA" [addition]
    *** source: 11389444-Fig-7a
  *** xSkil[tAb]IP prot-stability[35S-pulse-chase] is decreased itpo (xSmad2 + xSmurf2)
    *** cells: HEK293T in BMS
    *** unaffected by: xTgfbR1(mnr)"CA" [addition]
    *** source: 11389444-Fig-5b
  *** xSkil[tAb]IP prot-stability[35S-pulse-chase] is increased itpo (xSmad2 + xSmurf2(mnr)"CIA")
    *** cells: HEK293T in BMS
    *** source: 11389444-Fig-6e
  *** xSkil[tAb]IP prot-stability[35S-pulse-chase] is increased itpo (xSmad2 + xTgfbR1(mnr)"CA" + xSmurf2(mnr)"CIA")
    *** cells: HEK293T in BMS
    *** source: 11389444-Fig-5b
  *** xSkil[tAb]IP prot-stability[35S-pulse-chase] is unchanged itpo (xSmad2 + xTgfbR1(mnr)"CA")
    *** cells: HEK293T in BMS
    *** source: 11389444-Fig-5b
  *** xSkil[tAb]IP prot-stability[35S-pulse-chase] is unchanged itpo (xSmad2(del(221-225))"del-PY" + xSmurf2(mnr)"CIA")
    *** cells: HEK293T in BMS
    *** source: 11389444-Fig-6e
  *** xSkil[tAb]IP prot-stability[35S-pulse-chase] is unchanged itpo (xSmad2(del(221-225))"del-PY" + xSmurf2)
    *** cells: HEK293T in BMS
    *** source: 11389444-Fig-6e
  *** xSkil[tAb]IP prot-stability[35S-pulse-chase] is unchanged itpo (xSmurf2 + xTgfbR1(mnr)"CA")
    *** cells: HEK293T in BMS
    *** source: 11389444-Fig-5b
  *** xSkil[tAb]IP ubiq[tUbAb] is detectable
    *** cells: HEK293T<xUbiq> in BMS
    *** comment: IPs were boiled in 1% SDS and reIPed
    *** unaffected by: xSmad2 [addition]
    *** unaffected by: xSmad2 + xTgfbR1(mnr)"CA" [addition]
    *** unaffected by: xSmurf2 [addition]
    *** unaffected by: xSmurf2 + xTgfbR1(mnr)"CA" [addition]
    *** enhanced by: xSmad2 + xSmurf2 [addition]
    *** enhanced by: xSmad2 + xSmurf2 + xTgfbR1(mnr)"CA" [addition]
    *** source: 11389444-Fig-5a
*** Skp1--
  *** Skp1[Ab] copptby[WB] xBtrc[tAb] is detectable
    *** cells: HEK293 in BMS "pretreated with MG132"
    *** unaffected by: CalyculinA [addition]
    *** inhibited by: xBtrc(mnr)"F-box-deletion-mutant" [substitution]
    *** source: 9990853-Fig-1b
  *** Skp1[Ab] copptby[WB] xFbxo11[tAb] is detectable
    *** cells: HEK293<xFbxo11> in BMS "nuclear extracts"
    *** inhibited by: xFbxo11(del(152-197)) [substitution]
    *** source: 17098746-Fig-2b
*** Slc12a1--
*** Slc12a1--
*** Slc12a1--
  *** rSlc12a1(Nterm)[32P] phos[32P-ATP] is increased by rOxsr1
    *** cells: none
    *** source: 16263722(D)
  *** rSlc12a1(Nterm)[32P] phos[32P-ATP] is increased by rStk39
    *** cells: none
    *** source: 16263722(D)
  *** rSlc12a2(Nterm)[32P] phos[32P-ATP] is increased by rOxsr1
    *** cells: none
    *** source: 16263722(D)
  *** rSlc12a2(Nterm)[32P] phos[32P-ATP] is increased by rStk39
    *** cells: none
    *** source: 16263722(D)
  *** rSlc12a3(Nterm)[32P] phos[32P-ATP] is increased by rOxsr1
    *** cells: none
    *** source: 16263722(D)
  *** rSlc12a3(Nterm)[32P] phos[32P-ATP] is increased by rStk39
    *** cells: none
    *** source: 16263722(D)
  *** rSmad1 oligo-binding[EMSA] is undetectable
    *** cells: none
    *** oligo: AP1 5-CGCTTGATGAGTCAGCCGGAA-3
    *** unaffected by: rSmad1(mnr)"LN-term" [substitution]
    *** source: 9732876-Fig-3a
*** Smad1--
  *** rSmad1(mnr)"MH1-domain" oligo-binding[EMSA] is detectable
    *** cells: none
    *** oligo: SBE 5-AGTATGTCTAGAC TGA-3
    *** source: 14993291-Fig-4a
  *** rSmad1(mnr)"MH1-domain" oligo-binding[EMSA] is undetectable
    *** cells: none
    *** oligo: "Myc-TIE" 5-TTCTCAGAGGCTTGGCGG GAAAAAGAACGG-3
    *** source: 14993291-Fig-4a
  *** Smad1[Ab] copptby[WB] Sptbn1[Ab] is undetectable
    *** cells: HEPG2 in BMS
    *** unaffected by: TgfbR1 (1 hr) [stim]
    *** source: 12543979-Fig-S2e
  *** xSmad1[phosAb] phos(S206)[phosAb] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: Bmp? (1 hr) [stim]
    *** source: 17085434-Fig-2a
  *** xSmad1[tAb] copptby[WB] xPias4[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 12904571-Fig-1b
  *** xSmad1[tAb] copptby[WB] xSara[tAb] is undetectable
    *** cells: COS in BMS
    *** source: 9865696-Fig-2c
  *** xSmad1[tAb] copptby[WB] xSmurf1(C710A)"CIA"[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 11278251-Fig-1b
  *** xSmad1[tAb] copptby[WB] xSmurf2[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 11163210-Fig-1a
  *** xSmad1[tAb] copptby[WB] xStrap[tAb] is undetectable
    *** cells: COS1 in BMS
    *** source: 10757800(D)
  *** xSmad1[tAb] copptby[WB] xUbiq[tAb] is increased itpo xSmurf2
    *** cells: COS1 in BMS
    *** inhibited by: xSmurf2(C716G)"CIA" [substitution]
    *** source: 11158580-Fig-3d
  *** xSmad1[tAb] copptby[WB] xZfyve16[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 17272273-Fig-4a
  *** xSmad1[tAb] prot-exp[WB] is decreased itpo xSmurf2
    *** cells: COS1 in BMS
    *** inhibited by: Lactacystin [addition]
    *** source: 11158580-Fig-3b
  *** xSmad1[tAb] prot-exp[WB] is decreased itpo xSmurf2
    *** cells: COS1 in BMS
    *** inhibited by: xSmurf2(C716G)"CIA" [substitution]
    *** source: 11158580-Fig-3a
  *** xSmad1[tAb] prot-exp[WB] is unchanged itpo xSmurf2
    *** cells: HEK293 in BMS
    *** source: 11016919-Fig-2
  *** xSmad1[tAb] prot-exp[WB] is unchanged itpo xSmurf2
    *** cells: HEK293T in BMS
    *** source: 11163210-Fig-1a
  *** xSmad1[tAb] prot-stability[35S-pulse-chase] is decreased itpo xSmurf2
    *** cells: HEK293T in BMS
    *** inhibited by: Lactacystin [addition]
    *** source: 11158580-Fig-3c
  *** xSmad1[tAb] upshift[WBMS] is increased itpo xSmurf1
    *** cells: HEK293 in BMS
    *** source: 11359933-Fig-4a
  *** xSmad1[tAb]IP acetyl[KAcAb] is unchanged itpo xEp300
    *** cells: HEK293T in BMS
    *** source: 17478422-Fig-1a
  *** xSmad1[tAb]IP phos(S463/S465)[phosAb] is unchanged itpo xPpm1g
    *** cells: HEK293T<xTgfbR1(T202D)> in BMS
    *** source: 16751101-Fig-S14
  *** xSmad1[tAb]IP phos(S463/S465)[phosAb] is unchanged itpo xPpp1ca
    *** cells: HEK293T<xTgfbR1(T202D)> in BMS
    *** source: 16751101-Fig-S14
  *** xSmad1[tAb]IP phos[32Pi] is unchanged itpo xTgfbR1
    *** cells: COS1 in BMS
    *** source: 9748228(D)
  *** xSmad1[tAb]IP phos[32Pi] is unchanged itpo xTgfbR1(mnr)"CA"
    *** cells: COS1 in BMS
    *** source: 9748228(D)
  *** xSmad1[tAb]IP sumo[tSuAb] is increased itpo xUbe2i
    *** cells: HELA<xSumo1> in BMS
    *** source: 12740389-Fig-3b
  *** xSmad1[tAb]IP sumo[tSuAb] is unchanged itpo xSumo1
    *** cells: HELA in BMS
    *** source: 12740389-Fig-1b
  *** xSmad1[tAb]IP ubiq[tUbAb] is increased itpo xSmurf1
    *** cells: COS7<xUbiq> in BMS
    *** source: 11278251-Fig-3a
*** Smad2--
  *** xSmad2(1-463)[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMekk1(380-672)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-4a
  *** xSmad2(1-463)[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xMek1(del(32-51)/S218E/S222E)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-4a
  *** rSmad2(2-21)[32P] phos[32P-ATP] is increased by (rMek1(S218E/S222D)"CA" + rErk1)
    *** cells: none
    *** partially inhibited by: rSmad2(4-23) [substitution]
    *** inhibited by: rSmad2(78-88) [substitution]
    *** comment: phos was mostly on Threonine by phosphoamino acid analysis
    *** source: 12193595-Fig-2b
  *** xSmad2(mnr)"Cterm"[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMekk1(380-672)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-2a
  *** xSmad2(mnr)"Cterm"[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xMek1(del(32-51)/S218E/S222E)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-2a
  *** xSmad2(mnr)"del-MH2"[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xMek1(del(32-51)/S218E/S222E)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-4a
  *** xSmad2(mnr)"del-MH2"[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xMekk1(380-672)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-4a
  *** xSmad2(S464A/S465A/S467A)[tAb]IP phos[32Pi] is unchanged itpo xHras(G12V)"CA"
    *** cells: R1BL17<TgfbR1~null> in BMS
    *** source: 10197981-Fig-5e
  *** rSmad2[32P] phos[32P-ATP] is increased by (rCdk2{act} + rCyclinA2)
    *** cells: none
    *** comment: recombinant proteins were incubated with HELA extract to activate the Cdk4
    *** source: 15241418-Fig-1d
  *** rSmad2[32P] phos[32P-ATP] is increased by (rCdk2{act} + rCyclinE?)
    *** cells: none
    *** comment: recombinant proteins were incubated with HELA extract to activate the Cdk4
    *** source: 15241418-Fig-1d
  *** rSmad2[32P] phos[32P-ATP] is increased by (rCdk4{act} + rCyclinD?)
    *** cells: none
    *** comment: recombinant proteins were incubated with HELA extract to activate the Cdk4
    *** source: 15241418-Fig-1b
  *** rSmad2[32P] phos[32P-ATP] is increased by (rMek1(S218E/S222D)"CA" + rErk1)
    *** cells: none
    *** source: 12193595-Fig-1b
  *** Smad2[Ab] locatedin(nucleus)[IHC] is increased itpo xFoxh1
    *** cells: HELA in BMS
    *** source: 12191473-Fig-5b
  *** xSmad2[Gal4-DBD] boundby[MamTwoHybrid] xCbp(1891-2441)[VP16] is increased itpo xMekk1(380-672)"CA"
    *** cells: bAECs in BMS
    *** inhibited by: xCbp(1459-1891)[VP16] [substitution]
    *** inhibited by: xCbp(1069-1459)[VP16] [substitution]
    *** inhibited by: xCbp(706-1069)[VP16] [substitution]
    *** inhibited by: xCbp(1-771)[VP16] [substitution]
    *** source: 10085121-Fig-7a
  *** xSmad2[Gal4-DBD] boundby[MamTwoHybrid] xSmad2[VP16] is increased itpo xMekk1(380-672)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-5a
  *** xSmad2[Gal4-DBD] boundby[MamTwoHybrid] xSmad2[VP16] is unchanged itpo xMek1(del(32-51)/S218E/S222E)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-5a
  *** xSmad2[Gal4-DBD] boundby[MamTwoHybrid] xSmad4[VP16] is increased itpo xMekk1(380-672)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-5a
  *** xSmad2[Gal4-DBD] boundby[MamTwoHybrid] xSmad4[VP16] is unchanged itpo xMek1(del(32-51)/S218E/S222E)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-5a
  *** xSmad2[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMekk1(380-672)"CA"
    *** cells: bAECs in BMS
    *** inhibited by: xMekk1(mnr)"DN" [addition]
    *** inhibited by: xSmad7 [addition]
    *** source: 10085121-Fig-2b
  *** xSmad2[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMekk1(380-672)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-2a
  *** xSmad2[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xMek1(del(32-51)/S218E/S222E)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-2a
  *** xSmad2[MS2] nuc-export[NEreporter] is decreased itpo xFoxh1
    *** cells: HACAT in BMS
    *** source: 16751101-Fig-4g
  *** xSmad2[MS2] nuc-export[NEreporter] is increased itpo xPpm1a
    *** cells: HACAT in BMS
    *** inhibited by: xPpm1a(D239M) [substitution]
    *** source: 16751101-Fig-4g
  *** xSmad2[phosAb] phos(S465/S467)[phosAb] is increased itpo xRac1(Q61L)"CA"
    *** cells: PANC1<xSmad2> in BMS
    *** source: 21624123-Fig-7b
  *** Smad2[phosAb] phos(sitenr)[phosAb] is detectable
    *** cells: HEK293<xIL1R1><xIL1Rap> in BMS "pretreated with CHX"
    *** does not req: Irak1 [RNAi]
    *** does not req: Myd88 [RNAi]
    *** source: 17360530-Fig-2b
  *** Smad2[phosAb] phos(sitenr)[phosAb] is detectable
    *** cells: HEK293<xIL1R1><xIL1Rap> in BMS "pretreated with CHX"
    *** partially reqs: Irak1 [RNAi]
    *** partially reqs: Myd88 [RNAi]
    *** source: 17360530-Fig-2a
  *** Smad2[phosAb] phos(sitenr)[phosAb] is increased itpo xDnm1
    *** cells: HELA in BMS
    *** source: 12034739(D)
  *** xSmad2[tAb] copptby[WB] CbpP300[Ab] is increased itpo xMekk1(380-672)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-7b
  *** xSmad2[tAb] copptby[WB] CbpP300[Ab] is unchanged itpo xMek1(del(32-51)/S218E/S222E)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-7b
  *** xSmad2[tAb] copptby[WB] CbpP300[Ab] is unchanged itpo xTak1(mnr)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-7b
  *** xSmad2[tAb] copptby[WB] xPias4[tAb] is increased itpo xTgfbR1(T204D)"CA"
    *** cells: HEK293T in BMS
    *** source: 12904571-Fig-1c
  *** xSmad2[tAb] locatedin(nucleus)[IHC] is increased itpo xMekk1(380-672)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-6a
  *** xSmad2[tAb] locatedin(nucleus)[IHC] is unchanged itpo xMek1(del(32-51)/S218E/S222E)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-6a
  *** xSmad2[tAb] prot-stability[35S-pulse-chase] is unchanged itpo xEp300
    *** cells: HEK293T in BMS
    *** unaffected by: xSmad2(K19R/K20R/K39R) [substitution]
    *** source: 17478422-Fig-6a
  *** xSmad2[tAb]IP phos(S465/S467)[phosAb] is increased itpo xCdc34(mnr)"DN"
    *** cells: COS1 in BMS "treated with Tgfb1 (tnr)"
    *** source: 10587642-Fig-4d
  *** xSmad2[tAb]IP phos(S465/S467)[phosAb] is increased itpo xUbe2d2(mnr)"DN"
    *** cells: COS1 in BMS "treated with Tgfb1 (tnr)"
    *** source: 10587642-Fig-4d
  *** xSmad2[tAb]IP phos(S465/S467)[phosAb] is increased itpo xUbe2d3(mnr)"DN"
    *** cells: COS1 in BMS "treated with Tgfb1 (tnr)"
    *** source: 10587642-Fig-4d
  *** xSmad2[tAb]IP phos(S465/S467)[phosAb] is increased itpo xUbe2h(mnr)"DN"
    *** cells: COS1 in BMS "treated with Tgfb1 (tnr)"
    *** source: 10587642-Fig-4d
  *** xSmad2[tAb]IP phos[32Pi] is increased itpo xHras(G12V)"CA"
    *** cells: R1BL17<TgfbR1~null> in BMS
    *** inhibited by: PD98059 [addition] no-bkg-control
    *** unaffected by: Wortmannin [addition] no-bkg-control
    *** source: 10197981-Fig-5b
  *** xSmad2[tAb]IP phos[32Pi] is increased itpo xMek1(mnr)"CA"
    *** cells: R1BL17<TgfbR1~null> in BMS
    *** source: 10197981-Fig-5b
  *** xSmad2[tAb]IP phos[32Pi] is increased itpo xMekk1(380-672)"CA"
    *** cells: bAECs in BMS
    *** unaffected by: xSmad2(1-463) [substitution]
    *** source: 10085121-Fig-4b
  *** xSmad2[tAb]IP prot-stability[35S-pulse-chase] is increased itpo xMek1(S218E/S222D)"CA"
    *** cells: COS7 in BMS
    *** source: 12193595-Fig-5b
*** Smad3--
  *** rSmad3(1-145)"MH1"[tAb] nuc-import[IVnucImport] is increased by rKpnb1
    *** cells: none
    *** comment: rKpnb1 cannot be replaced by cytosol
    *** source: 12917407-Fig-5a
  *** rSmad3(146-425)"LMH2"[Ab] nuc-import[IVnucImport] is detectable
    *** cells: none
    *** inhibited by: rSmad3(1-145)"MH1" [substitution]
    *** comment: does not require cytosol
    *** source: 12917407-Fig-2a
  *** rSmad3(146-425)"LMH2"[Ab] nuc-import[IVnucImport] is detectable
    *** cells: none
    *** inhibited by: rSmad3(1-145)"MH1" [substitution]
    *** source: 12917407-Fig-3c
  *** rSmad3(146-425)"LMH2"[Ab] nuc-import[IVnucImport] is detectable
    *** cells: none
    *** inhibited by: rSmad3(1-185)"MH1" [substitution]
    *** inhibited by: rSmad3(231-425)"MH2" [substitution]
    *** comment: does not require cytosol
    *** source: 12917407-Fig-3a
  *** rSmad3(146-425)"LMH2"[tAb] nuc-import[IVnucImport] is detectable
    *** cells: none
    *** inhibited by: rSmad3((146-425)/V356R) [substitution]
    *** unaffected by: rSmad3((146-425)/P403H) [substitution]
    *** inhibited by: rSmad3((146-425)/W406A) [substitution]
    *** source: 12917407-Fig-7b
  *** rSmad3(146-425)"LMH2"[tAb] nuc-import[IVnucImport] is detectable
    *** cells: none
    *** unaffected by: rRan(Q69L){GTP} [addition]
    *** comment: does not require cytosol
    *** source: 12917407-Fig-4
  *** xSmad3(146-425)"LMH2"[XFP] locatedin(nucleus)[IHC] is detectable
    *** cells: HACAT in BMS
    *** source: 12917407-Fig-3b
  *** xSmad3(146-425)"LMH2"[XFP] locatedin(nucleus)[IHC] is detectable
    *** cells: HELA in BMS
    *** source: 12917407-Fig-3b
  *** xSmad3(mnr)"GAG-domain"[tAb]IP acetyl[KAcAb] is increased itpo xEp300
    *** cells: HEK293T in BMS
    *** source: 17478422-Fig-2d
  *** rSmad3(mnr)"MH1-domain" oligo-binding[EMSA] is detectable
    *** cells: none
    *** oligo: "Myc-TIE" 5-TTCTCAGAGGCTTGGCGGGAAAAAGAACGG-3
    *** source: 14993291-Fig-4a
  *** rSmad3(mnr)"MH1-domain" oligo-binding[EMSA] is detectable
    *** cells: none
    *** oligo: SBE 5-AGTATGTCTAGACTGA-3
    *** source: 14993291-Fig-4a
  *** xSmad3(S422A/S423A/S425A)[tAb]IP phos[32Pi] is increased itpo xHras(G12V)"CA"
    *** cells: R1BL17<TgfbR1~null> in BMS
    *** source: 10197981-Fig-5e
  *** rSmad3[14C] acetyl[14C-acetyl-CoA] is increased by rEp300(mnr)"HAT-domain"
    *** cells: none
    *** source: 17478422-Fig-1b
  *** rSmad3[32P] phos[32P-ATP] is increased by xPdpk1[tAb]IP
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** enhanced by: xStrap[tAb]IP [addition]
    *** source: 17327236-Fig-1d
  *** Smad3[Ab] copptby[WB] Pdpk1[Ab] is detectable
    *** cells: HEK293T in BMS
    *** source: 17327236-Fig-1c
  *** Smad3[Ab] copptby[WB] Sptbn1[Ab] is detectable
    *** cells: HEPG2 in BMS
    *** source: 12543979-Fig-2
  *** Smad3[Ab] infraction(cytoplasmic)[WB] is detectable
    *** cells: HEP3B in BMS "containing Tgfb1"
    *** reqs: Pdpk1 [RNAi]
    *** source: 17327236-Fig-9b
  *** Smad3[Ab] infraction(cytoplasmic)[WB] is detectable
    *** cells: HEP3B<xPdpk1> in BMS "containing Tgfb1"
    *** partially inhibited by: xPdpk1(mnr)"KD" [substitution]
    *** source: 17327236-Fig-9b
  *** Smad3[Ab] infraction(nuclear)[WB] is detectable
    *** cells: HEP3B in BMS "containing Tgfb1"
    *** repressed by: Pdpk1 [RNAi]
    *** source: 17327236-Fig-9b
  *** Smad3[Ab] infraction(nuclear)[WB] is detectable
    *** cells: HEP3B<xPdpk1> in BMS "containing Tgfb1"
    *** enhanced by: xPdpk1(mnr)"KD" [substitution]
    *** source: 17327236-Fig-9b
  *** rSmad3[Ab] nuc-import[IVnucImport] is decreased by rSara(767-852)"SBD"
    *** cells: none
    *** comment: does not require cytosol
    *** source: 12917407-Fig-1a
  *** rSmad3[Ab] nuc-import[IVnucImport] is detectable
    *** cells: none
    *** unaffected by: rSmad3(1-145)"MH1" [addition]
    *** inhibited by: rSmad3(146-425)"LMH2" [addition]
    *** source: 12917407-Fig-3d
  *** Smad3[Ab] prot-exp[WB] is decreased itpo xHras(mnr)"vRas"
    *** cells: EPH4 in BMS
    *** source: 10197981-Fig-2b
  *** Smad3[Ab]IP phos[32Pi] is detectable
    *** cells: MV1LUL17 in BMS
    *** enhanced by: xCyclinD? [addition]
    *** enhanced by: xCyclinE? [addition]
    *** enhanced by: xCyclinA2 [addition]
    *** source: 15241418-Fig-2d
  *** Smad3[Ab]IP phos[32Pi] is detectable
    *** cells: MV1LUL17 in BMS
    *** partially inhibited by: xCdkn2a [addition]
    *** partially inhibited by: xCdkn1a [addition]
    *** source: 15241418-Fig-2d
  *** Smad3[Ab]IP phos[32Pi] is increased itpo xCyclinD?
    *** cells: MV1LUL17 in BMS
    *** partially inhibited by: xCdkn2a [addition]
    *** source: 15241418-Fig-2d
  *** Smad3[Ab]IP phos[32Pi] is increased itpo xCyclinE?
    *** cells: MV1LUL17 in BMS
    *** partially inhibited by: xCdkn1a [addition]
    *** source: 15241418-Fig-2d
  *** Smad3[Ab]IP prot-stability[35S-pulse-chase] is decreased itpo xTgfbR1
    *** cells: R1BL17<TgfbR1~null> in BMS "treated with Tgfb1 (tnr)"
    *** source: 10587642-Fig-4c
  *** Smad3[Ab]IP STphos[pSTAb] is detectable
    *** cells: HEK293T in BMS
    *** reqs: Pdpk1 [RNAi]
    *** enhanced by: xPdpk1 [addition]
    *** inhibited by: xPdpk1(mnr)"KD" [addition]
    *** source: 17327236-Fig-1e
  *** xSmad3[Gal4-DBD] boundby[MamTwoHybrid] xFos[VP16] is detectable
    *** cells: F9 in BMS
    *** source: 9732876-Fig-2b
  *** xSmad3[Gal4-DBD] boundby[MamTwoHybrid] xJun[VP16] is detectable
    *** cells: F9 in BMS
    *** source: 9732876-Fig-2b
  *** xSmad3[Gal4-DBD] Gal4-reporter[Luc] is decreased itpo xPias4
    *** cells: MV1LUL17 in BMS
    *** source: 12904571-Fig-5c
  *** xSmad3[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xJun
    *** cells: F9 in BMS
    *** source: 9732876-Fig-1e
  *** xSmad3[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xFos
    *** cells: F9 in BMS
    *** source: 9732876-Fig-1e
  *** Smad3[phosAb] phos(S204)[phosAb] is detectable
    *** cells: mEFs in BMS
    *** reqs: Smad3 [KO]
    *** source: 15241418-Fig-S4d
  *** xSmad3[phosAb] phos(S204)[phosAb] is detectable
    *** cells: MV1LUL17 in BMS
    *** inhibited by: xSmad3(S204A) [substitution]
    *** source: 15241418-Fig-S4a
  *** Smad3[phosAb] phos(S208)[phosAb] is detectable
    *** cells: mEFs in BMS
    *** reqs: Smad3 [KO]
    *** source: 15241418-Fig-S4d
  *** xSmad3[phosAb] phos(S208)[phosAb] is detectable
    *** cells: MV1LUL17 in BMS
    *** inhibited by: xSmad3(S208A) [substitution]
    *** source: 15241418-Fig-S4a
  *** Smad3[phosAb] phos(S208/S213)[phosAb] is increased itpo xMek1(mnr)"CA"
    *** cells: hTECs in BMLS "plated on gelatin for 4 hr"
    *** source: 18032789-Fig-5b
  *** Smad3[phosAb] phos(S208/S213)[phosAb] is increased itpo xMek1(mnr)"CA"
    *** cells: hTECs in BMLS "plated on PLL for 4 hr"
    *** source: 18032789-Fig-5b
  *** Smad3[phosAb] phos(S213)[phosAb] is detectable
    *** cells: mEFs in BMS
    *** reqs: Smad3 [KO]
    *** source: 15241418-Fig-S4d
  *** xSmad3[phosAb] phos(S213)[phosAb] is detectable
    *** cells: MV1LUL17 in BMS
    *** inhibited by: xSmad3(S21A) [substitution]
    *** source: 15241418-Fig-S4a
  *** Smad3[phosAb] phos(S423/S425)[phosAb] is unchanged itpo xMek1(mnr)"CA"
    *** cells: hTECs in BMLS "plated on gelatin for 4 hr"
    *** source: 18032789-Fig-5b
  *** Smad3[phosAb] phos(S423/S425)[phosAb] is unchanged itpo xMek1(mnr)"CA"
    *** cells: hTECs in BMLS "plated on PLL for 4 hr"
    *** source: 18032789-Fig-5b
  *** Smad3[phosAb] phos(S423/S425)[phosAb] is unchanged itpo xMek1(S218D/S222D)
    *** cells: AKR2B in BMLS
    *** source: 23913859-Fig-3d
  *** Smad3[phosAb] phos(sitenr)[phosAb] is increased itao Smad2 [KO]
    *** cells: mEFs in BMS
    *** source: 20595680-Fig-7d
  *** Smad3[phosAb] phos(sitenr)[phosAb] is unchanged itpo xSmad2
    *** cells: mTECs in BMS
    *** source: 20595680-Fig-10b
  *** Smad3[phosAb] phos(T8)[phosAb] is detectable
    *** cells: mEFs in BMS
    *** reqs: Smad3 [KO]
    *** source: 15241418-Fig-S4d
  *** xSmad3[phosAb] phos(T8)[phosAb] is detectable
    *** cells: MV1LUL17 in BMS
    *** inhibited by: xSmad3(T8V) [substitution]
    *** source: 15241418-Fig-S4a
  *** Smad3[phosAb] phos(T179)[phosAb] is detectable
    *** cells: mEFs in BMS
    *** reqs: Smad3 [KO]
    *** source: 15241418-Fig-S4d
  *** xSmad3[phosAb] phos(T179)[phosAb] is detectable
    *** cells: MV1LUL17 in BMS
    *** inhibited by: xSmad3(T179V) [substitution]
    *** source: 15241418-Fig-S4a
  *** xSmad3[tAb] copptby[WB] Pdpk1[Ab] is detectable
    *** cells: HEK293T in BMS
    *** source: 17327236-Fig-1b
  *** xSmad3[tAb] copptby[WB] xAcvR1b(mnr)"KD"[tAb] is increased itpo xHgs
    *** cells: COS7<xAcvR2> in BMS
    *** reqs: xAcvR1b(mnr)"KD" [omission]
    *** inhibited by: xAcvR1b [substitution]
    *** source: 11094085(D)
  *** xSmad3[tAb] copptby[WB] xAtf2[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 10085140-Fig-3
  *** xSmad3[tAb] copptby[WB] xPdpk1[GST] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xSmad3(1-136) [substitution]
    *** partially inhibited by: xSmad3(1-231) [substitution]
    *** unaffected by: xSmad3(231-425) [substitution]
    *** unaffected by: xSmad3(136-425) [substitution]
    *** source: 17327236-Fig-2b
  *** xSmad3[tAb] copptby[WB] xPdpk1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 17327236-Fig-1a
  *** xSmad3[tAb] copptby[WB] xPias4[tAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xSmad3(mnr)"N-term" [substitution]
    *** unaffected by: xSmad3(mnr)"C-term" [substitution]
    *** unaffected by: xSmad3(mnr)"LC-term" [substitution]
    *** source: 12904571-Fig-1d
  *** xSmad3[tAb] copptby[WB] xPias4[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 12904571-Fig-1b
  *** xSmad3[tAb] copptby[WB] xPias4[tAb] is increased itpo xSmad4
    *** cells: COS in BMS
    *** source: 12904571-Fig-2b
  *** xSmad3[tAb] copptby[WB] xPias4[tAb] is increased itpo xTgfbR1(T204D)"CA"
    *** cells: HEK293T in BMS
    *** source: 12904571-Fig-1c
  *** xSmad3[tAb] copptby[WB] xPias4[tAb] is increased itpo xTgfbR1(T204D)"CA"
    *** cells: HEK293T in BMS
    *** source: 12904571-Fig-1d
  *** xSmad3[tAb] copptby[WB] xRbx1[tAb] is increased itpo xEp300
    *** cells: COS7 in BMS
    *** source: 11359933-Fig-5b
  *** xSmad3[tAb] copptby[WB] xRbx1[tAb] is increased itpo xSmad4
    *** cells: COS7 in BMS
    *** source: 11359933-Fig-2e
  *** xSmad3[tAb] copptby[WB] xRbx1[tAb] is increased itpo xTgfbR1(T204D)"CA"
    *** cells: COS7 in BMS
    *** source: 11359933-Fig-2d,5b
  *** xSmad3[tAb] copptby[WB] xSara[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 9865696-Fig-2c
  *** xSmad3[tAb] copptby[WB] xSmad2[tAb] is unchanged itpo xCamk2a(del(1-290))"CA"
    *** cells: HEK293 in BMS
    *** source: 11027280(D)
  *** xSmad3[tAb] copptby[WB] xSmad4[tAb] is decreased itpo xVps39
    *** cells: COS1 in BMLS
    *** source: 12941698-Fig-8a
  *** xSmad3[tAb] copptby[WB] xSmad4[tAb] is increased itpo xTgfbR1(mnr)"CA"
    *** cells: COS1 in BMLS
    *** source: 12941698-Fig-8a
  *** xSmad3[tAb] copptby[WB] xSmurf1(C710A)"CIA"[tAb] is undetectable
    *** cells: COS7 in BMS
    *** source: 11278251-Fig-1b
  *** xSmad3[tAb] copptby[WB] xStrap[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 10757800(D)
  *** xSmad3[tAb] copptby[WB] xTgfbR1(mnr)"CA"[tAb] is decreased itpo xPdpk1
    *** cells: HEK293 in BMS
    *** reversed by: xPdpk1(mnr)"KD" [substitution]
    *** source: 17327236-Fig-8a
  *** xSmad3[tAb] copptby[WB] xTgfbR1(mnr)"CA"[tAb] is detectable
    *** cells: HEK293 in BMS
    *** repressed by: Pdpk1 [RNAi]
    *** source: 17327236-Fig-8a
  *** xSmad3[tAb] copptby[WB] xTgfbR1(mnr)"CA"[tAb] is detectable
    *** cells: HEK293 in BMS
    *** reqs: Pdpk1 [RNAi]
    *** source: 17327236-Fig-8b
  *** xSmad3[tAb] copptby[WB] xTgfbR1(mnr)"CA"[tAb] is increased itpo xPdpk1
    *** cells: HEK293 in BMS
    *** inhibited by: xPdpk1(mnr)"KD" [substitution]
    *** source: 17327236-Fig-8b
  *** xSmad3[tAb] copptby[WB] xUbiq[tAb] is unchanged itpo xSmurf2
    *** cells: COS1 in BMS
    *** source: 11158580-Fig-3d
  *** xSmad3[tAb] copptby[WB] xZfyve16[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 17272273-Fig-4a
  *** xSmad3[tAb] locatedin(nucleus)[IHC] is decreased itpo xMek1(mnr)"CA"
    *** cells: MV1LU in BMS "treated with Tgfb1 for 30 min"
    *** reversed by: xMek1(mnr)"CA" [addition]
    *** source: 10197981-Fig-7
  *** xSmad3[tAb] locatedin(nucleus)[IHC] is increased itpo xTgfbR1(T204D)"CA"
    *** cells: COS7 in BMS
    *** source: 11359933-Fig-6b
  *** xSmad3[tAb] oligo-binding[EMSA] is detectable
    *** cells: COS1<xTgfbR1(mnr)"CA"><xTgfbR2><xSmad4><xJun><xFos> in BMS
    *** oligo: AP1 5-CGCTTGATGAGTCAGCCGGAA-3
    *** source: 9732876-Fig-3f
  *** xSmad3[tAb] phos(S204)[phosAb-ppt] is detectable
    *** cells: MV1LUL17 in BMS
    *** inhibited by: xSmad3(S204A) [substitution]
    *** source: 15241418-Fig-S4b
  *** xSmad3[tAb] phos(S208)[phosAb-ppt] is detectable
    *** cells: MV1LUL17 in BMS
    *** inhibited by: xSmad3(S208A) [substitution]
    *** source: 15241418-Fig-S4b
  *** xSmad3[tAb] phos(S213)[phosAb-ppt] is detectable
    *** cells: MV1LUL17 in BMS
    *** inhibited by: xSmad3(S213A) [substitution]
    *** source: 15241418-Fig-S4b
  *** xSmad3[tAb] phos(T8)[phosAb-ppt] is detectable
    *** cells: MV1LUL17 in BMS
    *** inhibited by: xSmad3(T8V) [substitution]
    *** source: 15241418-Fig-S4b
  *** xSmad3[tAb] phos(T179)[phosAb-ppt] is detectable
    *** cells: MV1LUL17 in BMS
    *** inhibited by: xSmad3(T179V) [substitution]
    *** source: 15241418-Fig-S4b
  *** xSmad3[tAb] prot-exp[WB] is increased itpo xSmurf2
    *** cells: COS1 in BMS
    *** inhibited by: xSmurf2(C716G)"CIA" [substitution]
    *** source: 11158580-Fig-3a
  *** xSmad3[tAb] prot-exp[WB] is unchanged itpo xSmurf2
    *** cells: HEK293 in BMS
    *** source: 11016919-Fig-2
  *** xSmad3[tAb] snaggedby[WB] oligo[biotin] is detectable
    *** cells: COS1<xTgfbR1(mnr)"CA"><xTgfbR2> in BMS
    *** oligo: AP1 5-CGCTTGATGAGTCAGCCGGAA-3
    *** source: 9732876-Fig-3d
  *** xSmad3[tAb] snaggedby[WB] rNup214(1805-2091)[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 12917407-Fig-6b
  *** xSmad3[tAb] snaggedby[WB] xSara(665-750)"SBD"[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 9865696-Fig-6b
  *** xSmad3[tAb] upshift[WBMS] is increased itpo (xBtrc + xCul1 + xRbx1)
    *** cells: COS7<xUbiq> in BMS "treated with MG132"
    *** reqs: xBtrc [omission]
    *** reqs: xCul1 [omission]
    *** reqs: xRbx1 [omission]
    *** enhanced by: xTgfbR1(T204D)"CA" [addition]
    *** source: 11359933-Fig-3a
  *** xSmad3[tAb]IP acetyl[KAcAb] is unchanged itpo xEp300
    *** cells: HEK293T in BMS
    *** source: 17478422-Fig-1a
  *** xSmad3[tAb]IP acetyl[KAcAb] is unchanged itpo xEp300
    *** cells: HEK293T in BMS
    *** source: 17478422-Fig-2b
  *** xSmad3[tAb]IP acetyl[KAcAb] is unchanged itpo xEp300
    *** cells: HEK293T in BMS
    *** source: 17478422-Fig-2d
  *** xSmad3[tAb]IP acetyl[KAcAb] is unchanged itpo xPcaf
    *** cells: HEK293T in BMS
    *** source: 17074756-Fig-2d
  *** xSmad3[tAb]IP phos(S70)[2D-PPMap] is increased by pPkcs(CatDom)
    *** cells: none
    *** IPfrom: COS1 in BMS
    *** source: 11259364(D)
  *** xSmad3[tAb]IP phos(S204)[phosAb] is detectable
    *** cells: HEK293T<xSmad2> in BMS
    *** inhibited by: xCtdsp2 [addition]
    *** partially inhibited by: xCtdspL [addition]
    *** partially inhibited by: xCtdspL2 [addition]
    *** source: 17035229-Fig-5a
  *** xSmad3[tAb]IP phos(S204)[phosAb] is detectable
    *** cells: HEK293T<xSmad2> in BMS
    *** unaffected by: Tgfb1 (1 hr) [stim]
    *** unaffected by: xPpm1a [addition]
    *** source: 17035229-Fig-2a
  *** xSmad3[tAb]IP phos(S204)[phosAb] is detectable
    *** cells: HEK293T<xSmad2> in BMS
    *** unaffected by: xCtdp1a [addition]
    *** source: 17035229-Fig-5b
  *** xSmad3[tAb]IP phos(S204)[phosAb] is detectable
    *** cells: HEK293T<xSmad2> in BMS
    *** unaffected by: xPpp1ca [addition]
    *** unaffected by: xPpp1cc [addition]
    *** unaffected by: xPpp2ca [addition]
    *** unaffected by: xPpp2cb [addition]
    *** unaffected by: xPpp3ca [addition]
    *** source: 17035229-Fig-1c
  *** xSmad3[tAb]IP phos(S208)[phosAb] is detectable
    *** cells: HEK293T<xSmad2> in BMS
    *** inhibited by: xCtdsp2 [addition]
    *** partially inhibited by: xCtdspL [addition]
    *** partially inhibited by: xCtdspL2 [addition]
    *** source: 17035229-Fig-5a
  *** xSmad3[tAb]IP phos(S208)[phosAb] is detectable
    *** cells: HEK293T<xSmad2> in BMS
    *** unaffected by: Tgfb1 (1 hr) [stim]
    *** unaffected by: xPpm1a [addition]
    *** source: 17035229-Fig-2a
  *** xSmad3[tAb]IP phos(S208)[phosAb] is detectable
    *** cells: HEK293T<xSmad2> in BMS
    *** unaffected by: xCtdp1a [addition]
    *** source: 17035229-Fig-5b
  *** xSmad3[tAb]IP phos(S208)[phosAb] is detectable
    *** cells: HEK293T<xSmad2> in BMS
    *** unaffected by: xPpp1ca [addition]
    *** unaffected by: xPpp1cc [addition]
    *** unaffected by: xPpp2ca [addition]
    *** unaffected by: xPpp2cb [addition]
    *** unaffected by: xPpp3ca [addition]
    *** source: 17035229-Fig-1c
  *** xSmad3[tAb]IP phos(S212)[phosAb] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xPpm1a [addition]
    *** unaffected by: Tgfb1 (tnr) [stim]
    *** source: 16751101-Fig-2i
  *** xSmad3[tAb]IP phos(S213)[phosAb] is detectable
    *** cells: HEK293T<xSmad2> in BMS
    *** unaffected by: Tgfb1 (1 hr) [stim]
    *** unaffected by: xPpm1a [addition]
    *** source: 17035229-Fig-2a
  *** xSmad3[tAb]IP phos(S213)[phosAb] is detectable
    *** cells: HEK293T<xSmad2> in BMS
    *** unaffected by: xCtdsp1(D96E/D98N)"CIA" [addition]
    *** inhibited by: xCtdsp2 [addition]
    *** partially inhibited by: xCtdspL [addition]
    *** partially inhibited by: xCtdspL2 [addition]
    *** source: 17035229-Fig-5a
  *** xSmad3[tAb]IP phos(S213)[phosAb] is detectable
    *** cells: HEK293T<xSmad2> in BMS
    *** unaffected by: xPpp1ca [addition]
    *** unaffected by: xPpp1cc [addition]
    *** unaffected by: xPpp2ca [addition]
    *** unaffected by: xPpp2cb [addition]
    *** unaffected by: xPpp3ca [addition]
    *** source: 17035229-Fig-1c
  *** xSmad3[tAb]IP phos(S423/S425)[phosAb] is detectable
    *** cells: HEK293T<xSmad2> in BMS
    *** enhanced by: Tgfb1 (1 hr) [stim]
    *** inhibited by: xPpm1a [addition]
    *** source: 17035229-Fig-2a
  *** xSmad3[tAb]IP phos(T8)[phosAb] is detectable
    *** cells: HEK293T<xSmad2> in BMS
    *** inhibited by: xCtdsp2 [addition]
    *** unaffected by: xCtdspL [addition]
    *** unaffected by: xCtdspL2 [addition]
    *** source: 17035229-Fig-5a
  *** xSmad3[tAb]IP phos(T8)[phosAb] is detectable
    *** cells: HEK293T<xSmad2> in BMS
    *** unaffected by: Tgfb1 (1 hr) [stim]
    *** unaffected by: xPpm1a [addition]
    *** source: 17035229-Fig-2a
  *** xSmad3[tAb]IP phos(T8)[phosAb] is detectable
    *** cells: HEK293T<xSmad2> in BMS
    *** unaffected by: xCtdp1a [addition]
    *** source: 17035229-Fig-5b
  *** xSmad3[tAb]IP phos(T8)[phosAb] is detectable
    *** cells: HEK293T<xSmad2> in BMS
    *** unaffected by: xPpp1ca [addition]
    *** unaffected by: xPpp1cc [addition]
    *** unaffected by: xPpp2ca [addition]
    *** unaffected by: xPpp2cb [addition]
    *** unaffected by: xPpp3ca [addition]
    *** source: 17035229-Fig-1c
  *** xSmad3[tAb]IP phos(T179)[phosAb] is detectable
    *** cells: HEK293T<xSmad2> in BMS
    *** partially inhibited by: xCtdsp2 [addition]
    *** unaffected by: xCtdspL [addition]
    *** unaffected by: xCtdspL2 [addition]
    *** source: 17035229-Fig-5a
  *** xSmad3[tAb]IP phos(T179)[phosAb] is detectable
    *** cells: HEK293T<xSmad2> in BMS
    *** unaffected by: Tgfb1 (1 hr) [stim]
    *** unaffected by: xPpm1a [addition]
    *** source: 17035229-Fig-2a
  *** xSmad3[tAb]IP phos(T179)[phosAb] is detectable
    *** cells: HEK293T<xSmad2> in BMS
    *** unaffected by: xCtdp1a [addition]
    *** source: 17035229-Fig-5b
  *** xSmad3[tAb]IP phos(T179)[phosAb] is detectable
    *** cells: HEK293T<xSmad2> in BMS
    *** unaffected by: xPpp1ca [addition]
    *** unaffected by: xPpp1cc [addition]
    *** unaffected by: xPpp2ca [addition]
    *** unaffected by: xPpp2cb [addition]
    *** unaffected by: xPpp3ca [addition]
    *** source: 17035229-Fig-1c
  *** xSmad3[tAb]IP phos[32Pi] is detectable
    *** cells: R1BL17<TgfbR1~null> in BMS
    *** inhibited by: xSmad2(S422A/S423A/S425A) [substitution]
    *** source: 10197981-Fig-6a
  *** xSmad3[tAb]IP phos[32Pi] is detectable
    *** cells: R1BL17<TgfbR1~null> in BMS
    *** inhibited by: xSmad3(T179V/S204A/S208A/S213A) [substitution]
    *** source: 10197981-Fig-5c
  *** xSmad3[tAb]IP phos[32Pi] is unchanged itpo xCamk2a(del(1-290))"CA"
    *** cells: HEK293 in BMS
    *** source: 11027280(D)
  *** xSmad3[tAb]IP Sphos[pSAb] is increased itpo xAcvR1b
    *** cells: COS7<xAcvR2><xHgs> in BMS "treated with Inha (10 min)"
    *** inhibited by: xAcvR1b(mnr)"KD" [substitution]
    *** source: 11094085(D)
  *** xSmad3[tAb]IP Sphos[pSAb] is increased itpo xHgs
    *** cells: COS7<xAcvR2><xAcvR1b> in BMS
    *** source: 11094085(D)
  *** xSmad3[tAb]IP ubiq[tUbAb] is increased itpo (xBtrc + xCul1 + xRbx1)
    *** cells: COS7<xUbiq> in BMS "treated with MG132"
    *** reqs: xBtrc [omission]
    *** reqs: xCul1 [omission]
    *** reqs: xRbx1 [omission]
    *** enhanced by: xTgfbR1(T204D)"CA" [addition]
    *** source: 11359933-Fig-3b
  *** xSmad3[XFP] locatedin(perinuclear-region)[IHC] is detectable
    *** cells: mEFs<xSara> in BMS
    *** reqs: Pml [KO]
    *** source: 15356634-Fig-S5
  *** xSmad3[XFP] locatedin(perinuclear-region)[IHC] is increased itpo xPmlc
    *** cells: COS1 in BMS
    *** unaffected by: xSara [addition]
    *** source: 15356634-Fig-S4
  *** xSmad3[XFP] locatedin(perinuclear-region)[IHC] is increased itpo xSara
    *** cells: COS1 in BMS
    *** enhanced by: xPmlc [addition]
    *** source: 15356634-Fig-S4
  *** Smad3{phos(S208/S213)}[phosAb] locatedin(cytoplasm)[IHC] is detectable
    *** cells: RGM1 in BMLS "treated with Hgf for 60 min"
    *** comment: phos signal is inhibited by SP600125"
    *** source: 15326485-Fig-6a,6b
  *** Smad3{phos(S208/S213)}[phosAb] locatedin(cytoplasm)[IHC] is detectable
    *** cells: RGM1 in BMLS "treated with Tgfb1 for 60 min"
    *** comment: phos signal is inhibited by SP600125"
    *** source: 15326485-Fig-6a,6b
  *** Smad3{phos(S423/S425)}[phosAb] locatedin(nucleus)[IHC] is detectable
    *** cells: RGM1 in BMLS "treated with Hgf for 60 min"
    *** comment: phos signal is inhibited by SP600125"
    *** source: 15326485-Fig-6a,6b
  *** Smad3{phos(S423/S425)}[phosAb] locatedin(nucleus)[IHC] is detectable
    *** cells: RGM1 in BMLS "treated with Tgfb1 for 60 min"
    *** comment: phos signal is unaffected by SP600125"
    *** source: 15326485-Fig-6a,6b
  *** rSmad4 oligo-binding[EMSA] is detectable
    *** cells: none
    *** oligo: PAI1-PE21 5-CCTAGACAGACAAAACCTAGACAATCACGTG-3
    *** comment: details of oligo sequence requirements not curated
    *** comment: rSmad4 can form a complex with rSmad3 and rTfe3 at this site
    *** source: 12551947-Fig-1a,1b,1c
  *** rSmad4 oligo-binding[EMSA] is undetectable
    *** cells: none
    *** oligo: AP1 5-CGCTTGATGAGTCAGCCGGAA-3
    *** unaffected by: rSmad4(mnr)"LN-term" [substitution]
    *** source: 9732876-Fig-3a
*** Smad4--
  *** rSmad4(146-552)"LMH2"[Ab] nuc-import[IVnucImport] is detectable
    *** cells: none
    *** inhibited by: rSmad4(1-145)"MH1" [substitution]
    *** source: 12917407-Fig-2b
  *** rSmad4(146-552)"LMH2"[Fluor] nuc-import[IVnucImport] is detectable
    *** cells: none
    *** unaffected by: rRan(Q69L){GTP} [addition]
    *** comment: does not require cytosol
    *** source: 12917407-Fig-4
  *** xSmad4(mnr)"Cterm"[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xMekk1(380-672)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-2a
  *** xSmad4(mnr)"Cterm"[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xMek1(del(32-51)/S218E/S222E)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-2a
  *** xSmad4(R100T)[tAb]IP prot-stability[35S-pulse-chase] is detectable
    *** cells: HELA in BMS
    *** enhanced by: xSmad4(R100T/K159R) [substitution]
    *** source: 12740389-Fig-5b
  *** xSmad4(R100T)[tAb]IP prot-stability[35S-pulse-chase] is detectable
    *** cells: HELA in BMS
    *** enhanced by: xSumo1 + Ube2i + Pias4 [addition]
    *** source: 12740389-Fig-5c
  *** rSmad4[14C] acetyl[14C-acetyl-CoA] is increased by rEp300(mnr)"HAT-domain"
    *** cells: none
    *** source: 17478422-Fig-1b
  *** rSmad4[32P] phos[32P-ATP] is increased by xPdpk1[tAb]IP
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** enhanced by: xStrap[tAb]IP [addition]
    *** source: 17327236-Fig-1d
  *** rSmad4[32P] phos[32P-ATP] is unchanged by (rCdk2{act} + rCyclinA2)
    *** cells: none
    *** comment: recombinant proteins were incubated with HELA extract to activate the Cdk4
    *** source: 15241418-Fig-1d
  *** rSmad4[32P] phos[32P-ATP] is unchanged by (rCdk2{act} + rCyclinE?)
    *** cells: none
    *** comment: recombinant proteins were incubated with HELA extract to activate the Cdk4
    *** source: 15241418-Fig-1d
  *** rSmad4[32P] phos[32P-ATP] is unchanged by (rCdk4{act} + rCyclinD?)
    *** cells: none
    *** comment: recombinant proteins were incubated with HELA extract to activate the Cdk4
    *** source: 15241418-Fig-1b
  *** rSmad4[32P] phos[32P-ATP] is unchanged by (rMek1(S218E/S222D)"CA" + rErk1)
    *** cells: none
    *** source: 12193595-Fig-1b
  *** Smad4[Ab] copptby[WB] Sptbn1[Ab] is undetectable
    *** cells: HEPG2 in BMS
    *** source: 12543979-Fig-2
  *** xSmad4[Ab] copptby[WB] xPias4[Ab] is detectable
    *** cells: HELA in BMS
    *** unaffected by: xSmad4(K122R/K159R) [substitution]
    *** source: 12740389-Fig-4d
  *** Smad4[Ab] copptby[WB] xZfyve16[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 17272273-Fig-4b
  *** xSmad4[Ab] copptby[WB] xZfyve16[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 17272273-Fig-4b
  *** Smad4[Ab] infraction(cytoplasmic)[WB] is detectable
    *** cells: HEP3B in BMS "containing Tgfb1"
    *** reqs: Pdpk1 [RNAi]
    *** source: 17327236-Fig-9d
  *** Smad4[Ab] infraction(cytoplasmic)[WB] is detectable
    *** cells: HEP3B<xPdpk1> in BMS "containing Tgfb1"
    *** partially inhibited by: xPdpk1(mnr)"KD" [substitution]
    *** source: 17327236-Fig-9d
  *** Smad4[Ab] infraction(nuclear)[WB] is detectable
    *** cells: HEP3B in BMS "containing Tgfb1"
    *** repressed by: Pdpk1 [RNAi]
    *** source: 17327236-Fig-9d
  *** Smad4[Ab] infraction(nuclear)[WB] is detectable
    *** cells: HEP3B<xPdpk1> in BMS "containing Tgfb1"
    *** enhanced by: xPdpk1(mnr)"KD" [substitution]
    *** source: 17327236-Fig-9d
  *** xSmad4[Ab] locatedin(subnuclear-bodies)[IHC] is increased itpo (xPias4 + xSumo1 + xUbe2i)
    *** cells: HELA in BMS
    *** partially inhibited by: xSmad4(K122R/K159R) [substitution]
    *** source: 12740389-Fig-4c
  *** xSmad4[Ab] locatedin(subnuclear-bodies)[IHC] is increased itpo (xPias4 + xSumo1)
    *** cells: HELA in BMS
    *** enhanced by: xUbe2i [addition]
    *** source: 12740389-Fig-4b
  *** rSmad4[Ab] nuc-import[IVnucImport] is unchanged by rSara(767-852)"SBD"
    *** cells: none
    *** comment: does not require cytosol
    *** source: 12917407-Fig-1a
  *** Smad4[Ab]IP STphos[pSTAb] is detectable
    *** cells: HEK293T in BMS
    *** reqs: Pdpk1 [RNAi]
    *** enhanced by: xPdpk1 [addition]
    *** inhibited by: xPdpk1(mnr)"KD" [addition]
    *** source: 17327236-Fig-1e
  *** xSmad4[Gal4-DBD] Gal4-reporter[Luc] is detectable
    *** cells: HACAT in BMS
    *** enhanced by: xSmad4(K113R/K159R) [substitution]
    *** enhanced by: xSmad4(K159R) [substitution]
    *** enhanced by: xSmad4(K113R) [substitution]
    *** source: 14750902-Fig-3c
  *** xSmad4[Gal4-DBD] Gal4-reporter[Luc] is detectable
    *** cells: MV1LUL17 in BMS
    *** enhanced by: xSmad4(K113R/K159R) [substitution]
    *** enhanced by: xSmad4(K159R) [substitution]
    *** enhanced by: xSmad4(K113R) [substitution]
    *** source: 14750902-Fig-3b
  *** xSmad4[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xSenp1
    *** cells: HACAT in BMS
    *** source: 14750902-Fig-3c
  *** xSmad4[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xMek1(del(32-51)/S218E/S222E)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-2a
  *** xSmad4[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xMekk1(380-672)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-2a
  *** xSmad4[tAb] copptby[WB] Pdpk1[Ab] is detectable
    *** cells: HEK293T in BMS
    *** source: 17327236-Fig-1b
  *** xSmad4[tAb] copptby[WB] xAtf2[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 10085140-Fig-3
  *** xSmad4[tAb] copptby[WB] xCdx2[tAb] is undetectable
    *** cells: COS in BMS
    *** source: 11741830-Fig-5a
  *** xSmad4[tAb] copptby[WB] xCtnnb1[tAb] is undetectable
    *** cells: COS in BMS
    *** source: 11741830-Fig-5a
  *** xSmad4[tAb] copptby[WB] xLkb1[tAb] is detectable
    *** cells: COS<xStk11ip> in BMS
    *** reqs: xStk11ip [omission]
    *** source: 11741830-Fig-5b
  *** xSmad4[tAb] copptby[WB] xLkb1[tAb] is undetectable
    *** cells: COS in BMS
    *** source: 11741830-Fig-5a
  *** xSmad4[tAb] copptby[WB] xLkb1[tAb] is undetectable
    *** cells: COS in BMS
    *** source: 11741830-Fig-5b
  *** xSmad4[tAb] copptby[WB] xPdpk1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 17327236-Fig-1a
  *** xSmad4[tAb] copptby[WB] xPias4[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 12904571-Fig-1b
  *** xSmad4[tAb] copptby[WB] xPias4[tAb] is increased itpo xSmad3
    *** cells: COS in BMS
    *** source: 12904571-Fig-2c
  *** xSmad4[tAb] copptby[WB] xPias4[tAb] is unchanged itpo xTgfbR1(T204D)"CA"
    *** cells: HEK293T in BMS
    *** source: 12904571-Fig-1c
  *** xSmad4[tAb] copptby[WB] xRbx1[tAb] is increased itpo xTgfbR1(T204D)"CA"
    *** cells: COS7 in BMS
    *** source: 11359933-Fig-2e
  *** xSmad4[tAb] copptby[WB] xSara[tAb] is undetectable
    *** cells: COS1 in BMS
    *** source: 9865696-Fig-2c
  *** xSmad4[tAb] copptby[WB] xSara[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 17272273-Fig-4a
  *** xSmad4[tAb] copptby[WB] xSmad2(T8D/T220D/S245D/S250D/S255D)[tAb] is detectable
    *** cells: COS7 in BMS
    *** inhibited by: xSmad2(WT) [substitution]
    *** source: 12193595-Fig-6a
  *** xSmad4[tAb] copptby[WB] xSmad2[tAb] is increased itpo xAcvR1b(T206D)"CA"
    *** cells: COS in BMS
    *** source: 9311995-Fig-5b
  *** xSmad4[tAb] copptby[WB] xSmad2[tAb] is increased itpo xMek1(S218E/S222D)"CA"
    *** cells: COS7 in BMS
    *** source: 12193595-Fig-6a
  *** xSmad4[tAb] copptby[WB] xSmad2[tAb] is increased itpo xMekk1(380-672)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-5b
  *** xSmad4[tAb] copptby[WB] xSmad2[tAb] is unchanged itpo xAcvR1(Q207D)"CA"
    *** cells: COS in BMS
    *** source: 9311995-Fig-5b
  *** xSmad4[tAb] copptby[WB] xSmad2[tAb] is unchanged itpo xAcvRl1(Q201D)"CA"
    *** cells: COS in BMS
    *** source: 9311995-Fig-5b
  *** xSmad4[tAb] copptby[WB] xSmad2[tAb] is unchanged itpo xBmpR1a(Q233D)"CA"
    *** cells: COS in BMS
    *** source: 9311995-Fig-5b
  *** xSmad4[tAb] copptby[WB] xSmad2[tAb] is unchanged itpo xBmpR1b(Q204D)"CA"
    *** cells: COS in BMS
    *** source: 9311995-Fig-5b
  *** xSmad4[tAb] copptby[WB] xSmad2[tAb] is unchanged itpo xEp300
    *** cells: HEK293T in BMS
    *** source: 17478422-Fig-6b
  *** xSmad4[tAb] copptby[WB] xSmad2[tAb] is unchanged itpo xMek1(del(32-51)/S218E/S222E)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-5b
  *** xSmad4[tAb] copptby[WB] xSmad2[tAb] is unchanged itpo xTak1(mnr)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-5b
  *** xSmad4[tAb] copptby[WB] xSmurf1(C710A)"CIA"[tAb] is undetectable
    *** cells: COS7 in BMS
    *** source: 11278251-Fig-1b
  *** xSmad4[tAb] copptby[WB] xSmurf2[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 11163210-Fig-1a
  *** xSmad4[tAb] copptby[WB] xStk11ip[tAb] is detectable
    *** cells: COS in BMS
    *** inhibited by: xStk11ip(2-318) [substitution]
    *** unaffected by: xStk11ip(313-1099) [substitution]
    *** source: 11741830-Fig-5a
  *** xSmad4[tAb] copptby[WB] xTgfbR1(mnr)"CA"[tAb] is detectable
    *** cells: COS1 in BMS
    *** inhibited by: xTgfbR1(WT) [substitution]
    *** source: 9346908-Fig-4
  *** xSmad4[tAb] copptby[WB] xTgfbR1(mnr)"CA"[tAb] is detectable
    *** cells: COS1<xSmad2> in BMS
    *** inhibited by: xSmad2(S464A) [substitution]
    *** inhibited by: xSmad2(S465A) [substitution]
    *** inhibited by: xSmad2(S467A) [substitution]
    *** inhibited by: xSmad2(S464A/S465A/S467A) [substitution]
    *** source: 9346908-Fig-5
  *** xSmad4[tAb] copptby[WB] xTgfbR1(mnr)"CA"[tAb] is detectable
    *** cells: HEPG2<xSmad2> in BMS
    *** inhibited by: xSmad2(S464A) [substitution]
    *** inhibited by: xSmad2(S465A) [substitution]
    *** inhibited by: xSmad2(S467A) [substitution]
    *** inhibited by: xSmad2(S464A/S465A/S467A) [substitution]
    *** source: 9346908-Fig-5
  *** xSmad4[tAb] copptby[WB] xTgfbRap1[tAb] is decreased itpo xTgfbR1(mnr)"CA"
    *** cells: COS1<xSmad2> in BMLS
    *** reqs: xSmad2 [omission]
    *** source: 12941698-Fig-5b
  *** xSmad4[tAb] copptby[WB] xTgfbRap1[tAb] is detectable
    *** cells: COS1 in BMLS
    *** unaffected by: xTgfbR1(mnr)"CA" [addition]
    *** source: 12941698-Fig-5b
  *** xSmad4[tAb] copptby[WB] xVps39[tAb] is decreased itpo xTgfbR1(mnr)"CA"
    *** cells: COS1 in BMLS
    *** enhanced by: xSmad2 [addition]
    *** source: 12941698-Fig-5a
  *** xSmad4[tAb] copptby[WB] xVps39[tAb] is detectable
    *** cells: COS1 in BMLS
    *** inhibited by: xTgfbR1(mnr)"CA" [addition]
    *** unaffected by: xSmad2 [addition]
    *** source: 12941698-Fig-5a
  *** xSmad4[tAb] copptby[WB] xXiap[GST] is undetectable
    *** cells: HEK293 in BMS
    *** source: 11356828-Fig-8
  *** xSmad4[tAb] copptby[WB] xZfyve16[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 17272273-Fig-4a
  *** xSmad4[tAb] locatedin(nucleus)[IHC] is increased itpo xMekk1(380-672)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-6a
  *** xSmad4[tAb] locatedin(nucleus)[IHC] is unchanged itpo xMek1(del(32-51)/S218E/S222E)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-6a
  *** xSmad4[tAb] oligo-binding[EMSA] is detectable
    *** cells: COS1<xTgfbR1(mnr)"CA"><xTgfbR2><xSmad3><xJun><xFos> in BMS
    *** oligo: AP1 5-CGCTTGATGAGTCAGCCGGAA-3
    *** source: 9732876-Fig-3f
  *** xSmad4[tAb] prot-exp[WB] is unchanged itpo xSmurf2
    *** cells: HEK293 in BMS
    *** source: 11016919-Fig-2
  *** xSmad4[tAb] prot-exp[WB] is unchanged itpo xSmurf2
    *** cells: HEK293T in BMS
    *** source: 11163210-Fig-1a
  *** xSmad4[tAb] snaggedby[WB] oligo[biotin] is detectable
    *** cells: COS1<xTgfbR1(mnr)"CA"><xTgfbR2> in BMS
    *** oligo: AP1 5-CGCTTGATGAGTCAGCCGGAA-3
    *** source: 9732876-Fig-3d
  *** xSmad4[tAb] snaggedby[WB] rNup214(1805-2091)[tAb] is undetectable
    *** cells: COS1 in BMS
    *** source: 12917407-Fig-6b
  *** xSmad4[tAb]IP acetyl[KAcAb] is unchanged itpo xEp300
    *** cells: HEK293T in BMS
    *** source: 17478422-Fig-1a
  *** xSmad4[tAb]IP prot-exp[WB] is detectable
    *** cells: HELA in BMS
    *** enhanced by: xSmad4(K159R/K113R) [substitution]
    *** source: 12621041-Fig-5c
  *** xSmad4[tAb]IP prot-exp[WB] is increased itpo xSumo1
    *** cells: HELA in BMS
    *** source: 12621041-Fig-5c
  *** xSmad4[tAb]IP prot-stability[35S-pulse-chase] is detectable
    *** cells: HELA in BMS
    *** enhanced by: xSmad4(K113R/K159R) [substitution]
    *** source: 12740389-Fig-5a
  *** xSmad4[tAb]IP Sphos[pSAb] is unchanged itpo xHgs
    *** cells: COS7<xAcvR2><xAcvR1b> in BMS
    *** source: 11094085(D)
  *** xSmad4[tAb]IP ubiq[tUbAb] is unchanged itpo xSmurf1
    *** cells: COS7<xUbiq> in BMS
    *** source: 11278251-Fig-3a
*** Smad5--
  *** Smad5[Ab] copptby[WB] Sptbn1[Ab] is undetectable
    *** cells: HEPG2 in BMS
    *** unaffected by: TgfbR1 (1 hr) [stim]
    *** source: 12543979-Fig-S2e
  *** xSmad5[tAb] copptby[WB] xSmurf1(C710A)"CIA"[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 11278251-Fig-1b
  *** xSmad5[tAb]IP acetyl[KAcAb] is unchanged itpo xEp300
    *** cells: HEK293T in BMS
    *** source: 17478422-Fig-1a
*** Smad6--
  *** xSmad6(mnr)"del-MH1"[tAb] copptby[WB] xSara[tAb] is undetectable
    *** cells: COS1 in BMS
    *** source: 9865696-Fig-2c
  *** xSmad6[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xMek1(del(32-51)/S218E/S222E)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-2a
  *** xSmad6[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xMekk1(380-672)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-2a
  *** xSmad6[tAb] copptby[WB] xSmurf1(C710A)"CIA"[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 11278251-Fig-1b
  *** xSmad6[tAb] copptby[WB] xStrap[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 10757800(D)
  *** xSmad6[tAb] copptby[WB] xZfyve16[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 17272273-Fig-4a
  *** xSmad6[tAb]IP acetyl[KAcAb] is unchanged itpo xEp300
    *** cells: HEK293T in BMS
    *** source: 17478422-Fig-1a
  *** xSmad6[tAb]IP sumo[tSuAb] is unchanged itpo xSumo1
    *** cells: HELA in BMS
    *** source: 12740389-Fig-1b
  *** xSmad6[tAb]IP sumo[tSuAb] is unchanged itpo xUbe2i
    *** cells: HELA<xSumo1> in BMS
    *** source: 12740389-Fig-3b
*** Smad7--
  *** Smad7-gene mRNA[RTPCR] is increased itao Adam17 [RNAi]
    *** cells: HACAT in BMLS
    *** source: 19595713-Fig-5d
  *** xSmad7(K64A)[tAb] prot-exp[WB] is increased itpo xEp300
    *** cells: HEK293T in BMS
    *** source: 12408818-Fig-5a
  *** xSmad7(K64A/K70A)[tAb] prot-exp[WB] is unchanged itpo xEp300
    *** cells: HEK293T in BMS
    *** source: 12408818-Fig-5a
  *** xSmad7(K70A)[tAb] prot-exp[WB] is unchanged itpo xEp300
    *** cells: HEK293T in BMS
    *** source: 12408818-Fig-5a
  *** xSmad7(TAD)[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xVps39
    *** cells: HEP3B in BMS
    *** source: 12941698-Fig-6h
  *** rSmad7[35S] boundby[WB] rHdac1[GST] is detectable
    *** cells: none
    *** source: 15831498-Fig-2b
  *** xSmad7[Ab] colocwith[IHC] Cav1[Ab] is detectable
    *** cells: MV1LU<xSmurf2(mnr)"CIA"> in BMS
    *** source: 12717440-Fig-4b
  *** xSmad7[Ab] colocwith[IHC] Eea1[Ab] is undetectable
    *** cells: MV1LU<xSmurf2(mnr)"CIA"> in BMS
    *** source: 12717440-Fig-4b
  *** Smad7[Ab] copptby[WB] Pdpk1[Ab] is detectable
    *** cells: HEK293T in BMS
    *** source: 17327236-Fig-1c
  *** Smad7[Ab] infraction(cytoplasmic)[WB] is detectable
    *** cells: HEP3B in BMS "containing Tgfb1"
    *** repressed by: Pdpk1 [RNAi]
    *** source: 17327236-Fig-9f
  *** Smad7[Ab] infraction(cytoplasmic)[WB] is detectable
    *** cells: HEP3B<xPdpk1> in BMS "containing Tgfb1"
    *** enhanced by: xPdpk1(mnr)"KD" [substitution]
    *** source: 17327236-Fig-9f
  *** Smad7[Ab] infraction(nuclear)[WB] is detectable
    *** cells: HEP3B in BMS "containing Tgfb1"
    *** reqs: Pdpk1 [RNAi]
    *** source: 17327236-Fig-9f
  *** Smad7[Ab] infraction(nuclear)[WB] is detectable
    *** cells: HEP3B<xPdpk1> in BMS "containing Tgfb1"
    *** inhibited by: xPdpk1(mnr)"KD" [substitution]
    *** source: 17327236-Fig-9f
  *** Smad7[Ab] prot-exp[WB] is increased itao Pdpk1 [RNAi]
    *** cells: HACAT in BMS "containing Tgfb1"
    *** source: 17327236-Fig-7d
  *** Smad7[Ab] prot-exp[WB] is increased itao Pdpk1 [RNAi]
    *** cells: HELA in BMS "containing Tgfb1"
    *** source: 17327236-Fig-7d
  *** Smad7[Ab]IP acetyl(K64)[AcAb] is increased itao Hdac1 [RNAi]
    *** cells: HEPG2 in BMS
    *** comment: Smad7 prot-expression is also repressed
    *** source: 15831498-Fig-6b
  *** xSmad7[Ab]IP phos[32Pi] is unchanged itpo xAcvR1b(mnr)"CA"
    *** cells: COS1 in BMS
    *** source: 9335507-Fig-4a
  *** xSmad7[Ab]IP ubiq[tUbAb] is increased itpo (xTgfbR1 + xTgfbR2)
    *** cells: HEK293T<xUbiq> in BMS
    *** enhanced by: xSmurf2 [addition]
    *** inhibited by: xSmurf2(C716A)"DN" [addition]
    *** comment: Smad7 ppt was boiled and reppt before WB
    *** source: 11163210-Fig-4e
  *** xSmad7[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xCtnnb1
    *** cells: HEPG2 in BMS
    *** enhanced by: xTcf7l2 [addition]
    *** source: 15684397-Fig-S2
  *** xSmad7[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xMek1(del(32-51)/S218E/S222E)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-2a
  *** xSmad7[Gal4-DBD] Gal4-reporter[Luc] is unchanged itpo xMekk1(380-672)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-2a
  *** xSmad7[tAb] copptby[WB] Pdpk1[Ab] is detectable
    *** cells: HEK293T in BMS
    *** source: 17327236-Fig-1b
  *** xSmad7[tAb] copptby[WB] xHdac1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xHdac1(1-160) [substitution]
    *** unaffected by: xHdac1(161-482) [substitution]
    *** inhibited by: xHdac1(321-482) [substitution]
    *** source: 15831498-Fig-3b
  *** xSmad7[tAb] copptby[WB] xHdac1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xSmad7(1-126) [substitution]
    *** inhibited by: xSmad7(127-260) [substitution]
    *** unaffected by: xSmad7(127-260) [substitution]
    *** source: 15831498-Fig-3a
  *** xSmad7[tAb] copptby[WB] xHdac1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15831498-Fig-2a
  *** xSmad7[tAb] copptby[WB] xHdac2[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15831498-Fig-2a
  *** xSmad7[tAb] copptby[WB] xHdac3[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15831498-Fig-2a
  *** xSmad7[tAb] copptby[WB] xHdac4[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15831498-Fig-2a
  *** xSmad7[tAb] copptby[WB] xHdac5[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15831498-Fig-2a
  *** xSmad7[tAb] copptby[WB] xHdac6[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15831498-Fig-2a
  *** xSmad7[tAb] copptby[WB] xPdpk1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 17327236-Fig-1a
  *** xSmad7[tAb] copptby[WB] xSara[tAb] is undetectable
    *** cells: COS1 in BMS
    *** source: 9865696-Fig-2c
  *** xSmad7[tAb] copptby[WB] xZfyve16[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 17272273-Fig-4a
  *** xSmad7[tAb] locatedin(cytoplasm)[IHC] is increased itpo xSmurf1
    *** cells: COS7 in BMS
    *** inhibited by: xSmad7(del(207-211))"PY-domain-deleted" [substitution]
    *** source: 11278251-Fig-2a
  *** xSmad7[tAb] locatedin(cytoplasm)[IHC] is increased itpo xSmurf1
    *** cells: COS7 in BMS
    *** unaffected by: Lactacystin [addition]
    *** unaffected by: MG132 [addition]
    *** source: 11278251-Fig-2b
  *** xSmad7[tAb] locatedin(cytoplasm)[IHC] is increased itpo xSmurf1(C710A)"CIA"
    *** cells: COS7 in BMS
    *** source: 11278251-Fig-2b
  *** xSmad7[tAb] locatedin(nucleus)[IHC] is unchanged itpo xMek1(del(32-51)/S218E/S222E)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-6a
  *** xSmad7[tAb] locatedin(nucleus)[IHC] is unchanged itpo xMekk1(380-672)"CA"
    *** cells: bAECs in BMS
    *** source: 10085121-Fig-6a
  *** xSmad7[tAb] prot-exp[WB] is decreased itpo xEp300(mnr)"HAT-deficient"
    *** cells: HEK293T in BMS
    *** source: 12408818-Fig-5e
  *** xSmad7[tAb] prot-exp[WB] is decreased itpo xEp300(mnr)"HAT-deficient"
    *** cells: HELA in BMS
    *** reversed by: xSmad7(K64A/K70A) [substitution]
    *** source: 12408818-Fig-7b
  *** xSmad7[tAb] prot-exp[WB] is decreased itpo xSmurf1
    *** cells: HEK293T in BMS
    *** reversed by: xEp300 [addition]
    *** source: 12408818-Fig-8b
  *** xSmad7[tAb] prot-exp[WB] is decreased itpo xSmurf1
    *** cells: HEK293T in BMS
    *** reversed by: xSmad7(K64A) [substitution]
    *** reversed by: xSmad7(K70A) [substitution]
    *** reversed by: xSmad7(K64A/K70A) [substitution]
    *** source: 12408818-Fig-8a
  *** xSmad7[tAb] prot-exp[WB] is decreased itpo xSmurf2
    *** cells: HEK293T<xTgfbR1(T204D)"CA"> in BMS
    *** reversed by: xSmurf2(C716A)"CIA" [substitution]
    *** source: 11163210-Fig-4b
  *** xSmad7[tAb] prot-exp[WB] is decreased itpo xSmurf2
    *** cells: HEK293T<xTgfbR1(T204D)"CA"> in BMS
    *** reversed by: xSmurf2(C716A)"ubiq-activity-mut" [substitution]
    *** source: 11163210(D)
  *** xSmad7[tAb] prot-exp[WB] is decreased itpo xSmurf2
    *** cells: HEK293T<xTgfbR1><xTgfbR2> in BMS
    *** reversed by: xSmurf2(C716A)"CIA" [substitution]
    *** source: 11163210-Fig-4b
  *** xSmad7[tAb] prot-exp[WB] is decreased itpo xSmurf2
    *** cells: HEK293T<xTgfbR2><xTgfbR1> in BMS
    *** reversed by: xSmurf2(C716A)"ubiq-activity-mut" [substitution]
    *** source: 11163210(D)
  *** xSmad7[tAb] prot-exp[WB] is decreased itpo xTgfbR1(mnr)"CA"
    *** cells: HEK293T in BMS
    *** reversed by: xEp300 [addition]
    *** source: 12408818-Fig-5d
  *** xSmad7[tAb] prot-exp[WB] is decreased itpo xTgfbR1(mnr)"CA"
    *** cells: HEK293T in BMS
    *** reversed by: xSmad7(K64A) [substitution]
    *** reversed by: xSmad7(K70A) [substitution]
    *** reversed by: xSmad7(K64A/K70A) [substitution]
    *** source: 12408818-Fig-5c
  *** xSmad7[tAb] prot-exp[WB] is detectable
    *** cells: HEK293T in BMS
    *** enhanced by: xSmad7(K64A) [substitution]
    *** comment: the prot-exp of xSmad7(K64A) is unaffected itpo xTgfbR1(mnr)"CA"
    *** comment: the prot-exp of xSmad7(K64A) is unaffected itpo xEp300
    *** source: 12408818-Fig-5d
  *** xSmad7[tAb] prot-exp[WB] is increased itao Hdac1 [RNAi]
    *** cells: HEPG2 in BMS
    *** source: 15831498-Fig-5b
  *** xSmad7[tAb] prot-exp[WB] is increased itpo xEp300
    *** cells: HEK293T in BMS
    *** inhibited by: xEp300(mnr)"HAT-deficient" [substitution]
    *** source: 12408818-Fig-5b
  *** xSmad7[tAb] prot-exp[WB] is increased itpo xEp300
    *** cells: HEK293T in BMS
    *** source: 12408818-Fig-5a
  *** xSmad7[tAb] prot-exp[WB] is unchanged itpo xEp300
    *** cells: HEK293T in BMS
    *** source: 12408818-Fig-5e
  *** xSmad7[tAb] prot-exp[WB] is unchanged itpo xEp300(mnr)"HAT-deficient"
    *** cells: HEK293T in BMS
    *** source: 12408818-Fig-5b
  *** xSmad7[tAb] prot-exp[WB] is unchanged itpo xSmurf2
    *** cells: HEK293T in BMS
    *** source: 11163210-Fig-1a
  *** xSmad7[tAb] prot-stability[35S-pulse-chase] is decreased itpo xSmurf2
    *** cells: COS1 in BMS
    *** source: 11163210-Fig-1b
  *** xSmad7[tAb]IP acetyl(K64)[AcAb] is increased itao Hdac1 [RNAi]
    *** cells: HEPG2 in BMS "treated with Tgfb1 (tnr)"
    *** source: 15831498-Fig-4c
  *** xSmad7[tAb]IP acetyl[KAcAb] is decreased itpo xHdac1
    *** cells: HEK293T<xEp300> in BMS
    *** source: 15831498-Fig-4a
  *** xSmad7[tAb]IP acetyl[KAcAb] is decreased itpo xHdac3
    *** cells: HEK293T<xEp300> in BMS
    *** source: 15831498-Fig-4a
  *** xSmad7[tAb]IP acetyl[KAcAb] is decreased itpo xHdac4
    *** cells: HEK293T<xEp300> in BMS
    *** source: 15831498-Fig-4a
  *** xSmad7[tAb]IP acetyl[KAcAb] is decreased itpo xHdac5
    *** cells: HEK293T<xEp300> in BMS
    *** source: 15831498-Fig-4a
  *** xSmad7[tAb]IP acetyl[KAcAb] is unchanged itpo xCbp
    *** cells: HEK293T in BMS
    *** source: 12408818-Fig-2a
  *** xSmad7[tAb]IP acetyl[KAcAb] is unchanged itpo xHdac2
    *** cells: HEK293T<xEp300> in BMS
    *** source: 15831498-Fig-4a
  *** xSmad7[tAb]IP acetyl[KAcAb] is unchanged itpo xPcaf
    *** cells: HEK293T in BMS
    *** source: 12408818-Fig-2a
  *** xSmad7[tAb]IP acetyl[KAcAb] is unchanged itpo xTgfbR1(mnr)"CA"
    *** cells: HEK293T in BMS
    *** source: 12408818-Fig-2a
  *** xSmad7[tAb]IP prot-exp[WB] is detectable
    *** cells: HEPG2 in BMS "treated with Tgfb1 (tnr)"
    *** unaffected by: Hdac1 [RNAi]
    *** source: 15831498-Fig-4c
  *** xSmad7[tAb]IP prot-stability[35S-pulse-chase] is decreased itpo xTgfbR1(mnr)"CA"
    *** cells: COS7 in BMS
    *** reversed by: xSmad7(K64A) [substitution]
    *** reversed by: xSmad7(K70A) [substitution]
    *** source: 12408818-Fig-6
  *** xSmad7[tAb]IP sumo[tSuAb] is unchanged itpo xSumo1
    *** cells: HELA in BMS
    *** source: 12740389-Fig-1b
  *** xSmad7[tAb]IP sumo[tSuAb] is unchanged itpo xUbe2i
    *** cells: HELA<xSumo1> in BMS
    *** source: 12740389-Fig-3b
  *** xSmad7[tAb]IP ubiq[tUbAb] is increased itpo xHdac1
    *** cells: HEK293T<xUbiq> in BMS
    *** source: 15831498-Fig-5c
  *** rSmad7[UbAb] ubiq[UbAb] is increased by rUbiq
    *** cells: none
    *** comment: Rabbit Reticulocyte Lysate is added as a source of ubiquitination machinery
    *** inhibited by: rEp300(1135-1810)"HAT-domain" [addition]
    *** source: 12408818-Fig-5f
  *** rSmad7[UbAb] ubiq[UbAb] is increased by rUbiq
    *** cells: none
    *** comment: Rabbit Reticulocyte Lysate is added as a source of ubiquitination machinery
    *** inhibited by: rSmad7(K64A/K70A) [substitution]
    *** source: 12408818-Fig-5f
*** Smad9--
  *** xSmad9[tAb] copptby[WB] xSmurf1(C710A)"CIA"[tAb] is undetectable
    *** cells: COS7 in BMS
    *** source: 11278251-Fig-1b
  *** xSmad9[tAb]IP phos[32Pi] is increased itpo xAcvR1(Q207D)"CA"
    *** cells: COS1 in BMS
    *** inhibited by: xAcvR1(WT) [substitution]
    *** source: 9748228(D)
*** Smad23s--
  *** Smad23s[Ab] boundto(Pai1-gene)[ChIP] is increased itpo xEts1
    *** cells: HEK293T<xTgfbR1(mnr)"CA"> in BMS
    *** source: 18955504-Fig-4g
  *** Smad23s[Ab] boundto(Pai1-gene)[ChIP] is unchanged itpo xJun
    *** cells: HEK293T<xTgfbR1(mnr)"CA"> in BMS
    *** source: 18955504-Fig-4g
  *** Smad23s[Ab] boundto(Pai1-gene)[ChIP] is unchanged itpo xTfap2a
    *** cells: HEK293T<xTgfbR1(mnr)"CA"> in BMS
    *** source: 18955504-Fig-4g
  *** Smad23s[Ab] boundto(Pai1-gene)[ChIP] is unchanged itpo xTgfbR1(mnr)"CA"
    *** cells: HEK293T in BMS
    *** source: 18955504-Fig-4g
  *** Smad23s[Ab] copptby[WB] Ets1[Ab] is undetectable
    *** cells: HACAT in BMS
    *** unaffected by: Tgfb1 (90 min) [stim]
    *** source: 18955504-Fig-S5a
  *** Smad23s[Ab] copptby[WB] Jun[Ab] is undetectable
    *** cells: HACAT in BMS
    *** unaffected by: Tgfb1 (90 min) [stim]
    *** source: 18955504-Fig-S5a
  *** Smad23s[Ab] locatedin(nucleus)[IHC] is decreased itpo xHras(G12V)"CA"
    *** cells: COLO205 in BMS "treated with Tgfb1 for 30 min"
    *** source: 10197981-Table-1
  *** Smad23s[Ab] locatedin(nucleus)[IHC] is decreased itpo xHras(G12V)"CA"
    *** cells: HT29 in BMS "treated with Tgfb1 for 30 min"
    *** source: 10197981-Table-1
  *** Smad23s[Ab] locatedin(nucleus)[IHC] is decreased itpo xHras(G12V)"CA"
    *** cells: MV1LU in BMS "treated with Tgfb1 for 30 min"
    *** source: 10197981-Fig-3
  *** Smad23s[Ab] locatedin(nucleus)[IHC] is decreased itpo xMek1(mnr)"CA"
    *** cells: MV1LU in BMS "treated with Tgfb1 for 30 min"
    *** source: 10197981-Fig-3
  *** Smad23s[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: HELA in BMS "treated with Tgfb1 for 1 hr"
    *** inhibited by: xDnm1(K44E)"DN" [addition]
    *** source: 12356868-Fig-3
  *** Smad23s[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: SW620 in BMS "treated with Tgfb1 for 30 min"
    *** comment: SW620 contain a Kras(G12V) mutation
    *** source: 10197981-Table-1
  *** Smad23s[Ab] locatedin(nucleus)[IHC] is undetectable
    *** cells: DLD1 in BMS "treated with Tgfb1 for 30 min"
    *** comment: DLD1 contain a Kras(G13D) mutation
    *** source: 10197981-Table-1
  *** Smad23s[Ab] locatedin(nucleus)[IHC] is undetectable
    *** cells: LOVO in BMS "treated with Tgfb1 for 30 min"
    *** comment: LOVO contain a Kras(G12D) mutation
    *** source: 10197981-Table-1
  *** xSmc1a[tAb] copptby[WB] xSmc3[tAb] is detectable
    *** cells: HEK293<xSmc1a><xSmc3> in BMS
    *** unaffected by: xSmc1a(S957A) [substitution]
    *** unaffected by: xSmc1a(S966A) [substitution]
    *** unaffected by: xSmc1a(S957A/S966A) [substitution]
    *** source: 11877376-Fig-4b
  *** xSmc1a[tAb] copptby[WB] xSmc3[tAb] is detectable-but unchanged irt IR (2 hr)
    *** cells: HEK293<xSmc1a><xSmc3> in BMS
    *** source: 11877376-Fig-4b
  *** xSmc3[tAb] copptby[WB] xSmc1a[tAb] is detectable
    *** cells: HEK293<xSmc1a><xSmc3> in BMS
    *** unaffected by: xSmc1a(S957A) [substitution]
    *** unaffected by: xSmc1a(S966A) [substitution]
    *** unaffected by: xSmc1a(S957A/S966A) [substitution]
    *** source: 11877376-Fig-4b
  *** xSmc3[tAb] copptby[WB] xSmc1a[tAb] is detectable-but unchanged irt IR (2 hr)
    *** cells: HEK293<xSmc1a><xSmc3> in BMS
    *** source: 11877376-Fig-4b
  *** xSmurf1(I638A/L640A)"NES-mut"[tAb] locatedin(nucleus)[IHC] is detectable
    *** cells: HELA in BMS
    *** unaffected by: xCrm1 [addition]
    *** source: 12519765-Fig-4a,4b
  *** xSmurf1[tAb] locatedin(cytoplasm)[IHC] is detectable
    *** cells: COS7<xSmad7> in BMS
    *** source: 11278251-Fig-2b
  *** xSmurf1[tAb] locatedin(nucleus)[IHC] is decreased itpo xCrm1
    *** cells: HELA in BMS
    *** reversed by: LMB [addition]
    *** source: 12519765-Fig-1f
  *** xSmurf1[tAb] locatedin(nucleus)[IHC] is detectable
    *** cells: HELA<xSmad7> in BMS
    *** unaffected by: xSmurf1(I638A/L640A)"NES-mut" [substitution]
    *** source: 12519765-Fig-4d
  *** xSmurf2(248-369)[tAb] copptby[WB] xSmad1[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 11158580-Fig-2a
  *** xSmurf2(248-369)[tAb] copptby[WB] xSmad3[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 11158580-Fig-2a
  *** xSmurf2(248-369)[tAb] copptby[WB] xSmad4[tAb] is undetectable
    *** cells: COS1 in BMS
    *** source: 11158580-Fig-2a
  *** rSmurf2[35S] boundby[WB] rSmad1[GST] is detectable
    *** cells: none
    *** source: 11016919-Fig-1b
  *** rSmurf2[35S] boundby[WB] rSmad3[GST] is detectable
    *** cells: none
    *** source: 11016919-Fig-1b
  *** rSmurf2[35S] boundby[WB] rSmad4[GST] is undetectable
    *** cells: none
    *** source: 11016919-Fig-1b
  *** xSmurf2[tAb] copptby[WB] xSmad1[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 11158580-Fig-2a
  *** xSmurf2[tAb] copptby[WB] xSmad3[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 11158580-Fig-2a
  *** xSmurf2[tAb] copptby[WB] xSmad4[tAb] is undetectable
    *** cells: COS1 in BMS
    *** source: 11158580-Fig-2a
  *** xSnx1[tAb] copptby[WB] TfRc[Ab] is detectable
    *** cells: COS7 in BMS
    *** source: 9819414(D)
  *** xSnx1[tAb] copptby[WB] xEgfR[Ab] is detectable
    *** cells: COS7 in BMS
    *** source: 9819414(D)
  *** xSnx1[tAb] copptby[WB] xInsR[Ab] is detectable
    *** cells: COS7 in BMS
    *** source: 9819414(D)
  *** xSnx1[tAb] copptby[WB] xLepRa[Ab] is undetectable
    *** cells: COS7 in BMS
    *** source: 9819414(D)
  *** xSnx1[tAb] copptby[WB] xLepRb[Ab] is detectable
    *** cells: COS7 in BMS
    *** source: 9819414(D)
  *** xSnx1[tAb] copptby[WB] xPdgfR[Ab] is detectable
    *** cells: COS7 in BMS
    *** source: 9819414(D)
  *** xSnx1[tAb] copptby[WB] xSnx2[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 9819414(D)
  *** xSnx1[tAb] copptby[WB] xSnx6[tAb] is detectable
    *** cells: COS1 in BMLS
    *** source: 11279102(D)
  *** xSnx1a[tAb] copptby[WB] TfRc[Ab] is detectable
    *** cells: COS7 in BMS
    *** source: 9819414(D)
  *** xSnx1a[tAb] copptby[WB] xEgfR[Ab] is detectable
    *** cells: COS7 in BMS
    *** source: 9819414(D)
  *** xSnx1a[tAb] copptby[WB] xInsR[Ab] is detectable
    *** cells: COS7 in BMS
    *** source: 9819414(D)
  *** xSnx1a[tAb] copptby[WB] xLepRa[Ab] is undetectable
    *** cells: COS7 in BMS
    *** source: 9819414(D)
  *** xSnx1a[tAb] copptby[WB] xLepRb[Ab] is detectable
    *** cells: COS7 in BMS
    *** source: 9819414(D)
  *** xSnx1a[tAb] copptby[WB] xPdgfR[Ab] is detectable
    *** cells: COS7 in BMS
    *** source: 9819414(D)
  *** xSnx1a[tAb] copptby[WB] xSnx2[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 9819414(D)
  *** xSnx2[tAb] copptby[WB] TfRc[Ab] is undetectable
    *** cells: COS7 in BMS
    *** source: 9819414(D)
  *** xSnx2[tAb] copptby[WB] xEgfR[Ab] is detectable
    *** cells: COS7 in BMS
    *** source: 9819414(D)
  *** xSnx2[tAb] copptby[WB] xInsR[Ab] is detectable
    *** cells: COS7 in BMS
    *** source: 9819414(D)
  *** xSnx2[tAb] copptby[WB] xLepRa[Ab] is undetectable
    *** cells: COS7 in BMS
    *** source: 9819414(D)
  *** xSnx2[tAb] copptby[WB] xLepRb[Ab] is detectable
    *** cells: COS7 in BMS
    *** source: 9819414(D)
  *** xSnx2[tAb] copptby[WB] xPdgfR[Ab] is detectable
    *** cells: COS7 in BMS
    *** source: 9819414(D)
  *** xSnx2[tAb] copptby[WB] xSnx2[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 9819414(D)
  *** xSnx2[tAb] copptby[WB] xSnx6[tAb] is detectable
    *** cells: COS1 in BMLS
    *** source: 11279102(D)
  *** xSnx3[tAb] copptby[WB] TfRc[Ab] is undetectable
    *** cells: COS7 in BMS
    *** source: 9819414(D)
  *** xSnx3[tAb] copptby[WB] xEgfR[Ab] is undetectable
    *** cells: COS7 in BMS
    *** source: 9819414(D)
  *** xSnx3[tAb] copptby[WB] xInsR[Ab] is undetectable
    *** cells: COS7 in BMS
    *** source: 9819414(D)
  *** xSnx3[tAb] copptby[WB] xLepRa[Ab] is undetectable
    *** cells: COS7 in BMS
    *** source: 9819414(D)
  *** xSnx3[tAb] copptby[WB] xLepRb[Ab] is undetectable
    *** cells: COS7 in BMS
    *** source: 9819414(D)
  *** xSnx3[tAb] copptby[WB] xPdgfR[Ab] is undetectable
    *** cells: COS7 in BMS
    *** source: 9819414(D)
  *** xSnx3[tAb] copptby[WB] xSnx2[tAb] is undetectable
    *** cells: COS7 in BMS
    *** source: 9819414(D)
  *** xSnx3[tAb] copptby[WB] xSnx6[tAb] is undetectable
    *** cells: COS1 in BMLS
    *** source: 11279102(D)
  *** xSnx4[tAb] copptby[WB] TfRc[Ab] is undetectable
    *** cells: COS7 in BMS
    *** source: 9819414(D)
  *** xSnx4[tAb] copptby[WB] xEgfR[Ab] is detectable
    *** cells: COS7 in BMS
    *** source: 9819414(D)
  *** xSnx4[tAb] copptby[WB] xInsR[Ab] is undetectable
    *** cells: COS7 in BMS
    *** source: 9819414(D)
  *** xSnx4[tAb] copptby[WB] xLepRa[Ab] is undetectable
    *** cells: COS7 in BMS
    *** source: 9819414(D)
  *** xSnx4[tAb] copptby[WB] xLepRb[Ab] is detectable
    *** cells: COS7 in BMS
    *** source: 9819414(D)
  *** xSnx4[tAb] copptby[WB] xPdgfR[Ab] is detectable
    *** cells: COS7 in BMS
    *** source: 9819414(D)
  *** xSnx4[tAb] copptby[WB] xSnx2[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 9819414(D)
  *** xSnx4[tAb] copptby[WB] xSnx6[tAb] is detectable
    *** cells: COS1 in BMLS
    *** source: 11279102(D)
  *** xSnx6[tAb] oligomerization[2TagPpt] is detectable
    *** cells: COS1 in BMLS
    *** source: 11279102(D)
  *** xSocs1[tAb] copptby[WB] xEgfR[tAb] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: Egf (2 hr) [stim]
    *** source: 12070153-Fig-5b
  *** xSocs1[tAb] copptby[WB] xIrak1[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 12433373-Fig-7b
  *** xSocs1[tAb] copptby[WB] xJak2[Ab] is detectable
    *** cells: HEK293T in BMS
    *** source: 9202126-Fig-3b
  *** xSocs1[tAb] copptby[WB] xRela[tAb] is detectable
    *** cells: mEFs in BMS
    *** source: 14690596-Fig-7c
  *** xSocs1[tAb] copptby[WB] xStat1[tAb] is detectable
    *** cells: U3A<Stat1~null> in BMS
    *** unaffected by: xStat1(K410Q/K413Q) [substitution]
    *** source: 19171783-Fig-S3b
  *** xSocs2[Ab] copptby[WB] xSocs3[Ab] is detectable
    *** cells: HEK293T in BMS "treated with IL3 for 2 hr"
    *** source: 16199887-Fig-7b
*** Socs3--
  *** Socs3-gene mRNA[RTPCR] is detectable
    *** cells: mSpCD4TCs in BMS "pretreated with anti-Cd3 + anti-Cd28 + IL12 for 5 days"
    *** does not req: Stat6 [KO]
    *** does not req: Tbet [KO]
    *** source: 19324016-Fig-3c
  *** xSocs3[Ab] copptby[WB] xPeli2[tAb] is detectable
    *** cells: RAW2647 in BMS "treated with Lps (30 min)"
    *** source: 15213237-Fig-9b
  *** xSocs3[Ab]IP Yphos[pYAb] is detectable
    *** cells: HEK293<xJak1> in BMS
    *** unaffected by: xIL2Rb [addition]
    *** source: 10373548-Fig-2b
  *** xSocs3[Ab]IP Yphos[pYAb] is detectable
    *** cells: HEK293<xJak3> in BMS
    *** inhibited by: xIL2Rb [addition]
    *** source: 10373548-Fig-2b
  *** xSocs3[tAb] copptby[WB] xEgfR[tAb] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: Egf (2 hr) [stim]
    *** source: 12070153-Fig-5b
  *** xSocs3[tAb] copptby[WB] xJak1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xSocs3(Y31F) [substitution]
    *** unaffected by: xSocs3(Y204F) [substitution]
    *** unaffected by: xSocs3(Y221F) [substitution]
    *** unaffected by: xSocs3(Y204F/Y221F) [substitution]
    *** unaffected by: xSocs3(mnr)"del-socs-box" [substitution]
    *** source: 11331873-Fig-1d
  *** xSocs3[tAb] prot-exp[WB] is decreased itpo xSocs2
    *** cells: HEK293T in BMS
    *** enhanced by: xTceb1 + xTceb2 [addition]
    *** source: 16199887-Fig-6c
  *** xSocs3[tAb] prot-exp[WB] is decreased itpo xSocs2
    *** cells: HEK293T in BMS
    *** reversed by: MG132 + ALLN [addition]
    *** source: 16199887-Fig-6c
  *** xSocs3[tAb] prot-exp[WB] is decreased itpo xSocs2
    *** cells: HEK293T in BMS
    *** reversed by: xSocs2(mnr)"del-dSB" [substitution]
    *** source: 16199887-Fig-6a
  *** xSocs3[tAb] prot-exp[WB] is decreased itpo xSocs2
    *** cells: HEK293T in BMS
    *** reversed by: xSocs2(mnr)"del-dSB" [substitution]
    *** source: 16199887-Fig-6c
  *** xSocs3[tAb] snaggedby[WB] xSocs2[His] is detectable
    *** cells: HEK293T in BMS
    *** source: 16199887-Fig-7a
  *** xSocs3[tAb]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: HEK293<xJak1> in BMS
    *** inhibited by: xIL2Rb [addition]
    *** source: 10373548-Fig-2e
  *** xSocs3[tAb]IP Yphos[pYAb] is detectable
    *** cells: HEK293T<xJak1> in BMS
    *** unaffected by: xSocs3(Y31F) [substitution]
    *** unaffected by: xSocs3(Y204F) [substitution]
    *** unaffected by: xSocs3(Y165F/Y166F/Y167F) [substitution]
    *** unaffected by: xSocs3(Y221F) [substitution]
    *** inhibited by: xSocs3(Y204F/Y221F) [substitution]
    *** source: 11331873-Fig-1c
  *** xSocs3[tAb]IP Yphos[pYAb] is increased itpo xJak1
    *** cells: HEK293T in BMS
    *** source: 11331873-Fig-3a
  *** xSocs3[tAb]IP Yphos[pYAb] is increased itpo xJak2
    *** cells: HEK293T in BMS
    *** source: 11331873-Fig-3a
*** Sos1--
  *** xSos1[Ab] copptby[WB] xGrb2[Ab] is decreased itpo xShc1p66
    *** cells: mEFs<Shc1p66~null> in BMS
    *** source: 16520382-Fig-2b
  *** xSos1[Ab] copptby[WB] xGrb2[Ab] is detectable
    *** cells: HEK293<xEgfR><xSos1><xGrb2> in BMS
    *** source: 8479541-Fig-1a
  *** xSos1[Ab] copptby[WB] xGrb2[Ab] is increased itao Shc1p66 [KO]
    *** cells: mEFs in BMS
    *** source: 16520382-Fig-2b
  *** xSos1[tAb] snaggedby[WB] rCdc42{NucFree}[GST] is undetectable
    *** cells: mEFs<Eps8~null><xEps8> in BMS
    *** source: 11777939-Fig-7c
*** Sos2--
  *** Sos2[Ab] copptby[WB] Shc1[Ab] is increased itpo xSrc(mnr)"vSrc"
    *** cells: mEFs in BMS
    *** partially repressed by: Sos1 [KO]
    *** source: 10675333-Fig-10b
  *** Sos2[Ab] copptby[WB] xSrc(mnr)"vSrc"[Ab] is undetectable
    *** cells: mEFs<Sos1~null> in BMS
    *** source: 10675333-Fig-10b
  *** Sp1[Ab] copptby[WB] Myc[Ab] is undetectable
    *** cells: HEK293 in BMS
    *** source: 20008325-Fig-1d
  *** Sp1[Ab] oligo-binding[ELISA] is unchanged itpo (xIL12a + xIL12b) 
    *** cells: TC71 in BMS
    *** source: 16380506-Fig-7a
  *** xSphk2[tAb] copptby[WB] xIL12Rb1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 12874225-Fig-1
  *** xSpry2[tAb]IP Yphos[pYAb] is increased itpo xFgfR1
    *** cells: HEK293T<xSpry2> in BMS
    *** partially inhibited by: xSpry2(Y55F) [substitution]
    *** source: 12815057-Fig-1c
  *** xSpry2[tAb]IP Yphos[pYAb] is increased itpo xFgfR1
    *** cells: HEK293T<xSpry2> in BMS
    *** partially inhibited by: xSpry2(Y55F) [substitution]
    *** unaffected by: xSpry2(Y176F) [substitution]
    *** unaffected by: xSpry2(Y215F) [substitution]
    *** unaffected by: xSpry2(Y283F) [substitution]
    *** source: 12815057-Fig-1b
  *** xSpry2[tAb]IP Yphos[pYAb] is increased itpo xFgfR1
    *** cells: HEK293T<xSpry2> in BMS
    *** unaffected by: xSpry2(T52A) [substitution]
    *** unaffected by: xSpry2(N53A) [substitution]
    *** unaffected by: xSpry2(E54A) [substitution]
    *** inhibited by: xSpry2(Y55A) [substitution]
    *** unaffected by: xSpry2(T56A) [substitution]
    *** unaffected by: xSpry2(E57A) [substitution]
    *** unaffected by: xSpry2(G58A) [substitution]
    *** unaffected by: xSpry2(P59A) [substitution]
    *** source: 12815057-Fig-2c
*** Sptbn1--
  *** Sptbn1[Ab] copptby[WB] Sara[Ab] is undetectable
    *** cells: HEPG2 in BMS
    *** unaffected by: TgfbR1 (1 hr) [stim]
    *** source: 12543979-Fig-S2d
  *** Sptbn1[Ab] copptby[WB] Smad1[Ab] is undetectable
    *** cells: HEPG2 in BMS
    *** unaffected by: TgfbR1 (1 hr) [stim]
    *** source: 12543979-Fig-S2d
  *** Sptbn1[Ab] copptby[WB] Smad2[Ab] is undetectable
    *** cells: HEPG2 in BMS
    *** unaffected by: TgfbR1 (1 hr) [stim]
    *** source: 12543979-Fig-2
  *** Sptbn1[Ab] copptby[WB] Smad3[Ab] is detectable
    *** cells: HEPG2 in BMS
    *** source: 12543979-Fig-2
  *** Sptbn1[Ab] copptby[WB] Smad4[Ab] is undetectable
    *** cells: HEPG2 in BMS
    *** source: 12543979-Fig-2
  *** Sptbn1[Ab] copptby[WB] Smad5[Ab] is undetectable
    *** cells: HEPG2 in BMS
    *** unaffected by: TgfbR1 (1 hr) [stim]
    *** source: 12543979-Fig-S2d
  *** Sptbn1[Ab] copptby[WB] TgfbR1[Ab] is detectable
    *** cells: HEPG2 in BMS
    *** source: 12543979-Fig-2
  *** xSqstm1[Ab] copptby[WB] xZnf274[Ab] is detectable
    *** cells: HEK293<xSqstm1><xTraf6><xZnf274><xUbiq> in BMS
    *** unaffected by: xSqstm1(mnr)"del-Nterm" [substitution]
    *** inhibited by: xSqstm1(mnr)"del-UBA" [substitution]
    *** source: 16252010-Fig-5d
  *** xSqstm1[tAb] copptby[WB] xIkk2[tAb] is increased itpo xPkcz
    *** cells: HEK293<xPkcz> in BMS
    *** source: 10356400-Fig-7b
  *** xSqstm1[tAb] copptby[WB] xRipk1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 10356400-Fig-3a,3c
  *** xSqstm1[tAb] copptby[WB] xTraf2[tAb] is increased itpo xRipk1
    *** cells: HEK293<xRipk1> in BMS
    *** source: 10356400-Fig-3c
  *** xSqstm1[tAb] copptby[WB] xTraf2[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 10356400-Fig-3b
  *** xSqstm1[tAb] copptby[WB] xTraf2[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 10747026-Fig-4b
  *** xSqstm1[tAb] copptby[WB] xTraf5[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 10747026-Fig-4a
  *** xSqstm1[tAb] copptby[WB] xTraf6[tAb] is detectable
    *** cells: HEK293 in BMS
    *** enhanced by: xTraf6(mnr)"Cterm" [substitution]
    *** source: 10747026-Fig-11
  *** xSqstm1[tAb] copptby[WB] xTraf6[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 10747026-Fig-4a
  *** xSqstm1[tAb] copptby[WB] xTraf6[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 10747026-Fig-5
*** Src--
  *** rSrc[35S] boundby[WB] rNckipsd(159-348)[GST] is detectable
    *** cells: none
    *** source: 14765113-Fig-2c
  *** rSrc[35S] boundby[WB] rNckipsd(mnr)"Cterm"[GST] is undetectable
    *** cells: none
    *** source: 14765113-Fig-2c
  *** rSrc[35S] boundby[WB] rNckipsd(mnr)"SH3"[GST] is undetectable
    *** cells: none
    *** source: 14765113-Fig-2c
  *** Src[Ab] copptby[WB] xFak2[tAb] is detectable
    *** cells: COS7<xFak2> in BMS
    *** inhibited by: xFak2(Y402F) [substitution]
    *** inhibited by: xFak2(K457R) [substitution]
    *** source: 9242628-Fig-4b
  *** Src[Ab] copptby[WB] xGab2[Ab] is detectable
    *** cells: rHepatocytes in BMLS
    *** inhibited by: xGab2(del(348-355)) [substitution]
    *** source: 12464621-Fig-4b
  *** Src[Ab] copptby[WB] xGab2[Ab] is detectable
    *** cells: rHepatocytes in BMLS
    *** unaffected by: Egf (1 min) [stim]
    *** source: 12464621-Fig-4b
  *** Src[Ab] infraction(membrane)[WB] is detectable
    *** cells: HELA in BMS
    *** does not req: Nckipsd [RNAi]
    *** source: 14765113-Fig-6b
  *** Src[Ab] prot-exp[WB] is detectable
    *** cells: HELA in BMS
    *** does not req: Nckipsd [RNAi]
    *** source: 14765113-Fig-6b
  *** Src[Ab]IP IVKA(auto)[32P-ATP] is decreased itpo xGab1(Y627F/Y659F)
    *** cells: MDAMB468 in BMLS
    *** source: 14665621-Fig-6a
  *** Src[Ab]IP IVKA(auto)[32P-ATP] is increased itpo xShp2
    *** cells: mEFs<Shp2~null> in BMLS
    *** unaffected by: Egf (5 min) [stim]
    *** source: 14967142-Fig-1c
  *** Src[Ab]IP IVKA(auto)[32P-ATP] is unchanged itpo xShp2(C459S/D425A)"CIA"
    *** cells: MDAMB468 in BMLS
    *** source: 14665621-Fig-6b
  *** Src[Ab]IP IVKA(Enolase)[32P-ATP] is increased itpo xHras(G12V/E37G)
    *** cells: HEK293 in BMS
    *** source: 10675331-Fig-2c
  *** Src[Ab]IP IVKA(Enolase)[32P-ATP] is increased itpo xHras(Q61L)"CA"
    *** cells: HEK293 in BMS
    *** source: 10675331-Fig-2c
  *** Src[Ab]IP IVKA(Enolase)[32P-ATP] is increased itpo xRala(Q72L)"CA"
    *** cells: 3Y1<xEgfR> in BMLS
    *** source: 10675331-Fig-2b
  *** Src[Ab]IP IVKA(Enolase)[32P-ATP] is increased itpo xRala(Q72L)"CA"
    *** cells: HEK293 in BMLS
    *** source: 10675331-Fig-2a
  *** Src[Ab]IP IVKA(Enolase)[32P-ATP] is increased itpo xRgl4
    *** cells: HEK293 in BMLS
    *** source: 10675331-Fig-2a
  *** Src[Ab]IP IVKA(Enolase)[32P-ATP] is increased itpo xShp2
    *** cells: mEFs<Shp2~null> in BMLS
    *** source: 14967142-Fig-1c
  *** Src[Ab]IP IVKA(Enolase)[32P-ATP] is unchanged itpo xHras(G12V/T35S)
    *** cells: HEK293 in BMS
    *** source: 10675331-Fig-2c
  *** Src[Ab]IP IVKA(Gab1)[32P-ATP] is decreased itpo xGab1(Y627F/Y659F)
    *** cells: MDAMB468 in BMLS
    *** source: 14665621-Fig-6a
  *** Src[Ab]IP IVKA(Gab1)[32P-ATP] is unchanged itpo xShp2(C459S/D425A)"CIA"
    *** cells: MDAMB468 in BMLS
    *** source: 14665621-Fig-6b
  *** xSrc[Ab]IP IVKA(Khdrbs1)[32P-ATP] is increased itpo xStat3
    *** cells: RAT2 in BMS
    *** source: 12244095-Fig-6
  *** Src[Ab]IP phos(Y530)[phosAb] is unchanged itpo xGab1(Y627F/Y659F)
    *** cells: MDAMB468 in BMLS
    *** comment: Src IP is with anti-Pxn Ab
    *** source: 14665621-Fig-7c
  *** Src[Ab]IP Yphos[pYAb] is increased itpo xFak2
    *** cells: COS7 in BMS
    *** inhibited by: xFak2(Y402F) [substitution]
    *** inhibited by: xFak2(K457R) [substitution]
    *** source: 9242628-Fig-4a
  *** Src[phosAb] phos(Y419)[phosAb] is detectable
    *** cells: mEFs in BMLS
    *** reqs: Shp2 [KO]
    *** source: 14967142-Fig-1a
  *** Src[phosAb] phos(Y419)[phosAb] is detectable
    *** cells: mEFs in BMLS
    *** reqs: Shp2 [KO]
    *** source: 14967142-Fig-3b
  *** Src[phosAb] phos(Y419)[phosAb] is increased itao Csk [KO]
    *** cells: mEFs<xGab2> in BMLS
    *** source: 12464621-Fig-2a
  *** Src[phosAb] phos(Y419)[phosAb] is increased itpo xCrk
    *** cells: HEK293T in BMS
    *** partially inhibited by: xGab1 [addition]
    *** partially inhibited by: xGab1(del(241-411)) [addition]
    *** source: 19350053-Fig-4a
  *** Src[phosAb] phos(Y419)[phosAb] is increased itpo xCrk
    *** cells: HEK293T<xGab1> in BMS
    *** source: 19350053-Fig-S4
  *** Src[phosAb] phos(Y419)[phosAb] is increased itpo xCrk(mnr)"vCrk"
    *** cells: HEK293T<xGab1> in BMS
    *** source: 19350053-Fig-S4
  *** Src[phosAb] phos(Y419)[phosAb] is increased itpo xCrkI
    *** cells: HEK293T<xGab1> in BMS
    *** source: 19350053-Fig-S4
  *** Src[phosAb] phos(Y419)[phosAb] is increased itpo xCrkL
    *** cells: HEK293T<xGab1> in BMS
    *** source: 19350053-Fig-S4
  *** Src[phosAb] phos(Y419)[phosAb] is increased itpo xRhoa(Q63L)"CA"
    *** cells: HEK293T in BMLS
    *** inhibited by: xRhoa(Q63L/F39L) [substitution]
    *** inhibited by: xRhoa(Q63L/F39E) [substitution]
    *** unaffected by: xRhoa(Q63L/D45Q) [substitution]
    *** partially inhibited by: xRhoa(Q63L/V35D) [substitution]
    *** source: 11598209-Fig-9b
  *** Src[phosAb] phos(Y419)[phosAb] is increased itpo xRhoa(Q63L)"CA"
    *** cells: HEK293T in BMLS
    *** source: 11598209-Fig-5c
  *** Src[phosAb] phos(Y419)[phosAb] is increased itpo xShp2
    *** cells: mEFs<Shp2~null> in BMLS
    *** source: 14967142-Fig-1b
  *** Src[phosAb] phos(Y419)[phosAb] is unchanged itpo xGab1
    *** cells: HEK293T in BMS
    *** unaffected by: xGab1(del(241-411)) [substitution]
    *** source: 19350053-Fig-4a
  *** Src[phosAb] phos(Y530)[phosAb] is decreased itpo xDok2
    *** cells: COS1 in BMLS
    *** source: 15831486-Fig-4a
  *** Src[phosAb] phos(Y530)[phosAb] is decreased itpo xShp2
    *** cells: mEFs<Shp2~null> in BMLS
    *** source: 14967142-Fig-1b
  *** Src[phosAb] phos(Y530)[phosAb] is increased itao Shp2 [KO]
    *** cells: mEFs in BMLS
    *** source: 14967142-Fig-1a
  *** Src[phosAb] phos(Y530)[phosAb] is increased itao Shp2 [KO]
    *** cells: mEFs in BMLS
    *** source: 14967142-Fig-3b
  *** xSrc[tAb] copptby[WB] xTrip6[tAb] is detectable
    *** cells: HEK293T<xSrc><xTrip6> in BMLS
    *** inhibited by: xTrip6(Y55F) [substitution]
    *** source: 15988003-Fig-2d
  *** SRE-reporter[CAT] is increased itpo xMek1(mnr)"CA"
    *** cells: NIH3T3 in BMS
    *** inhibited by: xId2 [addition]
    *** source: 10022839-Fig-7c
  *** SRE-reporter[CAT] is increased itpo xMekk1
    *** cells: HELA in BMLS
    *** source: 8846788-Fig-3a
  *** SRE-reporter[Luc] is increased itpo xCdc42(Q61L)
    *** cells: CHO in BMLS
    *** bkg inhibited by: xDusp1 [addition]
    *** source: 9111305-Fig-8a
  *** SRE-reporter[Luc] is increased itpo xRac1(Q61L)
    *** cells: CHO in BMLS
    *** bkg inhibited by: xDusp1 [addition]
    *** source: 9111305-Fig-8a
  *** SRE-reporter[Luc] is increased itpo xRhoa(Q63L)
    *** cells: CHO in BMLS
    *** bkg inhibited by: xDusp1 [addition]
    *** source: 9111305-Fig-8a
  *** rSrf boundby[EMSA] rElk1{phos}[GST] is detectable
    *** cells: none
    *** comment: rSrf was already oligo-bound and was shifted by rElk1{phos}
    *** comment: rElk1 was phosed with rErk2{act}
    *** inhibited by: rElk1 [substitution]
    *** source: 9111305-Fig-2a
  *** rSrf boundby[EMSA] rElk1{phos}[GST] is detectable
    *** cells: none
    *** comment: rSrf was already oligo-bound and was shifted by rElk1{phos}
    *** comment: rElk1 was phosed with rP38a{act}
    *** inhibited by: rElk1 [substitution]
    *** source: 9111305-Fig-2a
  *** rSrf boundby[EMSA] rElk4{phos}[GST] is detectable
    *** cells: none
    *** comment: rSrf was already oligo-bound and was shifted by rElk4{phos}
    *** comment: rElk4 was phosed with rErk2{act}
    *** inhibited by: rElk4 [substitution]
    *** source: 9111305-Fig-2b
  *** rSrf boundby[EMSA] rElk4{phos}[GST] is detectable
    *** cells: none
    *** comment: rSrf was already oligo-bound and was shifted by rElk4{phos}
    *** comment: rElk4 was phosed with rP38a{act}
    *** inhibited by: rElk4 [substitution]
    *** source: 9111305-Fig-2b
*** Srf--
  *** Srf-gene mRNA[RTPCR] is decreased itao Pias2a [RNAi]
    *** cells: HELA in BMLS
    *** source: 15920481-Fig-1e
  *** rSrf(133-222) oligo-binding[EMSA] is detectable
    *** cells: none
    *** comment: rElk1 was present in the reaction
    *** source: 8622654-Fig-1a
  *** Srf[Ab] boundto(Egr1-gene)[ChIP] is detectable
    *** cells: mEFs in BMS
    *** comment: both the -400 and -100 Egr1-gene SRE clusters were detected
    *** source: 19417246-Fig-S5
  *** Srf[Ab] boundto(Egr1-gene)[ChIP] is detectable
    *** cells: mEFs<Med23~null> in BMS
    *** comment: both the -400 and -100 Egr1-gene SRE clusters were detected
    *** source: 19417246-Fig-4
  *** SrfRE-reporter[Luc] is increased itpo xGna12(Q229L)"CA"
    *** cells: HEK293T in BMS
    *** inhibited by: xArc3!CBDP [addition]
    *** unaffected by: xMlk3 [addition]
    *** source: 18851832-Fig-3c
  *** SrfRE-reporter[Luc] is increased itpo xGna13(Q229L)"CA"
    *** cells: HEK293T in BMS
    *** inhibited by: xArc3!CBDP [addition]
    *** unaffected by: xMlk3 [addition]
    *** source: 18851832-Fig-3c
  *** SrfRE-reporter[Luc] is increased itpo xGnaq(Q229L)"CA"
    *** cells: HEK293T in BMS
    *** inhibited by: xArc3!CBDP [addition]
    *** inhibited by: xMlk3 [addition]
    *** source: 18851832-Fig-3c
  *** SrfRE-reporter[Luc] is increased itpo xGnaq(Q229L)"CA"
    *** cells: HEK293T in BMS
    *** inhibited by: xMlk3 [addition]
    *** partially inhibited by: xMlk3(K144R)"KD" [addition]
    *** source: 18851832-Fig-3c
  *** xStam[Ab] copptby[WB] xJak2[Ab] is detectable
    *** cells: COS7 in BMS
    *** unaffected by: xStam(del(216-267))"DSH3" [substitution]
    *** inhibited by: xStam(del(355-388))"DIT" [substitution]
    *** inhibited by: xStam(1-370)"DY2" [substitution]
    *** source: 9133424-Fig-5d
  *** xStam[Ab] copptby[WB] xJak3[Ab] is undetectable
    *** cells: COS7 in BMS
    *** unaffected by: xStam(del(216-267))"DSH3" [substitution]
    *** unaffected by: xStam(del(355-388))"DIT" [substitution]
    *** unaffected by: xStam(1-370)"DY2" [substitution]
    *** source: 9133424-Fig-5c
  *** Stam[Ab]IP Yphos[pYAb] is increased itpo xJak1
    *** cells: COS7<xCsf2Ra><xCsf2Ra> in BMS
    *** source: 9133424-Fig-2b
  *** Stam[Ab]IP Yphos[pYAb] is increased itpo xJak1
    *** cells: COS7<xIL2Rb><xIL2Rg> in BMS
    *** source: 9133424-Fig-2a
  *** Stam[Ab]IP Yphos[pYAb] is increased itpo xJak2
    *** cells: COS7<xCsf2Ra><xCsf2Ra> in BMS
    *** source: 9133424-Fig-2b
  *** xStam[Ab]IP Yphos[pYAb] is increased itpo xJak2
    *** cells: COS7<xCsf2Ra><xCsf2Ra> in BMS "treated with Csf2 for 10 min"
    *** unaffected by: xStam(del(216-267))"DSH3" [substitution]
    *** inhibited by: xStam(del(355-388))"DIT" [substitution]
    *** inhibited by: xStam(1-370)"DY2" [substitution]
    *** source: 9133424-Fig-3c
  *** Stam[Ab]IP Yphos[pYAb] is increased itpo xJak3
    *** cells: COS7<xIL2Rb><xIL2Rg> in BMS
    *** source: 9133424-Fig-2a
  *** xStam[Ab]IP Yphos[pYAb] is increased itpo xJak3
    *** cells: COS7<xIL2Rb><xIL2Rg> in BMS "treated with IL2 for 10 min"
    *** unaffected by: xStam(del(216-267))"DSH3" [substitution]
    *** inhibited by: xStam(del(355-388))"DIT" [substitution]
    *** inhibited by: xStam(1-370)"DY2" [substitution]
    *** source: 9133424-Fig-3b
  *** Stam[Ab]IP Yphos[pYAb] is unchanged itpo xLck
    *** cells: COS7<xCsf2Ra><xCsf2Ra> in BMS
    *** source: 9133424-Fig-2b
  *** Stam[Ab]IP Yphos[pYAb] is unchanged itpo xLck
    *** cells: COS7<xIL2Rb><xIL2Rg> in BMS
    *** source: 9133424-Fig-2a
  *** Stam2[Ab] copptby[WB] Jak1[Ab] is undetectable
    *** cells: ILTMAT in BMS
    *** source: 10899310-Fig-2c
  *** Stam2[Ab] copptby[WB] Jak2[Ab] is undetectable
    *** cells: TF1 in BMS
    *** source: 10899310-Fig-2b
  *** Stam2[Ab] copptby[WB] Jak3[Ab] is undetectable
    *** cells: ILTMAT in BMS
    *** source: 10899310-Fig-2a
  *** Stam2[Ab] copptby[WB] Lck[Ab] is undetectable
    *** cells: ILTMAT in BMS
    *** source: 10899310-Fig-2e
  *** Stam2[Ab] copptby[WB] Tyk2[Ab] is undetectable
    *** cells: DAUDI in BMS
    *** source: 10899310-Fig-2d
  *** xStam2[tAb]IP Yphos[pYAb] is detectable
    *** cells: HEK293T<xEgfR> in BMLS "treated with Egf for 5 min"
    *** source: 10993906-Fig-3a
  *** xStam2[tAb]IP Yphos[pYAb] is detectable
    *** cells: HEK293T<xPdgfR?> in BMLS "treated with Pdgf for 5 min"
    *** source: 10993906-Fig-3a
  *** xStam2[tAb]IP Yphos[pYAb] is increased itpo xJak1
    *** cells: HEK293T in BMS
    *** source: 10993906-Fig-4
  *** xStam2[tAb]IP Yphos[pYAb] is increased itpo xJak2
    *** cells: HEK293T in BMS
    *** source: 10993906-Fig-4
  *** xStam2[tAb]IP Yphos[pYAb] is unchanged itpo xBmx
    *** cells: HEK293T in BMS
    *** source: 10993906-Fig-4
*** Stat1--
  *** rStat1(K410Q/K413Q)[Ab] boundby[WB] rRela[Ab] is detectable
    *** cells: none
    *** inhibited by: xStat1 [substitution]
    *** source: 16481475-Fig-S2
  *** xStat1(K410Q/K413Q)[Ab] copptby[WB] Rela[Ab] is detectable
    *** cells: U3A<Stat1~null><xStat1(K410Q/K413Q)> in BMS
    *** inhibited by: xStat1(K410R/K413R) [substitution]
    *** inhibited by: xStat1 [substitution]
    *** source: 16481475-Fig-7b
  *** pStat1[32P] phos[32P-ATP] is unchanged by xTec[Ab]IP
    *** cells: none
    *** IPfrom: SF9 in BMS
    *** comment: Stat1 from kinase reaction does not bind to a GAS oligo
    *** source: 7657660-Fig-5b
  *** rStat1[Ab] acetyl[KAcAb] is increased by xCbp[Ab]IP
    *** cells: none
    *** IPfrom: HEK293T<xCbp> in BMS
    *** source: 16481475-Fig-6b
  *** xStat1[Ab] copptby[WB] xParp14[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 16537510-Fig-2f
  *** Stat1[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: HUH7 in BMS "primed with Ifng for 24 hr"
    *** source: 11150296-Fig-1
  *** Stat1[Ab] methyl[RMeAb-ppt] is detectable
    *** cells: HELA in BMS
    *** unaffected by: N6-Methyl-2-deoxyadenosine [addition]
    *** unaffected by: Ifng (30 min) [stim]
    *** source: 15153491-Fig-6b
  *** Stat1[Ab] oligo-binding[EMSA] is detectable
    *** cells: hTh1 in BMS
    *** source: 9531298-Fig-3c
  *** Stat1[Ab] oligo-binding[EMSA] is detectable
    *** cells: KIT225 in BMS "treated with IL2 for 15 min"
    *** oligo: "FcgR-GAS" 5-GTATTTCCCAGAAAAGGAAC-3
    *** source: 7988557-Fig-7
  *** Stat1[Ab] oligo-binding[EMSA] is detectable
    *** cells: KIT225 in BMS "treated with IL2 for 15 min"
    *** oligo: "SIEM67" 5-GTCGACATTTCCCGTAAATC-3
    *** source: 7988557-Fig-7
  *** xStat1[Ab] oligo-binding[EMSA] is increased itpo xBmx
    *** cells: COS7 in BMS
    *** inhibited by: xPkcd [addition]
    *** source: 9373245-Fig-9a
  *** xStat1[Ab] oligo-binding[EMSA] is increased itpo xBmx
    *** cells: COS7 in BMS
    *** source: 9373245-Fig-1b
  *** Stat1[Ab] oligo-binding[EMSA] is increased itpo xBmx
    *** cells: COS7 in BMS
    *** source: 9373245-Fig-5
  *** xStat1[Ab] oligo-binding[EMSA] is increased itpo xBmx
    *** cells: COS7 in BMS
    *** unaffected by: xPkcb [addition]
    *** source: 9373245-Fig-9a
  *** xStat1[Ab] oligo-binding[EMSA] is increased itpo xBmx
    *** cells: COS7 in BMS
    *** unaffected by: xPkce [addition]
    *** source: 9373245-Fig-9a
  *** xStat1[Ab] oligo-binding[EMSA] is increased itpo xBmx
    *** cells: COS7 in BMS
    *** unaffected by: xPkcz [addition]
    *** source: 9373245-Fig-9a
  *** xStat1[Ab] oligo-binding[EMSA] is unchanged itpo xFyn
    *** cells: COS7 in BMS
    *** source: 9373245-Fig-1c
  *** xStat1[Ab] oligo-binding[EMSA] is unchanged itpo xSrc
    *** cells: COS7 in BMS
    *** source: 9373245-Fig-1c
  *** xStat1[Ab] oligo-binding[EMSA] is unchanged itpo xSyk
    *** cells: COS7 in BMS
    *** source: 9373245-Fig-1c
  *** xStat1[Ab] oligo-binding[EMSA] is unchanged itpo xTec
    *** cells: SF9 in BMS
    *** oligo: GAS 5-CTAGCAGTGTTTCCCCGAAACACGCTAG-3
    *** source: 7657660-Fig-3a
  *** Stat1[Ab] snaggedby[WB] rIL2Rb(240-525)[GST] is detectable
    *** cells: KIT225 in BMS "IL2-deprived"
    *** inhibited by: rIL2Rb(240-306)"prox" [substitution]
    *** unaffected by: rIL2Rb(306-382)"aci" [substitution]
    *** inhibited by: rIL2Rb(382-525)"cter" [substitution]
    *** source: 10602027-Fig-4
  *** Stat1[Ab] snaggedby[WB] rIL2Rb(306-382)"aci"[GST] is detectable
    *** cells: KIT225 in BMS "IL2-deprived"
    *** inhibited by: rIL2Rb(306-335)"aci1" [substitution]
    *** unaffected by: rIL2Rb(335-365)"aci2" [substitution]
    *** inhibited by: rIL2Rb(365-382)"aci3" [substitution]
    *** partially inhibited by: rIL2Rb((306-382)/Y338F/Y355F/Y358F/Y361F) [substitution]
    *** unaffected by: rIL2Rb((306-382)/Y338F) [substitution]
    *** unaffected by: rIL2Rb((306-382)/Y355F) [substitution]
    *** unaffected by: rIL2Rb((306-382)/Y358F) [substitution]
    *** unaffected by: rIL2Rb((306-382)/Y361F) [substitution]
    *** source: 10602027-Fig-7
  *** Stat1[Ab] Yphos[pYAb-ppt] is unchanged itpo xFer
    *** cells: COS1 in BMS
    *** source: 10878010-Fig-5c
  *** Stat1[Ab]IP acetyl[KAcAb] is decreased itpo xHdac3
    *** cells: HEK293T<xCbp> in BMS
    *** source: 19171783-Fig-4i
  *** Stat1[Ab]IP acetyl[KAcAb] is increased itpo xCbp
    *** cells: HEK293T in BMS
    *** does not req: Hdac3 [RNAi]
    *** source: 19171783-Fig-4j
  *** Stat1[Ab]IP acetyl[KAcAb] is increased itpo xCbp
    *** cells: HEK293T in BMS
    *** source: 16481475-Fig-6b
  *** xStat1[Ab]IP acetyl[KAcAb] is increased itpo xCbp
    *** cells: HEK293T<xStat1> in BMS
    *** inhibited by: xStat1(K410E/K413E) [substitution]
    *** source: 16481475-Fig-6e
  *** Stat1[Ab]IP sumo[tSuAb] is increased itpo xUbe2i
    *** cells: HEK293<xSumo1> in BMS "treated with Ifng for 30 min"
    *** inhibited by: xPias4 [addition]
    *** source: 16857984-Fig-1a
  *** Stat1[Ab]IP sumo[tSuAb] is unchanged itpo xPias4
    *** cells: HEK293<xSumo1> in BMS "treated with Ifng for 30 min"
    *** source: 16857984-Fig-1a
  *** xStat1[Ab]IP Yphos[pYAb] is increased itpo xBmx
    *** cells: SF9 in BMS
    *** source: 9373245-Fig-8a
  *** xStat1[Ab]IP Yphos[pYAb] is unchanged itpo xTec
    *** cells: SF9 in BMS
    *** source: 7657660-Fig-1a
  *** xStat1[MW] sumo[tSuAb] is increased itpo xMkk6(mnr)"CA"
    *** cells: COS7<xSumo1> in BMS
    *** source: 17897103-Fig-1
  *** Stat1[phosAb] phos(S727)[phosAb] is increased itao Socs1 [KO]
    *** cells: mKupfferCells in BMS
    *** source: 12433373-Fig-5b
  *** xStat1[phosAb] phos(S727)[phosAb] is increased itpo xMekk1(mnr)"CA"
    *** cells: COS1 in BMS
    *** source: 11278353-Fig-3b
  *** xStat1[phosAb] phos(S727)[phosAb] is increased itpo xMkk6(mnr)"CA"
    *** cells: COS7<xSumo1> in BMS
    *** inhibited by: SB202190 [addition]
    *** source: 17897103-Fig-2b
  *** xStat1[phosAb] phos(S727)[phosAb] is increased itpo xMkk6(mnr)"CA"
    *** cells: COS7<xSumo1> in BMS
    *** inhibited by: xP38?(mnr)"DN" [addition]
    *** source: 17897103-Fig-2a
  *** xStat1[phosAb] phos(S727)[phosAb] is increased itpo xMkk6(mnr)"CA"
    *** cells: COS7<xSumo1> in BMS
    *** partially inhibited by: SB202190 [addition]
    *** source: 17897103-Fig-3b
  *** xStat1[phosAb] phos(S727)[phosAb] is increased itpo xMkk6(mnr)"CA"
    *** cells: COS7<xSumo1> in BMS
    *** source: 17897103-Fig-1
  *** xStat1[phosAb] phos(S727)[phosAb] is increased itpo xMkk6(mnr)"CA"
    *** cells: COS7<xSumo1> in BMS
    *** source: 17897103-Fig-3a
  *** xStat1[phosAb] phos(S727)[phosAb] is increased itpo xMkk6(mnr)"CA"
    *** cells: COS7<xSumo1> in BMS
    *** unaffected by: xStat1(K703R) [substitution]
    *** unaffected by: xStat1(Y701F) [substitution]
    *** bkg inhibited by: xStat1(S727A) [substitution]
    *** source: 17897103-Fig-4a
  *** xStat1[phosAb] phos(S727)[phosAb] is increased itpo xRaf1(mnr)"CA"
    *** cells: COS7<xSumo1> in BMS
    *** inhibited by: PD98059 [addition]
    *** source: 17897103-Fig-3b
  *** xStat1[phosAb] phos(S727)[phosAb] is increased itpo xRaf1(mnr)"CA"
    *** cells: COS7<xSumo1> in BMS
    *** source: 17897103-Fig-3a
  *** xStat1[phosAb] phos(S727)[phosAb] is unchanged itpo xMek1(mnr)"CA"
    *** cells: COS7<xSumo1> in BMS
    *** source: 17897103-Fig-3a
  *** Stat1[phosAb] phos(Y701)[phosAb] is decreased itpo xSocs1
    *** cells: HEK293<xEgfR> in BMS
    *** source: 12070153-Fig-6b
  *** Stat1[phosAb] phos(Y701)[phosAb] is decreased itpo xSocs3
    *** cells: HEK293<xEgfR> in BMS
    *** source: 12070153-Fig-6b
  *** Stat1[phosAb] phos(Y701)[phosAb] is detectable
    *** cells: hCBLs<Cd4~pos> in BMS "treated with anti-Cd3/anti-Cd28 for 24 hr"
    *** unaffected by: anti-Ifng [cotreatment]
    *** unaffected by: IL12 [cotreatment]
    *** unaffected by: IL12 + anti-Ifng [cotreatment]
    *** unaffected by: anti-IL12 + Ifng [cotreatment]
    *** source: 16220539-Fig-2b
  *** Stat1[phosAb] phos(Y701)[phosAb] is detectable
    *** cells: hCBLs<Cd4~pos> in BMS "treated with anti-Cd3/anti-Cd28 for 48 hr"
    *** unaffected by: anti-Ifng [cotreatment]
    *** unaffected by: IL12 [cotreatment]
    *** unaffected by: IL12 + anti-Ifng [cotreatment]
    *** unaffected by: anti-IL12 + Ifng [cotreatment]
    *** source: 16220539-Fig-2b
  *** Stat1[phosAb] phos(Y701)[phosAb] is increased itao Socs1 [KO]
    *** cells: mKupfferCells in BMS
    *** source: 12433373-Fig-5b
  *** Stat1[phosAb] phos(Y701)[phosAb] is increased itpo xIkke
    *** cells: HEK293 in BMS
    *** reqs: Irf3 [RNAi]
    *** reqs: Ikk2 [RNAi]
    *** reqs: Jak1 [RNAi]
    *** reqs: Tyk2 [RNAi]
    *** reqs: Ifnb1 [RNAi]
    *** does not req: Irf7 [RNAi]
    *** does not req: Jak2 [RNAi]
    *** does not req: Tbk1 [RNAi]
    *** does not req: Stat3 [RNAi]
    *** source: 16199137-Fig-3a,6b,6c,6d
  *** xStat1[phosAb] phos(Y701)[phosAb] is increased itpo xTyk2
    *** cells: U3A<Stat1~null> in BMS
    *** inhibited by: xStat1(K410Q/K413Q) [substitution]
    *** source: 19171783-Fig-5b
  *** xStat1[phosAb] phos(Y701)[phosAb] is unchanged itpo xMekk1(CatDomain)"CA"
    *** cells: COS1 in BMS
    *** source: 11278353-Fig-3b
  *** pStat1[pYAb] Yphos[pYAb] is unchanged by xTec[Ab]IP
    *** cells: none
    *** IPfrom: SF9 in BMS
    *** source: 7657660-Fig-6b
  *** xStat1[tAb] copptby[WB] xRnf11[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 19131965-Fig-1a
  *** xStat1[tAb] locatedin(nucleus)[IHC] is detectable
    *** cells: HUH7<xStat1> in BMS
    *** source: 11150296-Fig-8a
  *** xStat1[tAb] oligo-binding[EMSA] is increased itpo xJak2
    *** cells: SF9<xStat1> in BMS
    *** inhibited by: xJak2(mnr)"KD" [substitution]
    *** source: 11150296-Fig-9b
  *** xStat1[tAb] oligo-binding[EMSA] is increased itpo xJak2
    *** cells: SF9<xStat1> in BMS
    *** inhibited by: xStat1(Y710A) [substitution]
    *** inhibited by: xStat1(K410A/K413A) [substitution]
    *** source: 11150296-Fig-9b
  *** xStat1[tAb] oligo-binding[EMSA] is increased itpo xJak2
    *** cells: SF9<xStat1><xStat2><xIrf9> in BMS
    *** inhibited by: xJak2(mnr)"KD" [substitution]
    *** source: 11150296-Fig-9c
  *** xStat1[tAb] oligo-binding[EMSA] is increased itpo xJak2
    *** cells: SF9<xStat1><xStat2><xIrf9> in BMS
    *** inhibited by: xStat1(Y710A) [substitution]
    *** inhibited by: xStat1(K410A/K413A) [substitution]
    *** source: 11150296-Fig-9c
  *** xStat1[tAb] oligomerization[2TagPpt] is detectable
    *** cells: U3A<Stat1~null><xStat1> in BMS "treated with Ifng + Vanadate for 60 min"
    *** enhanced by: xStat1(K410E/K413E) [substitution]
    *** inhibited by: xStat1(Y701F) [substitution]
    *** source: 11823427-Fig-1f
  *** xStat1[tAb] upshift[WBMS] is increased itpo xMkk6(mnr)"CA"
    *** cells: COS7<xSumo1> in BMS
    *** bkg inhibited by: xStat1(K703R) [substitution]
    *** unaffected by: xStat1(Y701F) [substitution]
    *** inhibited by: xStat1(S727A) [substitution]
    *** source: 17897103-Fig-4a
  *** xStat1[tAb] upshift[WBMS] is increased itpo xMkk6(mnr)"CA"
    *** cells: COS7<xSumo1> in BMS
    *** inhibited by: SB202190 [addition]
    *** source: 17897103-Fig-2b
  *** xStat1[tAb] upshift[WBMS] is increased itpo xMkk6(mnr)"CA"
    *** cells: COS7<xSumo1> in BMS
    *** inhibited by: xP38?(mnr)"DN" [addition]
    *** source: 17897103-Fig-2a
  *** xStat1[tAb] upshift[WBMS] is increased itpo xMkk6(mnr)"CA"
    *** cells: COS7<xSumo1> in BMS
    *** partially inhibited by: SB202190 [addition]
    *** source: 17897103-Fig-3b
  *** xStat1[tAb] upshift[WBMS] is increased itpo xMkk6(mnr)"CA"
    *** cells: COS7<xSumo1> in BMS
    *** source: 17897103-Fig-3a
  *** xStat1[tAb] upshift[WBMS] is increased itpo xRaf1(mnr)"CA"
    *** cells: COS7<xSumo1> in BMS
    *** partially inhibited by: PD98059 [addition]
    *** source: 17897103-Fig-3b
  *** xStat1[tAb] upshift[WBMS] is increased itpo xRaf1(mnr)"CA"
    *** cells: COS7<xSumo1> in BMS
    *** source: 17897103-Fig-3a
  *** xStat1[tAb] upshift[WBMS] is unchanged itpo xMek1(mnr)"CA"
    *** cells: COS7<xSumo1> in BMS
    *** source: 17897103-Fig-3a
  *** xStat1[tAb]IP acetyl[KAcAb] is increased itpo xCbp
    *** cells: HEK293T in BMS
    *** source: 17923090-Fig-S4b
  *** xStat1[tAb]IP acetyl[KAcAb] is unchanged itpo xEp300
    *** cells: HEK293T in BMS
    *** source: 17923090-Fig-S4b
  *** xStat1[tAb]IP acetyl[KAcAb] is unchanged itpo xKat2a
    *** cells: HEK293T in BMS
    *** source: 17923090-Fig-S4b
  *** xStat1[tAb]IP acetyl[KAcAb] is unchanged itpo xPcaf
    *** cells: HEK293T in BMS
    *** source: 17923090-Fig-S4b
  *** xStat1[tAb]IP Yphos[pYAb] is increased itpo xBmx
    *** cells: COS7 in BMS
    *** inhibited by: xPkcd [addition]
    *** source: 9373245-Fig-10
  *** xStat1[tAb]IP Yphos[pYAb] is increased itpo xBmx
    *** cells: COS7 in BMS
    *** source: 9373245-Fig-1a
  *** xStat1[tAb]IP Yphos[pYAb] is increased itpo xBmx
    *** cells: COS7 in BMS
    *** unaffected by: xPkcb [addition]
    *** source: 9373245-Fig-10
  *** rStat1{Yphos}[Ab] boundby[WB] rKpna1(404-538)[GST] is detectable
    *** cells: none
    *** comment: Stat1 was phosed in bacteria containing an activated Elk1 kinase
    *** inhibited by: rStat1 [substitution]
    *** source: 11927559-Fig-6a
  *** rStat1{Yphos}[Ab] boundby[WB] rKpna1(404-538)[GST] is detectable
    *** cells: none
    *** comment: Stat1 was phosed in bacteria containing an activated Elk1 kinase
    *** inhibited by: rStat1(R602L) [substitution]
    *** source: 11927559-Fig-6b
*** Stat2--
  *** xStat2(1-314)[tAb] copptby[WB] xIrf9[Ab] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xStat2(315-485) [substitution]
    *** source: 17923090-Fig-S3a
  *** xStat2(315-485)[tAb] copptby[WB] xStat1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xStat2(1-314) [substitution]
    *** source: 17923090-Fig-6e
  *** xStat2(K390R)[tAb] copptby[WB] xStat1[tAb] is detectable
    *** cells: U6A<Stat2~null><xIrf9> in BMS
    *** inhibited by: Ifna (30 min) [stim]
    *** source: 17923090-Fig-6i
  *** Stat2[Ab] copptby[WB] Stat1[Ab] is detectable
    *** cells: HELA in BMS
    *** unaffected by: Ifna (tnr) [stim]
    *** source: 17923090-Fig-6h
  *** Stat2[Ab] copptby[WB] xStat1[tAb] is detectable
    *** cells: U3A<Stat1~null> in BMS
    *** unaffected by: xStat1(K410Q/K413Q) [substitution]
    *** source: 19171783-Fig-3k
  *** Stat2[Ab] copptby[WB] xStat1[tAb] is detectable
    *** cells: U3A<Stat1~null> in BMS
    *** unaffected by: xStat1(K410R/K413R) [substitution]
    *** unaffected by: xStat1(K410Q/K413Q) [substitution]
    *** source: 19171783-Fig-3j
  *** Stat2[Ab] locatedin(nucleus)[IHC] is undetectable
    *** cells: HUH7 in BMS
    *** unaffected by: xStat1 [addition]
    *** source: 11150296-Fig-8a
  *** Stat2[Ab] locatedin(nucleus)[IHC] is undetectable
    *** cells: HUH7 in BMS "primed with Ifng for 24 hr"
    *** source: 11150296-Fig-1
  *** Stat2[Ab] oligo-binding[EMSA] is detectable
    *** cells: KIT225 in BMS "treated with IL2 for 15 min"
    *** oligo: "FcgR-GAS" 5-GTATTTCCCAGAAAAGGAAC-3
    *** source: 7988557-Fig-7
  *** Stat2[Ab] oligo-binding[EMSA] is undetectable
    *** cells: KIT225 in BMS "treated with IL2 for 15 min"
    *** oligo: "SIEM67" 5-GTCGACATTTCCCGTAAATC-3
    *** source: 7988557-Fig-7
  *** Stat2[Ab] Yphos[pYAb-ppt] is unchanged itpo xFer
    *** cells: COS1 in BMS
    *** source: 10878010-Fig-5c
  *** Stat2[phosAb] phos(Y690)[phosAb] is unchanged itpo xIkke
    *** cells: HEK293 in BMS
    *** source: 16199137-Fig-3a
  *** xStat2[tAb] copptby[WB] xIfnaR2[Ab] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xStat2(K182R) [substitution]
    *** unaffected by: xStat2(K184R) [substitution]
    *** unaffected by: xStat2(K194R) [substitution]
    *** unaffected by: xStat2(K197R) [substitution]
    *** source: 17923090-Fig-S3c
  *** xStat2[tAb] copptby[WB] xIrf9[Ab] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xStat2(K182R) [substitution]
    *** unaffected by: xStat2(K184R) [substitution]
    *** unaffected by: xStat2(K194R) [substitution]
    *** unaffected by: xStat2(K197R) [substitution]
    *** source: 17923090-Fig-S3b
  *** xStat2[tAb] copptby[WB] xIrf9[tAb] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xStat2(K384R) [substitution]
    *** unaffected by: xStat2(K390R) [substitution]
    *** unaffected by: xStat2(K415R) [substitution]
    *** unaffected by: xStat2(K419R) [substitution]
    *** unaffected by: xStat2(K592R) [substitution]
    *** unaffected by: xStat2(K384R/K415R/K419R) [substitution]
    *** source: 17923090-Fig-6f
  *** xStat2[tAb] copptby[WB] xStat1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** enhanced by: xStat1(E393A/E394A) [substitution]
    *** source: 17923090-Fig-6g
  *** xStat2[tAb] copptby[WB] xStat1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** enhanced by: xStat2(K390R) [substitution]
    *** unaffected by: xStat2(K390E) [substitution]
    *** source: 17923090-Fig-6g
  *** xStat2[tAb] copptby[WB] xStat1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xStat2(K384R) [substitution]
    *** enhanced by: xStat2(K390R) [substitution]
    *** enhanced by: xStat2(K415R) [substitution]
    *** unaffected by: xStat2(K419R) [substitution]
    *** unaffected by: xStat2(K592R) [substitution]
    *** unaffected by: xStat2(K384R/K415R/K419R) [substitution]
    *** source: 17923090-Fig-6f
  *** xStat2[tAb] copptby[WB] xStat1[tAb] is detectable
    *** cells: U6A<Stat2~null><xIrf9> in BMS
    *** enhanced by: xStat2(K390R) [substitution]
    *** source: 17923090-Fig-6i
  *** xStat2[tAb] copptby[WB] xStat1[tAb] is detectable
    *** cells: U6A<Stat2~null><xIrf9> in BMS
    *** unaffected by: Ifna (30 min) [stim]
    *** source: 17923090-Fig-6i
  *** xStat2[tAb] oligo-binding[EMSA] is increased itpo xJak2
    *** cells: SF9<xStat1><xStat2><xIrf9> in BMS
    *** inhibited by: xJak2(mnr)"KD" [substitution]
    *** source: 11150296-Fig-9c
  *** xStat2[tAb] oligo-binding[EMSA] is increased itpo xJak2
    *** cells: SF9<xStat1><xStat2><xIrf9> in BMS
    *** inhibited by: xStat1(Y710A) [substitution]
    *** inhibited by: xStat1(K410A/K413A) [substitution]
    *** source: 11150296-Fig-9c
  *** xStat2[tAb]IP acetyl[KAcAb] is increased itpo xCbp
    *** cells: HEK293T in BMS
    *** source: 17923090-Fig-6b
  *** xStat2[tAb]IP acetyl[KAcAb] is increased itpo xEp300
    *** cells: HEK293T in BMS
    *** source: 17923090-Fig-6b
  *** xStat2[tAb]IP acetyl[KAcAb] is unchanged itpo xKat2a
    *** cells: HEK293T in BMS
    *** source: 17923090-Fig-6b
  *** xStat2[tAb]IP acetyl[KAcAb] is unchanged itpo xPcaf
    *** cells: HEK293T in BMS
    *** source: 17923090-Fig-6b
*** Stat3--
  *** Stat3-reporter[Luc] is decreased itpo xPias3
    *** cells: NIH3T3 in BMS "treated with IL6/IL6Rsol for 15 min"
    *** reversed by: xMitf [addition]
    *** reversed by: xMitf(S409A) [addition]
    *** source: 15572665-Fig-3b
  *** Stat3-reporter[Luc] is detectable
    *** cells: HEPG2 in BMS
    *** inhibited by: xSocs1 [addition]
    *** source: 9202126-Fig-4b
  *** Stat3-reporter[Luc] is increased itpo xFoxo1
    *** cells: HEPG2 in BMS
    *** source: 12456685-Fig-4d
  *** Stat3-reporter[Luc] is increased itpo xRac1(G12V)
    *** cells: HEPG2 in BMS
    *** inhibited by: Rottlerin [pretreatment]
    *** source: 11335711-Fig-5b
  *** Stat3-reporter[Luc] is increased itpo xRac1(G12V)
    *** cells: HEPG2 in BMS
    *** source: 10727406-Fig-4c
  *** xStat3(600-720)[tAb] copptby[WB] xPkcd[GST] is detectable
    *** cells: COS1 in BMS
    *** unaffected by: xPkcd(Y52F) [substitution]
    *** unaffected by: xPkcd(Y155F) [substitution]
    *** unaffected by: xPkcd(Y187F) [substitution]
    *** source: 12361954-Fig-2c
  *** xStat3(600-720)[tAb] copptby[WB] xPkcd[GST] is detectable
    *** cells: COS1 in BMS
    *** unaffected by: xStat3((600-720)/R609L) [substitution]
    *** source: 12361954-Fig-2b
  *** rStat3(702-714)[Ab] upshift[WBMS] is unchanged by (rSumo1 + rSae1 + rUba2 + rUbe2i)
    *** cells: none
    *** source: 16857984-Fig-2b
  *** xStat3(C661A/C663N)[tAb] copptby[WB] xPias3[tAb] is detectable
    *** cells: NIH3T3 in BMS
    *** inhibited by: xStat3(Y705F) [substitution]
    *** source: 15572665-Fig-4a
  *** xStat3(C661A/C663N)[tAb] locatedin(nucleus)[IHC] is detectable
    *** cells: NIH3T3<xPias3><xMitf> in BMS
    *** inhibited by: xStat3(Y705F) [substitution]
    *** source: 15572665-Fig-5c
  *** xStat3(Y705F/R609A)[Ab] snaggedby[WB] rKpna1(mnr)"del-IBB"[GST] is undetectable
    *** cells: COS1<xStat3(Y705F/R609A)> in BMLS
    *** source: 15919823-Fig-5a
  *** xStat3(Y705F/R609A)[Ab] snaggedby[WB] rKpna2(mnr)"del-IBB"[GST] is undetectable
    *** cells: COS1<xStat3(Y705F/R609A)> in BMLS
    *** source: 15919823-Fig-5a
  *** xStat3(Y705F/R609A)[Ab] snaggedby[WB] rKpna4(mnr)"del-IBB"[GST] is detectable
    *** cells: COS1<xStat3(Y705F/R609A)> in BMLS
    *** source: 15919823-Fig-5a
  *** xStat3(Y705F/R609A)[Ab] snaggedby[WB] rKpna4(mnr)"del-IBB"[GST] is detectable
    *** cells: COS1<xStat3(Y705F/R609A)> in BMLS
    *** unaffected by: rKpna4(19-521) [substitution]
    *** unaffected by: rKpna4(19-315) [substitution]
    *** inhibited by: rKpna4(309-521) [substitution]
    *** source: 15919823-Fig-5c
  *** xStat3(Y705F/R609A)[Ab] snaggedby[WB] rKpna4(mnr)"del-IBB"[GST] is detectable
    *** cells: COS1<xStat3(Y705F/R609A)> in BMLS
    *** unaffected by: xStat3(150-770) [substitution]
    *** inhibited by: xStat3(162-770) [substitution]
    *** source: 15919823-Fig-5b
  *** xStat3(Y705F/R609A)[Ab] snaggedby[WB] rKpna4(mnr)"del-IBB"[GST] is detectable
    *** cells: COS1<xStat3(Y705F/R609A)> in BMLS
    *** unaffected by: xStat3(150-770) [substitution]
    *** inhibited by: xStat3(162-770) [substitution]
    *** unaffected by: xStat3(150-163) [substitution]
    *** source: 15919823-Fig-10
  *** xStat3(Y705F/R609A)[Ab] snaggedby[WB] rKpna5(mnr)"del-IBB"[GST] is detectable
    *** cells: COS1<xStat3(Y705F/R609A)> in BMLS
    *** source: 15919823-Fig-5a
  *** xStat3(Y705F/R609A)[Ab] snaggedby[WB] rKpna6(mnr)"del-IBB"[GST] is undetectable
    *** cells: COS1<xStat3(Y705F/R609A)> in BMLS
    *** source: 15919823-Fig-5a
  *** xStat3(Y705F/R609A)[XFP] locatedin(nucleus)[IHC] is decreased itao Kpna4 [RNAi]
    *** cells: HELA<xStat3(Y705F/R609A)> in BMLS
    *** source: 15919823-Fig-6c
  *** xStat3(Y705F/R609A)[XFP] locatedin(nucleus)[IHC] is unchanged itao Kpna1 [RNAi]
    *** cells: HELA<xStat3(Y705F/R609A)> in BMLS
    *** source: 15919823-Fig-6c
  *** xStat3(Y705F/R609A)[XFP] locatedin(nucleus)[IHC] is unchanged itao Kpna2 [RNAi]
    *** cells: HELA<xStat3(Y705F/R609A)> in BMLS
    *** source: 15919823-Fig-6c
  *** xStat3(Y705F/R609A)[XFP] oligomerization[2TagPpt] is detectable
    *** cells: COS1<xStat3(Y705F/R609A)> in BMS
    *** unaffected by: xStat3(150-770) [substitution]
    *** unaffected by: xStat3(162-770) [substitution]
    *** source: 15919823-Fig-9a
  *** rStat3[32P] phos[32P-ATP] is increased by rIrak1
    *** cells: none
    *** inhibited by: rStat3(S727A) [substitution]
    *** comment: controls without Irak1 were not performed
    *** source: 15465816-Fig-3b
  *** Stat3[Ab] copptby[WB] EgfR[Ab] is detectable
    *** cells: HACAT in BMLS "nuclear-extracts"
    *** source: 15950906-Fig-S1d
  *** Stat3[Ab] copptby[WB] Foxo1[Ab] is detectable
    *** cells: HEPG2 in BMLS "pretreated with LY294002, followed by IL6 for 10 min"
    *** source: 12456685-Fig-6a
  *** Stat3[Ab] copptby[WB] Src[Ab] is increased itpo xRala(Q72L)"CA"
    *** cells: HEK293 in BMLS
    *** source: 10675331-Fig-4a
  *** Stat3[Ab] copptby[WB] xEgfR[Ab] is detectable
    *** cells: CHO<xEgfR> in BMLS
    *** source: 15950906-Fig-5e
  *** Stat3[Ab] copptby[WB] xHes5[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 15156153-Fig-2d
  *** xStat3[Ab] copptby[WB] xStat2[Ab] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xStat2(K384R) [substitution]
    *** unaffected by: xStat2(K390R) [substitution]
    *** unaffected by: xStat2(K415R) [substitution]
    *** unaffected by: xStat2(K419R) [substitution]
    *** unaffected by: xStat2(K592R) [substitution]
    *** unaffected by: xStat2(K384R/K415R/K419R) [substitution]
    *** source: 17923090-Fig-S3e
  *** Stat3[Ab] infraction(nuclear)[WB] is detectable-but unchanged itpo xEgfR
    *** cells: CHO in BMLS
    *** unaffected by: xEgfR(R645A/R646A/R647A) [substitution]
    *** source: 15950906-Fig-5d
  *** Stat3[Ab] oligo-binding[EMSA] is detectable
    *** cells: hTh2 in BMS
    *** source: 9531298-Fig-3c
  *** xStat3[Ab] oligo-binding[EMSA] is increased itpo xBmx
    *** cells: COS7 in BMS
    *** source: 9373245-Fig-2a
  *** xStat3[Ab] oligo-binding[EMSA] is unchanged itpo xSyk
    *** cells: COS7 in BMS
    *** source: 9373245-Fig-2a
  *** Stat3[Ab] snaggedby[WB] rIL2Rb(240-525)[GST] is detectable
    *** cells: KIT225 in BMS "IL2-deprived"
    *** inhibited by: rIL2Rb(240-306)"prox" [substitution]
    *** unaffected by: rIL2Rb(306-382)"aci" [substitution]
    *** inhibited by: rIL2Rb(382-525)"cter" [substitution]
    *** source: 10602027-Fig-4
  *** Stat3[Ab] snaggedby[WB] rIL2Rb(306-382)"aci"[GST] is detectable
    *** cells: KIT225 in BMS "IL2-deprived"
    *** inhibited by: rIL2Rb(306-335)"aci1" [substitution]
    *** unaffected by: rIL2Rb(335-365)"aci2" [substitution]
    *** inhibited by: rIL2Rb(365-382)"aci3" [substitution]
    *** partially inhibited by: rIL2Rb((306-382)/Y338F/Y355F/Y358F/Y361F) [substitution]
    *** unaffected by: rIL2Rb((306-382)/Y338F) [substitution]
    *** unaffected by: rIL2Rb((306-382)/Y355F) [substitution]
    *** unaffected by: rIL2Rb((306-382)/Y358F) [substitution]
    *** unaffected by: rIL2Rb((306-382)/Y361F) [substitution]
    *** source: 10602027-Fig-7
  *** Stat3[Ab]IP phos(S727)[phosAb] is unchanged by rErk1{act}
    *** cells: none
    *** IPfrom: JB6CL41 in BMLS
    *** source: 11553624-Fig-5a
  *** Stat3[Ab]IP phos(S727)[phosAb] is unchanged by rErk2{act}
    *** cells: none
    *** IPfrom: JB6CL41 in BMLS
    *** source: 11553624-Fig-5a
  *** Stat3[Ab]IP phos(S727)[phosAb] is unchanged by rP38a{act}
    *** cells: none
    *** IPfrom: JB6CL41 in BMLS
    *** source: 11553624-Fig-5a
  *** Stat3[Ab]IP Sphos[pSAb] is detectable
    *** cells: HELA in BMS
    *** source: 11278353-Fig-1b
  *** Stat3[Ab]IP Sphos[pSAb] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 11278353-Fig-1c
  *** xStat3[Ab]IP Yphos[pYAb] is detectable
    *** cells: COS7<xJak3> in BMS
    *** inhibited by: xJak3(K855A)"KD" [substitution]
    *** source: 10825200-Fig-1a
  *** xStat3[Ab]IP Yphos[pYAb] is detectable
    *** cells: COS7<xLck> in BMS
    *** inhibited by: xLck(mnr)"KD" [substitution]
    *** unaffected by: xLck(mnr)"CA" [substitution]
    *** source: 10825200-Fig-1a
  *** xStat3[Ab]IP Yphos[pYAb] is increased itpo xBmx
    *** cells: SF9 in BMS
    *** source: 9373245-Fig-7a
  *** xStat3[Ab]IP Yphos[pYAb] is increased itpo xSyk
    *** cells: COS7 in BMS
    *** inhibited by: xSyk(mnr)"KD" [substitution]
    *** source: 10825200-Fig-4a
  *** Stat3[Ab]IP Yphos[pYAb] is undetectable
    *** cells: HELA in BMS
    *** source: 11278353-Fig-1b
  *** Stat3[Ab]IP Yphos[pYAb] is undetectable
    *** cells: NIH3T3 in BMS
    *** source: 11278353-Fig-1c
  *** xStat3[phosAb] phos(S705)[phosAb] is increased itao Grb2 [RNAi]
    *** cells: A431 in BMS "treated with Egf (30 min)"
    *** source: 14498832-Fig-2
  *** xStat3[phosAb] phos(S727)[phosAb] is detectable
    *** cells: COS1 in BMS
    *** source: 11278353-Fig-1a
  *** xStat3[phosAb] phos(S727)[phosAb] is detectable
    *** cells: COS1<xStat3> in BMS
    *** partially inhibited by: SB203580 [pretreatment]
    *** partially inhibited by: PD98059 [pretreatment]
    *** source: 10521505-Fig-4
  *** Stat3[phosAb] phos(S727)[phosAb] is detectable
    *** cells: HEPG2 in BMS
    *** inhibited by: xMkk4(mnr)"DN" [addition]
    *** inhibited by: xVav?(mnr)"DN" [addition]
    *** inhibited by: xRac1(T17N) [addition]
    *** inhibited by: xMekk?(mnr)"DN" [addition]
    *** source: 10727406-Fig-3c
  *** Stat3[phosAb] phos(S727)[phosAb] is increased itpo xRac1(G12V)
    *** cells: HEPG2 in BMS
    *** source: 11335711-Fig-5a
  *** Stat3[phosAb] phos(S727)[phosAb] is increased itpo xRhoa(Q63L)"CA"
    *** cells: HEK293T in BMLS
    *** source: 11598209-Fig-6
  *** Stat3[phosAb] phos(Y705)[phosAb] is detectable
    *** cells: HEPG2 in BMLS "plated on collagen"
    *** unaffected by: Gefitinib [cotreatment]
    *** unaffected by: PD325901 [cotreatment]
    *** unaffected by: BMS345541 [cotreatment]
    *** unaffected by: PHA818637 [cotreatment]
    *** unaffected by: ZSTK474 [cotreatment]
    *** source: 19953085-Fig-S1
  *** Stat3[phosAb] phos(Y705)[phosAb] is detectable
    *** cells: MYLA2059 in BMS
    *** unaffected by: xShp2 [addition]
    *** unaffected by: Shp2(C459S)"CIA" [addition]
    *** source: 12543077-Fig-4
  *** Stat3[phosAb] phos(Y705)[phosAb] is increased itpo xHes5
    *** cells: COS1 in BMS
    *** source: 15156153-Fig-2b
  *** xStat3[phosAb] phos(Y705)[phosAb] is increased itpo xHes5
    *** cells: COS1 in BMS
    *** source: 15156153-Fig-2b
  *** Stat3[phosAb] phos(Y705)[phosAb] is increased itpo xIkke
    *** cells: HEK293 in BMS
    *** source: 16199137-Fig-3a
  *** xStat3[phosAb] phos(Y705)[phosAb] is increased itpo xJak1
    *** cells: COS1 in BMS
    *** source: 15156153-Fig-2d
  *** Stat3[phosAb] phos(Y705)[phosAb] is increased itpo xRhoa(Q63L)"CA"
    *** cells: HEK293T in BMS
    *** source: 11598209-Fig-3a
  *** Stat3[phosAb] phos(Y705)[phosAb] is unchanged itpo xRac1(G12V)
    *** cells: HEPG2 in BMS
    *** source: 11335711-Fig-5a
  *** xStat3[phosAb] phos(Y705)[phosAb] is undetectable
    *** cells: COS1 in BMS
    *** source: 11278353-Fig-1a
  *** xStat3[pYAb]IP Yphos[pYAb] is increased itpo xJak2
    *** cells: HEK293T in BMS
    *** inhibited by: xSocs1 [addition]
    *** source: 9202126-Fig-3d
  *** Stat3[RE] oligo-binding[EMSA] is decreased itpo xAmph
    *** cells: NIH3T3<xEgfR> in BMS
    *** source: 12093727-Fig-2a
  *** Stat3[RE] oligo-binding[EMSA] is decreased itpo xEpn2
    *** cells: NIH3T3<xEgfR> in BMS
    *** source: 12093727-Fig-2a
  *** xStat3[tAb] copptby[WB] EgfR[Ab] is detectable
    *** cells: COS1 in BMS
    *** inhibited by: xGrb2 [addition]
    *** source: 14498832-Fig-6
  *** xStat3[tAb] copptby[WB] Gp130[Ab] is increased itpo xPkcd
    *** cells: HEPG2 in BMS "treated with IL6 for 15 min"
    *** source: 12361954-Fig-6c
  *** xStat3[tAb] copptby[WB] xPkcd[GST] is detectable
    *** cells: COS1 in BMS
    *** inhibited by: xPkcd(1-219)"F1" [substitution]
    *** inhibited by: xPkcd(220-380)"F2" [substitution]
    *** unaffected by: xPkcd(381-735)"F3" [substitution]
    *** unaffected by: xPkcd(381-481)"C4" [substitution]
    *** unaffected by: xPkcd(481-735)"V4" [substitution]
    *** source: 12361954-Fig-3b
  *** xStat3[tAb] copptby[WB] xPkcd[GST] is detectable
    *** cells: COS1 in BMS
    *** partially inhibited by: xStat3(R609L) [substitution]
    *** source: 12361954-Fig-2a
  *** xStat3[tAb] copptby[WB] xPkcd[GST] is detectable
    *** cells: COS1 in BMS
    *** unaffected by: xStat3(138-770)"delN" [substitution]
    *** unaffected by: xStat3(320-770)"delN4H" [substitution]
    *** unaffected by: xStat3(395-770)"delN4D1" [substitution]
    *** unaffected by: xStat3(500-770)"LKCT" [substitution]
    *** unaffected by: xStat3(600-770)"SH2CT" [substitution]
    *** inhibited by: xStat3(1-328)"ND4H" [substitution]
    *** inhibited by: xStat3(320-600)"DBLK" [substitution]
    *** unaffected by: xStat3(320-700)"DBSH2" [substitution]
    *** inhibited by: xStat3(670-770)"CT" [substitution]
    *** unaffected by: xStat3(600-740)"SH2740" [substitution]
    *** unaffected by: xStat3(600-720)"SH2720" [substitution]
    *** unaffected by: xStat3(600-715)"SH2715" [substitution]
    *** inhibited by: xStat3(600-715)"SH2688" [substitution]
    *** source: 12361954-Fig-1a
  *** xStat3[tAb] locatedin(nucleus)[IHC] is detectable
    *** cells: HELA<xStat3> in BMLS
    *** source: 15919823-Fig-1c
  *** xStat3[tAb]IP phos(Y705)[phosAb] is increased itpo xRala(Q72L)"CA"
    *** cells: PC12 in BMS
    *** source: 10675331-Fig-1
  *** xStat3[tAb]IP phos(Y705)[phosAb] is increased itpo xRgl4
    *** cells: PC12 in BMS
    *** source: 10675331-Fig-1
  *** xStat3[XFP] locatedin(nucleus)[IHC] is detectable
    *** cells: HELA<xStat3> in BMLS
    *** inhibited by: xStat3(del(150-163)) [substitution]
    *** source: 15919823-Fig-4d
  *** xStat3[XFP] locatedin(nucleus)[IHC] is detectable
    *** cells: HELA<xStat3> in BMLS
    *** source: 15919823-Fig-1c
  *** xStat3[XFP] locatedin(nucleus)[IHC] is detectable
    *** cells: HELA<xStat3> in BMLS
    *** unaffected by: xStat3(1-322) [substitution]
    *** unaffected by: xStat3(1-495) [substitution]
    *** inhibited by: xStat3(323-770) [substitution]
    *** unaffected by: xStat3(135-770) [substitution]
    *** unaffected by: xStat3(150-770) [substitution]
    *** inhibited by: xStat3(162-770) [substitution]
    *** inhibited by: xStat3(180-770) [substitution]
    *** source: 15919823-Fig-4b
  *** xStat3[XFP] locatedin(nucleus)[IHC] is detectable
    *** cells: HELA<xStat3> in BMLS
    *** unaffected by: xStat3(V77A/L78A/F174W) [substitution]
    *** source: 15919823-Fig-9b
  *** xStat3[XFP] locatedin(nucleus)[IHC] is detectable
    *** cells: HELA<xStat3> in BMLS
    *** unaffected by: xStat3(Y705F/R609A) [substitution]
    *** source: 15919823-Fig-2b
  *** Stat3{phos}[phosAb] copptby[WB] Pparg[Ab] is detectable
    *** cells: KAS61 in BMS "IL6 deprived for 24 hr, treated with IL6 for 10 min"
    *** unaffected by: 15dPGJ2 [pretreatment]
    *** inhibited by: Troglitazone [pretreatment]
    *** source: 14975242-Fig-6a
  *** Stat4-gene mRNA[RTPCR] is detectable
    *** cells: mSpCD4TCs in BMS "pretreated with anti-Cd3 + anti-Cd28 + IL12 for 5 days"
    *** does not req: Stat6 [KO]
    *** does not req: Tbet [KO]
    *** source: 19324016-Fig-3a
  *** Stat4[Ab] copptby[WB] Jun[Ab] is detectable
    *** cells: 2D6 in BMS "stimulated with IL12 for tnr" "nuclear-extracts"
    *** source: 11801649-Fig-6b
  *** Stat4[Ab] copptby[WB] Jun[Ab] is detectable
    *** cells: 2D6 in BMS "stimulated with IL12/IL18 for tnr" "nuclear-extracts"
    *** source: 11801649-Fig-6a
  *** Stat4[Ab] copptby[WB] Jun[Ab] is detectable
    *** cells: 2D6 in BMS "stimulated with IL12/IL18 for tnr" "nuclear-extracts"
    *** source: 11801649-Fig-6b
  *** Stat4[Ab] copptby[WB] Jun[Ab] is undetectable
    *** cells: 2D6 in BMS "stimulated with IL18 for tnr" "nuclear-extracts"
    *** source: 11801649-Fig-6b
  *** Stat4[Ab] oligo-binding[EMSA] is detectable
    *** cells: hTh1 in BMS "restimulated with anti-Cd3, IL2, IL12 for 1 hr"
    *** source: 9531298-Fig-4b
  *** Stat4[Ab] oligo-binding[EMSA] is detectable
    *** cells: hTh2 in BMS "restimulated with anti-Cd3, IL2, IL12 for 1 hr"
    *** source: 9531298-Fig-4b
  *** Stat4[Ab] oligo-binding[EMSA] is undetectable
    *** cells: hTh1 in BMS "restimulated with anti-Cd3, IL2, IL4 for 1 hr"
    *** source: 9531298-Fig-4b
  *** Stat4[Ab] oligo-binding[EMSA] is undetectable
    *** cells: hTh2 in BMS "restimulated with anti-Cd3, IL2, IL4 for 1 hr"
    *** source: 9531298-Fig-4b
  *** Stat4[Ab] prot-exp[WB] is decreased itpo xHlx
    *** cells: NK92 in BMS "treated with IL12/IL18 for 24 hr"
    *** source: 17110450-Fig-5b
  *** Stat4[Ab] prot-exp[WB] is unchanged itpo xHlx
    *** cells: NK92 in BMS
    *** source: 17110450-Fig-5b
  *** xStat4[Ab]IP phos(S271)[phosAb] is increased itpo xGadd45b
    *** cells: HEK293T in BMS
    *** partially inhibited by: xMkk6(mnr)"DN" [addition]
    *** source: 12213961-Fig-1b
  *** xStat4[Ab]IP phos(S271)[phosAb] is increased itpo xGadd45b
    *** cells: HEK293T in BMS
    *** source: 12213961-Fig-1a
  *** xStat4[Ab]IP phos(S271)[phosAb] is increased itpo xGadd45g
    *** cells: HEK293T in BMS
    *** partially inhibited by: xMkk6(mnr)"DN" [addition]
    *** source: 12213961-Fig-1b
  *** xStat4[Ab]IP phos(S271)[phosAb] is increased itpo xGadd45g
    *** cells: HEK293T in BMS
    *** source: 12213961-Fig-1a
  *** xStat4[Ab]IP phos(S271)[phosAb] is increased itpo xMkk6
    *** cells: HEK293T in BMS
    *** inhibited by: xMkk6(mnr)"DN" [addition]
    *** source: 12213961-Fig-1b
  *** xStat4[Ab]IP phos(S271)[phosAb] is increased itpo xMkk6
    *** cells: HEK293T in BMS
    *** source: 12213961-Fig-1a
  *** xStat4[Ab]IP phos(S271)[phosAb] is increased itpo xRac1(mnr)"CA"
    *** cells: HEK293T in BMS
    *** inhibited by: xMkk6(mnr)"DN" [addition]
    *** source: 12213961-Fig-1b
  *** xStat4[Ab]IP phos(S721)[phosAb] is increased itpo xMkk6
    *** cells: HEK293T<xStat4> in BMS
    *** inhibited by: xStat4(S727A) [substitution]
    *** source: 10961885-Fig-6c
  *** xStat4[Ab]IP phos(S721)[phosAb] is increased itpo xMkk6
    *** cells: HEK293T<xStat4> in BMS
    *** unaffected by: xP38a [addition]
    *** source: 10961885-Fig-6c
  *** Stat4[Ab]IP Yphos[pYAb] is detectable
    *** cells: mLNTCs in BMS "treated with anti-Cd3 for 24 hr"
    *** unaffected by: anti-Cd28 [cotreatment]
    *** source: 14734615-Fig-4c
  *** Stat4[phosAb] phos(sitenr)[phosAb] is detectable
    *** cells: mSpCD4TCs in BMS "pretreated with anti-Cd3 + anti-Cd28 + IL12 for 5 days and restim with IL12 for 20 min"
    *** does not req: Stat6 [KO]
    *** partially reqs: Tbet [KO]
    *** source: 19324016-Fig-3b
*** Stat5--
  *** Stat5-reporter[Luc] is detectable
    *** cells: L929 in BMS
    *** inhibited by: xSocs1 [addition]
    *** source: 9202126-Fig-4a
  *** xStat5?[Ab] oligo-binding[EMSA] is increased itpo xBmx
    *** cells: COS7 in BMS
    *** source: 9373245-Fig-3b
  *** xStat5?[tAb]IP Yphos[pYAb] is unchanged itpo xGrb2
    *** cells: COS1 in BMS "treated with Egf (30 min)"
    *** source: 14498832-Fig-8
  *** rStat5a(637-794) phos[32P-ATP] is increased by Jak1[Ab]IP
    *** cells: none
    *** IPfrom: COS7 in BMS
    *** inhibited by: rStat5a((637-792)/Y694F) [substitution]
    *** source: 9382798-Fig-1
  *** Stat5a[Ab] snaggedby[WB] rIL2Rb(240-525){phos}[GST] is detectable
    *** cells: KIT225 in BMS "IL2-deprived"
    *** inhibited by: rIL2Rb(240-525) [substitution]
    *** source: 10602027-Fig-6
  *** Stat5a[Ab] snaggedby[WB] rIL2Rb(382-525){phos}[GST] is detectable
    *** cells: KIT225 in BMS "IL2-deprived"
    *** inhibited by: rIL2Rb(382-525) [substitution]
    *** source: 10602027-Fig-6
  *** Stat5a[Ab]IP Yphos[pYAb] is decreased itpo xIkba(mnr)"del-Nterm"
    *** cells: mThyCs in BMS "treated with PMA + Ionomycin for 16 hr"
    *** source: 11160275-Fig-7c
  *** xStat5a[Ab]IP Yphos[pYAb] is detectable
    *** cells: COS7<xLck> in BMS
    *** inhibited by: xLck(mnr)"KD" [substitution]
    *** unaffected by: xLck(mnr)"CA" [substitution]
    *** source: 10825200-Fig-1b
  *** xStat5a[Ab]IP Yphos[pYAb] is increased itpo xSyk
    *** cells: COS7 in BMS
    *** inhibited by: xSyk(mnr)"KD" [substitution]
    *** source: 10825200-Fig-4a
  *** xStat5a[tAb] copptby[WB] EgfR[Ab] is detectable
    *** cells: A431 in BMLS
    *** unaffected by: Egf (5,15,30,60,120 min) [stim]
    *** source: 10358079-Fig-3c
  *** xStat5a[tAb]IP Yphos[pYAb] is detectable
    *** cells: NIH3T3<xEgfR> in BMLS
    *** inhibited by: xStat5a(Y694F) [substitution]
    *** inhibited by: xStat5a(R618L) [substitution]
    *** source: 10358079-Fig-4a
  *** xStat5a[tAb]IP Yphos[pYAb] is detectable
    *** cells: NIH3T3<xEgfR> in BMLS
    *** partially inhibited by: xJak1(mnr)"DN" [addition]
    *** partially inhibited by: xJak2(mnr)"DN" [addition]
    *** source: 10358079-Fig-10
  *** xStat5a[tAb]IP Yphos[pYAb] is detectable
    *** cells: NIH3T3<xEgfR><xPrlR> in BMLS
    *** inhibited by: xStat5a(Y694F) [substitution]
    *** inhibited by: xStat5a(R618L) [substitution]
    *** source: 10358079-Fig-4b
  *** xStat5a[tAb]IP Yphos[pYAb] is detectable
    *** cells: NIH3T3<xEgfR><xPrlR> in BMLS
    *** unaffected by: xJak1(mnr)"DN" [addition]
    *** inhibited by: xJak2(mnr)"DN" [addition]
    *** source: 10358079-Fig-10
  *** Stat5b[Ab] snaggedby[WB] rIL2Rb(240-525)[GST] is undetectable
    *** cells: KIT225 in BMS "IL2-deprived"
    *** unaffected by: rIL2Rb(240-306)"prox" [substitution]
    *** unaffected by: rIL2Rb(306-382)"aci" [substitution]
    *** unaffected by: rIL2Rb(382-525)"cter" [substitution]
    *** source: 10602027-Fig-5
  *** Stat5b[Ab] snaggedby[WB] rIL2Rb(240-525){phos}[GST] is detectable
    *** cells: KIT225 in BMS "IL2-deprived"
    *** inhibited by: rIL2Rb(240-525) [substitution]
    *** source: 10602027-Fig-6a
  *** Stat5b[Ab] snaggedby[WB] rIL2Rb(382-525){phos}[GST] is detectable
    *** cells: KIT225 in BMS "IL2-deprived"
    *** inhibited by: rIL2Rb((382-525)/Y392F/Y510F) [substitution]
    *** inhibited by: rIL2Rb((382-525)/Y510F) [substitution]
    *** unaffected by: rIL2Rb((382-525)/Y392F) [substitution]
    *** source: 10602027-Fig-6b
  *** Stat5b[Ab] snaggedby[WB] rIL2Rb(382-525){phos}[GST] is detectable
    *** cells: KIT225 in BMS "IL2-deprived"
    *** inhibited by: rIL2Rb(382-525) [substitution]
    *** source: 10602027-Fig-6a
  *** Stat5s[Ab] copptby[WB] Stat3[Ab] is undetectable
    *** cells: KIT225 in BMS "IL2-deprived"
    *** unaffected by: Ifna (10 min) [stim]
    *** source: 9305919-Fig-2
  *** Stat5s[Ab] copptby[WB] Stat3[Ab] is undetectable
    *** cells: KIT225 in BMS "IL2-deprived"
    *** unaffected by: IL2 (10 min) [stim]
    *** source: 9305919-Fig-2
  *** Stat5s[Ab] oligo-binding[EMSA] is decreased itpo xIkba(mnr)"del-Nterm"
    *** cells: mTCs in BMS "treated with anti-Cd3 + anti-Cd28 for 16 hr"
    *** source: 11160275-Fig-7b
  *** Stat5s[Ab] oligo-binding[EMSA] is decreased itpo xIkba(mnr)"del-Nterm"
    *** cells: mThyCs in BMS "treated with PMA + Ionomycin + Cd28 for 20 hr"
    *** source: 11160275-Fig-7a
  *** Stat5s[Ab] oligo-binding[EMSA] is detectable
    *** cells: CTLL2 in BMS "IL2-deprived" "nuclear-extracts" "Treated with IL2 for 20 min"
    *** oligo: "PRE" 5-AGATTTCTAGGAATTCAATCC-3
    *** source: 7781605-Fig-2a
  *** Stat5s[Ab] oligo-binding[EMSA] is detectable
    *** cells: TF1 in BMS "Growth-Factor-deprived" "nuclear-extracts" "Treated with Epo for 20 min"
    *** oligo: "PRE" 5-AGATTTCTAGGAATTCAATCC-3
    *** source: 7781605-Fig-3a
  *** Stat5s[Ab] oligo-binding[EMSA] is undetectable
    *** cells: CTLL2 in BMS "IL2-deprived" "nuclear-extracts" "Treated with IL4 for 20 min"
    *** oligo: "PRE" 5-AGATTTCTAGGAATTCAATCC-3
    *** source: 7781605-Fig-2b
  *** xStat5s[Ab]IP phos(DGYV)[phosAb] is decreased by PP1
    *** cells: HEK293T<xTrka><xStat5a><xStat5b> in BMS
    *** inhibited by: PP1 [addition]
    *** source: 15702476-Fig-4a
  *** xStat5s[Ab]IP phos(DGYV)[phosAb] is detectable
    *** cells: GAMMA2A<Jak2~null><xTrka><xStat5a><xStat5b> in BMS "treated with Ngf for 24 hr"
    *** source: 15702476-Fig-3a
  *** xStat5s[Ab]IP phos(DGYV)[phosAb] is detectable
    *** cells: HEK293T<xTrka><xStat5a><xStat5b> in BMS "treated with Ngf for 24 hr"
    *** inhibited by: xTrka(K538A)"KD" [substitution]
    *** unaffected by: xTrka(del(491-497))"del-Shc-binding" [substitution]
    *** unaffected by: xTrka(Y785F)"del-Plcg1-binding" [substitution]
    *** source: 15702476-Fig-2a
  *** xStat5s[Ab]IP phos(DGYV)[phosAb] is detectable
    *** cells: HEK293T<xTrka><xStat5a><xStat5b> in BMS "treated with Ngf for 24 hr"
    *** unaffected by: U73122 [addition]
    *** source: 15702476-Fig-2c
  *** xStat5s[Ab]IP Yphos[pYAb] is detectable
    *** cells: HEK293T<xTrka><xStat5a><xStat5b> in BMS "treated with Ngf for 24 hr"
    *** source: 15702476-Fig-2a
  *** Stat5s[phosAb] phos(sitenr)[phosAb] is increased itpo xLck    
    *** cells: HEK293T<xGab2> in BMS
    *** enhanced by: xLck(mnr)"CA" [substitution]
    *** inhibited by: xLck(mnr)"KD" [substitution]
    *** source: 10849428-Fig-6b
  *** Stat5s[phosAb] phos(sitenr)[phosAb] is unchanged itpo xSyk
    *** cells: HEK293T<xGab2> in BMS
    *** source: 10849428-Fig-6b
  *** Stat5s[phosAb] phos(Y694)[phosAb] is increased itpo xIkke
    *** cells: HEK293 in BMS
    *** source: 16199137-Fig-3a
  *** xStat6[Ab] copptby[WB] Ikk1[Ab] is undetectable
    *** cells: HEK293T<xStat6> in BMS
    *** source: 10648614-Fig-7a
  *** xStat6[Ab] copptby[WB] xParp14[tAb] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: IL4 (tnr) [stim]
    *** source: 16537510-Fig-1b
  *** xStat6[Ab] copptby[WB] xParp14[tAb] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xParp14(mnr)"macroH2A-domains" [substitution]
    *** unaffected by: xParp14(mnr)"macroH2A-domains/Cterm" [substitution]
    *** source: 16537510-Fig-S7
  *** Stat6[Ab] methyl[RMeAb-ppt] is detectable
    *** cells: HELA in BMS
    *** unaffected by: N6-Methyl-2-deoxyadenosine [addition]
    *** unaffected by: IL4 (15 min) [stim]
    *** source: 15153491-Fig-6a
  *** Stat6[Ab] oligo-binding[EMSA] is detectable
    *** cells: hTh2 in BMS
    *** source: 9531298-Fig-3c
  *** Stat6[Ab] snaggedby[WB] rIL2Rb(240-525)[GST] is undetectable
    *** cells: KIT225 in BMS "IL2-deprived"
    *** unaffected by: rIL2Rb(240-306)"prox" [substitution]
    *** unaffected by: rIL2Rb(306-382)"aci" [substitution]
    *** unaffected by: rIL2Rb(382-525)"cter" [substitution]
    *** source: 10602027-Fig-5
  *** xStat6[tAb] methyl[RMeAb-ppt] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: N6-Methyl-2-deoxyadenosine [addition]
    *** source: 15153491-Fig-4
  *** xStat6[tAb] methyl[RMeAb-ppt] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xStat6(R27A) [substitution]
    *** source: 15153491-Fig-1b
  *** Stat6RE-reporter[Luc] is increased itpo xParp14
    *** cells: HEPG2 in BMS
    *** partially inhibited by: xParp14(1216-1817) [substitution]
    *** source: 16537510-Fig-3a
  *** Stat6RE-reporter[Luc] is increased itpo xParp14
    *** cells: HEPG2<xStat6> in BMS
    *** inhibited by: xStat6(mnr)"del-Cterm" [substitution]
    *** source: 16537510-Fig-2a
  *** Stat6RE-reporter[Luc] is increased itpo xParp14
    *** cells: HEPG2<xStat6> in BMS
    *** partially inhibited by: xParp14(1216-1817) [substitution]
    *** source: 16537510-Fig-3a
  *** Stat6RE-reporter[Luc] is increased itpo xParp14
    *** cells: HEPG2<xStat6> in BMS
    *** partially inhibited by: xParp14(mnr)"macroH2A-domains" [substitution]
    *** source: 16537510-Fig-5a
  *** Stat6RE-reporter[Luc] is increased itpo xParp14
    *** cells: HEPG2<xStat6> in BMS
    *** source: 16537510-Fig-2b
  *** Stat6RE-reporter[Luc] is increased itpo xParp14
    *** cells: HEPG2<xStat6> in BMS
    *** source: 16537510-Fig-2d
  *** Stat6RE-reporter[Luc] is increased itpo xParp14
    *** cells: JURKAT<Pten~null><xStat6> in BMS
    *** bkg inhibited by: xStat6(mnr)"del-Cterm" [substitution]
    *** source: 16537510-Fig-2c
  *** StatRE-reporter[Luc] is increased itpo Stat3(mnr)"CA"
    *** cells: HEK293 in BMS
    *** source: 16645171-Fig-2b
  *** StatRE-reporter[Luc] is increased itpo Stat5a(mnr)"CA"
    *** cells: HEK293 in BMS
    *** source: 16645171-Fig-2b
  *** StatRE-reporter[Luc] is increased itpo xLck
    *** cells: NIH3T3<xIL2Ra><xIL2Rb><xIL2Rg><Jak3~null><Lck~null> in BMS
    *** enhanced by: xLck(mnr)"CA" [substitution]
    *** source: 10825200-Fig-1b
  *** StatRE-reporter[Luc] is increased itpo xSyk
    *** cells: NIH3T3<xIL2Ra><xIL2Rb><xIL2Rg><Jak3~null><Lck~null> in BMS
    *** source: 10825200-Fig-4b
*** Stau2--
  *** Stau2[Ab] colocwith[IHC] Stau1[Ab] is detectable
    *** cells: SHSY5Y in BMS "differentiated with retinoic acid for 7 days"
    *** source: 15121898(D)
  *** Stau2[Ab] copptby[WB] xStau1[tAb] is detectable
    *** cells: HEK293T in BMS "infected with vaccinia vTf7-3 virus"
    *** source: 15121898(D)
  *** Stau2[MS] copptby[WB] xStau1[tAb] is detectable
    *** cells: HEK293T in BMS "infected with vaccinia vTf7-3 virus"
    *** source: 15121898(D)
  *** xStk4(1-326)[tAb] copptby[WB] xRheb[GST] is undetectable
    *** cells: HEK293T<xRheb><xStk4(1-326)> in BMS
    *** source: 15854902-Fig-4a
*** Stk11--
  *** xStk11ip[tAb] copptby[WB] xLkb1[tAb] is detectable
    *** cells: COS in BMS
    *** unaffected by: xSmad4 [omission]
    *** source: 11741830-Fig-5b
  *** xStk11ip[tAb] locatedin(cytoplasm)[IHC] is detectable
    *** cells: HELA in BMS
    *** comment: pattern is perinuclear in large spots
    *** source: 11741830-Fig-3a
*** Stk39--
  *** xStk39[tAb] copptby[WB] xWnk1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 16263722(D)
  *** xStk39[tAb] copptby[WB] xWnk4[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 16263722(D)
  *** Strada[Ab] copptby[WB] xAkt1[GST] is undetectable
    *** cells: HEK293T in BMS
    *** source: 12805220-Fig-2a
  *** Strada[Ab] copptby[WB] xDapp1[GST] is undetectable
    *** cells: HEK293T in BMS
    *** source: 12805220-Fig-2a
  *** Strada[Ab] copptby[WB] xMsk1[GST] is undetectable
    *** cells: HEK293T in BMS
    *** source: 12805220-Fig-2a
  *** Strada[Ab] copptby[WB] xPdpk1[GST] is undetectable
    *** cells: HEK293T in BMS
    *** source: 12805220-Fig-2a
  *** Strada[Ab] copptby[WB] xPlekha1[GST] is undetectable
    *** cells: HEK293T in BMS
    *** source: 12805220-Fig-2a
  *** Strada[Ab] copptby[WB] xS6k1[GST] is undetectable
    *** cells: HEK293T in BMS
    *** source: 12805220-Fig-2a
  *** xStrada[tAb] copptby[WB] xLkb1[GST] is detectable
    *** cells: HEK293 in BMS
    *** enhanced by: xCab39L [addition]
    *** source: 14517248-Fig-8b
  *** xStrada[tAb] copptby[WB] xLkb1[tAb] is detectable
    *** cells: HEK293<xAmpka1><xCab39> in BMS
    *** unaffected by: xLkb1(S325A/S428A) [substitution]
    *** source: 19187764-Fig-5c
  *** xStradb[tAb] copptby[WB] xLkb1[GST] is increased itpo xCab39
    *** cells: HEK293 in BMS
    *** source: 14517248-Fig-S5
  *** xStradb[tAb] prot-exp[WB] is increased itpo xCab39
    *** cells: HEK293 in BMS
    *** source: 14517248-Fig-S5
  *** xStradb[tAb] prot-exp[WB] is increased itpo xCab39L
    *** cells: HEK293 in BMS
    *** source: 14517248-Fig-S5
  *** xStrap[tAb] copptby[WB] xSmad1[tAb] is undetectable
    *** cells: COS1 in BMS
    *** source: 10757800(D)
  *** xStrap[tAb] copptby[WB] xSmad2[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 10757800(D)
  *** xStrap[tAb] copptby[WB] xSmad3[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 10757800(D)
  *** xStrap[tAb] copptby[WB] xSmad6[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 10757800(D)
  *** xStrap[tAb] copptby[WB] xSmad7[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 10757800(D)
  *** xStrap[tAb] copptby[WB] xTgfbR2[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 10757800(D)
  *** xStrap[tAb] oligomerization[2TagPpt] is detectable
    *** cells: COS1 in BMS
    *** source: 10757800(D)
  *** xStrap[tAb]IP phos[32Pi] is increased itpo xTgfbR1
    *** cells: COS1 in BMS
    *** inhibited by: xTgfbR1(K232R)"KD" [substitution]
    *** source: 10757800(D)
  *** xStrap[tAb]IP phos[32Pi] is increased itpo xTgfbR2
    *** cells: COS1 in BMS
    *** inhibited by: xTgfbR2(K277R)"KD" [substitution]
    *** source: 10757800(D)
  *** xStxbp1[Ab] copptby[WB] xPld2[Ab] is detectable
    *** cells: COS7<xStxbp1><xPld2> in BMLS
    *** source: 14744865-Fig-8a
  *** xStxbp1[Ab] locatedin(cellmembrane)[IHC] is increased itpo xPld2
    *** cells: COS7<xStxbp1> in BMLS
    *** source: 14744865-Fig-8c
  *** xStxbp1[Ab] locatedin(cytoplasm)[IHC] is detectable
    *** cells: COS7<xStxbp1> in BMLS
    *** source: 14744865-Fig-8b
  *** Sumo1[Ab] copptby[WB] xStat1[tAb] is detectable
    *** cells: U3A<Stat1~null> in BMS
    *** unaffected by: xStat1(K410Q/K413Q) [substitution]
    *** source: 19171783-Fig-S3b
  *** Sumo1[tAb] boundto(Egr1-gene)[ChIP] is detectable
    *** cells: HELA in BMS
    *** inhibited by: PMA [addition]
    *** source: 14992729-Fig-4e
  *** Sumo1[tAb] boundto(Egr1-gene)[ChIP] is detectable
    *** cells: HELA in BMS
    *** inhibited by: xUbe2i(mnr)"DN" [addition]
    *** source: 14992729-Fig-4e
  *** Supt3h[Ab] copptby[WB] Max[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 12660246-Fig-1a
  *** Supt3h[Ab] copptby[WB] xKat2a[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12660246-Fig-1a
  *** Supt3h[Ab] copptby[WB] xMyc[tAb] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xMyc(111-439) [substitution]
    *** source: 12660246-Fig-1b
  *** Supt3h[Ab] snaggedby[WB] rMyc[GST] is detectable
    *** cells: HELA in BMS "nuclear-extracts"
    *** source: 12660246-Fig-2a
  *** xSyk(mnr)"KD"[Ab]IP Yphos[pYAb] is increased itpo xJak1
    *** cells: COS7 in BMS
    *** inhibited by: xJak1(mnr)"KD" [substitution]
    *** source: 10825200-Fig-6a
  *** xSyk(mnr)"KD"[Ab]IP Yphos[pYAb] is unchanged itpo xJak3
    *** cells: COS7 in BMS
    *** unaffected by: xJak3(mnr)"KD" [substitution]
    *** source: 10825200-Fig-6a
  *** Syk[Ab] copptby[WB] Stam[Ab] is undetectable
    *** cells: ILTMAT in BMS
    *** source: 9133424-Fig-4
  *** xSyk[Ab] copptby[WB] xFak2[Ab] is undetectable
    *** cells: COS in BMS
    *** source: 9512511-Fig-3c
  *** xSyk[Ab]IP Yphos[pYAb] is detectable
    *** cells: COS7 in BMS
    *** source: 10825200-Fig-6a
  *** Syk[Ab]IP Yphos[pYAb] is increased itpo xDap12
    *** cells: mBMPOs<Dap12~null> in BMS "Csf1-and-Rankl-deprived"
    *** source: 18691974-Fig-2e
*** Tab1--
  *** xTab1(437-504)"Cterm"[tAb] copptby[WB] xTak1[tAb] is detectable
    *** cells: HELA in BMS
    *** source: 10838074-Fig-4a
  *** xTab1(437-504)"Cterm"[tAb] phos[WBMS] is increased itpo xTak1
    *** cells: HELA in BMS
    *** source: 10838074-Fig-3
  *** Tab1[Ab] phos[WBMS] is detectable
    *** cells: HEK293I1A<Irak1~null><xIrak1> in BMS
    *** reqs: xIrak1 [omission]
    *** unaffected by: xIrak1(K293A)"KD" [substitution]
    *** source: 11518704-Fig-6b
  *** xTab1[Ab] upshift[WBMS] is detectable
    *** cells: Ecoli<xTak1> in BugMedium
    *** inhibited by: xTak1(K63W) [substitution]
    *** unaffected by: xTak1(T178A) [substitution]
    *** unaffected by: xTak1(T178E) [substitution]
    *** unaffected by: xTak1(T184A) [substitution]
    *** unaffected by: xTak1(T184E) [substitution]
    *** unaffected by: xTak1(T187A) [substitution]
    *** unaffected by: xTak1(T187E) [substitution]
    *** inhibited by: xTak1(S192A) [substitution]
    *** inhibited by: xTak1(S192E) [substitution]
    *** source: 20538596-Fig-6
  *** rTab1[Ab] upshift[WBMS] is detectable
    *** cells: none
    *** comment: reaction also contains rTak1
    *** inhibited by: rTak1(K63W) [substitution]
    *** source: 20538596-Fig-2d
  *** rTab1[Ab] upshift[WBMS] is detectable
    *** cells: none
    *** comment: reaction also contains rTak1
    *** inhibited by: rTak1(K63W) [substitution]
    *** unaffected by: rTak1(A236E/M240E)"AM" [substitution]
    *** enhanced by: rTak1(F237E/W241E)"FW" [substitution]
    *** unaffected by: rTak1(W241E/V243E)"WV" [substitution]
    *** unaffected by: rTak1(I239E/V243E)"IV" [substitution]
    *** source: 20538596-Fig-5e
  *** rTab1[Ab] upshift[WBMS] is detectable
    *** cells: none
    *** comment: reaction also contains rTak1
    *** inhibited by: rTak1(K63W) [substitution]
    *** unaffected by: rTak1(A236K/M240K)"AM" [substitution]
    *** enhanced by: rTak1(F237K/W241K)"FW" [substitution]
    *** enhanced by: rTak1(W241K/V243K)"WV" [substitution]
    *** unaffected by: rTak1(I239K/V243K)"IV" [substitution]
    *** source: 20538596-Fig-5e
  *** rTab1[Ab] upshift[WBMS] is detectable
    *** cells: none
    *** comment: reaction also contains rTak1
    *** unaffected by: 5Z7Oxozeaenol [addition]
    *** source: 20538596-Fig-2d
  *** xTab1[Ab] upshift[WBMS] is increased itpo xTak1
    *** cells: Ecoli in BugMedium
    *** enhanced by: xTab2 [addition]
    *** source: 20538596-Fig-1a
  *** Tab1[phosAb] phos(S438)[phosAb] is detectable
    *** cells: mEFs in BMLS
    *** inhibited by: PD184352 [addition]
    *** source: 18021073-Fig-9a
  *** Tab1[phosAb] phos(S438)[phosAb] is detectable
    *** cells: mEFs in BMLS
    *** reqs: Jnk1 and/or Jnk2 [DKO]
    *** source: 18021073-Fig-9a
  *** xTab1[tAb] copptby[WB] xTak1[Ab] is detectable
    *** cells: mMesangialCells<xTak1><xTab1> in BMS
    *** unaffected by: xTgfbR1 [addition]
    *** source: 19556242-Fig-6a
  *** xTab1[tAb] copptby[WB] xTak1[Ab] is detectable
    *** cells: mMesangialCells<xTak1><xTab1> in BMS
    *** unaffected by: xTgfbR2 [addition]
    *** source: 19556242-Fig-6a
  *** xTab1[tAb] copptby[WB] xTak1[tAb] is detectable
    *** cells: HELA in BMS
    *** inhibited by: xTab1(1-436)"Nterm" [substitution]
    *** unaffected by: xTab1(437-504)"Cterm" [substitution]
    *** source: 10838074-Fig-3
  *** xTab1[tAb] copptby[WB] xTak1[tAb] is detectable
    *** cells: HELA in BMS
    *** unaffected by: xTak1(23-606) [substitution]
    *** unaffected by: xTak1(T184E/T187E) [substitution]
    *** unaffected by: xTak1(K63W) [substitution]
    *** source: 10838074-Fig-1
  *** xTab1[tAb] copptby[WB] xTak1[tAb] is detectable
    *** cells: HELA<xTak1><xTab1> in BMS
    *** inhibited by: xTab1(1-436)"Nterm" [substitution]
    *** unaffected by: xTab1(437-504)"Cterm" [substitution]
    *** unaffected by: xTab1(481-504)"C3" [substitution]
    *** source: 15590691-Fig-8b
  *** xTab1[tAb] phos[WBMS] is increased itpo xTak1
    *** cells: HEK293T in BMS
    *** unaffected by: xTak1(K172D) [substitution]
    *** unaffected by: xTak1(K209D) [substitution]
    *** inhibited by: xTak1(K63D) [substitution]
    *** source: 19843958-Fig-S6
  *** xTab1[tAb] phos[WBMS] is increased itpo xTak1
    *** cells: HELA in BMS
    *** unaffected by: xTak1(23-606) [substitution]
    *** unaffected by: xTak1(T184E/T187E) [substitution]
    *** inhibited by: xTak1(K63W) [substitution]
    *** source: 10838074-Fig-1
  *** xTab1[tAb] phos[WBMS] is increased itpo xTak1
    *** cells: mEFs in BMS
    *** does not req: Mekk3 [KO]
    *** source: 19843958-Fig-S5a
*** Tab2--
  *** Tab2[Ab] copptby[WB] Tak1[Ab] is detectable
    *** cells: mMesangialCells in BMS
    *** source: 19556242-Fig-8a
  *** Tab2[Ab] copptby[WB] TgfbR1[Ab] is detectable
    *** cells: mMesangialCells in BMS
    *** source: 19556242-Fig-8a
  *** Tab2[Ab] copptby[WB] xNlk[tAb] is detectable
    *** cells: HEK293T<xNlk> in BMS
    *** source: 20194509-Fig-1e
  *** Tab2[Ab] phos[WBMS] is detectable
    *** cells: HEK293I1A<Irak1~null><xIrak1> in BMS
    *** reqs: xIrak1 [omission]
    *** source: 11518704-Fig-6b
  *** xTab2[Ab] upshift[WBMS] is increased itpo xTraf6
    *** cells: HEK293 in BMS
    *** source: 15327770(D)
  *** Tab2[Ab]IP IVKA(Ikk2)[32P-ATP] is detectable
    *** cells: HEK293 in BMS "treated with Camptothecin for 2 hr"
    *** partially inhibited by: KU55933 [cotreatment]
    *** source: 20932476-Fig-2d
  *** Tab2[Ab]IP IVKA(Ikk2)[32P-ATP] is detectable
    *** cells: HEK293 in BMS "treated with IR for 2 hr"
    *** partially inhibited by: KU55933 [cotreatment]
    *** source: 20932476-Fig-2d
  *** Tab2[Ab]IP IVKA(Mkk6)[32P-ATP] is increased itpo xTraf6
    *** cells: HEK293 in BMS
    *** inhibited by: xTraf6(C70A)"E3-mut" [substitution]
    *** inhibited by: xTraf6(K142R) [substitution]
    *** source: 17135271-Fig-4b
  *** Tab2[Ab]IP phos[WBMS] is detectable
    *** cells: mEFs in BMLS "immortalized"
    *** reqs: P38a [KO]
    *** source: 14670075-Fig-5b
  *** Tab2[Ab]IP phos[WBMS] is detectable
    *** cells: mEFs in BMLS "immortalized"
    *** reqs: P38a [KO]
    *** source: 14670075-Fig-5c
  *** xTab2[Ab]IP upshift[WBMS] is increased itpo xTraf6
    *** cells: HEK293 in BMS
    *** source: 15327770(D)
  *** xTab2[tAb] copptby[WB] xJnk?[tAb] is undetectable
    *** cells: HEK293T<xJnk?><xTab2> in BMS
    *** source: 20194509-Fig-1c
  *** xTab2[tAb] copptby[WB] xNlk[tAb] is detectable
    *** cells: HEK293T<xNlk><xTab2> in BMS
    *** source: 20194509-Fig-1c
  *** xTab2[tAb] copptby[WB] xNlk[tAb] is detectable
    *** cells: HEK293T<xNlk><xTab2><xTak1(K63W)> in BMS
    *** source: 20194509-Fig-2a
  *** xTab2[tAb] copptby[WB] xP38?[tAb] is undetectable
    *** cells: HEK293T<xP38?><xTab2> in BMS
    *** source: 20194509-Fig-1c
  *** xTab2[tAb]IP IVKA(auto)[32P-ATP] is increased itpo xTpl2
    *** cells: HEK293 in BMS
    *** inhibited by: xTpl2(K167M) [substitution]
    *** source: 15670770-Fig-3c
  *** xTab2[tAb]IP IVKA(Ikk?,Ikba)[32P-ATP] is increased by (rTraf6 + Ube1 + rUbc13 + rUev1a + rUbiq)
    *** cells: none
    *** IPfrom: HEK293 in BMS
    *** reqs: rTraf6 [omission]
    *** source: 15327770(D)
  *** xTab2[tAb]IP IVKA(Mkk6)[32P-ATP] is increased by (rTraf6 + Ube1 + rUbc13 + rUev1a + rUbiq)
    *** cells: none
    *** IPfrom: HEK293 in BMS
    *** reqs: rTraf6 [omission]
    *** source: 15327770(D)
  *** xTab2[tAb]IP ubiq[UbAb] is increased itpo xTraf6
    *** cells: HEK293<xIL1R1> in BMS
    *** source: 14633987-Fig-6a
  *** xTab2[tAb]IP ubiq[UbAb] is unchanged itpo xTraf2
    *** cells: HEK293<xIL1R1> in BMS
    *** source: 14633987-Fig-6a
*** Tab3--
  *** xTab3[tAb]IP IVKA(Ikk?,Ikba)[32P-ATP] is increased by (rTraf6 + Ube1 + rUbc13 + rUev1a + rUbiq)
    *** cells: none
    *** IPfrom: HEK293 in BMS
    *** reqs: rTraf6 [omission]
    *** source: 15327770(D)
  *** xTab3[tAb]IP ubiq[UbAb] is increased itpo xTraf6
    *** cells: HEK293<xIL1R1> in BMS
    *** inhibited by: xTab3(del(478-661)) [substitution]
    *** source: 14633987-Fig-6a
  *** xTab3[tAb]IP ubiq[UbAb] is unchanged itpo xTraf2
    *** cells: HEK293<xIL1R1> in BMS
    *** source: 14633987-Fig-6a
  *** Tada2a[Ab] snaggedby[WB] rMyc[GST] is detectable
    *** cells: HELA in BMS "nuclear-extracts"
    *** source: 12660246-Fig-2a
  *** Taf1[Ab] snaggedby[WB] rMyc[GST] is undetectable
    *** cells: HELA in BMS "nuclear-extracts"
    *** source: 12660246-Fig-2a
  *** Taf4[Ab] snaggedby[WB] rMyc[GST] is undetectable
    *** cells: HELA in BMS "nuclear-extracts"
    *** source: 12660246-Fig-2a
  *** Taf5[Ab] snaggedby[WB] rMyc[GST] is detectable
    *** cells: HELA in BMS "nuclear-extracts"
    *** source: 12660246-Fig-2a
  *** Taf5l[Ab] copptby[WB] Max[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 12660246-Fig-1a
  *** Taf5l[Ab] copptby[WB] xKat2a[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12660246-Fig-1a
  *** Taf7[Ab] snaggedby[WB] rMyc[GST] is undetectable
    *** cells: HELA in BMS "nuclear-extracts"
    *** source: 12660246-Fig-2a
  *** Taf9[Ab] copptby[WB] Max[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 12660246-Fig-1a
  *** Taf9[Ab] copptby[WB] xKat2a[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12660246-Fig-1a
  *** Taf9[Ab] copptby[WB] xMyc[tAb] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xMyc(111-439) [substitution]
    *** source: 12660246-Fig-1b
  *** Taf9[Ab] copptby[WB] xMyc[tAb] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xTrrap(1899-2401) [addition]
    *** source: 12660246-Fig-5d
  *** Taf9[Ab] snaggedby[WB] rMyc[GST] is detectable
    *** cells: HELA in BMS "nuclear-extracts"
    *** source: 12660246-Fig-2a
*** Tak1--
  *** xTak1(1-429)[Ab]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: HEK293<xTak1><xTab1> in BMS
    *** source: 10702308-Fig-5
  *** xTak1(K63W)[phosAb] phos(T187)[phosAb] is increased itpo (xTab1 + xTak1(1-303))
    *** cells: HELA<xTak1(K63W)> in BMS
    *** inhibited by: xTak1(T187A) [substitution]
    *** unaffected by: xTak1(S192A) [substitution]
    *** inhibited by: xTak1(T187A/S192A) [substitution]
    *** source: 15590691-Fig-3b
  *** xTak1(K63W)[tAb] copptby[WB] xNlk[tAb] is detectable
    *** cells: HEK293T<xNlk><xTab2><xTak1(K63W)> in BMS
    *** reqs: xTab2 [omission]
    *** source: 20194509-Fig-1a
  *** xTak1(K63W)[tAb] copptby[WB] xNlk[tAb] is detectable
    *** cells: HEK293T<xTak1(K63W)><xNlk><xTab2(178-693)> in BMS
    *** unaffected by: xTab2(292-693)"C2" [substitution]
    *** inhibited by: xTab2(417-693)"C3" [substitution]
    *** inhibited by: xTab2(477-693)"C4" [substitution]
    *** source: 20194509-Fig-S2
  *** xTak1(K63W)[tAb] copptby[WB] xTab2[tAb] is detectable
    *** cells: HEK293T<xNlk><xTab2><xTak1(K63W)> in BMS
    *** unaffected by: xTab2(del(292-417))"delM" [substitution]
    *** source: 20194509-Fig-1d
  *** xTak1(K63W)[tAb] copptby[WB] xTab2[tAb] is detectable
    *** cells: HEK293T<xTak1(K63W)><xTab2> in BMS
    *** source: 20194509-Fig-1a
  *** xTak1(K209R)[Ab] copptby[WB] Tab2[Ab] is detectable
    *** cells: mEFs<Tak1~null> in BMS
    *** inhibited by: xTak1(WT) [substitution]
    *** source: 19843958-Fig-S3
  *** xTak1(S192A)[Ab]IP IVKA(Mkk6)[32P-ATP] is increased itpo (xTab1 + xTak1(1-303))
    *** cells: HELA<xTak1(S192A)> in BMS
    *** unaffected by: xTak1(K63W)"KD" [substitution]
    *** inhibited by: xTak1(T187A) [substitution]
    *** inhibited by: xTak1(T187A/S192A) [substitution]
    *** source: 15590691-Fig-3b
  *** Tak1[Ab] copptby[WB] xNlk[tAb] is detectable
    *** cells: HEK293T<xNlk> in BMS
    *** enhanced by: xTab2 [addition]
    *** source: 20194509-Fig-1b
  *** Tak1[Ab] copptby[WB] xNlk[tAb] is detectable
    *** cells: HEK293T<xNlk> in BMS
    *** reqs: Tab2 [RNAi]
    *** source: 20194509-Fig-1c
  *** Tak1[Ab] copptby[WB] xNlk[tAb] is detectable
    *** cells: HEK293T<xNlk> in BMS
    *** source: 20194509-Fig-1e
  *** Tak1[Ab] phos[WBMS] is detectable
    *** cells: HEK293I1A<Irak1~null><xIrak1> in BMS
    *** reqs: xIrak1 [omission]
    *** unaffected by: xIrak1(K293A)"KD" [substitution]
    *** source: 11518704-Fig-6b
  *** xTak1[Ab]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: HEK293<xTak1><xTab1> in BMS
    *** inhibited by: xTak1(K63W)"KD" [substitution]
    *** inhibited by: xTak1(S192A) [substitution]
    *** source: 10702308-Fig-3c
  *** xTak1[Ab]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: HEK293<xTak1><xTab1> in BMS
    *** inhibited by: xTak1(K63W)"KD" [substitution]
    *** unaffected by: xTak1(1-429) [substitution]
    *** source: 10702308-Fig-5
  *** Tak1[Ab]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: HEK293I1A<Irak1~null><xIrak1> in BMS
    *** enhanced by: xIrak1(K293A)"KD" [substitution]
    *** source: 11259596-Fig-2
  *** Tak1[Ab]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: HEK293I1A<Irak1~null><xIrak1> in BMS
    *** reqs: xIrak1 [omission]
    *** inhibited by: xIrak1(K293A)"KD" [substitution]
    *** source: 11518704-Fig-6a
  *** Tak1[Ab]IP IVKA(Mkk6)[32P-ATP] is detectable
    *** cells: HEK293I1A<Irak1~null><xIrak1> in BMS
    *** reqs: xIrak1 [omission]
    *** enhanced by: xIrak1(K293A)"KD" [substitution]
    *** source: 11259596-Fig-2
  *** Tak1[Ab]IP IVKA(Mkk6)[32P-ATP] is detectable
    *** cells: mEFs in BMS
    *** reqs: Tab1 [KO]
    *** source: 12464436-Fig-5a
  *** xTak1[Ab]IP IVKA(Mkk6)[32P-ATP] is increased itpo (xTab1 + xTak1(1-303))
    *** cells: HELA<xTak1> in BMS
    *** inhibited by: xTak1(S192A) [substitution]
    *** source: 15590691-Fig-3b
  *** xTak1[Ab]IP IVKA(Mkk6)[32P-ATP] is increased itpo xTab1
    *** cells: HEK293<xTak1> in BMS
    *** comment: this is significantly stronger than response to xTab2
    *** source: 15590691-Fig-4b
  *** xTak1[Ab]IP IVKA(Mkk6)[32P-ATP] is increased itpo xTab1
    *** cells: HEK293<xTak1> in BMS
    *** inhibited by: xTak1(K63W)"KD" [substitution]
    *** inhibited by: xTak1(S192A) [substitution]
    *** source: 10702308-Fig-4a
  *** Tak1[Ab]IP IVKA(Mkk6)[32P-ATP] is increased itpo xTab1
    *** cells: HEK293<xTak1> in BMS
    *** source: 10702308-Fig-2
  *** xTak1[Ab]IP IVKA(Mkk6)[32P-ATP] is increased itpo xTab1
    *** cells: HELA<xTak1> in BMS
    *** inhibited by: xTak1(K63W)"KD" [substitution]
    *** inhibited by: xTak1(T187A) [substitution]
    *** inhibited by: xTak1(S192A) [substitution]
    *** source: 15590691-Fig-2a
  *** xTak1[Ab]IP IVKA(Mkk6)[32P-ATP] is increased itpo xTab2
    *** cells: HEK293<xTak1> in BMS
    *** comment: this is significantly weaker than response to xTab1
    *** source: 15590691-Fig-4b
  *** xTak1[Ab]IP phos(T184/T187)[phosAb] is increased itpo xTab1
    *** cells: HEK293T in BMS
    *** unaffected by: Tnf (10 min) [stim]
    *** unaffected by: xMekk3 [addition]
    *** unaffected by: xMekk3(S526A/K391M) [addition]
    *** source: 18206350-Fig-6a
  *** Tak1[Ab]IP phos[WBMS-PPase] is increased itpo xTab1
    *** cells: HEK293<xTak1> in BMS
    *** source: 10702308-Fig-2
  *** xTak1[Ab]IP phos[WBMS] is detectable
    *** cells: HEK293<xTak1><xTab1> in BMS
    *** inhibited by: xTak1(K63W)"KD" [substitution]
    *** inhibited by: xTak1(S192A) [substitution]
    *** source: 10702308-Fig-3b
  *** xTak1[Ab]IP ubiq[tUbAb] is decreased itpo xCyld
    *** cells: HEK293T<xUbiq(K63only)><xTab1> in BMS
    *** source: 19843958-Fig-S5b
  *** xTak1[Ab]IP ubiq[tUbAb] is decreased itpo xCyld
    *** cells: HEK293T<xUbiq><xTraf6> in BMS
    *** comment: lysates were boiled to remove noncovalently attached proteins before IP
    *** source: 19843958-Fig-1a
  *** xTak1[Ab]IP ubiq[tUbAb] is increased itpo xTraf6
    *** cells: HEK293T<xUbiq(K63only)> in BMS
    *** comment: lysates were boiled to remove noncovalently attached proteins before IP
    *** inhibited by: xTak1(K209R) [substitution]
    *** unaffected by: xTak1(K52R) [substitution]
    *** unaffected by: xTak1(K150R) [substitution]
    *** unaffected by: xTak1(K158R) [substitution]
    *** unaffected by: xTak1(K172R) [substitution]
    *** unaffected by: xTak1(K257R) [substitution]
    *** unaffected by: xTak1(K520R) [substitution]
    *** source: 19843958-Fig-1d
  *** xTak1[Ab]IP ubiq[tUbAb] is increased itpo xTraf6
    *** cells: HEK293T<xUbiq(K63only)> in BMS
    *** comment: lysates were boiled to remove noncovalently attached proteins before IP
    *** inhibited by: xTraf6(110-522)"T6dR" [substitution]
    *** source: 19843958-Fig-1a
  *** xTak1[Ab]IP ubiq[tUbAb] is increased itpo xTraf6
    *** cells: HEK293T<xUbiq> in BMS
    *** comment: lysates were boiled to remove noncovalently attached proteins before IP
    *** unaffected by: xUbiq(K63only) [substitution]
    *** partially inhibited by: xUbiq(K63R) [substitution]
    *** source: 19843958-Fig-1a
  *** xTak1[phosAb] phos(sitenr)[phosAb] is increased itpo xTab1
    *** cells: HEK293T<xTak1><xUbiq(K63only)> in BMS
    *** inhibited by: xTak1(K158R) [substitution]
    *** unaffected by: xTak1(K34R) [substitution]
    *** source: 20837137-Fig-2
  *** xTak1[phosAb] phos(T178)[phosAb] is detectable
    *** cells: HEK293T<xTak1><xTab1> in BMS
    *** inhibited by: xTak1(T178A) [substitution]
    *** inhibited by: xTak1(T184A) [substitution]
    *** inhibited by: xTak1(T178A/T184A) [substitution]
    *** source: 18617512-Fig-2c
  *** xTak1[phosAb] phos(T178/T184)[phosAb] is increased itpo xTab1
    *** cells: HEK293T<xTak1> in BMS
    *** partially inhibited by: xTak1(T178A) [substitution]
    *** partially inhibited by: xTak1(T184A) [substitution]
    *** inhibited by: xTak1(T178A/T184A) [substitution]
    *** source: 18617512-Fig-2a
  *** xTak1[phosAb] phos(T184)[phosAb] is detectable
    *** cells: Ecoli<xTab1> in BugMedium
    *** inhibited by: xTak1(K63W) [substitution]
    *** unaffected by: xTak1(T178A) [substitution]
    *** enhanced by: xTak1(T178E) [substitution]
    *** inhibited by: xTak1(T184A) [substitution]
    *** inhibited by: xTak1(T184E) [substitution]
    *** inhibited by: xTak1(T187A) [substitution]
    *** unaffected by: xTak1(T187E) [substitution]
    *** inhibited by: xTak1(S192A) [substitution]
    *** inhibited by: xTak1(S192E) [substitution]
    *** source: 20538596-Fig-6
  *** xTak1[phosAb] phos(T184)[phosAb] is detectable
    *** cells: HEK293T<xTak1><xTab1> in BMS
    *** unaffected by: xTak1(T178A) [substitution]
    *** inhibited by: xTak1(T184A) [substitution]
    *** source: 18617512-Fig-2b
  *** xTak1[phosAb] phos(T184)[phosAb] is increased itpo xTab1
    *** cells: Ecoli in BugMedium
    *** partially inhibited by: xTab2 [addition]
    *** source: 20538596-Fig-1a
  *** xTak1[phosAb] phos(T184)[phosAb] is unchanged itpo xTab2
    *** cells: Ecoli in BugMedium
    *** source: 20538596-Fig-1a
  *** xTak1[phosAb] phos(T184/T187)[phosAb] is detectable
    *** cells: Ecoli<xTab1> in BugMedium
    *** inhibited by: xTak1(K63W) [substitution]
    *** unaffected by: xTak1(T178A) [substitution]
    *** enhanced by: xTak1(T178E) [substitution]
    *** inhibited by: xTak1(T184A) [substitution]
    *** inhibited by: xTak1(T184E) [substitution]
    *** inhibited by: xTak1(T187A) [substitution]
    *** inhibited by: xTak1(T187E) [substitution]
    *** inhibited by: xTak1(S192A) [substitution]
    *** inhibited by: xTak1(S192E) [substitution]
    *** source: 20538596-Fig-6
  *** rTak1[phosAb] phos(T184/T187)[phosAb] is detectable
    *** cells: none
    *** comment: reaction also contains rTab1
    *** inhibited by: rTak1(K63W) [substitution]
    *** inhibited by: rTak1(A236E/M240E)"AM" [substitution]
    *** inhibited by: rTak1(F237E/W241E)"FW" [substitution]
    *** inhibited by: rTak1(W241E/V243E)"WV" [substitution]
    *** inhibited by: rTak1(I239E/V243E)"IV" [substitution]
    *** source: 20538596-Fig-5e
  *** rTak1[phosAb] phos(T184/T187)[phosAb] is detectable
    *** cells: none
    *** comment: reaction also contains rTab1
    *** inhibited by: rTak1(K63W) [substitution]
    *** inhibited by: rTak1(A236K/M240K)"AM" [substitution]
    *** inhibited by: rTak1(F237K/W241K)"FW" [substitution]
    *** inhibited by: rTak1(W241K/V243K)"WV" [substitution]
    *** inhibited by: rTak1(I239K/V243K)"IV" [substitution]
    *** source: 20538596-Fig-5e
  *** rTak1[phosAb] phos(T184/T187)[phosAb] is detectable
    *** cells: none
    *** comment: reaction also contains rTab1
    *** unaffected by: 5Z7Oxozeaenol [addition]
    *** source: 20538596-Fig-2d
  *** xTak1[phosAb] phos(T184/T187)[phosAb] is increased itpo xTab1
    *** cells: Ecoli in BugMedium
    *** partially inhibited by: xTab2 [addition]
    *** source: 20538596-Fig-1a
  *** xTak1[phosAb] phos(T184/T187)[phosAb] is increased itpo xTab1
    *** cells: HEK293T in BMS
    *** unaffected by: xTiprl [addition]
    *** unaffected by: xIgbp1 [addition]
    *** source: 18456659-Fig-1a
  *** xTak1[phosAb] phos(T184/T187)[phosAb] is unchanged itpo xTab2
    *** cells: Ecoli in BugMedium
    *** source: 20538596-Fig-1a
  *** Tak1[phosAb] phos(T187)[phosAb] is decreased itpo xEgfR
    *** cells: HEK293<xTab1><xTab2> in BMS
    *** reversed by: xTab1(T431A/S432A) [substitution]
    *** source: 19393267-Fig-5f
  *** xTak1[phosAb] phos(T187)[phosAb] is detectable
    *** cells: Ecoli<xTab1> in BugMedium
    *** inhibited by: xTak1(K63W) [substitution]
    *** unaffected by: xTak1(T178A) [substitution]
    *** enhanced by: xTak1(T178E) [substitution]
    *** inhibited by: xTak1(T184A) [substitution]
    *** inhibited by: xTak1(T184E) [substitution]
    *** inhibited by: xTak1(T187A) [substitution]
    *** unaffected by: xTak1(T187E) [substitution]
    *** inhibited by: xTak1(S192A) [substitution]
    *** inhibited by: xTak1(S192E) [substitution]
    *** source: 20538596-Fig-6
  *** xTak1[phosAb] phos(T187)[phosAb] is detectable
    *** cells: mMesangialCells<xTak1><xTgfbR1> in BMS
    *** inhibited by: xTak1(K34R)"ubiq-site-mut" [substitution]
    *** source: 19556242-Fig-7c
  *** xTak1[phosAb] phos(T187)[phosAb] is detectable
    *** cells: mMesangialCells<xTak1><xTgfbR1> in BMS
    *** inhibited by: xTak1(mnr)"del-Cterm" [substitution]
    *** source: 19556242-Fig-8c
  *** Tak1[phosAb] phos(T187)[phosAb] is detectable
    *** cells: THP1 in BMS
    *** partially reqs: Ampka1 [RNAi]
    *** source: 22833096-Fig-2f
  *** Tak1[phosAb] phos(T187)[phosAb] is detectable
    *** cells: THP1 in BMS
    *** reqs: Ampka1 [RNAi]
    *** source: 22833096-Fig-2g
  *** Tak1[phosAb] phos(T187)[phosAb] is increased itao Ppp6c [RNAi]
    *** cells: HEK293<xIL1R1> in BMS
    *** source: 17079228(D)
  *** xTak1[phosAb] phos(T187)[phosAb] is increased itpo xTab1
    *** cells: Ecoli in BugMedium
    *** partially inhibited by: xTab2 [addition]
    *** source: 20538596-Fig-1a
  *** xTak1[phosAb] phos(T187)[phosAb] is increased itpo xTab1
    *** cells: HEK293 in BMS
    *** inhibited by: xTak1(K63W)"KD" [substitution]
    *** source: 16260783(D)
  *** xTak1[phosAb] phos(T187)[phosAb] is increased itpo xTab1
    *** cells: HEK293 in BMS
    *** unaffected by: xMekk3 [addition]
    *** inhibited by: xTak1(K63A)"KD" [substitution]
    *** source: 16260783-Fig-5a
  *** xTak1[phosAb] phos(T187)[phosAb] is increased itpo xTab1
    *** cells: HEK293 in BMS
    *** unaffected by: xMekk3 [addition]
    *** inhibited by: xTak1(K63A)"KD" [substitution]
    *** source: 16260783-Fig-7c
  *** xTak1[phosAb] phos(T187)[phosAb] is increased itpo xTab1
    *** cells: HEK293<xTak1> in BMS
    *** comment: this is significantly stronger than response to xTab2
    *** source: 15590691-Fig-4b
  *** xTak1[phosAb] phos(T187)[phosAb] is increased itpo xTab1
    *** cells: HEK293T in BMS
    *** unaffected by: xTak1(K172D) [substitution]
    *** unaffected by: xTak1(K209D) [substitution]
    *** inhibited by: xTak1(K63D) [substitution]
    *** source: 19843958-Fig-S6
  *** xTak1[phosAb] phos(T187)[phosAb] is increased itpo xTab1
    *** cells: HEK293T<xTak1> in BMS
    *** inhibited by: xTak1(K158R) [substitution]
    *** unaffected by: xTak1(K150R) [substitution]
    *** inhibited by: xTak1(K63R) [substitution]
    *** source: 20038579-Fig-4e
  *** xTak1[phosAb] phos(T187)[phosAb] is increased itpo xTab1
    *** cells: HEK293T<xUbiq(K63only)> in BMS
    *** unaffected by: xCyld [addition]
    *** source: 19843958-Fig-S5b
  *** xTak1[phosAb] phos(T187)[phosAb] is increased itpo xTab1
    *** cells: HELA<xTak1> in BMS
    *** inhibited by: xTak1(T187A) [substitution]
    *** inhibited by: xTak1(S192A) [substitution]
    *** inhibited by: xTak1(K63W)"KD" [substitution]
    *** source: 15590691-Fig-2a
  *** xTak1[phosAb] phos(T187)[phosAb] is increased itpo xTab1
    *** cells: HELA<xTak1> in BMS
    *** unaffected by: xTak1(1-303) [substitution]
    *** source: 15590691-Fig-3a
  *** xTak1[phosAb] phos(T187)[phosAb] is increased itpo xTab1
    *** cells: mEFs in BMS
    *** does not req: Mekk3 [KO]
    *** source: 19843958-Fig-S5
  *** xTak1[phosAb] phos(T187)[phosAb] is increased itpo xTab1
    *** cells: mMesangialCells<xTak1> in BMS
    *** unaffected by: xTak1(K34R)"ubiq-site-mut" [substitution]
    *** source: 19556242-Fig-7c
  *** xTak1[phosAb] phos(T187)[phosAb] is increased itpo xTab2
    *** cells: HEK293 in BMS
    *** inhibited by: xTak1(K63W)"KD" [substitution]
    *** inhibited by: xTak1(T187A) [substitution]
    *** source: 15590691-Fig-4a
  *** xTak1[phosAb] phos(T187)[phosAb] is increased itpo xTab2
    *** cells: HEK293<xTak1> in BMS
    *** comment: this is significantly weaker than response to xTab1
    *** source: 15590691-Fig-4b
  *** xTak1[phosAb] phos(T187)[phosAb] is increased itpo xTgfbR1
    *** cells: mMesangialCells<xTak1> in BMS
    *** inhibited by: xTgfbR2 [addition]
    *** source: 19556242-Fig-4b
  *** xTak1[phosAb] phos(T187)[phosAb] is increased itpo xTgfbR1
    *** cells: mMesangialCells<xTak1> in BMS
    *** inhibited by: xTgfbR2 [addition]
    *** source: 19556242-Fig-5b
  *** xTak1[phosAb] phos(T187)[phosAb] is increased itpo xTgfbR1
    *** cells: mMesangialCells<xTak1> in BMS
    *** unaffected by: xTgfbR1(T185V/T186V/S187A/S189A/S191A)"GS" [substitution]
    *** unaffected by: xTgfbR1(1-255)"LC" [substitution]
    *** inhibited by: xTgfbR1(1-151)"SC" [substitution]
    *** unaffected by: xTgfbR1(T198D)"CA" [substitution]
    *** source: 19556242-Fig-3a
  *** xTak1[phosAb] phos(T187)[phosAb] is unchanged itpo xTab2
    *** cells: Ecoli in BugMedium
    *** source: 20538596-Fig-1a
  *** Tak1[phosAb] phos(T187/S192)[phosAb] is detectable
    *** cells: mEFs in BMS
    *** reqs: Traf6 [KO]
    *** source: 18758450-Fig-5a
  *** Tak1[phosAb] phos(T187/S192)[phosAb] is detectable
    *** cells: mEFs<xTraf6> in BMS
    *** inhibited by: xTraf6(C70A) [substitution]
    *** source: 18758450-Fig-5b
  *** xTak1[phosAb] phos(T187/S192)[phosAb] is increased itpo xTab1
    *** cells: HEK293T<xTak1> in BMS
    *** source: 18758450-Fig-S1b
  *** xTak1[tAb] copptby[WB] xAmpka1[tAb] is detectable
    *** cells: HEK293<xAmpka1><xTak1> in BMS
    *** unaffected by: xTak1(1-500) [substitution]
    *** unaffected by: xTak1(1-400) [substitution]
    *** unaffected by: xTak1(1-300) [substitution]
    *** partially inhibited by: xTak1(1-200) [substitution]
    *** inhibited by: xTak1(1-100) [substitution]
    *** source: 22833096-Fig-2b
  *** xTak1[tAb] copptby[WB] xNemo[tAb] is detectable
    *** cells: HEK293<xTak1><xNemo> in BMLS
    *** unaffected by: xTak1(K34R) [substitution]
    *** source: 22069318-Fig-3d
  *** xTak1[tAb] copptby[WB] xTraf2[tAb] is increased itpo xTab3
    *** cells: HEK293 in BMS
    *** inhibited by: xTab3(del(478-661)) [substitution]
    *** source: 14633987-Fig-4d
  *** xTak1[tAb] copptby[WB] xTraf6[tAb] is increased itpo xTab3
    *** cells: HEK293 in BMS
    *** inhibited by: xTab3(del(478-661)) [substitution]
    *** source: 14633987-Fig-4d
  *** xTak1[tAb] oligomerization[2TagPpt] is detectable
    *** cells: HEK293T<xTak1> in BMS
    *** source: 18758450-Fig-2c
  *** xTak1[tAb] oligomerization[2TagPpt] is detectable
    *** cells: mEFs<Ampka1~null><Ampka2~null><xTak1> in BMS
    *** source: 20538596-Fig-5a
  *** rTak1[tAb] oligomerization[2TagPpt] is detectable
    *** cells: none
    *** source: 18758450-Fig-S3c
  *** xTak1[tAb] phos[WBMS] is increased itpo xTab1
    *** cells: HEK293<xIL1R1> in BMS
    *** enhanced by: xTiprl [addition]
    *** unaffected by: xTiprl(F254A/P255A) [addition]
    *** source: 18456659-Fig-4b
  *** xTak1[tAb] phos[WBMS] is increased itpo xTab1
    *** cells: HEK293<xIL1R1> in BMS
    *** inhibited by: xTak1(K63W) [substitution]
    *** source: 18456659-Fig-4b
  *** xTak1[tAb] ubiq[tUbAb-ppt] is increased itpo xTab1
    *** cells: HEK293T<xTak1><xUbiq> in BMS
    *** inhibited by: xTak1(K63R) [substitution]
    *** source: 20038579-Fig-2a
  *** xTak1[tAb]IP boundby[FarWestern] rTiprl[GST] is detectable
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** source: 18456659-Fig-3b
  *** xTak1[tAb]IP boundby[FarWestern] rTiprl[GST] is detectable
    *** cells: none
    *** IPfrom: HEK293T<xTab1> in BMS
    *** source: 18456659-Fig-3
  *** xTak1[tAb]IP boundby[FarWestern] rTiprl[GST] is undetectable
    *** cells: none
    *** IPfrom: HEK293T<xTab1><xTiprl> in BMS
    *** source: 18456659-Fig-3b
  *** xTak1[tAb]IP IVKA(Ikk2)[32P-ATP] is increased itpo xTab1
    *** cells: HEK293T in BMS
    *** enhanced by: xTiprl [addition]
    *** inhibited by: xTiprl(F254A) [addition]
    *** inhibited by: xTiprl(F254A/P255A) [addition]
    *** source: 18456659-Fig-6b
  *** xTak1[tAb]IP IVKA(Mkk6)(S207)[phosAb] is unchanged by rTraf6{ubiq}
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** comment: xTak1[tAb]IP was shown to contain Tab1 and Tab2
    *** comment: rTraf6 was ubiquitinated with (rUbiq + pUbe1 + rUbe2d3) followed by inactivation of E1 and E2 with NEM
    *** source: 19675569-Fig-S6b
  *** xTak1[tAb]IP IVKA(Mkk6)(S207)[phosAb] is unchanged by rUbiq{K48poly}
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** comment: xTak1[tAb]IP was shown to contain Tab1 and Tab2
    *** comment: rUbiq was polymerized with (pUbe1 + rCdc34 + (rSkp1 + rCul1 + rRbx1 + rBtrc))
    *** source: 19675569-Fig-2f
  *** xTak1[tAb]IP IVKA(Mkk6)(S207)[phosAb] is unchanged by rUbiq{poly2}
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** comment: xTak1[tAb]IP was shown to contain Tab1 and Tab2
    *** comment: rUbiq was polymerized with (pUbe1 + rUbe2d3 + rTraf6)
    *** source: 19675569-Fig-S10c
  *** xTak1[tAb]IP IVKA(Mkk6)(S207)[phosAb] is unchanged by rUbiq{poly3}
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** comment: xTak1[tAb]IP was shown to contain Tab1 and Tab2
    *** comment: rUbiq was polymerized with (pUbe1 + rUbe2d3 + (rRnf31 + rRbck1))
    *** source: 19675569-Fig-S10c
  *** xTak1[tAb]IP IVKA(Mkk6)(sitenr)[phosAb] is increased itpo xTab1
    *** cells: HEK293T<xTak1> in BMS
    *** inhibited by: xTak1(K158R) [substitution]
    *** unaffected by: xTak1(K150R) [substitution]
    *** inhibited by: xTak1(K63R) [substitution]
    *** source: 20038579-Fig-4e
  *** xTak1[tAb]IP IVKA(Mkk6)[32P-ATP] is decreased by pPP2a
    *** cells: none
    *** IPfrom: HEK293<xTab1> in BMS
    *** source: 17079228(D)
  *** xTak1[tAb]IP IVKA(Mkk6)[32P-ATP] is increased itpo xTab1
    *** cells: HEK293 in BMS
    *** inhibited by: xTak1(K63W)"KD" [substitution]
    *** source: 10094049-Fig-2a
  *** xTak1[tAb]IP IVKA(Mkk6)[32P-ATP] is increased itpo xTab1
    *** cells: HEK293T in BMS
    *** enhanced by: xTiprl [addition]
    *** enhanced by: xTiprl(F254A) [addition]
    *** enhanced by: xTiprl(F254A/P255A) [addition]
    *** source: 18456659-Fig-6b
  *** xTak1[tAb]IP IVKA(Mkk6)[32P-ATP] is increased itpo xTab1
    *** cells: HELA in BMS
    *** inhibited by: xTab1(1-436)"Nterm" [substitution]
    *** unaffected by: xTab1(437-504)"Cterm" [substitution]
    *** source: 10838074-Fig-3
  *** xTak1[tAb]IP IVKA(Mkk6)[32P-ATP] is increased itpo xTab1
    *** cells: HELA in BMS
    *** inhibited by: xTak1(K63W) [substitution]
    *** source: 10838074-Fig-1
  *** xTak1[tAb]IP IVKA(Mkk6)[32P-ATP] is increased itpo xTab1
    *** cells: HELA in BMS
    *** unaffected by: xTak1(23-606) [substitution]
    *** partially inhibited by: xTak1(T184E/T187E) [substitution]
    *** source: 10838074-Fig-1
  *** xTak1[tAb]IP IVKA(Mkk6)[32P-ATP] is increased itpo xTab1(437-504)"Cterm"
    *** cells: HELA in BMS
    *** inhibited by: xTab1(437-460)"C1" [substitution]
    *** inhibited by: xTab1(459-482)"C2" [substitution]
    *** partially inhibited by: xTab1(480-504)"C3" [substitution]
    *** source: 10838074-Fig-4a
  *** xTak1[tAb]IP IVKA(Mkk6)[32P-ATP] is increased itpo xTab2
    *** cells: HEK293 in BMS
    *** source: 10882101(D)
  *** xTak1[tAb]IP IVKA(Mkk6)[32P-ATP] is increased itpo xTab2
    *** cells: HEK293 in BMS
    *** source: 14633987-Fig-2b
  *** xTak1[tAb]IP IVKA(Mkk6)[32P-ATP] is increased itpo xTab2
    *** cells: HEK293 in BMS
    *** unaffected by: xSmad7 [addition]
    *** source: 17384642-Fig-5b
  *** xTak1[tAb]IP IVKA(Mkk6)[32P-ATP] is increased itpo xTab3
    *** cells: HEK293 in BMS
    *** source: 14633987-Fig-2b
  *** xTak1[tAb]IP IVKA(Mkk6)[32P-ATP] is unchanged itpo xTab1
    *** cells: HELA<xTak1> in BMS
    *** inhibited by: xTab1(1-436)"Nterm" [substitution]
    *** unaffected by: xTab1(437-504)"Cterm" [substitution]
    *** inhibited by: xTab1(481-504)"C3" [substitution]
    *** source: 15590691-Fig-8b
  *** xTak1[tAb]IP phos(T187)[phosAb] is decreased by pPP2a
    *** cells: none
    *** IPfrom: HEK293<xTab1> in BMS
    *** source: 17079228(D)
  *** xTak1[tAb]IP phos(T187)[phosAb] is increased itpo xTab1
    *** cells: HELA<xTak1> in BMS
    *** inhibited by: xTab1(1-436)"Nterm" [substitution]
    *** enhanced by: xTab1(437-504)"Cterm" [substitution]
    *** unaffected by: xTab1(481-504)"C3" [substitution]
    *** source: 15590691-Fig-8b
  *** xTak1[tAb]IP phos[WBMS] is increased itpo xTab1
    *** cells: HELA in BMS
    *** inhibited by: xTab1(1-436)"Nterm" [substitution]
    *** unaffected by: xTab1(437-504)"Cterm" [substitution]
    *** source: 10838074-Fig-3
  *** xTak1[tAb]IP phos[WBMS] is increased itpo xTab1
    *** cells: HELA in BMS
    *** partially inhibited by: xTak1(23-606) [substitution]
    *** partially inhibited by: xTak1(T184E/T187E) [substitution]
    *** inhibited by: xTak1(K63W) [substitution]
    *** source: 10838074-Fig-1
  *** xTak1[tAb]IP phos[WBMS] is increased itpo xTab1(437-504)"Cterm"
    *** cells: HELA in BMS
    *** inhibited by: xTab1(437-460)"C1" [substitution]
    *** inhibited by: xTab1(459-482)"C2" [substitution]
    *** partially inhibited by: xTab1(480-504)"C3" [substitution]
    *** source: 10838074-Fig-4a
  *** xTak1[tAb]IP phos[WBMS] is increased itpo xTiprl
    *** cells: HEK293T<xTab1> in BMS
    *** comment: both basal and increased upshift are decreased by treatment of lysates with PPase
    *** source: 18456659-Fig-1b
  *** xTak1[tAb]IP ubiq[tUbAb] is detectable
    *** cells: HEK293<xIL1R1><xTak1><xUbiq> in BMLS
    *** inhibited by: xTak1(K34R) [substitution]
    *** comment: lysates were boiled in 1% SDS to remove noncovalently attached proteins before IP
    *** source: 22069318-Fig-3a
  *** xTak1[tAb]IP ubiq[tUbAb] is increased itpo xTab1
    *** cells: HEK293T<xTak1><xUbiq(K63only)> in BMS
    *** inhibited by: xTak1(K158R) [substitution]
    *** unaffected by: xTak1(K34R) [substitution]
    *** source: 20837137-Fig-1a
  *** xTak1[tAb]IP ubiq[tUbAb] is increased itpo xTab1
    *** cells: HEK293T<xTak1><xUbiq(K63only)> in BMS
    *** inhibited by: xUbiq(K48only) [substitution]
    *** source: 20038579-Fig-2b
  *** xTak1[tAb]IP ubiq[tUbAb] is increased itpo xTab1
    *** cells: HEK293T<xTak1><xUbiq> in BMS
    *** inhibited by: xTak1(K63R) [substitution]
    *** source: 20038579-Fig-2a
  *** xTak1[tAb]IP ubiq[tUbAb] is increased itpo xTab1
    *** cells: HEK293T<xTak1><xUbiq> in BMS
    *** unaffected by: xTak1(1-338) [substitution]
    *** unaffected by: xTak1(1-290) [substitution]
    *** source: 20038579-Fig-3b
  *** xTak1[tAb]IP ubiq[tUbAb] is increased itpo xTab1
    *** cells: HEK293T<xTak1><xUbiq> in BMS
    *** unaffected by: xTak1(K34R) [substitution]
    *** unaffected by: xTak1(K52R/K54R) [substitution]
    *** unaffected by: xTak1(K58R) [substitution]
    *** inhibited by: xTak1(K63R) [substitution]
    *** unaffected by: xTak1(K72R) [substitution]
    *** unaffected by: xTak1(K91R) [substitution]
    *** unaffected by: xTak1(K150R) [substitution]
    *** inhibited by: xTak1(K158R) [substitution]
    *** unaffected by: xTak1(K172R) [substitution]
    *** unaffected by: xTak1(K190R) [substitution]
    *** unaffected by: xTak1(K209R) [substitution]
    *** unaffected by: xTak1(K227R) [substitution]
    *** unaffected by: xTak1(K253R) [substitution]
    *** unaffected by: xTak1(K257R) [substitution]
    *** unaffected by: xTak1(K269R) [substitution]
    *** unaffected by: xTak1(K282R) [substitution]
    *** source: 20038579-Fig-3d
  *** xTak1[tAb]IP ubiq[tUbAb] is increased itpo xTraf2
    *** cells: HEK293T<xTak1><xUbiq> in BMS
    *** inhibited by: xUbiq(K48only) [substitution]
    *** unaffected by: xUbiq(K63only) [substitution]
    *** source: 20038579-Fig-5a
  *** xTak1[tAb]IP ubiq[tUbAb] is increased itpo xTraf6
    *** cells: HEK293T<xTak1><xUbiq(K63only)> in BMS
    *** inhibited by: xTak1(K158R) [substitution]
    *** unaffected by: xTak1(K34R) [substitution]
    *** source: 20837137-Fig-1b
  *** xTak1[tAb]IP ubiq[tUbAb] is increased itpo xTraf6
    *** cells: HEK293T<xTak1><xUbiq> in BMS
    *** inhibited by: xUbiq(K48only) [substitution]
    *** unaffected by: xUbiq(K63only) [substitution]
    *** source: 20038579-Fig-5b
  *** xTak1[tAb]IP ubiq[tUbAb] is increased itpo xUbiq
    *** cells: HEK293T<xTak1> in BMS
    *** unaffected by: xTgfbR1(mnr)"CA" [addition]
    *** unaffected by: xTgfbR1(mnr)"KD" [addition]
    *** source: 18758450-Fig-S3b
  *** xTak1[tAb]IP ubiq[UbAb] is detectable
    *** cells: HELA<xTak1> in BMS
    *** inhibited by: xTak1(K158R) [substitution]
    *** source: 20038579-Fig-4a
  *** xTak1{ubiq}[tAb] snaggedby[WB] rNemo[GST] is detectable
    *** cells: HEK293T<xTak1><xTab1><xUbiq> in BMS
    *** inhibited by: xTak1(K158R) [substitution]
    *** source: 20038579-Fig-6a
*** Tank--
  *** xTank(1-190)[tAb] copptby[WB] xTbk1(689-729)[GST] is detectable
    *** cells: HEK293 in BMS
    *** source: 10581243-Fig-7a
  *** xTank(1-190)[tAb] copptby[WB] xTbk1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 10581243-Fig-7a
  *** rTank[32P] phos[32P-ATP] is increased by xIkke[tAb]IP
    *** cells: none
    *** IPfrom: COS7 in BMS
    *** source: 10759890-Fig-2c
  *** Tank[Ab] copptby[WB] xTradd[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 18439848-Fig-3d
  *** xTank[tAb] copptby[WB] xIkk1[tAb] is detectable
    *** cells: HEK293<xIkke> in BMS
    *** reqs: xIkke [omission]
    *** source: 12133833-Fig-5b
  *** xTank[tAb] copptby[WB] xIkke[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 10759890-Fig-1a
  *** xTank[tAb] copptby[WB] xNemo[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 12133833-Fig-2c
  *** xTank[tAb] copptby[WB] xNemo[Ab] is detectable
    *** cells: HEK293<xIkke> in BMS
    *** reqs: xIkke [omission]
    *** unaffected by: xIkke(K38A)"KD" [substitution]
    *** source: 12133833-Fig-5a
  *** xTank[tAb] copptby[WB] xNemo[tAb] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xTank(1-415) [substitution]
    *** inhibited by: xTank(1-410) [substitution]
    *** inhibited by: xTank(1-405) [substitution]
    *** inhibited by: xTank(1-390) [substitution]
    *** inhibited by: xTank(1-375) [substitution]
    *** source: 16336209-Fig-1b
  *** xTank[tAb] copptby[WB] xNemo[tAb] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xTank(del(170-191)) [substitution]
    *** source: 16336209-Fig-1c
  *** xTank[tAb] copptby[WB] xNemo[tAb] is detectable
    *** cells: HEK293 in BMS
    *** partially inhibited by: xIkk2 [addition]
    *** comment: coppt Tank is unphosphorylated [WBMS]
    *** source: 16336209-Fig-6
  *** xTank[tAb] copptby[WB] xTbk1(689-729)[GST] is detectable
    *** cells: HEK293 in BMS
    *** source: 10581243-Fig-7a
  *** xTank[tAb] copptby[WB] xTbk1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 10581243-Fig-7a
  *** xTank[tAb] copptby[WB] xTraf2[tAb] is detectable
    *** cells: HEK293 in BMS
    *** partially inhibited by: xIkke [addition]
    *** partially inhibited by: xIkke(K38A) [addition]
    *** source: 10759890-Fig-7a
  *** xTank[tAb] copptby[WB] xTraf2[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 10759890-Fig-4b
  *** xTank[tAb] copptby[WB] xTraf6[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 10759890-Fig-4b
  *** xTank[tAb] oligomerization[2TagPpt] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: xTank(del(170-191)) [substitution]
    *** source: 16336209-Fig-1d
  *** xTank[tAb] phos[WBMS-PPase] is increased itpo xNemo
    *** cells: HEK293 in BMS
    *** enhanced by: xIkk2 [addition]
    *** source: 16336209-Fig-2a,2b
  *** xTank[tAb]IP IVKA(auto)[32P-ATP] is increased itpo xIkke
    *** cells: HEK293 in BMS
    *** source: 16336209-Fig-2c
  *** xTank[tAb]IP IVKA(auto)[32P-ATP] is increased itpo xNemo
    *** cells: HEK293 in BMS
    *** enhanced by: xIkk2 [addition]
    *** source: 16336209-Fig-2c
  *** xTank[tAb]IP phos[WBMS] is increased itpo xIkke
    *** cells: HEK293<xTraf2> in BMS
    *** inhibited by: xIkke(K38A) [substitution]
    *** source: 10759890-Fig-7b
*** Tax1bp1--
  *** rTax1bp1(205-599)[32P] phos[32P-ATP] is increased by rIkk1(mnr)"CA"
    *** cells: none
    *** source: 21765415-Fig-1f
  *** rTax1bp1(205-599)[32P] phos[32P-ATP] is unchanged by rIkk2(mnr)"CA"
    *** cells: none
    *** source: 21765415-Fig-1f
  *** Tax1bp1[Ab] copptby[WB] xTnfaip3[tAb] is detectable
    *** cells: mEFs<Tnfaip3~null><xTnfaip3> in BMS "treated with IL1 for 30-60 min"
    *** unaffected by: xTnfaip3(547-775) [substitution]
    *** inhibited by: xTnfaip3(del(247-699)) [substitution]
    *** source: 20185725-Fig-4f
  *** xTax1bp1[phosAb] phos(S593)[phosAb] is increased itpo xIkk1
    *** cells: HEK293<xTax1bp1> in BMS
    *** inhibited by: xTax1bp1(S593A) [substitution]
    *** source: 21765415-Fig-2i
  *** xTax1bp1[tAb] phos[WBMS] is increased itpo xIkk1
    *** cells: HEK293<xTax1bp1> in BMS
    *** unaffected by: xTax1bp1(S593A) [substitution]
    *** source: 21765415-Fig-2e
  *** xTax1bp1[tAb] phos[WBMS] is increased itpo xIkk1
    *** cells: mEFs<xTax1bp1> in BMS
    *** source: 21765415-Fig-1d
  *** xTax1bp1[tAb] phos[WBMS] is increased itpo xIkk2
    *** cells: mEFs<xTax1bp1> in BMS
    *** source: 21765415-Fig-1d
  *** xTax1bp1[tAb] phos[WBMS] is unchanged itpo xNemo
    *** cells: mEFs<xTax1bp1> in BMS
    *** source: 21765415-Fig-1d
*** Tbc1d4--
  *** Tbet-gene mRNA[RTPCR] is detectable
    *** cells: mSpCD4TCs in BMS "pretreated with anti-Cd3 + anti-Cd28 + IL12 for 5 days"
    *** does not req: Stat6 [KO]
    *** source: 19324016-Fig-3c
  *** Tbet[Ab] prot-exp[WB] is detectable
    *** cells: hCBLs<Cd4~pos> in BMS "treated with anti-Cd3/anti-Cd28 for 24 hr"
    *** inhibited by: anti-Ifng [cotreatment]
    *** enhanced by: IL12 [cotreatment]
    *** enhanced by: IL12 + anti-Ifng [cotreatment]
    *** enhanced by: anti-IL12 + Ifng [cotreatment]
    *** inhibited by: IL4 [cotreatment]
    *** source: 16220539-Fig-2b
  *** Tbet[Ab] prot-exp[WB] is detectable
    *** cells: hCBLs<Cd4~pos> in BMS "treated with anti-Cd3/anti-Cd28 for 48 hr"
    *** inhibited by: anti-Ifng [cotreatment]
    *** enhanced by: IL12 [cotreatment]
    *** unaffected by: IL12 + anti-Ifng [cotreatment]
    *** unaffected by: anti-IL12 + Ifng [cotreatment]
    *** inhibited by: IL4 [cotreatment]
    *** source: 16220539-Fig-2b
*** Tbk1--
  *** Tbk1[Ab] copptby[WB] Ikk2[Ab] is undetectable
    *** cells: HEK293 in BMS
    *** unaffected by: Tnf (10 min) [stim]
    *** source: 10990461-Fig-1b
  *** Tbk1[Ab] copptby[WB] Traf2[Ab] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: Tnf (10 min) [stim]
    *** source: 10990461-Fig-1b
  *** Tbk1[Ab] copptby[WB] Traf6[Ab] is undetectable
    *** cells: HEK293 in BMS
    *** unaffected by: Tnf (10 min) [stim]
    *** source: 10990461-Fig-1b
  *** Tbk1[Ab] infraction(P100)[WB] is detectable
    *** cells: HELA in BMLS
    *** source: 21464307-Fig-5c
  *** Tbk1[Ab] infraction(P100)[WB] is detectable
    *** cells: HELA in BMS
    *** source: 21464307-Fig-5c
  *** Tbk1[Ab] infraction(P100)[WB] is detectable
    *** cells: MDCK2 in BMS
    *** source: 21464307-Fig-5c
  *** Tbk1[Ab]IP IVKA(Akt1)(S473)[phosAb] is detectable
    *** cells: HELA in BMS
    *** unaffected by: LY294002 [pretreatment]
    *** unaffected by: Wortmannin [pretreatment]
    *** unaffected by: Rapamycin [pretreatment]
    *** source: 21464307-Fig-5b
  *** Tbk1[Ab]IP IVKA(Akt1)(S473)[phosAb] is detectable
    *** cells: HELA<xIkke> in BMS
    *** unaffected by: xIkke(mnr)"KD" [substitution]
    *** source: 21464307-Fig-S5c
  *** Tbk1[Ab]IP IVKA(Akt1)(T308)[phosAb] is detectable
    *** cells: HELA in BMS
    *** unaffected by: LY294002 [pretreatment]
    *** unaffected by: Wortmannin [pretreatment]
    *** unaffected by: Rapamycin [pretreatment]
    *** source: 21464307-Fig-5b
  *** xTbk1[tAb] copptby[WB] xIrf3[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12692549-Fig-2d
  *** xTbk1[tAb] copptby[WB] xMavs[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 16127453-Fig-5b
  *** xTbk1[tAb] copptby[WB] xMavs[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 16177806-Fig-3a
  *** xTbk1[tAb] copptby[WB] xNemo[Ab] is detectable
    *** cells: HEK293<xTank> in BMS
    *** reqs: xTank [omission]
    *** unaffected by: xTbk1(K38A)"KD" [substitution]
    *** source: 12133833-Fig-5b
  *** xTbk1[tAb] copptby[WB] xTraf3[Ab] is detectable
    *** cells: HEK293T in BMS
    *** source: 16306936-Fig-2c
  *** xTbk1[tAb] copptby[WB] xTrif(mnr)"delC"[tAb] is detectable
    *** cells: HEK293<xTrif(mnr)"delC"><xTbk1> in BMS
    *** inhibited by: xTraf6(mnr)"T6CT" [addition]
    *** source: 14530355-Fig-5a
  *** xTbk1[tAb] copptby[WB] xTrif(mnr)"delC"[tAb] is detectable
    *** cells: HEK293<xTrif(mnr)"delC"><xTbk1> in BMS
    *** source: 14530355-Fig-4c
  *** xTbk1[tAb] copptby[WB] xTrif(mnr)"delC"[tAb] is detectable
    *** cells: HEK293<xTrif(mnr)"delC"><xTbk1> in BMS
    *** unaffected by: xTrif(E88A/E252A/E303A/mnr)"delC" [substitution]
    *** source: 14530355-Fig-6
  *** xTbk1[tAb] copptby[WB] xTrif[tAb] is detectable
    *** cells: HEK293T<xTLR3> in BMS
    *** source: 12692549-Fig-6c
  *** xTbk1[tAb]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: HEK293 in BMS
    *** source: 12559944-Fig-4a
  *** xTbk1[tAb]IP IVKA(Ikba)[32P-ATP] is detectable
    *** cells: HEK293 in BMS
    *** source: 12559944-Fig-4a,4c
  *** Tbp-gene mRNA[RTPCR] is decreased itao Jnk1 [RNAi]
    *** cells: HUH7 in BMS
    *** source: 17074809-Fig-2a
  *** Tbp-gene mRNA[RTPCR] is increased itao Jnk2 [RNAi]
    *** cells: HUH7 in BMS
    *** source: 17074809-Fig-2a
  *** Tbp-gene promo-reporter[Luc] is increased itao Jnk2 [RNAi]
    *** cells: HUH7 in BMS
    *** source: 17074809-Fig-3a
  *** Tbp[Ab] prot-exp[WB] is decreased itao Elk1 [RNAi]
    *** cells: HUH7 in BMS
    *** source: 17074809-Fig-3b
  *** Tbp[Ab] prot-exp[WB] is decreased itao Jnk1 [KO]
    *** cells: mEFs in BMS
    *** source: 17074809-Fig-1b
  *** Tbp[Ab] prot-exp[WB] is decreased itao Jnk1 [KO]
    *** cells: mEFs in BMS
    *** source: 17074809-Fig-5a
  *** Tbp[Ab] prot-exp[WB] is decreased itao Jnk1 [RNAi]
    *** cells: HUH7 in BMS
    *** source: 17074809-Fig-2b
  *** Tbp[Ab] prot-exp[WB] is increased itao Jnk2 [KO]
    *** cells: mEFs in BMS
    *** source: 17074809-Fig-1b
  *** Tbp[Ab] prot-exp[WB] is increased itao Jnk2 [KO]
    *** cells: mEFs in BMS
    *** source: 17074809-Fig-5a
  *** Tbp[Ab] prot-exp[WB] is increased itao Jnk2 [RNAi]
    *** cells: HUH7 in BMS
    *** source: 17074809-Fig-2b
  *** Tbp[Ab] snaggedby[WB] rElk1(307-428){phos}[Gal4-DBD-G5TATA] is detectable
    *** cells: mESCs in BMS "nuclear extracts"
    *** does not req: Med23 [KO]
    *** source: 14506297-Fig-3
  *** Tbp[Ab] snaggedby[WB] rElk1(307-428){phos}[Gal4-DBD-G5TATA] is detectable
    *** cells: mESCs in BMS "nuclear extracts"
    *** unaffected by: rElk1(307-428) [substitution]
    *** source: 14506297-Fig-3
*** TCF--
  *** TCF-reporter[Luc] is decreased itao Tnik [RNAi]
    *** cells: DLD1 in BMS
    *** source: 20530691-Fig-4a
  *** TCF-reporter[Luc] is decreased itao Tnik [RNAi]
    *** cells: HCT116 in BMS
    *** source: 20530691-Fig-4a
  *** TCF-reporter[Luc] is decreased itao Tnik [RNAi]
    *** cells: HCT116 in BMS
    *** source: 21710659-Fig-1b
  *** TCF-reporter[Luc] is decreased itao Tnik [RNAi]
    *** cells: LS174T in BMS
    *** source: 19816403-Fig-4a
  *** TCF-reporter[Luc] is decreased itao Tnik [RNAi]
    *** cells: SW480 in BMS
    *** source: 19816403-Fig-S2a
  *** TCF-reporter[Luc] is decreased itao Tnik [RNAi]
    *** cells: SW480 in BMS
    *** source: 21710659-Fig-1b
  *** TCF-reporter[Luc] is decreased itpo xApc
    *** cells: SW480 in BMS
    *** source: 9065401-Fig-3b
  *** TCF-reporter[Luc] is decreased itpo xPtk6
    *** cells: HEK293<xCtnnb1(Y64F)> in BMS
    *** enhanced by: xPtk6(Y447F)"CA" [substitution]
    *** unaffected by: xPtk6(K219M)"KD" [substitution]
    *** source: 20016641-Fig-4b
  *** TCF-reporter[Luc] is decreased itpo xPtk6
    *** cells: HEK293<xCtnnb1(Y124F)> in BMS
    *** unaffected by: xCtnnb1(Y64F/Y142F) [substitution]
    *** unaffected by: xCtnnb1(Y64F/Y142F/Y331F/Y333F) [substitution]
    *** source: 20016641-Fig-4c
  *** TCF-reporter[Luc] is decreased itpo xPtk6
    *** cells: HEK293<xCtnnb1> in BMS
    *** enhanced by: xPtk6(Y447F)"CA" [substitution]
    *** unaffected by: xPtk6(K219M)"KD" [substitution]
    *** source: 20016641-Fig-2b
  *** TCF-reporter[Luc] is decreased itpo xPtk6(NLS)
    *** cells: SW620 in BMS
    *** enhanced by: xPtk6(NLS/Y447F) [substitution]
    *** reversed by: xPtk6(NLS/K216M) [substitution]
    *** source: 20016641-Fig-5a
  *** TCF-reporter[Luc] is decreased itpo xTab2
    *** cells: HEK293T<xWnt1> in BMS
    *** inhibited by: xTab2(178-693)"C1" [substitution]
    *** inhibited by: xTab2(292-693)"C2" [substitution]
    *** unaffected by: xTab2(417-693)"C3" [substitution]
    *** unaffected by: xTab2(477-693)"C4" [substitution]
    *** source: 20194509-Fig-4e
  *** TCF-reporter[Luc] is decreased itpo xTab2
    *** cells: HEK293T<xWnt1> in BMS
    *** partially reversed by: xTab2(del(292-417))"delM" [substitution]
    *** source: 20194509-Fig-4e
  *** TCF-reporter[Luc] is decreased itpo xTab2
    *** cells: HEK293T<xWnt1> in BMS
    *** reqs: Nlk [RNAi]
    *** source: 20194509-Fig-4d
  *** TCF-reporter[Luc] is decreased itpo xTab2
    *** cells: HEK293T<xWnt1> in BMS
    *** reversed by: xTak1(mnr)"KD" [addition]
    *** reversed by: xNlk(mnr)"KD" [addition]
    *** source: 20194509-Fig-4c
  *** TCF-reporter[Luc] is decreased itpo xTcf7l2(mnr)"DN"
    *** cells: DLD1 in BMS
    *** source: 20530691-Fig-4a
  *** TCF-reporter[Luc] is decreased itpo xTcf7l2(mnr)"DN"
    *** cells: HCT116 in BMS
    *** source: 20530691-Fig-4a
  *** TCF-reporter[Luc] is decreased itpo xTfap2a
    *** cells: HCT116 in BMS
    *** source: 15331612-Fig-2
  *** TCF-reporter[Luc] is decreased itpo xTfap2a
    *** cells: HEK293 in BMS
    *** source: 15331612-Fig-2
  *** TCF-reporter[Luc] is decreased itpo xTfap2a
    *** cells: HT29 in BMS
    *** source: 15331612-Fig-2
  *** TCF-reporter[Luc] is detectable
    *** cells: DLD1 in BMS
    *** enhanced by: xTnik [addition]
    *** inhibited by: xTnik(R152A/D153A) [addition]
    *** inhibited by: xTnik(K54A) [addition]
    *** inhibited by: xTnik(D171A/F172A) [addition]
    *** source: 19816403-Fig-S2b
  *** TCF-reporter[Luc] is detectable
    *** cells: DLD1 in BMS
    *** partially reqs: Mekk1 [RNAi]
    *** source: 20128690-Fig-3d
  *** TCF-reporter[Luc] is detectable
    *** cells: LS174T in BMS
    *** enhanced by: xTnik [addition]
    *** inhibited by: xTnik(R152A/D153A) [addition]
    *** inhibited by: xTnik(K54A) [addition]
    *** inhibited by: xTnik(D171A/F172A) [addition]
    *** source: 19816403-Fig-4c
  *** TCF-reporter[Luc] is detectable
    *** cells: MCF10A in BMLS "treated with Egf (9 hr)"
    *** partially inhibited by: xTcf7l2(31-619)"DN" [addition]
    *** source: 15026412-Fig-2b
  *** TCF-reporter[Luc] is detectable
    *** cells: SW480 in BMS
    *** partially inhibited by: xTcf7l2(31-619)"DN" [addition]
    *** source: 15026412-Fig-2a
  *** TCF-reporter[Luc] is increased itao Ptk6 [RNAi]
    *** cells: SW620 in BMS
    *** source: 20016641-Fig-6
  *** TCF-reporter[Luc] is increased itao Tab2 [RNAi]
    *** cells: HEK293T in BMS
    *** source: 20194509-Fig-3c
  *** TCF-reporter[Luc] is increased itpo (xCtnnb1 + xTcf7l2)
    *** cells: PC3U in BMS
    *** enhanced by: xSmad7 [addition]
    *** source: 15684397-Fig-S3
  *** TCF-reporter[Luc] is increased itpo (xCtnnb1 + xYwhaz)
    *** cells: CHO in BMS
    *** reqs: both [omissions]
    *** source: 15492215-Fig-2a
  *** TCF-reporter[Luc] is increased itpo (xCtnnb1 + xYwhaz)
    *** cells: DLD1 in BMS
    *** reqs: both [omissions]
    *** source: 15492215-Fig-2c
  *** TCF-reporter[Luc] is increased itpo (xDvl1 + xCsnk1e)
    *** cells: HEK293<xTcf7l2> in BMS
    *** reqs: xDvl1 [omission]
    *** source: 11425858-Fig-9a
  *** TCF-reporter[Luc] is increased itpo (xDvl1 + xFrat1 + xCsnk1e)
    *** cells: HEK293<xTcf7l2> in BMS
    *** partially inhibited by: xCsnk1(mnr)"KD" [substitution]
    *** partially inhibited by: xFrat1(1-185) [substitution]
    *** source: 12556519-Fig-7a
  *** TCF-reporter[Luc] is increased itpo (xDvl1 + xFrat1 + xWnt3a)
    *** cells: HEK293<xTcf7l2> in BMS
    *** partially inhibited by: xFrat1(1-185) [substitution]
    *** source: 12556519-Fig-7b
  *** TCF-reporter[Luc] is increased itpo (xFzd9 + xWnt2)
    *** cells: HEK293T in BMS
    *** inhibited by: xFzd9(del(58-174))"N" [substitution]
    *** source: 12138115-Fig-6c
  *** TCF-reporter[Luc] is increased itpo (xFzd9 + xWnt2)
    *** cells: HEK293T in BMS
    *** unaffected by: xFzd9(1-587)"C5" [substitution]
    *** partially inhibited by: xFzd9(1-577)"C15" [substitution]
    *** partially inhibited by: xFzd9(1-566)"C26" [substitution]
    *** partially inhibited by: xFzd9(1-554)"C38" [substitution]
    *** source: 12138115-Fig-5b
  *** TCF-reporter[Luc] is increased itpo (xPias4 + xCtnnb1(mnr)"non-degradable")
    *** cells: HELA<xTcf7l2(del(128-150))> in BMS
    *** inhibited by: xTcf7l2(del(128-150)/K320R) [substitution]
    *** source: 12727872-Fig-7f
  *** TCF-reporter[Luc] is increased itpo (xPias4 + xCtnnb1(mnr)"non-degradable")
    *** cells: HELA<xTcf7l2(del(128-150))> in BMS
    *** inhibited by: xTcf7l2(K320R) [substitution]
    *** source: 12727872-Fig-7e
  *** TCF-reporter[Luc] is increased itpo (xTcf7l2 + xCtnnb1)
    *** cells: IIA16 in BMS
    *** reqs: both [omission]
    *** inhibited by: xTcf7l2(31-619) [substitution]
    *** source: 9065401-Fig-3a
  *** TCF-reporter[Luc] is increased itpo xCsnk1e
    *** cells: HEK293<xDvl3> in BMS
    *** inhibited by: xDvl3(mnr)"CT" [substitution]
    *** enhanced by: xDvl3(mnr)"delC" [substitution]
    *** source: 20215527-Fig-5a
  *** TCF-reporter[Luc] is increased itpo xCsnk1e
    *** cells: HEK293<xDvl3> in BMS
    *** inhibited by: xDvl3(mnr)"CT" [substitution]
    *** source: 20215527-Fig-5b
  *** TCF-reporter[Luc] is increased itpo xCsnk1e
    *** cells: HEK293<xDvl3> in BMS
    *** inhibited by: xRor2 [addition]
    *** partially inhibited by: xRor2(mnr)"del745" [addition]
    *** inhibited by: xRor2(mnr)"13ST" [addition]
    *** inhibited by: xRor2(mnr)"5YF" [addition]
    *** source: 20215527-Fig-4a
  *** TCF-reporter[Luc] is increased itpo xCsnk1e
    *** cells: HEK293<xDvl3> in BMS
    *** repressed by: Ror2 [RNAi]
    *** source: 20215527-Fig-5c
  *** TCF-reporter[Luc] is increased itpo xCsnk1e
    *** cells: HEK293<xTcf7l2><xDvl1> in BMS
    *** inhibited by: xDvl1(1-432) [substitution]
    *** unaffected by: xDvl1(1-519) [substitution]
    *** inhibited by: xDvl1(del(282-336))"delPDZ" [substitution]
    *** inhibited by: xDvl1(140-670) [substitution]
    *** source: 11425858-Fig-9b
  *** TCF-reporter[Luc] is increased itpo xCsnk1e
    *** cells: HEK293<xTcf7l2><xDvl1> in BMS
    *** inhibited by: xDvl1(del(228-250)) [substitution]
    *** source: 12556519-Fig-5c
  *** TCF-reporter[Luc] is increased itpo xCtnnb1
    *** cells: HEK293 in BMS
    *** enhanced by: xCtnnb1(S33Y) [substitution]
    *** enhanced by: xCtnnb1(K19R/K49R) [substitution]
    *** enhanced by: xCtnnb1(K19R) [substitution]
    *** unaffected by: xCtnnb1(K49R) [substitution]
    *** source: 16849322-Fig-3
  *** TCF-reporter[Luc] is increased itpo xCtnnb1
    *** cells: HEK293 in BMS
    *** inhibited by: xDvl3(mnr)"CT" [addition]
    *** source: 20215527-Fig-5e
  *** TCF-reporter[Luc] is increased itpo xCtnnb1
    *** cells: HEK293 in BMS
    *** inhibited by: xRor2 [addition]
    *** partially inhibited by: xRor2(mnr)"del745" [addition]
    *** inhibited by: xRor2(mnr)"13ST" [addition]
    *** inhibited by: xRor2(mnr)"5YF" [addition]
    *** source: 20215527-Fig-4b
  *** TCF-reporter[Luc] is increased itpo xCtnnb1
    *** cells: HEK293 in BMS
    *** inhibited by: xTfap2a [addition]
    *** source: 15331612-Fig-1a
  *** TCF-reporter[Luc] is increased itpo xCtnnb1
    *** cells: HEK293 in BMS
    *** repressed by: Ror2 [RNAi]
    *** source: 20215527-Fig-5e
  *** TCF-reporter[Luc] is increased itpo xCtnnb1
    *** cells: HEK293T in BMS
    *** enhanced by: xYwhaz [addition]
    *** source: 15492215-Fig-2b
  *** TCF-reporter[Luc] is increased itpo xCtnnb1
    *** cells: HELA in BMS
    *** source: 11533658-Fig-2a
  *** TCF-reporter[Luc] is increased itpo xCtnnb1(mnr)"del45"
    *** cells: HEK293 in BMS
    *** inhibited by: xTfap2a [addition]
    *** source: 15331612-Fig-1c
  *** TCF-reporter[Luc] is increased itpo xCtnnb1(mnr)"delN"
    *** cells: HEK293T in BMS
    *** inhibited by: xTab2 [addition]
    *** inhibited by: xTab2 + xIkk2(mnr)"KD" [addition]
    *** source: 20194509-Fig-4b
  *** TCF-reporter[Luc] is increased itpo xCtnnb1(mnr)"delN"
    *** cells: HEK293T in BMS
    *** partially inhibited by: xTab2 [addition]
    *** source: 20194509-Fig-3a
  *** TCF-reporter[Luc] is increased itpo xCtnnb1(mnr)"delN134"
    *** cells: HELA in BMS
    *** enhanced by: xTnik [addition]
    *** source: 20530691-Fig-S6a
  *** TCF-reporter[Luc] is increased itpo xCtnnb1(mnr)"delN134"
    *** cells: HELA in BMS
    *** inhibited by: xTcf7l2(mnr)"DN" [addition]
    *** source: 20530691-Fig-S6b
  *** TCF-reporter[Luc] is increased itpo xCtnnb1(mnr)"delN134"
    *** cells: HELA in BMS
    *** reqs: Tnik [RNAi]
    *** source: 20530691-Fig-S6b
  *** TCF-reporter[Luc] is increased itpo xCtnnb1(mnr)"non-degradable"
    *** cells: HEK293<xLef1> in BMS
    *** enhanced by: xPias4 [addition]
    *** inhibited by: xPias4(C342A/C347A) [substitution]
    *** source: 12727872-Fig-7c
  *** TCF-reporter[Luc] is increased itpo xCtnnb1(mnr)"non-degradable"
    *** cells: HEK293<xTcf7l2(del(128-150))> in BMS
    *** enhanced by: xPias4 [addition]
    *** inhibited by: xPias4(C342A/C347A) [substitution]
    *** source: 12727872-Fig-7b
  *** TCF-reporter[Luc] is increased itpo xCtnnb1(mnr)"non-degradable"
    *** cells: HEK293<xTcf7l2(del(128-150))> in BMS
    *** enhanced by: xPias4 [addition]
    *** inhibited by: xTcf7l2(del(1-54)/del(128-150)) [substitution]
    *** source: 12727872-Fig-7d
  *** TCF-reporter[Luc] is increased itpo xCtnnb1(mnr)"non-degradable"
    *** cells: HEK293<xTcf7l2(del(128-150))> in BMS
    *** enhanced by: xPias4 [addition]
    *** source: 12727872-Fig-7a
  *** TCF-reporter[Luc] is increased itpo xCtnnb1(mnr)"non-degradable"
    *** cells: HEK293<xTcf7l2(del(128-150))> in BMS
    *** inhibited by: xSenp2 [addition]
    *** source: 12727872-Fig-8a
  *** TCF-reporter[Luc] is increased itpo xCtnnb1(mnr)"non-degradable"
    *** cells: HELA<xTcf7l2(del(128-150))> in BMS
    *** repressed by: Senp2 [RNAi]
    *** source: 12727872-Fig-8b
  *** TCF-reporter[Luc] is increased itpo xCtnnb1(mnr)"non-degradable"
    *** cells: HELA<xTcf7l2(del(128-150))> in BMS
    *** unaffected by: xTcf7l2(del(128-150)/K320R) [substitution]
    *** enhanced by: xPias4 [addition]
    *** source: 12727872-Fig-7f
  *** TCF-reporter[Luc] is increased itpo xCtnnb1(S33Y)
    *** cells: HEK293 in BMS
    *** inhibited by: xTfap2a [addition]
    *** source: 15331612-Fig-1b
  *** TCF-reporter[Luc] is increased itpo xDvl?
    *** cells: HEK293 in BMS
    *** inhibited by: xAdrbk?(mnr)"Cterm" [addition]
    *** source: 20460648-Fig-6a
  *** TCF-reporter[Luc] is increased itpo xDvl1
    *** cells: HEK293 in BMS
    *** enhanced by: xPias4 [addition]
    *** inhibited by: xPias4(C342A/C347A) [substitution]
    *** source: 12727872-Fig-7g
  *** TCF-reporter[Luc] is increased itpo xDvl1
    *** cells: HEK293<xTcf7l2> in BMS
    *** enhanced by: xCsnk1e [addition]
    *** source: 11425858-Fig-9a
  *** TCF-reporter[Luc] is increased itpo xDvl1
    *** cells: HEK293<xTcf7l2> in BMS
    *** enhanced by: xCsnk1e [addition]
    *** source: 12556519-Fig-7a
  *** TCF-reporter[Luc] is increased itpo xDvl1
    *** cells: HEK293<xTcf7l2> in BMS
    *** enhanced by: xFrat1 [addition]
    *** source: 12556519-Fig-7a
  *** TCF-reporter[Luc] is increased itpo xDvl1
    *** cells: HEK293<xTcf7l2> in BMS
    *** partially inhibited by: xDvl1(1-432) [substitution]
    *** unaffected by: xDvl1(1-519) [substitution]
    *** inhibited by: xDvl1(del(282-336))"delPDZ" [substitution]
    *** inhibited by: xDvl1(140-670) [substitution]
    *** source: 11425858-Fig-9b
  *** TCF-reporter[Luc] is increased itpo xDvl1
    *** cells: HEK293<xTcf7l2> in BMS
    *** partially inhibited by: xDvl1(del(228-250)) [substitution]
    *** source: 12556519-Fig-5a
  *** TCF-reporter[Luc] is increased itpo xDvl1
    *** cells: HEK293<xTcf7l2> in BMS
    *** source: 12556519-Fig-7b
  *** TCF-reporter[Luc] is increased itpo xFrat1
    *** cells: HEK293<xTcf7l2> in BMS
    *** inhibited by: xFrat1(1-185) [substitution]
    *** source: 12556519-Fig-7b
  *** TCF-reporter[Luc] is increased itpo xFrat1
    *** cells: HEK293<xTcf7l2><xDvl1> in BMS
    *** inhibited by: xDvl1(del(228-250)) [substitution]
    *** source: 12556519-Fig-5b
  *** TCF-reporter[Luc] is increased itpo xFzd9
    *** cells: HEK293T in BMS
    *** enhanced by: xWnt2 [addition]
    *** source: 12138115-Fig-2b
  *** TCF-reporter[Luc] is increased itpo xFzd9
    *** cells: HEK293T in BMS
    *** source: 12138115-Fig-1d
  *** TCF-reporter[Luc] is increased itpo xGnb1 + xGng2 
    *** cells: HEK293<xLrp6> in BMS
    *** enhanced by: xGnb1(T47A) [substitution]
    *** enhanced by: xGnb1(L55A) [substitution]
    *** inhibited by: xGnb1(K57A) [substitution]
    *** inhibited by: xGnb1(Y59A) [substitution]
    *** inhibited by: xGnb1(K78A) [substitution]
    *** enhanced by: xGnb1(I80A) [substitution]
    *** enhanced by: xGnb1(K89A) [substitution]
    *** inhibited by: xGnb1(W99A) [substitution]
    *** unaffected by: xGnb1(M101A) [substitution]
    *** unaffected by: xGnb1(L117A) [substitution]
    *** inhibited by: xGnb1(T143A) [substitution]
    *** inhibited by: xGnb1(Y145A) [substitution]
    *** inhibited by: xGnb1(D186A) [substitution]
    *** inhibited by: xGnb1(M188A) [substitution]
    *** inhibited by: xGnb1(N230A) [substitution]
    *** inhibited by: xGnb1(W322A) [substitution]
    *** source: 20460648-Fig-5a
  *** TCF-reporter[Luc] is increased itpo xIkba(S32A/S36A)
    *** cells: HEK293T in BMS
    *** unaffected by: xTab2 [addition]
    *** source: 20194509-Fig-4a
  *** TCF-reporter[Luc] is increased itpo xLef1
    *** cells: HELA in BMS "treated with Wnt1 for 24 hr"
    *** enhanced by: xLef1(T155A/S166A) [substitution]
    *** source: 12556497-Fig-6
  *** TCF-reporter[Luc] is increased itpo xLef1
    *** cells: HELA in BMS "treated with Wnt1 for 24 hr"
    *** inhibited by: xNlk [addition]
    *** unaffected by: xNlk(K155M) [addition]
    *** source: 12556497-Fig-6
  *** TCF-reporter[Luc] is increased itpo xLrp6
    *** cells: HEK293 in BMS
    *** enhanced by: xGnb1 + xGng2 [addition]
    *** inhibited by: xAdrbk?(mnr)"Cterm" [addition]
    *** source: 20460648-Fig-3a
  *** TCF-reporter[Luc] is increased itpo xLrp6
    *** cells: HEK293 in BMS
    *** enhanced by: xGnb1 + xGng2 [addition]
    *** unaffected by: xGnb1 + xGng2(mnr)"CAAX" [addition]
    *** source: 20460648-Fig-3c
  *** TCF-reporter[Luc] is increased itpo xLrp6
    *** cells: HEK293 in BMS
    *** inhibited by: xAdrbk?(mnr)"Cterm" [addition]
    *** source: 20460648-Fig-3b
  *** TCF-reporter[Luc] is increased itpo xLrp6
    *** cells: HEK293 in BMS
    *** inhibited by: xDvl?(mnr)"DN" [addition]
    *** source: 20460648-Fig-6b
  *** TCF-reporter[Luc] is increased itpo xLrp6
    *** cells: HEK293<xGnb1><xGng2> in BMS
    *** inhibited by: xDvl?(mnr)"DN" [addition]
    *** source: 20460648-Fig-6b
  *** TCF-reporter[Luc] is increased itpo xLrp6
    *** cells: HEK293T in BMS
    *** enhanced by: xLrp6(mnr)"delNterm" [substitution]
    *** source: 12897152-Fig-1c
  *** TCF-reporter[Luc] is increased itpo xLrp6
    *** cells: HEK293T<xWnt3a> in BMS
    *** unaffected by: xLrp6(mnr)"delNterm" [substitution]
    *** source: 12897152-Fig-1c
  *** TCF-reporter[Luc] is increased itpo xPias4
    *** cells: HEK293<xTcf7l2(del(128-150))> in BMS
    *** enhanced by: xCtnnb1(mnr)"non-degradable" [addition]
    *** source: 12727872-Fig-7a
  *** TCF-reporter[Luc] is increased itpo xPias4
    *** cells: HELA<xTcf7l2(del(128-150))> in BMS
    *** enhanced by: xCtnnb1(mnr)"non-degradable" [addition]
    *** source: 12727872-Fig-7e
  *** TCF-reporter[Luc] is increased itpo xPias4
    *** cells: HELA<xTcf7l2(del(128-150))> in BMS
    *** enhanced by: xCtnnb1(mnr)"non-degradable" [addition]
    *** unaffected by: xTcf7l2(del(128-150)/K320R) [substitution]
    *** source: 12727872-Fig-7e
  *** TCF-reporter[Luc] is increased itpo xPin1
    *** cells: HELA in BMS
    *** inhibited by: xPin1(W34A) [substitution]
    *** inhibited by: xPin1(K63A) [substitution]
    *** inhibited by: xPin1(R68A/R69A) [substitution]
    *** source: 11533658-Fig-2b
  *** TCF-reporter[Luc] is increased itpo xPin1
    *** cells: HELA in BMS
    *** inhibited by: xTcf7l2(mnr)"DN" [addition]
    *** source: 11533658-Fig-2c
  *** TCF-reporter[Luc] is increased itpo xPin1
    *** cells: HELA in BMS
    *** source: 11533658-Fig-2a
  *** TCF-reporter[Luc] is increased itpo xPpp2r2a
    *** cells: HEK293T<xWnt3a> in BMS
    *** inhibited by: xPpp2r2a(mnr)"del1" [substitution]
    *** inhibited by: xPpp2r2a(mnr)"del2" [substitution]
    *** inhibited by: xPpp2r2a(mnr)"del3" [substitution]
    *** source: 19556239-Fig-5d
  *** TCF-reporter[Luc] is increased itpo xPtk6(myr)
    *** cells: SW620 in BMS
    *** enhanced by: xPtk6(myr/Y447F) [substitution]
    *** inhibited by: xPtk6(myr/K216M) [substitution]
    *** source: 20016641-Fig-5a
  *** TCF-reporter[Luc] is increased itpo xTnik
    *** cells: DLD1 in BMS
    *** inhibited by: xTnik(K54R)"KD" [substitution]
    *** source: 20530691-Fig-S7a
  *** TCF-reporter[Luc] is increased itpo xTnik
    *** cells: DLD1<xTcf7l2> in BMS
    *** inhibited by: xTnik(K54R)"KD" [substitution]
    *** inhibited by: xTcf7l2(S154A) [substitution]
    *** source: 20530691-Fig-S7b
  *** TCF-reporter[Luc] is increased itpo xTnik
    *** cells: HCT116 in BMS
    *** inhibited by: xTnik(K54R)"KD" [substitution]
    *** source: 20530691-Fig-S7a
  *** TCF-reporter[Luc] is increased itpo xYwhaz
    *** cells: HEK293T<xCtnnb1><xAkt1(mnr)"CA"> in BMS
    *** partially inhibited by: xAkt1(mnr)"KD" [substitution]
    *** source: 15492215-Fig-3c
  *** TCF-reporter[Luc] is unchanged itao Tnik [RNAi]
    *** cells: HEK293T in BMS
    *** source: 19816403-Fig-4b
  *** TCF-reporter[Luc] is unchanged itpo xDvl3
    *** cells: HEK293 in BMS
    *** source: 20215527-Fig-4a
  *** TCF-reporter[Luc] is unchanged itpo xFzd1
    *** cells: HEK293T in BMS
    *** source: 10557084-Fig-2a
  *** TCF-reporter[Luc] is unchanged itpo xGnb1 + xGng2
    *** cells: HEK293 in BMS
    *** unaffected by: xGng2(mnr)"CAAX" [substitution]
    *** source: 20460648-Fig-3c
  *** TCF-reporter[Luc] is unchanged itpo xLef1
    *** cells: HELA in BMS
    *** source: 12556497-Fig-6
  *** TCF-reporter[Luc] is unchanged itpo xNlk
    *** cells: HELA in BMS "treated with Wnt1 for 24 hr"
    *** source: 12556497-Fig-6
  *** TCF-reporter[Luc] is unchanged itpo xYwhaz
    *** cells: HEK293T in BMS
    *** source: 15492215-Fig-2b
  *** rTcf3[35S] boundby[WB] rId2[GST] is detectable
    *** cells: none
    *** source: 10022839-Fig-3c
  *** Tcf7-gene mRNA[RTPCR] is detectable
    *** cells: DLD1 in BMS
    *** partially reqs: Mekk1 [RNAi]
    *** source: 20128690-Fig-4b
  *** xTcf7l2(del(128-150))[Ab] oligo-binding[EMSA] is unchanged itpo xPias4
    *** cells: HEK293<xSumo1> in BMS "nuclear-extracts"
    *** oligo: oligo-name-not-reported sequence-not-reported
    *** unaffected by: rPias4(C342A/C347A) [substitution]
    *** source: 12727872-Fig-5a
  *** xTcf7l2(del(128-150))[Ab] oligo-binding[EMSA] is unchanged itpo xSumo1
    *** cells: HEK293 in BMS "nuclear-extracts"
    *** oligo: oligo-name-not-reported sequence-not-reported
    *** source: 12727872-Fig-5a
  *** xTcf7l2(del(128-150))[Ab] snaggedby[WB] Ctnnb1(132-536)[GST] is detectable
    *** cells: HEK293 in BMS "nuclear-extracts"
    *** comment: coexpression of Sumo1 and Pias4 causes ppt Tcf7l2 to be sumoylated
    *** source: 12727872-Fig-4b
  *** xTcf7l2(del(128-150))[Ab]IP sumo[tSuAb] is decreased by rSenp2
    *** cells: none
    *** IPfrom: HEK293<xSumo1><xPias4> in BMS
    *** source: 12727872-Fig-3f
  *** xTcf7l2(del(128-150))[Ab]IP sumo[tSuAb] is detectable
    *** cells: HEK293<xSumo1> in BMS
    *** inhibited by: xSumo1(1-95) [substitution]
    *** source: 12727872-Fig-2b
  *** xTcf7l2(del(128-150))[Ab]IP upshift[WBMS] is decreased itpo xSenp2
    *** cells: HEK293<xSumo1><xPias4> in BMS
    *** reversed by: xSenp2(C547S)"CIA" [substitution]
    *** source: 12727872-Fig-3e
  *** xTcf7l2(del(128-150))[Ab]IP upshift[WBMS] is detectable
    *** cells: HEK293<xSumo1> in BMS
    *** inhibited by: xTcf7l2(del(128-150)/K320R) [substitution]
    *** inhibited by: xTcf7l2(del(128-150)/K22R/K320R/K340R/K341R/K430R/K539R) [substitution]
    *** inhibited by: xTcf7l2(E322A) [substitution]
    *** source: 12727872-Fig-2c
  *** xTcf7l2(del(128-150))[Ab]IP upshift[WBMS] is increased itpo xPias4
    *** cells: HEK293<xSumo1> in BMS
    *** partially inhibited by: xPias4(C342A/C347A) [addition]
    *** source: 12727872-Fig-3b
  *** xTcf7l2(del(128-150))[Gal4-DBD] Gal4-reporter[Luc] is increased itpo xPias4
    *** cells: HEK293 in BMS
    *** inhibited by: xTcf7l2(del(128-150)/del(297-410)) [substitution]
    *** unaffected by: xTcf7l2(1-339) [substitution]
    *** unaffected by: xTcf7l2(80-339) [substitution]
    *** inhibited by: xTcf7l2(339-619) [substitution]
    *** source: 12727872-Fig-8d
  *** Tcf7l2[Ab] boundto(Axin2-gene)[ChIP] is unchanged itao Ctnnb1 [RNAi]
    *** cells: LS174T in BMS
    *** source: 19816403-Fig-3c
  *** Tcf7l2[Ab] boundto(Fosl1-gene)[ChIP] is undetectable
    *** cells: HCT116 in BMS "treated with Anisomycin"
    *** source: 16007074-Fig-2b
  *** Tcf7l2[Ab] boundto(Myc-gene)[ChIP] is detectable
    *** cells: HCT116 in BMS "treated with Anisomycin"
    *** source: 16007074-Fig-2b
  *** Tcf7l2[Ab] boundto(Myc-gene)[ChIP] is unchanged itao Ctnnb1 [RNAi]
    *** cells: LS174T in BMS
    *** source: 19816403-Fig-3c
  *** Tcf7l2[Ab] boundto(Srf-gene)[ChIP] is undetectable
    *** cells: HCT116 in BMS "treated with Anisomycin"
    *** source: 16007074-Fig-2b
  *** Tcf7l2[Ab] copptby[WB] Tfap2a[Ab] is undetectable
    *** cells: HCT116 in BMS
    *** source: 15331612-Fig-4a
  *** Tcf7l2[Ab] copptby[WB] Tfap2a[Ab] is undetectable
    *** cells: HEK293 in BMS
    *** source: 15331612-Fig-4a
  *** Tcf7l2[Ab] copptby[WB] Tfap2a[Ab] is undetectable
    *** cells: HT29 in BMS
    *** source: 15331612-Fig-4a
  *** Tcf7l2[Ab] copptby[WB] Tnik[Ab] is decreased itao Ctnnb1 [RNAi]
    *** cells: LS174T in BMS
    *** source: 19816403-Fig-3b
  *** xTcf7l2[Ab] copptby[WB] xCtnnb1[Ab] is detectable
    *** cells: HEK293<xCtnnb1><xTcf7l2> in BMS
    *** unaffected by: xNlk [addition]
    *** comment: Tcf7l2 band upshifts when xNlk is added
    *** source: 10391247-Fig-5a
  *** xTcf7l2[Ab] copptby[WB] xNlk[tAb] is detectable
    *** cells: HEK293<xTcf7l2><xNlk> in BMS
    *** unaffected by: xNlk(K155M) [substitution]
    *** comment: Tcf7l2 band downshifts when xNlk(K155M) is substituted
    *** inhibited by: xNlk(C425Y) [substitution]
    *** source: 10391247-Fig-4a
  *** xTcf7l2[Ab] copptby[WB] xSmad7(204-426)"Cterm"[tAb] is detectable
    *** cells: HEK293T in BMS
    *** partially inhibited by: xSmad7(WT) [substitution]
    *** source: 15684397-Fig-1b
  *** Tcf7l2[Ab] infraction(nuclear)[WB] is unchanged itpo xTfap2a
    *** cells: HCT116 in BMS
    *** source: 15331612-Fig-3
  *** Tcf7l2[Ab] infraction(nuclear)[WB] is unchanged itpo xTfap2a
    *** cells: HEK293 in BMS
    *** source: 15331612-Fig-3
  *** Tcf7l2[Ab] infraction(nuclear)[WB] is unchanged itpo xTfap2a
    *** cells: HT29 in BMS
    *** source: 15331612-Fig-3
  *** Tcf7l2[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: DLD1<xTnik> in BMS
    *** source: 20530691-Fig-S4a
  *** Tcf7l2[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: DLD1<xTnik> in BMS
    *** unaffected by: xTnik(K54R)"KD" [substitution]
    *** source: 20530691-Fig-S4a
  *** xTcf7l2[Ab] oligo-binding[EMSA] is detectable
    *** cells: HEK293<xCtnnb1><xTcf7l2> in BMS
    *** unaffected by: xNlk [addition]
    *** source: 10391247-Fig-5b
  *** xTcf7l2[Ab] oligo-binding[EMSA] is detectable
    *** cells: HEK293<xCtnnb1><xTcf7l2> in BMS "nuclear-extracts"
    *** inhibited by: xNlk [addition]
    *** unaffected by: xNlk(K155M) [addition]
    *** source: 12556497-Fig-7b
  *** xTcf7l2[Ab] oligo-binding[EMSA] is detectable
    *** cells: HEK293<xCtnnb1><xTcf7l2> in BMS "nuclear-extracts"
    *** unaffected by: xTcf7l2(T178V/T189V) [substitution]
    *** source: 12556497-Fig-7b
  *** xTcf7l2[Ab] phos[WBMS-PPase] is increased itpo xNlk
    *** cells: HEK293<xTcf7l2> in BMS
    *** enhanced by: xTak1 + xTab1 [addition]
    *** source: 10391247-Fig-4b
  *** xTcf7l2[Ab] phos[WBMS-PPase] is increased itpo xNlk
    *** cells: HEK293<xTcf7l2> in BMS
    *** inhibited by: xNlk(K155M) [substitution]
    *** source: 10391247-Fig-4b
  *** rTcf7l2[Ab] upshift[WBMS] is detectable
    *** cells: none
    *** comment: reaction also contains rSae1, rUba2 and rUbe2i
    *** reqs: rUbe2i [omission]
    *** source: 12727872-Fig-3c
  *** rTcf7l2[Ab] upshift[WBMS] is detectable
    *** cells: none
    *** comment: reaction also contains rSumo1(1-97), rSae1, rUba2 and rUbe2i
    *** reqs: rUbe2i [omission]
    *** source: 12727872-Fig-3c
  *** rTcf7l2[Ab] upshift[WBMS] is detectable
    *** cells: none
    *** comment: reaction also contains rSumo1(1-97), rSae1, rUba2, rUbe2i, and rPias4
    *** reqs: rSumo1(1-97) [omission]
    *** inhibited by: rSumo1(1-95) [substitution]
    *** reqs: rSae1 and/or rUba2 [omission]
    *** reqs: rUbe2i [omission]
    *** reqs: rPias4 [omission]
    *** inhibited by: rPias4(C342A/C347A) [substitution]
    *** source: 12727872-Fig-3d
  *** Tcf7l2[Ab]IP sumo[SuAb] is increased itao Senp2 [RNAi]
    *** cells: HEK293 in BMS "nuclear-extracts"
    *** comment: Tcf7l2 was ppt with rCtnnb1(1-576)[His]
    *** source: 12727872-Fig-4b
  *** Tcf7l2[Ab]IP sumo[SuAb] is increased itpo xPias4
    *** cells: HEK293 in BMS "nuclear-extracts"
    *** comment: Tcf7l2 was ppt with rCtnnb1(1-576)[His]
    *** source: 12727872-Fig-4a
  *** xTcf7l2[tAb] copptby[WB] xNlk[tAb] is detectable
    *** cells: HEK293<xTcf7l2><xNlk> in BMS
    *** unaffected by: xCtnnb1 [addition]
    *** source: 12556497-Fig-2
  *** xTcf7l2[tAb] copptby[WB] xNlk[tAb] is detectable
    *** cells: HEK293<xTcf7l2><xNlk> in BMS
    *** unaffected by: xTcf7l2(T178V/T189V) [substitution]
    *** source: 12556497-Fig-5a
  *** xTcf7l2[tAb] phos[WBMS] is increased itpo xNlk
    *** cells: HEK293<xTcf7l2> in BMS
    *** inhibited by: xNlk(K155M)"KD" [substitution]
    *** source: 12556497-Fig-4d
  *** xTcf7l2[tAb] phos[WBMS] is increased itpo xNlk
    *** cells: HEK293<xTcf7l2> in BMS
    *** partially inhibited by: xTcf7l2(T178V/T189V) [substitution]
    *** source: 12556497-Fig-4d
  *** xTec[Ab]IP Yphos[pYAb] is detectable
    *** cells: SF9 in BMS
    *** unaffected by: xStat1 [addition]
    *** source: 7657660-Fig-2c
  *** Tf[Hrp] internalization[Surface-strip] is increased itpo xRab5a
    *** cells: CHO<xTfRc> in BMLS
    *** source: 12783862-Fig-6b
  *** Tf[Hrp] internalization[Surface-strip] is increased itpo xRin1
    *** cells: CHO<xTfRc> in BMLS
    *** inhibited by: xRin1(67-154)"SH2" [substitution]
    *** source: 12783862-Fig-6b
  *** xTfdp1[Ab] locatedin(nucleus-cytoplasm)[IHC] is detectable
    *** cells: CHOC400<xTfdp1> in BMS
    *** source: 8832394-Fig-1 
  *** xTfdp1[Ab] locatedin(nucleus)[IHC] is increased itpo xE2f1
    *** cells: CHOC400<xTfdp1> in BMS
    *** partially inhibited by: xE2f1(Y411C) [substitution]
    *** inhibited by: xE2f1(1-191) [substitution]
    *** unaffected by: xE2f1(223-437) [substitution]
    *** unaffected by: xE2f1(1-416) [substitution]
    *** unaffected by: xE2f1(1-284) [substitution]
    *** unaffected by: xE2f1(1-374) [substitution]
    *** source: 8832394-Table-1b
  *** xTfdp1[Ab] locatedin(nucleus)[IHC] is increased itpo xE2f1
    *** cells: CHOC400<xTfdp1> in BMS
    *** source: 8832394-Table-1a
  *** xTfdp1[Ab] locatedin(nucleus)[IHC] is increased itpo xE2f2
    *** cells: CHOC400<xTfdp1> in BMS
    *** source: 8832394-Table-1a
  *** xTfdp1[Ab] locatedin(nucleus)[IHC] is increased itpo xE2f3
    *** cells: CHOC400<xTfdp1> in BMS
    *** source: 8832394-Table-1a
  *** xTfdp1[Ab] locatedin(nucleus)[IHC] is unchanged itpo xE2f4
    *** cells: CHOC400<xTfdp1> in BMS
    *** source: 8832394-Table-1a
  *** xTfdp1[Ab] locatedin(nucleus)[IHC] is unchanged itpo xRb1
    *** cells: CHOC400<xTfdp1> in BMS
    *** source: 8832394-Table-4
  *** xTfdp1[Ab] locatedin(nucleus)[IHC] is unchanged itpo xRbl1
    *** cells: CHOC400<xTfdp1> in BMS
    *** source: 8832394-Table-4
  *** xTfdp1[Ab] locatedin(nucleus)[IHC] is unchanged itpo xRbl2
    *** cells: CHOC400<xTfdp1> in BMS
    *** source: 8832394-Table-4
  *** xTfdp1[tAb] locatedin(nucleus)[IHC] is increased itpo xE2f1
    *** cells: CHOC400<xTfdp1> in BMS
    *** inhibited by: xTfdp1(1-204) [substitution]
    *** inhibited by: xTfdp1(1-277) [substitution]
    *** unaffected by: xTfdp1(1-346) [substitution]
    *** unaffected by: xTfdp1(102-410) [substitution]
    *** unaffected by: xTfdp1(127-410) [substitution]
    *** inhibited by: xTfdp1(182-410) [substitution]
    *** inhibited by: xTfdp1(232-410) [substitution]
    *** unaffected by: xTfdp1(del(103-126)) [substitution]
    *** inhibited by: xTfdp1(del(233-272)) [substitution]
    *** source: 8832394-Table-2
  *** xTfdp2[Ab] locatedin(nucleus-cytoplasm)[IHC] is detectable
    *** cells: CHOC400<xTfdp2> in BMS
    *** source: 8832394-Fig-1 
  *** xTfdp2[Ab] locatedin(nucleus-cytoplasm)[IHC] is increased itpo xE2f1
    *** cells: CHOC400<xTfdp2> in BMS
    *** source: 8832394-Table-1a
  *** xTfdp2[Ab] locatedin(nucleus-cytoplasm)[IHC] is increased itpo xE2f2
    *** cells: CHOC400<xTfdp2> in BMS
    *** source: 8832394-Table-1a
  *** xTfdp2[Ab] locatedin(nucleus-cytoplasm)[IHC] is increased itpo xE2f3
    *** cells: CHOC400<xTfdp2> in BMS
    *** source: 8832394-Table-1a
  *** xTfdp2[Ab] locatedin(nucleus-cytoplasm)[IHC] is increased itpo xE2f4
    *** cells: CHOC400<xTfdp2> in BMS
    *** source: 8832394-Table-1a
  *** xTfdp2[Ab] locatedin(nucleus)[IHC] is increased itpo xE2f1
    *** cells: CHOC400<xTfdp2> in BMS
    *** partially inhibited by: xE2f1(Y411C) [substitution]
    *** inhibited by: xE2f1(1-191) [substitution]
    *** unaffected by: xE2f1(223-437) [substitution]
    *** unaffected by: xE2f1(1-416) [substitution]
    *** inhibited by: xE2f1(1-284) [substitution]
    *** inhibited by: xE2f1(1-374) [substitution]
    *** source: 8832394-Table-1b
  *** rTfe3 oligo-binding[EMSA] is detectable
    *** cells: none
    *** oligo: PAI1-PE21 5-CCTAGACAGACAAAACCTAGACAATCACGTG-3
    *** comment: details of oligo sequence requirements not curated
    *** comment: rTfe3 can form a complex with rSmad3 and/or rSmad4 at this site
    *** source: 12551947-Fig-1a,1b,1c
  *** Tgfa[Ab] secretion[ELISA] is decreased itao Adam17 [RNAi]
    *** cells: MDAMB231 in BMS "treated with Cetuximab 30 min"
    *** source: 23720309-Fig-S1c
  *** Tgfa[Ab] secretion[ELISA] is increased itao Timp3 [RNAi]
    *** cells: T42 in BMS
    *** source: 22550340-Fig-6d
  *** xTgfa[AP] secretion[AP] is decreased itpo xAdam10(mnr)"DN"
    *** cells: mEFs<Adam17~null><xProTgfa> in BMS
    *** source: 19158376-Fig-2b
  *** xTgfa[AP] secretion[AP] is increased itpo xAdam10
    *** cells: mEFs<Adam17~null><Adam10~null><xProTgfa> in BMS
    *** source: 19158376-Fig-3b
  *** xTgfa[AP] secretion[AP] is unchanged itpo xAdam10
    *** cells: mEFs<Adam10~null><xProTgfa> in BMS
    *** source: 19158376-Fig-2g
  *** xTgfa[AP] secretion[AP] is unchanged itpo xAdam10(mnr)"DN"
    *** cells: mEFs<Adam10~null><xProTgfa> in BMS
    *** source: 19158376-Fig-2c
  *** xTgfa[AP] secretion[AP] is unchanged itpo xAdam10(mnr)"DN"
    *** cells: mEFs<xProTgfa> in BMS
    *** source: 19158376-Fig-2a
  *** Tgfb1-gene mRNA[RTPCR] is detectable
    *** cells: mEFs in BMS
    *** reqs: Egr1 [KO]
    *** source: 15958557-Fig-1
  *** Tgfb1-gene mRNA[RTPCR] is increased itao Smad2 [KO]
    *** cells: mEFs in BMS
    *** source: 20595680-Fig-9d
  *** Tgfb1-gene mRNA[RTPCR] is unchanged itao Smad2 [RNAi]
    *** cells: mTECs in BMS
    *** source: 20595680-Fig-9c
  *** Tgfbi-gene mRNA[RTPCR] is detectable
    *** cells: mEFs in BMS
    *** reqs: Egr1 [KO]
    *** source: 15958557-Fig-1
  *** xTgfbR1(mnr)"CA"[tAb] prot-exp[WB] is increased itpo xPkcz
    *** cells: PC3U<xTgfbR1(mnr)"CA"> in BMS
    *** source: 21629263-Fig-5e
  *** xTgfbR1(mnr)"CA"[tAb]IP prot-exp[WB] is unchanged itpo xSmad7
    *** cells: COS7 in BMS
    *** unaffected by: xSmurf1 [addition]
    *** unaffected by: xSmurf1(del(22-37))"del-C2-domain" [addition]
    *** source: 12151385-Fig-4b
  *** xTgfbR1(mnr)"CA"[tAb]IP ubiq[tUbAb] is increased itpo xSmad7
    *** cells: HEK293T in BMS "treated with Lactacystin"
    *** enhanced by: xSmurf1 [addition]
    *** unaffected by: xSmurf1(del(22-37))"del-C2-domain" [addition]
    *** source: 12151385-Fig-3b
  *** xTgfbR1(mnr)"KD"[125I-Tgfb1-XL] copptby[WB] xSara[tAb] is detectable
    *** cells: COS1<xTgfbR2> in BMS
    *** enhanced by: xSmad2 [addition]
    *** source: 9865696-Fig-5c
  *** xTgfbR1(mnr)"KD"[125I-Tgfb1-XL] copptby[WB] xSara[tAb] is detectable
    *** cells: COS1<xTgfbR2> in BMS
    *** partially inhibited by: xSara(mnr)"del-SBD" [substitution]
    *** source: 9865696-Fig-5c
  *** xTgfbR1(mnr)"KD"[tAb] copptby[WB] xSnx1[tAb] is detectable
    *** cells: COS1 in BMLS
    *** source: 11279102(D)
  *** xTgfbR1(mnr)"KD"[tAb] copptby[WB] xSnx2[tAb] is detectable
    *** cells: COS1 in BMLS
    *** source: 11279102(D)
  *** xTgfbR1(mnr)"KD"[tAb] copptby[WB] xSnx3[tAb] is undetectable
    *** cells: COS1 in BMLS
    *** source: 11279102(D)
  *** xTgfbR1(mnr)"KD"[tAb] copptby[WB] xSnx4[tAb] is detectable
    *** cells: COS1 in BMLS
    *** source: 11279102(D)
  *** xTgfbR1(mnr)"KD"[tAb] copptby[WB] xSnx6[tAb] is detectable
    *** cells: COS1 in BMLS
    *** source: 11279102(D)
  *** xTgfbR1(mnr)"KD"[tAb] prot-exp[WB] is increased itpo xPkcz
    *** cells: PC3U<xTgfbR1(mnr)"KD"> in BMS
    *** source: 21629263-Fig-5e
  *** xTgfbR1(T204D)"CA"[tAb] copptby[WB] xSmad7[tAb] is detectable
    *** cells: COS1 in BMS
    *** enhanced by: xStrap [addition]
    *** source: 10757800(D)
  *** xTgfbR1(T204D)"CA"[tAb] copptby[WB] xStrap[tAb] is detectable
    *** cells: COS1<xSmad7> in BMS
    *** source: 10757800(D)
  *** xTgfbR1(T204D)"CA"[tAb] prot-exp[WB] is decreased itpo xSmurf2
    *** cells: HEK293T<xSmad7> in BMS
    *** reversed by: xSmurf2(C716A)"CIA" [substitution]
    *** source: 11163210-Fig-4b
  *** xTgfbR1(T204D)"CA"[tAb] prot-stability[35S-pulse-chase] is decreased itpo (xSmurf1 + xSmad7)
    *** cells: COS7 in BMS
    *** source: 11278251-Fig-4c
  *** xTgfbR1[125I-Tgfb1-XL] copptby[WB] xSara[tAb] is detectable
    *** cells: COS1<xTgfbR2> in BMS
    *** enhanced by: xSmad2 [addition]
    *** source: 9865696-Fig-5b
  *** xTgfbR1[125I-Tgfb1-XL] copptby[WB] xSara[tAb] is detectable
    *** cells: COS1<xTgfbR2> in BMS
    *** enhanced by: xTgfbR1(mnr)"KD" [substitution]
    *** source: 9865696-Fig-5b
  *** TgfbR1[125I-Tgfb1-XL] copptby[WB] xSmad7[tAb] is detectable
    *** cells: COS7 in BMS
    *** enhanced by: xSmurf1(C699A) [addition]
    *** unaffected by: xSmurf1(del(22-37)/C699A) [addition]
    *** source: 12151385-Fig-2b
  *** xTgfbR1[125I-Tgfb1-XL] copptby[WB] xSmad7[tAb] is detectable
    *** cells: COS7<xTgfbR2> in BMS
    *** unaffected by: xSmad7(del(207-211))"PY-domain-deleted" [substitution]
    *** source: 11278251-Fig-1d
  *** TgfbR1[125I-Tgfb1-XL] copptby[WB] xSmurf1(C699A)"CIA"[tAb] is detectable
    *** cells: COS7 in BMS
    *** enhanced by: xSmad7 [addition]
    *** source: 12151385-Fig-2b
  *** TgfbR1[125I-Tgfb1-XL] copptby[WB] xSmurf1(C699A)"CIA"[tAb] is detectable
    *** cells: COS7 in BMS
    *** inhibited by: xSmurf1(del(22-37)/C699A) [substitution]
    *** source: 12151385-Fig-2b
  *** TgfbR1[Ab] boundto(Snai1-gene)[ChIP] is detectable
    *** cells: PC3U in BMS
    *** source: 21629263-Fig-6h
  *** TgfbR1[Ab] copptby[WB] Sptbn1[Ab] is detectable
    *** cells: HEPG2 in BMS
    *** source: 12543979-Fig-2
  *** TgfbR1[biotin]IP surface-exp[biotin-labeling] is detectable-but unchanged itao Adam17 [RNAi]
    *** cells: HEPG2 in BMS
    *** source: 19595713-Fig-5a
  *** TgfbR1[biotin]IP surface-exp[biotin-labeling] is decreased itao Timp3 [RNAi]
    *** cells: T42 in BMS
    *** source: 22550340-Fig-S1b
  *** xTgfbR1[tAb] colocwith[IHC] Eea1[Ab] is detectable
    *** cells: COS7<xTgfbR2><xDnm1> in BMS "treated with Tgfb1 for 1 hr"
    *** inhibited by: xDnm1(K44E)"DN" [substitution]
    *** source: 12356868-Fig-2a
  *** xTgfbR1[tAb] copptby[WB] xAcvR2b[tAb] is undetectable
    *** cells: R1BL17 in BMS
    *** unaffected by: Inha (20 min) [stim]
    *** source: 8622651(D)
  *** xTgfbR1[tAb] copptby[WB] xAmhR2[Ab] is detectable
    *** cells: CHO in BMS
    *** unaffected by: Amh (45 min) [stim]
    *** source: 10854429(D)
  *** xTgfbR1[tAb] copptby[WB] xDab2[Ab] is detectable
    *** cells: COS7 in BMS
    *** unaffected by: xTgfbR1(mnr)"KD" [substitution]
    *** inhibited by: xTgfbR1(mnr)"CA" [substitution]
    *** source: 11387212(D)
  *** xTgfbR1[tAb] copptby[WB] xPmlc[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15356634-Fig-S8
  *** xTgfbR1[tAb] copptby[WB] xSnx6[tAb] is detectable
    *** cells: COS1 in BMLS
    *** inhibited by: xSnx6(del(PXdomain)) [substitution]
    *** source: 11279102(D)
  *** xTgfbR1[tAb] copptby[WB] xZfyve16[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 17272273-Fig-4d
  *** xTgfbR1[tAb] prot-exp[WB] is decreased itpo xSmurf2
    *** cells: HEK293T<xTgfbR2><xSmad7> in BMS
    *** reversed by: xSmurf2(C716A)"CIA" [substitution]
    *** source: 11163210-Fig-4b
  *** xTgfbR1[tAb] prot-exp[WB] is increased itpo xPkcz
    *** cells: PC3U<xTgfbR1> in BMS
    *** does not req: Smad4 [RNAi]
    *** source: 21629263-Fig-S7a
  *** xTgfbR1[tAb] prot-exp[WB] is unchanged itpo xSmurf2
    *** cells: HEK293T in BMS
    *** unaffected by: xTgfbR2 [addition]
    *** source: 11163210-Fig-4a
  *** xTgfbR1[tAb] prot-stability[35S-pulse-chase] is decreased itpo (xSmad7 + xSmurf2)
    *** cells: COS1 in BMS
    *** reqs: both [omissions]
    *** source: 11163210-Fig-4c
  *** xTgfbR1[tAb]IP IVKA(auto)[pYAb] is detectable
    *** cells: COS in BMS
    *** source: 17673906-Fig-6f
  *** xTgfbR1[tAb]IP prot-stability[35S-pulse-chase] is decreased itpo (xSmurf1 + Smad7)
    *** cells: COS7 in BMS
    *** reversed by: xSmurf1(del(22-37))"del-C2-domain" [substitution]
    *** source: 12151385-Fig-4d
  *** xTgfbR1[tAb]IP prot-stability[35S-pulse-chase] is decreased itpo xSmurf1
    *** cells: COS7 in BMS
    *** enhanced by: xSmad7 [addition]
    *** source: 12151385-Fig-4c
  *** TgfbR1{p34}[Ab] infraction(nuclear)[WB] is detectable
    *** cells: PC3U in BMS
    *** reqs: Pkcz [RNAi]
    *** source: 21629263-Fig-5d
  *** xTgfbR2(mnr)"KD"[tAb] copptby[WB] xSnx1[tAb] is undetectable
    *** cells: COS1 in BMLS
    *** source: 11279102(D)
  *** xTgfbR2(mnr)"KD"[tAb] copptby[WB] xSnx2[tAb] is detectable
    *** cells: COS1 in BMLS
    *** source: 11279102(D)
  *** xTgfbR2(mnr)"KD"[tAb] copptby[WB] xSnx3[tAb] is undetectable
    *** cells: COS1 in BMLS
    *** source: 11279102(D)
  *** xTgfbR2(mnr)"KD"[tAb] copptby[WB] xSnx4[tAb] is detectable
    *** cells: COS1 in BMLS
    *** source: 11279102(D)
  *** xTgfbR2(mnr)"KD"[tAb] copptby[WB] xSnx6[tAb] is detectable
    *** cells: COS1 in BMLS
    *** source: 11279102(D)
  *** xTgfbR2[125I-Tgfb1-XL] copptby[WB] xSara[tAb] is detectable
    *** cells: COS1<xTgfbR1(mnr)"KD"> in BMS
    *** enhanced by: xSmad2 [addition]
    *** source: 9865696-Fig-5c
  *** xTgfbR2[125I-Tgfb1-XL] copptby[WB] xSara[tAb] is detectable
    *** cells: COS1<xTgfbR1(mnr)"KD"> in BMS
    *** enhanced by: xSmad2 [addition]
    *** source: 9865696-Fig-6e
  *** xTgfbR2[125I-Tgfb1-XL] copptby[WB] xSara[tAb] is detectable
    *** cells: COS1<xTgfbR1(mnr)"KD"> in BMS
    *** partially inhibited by: xSara(595-1323) [substitution]
    *** partially inhibited by: xSara(665-1323) [substitution]
    *** partially inhibited by: xSara(705-1323) [substitution]
    *** partially inhibited by: xSara(1-704) [substitution]
    *** partially inhibited by: xSara(1-664) [substitution]
    *** partially inhibited by: xSara(del(665-704))"del-SBD" [substitution]
    *** partially inhibited by: xSara(del(597-664))"del-FYVE" [substitution]
    *** inhibited by: xSara(del(597-706))"del-SBD/FYVE" [substitution]
    *** source: 9865696-Fig-6e
  *** xTgfbR2[125I-Tgfb1-XL] copptby[WB] xSara[tAb] is detectable
    *** cells: COS1<xTgfbR1(mnr)"KD"> in BMS
    *** partially inhibited by: xSara(mnr)"del-SBD" [substitution]
    *** source: 9865696-Fig-5c
  *** xTgfbR2[125I-Tgfb1-XL] copptby[WB] xSara[tAb] is detectable
    *** cells: COS1<xTgfbR1> in BMS
    *** enhanced by: xSmad2 [addition]
    *** source: 9865696-Fig-5b
  *** xTgfbR2[125I-Tgfb1-XL] copptby[WB] xSara[tAb] is detectable
    *** cells: COS1<xTgfbR1> in BMS
    *** enhanced by: xTgfbR1(mnr)"KD" [substitution]
    *** source: 9865696-Fig-5b
  *** TgfbR2[125I-Tgfb1-XL] copptby[WB] xSmad7[tAb] is detectable
    *** cells: COS7 in BMS
    *** enhanced by: xSmurf1(C699A) [addition]
    *** unaffected by: xSmurf1(del(22-37)/C699A) [addition]
    *** source: 12151385-Fig-2b
  *** xTgfbR2[125I-Tgfb1-XL] copptby[WB] xSmad7[tAb] is detectable
    *** cells: COS7<xTgfbR1> in BMS
    *** unaffected by: xSmad7(del(207-211))"PY-domain-deleted" [substitution]
    *** source: 11278251-Fig-1d
  *** TgfbR2[125I-Tgfb1-XL] copptby[WB] xSmurf1(C699A)"CIA"[tAb] is detectable
    *** cells: COS7 in BMS
    *** enhanced by: xSmad7 [addition]
    *** source: 12151385-Fig-2b
  *** TgfbR2[125I-Tgfb1-XL] copptby[WB] xSmurf1(C699A)"CIA"[tAb] is detectable
    *** cells: COS7 in BMS
    *** inhibited by: xSmurf1(del(22-37)/C699A) [substitution]
    *** source: 12151385-Fig-2b
  *** TgfbR2[Ab] copptby[WB] Snx2[Ab] is detectable
    *** cells: HEPG2 in BMLS
    *** source: 11279102(D)
  *** TgfbR2[Ab] prot-exp[WB] is detectable-but unchanged itao Adam17 [RNAi]
    *** cells: A549 in BMS
    *** source: 19595713-Fig-5a
  *** TgfbR2[Ab] prot-exp[WB] is detectable-but unchanged itao Adam17 [RNAi]
    *** cells: HACAT in BMS
    *** source: 19595713-Fig-5a
  *** TgfbR2[Ab] prot-exp[WB] is detectable-but unchanged itao Adam17 [RNAi]
    *** cells: HACAT in BMS
    *** source: 19595713-Fig-5b
  *** TgfbR2[Ab] prot-exp[WB] is detectable-but unchanged itao Adam17 [RNAi]
    *** cells: HELA in BMS
    *** source: 19595713-Fig-5a
  *** TgfbR2[Ab] prot-exp[WB] is detectable-but unchanged itao Adam17 [RNAi]
    *** cells: HEPG2 in BMS
    *** source: 19595713-Fig-5a
  *** TgfbR2[Ab] prot-exp[WB] is detectable-but unchanged itao Adam17 [RNAi]
    *** cells: MDAMB468 in BMS
    *** source: 19595713-Fig-5a
  *** TgfbR2[Ab] prot-exp[WB] is detectable-but unchanged itao Adam17 [RNAi]
    *** cells: T42 in BMS
    *** source: 19595713-Fig-5a
  *** TgfbR2[biotin]IP surface-exp[biotin-labeling] is detectable-but unchanged itao Adam17 [RNAi]
    *** cells: A549 in BMS
    *** source: 19595713-Fig-5a
  *** TgfbR2[biotin]IP surface-exp[biotin-labeling] is detectable-but unchanged itao Adam17 [RNAi]
    *** cells: HACAT in BMS
    *** source: 19595713-Fig-5a
  *** TgfbR2[biotin]IP surface-exp[biotin-labeling] is detectable-but unchanged itao Adam17 [RNAi]
    *** cells: HACAT in BMS
    *** source: 19595713-Fig-5b
  *** TgfbR2[biotin]IP surface-exp[biotin-labeling] is detectable-but unchanged itao Adam17 [RNAi]
    *** cells: HELA in BMS
    *** source: 19595713-Fig-5a
  *** TgfbR2[biotin]IP surface-exp[biotin-labeling] is detectable-but unchanged itao Adam17 [RNAi]
    *** cells: HEPG2 in BMS
    *** source: 19595713-Fig-5a
  *** TgfbR2[biotin]IP surface-exp[biotin-labeling] is detectable-but unchanged itao Adam17 [RNAi]
    *** cells: MDAMB468 in BMS
    *** source: 19595713-Fig-5a
  *** TgfbR2[biotin]IP surface-exp[biotin-labeling] is detectable-but unchanged itao Adam17 [RNAi]
    *** cells: T42 in BMS
    *** source: 19595713-Fig-5a
  *** xTgfbR2[tAb] colocwith[IHC] Cav1[Ab] is detectable
    *** cells: MV1LU in BMS
    *** unaffected by: Tgfb1 (15,60 min) [stim]
    *** source: 12717440-Fig-1a
  *** xTgfbR2[tAb] colocwith[IHC] Eea1[Ab] is detectable
    *** cells: COS7<xTgfbR1><xDnm1> in BMS "treated with Tgfb1 for 1 hr"
    *** inhibited by: xDnm1(K44E)"DN" [substitution]
    *** source: 12356868-Fig-2b
  *** xTgfbR2[tAb] colocwith[IHC] Eea1[Ab] is detectable
    *** cells: MV1LU in BMS
    *** unaffected by: Tgfb1 (15, 60 min) [stim]
    *** unaffected by: Nystatin [addition]
    *** inhibited by: xEps15(mnr)"DN" [addition]
    *** inhibited by: xDnm1(K44A)"DN" [addition]
    *** source: 12717440-Fig-1a,2a
  *** xTgfbR2[tAb] copptby[WB] xAcvRl1[Ab] is detectable
    *** cells: COS1 in BMS
    *** source: 10187774(D)
  *** xTgfbR2[tAb] copptby[WB] xDab2[Ab] is detectable
    *** cells: COS7 in BMS
    *** unaffected by: xTgfbR2(mnr)"KD" [substitution]
    *** source: 11387212(D)
  *** xTgfbR2[tAb] copptby[WB] xPmlc[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 15356634-Fig-S8
  *** xTgfbR2[tAb] copptby[WB] xSnx6[tAb] is detectable
    *** cells: COS1 in BMLS
    *** source: 11279102(D)
  *** xTgfbR2[tAb] copptby[WB] xTgfbR1[tAb] is detectable
    *** cells: mMesangialCells<xTak1><xTgfbR1><xTgfbR2> in BMS
    *** unaffected by: xTgfbR1(T185V/T186V/S187A/S189A/S191A)"GS" [substitution]
    *** unaffected by: xTgfbR1(T198D)"CA" [substitution]
    *** source: 19556242-Fig-4b
  *** xTgfbR2[tAb] prot-exp[WB] is decreased itpo xSmurf2
    *** cells: HEK293T<xTgfbR1><xSmad7> in BMS
    *** reversed by: xSmurf2(C716A)"CIA" [substitution]
    *** source: 11163210-Fig-4b
  *** xTgfbR2[tAb] prot-exp[WB] is unchanged itpo xSmurf2
    *** cells: HEK293T in BMS
    *** unaffected by: xTgfbR1 [addition]
    *** source: 11163210-Fig-4a
  *** xTgfbR2[tAb] prot-stability[35S-pulse-chase] is unchanged itpo (xSmad7 + xSmurf2)
    *** cells: COS1 in BMS
    *** source: 11163210-Fig-4c
  *** xTgfbR2[tAb]IP cleavage[WB] is unchanged itpo xAdam17
    *** cells: CHO<xTgfbR2> in BMLS
    *** unaffected by: xAdam17(E406A) [substitution]
    *** source: 19595713-Fig-3a
  *** xTgfbRap1(del(1-474))[tAb] copptby[WB] xTgfbR1(T204D)"CA"[tAb] is detectable
    *** cells: COS1 in BMLS
    *** source: 11278302(D)
  *** xTgfbRap1[tAb] colocwith[IHC] xTgfbR1(K232R)"KD"[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 11278302(D)
  *** xTgfbRap1[tAb] colocwith[IHC] xTgfbR1(T204D)"CA"[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 11278302(D)
  *** xTgfbRap1[tAb] colocwith[IHC] xTgfbR2(K227R)"KD"[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 11278302(D)
  *** xTgfbRap1[tAb] copptby[WB] TgfbR1[tAb] is increased itpo xTgfbR1(K232R)"KD"
    *** cells: COS1 in BMLS
    *** source: 11278302(D)
  *** xTgfbRap1[tAb] copptby[WB] TgfbR1[tAb] is increased itpo xTgfbR1(K232R)"KD"
    *** cells: COS1<xTgfbR2> in BMLS
    *** unaffected by: Tgfb1 (12 hr) [stim]
    *** source: 11278302(D)
  *** xTgfbRap1[tAb] copptby[WB] xAcvR1(mnr)"KD"[tAb] is undetectable
    *** cells: COS1 in BMS
    *** source: 11278302(D)
  *** xTgfbRap1[tAb] copptby[WB] xAcvR1b(mnr)"KD"[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 11278302(D)
  *** xTgfbRap1[tAb] copptby[WB] xAcvR2b[tAb] is detectable
    *** cells: COS1 in BMS
    *** unaffected by: xAcvR2(mnr)"KD" [substitution]
    *** unaffected by: xAcvR1b(mnr)"KD" [addition]
    *** inhibited by: xAcvR1b(mnr)"CA" [addition]
    *** source: 11278302(D)
  *** xTgfbRap1[tAb] copptby[WB] xAcvRl1(mnr)"KD"[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 11278302(D)
  *** xTgfbRap1[tAb] copptby[WB] xBmpR1a(mnr)"KD"[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 11278302(D)
  *** xTgfbRap1[tAb] copptby[WB] xBmpR1b(mnr)"KD"[tAb] is undetectable
    *** cells: COS1 in BMS
    *** source: 11278302(D)
  *** xTgfbRap1[tAb] copptby[WB] xBmpR2[tAb] is undetectable
    *** cells: COS1 in BMS
    *** source: 11278302(D)
  *** xTgfbRap1[tAb] copptby[WB] xSmad2[tAb] is undetectable
    *** cells: COS1 in BMS
    *** source: 11278302(D)
  *** xTgfbRap1[tAb] copptby[WB] xSmad3[tAb] is undetectable
    *** cells: COS1 in BMS
    *** source: 11278302(D)
  *** xTgfbRap1[tAb] copptby[WB] xSmad4[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 11278302(D)
  *** xTgfbRap1[tAb] copptby[WB] xSmad4[tAb] is increased itpo xTgfbR1(T204D)"CA"
    *** cells: COS1 in BMS
    *** inhibited by: xSmad2 [addition]
    *** unaffected by: xSmad2(S464A/S465A/S467A) [substitution]
    *** source: 11278302(D)
  *** xTgfbRap1[tAb] copptby[WB] xSmad5[tAb] is undetectable
    *** cells: COS1 in BMS
    *** source: 11278302(D)
  *** xTgfbRap1[tAb] copptby[WB] xSmad6[tAb] is undetectable
    *** cells: COS1 in BMS
    *** source: 11278302(D)
  *** xTgfbRap1[tAb] copptby[WB] xSmad7[tAb] is undetectable
    *** cells: COS1 in BMS
    *** source: 11278302(D)
  *** xTgfbRap1[tAb] copptby[WB] xSmad9[tAb] is undetectable
    *** cells: COS1 in BMS
    *** source: 11278302(D)
  *** xTgfbRap1[tAb] copptby[WB] xTgfbR1(K232R)"KD"[tAb] is detectable
    *** cells: COS1 in BMS
    *** source: 11278302(D)
  *** xTgfbRap1[tAb] copptby[WB] xTgfbR1(T204D)"CA"[tAb] is undetectable
    *** cells: COS1 in BMLS
    *** source: 11278302(D)
  *** xTgfbRap1[tAb] copptby[WB] xTgfbR1[tAb] is detectable
    *** cells: COS1 in BMLS
    *** source: 12941698-Fig-3a
  *** xTgfbRap1[tAb] copptby[WB] xTgfbR2[tAb] is detectable
    *** cells: COS1 in BMLS
    *** enhanced by: xTgfbR1(mnr)"KD" [addition]
    *** source: 12941698-Fig-3a
  *** xTgfbRap1[tAb] copptby[WB] xTgfbR2[tAb] is increased itpo xTgfbR2(K227R)"KD"
    *** cells: COS1 in BMLS
    *** source: 11278302(D)
  *** xTgfbRap1[tAb] copptby[WB] xTgfbR2[tAb] is increased itpo xTgfbR2(K227R)"KD"
    *** cells: COS1<xTgfbR1> in BMLS
    *** unaffected by: Tgfb1 (12 hr) [stim]
    *** source: 11278302(D)
  *** Thbs2-gene mRNA[RTPCR] is detectable
    *** cells: mEFs in BMS
    *** reqs: Egr1 [KO]
    *** source: 15958557-Fig-1
  *** DNA-synthesis[3H-Thymidine] is decreased itao Gfi1 [RNAi]
    *** cells: BAF3 in BMS
    *** source: 20190815-Fig-8a
  *** DNA-synthesis[3H-Thymidine] is detectable
    *** cells: CT6 in BMS "containing IL2"
    *** inhibited by: SB203580 [pretreatment]
    *** source: 9169478-Fig-3a
  *** DNA-synthesis[3H-Thymidine] is detectable
    *** cells: CT6 in BMS "containing IL7"
    *** inhibited by: SB203580 [pretreatment]
    *** source: 9169478-Fig-3a
  *** DNA-synthesis[3H-Thymidine] is detectable
    *** cells: mSpCs<Cd4~pos> in BMS "treated with PMA + Ionomycin"
    *** unaffected by: kIL4R(Y500F) [knockin]
    *** source: 14557412-Fig-3a
  *** DNA-synthesis[3H-Thymidine] is detectable
    *** cells: mSpCs<Cd4~pos> in BMS "treated with TcRb + IL2"
    *** unaffected by: kIL4R(Y500F) [knockin]
    *** source: 14557412-Fig-3a
  *** DNA-synthesis[3H-Thymidine] is detectable
    *** cells: TS1<xIL2Ra><xIL2Rb> in BMS "containing IL2"
    *** does not req: Pkca [AntiSense]
    *** does not req: Pkcb [AntiSense]
    *** does not req: Pkcq [AntiSense]
    *** does not req: Pkcd [AntiSense]
    *** reqs: Pkce [AntiSense]
    *** partially reqs: Pkcz [AntiSense]
    *** source: 7737351-Fig-5
  *** DNA-synthesis[3H-Thymidine] is detectable
    *** cells: TS1<xIL2Ra><xIL2Rb> in BMS "containing IL4"
    *** does not req: Pkca [AntiSense]
    *** does not req: Pkcb [AntiSense]
    *** does not req: Pkcq [AntiSense]
    *** does not req: Pkcd [AntiSense]
    *** does not req: Pkce [AntiSense]
    *** does not req: Pkcz [AntiSense]
    *** source: 7737351-Fig-6
  *** DNA-synthesis[3H-Thymidine] is detectable
    *** cells: TS1<xIL2Ra><xIL2Rb> in BMS "IL2-deprived" "treated with IL2 for 30 min"
    *** partially inhibited by: ToxinB [pretreatment]
    *** source: 9029085-Fig-1
  *** DNA-synthesis[3H-Thymidine] is detectable
    *** cells: TS1<xIL2Ra><xIL2Rb> in BMS "IL2-deprived" "treated with IL4 for 30 min"
    *** unaffected by: ToxinB [pretreatment]
    *** source: 9029085-Fig-1
  *** DNA-synthesis[3H-Thymidine] is detectable
    *** cells: TS1<xIL2Rb> in BMS "containing IL2"
    *** does not req: Pkca [AntiSense]
    *** partially reqs: Pkcb [AntiSense]
    *** does not req: Pkcq [AntiSense]
    *** does not req: Pkcd [AntiSense]
    *** does not req: Pkce [AntiSense]
    *** partially reqs: Pkcz [AntiSense]
    *** source: 7737351-Fig-5
  *** DNA-synthesis[3H-Thymidine] is detectable
    *** cells: TS1<xIL2Rb> in BMS "containing IL4"
    *** does not req: Pkca [AntiSense]
    *** does not req: Pkcb [AntiSense]
    *** does not req: Pkcq [AntiSense]
    *** does not req: Pkcd [AntiSense]
    *** does not req: Pkce [AntiSense]
    *** does not req: Pkcz [AntiSense]
    *** source: 7737351-Fig-6
  *** DNA-synthesis[3H-Thymidine] is increased itao Stat4 [KO]
    *** cells: mSpCs in BMS "activated with anti-Cd3 for 48 hr"
    *** source: 11120802-Fig-3c
  *** DNA-synthesis[3H-Thymidine] is increased itpo xStam
    *** cells: BAFB03<xIL2Rb><xIL2Rg> in BMS
    *** partially inhibited by: xStam(del(216-267))"DSH3" [addition]
    *** source: 10899310-Fig-5c
  *** DNA-synthesis[3H-Thymidine] is increased itpo xStam2
    *** cells: BAFB03<xIL2Rb><xIL2Rg> in BMS
    *** inhibited by: xStam2(del(209-256))"2DSH3" [substitution]
    *** unaffected by: xStam2(del(349-377))"2DIT" [substitution]
    *** unaffected by: xStam2(1-343)"2DY2" [substitution]
    *** source: 10899310-Fig-5a
  *** DNA-synthesis[3H-Thymidine] is increased itpo xStam2
    *** cells: BAFB03<xIL2Rb><xIL2Rg> in BMS
    *** partially inhibited by: xStam2(del(209-256))"2DSH3" [substitution]
    *** source: 10899310-Fig-5c
*** Tiam1--
  *** rTiam1(1033-1606)[His] boundby[WB] rCdc42{NucFree}[GST] is undetectable
    *** cells: none
    *** source: 11595749-Fig-1c
  *** Tiam1[Ab] locatedin(cellmembrane)[IHC] is increased itpo xPpp1r9b
    *** cells: COS7 in BMS
    *** source: 12531897(D)
  *** xTiam1[tAb] snaggedby[WB] rCdc42(G15N)"NucFree"[GST] is undetectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-1
  *** xTiam1[tAb] snaggedby[WB] rRhoa(G17A)"NucFree"[GST] is undetectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-1
  *** xTiam1[tAb] snaggedby[WB] rRhog(G15N)"NucFree"[GST] is undetectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-1
*** Ticam2--
  *** rTicam2[32P] phos[32P-ATP] is increased by rPkce
    *** cells: none
    *** source: 16757566-Fig-1d
  *** rTicam2[32P] phos[32P-ATP] is unchanged by rPkcz
    *** cells: none
    *** source: 16757566-Fig-1d
  *** xTicam2[tAb] colocwith[IHC] xRab5s[tAb] is detectable
    *** cells: mBMMs in BMS
    *** source: 18297073-Fig-2a
  *** xTicam2[tAb] copptby[WB] Irf3[Ab] is detectable
    *** cells: HEK293T in BMS
    *** source: 14517278-Fig-3b
  *** xTicam2[tAb] copptby[WB] xIL1R1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12721283-Fig-2a
  *** xTicam2[tAb] copptby[WB] xIL1Rap[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12721283-Fig-2a
  *** xTicam2[tAb] copptby[WB] xIrak1[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** inhibited by: xIrak1(K239S)"KD" [substitution]
    *** source: 12721283-Fig-3a
  *** xTicam2[tAb] copptby[WB] xIrak2[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12721283-Fig-3a
  *** xTicam2[tAb] copptby[WB] xIrak3[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12721283-Fig-3a
  *** xTicam2[tAb] copptby[WB] xIrak4[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** inhibited by: xIrak4(K213S)"KD" [substitution]
    *** source: 12721283-Fig-3a
  *** xTicam2[tAb] copptby[WB] xTirap[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12721283-Fig-2b
  *** xTicam2[tAb] copptby[WB] xTLR2[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 12721283-Fig-2a
  *** xTicam2[tAb] copptby[WB] xTLR2[tAb] is undetectable
    *** cells: HEK293<xMd2> in BMS
    *** source: 14519765(D)
  *** xTicam2[tAb] copptby[WB] xTLR3[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 14519765(D)
  *** xTicam2[tAb] copptby[WB] xTLR3[tAb] is undetectable
    *** cells: HELA in BMS
    *** source: 14517278-Fig-6c
  *** xTicam2[tAb] copptby[WB] xTLR4[tAb] is detectable
    *** cells: HEK293<xMd2> in BMS
    *** unaffected by: Lps (tnr) [stim]
    *** source: 14519765(D)
  *** xTicam2[tAb] copptby[WB] xTLR4[tAb] is detectable
    *** cells: HELA in BMS
    *** inhibited by: xTicam2(C113H) [substitution]
    *** source: 14517278-Fig-6c
  *** xTicam2[tAb] copptby[WB] xTLR4[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 12721283-Fig-2a
  *** xTicam2[tAb] copptby[WB] xTraf5[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 12721283-Fig-3b
  *** xTicam2[tAb] copptby[WB] xTraf6[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12721283-Fig-3b
  *** xTicam2[tAb] copptby[WB] xTrif[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12721283-Fig-2b
  *** xTicam2[tAb] oligomerization[2TagPpt] is detectable
    *** cells: HEK293 in BMS
    *** source: 14519765(D)
  *** xTicam2[XFP] colocwith[IHC] xTLR4[XFP] is detectable
    *** cells: HEK293 in BMS
    *** source: 16603631-Fig-1a
  *** xTicam2[XFP] colocwith[IHC] xTLR9[XFP] is undetectable
    *** cells: HEK293 in BMS
    *** source: 16603631-Fig-1a
  *** Tifa[Ab] copptby[WB] Traf6[Ab] is detectable
    *** cells: 70Z in BMS
    *** unaffected by: IL1 (5 min) [stim]
    *** source: 12566447-Fig-5a
  *** xTifa[tAb] copptby[WB] Traf6[Ab] is detectable
    *** cells: mEFs in BMS
    *** source: 12566447-Fig-5b
  *** Timp1-gene mRNA[RTPCR] is unchanged itao Smad2 [KO]
    *** cells: mEFs in BMS
    *** source: 20595680-Fig-6c
  *** Timp1-gene mRNA[RTPCR] is unchanged itao Smad2 [RNAi]
    *** cells: mTECs in BMS
    *** source: 20595680-Fig-6b
*** Tip60--
  *** Tip60[Ab] boundto(Cdkn1b-gene)[ChIP] is detectable
    *** cells: HELA in BMS
    *** does not req: Arrb1 [RNAi]
    *** unaffected by: xArrb1 [addition]
    *** unaffected by: xArrb1(Q394L) [addition]
    *** source: 16325578-Fig-4a
  *** Tip60[Ab] boundto(Cdkn1b-gene)[ChIP] is detectable
    *** cells: mEFs<Arrb1~null><Arrb2~null><xArrb1> in BMS
    *** source: 16325578-Fig-4a
  *** Tip60[Ab] boundto(Fos-gene)[ChIP] is detectable
    *** cells: HELA in BMS
    *** does not req: Arrb1 [RNAi]
    *** unaffected by: xArrb1 [addition]
    *** unaffected by: xArrb1(Q394L) [addition]
    *** source: 16325578-Fig-4a
  *** Tip60[Ab] boundto(Fos-gene)[ChIP] is detectable
    *** cells: mEFs<Arrb1~null><Arrb2~null><xArrb1> in BMS
    *** source: 16325578-Fig-4a
  *** Tip60[Ab] boundto(Jun-gene)[ChIP] is undetectable
    *** cells: HELA in BMS
    *** source: 16325578-Fig-4a
  *** Tip60[Ab] boundto(Jun-gene)[ChIP] is undetectable
    *** cells: mEFs<Arrb1~null><Arrb2~null><xArrb1> in BMS
    *** source: 16325578-Fig-4a
  *** Tip60[Ab] copptby[WB] Atm[Ab] is detectable
    *** cells: HELA in BMS
    *** source: 16141325-Fig-2d
  *** Tip60[Ab] copptby[WB] Prkdc[Ab] is detectable
    *** cells: HELA in BMS
    *** source: 16603769-Fig-3a
  *** Tip60[Ab] copptby[WB] Trrap[Ab] is detectable
    *** cells: HELA in BMS
    *** source: 16141325-Fig-2e
  *** Tip60[Ab] copptby[WB] xAtm[Ab] is detectable
    *** cells: GM5849<Atm~fmut><xAtm> in BMS
    *** unaffected by: xAtm(A3039Q/W3052Q)"FATC4" [substitution]
    *** partially inhibited by: xAtm(L3035A/W3052A)"FATC3" [substitution]
    *** inhibited by: xAtm(V3032A/L3045A)"FATC2" [substitution]
    *** inhibited by: xAtm(V3032A/L3035A/L3045A/W3052A)"FATC1" [substitution]
    *** source: 16141325-Fig-4b
  *** xTip60[Ab] copptby[WB] xTp53[tAb] is detectable
    *** cells: H1299<Tp53~null><xTp53><xCbp> in BMS
    *** unaffected by: xTp53(K120R/K164R/K370R/K372R/K373R/K381R/K382R/K386R)"8KR" [substitution]
    *** source: 18485870-Fig-S3b
  *** xTip60[Ab]IP IVHatAct(HistH4)[ELISA] is detectable
    *** cells: HELA<xTip60> in BMS
    *** inhibited by: xTip60(Q377E/G380E)"CIA" [substitution]
    *** source: 16141325-Fig-3a
  *** rTip60[tAb] boundby[WB] sHistH3(mnr)"K9me3"[biotin] is detectable
    *** cells: none
    *** inhibited by: sHistH3(2-22) [substitution]
    *** inhibited by: sHistH3(mnr)"K4me3" [substitution]
    *** inhibited by: sHistH3(mnr)"K27me3" [substitution]
    *** source: 19783983-Fig-3e
  *** rTip60[tAb] boundby[WB] sHistH3(mnr)"K9me3"[biotin] is detectable
    *** cells: none
    *** inhibited by: sHistH3(mnr)"K36me3" [substitution]
    *** source: 19783983-Fig-S5e
  *** rTip60[tAb] boundby[WB] sHistH3(mnr)"K9me3"[biotin] is detectable
    *** cells: none
    *** inhibited by: xTip60(Y47A)"CD" [substitution]
    *** source: 19783983-Fig-3e
  *** rTip60[tAb] boundby[WB] sHistH3(mnr)"K9me3"[biotin] is detectable
    *** cells: none
    *** inhibited by: xTip60(Y47A)"CD" [substitution]
    *** source: 19783983-Fig-S6a
  *** xTip60[tAb] snaggedby[WB] sHistH3(mnr)"K9me3"[biotin] is detectable
    *** cells: HELAS3<xTip60> in BMS "nuclear-extracts"
    *** inhibited by: sHistH3(2-22) [substitution]
    *** inhibited by: sHistH3(22-43) [substitution]
    *** inhibited by: sHistH3(mnr)"K4me3" [substitution]
    *** inhibited by: sHistH3(mnr)"K27me3" [substitution]
    *** partially inhibited by: sHistH3(mnr)"K36me3" [substitution]
    *** source: 19783983-Fig-S5d
  *** xTip60[tAb] snaggedby[WB] sHistH3(mnr)"K9me3"[biotin] is detectable
    *** cells: NotReported<xTip60> in BMS
    *** inhibited by: sHistH3(2-22) [substitution]
    *** inhibited by: sHistH3(22-43) [substitution]
    *** inhibited by: sHistH3(mnr)"K4me2" [substitution]
    *** inhibited by: sHistH3(mnr)"K9me2" [substitution]
    *** inhibited by: sHistH3(mnr)"K27me2" [substitution]
    *** inhibited by: sHistH3(mnr)"K36me2" [substitution]
    *** inhibited by: sHistH3(mnr)"K4me3" [substitution]
    *** inhibited by: sHistH3(mnr)"K27me3" [substitution]
    *** inhibited by: sHistH3(mnr)"K36me3" [substitution]
    *** source: 19783983-Fig-3c
  *** xTip60[tAb] snaggedby[WB] sHistH3(mnr)"K9me3"[biotin] is detectable
    *** cells: NotReported<xTip60> in BMS
    *** inhibited by: xTip60(Y47A)"CD" [substitution]
    *** source: 19783983-Fig-3d
  *** xTip60[tAb]IP IVHatAct(HistH4)[ELISA] is increased by pHistH3
    *** cells: NotReported<xTip60> in BMS
    *** inhibited by: xTip60(Y47A)"CD" [substitution]
    *** source: 19783983-Fig-S4c
  *** xTip60[tAb]IP IVHatAct(HistH4)[ELISA] is increased by pHistH3
    *** cells: NotReported<xTip60> in BMS
    *** source: 19783983-Fig-3a
  *** xTip60[tAb]IP IVHatAct(HistH4)[ELISA] is increased by rHistH3{methyl}
    *** cells: NotReported<xTip60> in BMS
    *** inhibited by: rHistH3 [substitution]
    *** source: 19783983-Fig-S4b
  *** xTip60[tAb]IP IVHatAct(HistH4)[ELISA] is increased by sHistH3(2-22)
    *** cells: NotReported<xTip60> in BMS
    *** inhibited by: sHistH3(mnr)"K4me2" [substitution]
    *** unaffected by: sHistH3(mnr)"K9me2" [substitution]
    *** inhibited by: sHistH3(mnr)"K27me2" [substitution]
    *** inhibited by: sHistH3(mnr)"K36me2" [substitution]
    *** inhibited by: sHistH3(mnr)"K79me2" [substitution]
    *** unaffected by: sHistH3(mnr)"K4me3" [substitution]
    *** enhanced by: sHistH3(mnr)"K9me3" [substitution]
    *** unaffected by: sHistH3(mnr)"K27me3" [substitution]
    *** enhanced by: sHistH3(mnr)"K36me3" [substitution]
    *** unaffected by: sHistH3(mnr)"K79me3" [substitution]
    *** source: 19783983-Fig-3a
  *** rTip60[tAb]IP IVHatAct(HistH4)[ELISA] is increased by sHistH3(mnr)"K9me3"
    *** cells: none
    *** inhibited by: rTip60(Y47A)"CD" [substitution]
    *** source: 19783983-Fig-S6c
  *** xTip60[tAb]IP IVHatAct(HistH4)[ELISA] is increased by sHistH3(mnr)"K9me3"
    *** cells: NotReported<xTip60> in BMS
    *** inhibited by: xTip60(Y47A)"CD" [substitution]
    *** source: 19783983-Fig-3b
  *** xTip60[tAb]IP IVHatAct(HistH4)[ELISA] is increased by sHistH3(mnr)"K36me3"
    *** cells: NotReported<xTip60> in BMS
    *** inhibited by: xTip60(Y47A)"CD" [substitution]
    *** source: 19783983-Fig-3b
  *** xTiprl[tAb] copptby[WB] xTak1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xTab1 [addition]
    *** source: 18456659-Fig-3a
  *** xTiprl[tAb] copptby[WB] xTak1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xTiprl(1-116) [substitution]
    *** unaffected by: xTiprl(1-156) [substitution]
    *** unaffected by: xTiprl(1-231) [substitution]
    *** unaffected by: xTiprl(F254A) [substitution]
    *** unaffected by: xTiprl(F254A/P255A) [substitution]
    *** source: 18456659-Fig-4a
  *** xTiprl[tAb]IP ubiq[tUbAb] is detectable
    *** cells: HEK293T<xUbiq> in BMS
    *** unaffected by: xTiprl(F254A) [substitution]
    *** inhibited by: xTiprl(F254A/P255A) [substitution]
    *** source: 18456659-Fig-5a
  *** rTirap[32P] phos[32P-ATP] is increased by rBtk
    *** cells: none
    *** inhibited by: rTirap(Y86F/Y106F/Y187F) [substitution]
    *** source: 16439361(D)
  *** rTirap[32P] phos[32P-ATP] is unchanged by rPkce
    *** cells: none
    *** source: 16757566-Fig-1d
  *** rTirap[Ab] boundby[WB] rTLR4[GST] is detectable
    *** cells: none
    *** unaffected by: rTLR4(P147H) [substitution]
    *** source: 12888566-Fig-3f
  *** Tirap[Ab] copptby[WB] Casp1[Ab] is detectable
    *** cells: THP1 in BMS
    *** source: 17360653(D)
  *** xTirap[tAb] colocwith[IHC] xRab5s[tAb] is undetectable
    *** cells: mBMMs in BMS
    *** source: 18297073-Fig-2b
  *** xTirap[tAb] copptby[WB] xBtk[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 12724322(D)
  *** xTirap[tAb] copptby[WB] xCasp1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xTirap(D198A)"cleavage-site-mut" [substitution]
    *** source: 17360653(D)
  *** xTirap[tAb] copptby[WB] xSocs1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 16415872-Fig-2a
  *** xTirap[tAb] copptby[WB] xTicam2[tAb] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xTirap(P125H) [substitution]
    *** source: 14517278-Fig-6b
  *** xTirap[tAb] copptby[WB] xTLR3[tAb] is undetectable
    *** cells: HELA in BMS
    *** source: 14517278-Fig-6c
  *** xTirap[tAb] copptby[WB] xTLR4[Ab] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: rTLR4(P714H)"CA" [substitution]
    *** unaffected by: xTirap(P125H) [substitution]
    *** source: 12888566-Fig-3e,4e
  *** xTirap[tAb] copptby[WB] xTLR4[tAb] is detectable
    *** cells: HELA in BMS
    *** source: 14517278-Fig-6c
  *** xTirap[tAb] copptby[WB] xTrif[tAb] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xTirap(P125H) [substitution]
    *** source: 14517278-Fig-6b
  *** xTirap[tAb] oligomerization[2TagPpt] is detectable
    *** cells: HEK293T in BMS
    *** source: 11526399(D)
  *** xTirap[tAb] phos[WBMS] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xTirap(Y86F/Y106F/Y187F) [substitution]
    *** unaffected by: xTirap(Y159F/Y195F/Y196F) [substitution]
    *** source: 16439361(D)
  *** xTirap[tAb] prot-exp[WB] is decreased itpo xSocs1
    *** cells: HEK293T in BMS
    *** source: 16415872-Fig-2b
  *** xTirap[tAb] snaggedby[WB] PolyIC[agarose] is undetectable
    *** cells: HEK293 in BMS
    *** source: 16210631-Fig-6b
  *** xTirap[tAb] snaggedby[WB] rTLR4[GST] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: rTLR4(P714H)"CA" [substitution]
    *** unaffected by: xTirap(P125H) [substitution]
    *** source: 12888566-Fig-3c,4d
  *** xTirap[tAb]IP ubiq[tUbAb] is increased itpo xSocs1
    *** cells: HEK293T<xUbiq> in BMS "treated with MG132"
    *** source: 16415872-Fig-3a
*** Tlns--
  *** Tlns[Ab] copptby[WB] Apc[Ab] is undetectable
    *** cells: HELAS3 in BMS
    *** source: 20224554-Fig-5f
  *** Tlns[Ab] copptby[WB] Dvls[Ab] is undetectable
    *** cells: HELAS3 in BMS
    *** source: 20224554-Fig-5e
  *** Tlns[Ab] snaggedby[WB] rPak1[GST] is undetectable
    *** cells: 3Y1 in BMS
    *** source: 11096073-Fig-1a
  *** Tlns[Ab] snaggedby[WB] rPak3[GST] is undetectable
    *** cells: 3Y1 in BMS
    *** source: 11096073-Fig-1a
  *** Tlns[Ab] snaggedby[WB] rPxn[GST] is detectable
    *** cells: HELA in BMS
    *** source: 9054445-Fig-3a
  *** Tlns[Ab] snaggedby[WB] rPxn[GST] is detectable
    *** cells: U937 in BMS
    *** source: 9054445-Fig-3a
  *** xTLR1[tAb] copptby[WB] xTLR2[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12077222(D)
  *** xTLR1[tAb] copptby[WB] xTLR4[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 12077222(D)
  *** xTLR2[tAb] copptby[WB] xTLR1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12077222(D)
  *** TLR3[Ab] cleavage[WB] is detectable
    *** cells: hMDDCs in BMS
    *** source: 22611194-Fig-3b
  *** xTLR3[tAb] cleavage[WB] is detectable
    *** cells: HEK293<xTLR3> in BMS
    *** inhibited by: Leupeptin [addition]
    *** source: 22611194-Fig-2f
  *** xTLR3[tAb] cleavage[WB] is detectable
    *** cells: HEK293<xTLR3> in BMS
    *** inhibited by: Leupeptin [addition]
    *** source: 22611194-Fig-S2b
  *** TLR3[tAb] cleavage[WB] is detectable
    *** cells: hMDDCs in BMS "treated with Ifng for 18 hr"
    *** inhibited by: Leupeptin [addition]
    *** source: 22611194-Fig-S3a
  *** TLR3[tAb] cleavage[WB] is detectable
    *** cells: RPE1 in BMS
    *** source: 22611194-Fig-3a
  *** TLR3[tAb] cleavage[WB] is detectable
    *** cells: RPE1 in BMS "treated with PolyIC for 24 hr"
    *** reqs: Ctsb and/or Ctsh [RNAi]
    *** does not req: CtsL1 [RNAi]
    *** source: 22611194-Fig-6c
  *** TLR3[tAb] prot-exp[WB] is decreased itao Unc93b1 [RNAi]
    *** cells: RPE1 in BMS
    *** source: 22611194-Fig-3e
  *** rTLR4[Ab] boundby[WB] rTirap[Ab] is detectable
    *** cells: none
    *** source: 11526399(D)
  *** TLR4[Ab] copptby[WB] Hgs[Ab] is detectable
    *** cells: hPBMCs in BMS
    *** unaffected by: Lps (1,3 hr) [stim]
    *** source: 16467847-Fig-4b
  *** xTLR4[Ab] snaggedby[WB] rTirap[GST] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: xTLR4(P714H)"CA" [substitution]
    *** source: 12888566-Fig-3d
  *** xTLR4[tAb] colocwith[IHC] xRab5s[XFP] is detectable
    *** cells: mBMMs in BMS
    *** source: 18297073-Fig-1a
  *** xTLR4[tAb] copptby[WB] xTirap[tAb] is detectable
    *** cells: HEK293<xMd2> in BMS
    *** unaffected by: Lps (15 min) [stim]
    *** source: 11544529-Fig-4b
  *** xTLR4[tAb] copptby[WB] xTirap[tAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xTirap(P125H)"DN" [addition]
    *** unaffected by: xTLR4(P714H)"CA" [addition]
    *** source: 11526399(D)
  *** xTLR4[tAb] copptby[WB] xTLR1[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 12077222(D)
  *** xTLR4[XFP] colocwith[IHC] xCd14[Ab] is detectable
    *** cells: HEK293<xTLR4><xCd14> in BMS
    *** source: 12324469(D)
  *** xTLR4[XFP] colocwith[IHC] xMd2[Ab] is detectable
    *** cells: HEK293<xTLR4><xMd2> in BMS
    *** source: 12324469(D)
  *** TLR9-gene promo-reporter[Luc] is decreased itpo xJun
    *** cells: RPMI8226 in BMS
    *** source: 15294971-Fig-7
  *** TLR9-gene promo-reporter[Luc] is decreased itpo xRela
    *** cells: RPMI8226 in BMS
    *** source: 15294971-Fig-7
  *** TLR9-gene promo-reporter[Luc] is decreased itpo xSpi1
    *** cells: RPMI8226 in BMS
    *** source: 15294971-Fig-7
  *** TLR9-gene promo-reporter[Luc] is increased itpo xCebpa
    *** cells: RPMI8226 in BMS
    *** source: 15294971-Fig-7
  *** TLR9-gene promo-reporter[Luc] is increased itpo xCebpb
    *** cells: RPMI8226 in BMS
    *** source: 15294971-Fig-7
  *** TLR9-gene promo-reporter[Luc] is increased itpo xCebpd
    *** cells: RPMI8226 in BMS
    *** source: 15294971-Fig-7
  *** TLR9-gene promo-reporter[Luc] is increased itpo xCebpe
    *** cells: RPMI8226 in BMS
    *** source: 15294971-Fig-7
  *** TLR9-gene promo-reporter[Luc] is increased itpo xCreb1
    *** cells: RPMI8226 in BMS
    *** source: 15294971-Fig-7
  *** TLR9-gene promo-reporter[Luc] is unchanged itpo xAtf2
    *** cells: RPMI8226 in BMS
    *** source: 15294971-Fig-7
  *** TLR9-gene promo-reporter[Luc] is unchanged itpo xCebpg
    *** cells: RPMI8226 in BMS
    *** source: 15294971-Fig-7
  *** TLR9-gene promo-reporter[Luc] is unchanged itpo xElf1
    *** cells: RPMI8226 in BMS
    *** source: 15294971-Fig-7
  *** TLR9-gene promo-reporter[Luc] is unchanged itpo xElk1
    *** cells: RPMI8226 in BMS
    *** source: 15294971-Fig-7
  *** TLR9-gene promo-reporter[Luc] is unchanged itpo xEts1
    *** cells: RPMI8226 in BMS
    *** source: 15294971-Fig-7
  *** TLR9-gene promo-reporter[Luc] is unchanged itpo xEts2
    *** cells: RPMI8226 in BMS
    *** source: 15294971-Fig-7
  *** TLR9-gene promo-reporter[Luc] is unchanged itpo xFos
    *** cells: RPMI8226 in BMS
    *** source: 15294971-Fig-7
  *** TLR9-gene promo-reporter[Luc] is unchanged itpo xSpib
    *** cells: RPMI8226 in BMS
    *** source: 15294971-Fig-7
  *** TLR9-gene promo-reporter[Luc] is unchanged itpo xSpic
    *** cells: RPMI8226 in BMS
    *** source: 15294971-Fig-7
  *** TLR9[Ab] colocwith[IHC] Tf[Fluor] is undetectable
    *** cells: hPDCs in BMS
    *** source: 14716310-Fig-6a
  *** xTLR9[XFP] colocwith[IHC] Canx[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 14716310-Fig-1b
  *** xTLR9[XFP] colocwith[IHC] Canx[Ab] is detectable
    *** cells: hPDCs in BMS
    *** source: 14716310-Fig-1d
  *** xTLR9[XFP] colocwith[IHC] xEea1[XFP] is undetectable
    *** cells: hPDCs in BMS
    *** source: 14716310-Fig-1e
  *** xTLR9[XFP] colocwith[IHC] xTLR4[XFP] is undetectable
    *** cells: HEK293 in BMS
    *** source: 14716310-Fig-1c
  *** xTmem173[tAb] copptby[WB] xDdx41[tAb] is detectable
    *** cells: HEK293T<xDdx41><xTmem173> in BMS
    *** source: 23142775-Fig-S4a
  *** xTmem173[tAb] snaggedby[WB] c-diGMP[biotin] is detectable
    *** cells: HEK293T<xTmem173> in BMS
    *** reqs: Ddx41 [RNAi]
    *** source: 23142775-Fig-7a
  *** Tnf[Ab] secretion[ELISA] is detectable
    *** cells: hPDCs in BMS "treated with CpG-2216 for 48 hr"
    *** partially inhibited by: anti-IfnaR [cotreatment]
    *** source: 12707322-Fig-4d
  *** Tnf[Ab] secretion[ELISA] is detectable
    *** cells: hPDCs in BMS "treated with CpG-2216 for 48 hr"
    *** unaffected by: anti-IfnaR [cotreatment]
    *** source: 12707322-Fig-4d
  *** rTnfaip3 ubiq[tUbAb] is increased by (rUbiq + rUbe1 + rUbe2d1)
    *** cells: none
    *** source: 15258597-Fig-1b,1c
  *** rTnfaip3 ubiq[tUbAb] is increased by (rUbiq + rUbe1 + rUbe2d1)
    *** cells: none
    *** unaffected by: rUbiq(dig)"K48-only" [substitution]
    *** partially inhibited by: rUbiq(K63only) [substitution]
    *** source: 15258597-Fig-2b
  *** Tnfaip3-gene mRNA[RTPCR] is unchanged itao Pias2a [RNAi]
    *** cells: HELA in BMLS
    *** source: 15920481-Fig-1e
  *** xTnfaip3(378-790)"Cterm"[tAb] copptby[WB] xIkke[tAb] is detectable
    *** cells: HEK293<xTnfaip3(378-790)"Cterm"><xIkke> in BMS
    *** inhibited by: xTnfaip3(1-378)"Nterm" [substitution]
    *** source: 15661910-Fig-3f
  *** xTnfaip3(378-790)"Cterm"[tAb] copptby[WB] xTbk1[tAb] is detectable
    *** cells: HEK293<xTnfaip3(378-790)"Cterm"><xTbk1> in BMS
    *** inhibited by: xTnfaip3(1-378)"Nterm" [substitution]
    *** source: 15661910-Fig-3e
  *** Tnfaip3[Ab] copptby[WB] Traf1[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 8692885-Fig-1b
  *** xTnfaip3[Ab] copptby[WB] Ube2d3[Ab] is detectable
    *** cells: mEFs<Tnfaip3~null><xTnfaip3> in BMS "treated with IL1 for 30-60 min"
    *** inhibited by: xTnfaip3(C103A) [substitution]
    *** inhibited by: xTnfaip3(C624A/C627A) [substitution]
    *** source: 20185725-Fig-4e
  *** xTnfaip3[Ab] copptby[WB] xTraf1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 8692885-Fig-1a
  *** xTnfaip3[Ab] copptby[WB] xTraf2[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 8692885-Fig-1a
  *** xTnfaip3[Ab] snaggedby[WB] rTnip2[GST] is detectable
    *** cells: HEK293<xTnfaip3> in BMS
    *** inhibited by: rTnip2(1-250) [substitution]
    *** unaffected by: rTnip2(251-429) [substitution]
    *** source: 15169888-Fig-6b
  *** xTnfaip3[tAb] copptby[WB] xIkke[tAb] is detectable
    *** cells: HEK293<xTnfaip3><xIkke> in BMS
    *** source: 15661910-Fig-3b
  *** xTnfaip3[tAb] copptby[WB] xNemo[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 10755617(D)
  *** xTnfaip3[tAb] copptby[WB] xNod1[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 10329646(D)
  *** xTnfaip3[tAb] copptby[WB] xRnf11[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 19131965-Fig-1a
  *** xTnfaip3[tAb] copptby[WB] xTbk1[tAb] is detectable
    *** cells: HEK293<xTnfaip3><xTbk1> in BMS
    *** source: 15661910-Fig-3a
  *** xTnfaip3[tAb] copptby[WB] xTnfR1[Ab] is detectable
    *** cells: HEK293T in BMS
    *** source: 10755617(D)
  *** xTnfaip3[tAb] copptby[WB] xTrif[tAb] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: xTraf6 [addition]
    *** source: 15474016-Fig-3a
  *** xTnfaip3[tAb]IP ubiq[tUbAb] is increased by (rUbiq + rUbe1 + rCdc34)
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** source: 15258597-Fig-1a
  *** xTnfaip3[tAb]IP ubiq[tUbAb] is increased by (rUbiq + rUbe1 + rUbe2d1)
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** source: 15258597-Fig-1a,1b
  *** xTnfaip3[tAb]IP ubiq[tUbAb] is increased by (rUbiq + rUbe1 + rUbe2l3)
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** source: 15258597-Fig-1a
  *** xTnfaip3[tAb]IP ubiq[tUbAb] is unchanged by (rUbiq + rUbe1 + rUbc13 + rUbe2v2)
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** source: 15258597-Fig-1a
  *** xTnfaip3[tAb]IP ubiq[tUbAb] is unchanged by (rUbiq + rUbe1 + rUbe2c)
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** source: 15258597-Fig-1a
  *** xTnfaip3[tAb]IP ubiq[tUbAb] is unchanged by (rUbiq + rUbe1 + rUbe2d2)
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** source: 15258597-Fig-1a
  *** xTnfaip3[tAb]IP ubiq[tUbAb] is unchanged by (rUbiq + rUbe1 + rUbe2d3)
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** source: 15258597-Fig-1a
  *** xTnfaip3[tAb]IP ubiq[tUbAb] is unchanged by (rUbiq + rUbe1 + rUbe2e1)
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** source: 15258597-Fig-1a
  *** xTnfaip3[tAb]IP ubiq[tUbAb] is unchanged by (rUbiq + rUbe1 + rUbe2h)
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** source: 15258597-Fig-1a
  *** xTnfaip3[tAb]IP ubiq[tUbAb] is unchanged by (rUbiq + rUbe1 + rUbe2k)
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** source: 15258597-Fig-1a
  *** xTnfaip3[tAb]IP ubiq[tUbAb] is unchanged by (rUbiq + rUbe1 + rUbe2m)
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** source: 15258597-Fig-1a
  *** TnfR1[Ab] snaggedby[WB] SNA1[agarose] is decreased itpo xSt6gal1
    *** cells: U937 in BMS
    *** source: 21930713-Fig-5e
  *** TnfR1[Ab] snaggedby[WB] SNA1[agarose] is detectable
    *** cells: U937 in BMS
    *** comment: reversed by treatment of lysates with PNGaseF
    *** source: 21930713-Fig-4b
  *** xTnfR1[tAb] copptby[WB] xNod1[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 10329646(D)
  *** TnfR2[Ab] copptby[WB] xTraf2[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 8702708(D)
  *** xTnfR2[Ab] secretion[ELISA] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xAdam17(474-824)"DN" [addition]
    *** source: 10510344-Fig-5
  *** xTnfR2[Ab] secretion[ELISA] is detectable
    *** cells: HEK293<xTnfR2> in BMS
    *** inhibited by: xAdam17(474-824)"DN" [addition]
    *** source: 10510344-Fig-5
  *** xTnfR2[Ab] snaggedby[WB] rTraf2[GST] is detectable
    *** cells: HEK293 in BMS
    *** source: 8069916-Fig-4
  *** xTnfR2[Ab] surface-exp[FACS] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: xAdam17(474-824)"DN" [addition]
    *** source: 10510344-Table-1
  *** xTnfR2[Ab] surface-exp[FACS] is detectable
    *** cells: HEK293<xTnfR2> in BMS
    *** unaffected by: xAdam17(474-824)"DN" [addition]
    *** source: 10510344-Table-1
  *** TnfR2[Ab]IP prot-exp[WB] is detectable
    *** cells: U937 in BMS
    *** source: 8943045-Fig-2a
  *** TnfR2[Ab]IP prot-exp[WB] is undetectable
    *** cells: HELA in BMS
    *** source: 8943045-Fig-2a
  *** TnfRsf21-gene mRNA[RTPCR] is increased itao Ampka1 [RNAi]
    *** cells: THP1 in BMS
    *** reqs: Ampka1 [RNAi]
    *** source: 22833096-Fig-7b
*** Tnik--
  *** rTnik[35S] boundby[WB] rCtnnb1[GST] is detectable
    *** cells: none
    *** inhibited by: rTnik(1042-1360)"Cterm" [substitution]
    *** unaffected by: rTnik(289-1041)"Intermediate" [substitution]
    *** unaffected by: rTnik(289-1360)"delK" [substitution]
    *** unaffected by: rTnik(1-1041)"delC" [substitution]
    *** source: 19816403-Fig-4c
  *** rTnik[35S] boundby[WB] rTcf7l2[GST] is detectable
    *** cells: none
    *** inhibited by: rTnik(1042-1360)"Cterm" [substitution]
    *** inhibited by: rTnik(289-1041)"Intermediate" [substitution]
    *** inhibited by: rTnik(289-1360)"delK" [substitution]
    *** unaffected by: rTnik(1-1041)"delC" [substitution]
    *** source: 19816403-Fig-4c
  *** Tnik[Ab] boundto(Axin2-gene)[ChIP] is decreased itao Ctnnb1 [RNAi]
    *** cells: LS174T in BMS
    *** source: 19816403-Fig-3c
  *** Tnik[Ab] boundto(Myc-gene)[ChIP] is decreased itao Ctnnb1 [RNAi]
    *** cells: LS174T in BMS
    *** source: 19816403-Fig-3c
  *** Tnik[Ab] copptby[WB] Ctnnb1[Ab] is detectable
    *** cells: DLD1 in BMS
    *** source: 20530691-Fig-1a
  *** Tnik[Ab] copptby[WB] Ctnnb1[Ab] is detectable
    *** cells: HCT116 in BMS
    *** source: 20530691-Fig-1a
  *** xTnik[tAb] IVKA(auto)[32P-ATP] is detectable
    *** cells: HEK293T<xTnik> in BMS
    *** inhibited by: xTnik(R152A/D153A) [substitution]
    *** inhibited by: xTnik(K54A) [substitution]
    *** inhibited by: xTnik(D171A/F172A) [substitution]
    *** source: 19816403-Fig-4d
  *** xTnik[tAb] phos[WBMS] is increased itpo xRap2a
    *** cells: HEK293T<xTnik> in BMS
    *** inhibited by: xTnik(K54R) [substitution]
    *** inhibited by: xTnik(mnr)"delCNH" [substitution]
    *** source: 15342639-Fig-4b
  *** xTnik[tAb] snaggedby[WB] rHras{GTPgS}[GST] is undetectable
    *** cells: HEK293T<xTnik> in BMS
    *** source: 15342639-Fig-1b
  *** xTnik[tAb] snaggedby[WB] rRap1a{GTPgS}[GST] is undetectable
    *** cells: HEK293T<xTnik> in BMS
    *** source: 15342639-Fig-1b
  *** xTnik[tAb] snaggedby[WB] rRap2a{GTPgS}[GST] is detectable
    *** cells: HEK293T<xTnik> in BMS
    *** inhibited by: rRap2a{GDP} [substitution]
    *** inhibited by: rRap2a{NucFree} [substitution]
    *** source: 15342639-Fig-1a
  *** xTnik[tAb] snaggedby[WB] rRap2a{GTPgS}[GST] is detectable
    *** cells: HEK293T<xTnik> in BMS
    *** inhibited by: xTnik(mnr)"delCNH" [substitution]
    *** source: 15342639-Fig-1b
  *** Tnip2-gene mRNA[RTPCR] is detectable
    *** cells: mEFs in BMS
    *** does not req: Nfkb1 [KO]
    *** source: 15169888-Fig-8b
  *** Tnip2-gene mRNA[RTPCR] is unchanged itpo xNfkb1
    *** cells: HEK293<xTnip2> in BMS
    *** source: 15169888-Fig-3a
  *** rTnip2[35S] boundby[WB] rNfkb1(497-968)[GST] is detectable
    *** cells: none
    *** source: 15169888-Fig-5c
  *** Tnip2[Ab] copptby[WB] Nfkb1[Ab] is detectable
    *** cells: HELAS3 in BMS
    *** source: 15169888-Fig-1c
  *** Tnip2[Ab] copptby[WB] Tpl2[Ab] is detectable
    *** cells: HELAS3 in BMS
    *** source: 15169888-Fig-1c
  *** xTnip2[Ab] copptby[WB] xNfkb1(1-433)[tAb] is detectable
    *** cells: HEK293<xTnip2><xNfkb1(1-433)> in BMS
    *** source: 15169888-Fig-2a
  *** xTnip2[Ab] copptby[WB] xNfkb1[tAb] is detectable
    *** cells: HEK293<xTnip2><xNfkb1> in BMS
    *** comment: unaffected by removal of endogenous Tpl2 from lysate
    *** source: 15169888-Fig-2a
  *** xTnip2[Ab] copptby[WB] xNfkb1[tAb] is detectable
    *** cells: HEK293<xTnip2><xNfkb1> in BMS
    *** source: 15169888-Fig-2a
  *** xTnip2[Ab] copptby[WB] xTpl2[tAb] is detectable
    *** cells: HEK293<xTnip2><xTpl2> in BMS
    *** source: 15169888-Fig-2b
  *** Tnip2[Ab] copptby[WB] xTpl2[tAb] is detectable
    *** cells: RAW2647<xTpl2> in BMS
    *** unaffected by: xTpl2(S400A) [substitution]
    *** source: 17709378-Fig-6a
  *** xTnip2[Ab] snaggedby[WB] rTpl2(398-467)[GST] is detectable
    *** cells: HEK293<xTnip2> in BMS
    *** source: 15169888-Fig-5c
  *** Tnip2[Ab]IP prot-exp[WB] is detectable
    *** cells: mBMMs in BMS
    *** reqs: Nfkb1 [KO]
    *** source: 15169888-Fig-8c
  *** Tnip2[Ab]IP prot-exp[WB] is detectable
    *** cells: mEFs in BMS
    *** reqs: Nfkb1 [KO]
    *** source: 15169888-Fig-8a
  *** xTnip2[tAb] prot-exp[WB] is unchanged itpo xNfkb1
    *** cells: HEK293<xTnip2> in BMS
    *** source: 15169888-Fig-3a
  *** xTnk2(K158R)[Ab]IP phos[32P-ATP] is increased by pHck
    *** cells: none
    *** IPfrom: COS7 in BMS
    *** source: 14506255(D)
  *** xTnk2(K158R)[Ab]IP Yphos[pYAb] is increased itpo xHck
    *** cells: COS7 in BMLS
    *** source: 14506255-Fig-8a
  *** xTnk2(Y284F)[Ab]IP phos[32P-ATP] is increased by pHck
    *** cells: none
    *** IPfrom: COS7 in BMS
    *** source: 14506255(D)
  *** Tnk2[Ab] copptby[WB] Clathrin[Ab] is detectable
    *** cells: NEURO2A in BMS
    *** source: 17182860(D)
  *** Tnk2[Ab] copptby[WB] Nck1[Ab] is detectable
    *** cells: HER14 in BMLS
    *** source: 16777958-Fig-3a
  *** xTnk2[Ab] copptby[WB] xNck1[Ab] is detectable
    *** cells: HEK293 in BMLS
    *** inhibited by: xNck1(R308A) [substitution]
    *** inhibited by: xTnk2(K158A) [substitution]
    *** source: 16777958-Fig-3b
  *** xTnk2[Ab] snaggedby[WB] rGrb2[GST] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: rGrb2(P49L) [substitution]
    *** unaffected by: rGrb2(G203R) [substitution]
    *** unaffected by: rGrb2(E89K/S90N) [substitution]
    *** source: 11394904-Fig-1b
  *** xTnk2[Ab]IP phos(Y284)[phosAb] is detectable
    *** cells: HELA in BMS
    *** inhibited by: xTnk2(K158A) [substitution]
    *** inhibited by: xTnk2(H464D) [substitution]
    *** enhanced by: xTnk2(W426K) [substitution]
    *** source: 16777958-Fig-5a
  *** xTnk2[Ab]IP Yphos[pYAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 16777958-Fig-1c
  *** xTnk2[Ab]IP Yphos[pYAb] is detectable
    *** cells: HELA in BMS
    *** inhibited by: xTnk2(K158A) [substitution]
    *** inhibited by: xTnk2(H464D) [substitution]
    *** enhanced by: xTnk2(W426K) [substitution]
    *** source: 16777958-Fig-5a
  *** xTnk2[Ab]IP Yphos[pYAb] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 16777958-Fig-1c
  *** xTnk2[tAb] snaggedby[WB] rUbiq{mono}[GST] is detectable
    *** cells: COS7 in BMS
    *** source: 17182860-Fig-8c
  *** xTnk2[tAb] snaggedby[WB] rUbiq{poly}[GST] is detectable
    *** cells: COS7 in BMS
    *** source: 17182860-Fig-8c
  *** Tns1[Ab] snaggedby[WB] rPak1[GST] is undetectable
    *** cells: 3Y1 in BMS
    *** source: 11096073-Fig-1a
  *** Tns1[Ab] snaggedby[WB] rPak3[GST] is undetectable
    *** cells: 3Y1 in BMS
    *** source: 11096073-Fig-1a
  *** xTns3[tAb]IP Yphos[pYAb] is detectable
    *** cells: HEK293<xSrc(Y529F)"CA"> in BMLS
    *** inhibited by: xSrc(K295L)"DN" [substitution]
    *** source: 15140944-Fig-3e
  *** rTollip[35S] boundby[WB] rTollip[GST] is detectable
    *** cells: none
    *** source: 11751856-Fig-3a
  *** xTollip[tAb] copptby[WB] xTLR2[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 11751856(D)
  *** xTollip[tAb] copptby[WB] xTLR4[tAb] is increased itpo xMd2
    *** cells: HEK293<xTLR4> in BMS
    *** source: 11751856(D)
  *** xTollip[tAb] oligomerization[2TagPpt] is detectable
    *** cells: HEK293 in BMS
    *** source: 11751856-Fig-3b
  *** rTp53 boundby[ELISA] rMdm2[Ab] is detectable
    *** cells: none
    *** comment: inhibited by Mdm2 phos by (xCyclinA2[Ab]IP + xCdk2[Ab]IP)
    *** comment: unaffected by Mdm2(T216A) phosed by (xCyclinA2[Ab]IP + xCdk2[Ab]IP)
    *** source: 11359766-Fig-7a
  *** Tp53 boundto(Bax-gene)[ChIP] is detectable
    *** cells: mEFs in BMS "treated with ActinomycinD for 12 hr"
    *** partially reqs: Pin1 [KO]
    *** source: 12397361-Fig-S3b
  *** Tp53 boundto(Bax-gene)[ChIP] is detectable
    *** cells: mEFs in BMS "treated with Adriamycin for 8 hr"
    *** partially reqs: Pin1 [KO]
    *** source: 12397361-Fig-S3b
  *** Tp53 boundto(Cdkn1a-gene)[ChIP] is detectable
    *** cells: mEFs in BMS "treated with ActinomycinD for 12 hr"
    *** partially reqs: Pin1 [KO]
    *** source: 12397361-Fig-3e
  *** Tp53 boundto(Cdkn1a-gene)[ChIP] is detectable
    *** cells: mEFs in BMS "treated with Adriamycin for 8 hr"
    *** partially reqs: Pin1 [KO]
    *** source: 12397361-Fig-3e
*** Tp53--
  *** Tp53-gene mRNA[RTPCR] is detectable
    *** cells: mEFs in BMS
    *** reqs: Egr1 [KO]
    *** source: 15958557-Fig-1
  *** Tp53-reporter[Luc] is decreased itpo xAkt1(mnr)"CA"
    *** cells: MCF7 in BMS
    *** source: 11504915-Fig-4e
  *** Tp53-reporter[Luc] is decreased itpo xCop1
    *** cells: SAOS2<Tp53~null><xTp53> in BMS
    *** reversed by: xCop1(mnr)"del-ring" [substitution]
    *** source: 15103385-Fig-2h
  *** Tp53-reporter[Luc] is decreased itpo xMdm2
    *** cells: CV1<xTp53> in BMS
    *** inhibited by: xMdm2(S407D) [substitution]
    *** inhibited by: xMdm2(S407D) [substitution]
    *** source: 14654783-Fig-6b
  *** Tp53-reporter[Luc] is decreased itpo xMdm2
    *** cells: H1299<Tp53~null><xTp53> in BMS
    *** enhanced by: xMdm2(Y394F) [substitution]
    *** source: 12110584-Fig-9
  *** Tp53-reporter[Luc] is detectable
    *** cells: U2OS in BMS
    *** reqs: Pin1 [AntiSense]
    *** source: 12397361-Fig-2c
  *** Tp53-reporter[Luc] is increased itao Cop1 [RNAi]
    *** cells: U2OS in BMS
    *** source: 15103385-Fig-4b
  *** Tp53-reporter[Luc] is increased itao Mdm2 [RNAi]
    *** cells: U2OS in BMS
    *** source: 15103385-Fig-4b
  *** Tp53-reporter[Luc] is increased itao Pirh2 [RNAi]
    *** cells: U2OS in BMS
    *** source: 15103385-Fig-4b
  *** Tp53-reporter[Luc] is increased itpo (xTp53 + xPin1)
    *** cells: U2OS in BMS
    *** inhibited by: xTp53(S33A/S315A/T81A) [substitution]
    *** source: 12397361-Fig-2a
  *** Tp53-reporter[Luc] is increased itpo xCbp
    *** cells: H1299<Tp53~null><xTp53> in BMS
    *** enhanced by: xHipk2 [addition]
    *** source: 11740489-Fig-6e
  *** Tp53-reporter[Luc] is increased itpo xCdk5r1{p25}
    *** cells: CHO<xTp53> in BMS
    *** source: 12064478-Fig-4
  *** Tp53-reporter[Luc] is increased itpo xHipk2
    *** cells: H1299<Tp53~null><xTp53> in BMS
    *** enhanced by: xCbp [addition]
    *** source: 11740489-Fig-6e
  *** Tp53-reporter[Luc] is increased itpo xHipk2
    *** cells: H1299<Tp53~null><xTp53> in BMS
    *** inhibited by: xTp53(S46A) [substitution]
    *** source: 11740489-Fig-5c
  *** Tp53-reporter[Luc] is increased itpo xHipk2
    *** cells: HEK293 in BMS
    *** source: 11740489-Fig-4a
  *** Tp53-reporter[Luc] is increased itpo xHipk2
    *** cells: SAOS2<Tp53~null><xTp53> in BMS
    *** inhibited by: xHipk2(K221A) [substitution]
    *** source: 11740489-Fig-4c
  *** Tp53-reporter[Luc] is increased itpo xMekk1(mnr)"CA"
    *** cells: H1299<Tp53~null><xTp53> in BMS
    *** inhibited by: xTp53(T81A) [substitution]
    *** source: 11283254-Fig-4a
  *** Tp53-reporter[Luc] is increased itpo xMkk7(mnr)"CA"
    *** cells: H1299<Tp53~null><xTp53> in BMS
    *** inhibited by: xTp53(T81A) [substitution]
    *** source: 11283254-Fig-4a
  *** Tp53-reporter[Luc] is increased itpo xMkk7(mnr)"CA" 
    *** cells: H1299<Tp53~null><xTp53> in BMS
    *** partially inhibited by: xDusp10 [addition]
    *** source: 11283254-Fig-5c
  *** Tp53-reporter[Luc] is increased itpo xPin1
    *** cells: SAOS2<Tp53~null><xTp53> in BMS
    *** inhibited by: xPin1(W34A) [substitution]
    *** source: 12397361-Fig-S1c
  *** Tp53-reporter[Luc] is increased itpo xPin1
    *** cells: U2OS<xTp53> in BMS
    *** source: 12397361-Fig-S1d
  *** Tp53-reporter[Luc] is increased itpo xTp53
    *** cells: CHO in BMS
    *** repressed by: Nae1 [null-mut]
    *** source: 15242646-Fig-5b
  *** Tp53-reporter[Luc] is increased itpo xTp53
    *** cells: H1299 in BMS
    *** comment: inhibited by substitution of xTp53 fused to Nedd8
    *** source: 17098746-Fig-6b
  *** Tp53-reporter[Luc] is increased itpo xTp53
    *** cells: H1299<Tp53~null><xTp53><xNedd8> in BMS
    *** unaffected by: xTp53(K370R/K372R/K373R) [substitution]
    *** enhanced by: xTp53(K381R/K382R/K386R) [substitution]
    *** enhanced by: xTp53(K370R/K372R/K373R/K381R/K382R/K386R) [substitution]
    *** comment: reporter-activity was normalized to Tp53 protein levels
    *** source: 15242646-Fig-4b
  *** Tp53-reporter[Luc] is increased itpo xTp53
    *** cells: mEFs<Tp53~null> in BMS
    *** inhibited by: xTp53(T81A) [substitution]
    *** source: 11283254-Fig-4b
  *** Tp53-reporter[Luc] is increased itpo xTp53
    *** cells: SAOS2 in BMS
    *** enhanced by: rTp53(S33A) [substitution]
    *** enhanced by: rTp53(S37A) [substitution]
    *** source: 11483158-Fig-2
  *** Tp53-reporter[Luc] is increased itpo xTp53
    *** cells: SAOS2<Tp53~null> in BMS
    *** inhibited by: xTp53(V143A) [substitution]
    *** source: 12654245-Fig-2d
  *** Tp53-reporter[Luc] is increased itpo xTp53
    *** cells: U2OS in BMS
    *** enhanced by: xPin1 [addition]
    *** unaffected by: xPin1(W34A) [addition]
    *** source: 12397361-Fig-2a
  *** rTp53(1-70)[32P] phos[32P-ATP] is increased by xAtm[tAb]IP
    *** cells: none
    *** IPfrom: HEK293T<xAtm> in BMS
    *** inhibited by: xAtm(mnr)"KD" [substitution]
    *** source: 11459832-Fig-4a
  *** rTp53(1-70)[32P] phos[32P-ATP] is increased by xAtr[tAb]IP
    *** cells: none
    *** IPfrom: HEK293T<xAtr> in BMS
    *** inhibited by: xAtr(mnr)"KD" [substitution]
    *** source: 11459832-Fig-4b
  *** rTp53(1-101)[32P] phos[32P-ATP] is increased by xAtr[tAb]IP
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** unaffected by: rTp53((1-101)/S6A) [substitution]
    *** unaffected by: rTp53((1-101)/S9A) [substitution]
    *** inhibited by: rTp53((1-101)/S15A) [substitution]
    *** source: 9733515-Fig-1b
  *** rTp53(323-393)[Ab] upshift[WBMS] is increased by (rSumo1 + rSae1 + rUba2 + rUbe2i)
    *** cells: none
    *** inhibited by: rUbe2i(C93S) [substitution]
    *** inhibited by: rTp53((323-393)/K386M) [substitution]
    *** source: 16857984-Fig-2b
  *** xTp53(dig)"9KR"[Ab] boundto(Cdkn1a-gene)[ChIP] is detectable
    *** cells: H1299<Tp53~null><xTp53(dig)"9KR"> in BMS
    *** partially reqs: Pin1 [RNAi]
    *** source: 17906639-Fig-5b
  *** xTp53(S46A)[Ab] copptby[WB] Ppp1r13l[Ab] is detectable
    *** cells: H1299<Tp53~null><xTp53(S46A)> in BMS "treated with UV for 12 hr"
    *** unaffected by: xPin1 [addition]
    *** source: 17906639-Fig-7c
  *** xTp53(T81A)[Ab] copptby[WB] Ppp1r13l[Ab] is detectable
    *** cells: H1299<Tp53~null><xTp53(T81A)> in BMS "treated with UV for 12 hr"
    *** inhibited by: xPin1 [addition]
    *** source: 17906639-Fig-7c
  *** pTp53[32P] phos[32P-ATP] is increased by (pCdk9 + pCyclinT1)
    *** cells: none
    *** comment: origin (expression method) of proteins is unclear
    *** comment: phos sites were determined to be S33, S315, and S392 by MS
    *** source: 16552184-Fig-1
  *** rTp53[32P] phos[32P-ATP] is increased by (xCdk5[Ab]IP  + xCdk5r1{p25}[Ab]IP)
    *** cells: none
    *** IPfrom: CHO<xCdk5><xCdk5r1{p25}> in BMS
    *** inhibited by: Roscovitine [addition]
    *** source: 12064478-Fig-2
  *** rTp53[32P] phos[32P-ATP] is increased by pDnapk
    *** cells: none
    *** comment: increase requires presence of DNA in the reaction
    *** partially inhibited by: rTp53(S15A) [substitution]
    *** partially inhibited by: rTp53(S37A) [substitution]
    *** inhibited by: rTp53(S37A/S37A) [substitution]
    *** source: 9363941-Fig-2a
  *** rTp53[32P] phos[32P-ATP] is increased by rCsnk1a1
    *** cells: none
    *** source: 9878046-Fig-3c
  *** rTp53[35S] boundby[WB] rMdm4[GST] is detectable
    *** cells: none
    *** comment: inhibited by substitution with xTp53{acetyl(K164/K120/K372/K373/K381/K382)}[Ab]IP
    *** source: 18485870-Fig-5d
  *** rTp53[35S] boundby[WB] rMdm4[GST] is detectable
    *** cells: none
    *** unaffected by: rTp53(K120R/K164R/K370R/K372R/K373R/K381R/K382R/K386R)"8KR" [substitution]
    *** source: 18485870-Fig-S4
  *** rTp53[35S] upshift[WBMS] is unchanged by (rE4f1 + rUbe2i + rUba2 + rSae1 + rSumo1)
    *** cells: none
    *** source: 17110336-Fig-3e
  *** rTp53[35S] upshift[WBMS] is unchanged by (rE4f1 + rUbe2m + rNedd8)
    *** cells: none
    *** comment: not sure if ommision of E1 (rNae1 + rUba3) was a typo or not needed
    *** source: 17110336-Fig-3e
  *** Tp53[Ab] boundto(Pmaip1-gene)[ChIP] is unchanged itpo xE4f1
    *** cells: U2OS in BMS
    *** source: 17110336-Fig-6e
  *** xTp53[Ab] boundto(Tp53i3-gene)[ChIP] is detectable
    *** cells: H1299<Tp53~null><xTp53> in BMS
    *** unaffected by: xMdm2 [addition]
    *** unaffected by: xCbp + xTip60 + xMdm2 [addition]
    *** source: 18485870-Fig-4c
  *** xTp53[Ab] boundto(Tp53i3-gene)[ChIP] is detectable
    *** cells: H1299<Tp53~null><xTp53> in BMS
    *** unaffected by: xTp53(K120R/K164R/K370R/K372R/K373R/K381R/K382R/K386R)"8KR" [substitution]
    *** source: 18485870-Fig-4c
  *** Tp53[Ab] copptby[WB] Mdm2[Ab] is increased itao Pin1 [KO]
    *** cells: mEFs in BMS "treated with UV"
    *** source: 12397362-Fig-3d
  *** xTp53[Ab] copptby[WB] Ppp1r13l[Ab] is detectable
    *** cells: H1299<Tp53~null><xTp53> in BMS "treated with MG132"
    *** does not req: Pin1 [RNAi]
    *** source: 17906639-Fig-7b
  *** xTp53[Ab] copptby[WB] Ppp1r13l[Ab] is detectable
    *** cells: H1299<Tp53~null><xTp53> in BMS "treated with MG132"
    *** enhanced by: xTp53(S46A) [substitution]
    *** unaffected by: xTp53(T81A) [substitution]
    *** source: 17906639-Fig-7a
  *** xTp53[Ab] copptby[WB] Ppp1r13l[Ab] is detectable
    *** cells: H1299<Tp53~null><xTp53> in BMS "treated with UV for 12 hr"
    *** enhanced by: rTp53(S33A/S46A/T81A/S315A) [substitution]
    *** enhanced by: rTp53(S33A/S46A/T81A/S127A/T150A/S315A) [substitution]
    *** source: 17906639-Fig-S7a
  *** xTp53[Ab] copptby[WB] Ppp1r13l[Ab] is detectable
    *** cells: H1299<Tp53~null><xTp53> in BMS "treated with UV for 12 hr"
    *** enhanced by: xTp53(S46A) [substitution]
    *** enhanced by: xTp53(T81A) [substitution]
    *** source: 17906639-Fig-7a
  *** xTp53[Ab] copptby[WB] Ppp1r13l[Ab] is detectable
    *** cells: H1299<Tp53~null><xTp53> in BMS "treated with UV for 12 hr"
    *** inhibited by: xPin1 [addition]
    *** source: 17906639-Fig-7c
  *** xTp53[Ab] copptby[WB] Ppp1r13l[Ab] is detectable
    *** cells: H1299<Tp53~null><xTp53> in BMS "treated with UV for 12 hr"
    *** inhibited by: xPin1 [addition]
    *** unaffected by: xPin1(S67E) [addition]
    *** unaffected by: xPin1(C113A)"CIA" [addition]
    *** source: 17906639-Fig-7d
  *** xTp53[Ab] copptby[WB] Ppp1r13l[Ab] is detectable
    *** cells: H1299<Tp53~null><xTp53> in BMS "treated with UV for 12 hr"
    *** repressed by: Pin1 [RNAi]
    *** source: 17906639-Fig-7b
  *** xTp53[Ab] copptby[WB] Ppp1r13l[Ab] is increased itpo xEp300
    *** cells: H1299<Tp53~null><xTp53> in BMS
    *** inhibited by: xTp53(K319R/K320R/K321R/K370R/K372R/K373R/K381R/K382R/K386R)"9KR" [substitution] 
    *** source: 17906639-Fig-S8a
  *** Tp53[Ab] infraction(cytoplasmic)[WB] is unchanged itao E4f1 [RNAi]
    *** cells: U2OS in BMS
    *** unaffected by: xE4f1(del(41-85)) [substitution]
    *** source: 17110336-Fig-4b
  *** Tp53[Ab] infraction(cytoplasmic)[WB] is unchanged itpo xE4f1
    *** cells: U2OS in BMS
    *** unaffected by: xE4f1(del(41-85)) [substitution]
    *** source: 17110336-Fig-4b
  *** xTp53[Ab] infraction(nuclear)[WB] is detectable
    *** cells: H1299<Tp53~null><xTp53> in BMS
    *** comment: fraction shifts to cytoplasm when xTp53 fused to mono-Ubiq is substituted
    *** source: 14671306-Fig-S3a
  *** xTp53[Ab] locatedin(cytoplasm)[IHC] is increased itpo xCrm1
    *** cells: U2OS<xTp53> in BMS
    *** enhanced by: xMdm2 [addition]
    *** source: 11713287-Fig-7
  *** xTp53[Ab] locatedin(cytoplasm)[IHC] is increased itpo xCrm1
    *** cells: U2OS<xTp53> in BMS
    *** inhibited by: xTp53(mnr)"Mdm2-binding-mut" [substitution]
    *** partially inhibited by: xTp53(K370R/K372R/K373R/K381R/K382R/K386R) [substitution]
    *** source: 11713287-Fig-7
  *** xTp53[Ab] locatedin(cytoplasm)[IHC] is increased itpo xMdm2
    *** cells: H1299<Tp53~null><xTp53> in BMS
    *** source: 14671306-Fig-S2
  *** xTp53[Ab] locatedin(cytoplasm)[IHC] is increased itpo xMdm2
    *** cells: SAOS2<Tp53~null><xTp53> in BMS
    *** inhibited by: xMdm4 [addition]
    *** comment: this works better using xTp53(V143A) to prevent induction of endogenous Mdm2
    *** source: 11606419-Fig-2b
  *** xTp53[Ab] locatedin(cytoplasm)[IHC] is increased itpo xMdm2
    *** cells: U2OS in BMS
    *** inhibited by: xMdm2(S395A) [substitution]
    *** source: 11331603-Fig-7
  *** xTp53[Ab] locatedin(cytoplasm)[IHC] is increased itpo xMdm2
    *** cells: U2OS<xTp53> in BMS
    *** enhanced by: xCrm1 [addition]
    *** source: 11713287-Fig-7
  *** xTp53[Ab] locatedin(cytoplasm)[IHC] is increased itpo xMdm2
    *** cells: U2OS<xTp53> in BMS
    *** inhibited by: xTp53(mnr)"Mdm2-binding-mut" [substitution]
    *** partially inhibited by: xTp53(K370R/K372R/K373R/K381R/K382R/K386R) [substitution]
    *** source: 11713287-Fig-5
  *** xTp53[Ab] locatedin(cytoplasm)[IHC] is increased itpo xMdm2
    *** cells: U2OS<xTp53> in BMS
    *** inhibited by: xTp53(mnr)"Mdm2-binding-mut" [substitution]
    *** partially inhibited by: xTp53(K370R/K372R/K373R/K381R/K382R/K386R) [substitution]
    *** source: 11713287-Fig-7
  *** xTp53[Ab] locatedin(cytoplasm)[IHC] is increased itpo xMdm2
    *** cells: U2OS<xTp53> in BMS
    *** source: 11713287-Fig-4
  *** xTp53[Ab] locatedin(cytoplasm)[IHC] is increased itpo xMdm2
    *** cells: U2OS<xTp53> in BMS
    *** unaffected by: ALLN [addition]
    *** unaffected by: MG132 [addition]
    *** source: 11713287-Fig-6
  *** Tp53[Ab] nedd[NdAb-ppt] is detectable
    *** cells: COS1 in BMS
    *** source: 15242646-Fig-3e
  *** xTp53[Ab] nedd[tNdAb-ppt] is detectable
    *** cells: H1299<Tp53~null><xTp53><xNedd8> in BMS
    *** inhibited by: xTp53(F19A) [substitution]
    *** source: 15242646-Fig-2e
  *** rTp53[Ab] oligo-binding[EMSA] is decreased by rMdm2
    *** cells: none
    *** comment: reversed when rTp53 is pre-phosed with partially-purified Dnapk
    *** source: 9363941-Fig-5
  *** Tp53[Ab] oligo-binding[EMSA] is detectable
    *** cells: mEFs in BMS "treated with Adriamycin for 6 hr"
    *** partially reqs: Pin1 [KO]
    *** source: 12397361-Fig-S3a
  *** rTp53[Ab] oligo-binding[EMSA] is detectable
    *** cells: none
    *** comment: band is shifted itpo rMdm4 [addition]
    *** comment: shift (Mdm4 binding) is inhibited by substitution with xTp53{acetyl(K164/K120/K372/K373/K381/K382)}[Ab]IP
    *** comment: shift (Mdm4 binding) is unaffected by substitution with xTp53(K120R/K164R/K370R/K372R/K373R/K381R/K382R/K386R)"8KR"
    *** source: 18485870-Fig-S11
  *** rTp53[Ab] oligo-binding[EMSA] is detectable
    *** cells: none
    *** comment: unchanged when rTp53 is pre-phosed with partially-purified Dnapk
    *** source: 9363941-Fig-5
  *** rTp53[Ab] oligo-binding[EMSA] is detectable
    *** cells: none
    *** source: 9288740-Fig-5a
  *** rTp53[Ab] oligo-binding[EMSA] is detectable
    *** cells: none
    *** unaffected by: rTp53(S33A/S46A/T81A/S315A) [substitution]
    *** unaffected by: rTp53(S33A/S46A/T81A/S127A/T150A/S315A) [substitution]
    *** inhibited by: rTp53(R175H) [substitution]
    *** source: 17906639-Fig-S3a
  *** xTp53[Ab] prot-exp[WB] is decreased itpo xCop1
    *** cells: H1299<xTp53> in BMS
    *** unaffected by: xCop1(S387A) [substitution]
    *** source: 16931761-Fig-4f
  *** xTp53[Ab] prot-exp[WB] is decreased itpo xCop1
    *** cells: SAOS2<xTp53> in BMS
    *** partially reversed by: xCop1(S387A) [substitution]
    *** reversed by: xCop1(S387D) [substitution]
    *** source: 16931761-Fig-4e
  *** xTp53[Ab] prot-exp[WB] is decreased itpo xMdm2
    *** cells: H1299<Tp53~null><xTp53> in BMS
    *** partially reversed by: xMdm2(S407D) [substitution]
    *** partially reversed by: xMdm2(S407D) [substitution]
    *** source: 14654783-Fig-6a
  *** xTp53[Ab] prot-exp[WB] is decreased itpo xMdm2
    *** cells: mEFs<Tp53~null><Mdm2~null><xTp53> in BMS
    *** enhanced by: xMdm2(Y394F) [substitution]
    *** source: 12110584-Fig-8
  *** Tp53[Ab] prot-exp[WB] is detectable-but unchanged itpo xCdkn2a
    *** cells: U2OS in BMS
    *** source: 9724636-Fig-4
  *** Tp53[Ab] prot-exp[WB] is increased itao Mdm4 [RNAi]
    *** cells: MCF7 in BMS
    *** source: 12963717-Fig-3a
  *** Tp53[Ab] prot-exp[WB] is increased itao Mdm4 [RNAi]
    *** cells: U2OS in BMS
    *** source: 16163388-Fig-4a
  *** Tp53[Ab] prot-exp[WB] is increased itpo xAkt1(mnr)"DN"
    *** cells: NIH3T3 in BMS
    *** source: 11715018-Fig-2d
  *** Tp53[Ab] prot-exp[WB] is increased itpo xCdk5
    *** cells: SHSY5Y in BMS
    *** source: 12064478-Fig-3
  *** Tp53[Ab] prot-exp[WB] is increased itpo xCdk5r1{p25}
    *** cells: SHSY5Y in BMS
    *** source: 12064478-Fig-3
  *** Tp53[Ab] prot-exp[WB] is increased itpo xE1a!Ade05
    *** cells: NIH3T3 in BMS
    *** comment: new Tp53 cannot be snagged by rPin1[GST]
    *** source: 12397362-Fig-1d
  *** Tp53[Ab] prot-exp[WB] is increased itpo xHras(G12V)"CA"
    *** cells: NIH3T3 in BMS
    *** comment: new Tp53 can be snagged by rPin1[GST]
    *** source: 12397362-Fig-1d
  *** Tp53[Ab] prot-exp[WB] is increased itpo xMdm4
    *** cells: MCF7 in BMS
    *** source: 12963717-Fig-2a
  *** xTp53[Ab] prot-exp[WB] is increased itpo xMkk7(mnr)"CA"
    *** cells: H1299<Tp53~null><xTp53> in BMS
    *** inhibited by: xDusp10 [addition]
    *** source: 11283254-Fig-5a
  *** xTp53[Ab] prot-exp[WB] is increased itpo xMkk7(mnr)"CA"
    *** cells: H1299<Tp53~null><xTp53> in BMS
    *** inhibited by: xDusp10 [addition]
    *** source: 11283254-Fig-5b
  *** xTp53[Ab] prot-exp[WB] is increased itpo xP14Arf
    *** cells: HELA<xTp53><xMdm2> in BMS
    *** source: 9529248-Fig-4b
  *** Tp53[Ab] prot-exp[WB] is increased itpo xP14Arf
    *** cells: MCF7 in BMS
    *** reversed by: E6!Hpv16 [addition]
    *** source: 9724636-Fig-7d
  *** Tp53[Ab] prot-exp[WB] is increased itpo xP14Arf
    *** cells: MCF7 in BMS
    *** source: 9724636-Fig-7b
  *** xTp53[Ab] prot-exp[WB] is increased itpo xP14Arf
    *** cells: mEFs<Tp53~null><Mdm2~null><xTp53> in BMS
    *** source: 15989956-Fig-7a
  *** xTp53[Ab] prot-exp[WB] is increased itpo xP14Arf
    *** cells: mEFs<Tp53~null><Mdm2~null><xTp53> in BMS
    *** source: 15989956-Fig-7c
  *** Tp53[Ab] prot-exp[WB] is increased itpo xP14Arf
    *** cells: U2OS in BMS
    *** source: 9724636-Fig-4
  *** Tp53[Ab] prot-exp[WB] is increased itpo xP14Arf
    *** cells: U2OS in BMS
    *** source: 15989956-Fig-S13
  *** xTp53[Ab] prot-exp[WB] is increased itpo xP14Arf
    *** cells: U2OS<xTp53><xMdm2> in BMS
    *** unaffected by: ALLN [addition]
    *** source: 9724636-Fig-6b
  *** xTp53[Ab] prot-exp[WB] is increased itpo xP14Arf
    *** cells: U2OS<xTp53><xMdm2> in BMS
    *** unaffected by: E6!Hpv16 [addition]
    *** source: 9724636-Fig-6d
  *** Tp53[Ab] prot-exp[WB] is unchanged itao Fbxo11 [RNAi]
    *** cells: U2OS in BMS
    *** source: 17098746-Fig-6b
  *** Tp53[Ab] prot-exp[WB] is unchanged itao Mdm4 [RNAi]
    *** cells: MCF7 in BMS
    *** source: 12963717-Fig-2b
  *** Tp53[Ab] prot-exp[WB] is unchanged itpo xErbb2
    *** cells: NIH3T3 in BMS
    *** source: 11715018-Fig-2d
  *** xTp53[Ab] prot-exp[WB] is unchanged itpo xMdm4
    *** cells: H1299<Tp53~null><xTp53> in BMS
    *** source: 11606419-Fig-1a
  *** xTp53[Ab] prot-exp[WB] is unchanged itpo xMdm4
    *** cells: mEFs<Tp53~null><xTp53> in BMS
    *** source: 11606419-Fig-1b
  *** xTp53[Ab] prot-exp[WB] is unchanged itpo xMdm4
    *** cells: SAOS2<Tp53~null><xTp53> in BMS
    *** source: 11606419-Fig-1c
  *** Tp53[Ab] prot-exp[WB] is unchanged itpo xPin1
    *** cells: U2OS in BMS
    *** source: 12397361-Fig-3a
  *** Tp53[Ab] prot-stability[CHX-WB] is decreased itao Pin1 [KO]
    *** cells: mEFs in BMS "treated with UV"
    *** source: 12397362-Fig-3c
  *** Tp53[Ab] snaggedby[WB] rMdm2[GST] is increased itao Pin1 [KO]
    *** cells: mEFs in BMS "treated with UV"
    *** source: 12397362-Fig-3d
  *** xTp53[Ab] sumo[tSuAb-ppt] is unchanged itpo xMdm2
    *** cells: H1299<Tp53~null><xTp53><xSumo1> in BMS
    *** source: 15242646-Fig-3g
  *** xTp53[Ab] ubiq[tUbAb-ppt] is increased itpo (xMdm2 + xMdm4)
    *** cells: mEFs<Tp53~null><xTp53> in BMS
    *** reqs: xMdm4 [omission]
    *** source: 11606419-Fig-1b
  *** xTp53[Ab] ubiq[tUbAb-ppt] is unchanged itpo xMdm4
    *** cells: H1299<Tp53~null><xTp53> in BMS
    *** source: 11606419-Fig-1a
  *** xTp53[Ab] ubiq[tUbAb-ppt] is unchanged itpo xMdm4
    *** cells: mEFs<Tp53~null><xTp53> in BMS
    *** source: 11606419-Fig-1b
  *** xTp53[Ab] ubiq[tUbAb-ppt] is unchanged itpo xMdm4
    *** cells: SAOS2<Tp53~null><xTp53> in BMS
    *** source: 11606419-Fig-1c
  *** Tp53[Ab]IP acetyl(K373)[AcAb] is increased itpo xE4f1
    *** cells: U2OS in BMS
    *** unaffected by: xE4f1(del(41-85)) [substitution]
    *** source: 17110336-Fig-7b
  *** Tp53[Ab]IP nedd[NdAb] is detectable
    *** cells: COS1 in BMS
    *** source: 15242646-Fig-3e
  *** xTp53[Ab]IP phos[32P-ATP] is increased by (rCyclinA? + rCdk2)
    *** cells: none
    *** IPfrom: SF9<xTp53> in BMS
    *** comment: rCyclinA? and rCdk2 were expressed in SF9 cells and purified by chromatograph
    *** source: 9003781-Fig-1c
  *** xTp53[Ab]IP phos[32P-ATP] is increased by (rCyclinE? + rCdk2)
    *** cells: none
    *** IPfrom: SF9<xTp53> in BMS
    *** comment: rCyclinE? and rCdk2 were expressed in SF9 cells and purified by chromatograph
    *** source: 9003781-Fig-1c
  *** xTp53[Ab]IP phos[32P-ATP] is unchanged by (rCyclinD1 + rCdk4)
    *** cells: none
    *** IPfrom: SF9<xTp53> in BMS
    *** comment: rCyclinD1 and rCdk2 were expressed in SF9 cells and purified by chromatograph
    *** source: 9003781-Fig-1c
  *** rTp53[Ab]IP ubiq[tUbAb] is increased by (rCop1 + rUbe2d2 + rUbe1 + rUbiq)
    *** cells: none
    *** inhibited by: rCop1(S387A) [substitution]
    *** source: 16931761-Fig-4d
  *** xTp53[AcAb] acetyl(K373)[AcAb] is detectable
    *** cells: H1299<Tp53~null><xTp53> in BMS
    *** reqs: Pin1 [RNAi]
    *** source: 17906639-Fig-5b
  *** xTp53[AcAb] acetyl(K382)[AcAb] is detectable
    *** cells: H1299<Tp53~null><xTp53> in BMS
    *** reqs: Pin1 [RNAi]
    *** source: 17906639-Fig-5b
  *** Tp53[phosAb] phos(S15)[phosAb] is detectable
    *** cells: HEPG2 in BMLS "plated on collagen"
    *** unaffected by: Gefitinib [cotreatment]
    *** unaffected by: PD325901 [cotreatment]
    *** unaffected by: BMS345541 [cotreatment]
    *** unaffected by: PHA818637 [cotreatment]
    *** unaffected by: ZSTK474 [cotreatment]
    *** source: 19953085-Fig-S1
  *** rTp53[phosAb] phos(S15)[phosAb] is increased by pDnapk
    *** cells: none
    *** comment: DNA is present in the reaction
    *** inhibited by: rTp53(S15A) [substitution]
    *** partially inhibited by: rTp53(S37A) [substitution]
    *** inhibited by: rTp53(S37A/S37A) [substitution]
    *** source: 9363941-Fig-2b
  *** rTp53[phosAb] phos(S15)[phosAb] is unchanged by rAkt1
    *** cells: none
    *** source: 16163388-Fig-8a
  *** rTp53[phosAb] phos(S15)[phosAb] is unchanged by rCsnk1a1
    *** cells: none
    *** source: 16163388-Fig-8a
  *** rTp53[phosAb] phos(S20)[phosAb] is unchanged by Msk1[Ab]IP
    *** cells: none
    *** IPfrom: JB6CL41 in BMLS "treated with UV for 30 min"
    *** source: 11896587-Fig-4c
  *** rTp53[phosAb] phos(S20)[phosAb] is unchanged by rMsk1{act}
    *** cells: none
    *** source: 11896587-Fig-4d
  *** rTp53[phosAb] phos(S20)[phosAb] is unchanged by rRsk2{act}
    *** cells: none
    *** source: 11896587-Fig-4d
  *** xTp53[tAb] copptby[WB] xCop1[tAb] is detectable
    *** cells: H1299<xCop1><xTp53> in BMS "treated with proteosome inhibitor for the last 3 hrs"
    *** partially inhibited by: xCop1(S387A) [substitution]
    *** source: 16931761-Fig-4c
  *** xTp53[tAb] locatedin(cytoplasm)[IHC] is increased itpo xMdm2
    *** cells: U2OS<xTp53> in BMS
    *** partially inhibited by: xMdm2(S407D) [substitution]
    *** unaffected by: xMdm2(S395D) [substitution]
    *** source: 14654783-Fig-5a
  *** xTp53[tAb] locatedin(cytoplasm)[IHC] is increased itpo xMdm2
    *** cells: U2OS<xTp53> in BMS
    *** partially inhibited by: xMdm2(S407D) [substitution]
    *** unaffected by: xMdm2(S407A) [substitution]
    *** source: 14654783-Fig-5b
  *** xTp53[tAb] ubiq[tUbAb-ppt] is increased itpo xCop1
    *** cells: H1299<xTp53> in BMS
    *** enhanced by: xCop1(S387A) [substitution]
    *** inhibited by: xCop1(S387D) [substitution]
    *** source: 16931761-Fig-S17
  *** xTp53[tAb]IP acetyl(K120)[AcAb] is detectable
    *** cells: H1299<Tp53~null><xTp53> in BMS
    *** inhibited by: xTp53(K120R/K164R/K370R/K372R/K373R/K381R/K382R/K386R)"8KR" [substitution]
    *** source: 18485870-Fig-3b
  *** xTp53[tAb]IP acetyl(K120)[AcAb] is increased itpo (xCbp + xTip60)
    *** cells: H1299<Tp53~null><xTp53><xMdm2> in BMS
    *** inhibited by: xTp53(K120R/K164R/K370R/K372R/K373R/K381R/K382R/K386R)"8KR" [substitution]
    *** source: 18485870-Fig-4b
  *** xTp53[tAb]IP acetyl(K164)[AcAb] is detectable
    *** cells: H1299<Tp53~null><xTp53> in BMS
    *** inhibited by: xTp53(K120R/K164R/K370R/K372R/K373R/K381R/K382R/K386R)"8KR" [substitution]
    *** source: 18485870-Fig-3b
  *** xTp53[tAb]IP acetyl(K164)[AcAb] is increased itpo (xCbp + xTip60)
    *** cells: H1299<Tp53~null><xTp53><xMdm2> in BMS
    *** inhibited by: xTp53(K120R/K164R/K370R/K372R/K373R/K381R/K382R/K386R)"8KR" [substitution]
    *** source: 18485870-Fig-4b
  *** xTp53[tAb]IP acetyl(K372/K373/K381/K382)[AcAb] is detectable
    *** cells: H1299<Tp53~null><xTp53> in BMS
    *** inhibited by: xTp53(K120R/K164R/K370R/K372R/K373R/K381R/K382R/K386R)"8KR" [substitution]
    *** source: 18485870-Fig-3b
  *** xTp53[tAb]IP acetyl(K372/K373/K381/K382)[AcAb] is increased itpo (xCbp + xTip60)
    *** cells: H1299<Tp53~null><xTp53><xMdm2> in BMS
    *** inhibited by: xTp53(K120R/K164R/K370R/K372R/K373R/K381R/K382R/K386R)"8KR" [substitution]
    *** source: 18485870-Fig-4b
  *** xTp53[tAb]IP oligo-binding[EMSA] is detectable
    *** cells: none
    *** IPfrom: HEK293<xTp53> in BMS
    *** unaffected by: xTp53(K120R/K164R/K370R/K372R/K373R/K381R/K382R/K386R)"8KR" [substitution]
    *** source: 18485870-Fig-2d
  *** xTp53[tAb]IP phos(S15)[phosAb] is detectable
    *** cells: H1299<Tp53~null><xTp53> in BMS
    *** unaffected by: xTp53(K120R/K164R/K370R/K372R/K373R/K381R/K382R/K386R)"8KR" [substitution]
    *** source: 18485870-Fig-3b
  *** xTp53[XFP] locatedin(cytoplasm)[IHC] is increased itpo xGsk3b
    *** cells: mEFs<Tp53~null><Gsk3b~null><xTp53> in BMS
    *** enhanced by: Tunicamycin [addition]
    *** enhanced by: Thapsigargin [addition]
    *** source: 14744935-Fig-6c
  *** Tp53{acetyl(K382)}[AcAb] boundto(Cdkn1a-gene)[ChIP] is detectable
    *** cells: U2OS in BMS "treated with Etoposide for 12 hr"
    *** partially reqs: Pin1 [RNAi]
    *** source: 17906639-Fig-S5b
*** Tp53aip1--
  *** Tp53aip1-gene mRNA[Northern] is increased itpo xTp53
    *** cells: U373MG in BMS
    *** source: 11030628-Fig-1a
  *** Tp53aip1-gene mRNA[RTPCR] is increased itpo xTp53
    *** cells: H1299<Tp53~null> in BMS
    *** partially inhibited by: xTp53(S46A) [substitution]
    *** partially inhibited by: xTp53(del(46-46)) [substitution]
    *** unaffected by: xTp53(S121F) [substitution]
    *** source: 11030628-Fig-8b
  *** Tp53aip1-gene promo-reporter[Luc] is increased itpo xTp53
    *** cells: SAOS2<Tp53~null> in BMS
    *** partially inhibited by: xTp53(S46A) [substitution]
    *** source: 11030628-Fig-8c
  *** Tp53aip1[Ab] locatedin(mitochondria)[IHC] is detectable
    *** cells: MCF7 in BMS
    *** source: 11030628-Fig-2b
  *** xTp53aip1[tAb] locatedin(mitochondria)[IHC] is detectable
    *** cells: COS7<xTp53aip1> in BMS
    *** source: 11030628-Fig-2a
  *** Tp53bp1[Ab] locatedin(DSBs)[IHC] is detectable
    *** cells: mEFs in BMS
    *** comment: seen at both 5 min and 4 hr post UV
    *** comment: reqs Mdc1 [KO] at 4 hr but not at 5 min
    *** source: 16427009-Fig-6a
  *** Tp53bp1[Ab] locatedin(subnuclear-bodies)[IHC] is detectable
    *** cells: HELA in BMS "treated with IR for 6 hr"
    *** comment: colocates with H2ax{phos(S140)}[phosAb]
    *** reqs: Rnf8 [RNAi]
    *** source: 18001825-Fig-4a
  *** Tp53bp1[Ab] locatedin(subnuclear-bodies)[IHC] is detectable
    *** cells: HELA in BMS "treated with IR for 6 hr"
    *** comment: colocates with H2ax{phos(S140)}[phosAb]
    *** reqs: Rnf8 [RNAi]
    *** source: 18001825-Fig-S4a
  *** Tp53bp1[Ab] locatedin(subnuclear-bodies)[IHC] is detectable
    *** cells: HELA in BMS "treated with IR for 6 hr"
    *** reqs: Ubc13 [RNAi]
    *** source: 18001825-Fig-S5d
  *** Tp53bp1[Ab] locatedin(subnuclear-bodies)[IHC] is detectable
    *** cells: HELA<Rnf8~kd><xRnf8> in BMS "treated with IR for 6 hr"
    *** inhibited by: xRnf8(mnr)"delFHA" [substitution]
    *** inhibited by: xRnf8(mnr)"delRING" [substitution]
    *** source: 18001825-Fig-4c
  *** Tp53bp1[Ab] locatedin(subnuclear-bodies)[IHC] is detectable
    *** cells: HELA<Rnf8~kd><xRnf8> in BMS "treated with IR for 6 hr"
    *** inhibited by: xRnf8(mnr)"delFHA" [substitution]
    *** inhibited by: xRnf8(mnr)"delRING" [substitution]
    *** source: 18001825-Fig-S4f
  *** Tp53bp1[Ab] locatedin(subnuclear-bodies)[IHC] is detectable
    *** cells: mEFs in BMS "treated with IR for 6 hr"
    *** comment: colocates with H2ax{phos(S140)}[phosAb]
    *** reqs: Mdc1 [KO]
    *** source: 18001825-Fig-S4d
  *** Tp53bp1[Ab] locatedin(subnuclear-bodies)[IHC] is detectable
    *** cells: mEFs<Mdc1~null><xMdc1> in BMS "treated with IR for 6 hr"
    *** inhibited by: xMdc1(del(698-768)) [substitution]
    *** source: 18001825-Fig-4b
  *** Tp53bp1[Ab] locatedin(subnuclear-bodies)[IHC] is detectable
    *** cells: mEFs<Mdc1~null><xMdc1> in BMS "treated with IR for tnr"
    *** reqs: xMdc1 [omission]
    *** source: 16427009-Fig-S8
  *** Tp53bp1[Ab] prot-exp[WB] is detectable
    *** cells: HELA in BMS
    *** does not req: Rnf8 [RNAi]
    *** source: 18001825-Fig-S4b
  *** Tp53bp1[Ab] snaggedby[WB] sH2ax(123-143){phos(S140)}[GST] is undetectable
    *** cells: HELA in BMS "nuclear-extracts"
    *** unaffected by: sH2ax(123-143) [substitution]
    *** source: 16377563-Fig-1b
  *** Tp53i3-gene mRNA[RTPCR] is increased itpo xTp53
    *** cells: H1299<Tp53~null> in BMS
    *** unaffected by: xTp53(S46A) [substitution]
    *** unaffected by: xTp53(del(46-46)) [substitution]
    *** inhibited by: xTp53(S121F) [substitution]
    *** source: 11030628-Fig-8b
  *** Tp53i3-gene promo-reporter[Luc] is increased itpo xHipk2
    *** cells: MCF7 in BMS
    *** inhibited by: xHipk2(1-864) [substitution]
    *** source: 11780126-Fig-6e
  *** Tp53i3[Ab] prot-exp[WB] is increased itpo xTp53
    *** cells: H1299<Tp53~null> in BMS
    *** inhibited by: xTp53(K120R/K164R/K370R/K372R/K373R/K381R/K382R/K386R)"8KR" [substitution]
    *** source: 18485870-Fig-3c
  *** Tp53i3[Ab] prot-exp[WB] is increased itpo xTp53
    *** cells: H1299<Tp53~null> in BMS
    *** inhibited by: xTp53(K120R/K164R/K370R/K372R/K373R/K381R/K382R/K386R)"8KR" [substitution]
    *** source: 18485870-Fig-7a
  *** xTp53inp1[tAb] copptby[WB] xPkcd[GST] is detectable
    *** cells: HEK293T<xTp53inp1><xPkcd(mnr)"CA"> in BMS
    *** inhibited by: xPkcd(mnr)"CA" [substitution]
    *** inhibited by: xPkcd(mnr)"RegDomain" [substitution]
    *** source: 16377624-Fig-4a
  *** xTp73[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: U2OS<xTp73> in BMS
    *** source: 11713287-Fig-2b
  *** xTp73[Ab] locatedin(nucleus)[IHC] is unchanged itpo xMdm2
    *** cells: U2OS<xTp73> in BMS
    *** source: 11713287-Fig-4
*** Tpi1--
  *** rTpi1[MS] cleavage[WB] is increased by rCasp1
    *** cells: none
    *** source: 17959595(D)
  *** rTpi1[MS] cleavage[WB] is unchanged by rCasp3
    *** cells: none
    *** source: 17959595(D)
  *** rTpl2 IVKA(Mek1)[32P-ATP] is detectable-but unchanged by PS1145
    *** cells: none
    *** source: 15199157-Fig-3d
*** Tpl2--
  *** Tpl2-gene mRNA[RTPCR] is detectable
    *** cells: HEK293 in BMS
    *** reqs: Tnip2 [RNAi]
    *** source: 15169888-Fig-7b
  *** Tpl2-gene mRNA[RTPCR] is detectable
    *** cells: HELAS3 in BMS
    *** reqs: Tnip2 [RNAi]
    *** source: 15169888-Fig-7a
  *** Tpl2-gene mRNA[RTPCR] is detectable
    *** cells: mBMMs in BMS
    *** does not req: Nfkb1 [KO]
    *** source: 12667451-Fig-3b
  *** Tpl2-gene mRNA[RTPCR] is detectable
    *** cells: mEFs in BMS
    *** does not req: Nfkb1 [KO]
    *** source: 12832462-Fig-6f
  *** Tpl2-gene mRNA[RTPCR] is detectable
    *** cells: mSpCs in BMS
    *** does not req: Nfkb1 [KO]
    *** source: 12667451-Fig-3b
  *** Tpl2-gene mRNA[RTPCR] is increased itpo xTnip2
    *** cells: HEK293<xTpl2> in BMS
    *** source: 15169888-Fig-3b
  *** Tpl2-gene mRNA[RTPCR] is unchanged itpo xTnip2
    *** cells: HEK293<xTpl2> in BMS
    *** source: 15169888-Fig-7b
  *** xTpl2(1-397)"delC"[tAb]IP IVKA(Mek1)(S217/S221)[phosAb] is decreased itpo xNfkb1(497-968)
    *** cells: HEK293<xTpl2(1-397)> in BMS
    *** unaffected by: xNfkb1(801-892) [substitution]
    *** source: 12832462-Fig-8a
  *** xTpl2(1-397)"delC"[tAb]IP IVKA(Mek1)(S217/S221)[phosAb] is unchanged itpo xNfkb1
    *** cells: HEK293<xTpl2(1-397)> in BMS
    *** source: 12832462-Fig-8c
  *** xTpl2(del(424-468)/mnr)"KD"[tAb]IP phos[32Pi] is detectable
    *** cells: HEK293T<xTpl2(del(424-468)/mnr)"KD"> in BMS
    *** enhanced by: xAkt1 [addition]
    *** inhibited by: xAkt1(mnr)"KD" [addition]
    *** source: 12138205-Fig-3b
  *** xTpl2(K167M)[tAb]IP phos[32Pi] is increased itpo xTraf2
    *** cells: HELA in BMS
    *** source: 15670770-Fig-2c
  *** xTpl2(K167M)[tAb]IP phos[32Pi] is increased itpo xTraf6
    *** cells: HELA in BMS
    *** source: 15670770-Fig-2c
  *** xTpl2[Ab] copptby[WB] Ripk1[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 16291755-Fig-2b
  *** Tpl2[Ab] copptby[WB] Tnip2[Ab] is detectable
    *** cells: HELAS3 in BMS
    *** source: 15169888-Fig-1c
  *** Tpl2[Ab] copptby[WB] Tnip2[Ab] is detectable
    *** cells: mBMMs in BMS
    *** source: 15169888-Fig-4a
  *** xTpl2[Ab] copptby[WB] xNfkb1(1-433)[tAb] is undetectable
    *** cells: HEK293<xTpl2><xNfkb1(1-433)> in BMS
    *** source: 12667451-Fig-4c
  *** xTpl2[Ab] copptby[WB] xNfkb1(435-969)"delN"[tAb] is detectable
    *** cells: HEK293<xTpl2><xNfkb1(435-969)> in BMS
    *** source: 12667451-Fig-4c
  *** xTpl2[Ab] copptby[WB] xNfkb1[tAb] is detectable
    *** cells: HEK293<xTpl2><xNfkb1> in BMS
    *** source: 12667451-Fig-4c
  *** xTpl2[Ab] copptby[WB] xNfkb2[tAb] is undetectable
    *** cells: HEK293<xTpl2><xNfkb2> in BMS
    *** source: 12667451-Fig-4c
  *** xTpl2[Ab] copptby[WB] xTnip2[tAb] is detectable
    *** cells: HEK293<xTnip2><xTpl2> in BMS
    *** source: 15169888-Fig-2b
  *** Tpl2[Ab] prot-exp[WB] is detectable
    *** cells: HEK293 in BMS
    *** reqs: Tnip2 [RNAi]
    *** source: 15169888-Fig-7b
  *** Tpl2[Ab] prot-exp[WB] is detectable
    *** cells: HELAS3 in BMS
    *** reqs: Tnip2 [RNAi]
    *** source: 15169888-Fig-7a
  *** Tpl2[Ab] prot-exp[WB] is detectable
    *** cells: mBMMs in BMS
    *** reqs: Nfkb1 [KO]
    *** source: 17709378-Fig-1b
  *** Tpl2[Ab] prot-exp[WB] is detectable
    *** cells: mBMMs<Nfkb1~null><xNfkb> in BMS
    *** reqs: xNfkb1 [omission]
    *** enhanced by: xNfkb1(S927A/S932A) [substitution]
    *** source: 15485931-Fig-4e
  *** Tpl2[Ab] prot-exp[WB] is detectable
    *** cells: mBMMs<Nfkb1~null><xNfkb1> in BMS
    *** reqs: xNfkb1 [omission]
    *** enhanced by: xNfkb1(S921A/S923A/S927A) [substitution]
    *** source: 15199157-Fig-9b
  *** Tpl2[Ab] prot-exp[WB] is detectable
    *** cells: mEFs in BMS
    *** reqs: Nfkb1 [KO]
    *** source: 12832462-Fig-6e
  *** Tpl2[Ab] prot-exp[WB] is detectable
    *** cells: mEFs<Nfkb1~null><xNfkb1> in BMS
    *** reqs: xNfkb1 [omission]
    *** source: 12832462-Fig-6e
  *** xTpl2[Ab] prot-exp[WB] is increased itpo xTnip2
    *** cells: HEK293<xTpl2> in BMS
    *** source: 15169888-Fig-7d
  *** Tpl2[Ab] prot-stability[35S-pulse-chase] is detectable
    *** cells: mBMMs in BMS
    *** does not req: Nfkb1 [KO]
    *** source: 12667451-Fig-3c
  *** Tpl2[Ab] prot-stability[35S-pulse-chase] is detectable
    *** cells: mBMMs in BMS
    *** reqs: Nfkb1 [KO]
    *** source: 12667451-Fig-3c
  *** xTpl2[Ab] snaggedby[WB] rMek1(K207A)[GST] is decreased itpo xNfkb1
    *** cells: HEK293<xTpl2> in BMS
    *** reversed by: xNfkb1(del(801-892))"dDD" [substitution]
    *** source: 12832462-Fig-9b
  *** xTpl2[Ab] snaggedby[WB] rMek1(K207A)[GST] is detectable
    *** cells: HEK293<xTpl2> in BMS
    *** inhibited by: rNfkb1(801-892)"DD" [addition]
    *** source: 12832462-Fig-9c
  *** xTpl2[Ab] snaggedby[WB] rTnip2[GST] is detectable
    *** cells: HEK293<xTpl2> in BMS
    *** unaffected by: rTnip2(1-250) [substitution]
    *** inhibited by: rTnip2(1-89) [substitution]
    *** inhibited by: rTnip2(1-107) [substitution]
    *** inhibited by: rTnip2(1-129) [substitution]
    *** inhibited by: rTnip2(1-193) [substitution]
    *** unaffected by: rTnip2(90-250) [substitution]
    *** unaffected by: rTnip2(130-250) [substitution]
    *** unaffected by: rTnip2(194-250) [substitution]
    *** source: 15169888-Fig-6c
  *** xTpl2[Ab] snaggedby[WB] rTnip2[GST] is detectable
    *** cells: HEK293<xTpl2> in BMS
    *** unaffected by: rTnip2(1-250) [substitution]
    *** inhibited by: rTnip2(251-429) [substitution]
    *** source: 15169888-Fig-6b
  *** xTpl2[Ab] snaggedby[WB] rTnip2[GST] is detectable
    *** cells: HEK293<xTpl2> in BMS
    *** unaffected by: xTpl2(D270A) [substitution]
    *** inhibited by: xTpl2(mnr)"delC" [substitution]
    *** source: 15169888-Fig-5d
  *** xTpl2[Ab] snaggedby[WB] rTnip2[GST] is increased itpo xNfkb1
    *** cells: HEK293<xTpl2> in BMS
    *** source: 15169888-Fig-3c
  *** Tpl2[Ab]IP IVKA(Mek1,Erk2,MBP)[32P-ATP] is increased itpo xTraf2
    *** cells: HEK293 in BMS
    *** source: 16291755-Fig-3e
  *** xTpl2[Ab]IP IVKA(Mek1)[32P-ATP] is decreased itpo xNfkb1
    *** cells: HEK293<xTpl2> in BMS
    *** source: 15169888-Fig-9e
  *** xTpl2[Ab]IP IVKA(Mek1)[32P-ATP] is unchanged itpo xTnip2
    *** cells: HEK293<xTpl2> in BMS
    *** source: 15169888-Fig-9e
  *** Tpl2[Ab]IP prot-exp[WB] is detectable
    *** cells: mBMMs in BMS
    *** reqs: Nfkb1 [KO]
    *** source: 12667451-Fig-2b
  *** Tpl2[Ab]IP prot-exp[WB] is detectable
    *** cells: mBMMs in BMS
    *** reqs: Nfkb1 [KO]
    *** source: 12667451-Fig-2d
  *** Tpl2[Ab]IP prot-exp[WB] is detectable
    *** cells: mBMMs in BMS
    *** reqs: Nfkb1 [KO]
    *** source: 12667451-Fig-3a
  *** Tpl2[Ab]IP prot-exp[WB] is detectable
    *** cells: mBMMs<Nfkb1~null><xNfkb1> in BMS
    *** reqs: xNfkb1 [omission]
    *** source: 12667451-Fig-2d
  *** Tpl2[Ab]IP prot-exp[WB] is detectable
    *** cells: mEFs in BMS
    *** reqs: Nfkb1 [KO]
    *** source: 15169888-Fig-8a
  *** Tpl2[Ab]IP prot-exp[WB] is detectable
    *** cells: mPECs in BMS
    *** reqs: Nfkb1 [KO]
    *** source: 12667451-Fig-3a
  *** Tpl2[Ab]IP prot-exp[WB] is detectable
    *** cells: mSpCs in BMS
    *** reqs: Nfkb1 [KO]
    *** source: 12667451-Fig-3a
  *** xTpl2[Ab]IP prot-stability[35S-pulse-chase] is increased itpo xTnip2
    *** cells: HEK293<xTpl2> in BMS
    *** source: 15169888-Fig-7e
  *** xTpl2[phosAb] phos(S400)[phosAb] is increased itpo xAkt1(mnr)"v"
    *** cells: HEK293<xTpl2> in BMS
    *** inhibited by: xTpl2(S400A) [substitution]
    *** source: 17709378-Fig-3d
  *** xTpl2[phosAb] phos(T290)[phosAb] is detectable
    *** cells: HEK293T<xTpl2> in BMS
    *** partially inhibited by: xTpl2(K167R)"KD" [substitution]
    *** inhibited by: xTpl2(T290A) [substitution]
    *** inhibited by: xTpl2(T290D) [substitution]
    *** inhibited by: xTpl2(T290E) [substitution]
    *** source: 15466476-Fig-6b
  *** xTpl2[phosAb] phos(T290)[phosAb] is detectable
    *** cells: HEK293T<xTpl2> in BMS
    *** partially inhibited by: xTpl2(K167R)"KD" [substitution]
    *** source: 15466476-Fig-7a
  *** xTpl2[phosAb] phos(T290)[phosAb] is detectable
    *** cells: HEK293T<xTpl2> in BMS
    *** unaffected by: HerbimycinA [addition]
    *** unaffected by: PMA [addition]
    *** source: 15466476-Fig-7a
  *** xTpl2[phosAb] phos(T290)[phosAb] is detectable
    *** cells: HEK293T<xTpl2> in BMS
    *** unaffected by: Staurosporine [addition]
    *** enhanced by: PMA [addition]
    *** source: 15466476-Fig-7b
  *** xTpl2[tAb] copptby[WB] Ripk1[Ab] is detectable
    *** cells: HEK293T in BMS
    *** source: 14585994-Fig-4a
  *** xTpl2[tAb] copptby[WB] xAkt1[tAb] is detectable
    *** cells: HEK293T<xTpl2><xAkt1> in BMS
    *** source: 12138205-Fig-2a
  *** xTpl2[tAb] copptby[WB] xAkt1[tAb] is detectable
    *** cells: HEK293T<xTpl2><xAkt1> in BMS
    *** unaffected by: xTpl2(del(424-468)) [substitution]
    *** unaffected by: xTpl2(del(397-468)) [substitution]
    *** source: 12138205-Fig-3a
  *** xTpl2[tAb] copptby[WB] xIkk1[tAb] is detectable
    *** cells: HEK293T<xIkk1><xTpl2> in BMS
    *** enhanced by: xTpl2(S400A) [substitution]
    *** unaffected by: xTpl2(del(424-468)) [substitution]
    *** enhanced by: xTpl2(del(424-468)/S400A) [substitution]
    *** source: 12138205-Fig-6c
  *** xTpl2[tAb] copptby[WB] xTab2[tAb] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xTpl2(K167M) [substitution]
    *** source: 15670770-Fig-3c
  *** xTpl2[tAb] copptby[WB] xTnip2[tAb] is detectable
    *** cells: HEK293<xTnip2><xTpl2> in BMS
    *** comment: unaffected by removal of endogenous Nfkb1 from lysate
    *** source: 15169888-Fig-2b
  *** xTpl2[tAb] prot-exp[WB] is increased itpo xNfkb1
    *** cells: HEK293<xTpl2> in BMS
    *** source: 12832462-Fig-6a
  *** xTpl2[tAb] prot-exp[WB] is increased itpo xTnip2
    *** cells: HEK293<xTpl2> in BMS
    *** source: 15169888-Fig-3b
  *** xTpl2[tAb] prot-exp[WB] is unchanged itpo xNfkb1
    *** cells: HEK293<xTpl2> in BMS
    *** source: 15169888-Fig-3c
  *** xTpl2[tAb] prot-exp[WB] is unchanged itpo xNfkb2
    *** cells: HEK293<xTpl2> in BMS
    *** source: 12832462-Fig-6a
  *** xTpl2[tAb] prot-stability[35S-pulse-chase] is increased itpo xNfkb1
    *** cells: HEK293<xTpl2> in BMS
    *** partially inhibited by: xNfkb1(435-969)"delN" [substitution]
    *** source: 12667451-Fig-4a
  *** xTpl2[tAb] prot-stability[35S-pulse-chase] is increased itpo xNfkb1
    *** cells: HEK293<xTpl2> in BMS
    *** source: 12832462-Fig-6b
  *** xTpl2[tAb] prot-stability[35S-pulse-chase] is unchanged itpo xNfkb1(1-433)
    *** cells: HEK293<xTpl2> in BMS
    *** source: 12667451-Fig-4a
  *** xTpl2[tAb] prot-stability[35S-pulse-chase] is unchanged itpo xNfkb2
    *** cells: HEK293<xTpl2> in BMS
    *** source: 12667451-Fig-4a
  *** xTpl2[tAb] snaggedby[WB] rTnip2(1-250)[GST] is detectable
    *** cells: HEK293<xTpl2> in BMS
    *** unaffected by: xTpl2(S400A) [substitution]
    *** source: 17709378-Fig-6a
  *** xTpl2[tAb]IP IVKA(auto)[32P-ATP] is detectable
    *** cells: HEK293T<xTpl2> in BMS
    *** inhibited by: xTpl2(K167R)"KD" [substitution]
    *** inhibited by: xTpl2(T290A) [substitution]
    *** inhibited by: xTpl2(T290D) [substitution]
    *** inhibited by: xTpl2(T290E) [substitution]
    *** source: 15466476-Fig-4b
  *** xTpl2[tAb]IP IVKA(HistH2B)[32P-ATP] is detectable
    *** cells: HEK293T<xTpl2> in BMS
    *** enhanced by: xTpl2(del(424-468)) [substitution]
    *** unaffected by: xTpl2(del(397-468)) [substitution]
    *** unaffected by: xTpl2(S400A) [substitution]
    *** unaffected by: xTpl2(S413A) [substitution]
    *** unaffected by: xTpl2(S400A/S413A) [substitution]
    *** source: 12138205-Fig-5a
  *** xTpl2[tAb]IP IVKA(MBP)[32P-ATP] is detectable-but unchanged itpo xNfkb1
    *** cells: HEK293<xTpl2> in BMS
    *** source: 17709378-Fig-1a
  *** xTpl2[tAb]IP IVKA(Mek1)(S217/S221)[phosAb] is decreased itpo xNfkb1
    *** cells: HEK293<xTpl2> in BMS
    *** reversed by: xNfkb1(del(801-892))"dDD" [substitution]
    *** reversed by: xNfkb1(del(497-538)) [substitution]
    *** source: 12832462-Fig-8c
  *** xTpl2[tAb]IP IVKA(Mek1)(S217/S221)[phosAb] is decreased itpo xNfkb1
    *** cells: HEK293<xTpl2> in BMS
    *** reversed by: xTpl2(1-397)"delC" [substitution]
    *** source: 12832462-Fig-8d
  *** xTpl2[tAb]IP IVKA(Mek1)(S217/S221)[phosAb] is decreased itpo xNfkb1
    *** cells: HEK293<xTpl2> in BMS
    *** source: 17709378-Fig-1a
  *** xTpl2[tAb]IP IVKA(Mek1)(S217/S221)[phosAb] is decreased itpo xNfkb1(497-968)
    *** cells: HEK293<xTpl2> in BMS
    *** partially reversed by: xNfkb1(801-892) [substitution]
    *** source: 12832462-Fig-7b
  *** xTpl2[tAb]IP IVKA(Mek1)(S217/S221)[phosAb] is decreased itpo xNfkb1(497-968)
    *** cells: HEK293<xTpl2> in BMS
    *** reversed by: xNfkb1(497-801/892-968) [substitution]
    *** source: 12832462-Fig-7a
  *** xTpl2[tAb]IP IVKA(Mek1)[32P-ATP] is decreased itpo Nfkb1
    *** cells: HEK293<xTpl2> in BMS
    *** source: 12667451-Fig-6c
  *** xTpl2[tAb]IP IVKA(Mek1)[32P-ATP] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xTpl2(K167M)"KD" [substitution]
    *** inhibited by: xTpl2(T290A) [substitution]
    *** partially inhibited by: xTpl2(T290D) [substitution]
    *** source: 15778223-Fig-2d
  *** xTpl2[tAb]IP IVKA(Mek1)[32P-ATP] is detectable
    *** cells: mEFs in BMS
    *** inhibited by: xTpl2(K167M)"KD" [substitution]
    *** source: 15833743-Fig-3a
  *** xTpl2[tAb]IP IVKA(Mek1)[32P-ATP] is detectable
    *** cells: mEFs in BMS
    *** reqs: Traf2 [KO]
    *** source: 15833743-Fig-3a
  *** xTpl2[tAb]IP IVKA(Mek1)[32P-ATP] is unchanged itpo Nfkb2
    *** cells: HEK293<xTpl2> in BMS
    *** source: 12667451-Fig-6c
  *** xTpl2[tAb]IP phos(T290)[phosAb] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xTpl2(T290A) [substitution]
    *** inhibited by: PS1145 [addition]
    *** source: 15778223-Fig-6b
  *** xTpl2[tAb]IP phos(T290)[phosAb] is detectable
    *** cells: HEK293<xTpl2> in BMS
    *** source: 15699325-Fig-1a
  *** xTpl2[tAb]IP phos(T290)[phosAb] is detectable
    *** cells: HEK293<xTpl2> in BMS
    *** source: 15699325-Fig-1b
  *** xTpl2[tAb]IP prot-exp[WB] is increased itpo xNfkb1
    *** cells: HEK293<xTpl2> in BMS
    *** source: 12667451-Fig-4b
  *** xTpl2[tAb]IP prot-exp[WB] is unchanged itpo xNfkb1(1-433)
    *** cells: HEK293<xTpl2> in BMS
    *** source: 12667451-Fig-4b
  *** xTpl2[tAb]IP prot-exp[WB] is unchanged itpo xNfkb2
    *** cells: HEK293<xTpl2> in BMS
    *** source: 12667451-Fig-4b
  *** Tpl2p52[Ab] copptby[WB] Nfkb1[Ab] is detectable
    *** cells: mBMMs in BMS
    *** source: 12667451-Fig-6b
  *** xTpl2p52[tAb] copptby[WB] xTpl2p58[tAb] is detectable
    *** cells: HEK293<xTpl2p58><xTpl2p52> in BMS
    *** source: 15699325-Fig-1c
  *** Tpl2p58[Ab] copptby[WB] Nfkb1[Ab] is detectable
    *** cells: mBMMs in BMS
    *** source: 12667451-Fig-6b
  *** xTpl2p58[tAb] copptby[WB] xTpl2p52[tAb] is detectable
    *** cells: HEK293<xTpl2p58><xTpl2p52> in BMS
    *** source: 15699325-Fig-1c
  *** xTpl2p58[tAb]IP phos(T290)[phosAb] is increased itpo xTpl2p52
    *** cells: HEK293<xTpl2p58> in BMS
    *** source: 15699325-Fig-1b
  *** xTpl2p58[tAb]IP phos(T290)[phosAb] is increased itpo xTpl2p52
    *** cells: HEK293<xTpl2p58> in BMS
    *** unaffected by: xTpl2p52(T290A) [substitution]
    *** unaffected by: xTpl2p52(T290D) [substitution]
    *** source: 15699325-Fig-1d
*** Tradd--
*** Traf1--
  *** rTraf1[35S] cleavage[WB] is increased by rCasp3
    *** cells: none
    *** source: 10692572-Fig-2a
  *** rTraf1[35S] cleavage[WB] is increased by rCasp6
    *** cells: none
    *** source: 10692572-Fig-2a
  *** rTraf1[35S] cleavage[WB] is increased by rCasp8
    *** cells: none
    *** source: 10692572-Fig-2a
  *** rTraf1[35S] cleavage[WB] is unchanged by rCasp7
    *** cells: none
    *** source: 10692572-Fig-2a
  *** rTraf1[35S] upshift[WBMS] is unchanged by (rCiap2 + rUbe2d2 + rUbe1 + rUbiq)
    *** cells: none
    *** source: 11907583-Fig-2b
  *** rTraf1[35S] upshift[WBMS] is unchanged by (rXiap + rUbe2d2 + rUbe1 + rUbiq)
    *** cells: none
    *** source: 11907583-Fig-2b
  *** Traf1[Ab] copptby[WB] Casp8[Ab] is detectable
    *** cells: HT1080 in BMS
    *** unaffected by: Tnf (16 hr) [stim]
    *** inhibited by: xIkba(mnr)"degradation-deficient-mut" [addition]
    *** source: 12887920(D)
  *** xTraf1[tAb] cleavage[WB] is increased itpo xBak1
    *** cells: HEK293T in BMS
    *** source: 10692572-Fig-1a
  *** xTraf1[tAb] cleavage[WB] is increased itpo xFasR
    *** cells: HEK293T in BMS
    *** source: 10692572-Fig-1a
  *** xTraf1[tAb] cleavage[WB] is increased itpo xRipk1
    *** cells: HEK293T in BMS
    *** source: 10692572-Fig-1a
  *** xTraf1[tAb] cleavage[WB] is increased itpo xTnfRsf25
    *** cells: HEK293T in BMS
    *** source: 10692572-Fig-1a
  *** xTraf1[tAb] cleavage[WB] is increased itpo xTradd
    *** cells: HEK293T in BMS
    *** source: 10692572-Fig-1a
  *** xTraf1[tAb] cleavage[WB] is increased itpo xTrailR1
    *** cells: HEK293T in BMS
    *** source: 10692572-Fig-1a
  *** xTraf1[tAb] copptby[WB] xNik[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 15084608-Fig-1a
  *** xTraf1[tAb] copptby[WB] xNod1[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 10329646(D)
  *** xTraf1[tAb] copptby[WB] xTnfR1[Ab] is increased itpo xTradd
    *** cells: HEK293 in BMS
    *** inhibited by: xTraf2 [addition]
    *** source: 8565075-Fig-5a
  *** xTraf1[tAb] copptby[WB] xTraf2[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 8702708(D)
*** Traf2--
  *** xTraf2[Ab] copptby[WB] xCd40[tAb]IP is detectable
    *** cells: HEK293T<xCd40><xTraf2> in BMS
    *** unaffected by: xCd40(E239A) [substitution]
    *** inhibited by: xCd40(Q253A) [substitution]
    *** inhibited by: xCd40(Q253A/E239A) [substitution]
    *** source: 12370254-Fig-2a
  *** Traf2[Ab] copptby[WB] xTnik[tAb] is detectable
    *** cells: HEK293T<xTnik> in BMS
    *** inhibited by: xTnik(1-306)"N1" [substitution]
    *** unaffected by: xTnik(1-1017)"N2" [substitution]
    *** unaffected by: xTnik(306-1360)"C1" [substitution]
    *** inhibited by: xTnik(1017-1360)"C2" [substitution]
    *** unaffected by: xTnik(306-1017)"M" [substitution]
    *** source: 10521462-Fig-3c
  *** Traf2[Ab] copptby[WB] xTnik[tAb] is detectable
    *** cells: HEK293T<xTnik> in BMS
    *** source: 10521462-Fig-3a
  *** xTraf2[Ab] copptby[WB] xTraf5[tAb] is undetectable
    *** cells: SF21 in BMS
    *** source: 9718306-Fig-3a
  *** xTraf2[Ab] infraction(DRM)[WB] is decreased itpo xTraf1
    *** cells: HEK293T in BMS "treated with Tnf for 6 hr"
    *** source: 12370254-Fig-1a
  *** xTraf2[Ab] infraction(DRM)[WB] is decreased itpo xTraf1
    *** cells: HEK293T<xCd40> in BMS
    *** source: 12370254-Fig-1a
  *** Traf2[Ab] locatedin(cytoplasm)[IHC] is detectable
    *** cells: hUVECs in BMS
    *** source: 11714736-Fig-5c
  *** Traf2[Ab] prot-exp[WB] is unchanged itao Traf2 [KO]
    *** cells: mEFs in BMS
    *** source: 18997792-Fig-S5a
  *** xTraf2[Ab] snaggedby[WB] rCd40[GST] is detectable
    *** cells: M12<xTraf2> in BMS
    *** unaffected by: rCd40(del(230-247))"dTR6" [substitution]
    *** inhibited by: rCd40(del(230-247)/T255A)"dTRs" [substitution]
    *** inhibited by: rCd40(T255A)"dTR23" [substitution]
    *** source: 12354380-Fig-1b
  *** xTraf2[tAb] copptby[WB] xTnik[tAb] is detectable
    *** cells: HEK293T<xTnik><xTraf2> in BMS
    *** inhibited by: xTraf2(1-272) [substitution]
    *** unaffected by: xTraf2(87-501) [substitution]
    *** unaffected by: xTraf2(272-501) [substitution]
    *** source: 10521462-Fig-3e
  *** xTraf2[tAb] prot-exp[WB] is decreased itpo xCiap1
    *** cells: HEK293 in BMS
    *** reversed by: Lactacystin [addition]
    *** source: 11907583-Fig-3f
  *** xTraf2[tAb] prot-exp[WB] is decreased itpo xCiap1
    *** cells: HEK293 in BMS
    *** reversed by: xCiap1(mnr)"E3-activity-mut" [substitution]
    *** source: 11907583-Fig-3c
  *** xTraf2[tAb] prot-exp[WB] is decreased itpo xCiap1
    *** cells: HEK293 in BMS
    *** source: 11907583-Fig-3d
  *** xTraf2[tAb] prot-exp[WB] is decreased itpo xCiap2
    *** cells: HEK293T<xCd40><xTraf2> in BMS
    *** reversed by: MG132 [addition]
    *** source: 18997792-Fig-S6
  *** xTraf2[tAb] prot-exp[WB] is decreased itpo xSiah2
    *** cells: HELA in BMS
    *** source: 14713952-Fig-3a
  *** xTraf2[tAb] prot-exp[WB] is unchanged itpo xUbc13
    *** cells: HELA in BMS
    *** unaffected by: xUbc13(C87A) [substitution]
    *** source: 14713952-Fig-3a
  *** xTraf2[tAb]IP upshift[WBMS] is increased itpo xIkke
    *** cells: HEK293<xTraf2> in BMS
    *** inhibited by: xIkke(K38A) [substitution]
    *** source: 10759890-Fig-7b
  *** xTraf2[XFP] locatedin(cytoplasm)[IHC] is detectable
    *** cells: M1241 in BMS
    *** source: 10748139-Fig-1
*** Traf3--
  *** xTraf3[35S] copptby[WB] xCd40[Ab] is detectable
    *** cells: HEK293T<xTraf3><xCd40> in BMS
    *** source: 7527023-Fig-3a
  *** xTraf3[Ab] copptby[WB] xTank[tAb] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xTradd [addition]
    *** source: 18439848-Fig-3c
  *** Traf3[Ab] copptby[WB] xTradd[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 18439848-Fig-3d
  *** xTraf3[Ab] copptby[WB] xTraf5[tAb] is detectable
    *** cells: SF21 in BMS
    *** source: 9718306-Fig-3a
  *** Traf3[Ab] infraction(nuclear)[WB] is detectable
    *** cells: hMVECs in BMS
    *** source: 11714736-Fig-5d
  *** Traf3[Ab] infraction(nuclear)[WB] is detectable
    *** cells: hUVECs in BMS
    *** unaffected by: Cd40L (6 hr) [stim]
    *** source: 11714736-Fig-5d
  *** Traf3[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: hUVECs in BMS
    *** unaffected by: Cd40L (6 hr) [stim]
    *** source: 11714736-Fig-5c
  *** Traf3[Ab] prot-exp[WB] is increased itao Traf2 [KO]
    *** cells: mEFs in BMS
    *** source: 18997792-Fig-S5a
  *** Traf3[Ab] snaggedby[WB] rCd40(216-277)[GST] is detectable
    *** cells: HELA in BMS
    *** inhibited by: rCd40((216-277)/T254A)"mT2/T3" [substitution]
    *** inhibited by: rCd40((216-277)/Q234A/E235A/Q263A/T254A)"mT2/T3/T6" [substitution]
    *** unaffected by: rCd40((216-277)/Q234A/E235A)"mT6" [substitution]
    *** inhibited by: rCd40((216-277)/Q234A/E235A/Q263A)"mT3/T6" [substitution]
    *** source: 16260598-Fig-1b
  *** Traf3[Ab] snaggedby[WB] rCd40(216-277)[GST] is detectable
    *** cells: mEFs in BMS
    *** does not req: Traf2 [KO]
    *** source: 16260598-Fig-S1
  *** xTraf3[Ab] snaggedby[WB] rCd40[GST] is detectable
    *** cells: M12<xTraf2> in BMS
    *** unaffected by: rCd40(del(230-247))"dTR6" [substitution]
    *** inhibited by: rCd40(del(230-247)/T255A)"dTRs" [substitution]
    *** inhibited by: rCd40(T255A)"dTR23" [substitution]
    *** source: 12354380-Fig-1b
  *** Traf3[Ab] snaggedby[WB] rMyd88[GST] is detectable
    *** cells: RAW2647 in BMS
    *** does not req: Traf6 [RNAi]
    *** source: 19898473-Fig-S3b
  *** Traf3[Ab] snaggedby[WB] rTrif[GST] is detectable
    *** cells: RAW2647 in BMS
    *** does not req: Traf6 [RNAi]
    *** source: 19898473-Fig-S3b
  *** rTraf3[GST] ubiq[UbAb] is increased by (rUbiq + rUbe1 + Ube2h + Cdc34 + Ube2d1 + Ube2d2 + Ube2d3 + Ube2e1 + Ube2l3 + Ube2c + xCiap1[tAb]IP)
    *** cells: none
    *** IPfrom: KMS28BM<Ciap1~null><Ciap2~null><xCiap1> in BMS
    *** inhibited by: xCiap2(mnr)"E3-ligase-inactive"[tAb]IP [substitution]
    *** source: 18635759-Fig-7c
  *** rTraf3[GST]IP ubiq[UbAb] is increased by (Ciap1[tAb]IP + Ciap2[tAb]IP + rUbe1 + rUbe2h + rCdc34 + rUbe2d1 + rUbe2d2 + rUbe2d3 + rUbe2e1 + rUbe2l3 + rUbe2c)
    *** cells: none
    *** IPfrom: A20 in BMS
    *** comment: enhanced by pretreatment of A20 with anti-Cd40 for 1 hr
    *** source: 18997792-Fig-6c
  *** rTraf3[GST]IP ubiq[UbAb] is increased by (Ciap1[tAb]IP + Ciap2[tAb]IP + rUbe1 + rUbe2h + rCdc34 + rUbe2d1 + rUbe2d2 + rUbe2d3 + rUbe2e1 + rUbe2l3 + rUbe2c)
    *** cells: none
    *** IPfrom: A20 in BMS
    *** does not req: Traf3 [RNAi]
    *** source: 18997792-Fig-6c
  *** rTraf3[GST]IP ubiq[UbAb] is increased by (Ciap1[tAb]IP + Ciap2[tAb]IP + rUbe1 + rUbe2h + rCdc34 + rUbe2d1 + rUbe2d2 + rUbe2d3 + rUbe2e1 + rUbe2l3 + rUbe2c)
    *** cells: none
    *** IPfrom: A20 in BMS
    *** reqs: Traf2 [RNAi]
    *** source: 18997792-Fig-6c
  *** rTraf3[GST]IP ubiq[UbAb] is increased by (xTraf2[tAb]IP + xCiap2[tAb]IP + rUbe1 + rUbe2h + rCdc34 + rUbe2d1 + rUbe2d2 + rUbe2d3 + rUbe2e1 + rUbe2l3 + rUbe2c)
    *** cells: none
    *** IP1from: HEK293T<xTraf2> in BMS
    *** IP2from: HEK293T<xCiap2> in BMS
    *** inhibited by: xCiap2(mnr)"RingFingerMutant" [substitution]
    *** comment: enhanced by pretreatment of Hek293T<xTraf2> and Hek293T<xCiap2> with anti-Cd40 for 2 hr
    *** source: 18997792-Fig-6b
  *** rTraf3[tAb] boundby[WB] rNik[Ab] is detectable
    *** cells: none
    *** source: 15084608-Fig-1b
  *** xTraf3[tAb] copptby[WB] xNik[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 15084608-Fig-1a
  *** xTraf3[tAb] prot-exp[WB] is decreased itpo xCiap1
    *** cells: HEK293T<xTraf3> in BMS
    *** source: 18997792-Fig-6a
  *** xTraf3[tAb] prot-exp[WB] is decreased itpo xCiap2
    *** cells: HEK293T<xTraf3> in BMS
    *** source: 18997792-Fig-6a
  *** Traf5[Ab] locatedin(cytoplasm)[IHC] is detectable
    *** cells: hUVECs in BMS
    *** source: 11714736-Fig-5c
  *** xTraf5[tAb] copptby[WB] xNod1[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 10329646(D)
  *** xTraf5[tAb] copptby[WB] xRipk1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 11479302-Fig-3
  *** xTraf5[tAb] copptby[WB] xTak1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xSmad7 [addition]
    *** source: 17384642-Fig-S7b
  *** xTraf5[tAb] copptby[WB] xTradd[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 11479302-Fig-3
  *** xTraf5[tAb] upshift[WBMS] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xUsp21 [addition]
    *** unaffected by: xUsp21(C221A)"CIA" [addition]
    *** source: 19910467-Fig-S2
*** Traf6--
  *** Traf6-gene mRNA[Northern] is detectable
    *** cells: mSpCs in BMS "activated with anti-Cd3 for 48 hr"
    *** does not req: Stat4 [KO]
    *** source: 11120802-Fig-4a
  *** Traf6[Ab] copptby[WB] Ikk1[Ab] is increased itpo xTab2
    *** cells: HEK293 in BMS
    *** source: 15836773-Fig-5a
  *** Traf6[Ab] copptby[WB] Tab2[Ab] is increased itpo xIrak1
    *** cells: HEK293<xIL1R1> in BMS
    *** source: 11259596-Fig-7b
  *** xTraf6[Ab] copptby[WB] xCd40[tAb]IP is detectable
    *** cells: HEK293T<xCd40><xTraf6> in BMS
    *** inhibited by: xCd40(E239A) [substitution]
    *** unaffected by: xCd40(Q253A) [substitution]
    *** inhibited by: xCd40(Q253A/E239A) [substitution]
    *** source: 12370254-Fig-2a
  *** xTraf6[Ab] copptby[WB] xTraf5[tAb] is undetectable
    *** cells: SF21 in BMS
    *** source: 9718306-Fig-3a
  *** Traf6[Ab] snaggedby[WB] rCd40(216-277)[GST] is detectable
    *** cells: HELA in BMS
    *** unaffected by: rCd40((216-277)/T254A)"mT2/T3" [substitution]
    *** inhibited by: rCd40((216-277)/Q234A/E235A/Q263A/T254A)"mT2/T3/T6" [substitution]
    *** inhibited by: rCd40((216-277)/Q234A/E235A)"mT6" [substitution]
    *** inhibited by: rCd40((216-277)/Q234A/E235A/Q263A)"mT3/T6" [substitution]
    *** source: 16260598-Fig-1b
  *** xTraf6[Ab] snaggedby[WB] rCd40[GST] is undetectable
    *** cells: M12<xTraf2> in BMS
    *** source: 12354380-Fig-1b
  *** Traf6[Ab] snaggedby[WB] rMyd88[GST] is detectable
    *** cells: RAW2647 in BMS
    *** does not req: Traf3 [RNAi]
    *** source: 19898473-Fig-S3b
  *** Traf6[Ab] snaggedby[WB] rTrif[GST] is detectable
    *** cells: RAW2647 in BMS
    *** does not req: Traf3 [RNAi]
    *** source: 19898473-Fig-S3b
  *** Traf6[Ab] upshift[WBMS] is increased itpo xIrak1
    *** cells: RAW2647 in BMS
    *** partially reqs: Malt1 [RNAi]
    *** source: 16831874-Fig-9b
  *** Traf6[Ab]IP ubiq[tUbAb] is increased itpo xTab2
    *** cells: HEK293<xUbiq> in BMS
    *** source: 15836773-Fig-2
  *** Traf6[Ab]IP ubiq[UbAb] is decreased itpo xTnfaip3
    *** cells: mEFs in BMS "treated with Lps for tnr"
    *** reqs: Rnf11 [RNAi]
    *** source: 19131965-Fig-5e
  *** xTraf6[tAb] copptby[WB] Traf2[Ab] is detectable
    *** cells: HEK293<xCd40(del(216-239))> in BMS
    *** reqs: xCd40(del(216-239)) [omission]
    *** source: 16260598-Fig-8b
  *** xTraf6[tAb] copptby[WB] Traf2[Ab] is detectable
    *** cells: HEK293<xCd40(Q234A/E235A)"mT6"> in BMS
    *** reqs: xCd40(Q234A/E235A)"mT6" [omission]
    *** source: 16260598-Fig-8a
  *** xTraf6[tAb] copptby[WB] xBmpR1b(mnr)"CA"[tAb] is detectable
    *** cells: HEK293T<xTraf6><xBmpR1b(mnr)"CA"> in BMS
    *** inhibited by: xBmpR1b(mnr/E383A)"CA/Traf6-binding-mut" [substitution]
    *** source: 18758450-Fig-3e
  *** xTraf6[tAb] copptby[WB] xTak1[tAb] is detectable
    *** cells: HEK293T<xTraf6><xTak1> in BMS
    *** source: 18758450-Fig-S5b
  *** xTraf6[tAb] copptby[WB] xTak1[tAb] is increased itpo xTab2
    *** cells: HEK293 in BMS
    *** source: 10882101(D)
  *** xTraf6[tAb] copptby[WB] xTnfaip3[tAb] is detectable
    *** cells: HEK293T<xTnfaip3><xTraf6> in BMS
    *** source: 21220427-Fig-8d
  *** xTraf6[tAb]IP ubiq[tUbAb] is increased by (rUbiq + rUbe1 + rUbc13 + rUbe2v2)
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** source: 15258597-Fig-1a
*** Traf7--
  *** Traf7[MS] copptby[WB] xMekk3[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 18206350-Fig-1b
*** TrailR1--
  *** TrailR1[Ab] prot-exp[WB] is unchanged itao St6gal1 [RNAi]
    *** cells: HD3<xHras(G12V)> in BMS
    *** source: 21550977-Fig-1b
  *** xTrailR1[tAb] copptby[WB] xNod1[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 10329646(D)
  *** TrailR2-gene mRNA[RTPCR] is detectable
    *** cells: mEFs in BMS "treated with Adriamycin for 6 hr"
    *** unaffected by: kTp53(S18A) [knockin] 
    *** unaffected by: kTp53(S18A/S23A) [knockin] 
    *** source: 16757976-Fig-2a
  *** TrailR2-gene mRNA[RTPCR] is detectable
    *** cells: mEFs in BMS "treated with Adriamycin for 12 hr"
    *** unaffected by: kTp53(S18A) [knockin] 
    *** unaffected by: kTp53(S18A/S23A) [knockin] 
    *** source: 16757976-Fig-2a
  *** TrailR2-gene mRNA[RTPCR] is detectable
    *** cells: mThyCs in BMS "treated with IR for 18 hr"
    *** inhibited by: kTp53(S18A) [knockin] 
    *** inhibited by: kTp53(S18A/S23A) [knockin] 
    *** reqs: Tp53 [KO]
    *** source: 16757976-Fig-4b
  *** TrailR2[Ab] prot-exp[WB] is unchanged itao St6gal1 [RNAi]
    *** cells: HD3<xHras(G12V)> in BMS
    *** source: 21550977-Fig-1b
*** TRE--
  *** TRE-reporter[CAT] is increased itpo (xMap4k4 + xJnk1)
    *** cells: HEK293T<xMap4k4><xJnk1> in BMS
    *** reqs: xMap4k4 [omission]
    *** reqs: xJnk1 [omission]
    *** inhibited by: xMap4k4(K54R) [substitution]
    *** source: 9890973-Fig-4d
  *** TRE-reporter[Luc] is increased itpo (xJun + xFos)
    *** cells: F9 in BMS
    *** partially inhibited by: rSmad3(1-210)"LN-term" [addition]
    *** unaffected by: rSmad1(mnr)"LN-term" [substitution]
    *** source: 9732876-Fig-4a
  *** TRE-reporter[Luc] is increased itpo (xSmad3 + xSmad4)
    *** cells: MV1LU in BMS
    *** inhibited by: xJun(235-331)"DN" [addition]
    *** source: 9732876-Fig-4a
  *** TRE-reporter[Luc] is increased itpo xFos
    *** cells: F9 in BMS
    *** enhanced by: xSmad3 [addition]
    *** unaffected by: xSmad4 [addition]
    *** source: 9732876-Fig-1b
  *** TRE-reporter[Luc] is increased itpo xJun
    *** cells: F9 in BMS
    *** enhanced by: xSmad3 [addition]
    *** enhanced by: xFos [addition]
    *** unaffected by: xSmad4 [addition]
    *** source: 9732876-Fig-1b
  *** TRE-reporter[Luc] is increased itpo xJun
    *** cells: SW4807<Smad4~null> in BMS
    *** enhanced by: xSmad3 [addition]
    *** enhanced by: xFos [addition]
    *** unaffected by: xSmad4 [addition]
    *** source: 9732876-Fig-1c
  *** TRE-reporter[Luc] is increased itpo xSmad3
    *** cells: F9 in BMS
    *** enhanced by: xSmad4 [addition]
    *** source: 9732876-Fig-1b
  *** rTrf1[Ab] boundby[WB] rAtm(2842-3056)[GST] is detectable
    *** cells: none
    *** inhibited by: rAtm(1-246) [substitution]
    *** inhibited by: rAtm(250-522) [substitution]
    *** inhibited by: rAtm(523-769) [substitution]
    *** inhibited by: rAtm(772-1102) [substitution]
    *** inhibited by: rAtm(1098-1371) [substitution]
    *** inhibited by: rAtm(1245-1435) [substitution]
    *** inhibited by: rAtm(1439-1770) [substitution]
    *** inhibited by: rAtm(1764-2138) [substitution]
    *** inhibited by: rAtm(2141-2428) [substitution]
    *** inhibited by: rAtm(2427-2841) [substitution]
    *** inhibited by: rAtm(2682-3056) [substitution]
    *** source: 15314656-Fig-4b
  *** rTrf2[Ab] boundby[WB] rAtm(1439-1770)[GST] is detectable
    *** cells: none
    *** inhibited by: rAtm(1-246) [substitution]
    *** inhibited by: rAtm(250-522) [substitution]
    *** inhibited by: rAtm(523-769) [substitution]
    *** inhibited by: rAtm(772-1102) [substitution]
    *** inhibited by: rAtm(1098-1371) [substitution]
    *** inhibited by: rAtm(1245-1435) [substitution]
    *** unaffected by: rAtm(1764-2138) [substitution]
    *** inhibited by: rAtm(2141-2428) [substitution]
    *** inhibited by: rAtm(2427-2841) [substitution]
    *** inhibited by: rAtm(2842-3056) [substitution]
    *** inhibited by: rAtm(2682-3012) [substitution]
    *** source: 15314656-Fig-4b
  *** xTrf2[Ab] copptby[WB] Atm[Ab] is detectable
    *** cells: IMR90<xTrf2> in BMS
    *** source: 15314656-Fig-4a
  *** xTrf2[Ab] copptby[WB] CyclinD1[Ab] is undetectable
    *** cells: IMR90<xTrf2> in BMS
    *** source: 15314656-Fig-4a
  *** xTrh[3H] internalization[Surface-strip] is detectable
    *** cells: COS<xTrhR><xArrb2> in BMS
    *** partially reqs: xArrb2 [omission]
    *** unaffected by: xArrb2(L395A) [substitution]
    *** source: 12167659-Fig-6b
*** Trif--
  *** xTrif(mnr)"delC"[tAb] copptby[WB] xIkke[tAb] is detectable
    *** cells: HEK293<xTrif(mnr)"delC"><xIkke> in BMS
    *** unaffected by: xIkke(mnr)"KD" [substitution]
    *** source: 14530355-Fig-4b
  *** xTrif(mnr)"delC"[tAb] copptby[WB] xTbk1[tAb] is detectable
    *** cells: HEK293<xTrif(mnr)"delC"><xTbk1> in BMS
    *** inhibited by: xTbk1(mnr)"KD" [substitution]
    *** source: 14530355-Fig-4b
  *** xTrif(mnr)"delC"[tAb] copptby[WB] xTraf6[tAb] is detectable
    *** cells: HEK293<xTrif(mnr)"delC"><xTraf6> in BMS
    *** source: 14530355-Fig-2d
  *** xTrif[Ab] copptby[WB] xTradd[tAb] is detectable
    *** cells: HEK293T in BMS
    *** enhanced by: xTrif [addition]
    *** source: 18641654-Fig-6a
  *** xTrif[tAb] copptby[WB] Irf3[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 12471095-Fig-4c
  *** xTrif[tAb] copptby[WB] Ripk1[Ab] is detectable
    *** cells: HEK293<xTrif> in BMS
    *** unaffected by: xPeli1 [addition]
    *** source: 19734906-Fig-6c
  *** xTrif[tAb] copptby[WB] xAzi2[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 15611223-Fig-1b
  *** xTrif[tAb] copptby[WB] xIkk2[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 14739303-Fig-3a
  *** xTrif[tAb] copptby[WB] xIkke[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 14739303-Fig-3a
  *** xTrif[tAb] copptby[WB] xIrf7[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 14739303-Fig-1b
  *** xTrif[tAb] copptby[WB] xRipk1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 15064760-Fig-1b
  *** xTrif[tAb] copptby[WB] xRipk2[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 15064760-Fig-1b
  *** xTrif[tAb] copptby[WB] xRipk3[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 15064760-Fig-1b
  *** xTrif[tAb] copptby[WB] xRipk4[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 15064760-Fig-1b
  *** xTrif[tAb] copptby[WB] xTank[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 15611223-Fig-1a
  *** xTrif[tAb] copptby[WB] xTbk1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 14739303-Fig-3a
  *** xTrif[tAb] copptby[WB] xTicam2[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 14517278-Fig-6b
  *** xTrif[tAb] copptby[WB] xTLR2[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12471095-Fig-4a
  *** xTrif[tAb] copptby[WB] xTLR2[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 12539043-Fig-3b
  *** xTrif[tAb] copptby[WB] xTLR3[tAb] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xTLR3(A795H) [substitution]
    *** unaffected by: PolyIC (tnr) [stim]
    *** source: 12539043-Fig-3a,3b
  *** xTrif[tAb] copptby[WB] xTLR3[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12471095-Fig-4a
  *** xTrif[tAb] copptby[WB] xTLR4[tAb] is detectable
    *** cells: HEK293<xMd2><xTicam2> in BMS
    *** reqs: xTicam2 [omission]
    *** inhibited by: xTLR4(P714H)"Tir-Domain-mut" [substitution]
    *** source: 14519765(D)
  *** xTrif[tAb] copptby[WB] xTLR4[tAb] is undetectable
    *** cells: HEK293<xMd2> in BMS
    *** source: 12539043-Fig-3b
  *** xTrif[tAb] copptby[WB] xTraf3[Ab] is detectable
    *** cells: HEK293T in BMS
    *** source: 16306936-Fig-2a
  *** xTrif[tAb] copptby[WB] xTraf6[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 14739303-Fig-3a
  *** rTrio(1225-1537)[His] boundby[WB] rCdc42{NucFree}[GST] is undetectable
    *** cells: none
    *** source: 11595749-Fig-1a
  *** rTrio(1225-1537)[His] boundby[WB] rCdc42{NucFree}[GST] is undetectable
    *** cells: none
    *** source: 11595749-Fig-2a
  *** rTrio(1225-1537)[His] boundby[WB] rCdc42{NucFree}[GST] is undetectable
    *** cells: none
    *** source: 11595749-Fig-2c
  *** rTrio(1225-1537)[His] boundby[WB] rRac1{NucFree}[GST] is detectable
    *** cells: none
    *** partially inhibited by: rRac1(A59G) [substitution]
    *** inhibited by: rRac1(Q61L) [substitution]
    *** inhibited by: rRac1(Y64A) [substitution]
    *** partially inhibited by: rRac1(D65A) [substitution]
    *** inhibited by: rRac1(R66A/L67A) [substitution]
    *** partially inhibited by: rRac1(L70A/S71A) [substitution]
    *** partially inhibited by: rRac1(Q47D) [substitution]
    *** source: 11595749-Fig-2a
  *** rTrio(1225-1537)[His] boundby[WB] rRac1{NucFree}[GST] is detectable
    *** cells: none
    *** partially inhibited by: rRac1(E31A) [substitution]
    *** partially inhibited by: rRac1(Y32A) [substitution]
    *** partially inhibited by: rRac1(I33A) [substitution]
    *** partially inhibited by: rRac1(T35A) [substitution]
    *** inhibited by: rRac1(D38A) [substitution]
    *** inhibited by: rRac1(N39A) [substitution]
    *** source: 11595749-Fig-2a
  *** rTrio(1225-1537)[His] boundby[WB] rRac1{NucFree}[GST] is detectable
    *** cells: none
    *** source: 11595749-Fig-1a
  *** rTrip6[Ab] boundby[WB] rLpaR2(296-351)[GST] is detectable
    *** cells: none
    *** source: 14688263-Fig-2
  *** xTrip6[Ab] copptby[WB] xAmpka2[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 16624523(D)
  *** Trip6[Ab]IP Yphos[pYAb] is detectable
    *** cells: mEFs<Src~null><Yes1~null><Fyn~null><xSrc> in BMLS
    *** reqs: xSrc [omission]
    *** source: 15988003-Fig-1b
  *** rTrip6[GST] Yphos[pYAb] is increased by rSrc
    *** cells: none
    *** inhibited by: rTrip6(Y55F) [substitution]
    *** source: 15988003-Fig-2b
  *** rTrip6[GST] Yphos[pYAb] is increased by rSrc
    *** cells: none
    *** inhibited by: rTrip6(Y55F) [substitution]
    *** unaffected by: rTrip6(P58A) [substitution]
    *** source: 15988003-Fig-3a
  *** xTrip6[tAb] copptby[WB] xLpaR1[tAb] is undetectable
    *** cells: HEK293T in BMLS
    *** unaffected by: LPA (10 min) [stim]
    *** source: 14688263-Fig-3a
  *** xTrip6[tAb] copptby[WB] xLpaR2[tAb] is detectable
    *** cells: HEK293T in BMLS
    *** inhibited by: xLpaR2(del(296-351)) [substitution]
    *** source: 14688263-Fig-3a
  *** xTrip6[tAb] copptby[WB] xLpaR2[tAb] is detectable
    *** cells: HEK293T in BMLS
    *** inhibited by: xTrip6(1-278) [substitution]
    *** source: 14688263-Fig-3d
  *** xTrip6[tAb] copptby[WB] xLpaR3[tAb] is undetectable
    *** cells: HEK293T in BMLS
    *** unaffected by: LPA (10 min) [stim]
    *** source: 14688263-Fig-3a
*** Trka--
  *** xTrka[Ab] copptby[WB] xArms[tAb] is detectable
    *** cells: HEK293<xTrka><xArms> in BMS
    *** source: 15167895-Fig-2a
  *** xTrka[Ab] copptby[WB] xCrkL[tAb] is detectable
    *** cells: HEK293<xTrka><xCrkL> in BMS
    *** enhanced by: xArms [addition]
    *** source: 15167895-Fig-5d
  *** xTrka[Ab] copptby[WB] xRgs19ip1[Ab] is detectable
    *** cells: HEK293<xRgs19ip1><xTrka> in BMS
    *** unaffected by: xRgs19ip1(L142C/G143E) [substitution]
    *** source: 11251075-Fig-7b
  *** xTrka[Ab]IP Yphos[pYAb] is detectable
    *** cells: COS<xTrka> in BMS
    *** source: 15513915-Fig-2b
  *** xTrka[tAb] copptby[WB] xRasGrf1[GST] is detectable
    *** cells: COS<xTrka><xRasGrf1> in BMS
    *** source: 15513915-Fig-1b
  *** xTrkb[125I] boundby[Xlink] rBdnf[125I] is detectable
    *** cells: COS<xTrkb> in BMS
    *** source: 1710174-Fig-3
  *** xTrkb[125I] boundby[Xlink] rNtf3[125I] is detectable
    *** cells: COS<xTrkb> in BMS
    *** unaffected by: xTrkb(mnr)"del-Ykinase" [substitution]
    *** source: 1710174-Fig-3
  *** xTrkb[Ab] copptby[WB] xArms[tAb] is detectable
    *** cells: HEK293<xTrkb><xArms> in BMS
    *** source: 15167895-Fig-2a
  *** xTrkb[tAb] copptby[WB] xRasGrf1[GST] is detectable
    *** cells: COS<xTrkb><xRasGrf1> in BMS
    *** source: 15513915-Fig-1b
  *** xTrkb[tAb] snaggedby[WB] rEif3a[GST] is detectable
    *** cells: SF9<xTrkb> in BMS "treated with BDNF for 10 min"
    *** source: 10691301-Fig-3
  *** xTrkb[tAb] snaggedby[WB] rIna[GST] is undetectable
    *** cells: SF9<xTrkb> in BMS "treated with BDNF for 10 min"
    *** source: 10691301-Fig-3
  *** xTrkb[tAb] snaggedby[WB] rPlcg1[GST] is detectable
    *** cells: SF9<xTrkb> in BMS "treated with BDNF for 10 min"
    *** source: 10691301-Fig-3
  *** xTrkb[tAb] snaggedby[WB] rPrph[GST] is undetectable
    *** cells: SF9<xTrkb> in BMS "treated with BDNF for 10 min"
    *** source: 10691301-Fig-3
  *** xTrkb[tAb] snaggedby[WB] rPsmb6[GST] is undetectable
    *** cells: SF9<xTrkb> in BMS "treated with BDNF for 10 min"
    *** source: 10691301-Fig-3
  *** xTrkb[tAb] snaggedby[WB] rRasGrf1(29-528)[GST] is undetectable
    *** cells: SF9<xTrkb> in BMS "treated with BDNF for 10 min"
    *** source: 10691301-Fig-3
  *** xTrkc[Ab] copptby[WB] xArms[tAb] is detectable
    *** cells: HEK293<xTrkc><xArms> in BMS
    *** source: 15167895-Fig-2a
  *** xTrkc[tAb] copptby[WB] xRasGrf1[GST] is detectable
    *** cells: COS<xTrkc><xRasGrf1> in BMS
    *** source: 15513915-Fig-1b
  *** xTrkc[tAb] snaggedby[WB] rEif3a[GST] is detectable
    *** cells: SF9<xTrkc> in BMS "treated with Ntf3 for 10 min"
    *** source: 10691301-Fig-3
  *** xTrkc[tAb] snaggedby[WB] rIna[GST] is undetectable
    *** cells: SF9<xTrkc> in BMS "treated with Ntf3 for 10 min"
    *** source: 10691301-Fig-3
  *** xTrkc[tAb] snaggedby[WB] rPlcg1[GST] is detectable
    *** cells: SF9<xTrkc> in BMS "treated with Ntf3 for 10 min"
    *** source: 10691301-Fig-3
  *** xTrkc[tAb] snaggedby[WB] rPrph[GST] is undetectable
    *** cells: SF9<xTrkc> in BMS "treated with Ntf3 for 10 min"
    *** source: 10691301-Fig-3
  *** xTrkc[tAb] snaggedby[WB] rPsmb6[GST] is undetectable
    *** cells: SF9<xTrkc> in BMS "treated with Ntf3 for 10 min"
    *** source: 10691301-Fig-3
  *** xTrkc[tAb] snaggedby[WB] rRasGrf1(29-528)[GST] is undetectable
    *** cells: SF9<xTrkc> in BMS "treated with Ntf3 for 10 min"
    *** source: 10691301-Fig-3
  *** xTrpc4ap[tAb] copptby[WB] Ikk1[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 14585990-Fig-7c
  *** xTrpc4ap[tAb] copptby[WB] Ripk1[Ab] is undetectable
    *** cells: HEK293 in BMS
    *** source: 14585990-Fig-7c
  *** xTrpc4ap[tAb] copptby[WB] TnfR1[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 14585990-Fig-7c
  *** xTrpc4ap[tAb] copptby[WB] Tradd[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 14585990-Fig-7c
  *** xTrpc4ap[tAb] copptby[WB] Traf2[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 14585990-Fig-7c
  *** xTrpc4ap[tAb] copptby[WB] xNemo[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 14585990-Fig-7a
  *** xTrpc4ap[tAb] copptby[WB] xRipk1[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 14585990-Fig-7b
  *** xTrpc4ap[tAb] copptby[WB] xTnfR1[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 14585990-Fig-2a
  *** xTrpc4ap[tAb] copptby[WB] xTraf2[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 14585990-Fig-7a
  *** xTrpv1[Ab] copptby[WB] xTrka[Ab] is detectable
    *** cells: HEK293<xTrka><xTrpv1> in BMS
    *** inhibited by: xTrka(Y791F) [substitution]
    *** source: 11418861-Fig-5a
  *** xTrpv1[Ab] copptby[WB] xTrka[Ab] is detectable
    *** cells: HEK293<xTrka><xTrpv1> in BMS
    *** unaffected by: xTrka(Y791F) [substitution]
    *** unaffected by: xTrka(Y496F) [substitution]
    *** unaffected by: xTrka(Y544F) [substitution]
    *** source: 11418861-Fig-S3
*** Trrap--
  *** Trrap[Ab] copptby[WB] Kat2a[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 10611234-Fig-5a
  *** Trrap[Ab] copptby[WB] Max[Ab] is detectable
    *** cells: COLO320 in BMS
    *** source: 9708738-Fig-4e
  *** Trrap[Ab] copptby[WB] Max[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 10611234-Fig-3a
  *** Trrap[Ab] copptby[WB] Max[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 12660246-Fig-1a
  *** Trrap[Ab] copptby[WB] Myc[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 10611234-Fig-3a
  *** Trrap[Ab] copptby[WB] xE2f1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: xE2f1(Y411C) [substitution]
    *** inhibited by: xE2f1((1-373)/Y411C) [substitution]
    *** source: 9708738-Fig-6c
  *** Trrap[Ab] copptby[WB] xKat2a[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 12660246-Fig-1a
  *** Trrap[Ab] copptby[WB] xMyc[tAb] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xMyc(111-439) [substitution]
    *** source: 9708738-Fig-4c
  *** Trrap[Ab] copptby[WB] xMyc[tAb] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xMyc(111-439) [substitution]
    *** source: 12660246-Fig-1b
  *** Trrap[Ab] copptby[WB] xMyc[tAb] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xMyc(del(20-48)) [substitution]
    *** inhibited by: xMyc(del(24-31)) [substitution]
    *** unaffected by: xMyc(del(33-38)) [substitution]
    *** inhibited by: xMyc(del(38-48)) [substitution]
    *** source: 9708738-Fig-4d
  *** Trrap[Ab] copptby[WB] xMyc[tAb] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xMyc(del(129-145)) [substitution]
    *** source: 9708738-Fig-4b
  *** Trrap[Ab] copptby[WB] xMyc[tAb] is detectable
    *** cells: HEK293 in BMS
    *** inhibited by: xTrrap(1899-2401) [addition]
    *** source: 12660246-Fig-5d
  *** Trrap[Ab] snaggedby[WB] rMyc(1-262)[tAb] is detectable
    *** cells: HELA in BMS "nuclear-extract"
    *** source: 10611234-Fig-2a
*** Tsc1--
  *** Tsc1-gene mRNA[Northern] is unchanged itpo xAkt1(myr)
    *** cells: HELA in BMS
    *** source: 12167664-Fig-3e
  *** Tsc1[Ab] prot-exp[WB] is decreased itpo xAkt1(myr)
    *** cells: HELA in BMS
    *** inhibited by: MG132 [pretreatment]
    *** source: 12167664-Fig-3a
  *** Tsc1[Ab] prot-exp[WB] is decreased itpo xAkt1(myr)
    *** cells: HELA in BMS
    *** source: 12167664-Fig-3a
  *** Tsc1[Ab]IP prot-stability[35S-pulse-chase] is decreased itpo xAkt1(myr)
    *** cells: EEF4 in BMS
    *** source: 12167664-Fig-3c
  *** xTsc1[tAb] copptby[WB] xAkt1[Ab] is detectable
    *** cells: HEK293T<xTsc1><xTsc2><xAkt1> in BMS
    *** reqs: xTsc2 [omission]
    *** source: 12167664-Fig-2b
  *** xTsc1[tAb]IP phos[32P-ATP] is unchanged by xRsk1[Ab]IP
    *** cells: none
    *** IP1from: HEK293<xTsc1><xTsc2> in BMS
    *** IP2from: HEK293<xRsk1> in BMS "treated with Egf for 10 min"
    *** source: 15342917-Fig-2a
*** Tsc2-- Tsc2-gene--
  *** Tsc2-gene mRNA[Northern] is unchanged itpo xAkt1(myr)
    *** cells: HELA in BMS
    *** source: 12167664-Fig-3e
  *** xTsc2(965-1807)[tAb] snaggedby[WB] Hras{GMPPNP}[GST] is undetectable
    *** cells: HEK293T<xTsc2(965-1807)> in BMS
    *** source: 12842888-Fig-2
  *** xTsc2(965-1807)[tAb] snaggedby[WB] Rala{GMPPNP}[GST] is detectable
    *** cells: HEK293T<xTsc2(965-1807)> in BMS
    *** source: 12842888-Fig-2
  *** xTsc2(965-1807)[tAb] snaggedby[WB] Rap1a{GMPPNP}[GST] is detectable
    *** cells: HEK293T<xTsc2(965-1807)> in BMS
    *** source: 12842888-Fig-2
  *** xTsc2(965-1807)[tAb] snaggedby[WB] Rras{GMPPNP}[GST] is undetectable
    *** cells: HEK293T<xTsc2(965-1807)> in BMS
    *** source: 12842888-Fig-2
  *** rTsc2[32P] phos[32P-ATP] is increased by rAkt1{act}
    *** cells: none
    *** partially inhibited by: xTsc2(S924A) [substitution]
    *** partially inhibited by: xTsc2(T1518A) [substitution]
    *** inhibited by: xTsc2(S924A/T1518A) [substitution]
    *** unaffected by: xTsc2(T437A/T1054A) [substitution]
    *** inhibited by: xTsc2(T437A/S924A/T1054A/T1518A)"dAktP" [substitution]
    *** comment: aa numbers refer to drosophila Tsc2 Q9U9B0
    *** comment: drome S924 corresponds to human S981
    *** comment: drome T1518 corresponds to human T1462
    *** source: 12172554-Fig-3
  *** Tsc2[Ab] copptby[WB] Akt1[Ab] is detectable
    *** cells: HELA in BMS
    *** source: 12167664-Fig-2a
  *** Tsc2[Ab] copptby[WB] Erks[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 15851026-Fig-2b
  *** Tsc2[Ab] copptby[WB] Fak1[Ab] is undetectable
    *** cells: HEK293 in BMS
    *** source: 15851026-Fig-2b
  *** xTsc2[Ab] copptby[WB] xErk2[tAb] is detectable
    *** cells: HEK293<xTsc2><xErk2> in BMS
    *** source: 15851026-Fig-2a
  *** Tsc2[Ab] copptby[WB] Ywhag[Ab] is detectable
    *** cells: TRKE2 in BMLS "stimulated with serum for 60 min"
    *** source: 12438239-Fig-5b
  *** Tsc2[Ab] phos[WBMS-PPase] is increased itpo xMek1(S281D/S222D)
    *** cells: HEK293 in BMS
    *** source: 15851026-Fig-1c
  *** Tsc2[Ab] prot-exp[WB] is decreased itpo xAkt1(myr)
    *** cells: HELA in BMS
    *** inhibited by: MG132 [pretreatment]
    *** source: 12167664-Fig-3a
  *** Tsc2[Ab] prot-exp[WB] is decreased itpo xAkt1(myr)
    *** cells: HELA in BMS
    *** source: 12167664-Fig-3a
  *** Tsc2[Ab] snaggedby[WB] rYwhag[GST] is detectable
    *** cells: MCF7 in BMLS "stimulated with serum for 60 min"
    *** source: 12438239-Fig-5b
  *** Tsc2[Ab] snaggedby[WB] rYwhag[GST] is detectable
    *** cells: NIH3T3 in BMLS "stimulated with serum for 60 min"
    *** source: 12438239-Fig-5a
  *** Tsc2[Ab] snaggedby[WB] rYwhag[GST] is detectable
    *** cells: TRKE2 in BMLS "stimulated with serum for 60 min"
    *** source: 12438239-Fig-5b
  *** Tsc2[Ab] snaggedby[WB] rYwhah[GST] is detectable
    *** cells: NIH3T3 in BMLS "stimulated with serum for 60 min"
    *** source: 12438239-Fig-5a
  *** Tsc2[Ab] snaggedby[WB] rYwhaq[GST] is detectable
    *** cells: NIH3T3 in BMLS "stimulated with serum for 60 min"
    *** source: 12438239-Fig-5a
  *** Tsc2[Ab] snaggedby[WB] rYwhaz[GST] is detectable
    *** cells: NIH3T3 in BMLS "stimulated with serum for 60 min"
    *** source: 12438239-Fig-5a
  *** Tsc2[Ab]IP phos[32Pi] is increased itpo xAkt1
    *** cells: HELA in BMS
    *** unaffected by: xAkt1(myr) [substitution]
    *** source: 12167664-Fig-1b
  *** Tsc2[Ab]IP phos[WBMS] is increased itpo xAkt1(myr)
    *** cells: HELA in BMS
    *** inhibited by: xAkt1(mnr)"DN" [substitution]
    *** source: 12167664-Fig-1f
  *** Tsc2[Ab]IP phos[WBMS] is increased itpo xPik3c?(mnr)"CA"
    *** cells: HELA in BMS
    *** source: 12167664-Fig-1f
  *** Tsc2[Ab]IP prot-stability[35S-pulse-chase] is decreased itpo xAkt1(myr)
    *** cells: EEF4 in BMS
    *** source: 12167664-Fig-3c
  *** xTsc2[Ab]IP prot-stability[35S-pulse-chase] is detectable
    *** cells: EEF8<Tsc2~null><xTsc2> in BMS
    *** inhibited by: xTsc2(S939D/S981D/S993D/S1130D/S1132D/S1462D/S1798D) [substitution]
    *** enhanced by: xTsc2(S939A/S981A/S993A/S1130A/S1132A/S1462A/S1798A) [substitution]
    *** source: 12167664-Fig-3d
  *** Tsc2[phosAb] phos(S1387)[phosAb] is detectable
    *** cells: mHepatocytes in BMS
    *** does not req: Lkb1 [KO]
    *** source: 18439900-Fig-S2
  *** Tsc2[phosAb] phos(T1462)[phosAb] is increased itpo xAkt1(myr)"CA"
    *** cells: RAT1A in BMLS
    *** unaffected by: Serum-deprivation [pretreatment]
    *** source: 16027121-Fig-2f
  *** Tsc2[phosAb] phos(T1462)[phosAb] is increased itpo xIkke
    *** cells: HELA in BMS
    *** inhibited by: xIkke(mnr)"KD" [substitution]
    *** source: 21464307-Fig-1b
  *** Tsc2[phosAb] phos(T1462)[phosAb] is increased itpo xTbk1
    *** cells: HELA in BMS
    *** inhibited by: xTbk1(mnr)"KD" [substitution]
    *** source: 21464307-Fig-1a
  *** xTsc2[tAb] phos[WBMS] is decreased itpo xPten
    *** cells: HEK293 in BMS
    *** reversed by: xPten(mnr)"CIA" [addition]
    *** source: 12172553-Fig-3a
  *** xTsc2[tAb] phos[WBMS] is increased itpo xAkt1
    *** cells: HEK293 in BMS
    *** inhibited by: LY294002 [addition]
    *** source: 12172553-Fig-3a
  *** xTsc2[tAb] phos[WBMS] is increased itpo xAkt1
    *** cells: HEK293 in BMS
    *** inhibited by: xAkt1(mnr)"KD" [substitution]
    *** source: 12172553-Fig-3a
  *** xTsc2[tAb]IP phos(RXRXXS-T)[phosAb] is increased itpo xHras(Q61L)"CA"
    *** cells: HEK293<xTsc1><xTsc2> in BMS
    *** inhibited by: xHras(S17N)"DN" [substitution]
    *** source: 15342917-Fig-1b
  *** xTsc2[tAb]IP phos(RXRXXS-T)[phosAb] is increased itpo xMek1(mnr)"CA"
    *** cells: HEK293<xTsc1><xTsc2> in BMS
    *** source: 15342917-Fig-1b
  *** xTsc2[tAb]IP STphos[pSTAb] is increased itpo xMek1(S281D/S222D)
    *** cells: HEK293<xTsc2> in BMS
    *** unaffected by: xTsc2(S540A) [substitution]
    *** partially inhibited by: xTsc2(S664A) [substitution]
    *** partially inhibited by: xTsc2(S540A/S664A) [substitution]
    *** unaffected by: xTsc2(S939A/T1462A) [substitution]
    *** source: 15851026-Fig-3d
*** Tsg101--
  *** xTsg101[tAb] copptby[WB] xHgs[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12802020(D)
  *** xTtrap[tAb] copptby[WB] xTraf2[tAb] is undetectable
    *** cells: HEK293T<xTtrap><xTraf2> in BMS
    *** source: 10764746-Fig-6a
  *** xTtrap[tAb] copptby[WB] xTraf3[tAb] is detectable
    *** cells: HEK293T<xTtrap><xTraf3> in BMS
    *** source: 10764746-Fig-6a
  *** xTtrap[tAb] copptby[WB] xTraf5[tAb] is detectable
    *** cells: HEK293T<xTtrap><xTraf5> in BMS
    *** source: 10764746-Fig-6a
  *** xTtrap[tAb] copptby[WB] xTraf6[tAb] is detectable
    *** cells: HEK293T<xTtrap><xTraf6> in BMS
    *** source: 10764746-Fig-6a
  *** xTtrap[tAb] copptby[WB] xTraf6[tAb] is detectable
    *** cells: HEK293T<xTtrap><xTraf6> in BMS
    *** unaffected by: xTraf6(289-511) [substitution]
    *** inhibited by: xTraf6(317-511) [substitution]
    *** source: 10764746-Fig-6b
  *** Tubas[Ab] copptby[WB] Pxn[Ab] is detectable
    *** cells: hPHAblasts in BMS
    *** source: 10840040-Fig-2
  *** xTubgcp3[tAb] copptby[WB] Mtor[Ab] is undetectable
    *** cells: HEK293T in BMS
    *** source: 12150925-Fig-3d
  *** xTubgcp3[tAb] copptby[WB] Mtor[Ab] is undetectable
    *** cells: HEK293T in BMS
    *** source: 15268862-Fig-1d
  *** xTubgcp3[tAb] copptby[WB] xMtor[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 12150925-Fig-3e
  *** Tubgs[Ab] copptby[WB] Pxn[Ab] is detectable
    *** cells: hPHAblasts in BMS
    *** source: 10840040-Fig-2
  *** Tyk2[Ab] copptby[WB] Stam2[Ab] is detectable
    *** cells: DAUDI in BMS
    *** source: 10899310-Fig-2d
  *** xTyk2[Ab] copptby[WB] xStam2[Ab] is detectable
    *** cells: HEK293T in BMS
    *** source: 10899310-Fig-2f
  *** xTyk2[Ab]IP Yphos[pYAb] is detectable
    *** cells: SF9 in BMS
    *** unaffected by: xStat1 [addition]
    *** source: 7657660-Fig-2b
  *** Ubc13[Ab] prot-exp[WB] is detectable-but unchanged irt IR (6 hr)
    *** cells: HELA in BMS
    *** source: 18001825-Fig-S5d
  *** Ubc13[Ab] snaggedby[WB] rBcl10[GST] is detectable
    *** cells: JURKAT<Pten~null> in BMS "cytoplasmic fraction"
    *** unaffected by: PMA + Ionomycin [addition]
    *** source: 14695475-Fig-1a
  *** Ube2d3[Ab] copptby[WB] xTnfaip3[tAb] is detectable
    *** cells: mEFs<Tnfaip3~null><xTnfaip3> in BMS "treated with IL1 for 30-60 min"
    *** inhibited by: xTnfaip3(547-775) [substitution]
    *** inhibited by: xTnfaip3(del(247-699)) [substitution]
    *** source: 20185725-Fig-4f
  *** Ube2e2-gene mRNA[RTPCR] is detectable
    *** cells: HEK293T in BMS "treated with Ifna for 8 hr"
    *** repressed by: Cbp [RNAi]
    *** source: 19171783-Fig-4c
  *** Ube2e2-gene mRNA[RTPCR] is detectable
    *** cells: U3A<Stat1~null><xStat1(K410R/K413R)> in BMS "treated with Ifna for 8 hr"
    *** enhanced by: ValproicAcid [addition]
    *** source: 19171783-Fig-3h
  *** Ube2e2-gene mRNA[RTPCR] is detectable
    *** cells: U3A<Stat1~null><xStat1> in BMS "treated with Ifna for 8 hr"
    *** inhibited by: ValproicAcid [addition]
    *** source: 19171783-Fig-3h
  *** Ube2e2[Ab] prot-exp[WB] is detectable
    *** cells: HEK293T in BMS "treated with Ifna for 24 hr"
    *** repressed by: Cbp [RNAi]
    *** source: 19171783-Fig-4d
  *** Ube2e2[Ab] prot-exp[WB] is detectable
    *** cells: U3A<Stat1~null><xStat1> in BMS "treated with Ifna for 24 hr"
    *** inhibited by: xStat1(K410Q) [substitution]
    *** inhibited by: xStat1(K413Q) [substitution]
    *** unaffected by: xStat1(K410R) [substitution]
    *** unaffected by: xStat1(K413R) [substitution]
    *** inhibited by: xStat1(K410Q/K413R) [substitution]
    *** inhibited by: xStat1(K410R/K413Q) [substitution]
    *** source: 19171783-Fig-2h
  *** Ube2e2[Ab] prot-exp[WB] is increased itao Ptpn2 [RNAi]
    *** cells: HEK293 in BMS
    *** source: 19171783-Fig-6a
  *** Ube2e2[Ab] prot-exp[WB] is increased itao Shp2 [RNAi]
    *** cells: HEK293 in BMS
    *** source: 19171783-Fig-6a
*** Ube2v2--
  *** Ube2v2[Ab] snaggedby[WB] rBcl10[GST] is detectable
    *** cells: JURKAT<Pten~null> in BMS "cytoplasmic fraction"
    *** unaffected by: PMA + Ionomycin [addition]
    *** source: 14695475-Fig-1a
*** Ubiq--
  *** Ubiq{conj}[Ab] locatedin(subnuclear-bodies)[IHC] is detectable
    *** cells: HELA in BMS "treated with IR for 6 hr"
    *** reqs: Rnf8 [RNAi]
    *** source: 18001825-Fig-5a
  *** Ubiq{conj}[Ab] locatedin(subnuclear-bodies)[IHC] is detectable
    *** cells: HELA in BMS "treated with IR for 6 hr"
    *** reqs: Ubc13 [RNAi]
    *** source: 18001825-Fig-5a
  *** Ubiq{conj}[Ab] locatedin(subnuclear-bodies)[IHC] is detectable
    *** cells: HELA<Rnf8~kd><xRnf8> in BMS "treated with IR for 6 hr"
    *** inhibited by: xRnf8(mnr)"delFHA" [substitution]
    *** inhibited by: xRnf8(mnr)"delRING" [substitution]
    *** source: 18001825-Fig-5c
  *** Ubiq{conj}[Ab] locatedin(subnuclear-bodies)[IHC] is detectable
    *** cells: mEFs in BMS "treated with IR for 6 hr"
    *** reqs: H2ax [KO]
    *** source: 18001825-Fig-S5a
  *** Ubiq{conj}[Ab] locatedin(subnuclear-bodies)[IHC] is detectable
    *** cells: mEFs in BMS "treated with IR for 6 hr"
    *** reqs: Mdc1 [KO]
    *** source: 18001825-Fig-S5c
  *** Ubiq{conj}[Ab] locatedin(subnuclear-bodies)[IHC] is detectable
    *** cells: mEFs<H2ax~null><xH2ax(K119R/K120R)> in BMS "treated with IR for 6 hr"
    *** source: 18001825-Fig-S6d
  *** Ubiq{conj}[Ab] locatedin(subnuclear-bodies)[IHC] is detectable
    *** cells: mEFs<H2ax~null><xH2ax> in BMS "treated with IR for 6 hr"
    *** reqs: xH2ax [omission]
    *** source: 18001825-Fig-S5b
  *** rUbiq{poly}[Ab] cleavage[WB] is increased by xCyld[tAb]IP
    *** cells: none
    *** IPfrom: HEK293T in BMS
    *** inhibited by: xCyld(1-932)[tAb]IP [substitution]
    *** source: 12917689-Fig-1d
  *** Ubtf[Ab] infraction(nuclear)[WB] is detectable
    *** cells: NIH3T3 in BMS "stimulated with serum"
    *** source: 15713638-Fig-6b
  *** Ubtf[Ab] infraction(nuclear)[WB] is detectable
    *** cells: HELA<xDusp6> in BMS
    *** source: 15269220-Fig-1d
  *** Ubtf[Ab] infraction(nuclear)[WB] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 15269220-Fig-1c
  *** Ubtf[Ab] infraction(nuclear)[WB] is detectable
    *** cells: NIH3T3<xDusp6> in BMS
    *** source: 15269220-Fig-1c
  *** rUsf1[14C] acetyl[14C-acetyl-CoA] is unchanged by rEp300(1195-1810)
    *** cells: none
    *** source: 9288740-Fig-1a
*** Usp6nl--
  *** rUsp6nl[35S] boundby[WB] rGrb2[GST] is detectable
    *** cells: none
    *** source: 12399475-Fig-1a
  *** rUsp6nl[35S] boundby[WB] rNck1[GST] is detectable
    *** cells: none
    *** source: 12399475-Fig-1a
  *** rUsp6nl[35S] boundby[WB] rPik3r1[GST] is detectable
    *** cells: none
    *** source: 12399475-Fig-1a
  *** Usp6nl[Ab] copptby[WB] Grb2[Ab] is detectable
    *** cells: HELA in BMS
    *** source: 12399475-Fig-3a
  *** xUsp6nl[Ab] copptby[WB] xEps8[tAb] is detectable
    *** cells: COS7 in BMS
    *** inhibited by: xAbi1 [addition]
    *** source: 11099046(D)
  *** xUsp6nl[tAb] copptby[WB] xGrb2[GST] is detectable
    *** cells: COS in BMLS
    *** unaffected by: Egf (5,15 min) [stim]
    *** source: 12399475-Fig-3b
  *** Usp21[Ab] copptby[WB] Ripk1[Ab] is detectable
    *** cells: HELA in BMS
    *** source: 19910467-Fig-2d
*** Vav1--
  *** xVav1[tAb] snaggedby[WB] rCdc42(G15N)[GST] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-1
  *** xVav1[tAb] snaggedby[WB] rRhog(G15N)"NucFree"[GST] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-1
*** Vav2--
  *** rVav2[35S] boundby[WB] rNckipsd(159-348)[GST] is detectable
    *** cells: none
    *** source: 14765113-Fig-2c
  *** rVav2[35S] boundby[WB] rNckipsd(mnr)"Cterm"[GST] is undetectable
    *** cells: none
    *** source: 14765113-Fig-2c
  *** rVav2[35S] boundby[WB] rNckipsd(mnr)"SH3"[GST] is detectable
    *** cells: none
    *** source: 14765113-Fig-2c
  *** Vav2[Ab] infraction(membrane)[WB] is detectable
    *** cells: HELA in BMS
    *** reqs: Nckipsd [RNAi]
    *** source: 14765113-Fig-6b
  *** Vav2[Ab] prot-exp[WB] is detectable
    *** cells: HELA in BMS
    *** does not req: Nckipsd [RNAi]
    *** source: 14765113-Fig-6b
  *** Vav2[Ab] prot-exp[WB] is detectable
    *** cells: HELA in BMS "membrane-fractions"
    *** reqs: Nckipsd [RNAi]
    *** source: 14765113-Fig-6a
  *** xVav2[tAb] snaggedby[WB] rCdc42(G15N)"NucFree"[GST] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-1
  *** xVav2[tAb] snaggedby[WB] rRhoa(G17A)[GST] is detectable
    *** cells: NIH3T3 in BMS
    *** source: 12376551-Fig-1
*** Vav3--
  *** xVav3(144-847)[His]IP boundby[WB] rCdc42{NucFree}[GST] is undetectable
    *** cells: none
    *** IPfrom: SF9 in BMS
    *** unaffected by: rCdc42{GDP} [substitution]
    *** unaffected by: rCdc42{GTP} [substitution]
    *** source: 10523675-Fig-5a
  *** xVav3(mnr)"ZF-Domain"[His]IP boundby[WB] rCdc42{NucFree}[GST] is undetectable
    *** cells: none
    *** IPfrom: SF9 in BMS
    *** unaffected by: rCdc42{GDP} [substitution]
    *** unaffected by: rCdc42{GTP} [substitution]
    *** source: 10523675-Fig-10b
  *** Vcl[Ab] copptby[WB] Apc[Ab] is undetectable
    *** cells: HELAS3 in BMS
    *** source: 20224554-Fig-5f
  *** Vcl[Ab] copptby[WB] Dvls[Ab] is undetectable
    *** cells: HELAS3 in BMS
    *** source: 20224554-Fig-5e
  *** Vcl[Ab] copptby[WB] Pxn[Ab] is detectable
    *** cells: OLF442 in BMS
    *** source: 15023529-Fig-3b
  *** Vcl[Ab] copptby[WB] Sorbs1[Ab] is detectable
    *** cells: CV1 in BMS
    *** source: 17082770-Fig-2a
  *** Vcl[Ab] copptby[WB] Src[Ab] is detectable
    *** cells: mEFs in BMS
    *** reqs: Rac1 [KO]
    *** source: 16698790-Fig-1a
  *** Vcl[Ab] snaggedby[WB] rPak1[GST] is undetectable
    *** cells: 3Y1 in BMS
    *** source: 11096073-Fig-1a
  *** Vcl[Ab] snaggedby[WB] rPak3[GST] is undetectable
    *** cells: 3Y1 in BMS
    *** source: 11096073-Fig-1a
  *** Vcl[Ab] snaggedby[WB] rPxn[GST] is undetectable
    *** cells: HELA in BMS
    *** comment: snag is detectable when rPxn splice variants 2,3 are used
    *** source: 9054445-Fig-3a
  *** Vcl[Ab] snaggedby[WB] rPxn[GST] is undetectable
    *** cells: U937 in BMS
    *** comment: snag is detectable when rPxn splice variants 2,3 are used
    *** source: 9054445-Fig-3a
  *** Vcl[Ab] snaggedby[WB] rSorbs1[GST] is detectable
    *** cells: CV1 in BMS
    *** partially inhibited by: rSorbs1(mnr)"SH3A" [substitution]
    *** unaffected by: rSorbs1(mnr)"SH3B" [substitution]
    *** inhibited by: rSorbs1(mnr)"SH3C" [substitution]
    *** source: 17082770-Fig-2c
  *** xVcl[tAb] copptby[WB] xSorbs1[tAb] is detectable
    *** cells: COS1<xPxn><xSorbs1> in BMS
    *** inhibited by: xSorbs1(W536F) [substitution]
    *** inhibited by: xSorbs1(W601F) [substitution]
    *** unaffected by: xSorbs1(W716F) [substitution]
    *** unaffected by: xSorbs1(W536F/W601F) [substitution]
    *** source: 17082770-Fig-2d
  *** Vegf[Ab] prot-exp[WB] is detectable
    *** cells: PANC1 in BMS
    *** does not req: EgfR [RNAi]
    *** source: 21573184-Fig-6b
  *** Vegf[Ab] prot-exp[WB] is detectable
    *** cells: PANC1 in BMS
    *** partially reqs: Src [RNAi]
    *** source: 21573184-Fig-6b
  *** Vegf[Ab] prot-exp[WB] is increased itpo xTsc2
    *** cells: LEF<Tsc2~null> in BMS
    *** unaffected by: xTsc2(S1371A/S1375A/S1337A/S1383A) [substitution]
    *** comment: aa numbers converted to Uniprot human canonical sequence
    *** source: 16959574-Fig-7g
  *** Vegf[Ab] secretion[ELISA] is decreased itpo xTsc1
    *** cells: MDAMB453 in BMS
    *** unaffected by: xTsc1(S487A/S511A) [substitution]
    *** reversed by: xTsc1(S487D/S511D) [substitution]
    *** source: 17693255-Fig-5d
  *** Vim[Ab] prot-exp[WB] is increased itpo xBraf(V600E)
    *** cells: MCF10A in BMLS
    *** inhibited by: xBraf [substitution]
    *** inhibited by: xBraf(R188L) [substitution]
    *** unaffected by: xBraf(V600E/R118L) [substitution]
    *** inhibited by: xBraf(S446A/S5447A) [substitution]
    *** unaffected by: xBraf(V600E/S446A/S5447A) [substitution]
    *** inhibited by: xBraf(S365A/S446A/S447A/D448A/D449A) [substitution]
    *** unaffected by: xBraf(V600E/S365A/S446A/S447A/D448A/D449A) [substitution]
    *** inhibited by: xBraf(S365A) [substitution]
    *** source: 16702958-Fig-8a
  *** Vim[Ab] prot-exp[WB] is increased itpo xBraf(V600E)
    *** cells: MCF10A in BMLS
    *** inhibited by: xBraf [substitution]
    *** inhibited by: xBraf(S729A) [substitution]
    *** unaffected by: xBraf(V600E/S729A) [substitution]
    *** source: 16702958-Fig-8b
  *** Vps34[Ab] copptby[WB] Becn1[Ab] is detectable
    *** cells: HT29 in BMS
    *** inhibited by: xBcl2 [addition]
    *** source: 16179260(D)
  *** Vps34[Ab] copptby[WB] Becn1[Ab] is detectable
    *** cells: U251 in BMS
    *** source: 16390869(D)
  *** Vps34[Ab] copptby[WB] xBecn1[tAb] is detectable
    *** cells: MCF7<Becn1~null> in BMS
    *** inhibited by: xBecn1(del(244-337)) [substitution]
    *** source: 16874027(D)
  *** xVps39[tAb] copptby[WB] xAcvR2b[tAb] is detectable
    *** cells: COS1 in BMLS
    *** enhanced by: xAcvR1b(mnr)"KD" [addition]
    *** unaffected by: xAcvR1b(mnr)"CA" [addition]
    *** source: 12941698-Fig-4a
  *** xVps39[tAb] copptby[WB] xAcvR2b[tAb] is detectable
    *** cells: COS1 in BMLS
    *** unaffected by: xAcvR1b(mnr)"KD" [addition]
    *** unaffected by: xAcvR1b(mnr)"CA" [addition]
    *** source: 12941698-Fig-3b,4a
  *** xVps39[tAb] copptby[WB] xBmpR2[tAb] is undetectable
    *** cells: COS1 in BMLS
    *** source: 12941698-Fig-3b
  *** xVps39[tAb] copptby[WB] xTgfbR1[tAb] is detectable
    *** cells: COS1 in BMLS
    *** enhanced by: xTgfbR1(mnr)"KD" [addition]
    *** inhibited by: xTgfbR1(mnr)"CA" [addition]
    *** source: 12941698-Fig-3a
  *** xVps39[tAb] copptby[WB] xTgfbR2[tAb] is detectable
    *** cells: COS1 in BMLS
    *** unaffected by: xTgfbR2(mnr)"KD" [substitution]
    *** unaffected by: xTgfbR1(mnr)"KD" [addition]
    *** unaffected by: xTgfbR1(mnr)"CA" [addition]
    *** source: 12941698-Fig-3a
  *** xWasp[tAb] copptby[WB] xCdc42(Q61L)[tAb] is detectable
    *** cells: COS7<xSrc> in BMS
    *** unaffected by: xSrc(Y530F) [addition]
    *** source: 14506284-Fig-3l
  *** xWdr83[tAb] copptby[WB] xErk1[tAb] is detectable
    *** cells: CCL39<xWdr83><xErk1> in BMS
    *** source: 15118098-Fig-2d
  *** xWdr83[tAb] copptby[WB] xErk2[tAb] is detectable
    *** cells: CCL39<xWdr83><xErk2> in BMS
    *** source: 15118098-Fig-2d
  *** xWdr83[tAb] copptby[WB] xLamtor3[tAb] is detectable
    *** cells: CCL39<xWdr83><xLamtor3> in BMS
    *** source: 15118098-Fig-2a
  *** xWdr83[tAb] copptby[WB] xMek1[tAb] is detectable
    *** cells: CCL39<xWdr83><xMek1> in BMS
    *** enhanced by: xLamtor3 [addition]
    *** source: 15118098-Fig-3c
  *** xWdr83[tAb] copptby[WB] xMek1[tAb] is detectable
    *** cells: CCL39<xWdr83><xMek1> in BMS
    *** enhanced by: xRaf1 [addition]
    *** enhanced by: xErk1 [addition]
    *** unaffected by: xLamtor3 [addition]
    *** source: 15118098-Fig-3a
  *** xWdr83[tAb] copptby[WB] xMek1[tAb] is detectable
    *** cells: CCL39<xWdr83><xMek1> in BMS
    *** unaffected by: xMek1(del(270-307))"dPRS" [substitution]
    *** source: 15118098-Fig-2b
  *** xWdr83[tAb] copptby[WB] xMek2[tAb] is detectable
    *** cells: CCL39<xWdr83><xMek2> in BMS
    *** source: 15118098-Fig-2b
  *** xWdr83[tAb] copptby[WB] xRaf1[tAb] is detectable
    *** cells: CCL39<xWdr83><xRaf1> in BMS
    *** source: 15118098-Fig-2d
  *** xWdr83[tAb] copptby[WB] xRaf1[tAb] is detectable
    *** cells: CCL39<xWdr83><xRaf1> in BMS
    *** unaffected by: xMek1 [addition]
    *** unaffected by: xErk1 [addition]
    *** unaffected by: xLamtor3 [addition]
    *** source: 15118098-Fig-3b
  *** xWnk1[tAb] copptby[WB] Mek1[Ab] is undetectable
    *** cells: HEK293<xWnk1> in BMS
    *** source: 10969079-Fig-7a
  *** xWnk1[tAb] copptby[WB] xOxsr1[tAb] is detectable
    *** cells: HEK293<xWnk1><xOxsr1> in BMS
    *** source: 16263722(D)
  *** xWnk1[tAb] copptby[WB] xStk39[tAb] is detectable
    *** cells: HEK293<xWnk1><xStk39> in BMS
    *** source: 16263722(D)
*** Wnk4--
  *** xWnk4[tAb] copptby[WB] xOxsr1[tAb] is detectable
    *** cells: HEK293<xWnk4><xOxsr1> in BMS
    *** source: 16263722(D)
  *** xWnk4[tAb] copptby[WB] xStk39[tAb] is detectable
    *** cells: HEK293<xWnk4><xStk39> in BMS
    *** source: 16263722(D)
  *** rWnt5a[tAb] copptby[WB] xRor2[tAb] is detectable
    *** cells: Lcells<xRor2><xFzd7> in BMS
    *** source: 20457807-Fig-3c
*** Xiap--
  *** xXiap[tAb] copptby[WB] xAcvR1(mnr)"CA"[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 11356828-Fig-1a
  *** xXiap[tAb] copptby[WB] xAcvR1b(mnr)"CA"[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 11356828-Fig-1a
  *** xXiap[tAb] copptby[WB] xAcvRl1(mnr)"CA"[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 11356828-Fig-1a
  *** xXiap[tAb] copptby[WB] xBmpR1a(mnr)"CA"[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 11356828-Fig-1a
  *** xXiap[tAb] copptby[WB] xBmpR1b(mnr)"CA"[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 11356828-Fig-1a
  *** xXiap[tAb] copptby[WB] xTgfbR1(T204D)"CA"[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 11356828-Fig-1a
  *** xXiap[tAb] copptby[WB] xTgfbR1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 11356828-Fig-3a
  *** xXiap[tAb] copptby[WB] xTgfbR1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: xTgfbR1(T204D)"CA" [substitution]
    *** unaffected by: xTgfbR1(K232R)"KD" [substitution]
    *** source: 11356828-Fig-1b
*** Yes1--
  *** Yes1[Ab] copptby[WB] Ctnnd1[Ab] is detectable
    *** cells: IEC18 in BMS
    *** enhanced by: xKras(G12V)"CA" [addition]
    *** source: 12640114-Fig-6a
  *** Yes1[Ab]IP IVKA(Ctnnd1)[pYAb] is increased itpo xKras(G12V)"CA"
    *** cells: IEC18 in BMS
    *** source: 12640114-Fig-8c
  *** Yes1[Ab]IP IVKA(Enolase)[pYAb] is increased itpo xKras(G12V)"CA"
    *** cells: IEC18 in BMS
    *** source: 12640114-Fig-8b
  *** Yes1[Ab]IP Yphos[pYAb] is increased itpo xKras(G12V)"CA"
    *** cells: IEC18 in BMS
    *** source: 12640114-Fig-8a
*** Ywha?--
  *** xYwha?[tAb] copptby[WB] xPdpk1[GST] is detectable
    *** cells: HEK293T in BMS
    *** partially inhibited by: xSmad2 [addition]
    *** partially inhibited by: xSmad3 [addition]
    *** partially inhibited by: xSmad4 [addition]
    *** partially inhibited by: xSmad7 [addition]
    *** source: 17327236-Fig-5a
*** Ywhab--
  *** xYwhab[Ab] copptby[WB] xRaf1[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 10620507-Fig-1
  *** Ywhab[MS] copptby[WB] xKsr1[tAb] is detectable
    *** cells: COS in BMS
    *** source: 12932319-Fig-1a
  *** xYwhab[tAb] copptby[WB] xPdpk1[tAb] is undetectable
    *** cells: HEK293T<xYwhab><xPdpk1> in BMS
    *** source: 12177059-Fig-1b
*** Ywhae--
  *** xYwhae(K49E)[Ab] locatedin(nucleus)[IHC] is detectable
    *** cells: U2OS<xYwhae(K49E)> in BMS
    *** source: 11864996-Fig-4d
  *** xYwhae[Ab] locatedin(cytoplasm)[IHC] is detectable
    *** cells: U2OS<xYwhae> in BMS
    *** source: 11864996-Fig-4d
  *** Ywhae[MS] copptby[WB] xKsr1[tAb] is detectable
    *** cells: COS in BMS
    *** source: 12932319-Fig-1a
  *** xYwhae[tAb] copptby[WB] xPdpk1[tAb] is undetectable
    *** cells: HEK293T<xYwhae><xPdpk1> in BMS
    *** source: 12177059-Fig-1b
  *** xYwhae[tAb] snaggedby[WB] rCamkk1{phos}[GST] is undetectable
    *** cells: COS7 in BMS
    *** comment: rCamkk1 was phosed with PKA
    *** source: 15469938(D)
*** Ywhag--
  *** xYwhag[Ab] copptby[WB] xPkcz[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 10620507-Fig-1
  *** xYwhag[Ab] copptby[WB] xRaf1[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 10620507-Fig-1
  *** Ywhag[MS] copptby[WB] xKsr1[tAb] is detectable
    *** cells: COS in BMS
    *** source: 12932319-Fig-1a
  *** xYwhag[tAb] snaggedby[WB] rCamkk1{phos}[GST] is detectable
    *** cells: COS7 in BMS
    *** comment: rCamkk1 was phosed with PKA
    *** source: 15469938(D)
*** Ywhah--
  *** xYwhah[Ab] copptby[WB] xPkcz[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 10620507-Fig-1
  *** xYwhah[Ab] copptby[WB] xRaf1[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 10620507-Fig-1
  *** xYwhah[tAb] copptby[WB] xPdpk1[tAb] is detectable
    *** cells: HEK293T<xYwhah><xPdpk1> in BMS
    *** source: 12177059-Fig-1b
  *** xYwhah[tAb] snaggedby[WB] rCamkk1{phos}[GST] is detectable
    *** cells: COS7 in BMS
    *** comment: rCamkk1 was phosed with PKA
    *** source: 15469938-Fig-3
*** Ywhaq--
  *** xYwhaq[Ab] copptby[WB] xRaf1[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 10620507-Fig-1
*** Ywhas--
  *** Ywhas[Ab] copptby[WB] Ksr1[Ab] is detectable
    *** cells: NIH3T3 in BMLS
    *** source: 9115393-Fig-3a
  *** Ywhas[Ab] copptby[WB] Ksr1[Ab] is detectable
    *** cells: PC12 in BMS "differentiated with Ngf for 5 days"
    *** source: 10409742-Fig-2g
  *** Ywhas[Ab] copptby[WB] Raf1[Ab] is increased itao Phb [RNAi]
    *** cells: HELA in BMLS
    *** source: 16041367-Fig-5b
  *** Ywhas[Ab] copptby[WB] xBraf[tAb] is detectable
    *** cells: COS1 in BMS
    *** unaffected by: xBraf(T598A) [substitution]
    *** unaffected by: xBraf(S601A) [substitution]
    *** unaffected by: xBraf(T598A/S601A) [substitution]
    *** source: 11032810-Fig-3
  *** Ywhas[Ab] copptby[WB] xBraf[tAb] is detectable
    *** cells: HEK293<xBraf> in BMS
    *** unaffected by: xRaf1 [addition]
    *** unaffected by: xBrap [addition]
    *** source: 18332145-Fig-2a
  *** Ywhas[Ab] copptby[WB] xGab2[tAb] is detectable
    *** cells: MCF10A<xGab2> in BMLS
    *** times: 0 3++ 20+ min
    *** inhibited by: xGab2(S210A/S391A) [substitution]
    *** enhanced by: xGab2(mnr)"2XR18" [substitution]
    *** inhibited by: xGab2(mnr)"2XKK" [substitution]
    *** source: 19172738-Fig-6d
  *** Ywhas[Ab] copptby[WB] xKsr1[tAb] is detectable
    *** cells: COS in BMLS
    *** unaffected by: Egf (5 min) [stim]
    *** unaffected by: xKsr1(S392A) [substitution]
    *** inhibited by: xKsr1(S392A/S297A) [substitution]
    *** source: 11741534-Fig-5b
  *** Ywhas[Ab] copptby[WB] xKsr1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** partially inhibited by: xKsr1(S309A) [substitution]
    *** partially inhibited by: xKsr1(S404A) [substitution]
    *** inhibited by: xKsr1(S309A/S404A) [substitution]
    *** source: 9858547-Fig-2b
  *** Ywhas[Ab] copptby[WB] xKsr1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xKsr1(C857Y) [substitution]
    *** source: 10409742-Fig-2b,2c
  *** Ywhas[Ab] copptby[WB] xMras(H81L)"CA"[tAb] is decreased itpo xShoc2
    *** cells: HEK293T in BMS
    *** unaffected by: xNras(G12V)"CA" [addition]
    *** source: 16630891-Fig-6b
  *** Ywhas[Ab] copptby[WB] xMras(H81L)"CA"[tAb] is detectable
    *** cells: HEK293T<xRaf1> in BMS
    *** inhibited by: xShoc2 [addition]
    *** source: 16630891-Fig-3b
  *** Ywhas[Ab] copptby[WB] xNras(G12V)"CA"[tAb] is decreased itpo (xShoc2 + xMras(H81L)"CA")
    *** cells: HEK293T in BMS
    *** partially reqs: xShoc2 [omission]
    *** partially reqs: xMras(H81L)"CA" [omission]
    *** source: 16630891-Fig-6b
  *** Ywhas[Ab] copptby[WB] xNras(G12V)"CA"[tAb] is detectable
    *** cells: HEK293T<xRaf1> in BMS
    *** unaffected by: xShoc2 [addition]
    *** source: 16630891-Fig-3b
  *** Ywhas[Ab] copptby[WB] xPfkfb2[tAb] is increased itpo xAkt1(myr)"CA"
    *** cells: HELA in BMS
    *** source: 12853467(D)
  *** Ywhas[Ab] copptby[WB] xRaf1[tAb] is detectable
    *** cells: COS1 in BMS
    *** unaffected by: xHras(G12V)"CA" [addition]
    *** inhibited by: xRaf1(S259A) [substitution]
    *** source: 11782426-Fig-5
  *** Ywhas[Ab] copptby[WB] xRaf1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: xRaf1(T491A/S494A) [substitution]
    *** unaffected by: xRaf1(T491E/S494D) [substitution]
    *** unaffected by: xRaf1(T491E/S494D/S338D/S341D) [substitution]
    *** source: 11447113-Fig-4
  *** Ywhas[Ab] copptby[WB] xRin1(294-783)"Cterm"[tAb] is detectable
    *** cells: NIH3T3<xRin1(294-783)"Cterm"> in BMS
    *** source: 9144171-Fig-2c
  *** Ywhas[Ab] copptby[WB] xRin1[Ab] is detectable
    *** cells: HEK293T in BMLS
    *** inhibited by: xRin1(S351A) [substitution]
    *** source: 11784866-Fig-6b
  *** Ywhas[Ab] infraction(cytoplasmic)[WB] is detectable
    *** cells: U2OS in BMS
    *** source: 11864996-Fig-1b
*** Ywhaz--
  *** rYwhaz[32P] phos[32P-ATP] is unchanged by rPkcz
    *** cells: none
    *** source: 10620507-Fig-6
  *** Ywhaz[Ab] copptby[WB] xCtnnb1[tAb] is detectable
    *** cells: HEK293T<xCtnnb1> in BMS
    *** source: 15492215-Fig-1a
  *** xYwhaz[Ab] copptby[WB] xPkcz[tAb] is undetectable
    *** cells: COS7 in BMS
    *** source: 10620507-Fig-1
  *** xYwhaz[Ab] copptby[WB] xRaf1[tAb] is detectable
    *** cells: COS7 in BMS
    *** source: 10620507-Fig-1
  *** rYwhaz[GST] boundby[SPR] xAraf[Ab]IP is detectable
    *** cells: none
    *** IPfrom: SF9<xAraf> in BMS
    *** source: 14688280-Fig-7a
  *** Ywhaz[MS] copptby[WB] xKsr1[tAb] is detectable
    *** cells: COS in BMS
    *** source: 12932319-Fig-1a
  *** xYwhaz[tAb] copptby[WB] xCtnnb1[tAb] is detectable
    *** cells: HEK293T<xYwhaz><xCtnnb1> in BMS
    *** source: 15492215-Fig-1c
  *** xYwhaz[tAb] copptby[WB] xPdpk1[tAb] is undetectable
    *** cells: HEK293T<xYwhaz><xPdpk1> in BMS
    *** source: 12177059-Fig-1b
*** Zbtb17--
  *** xZbtb17[Ab] boundto(Cdkn1a-gene)[ChIP] is detectable
    *** cells: HEK293T<xZbtb17> in BMS
    *** source: 20190815-Fig-2c
  *** xZbtb17[Ab] snaggedby[WB] oligo[biotin] is detectable
    *** cells: HEK293T<xGfi1><xZbtb17> in BMS
    *** does not req: xGfi1 [omission]
    *** source: 20190815-Fig-2a
  *** xZbtb17[Ab] snaggedby[WB] oligo[biotin] is detectable
    *** cells: HEK293T<xGfi1><xZbtb17><xMyc> in BMS
    *** does not req: xGfi1 [omission]
    *** source: 20190815-Fig-6b
  *** xZbtb17[tAb] copptby[WB] xGfi1[tAb] is detectable
    *** cells: HEK293T<xGfi1><xZbtb17> in BMS
    *** unaffected by: xGfi1(mnr)"delN" [substitution]
    *** inhibited by: xGfi1(mnr)"delZF3" [substitution]
    *** inhibited by: xGfi1(mnr)"delZF6" [substitution]
    *** source: 20190815-Fig-3b
*** Zfand5--
  *** xZfand5[tAb] copptby[WB] xTraf2[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 14754897-Fig-2e
  *** xZfand5[tAb] copptby[WB] xTraf6[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 14754897-Fig-2e
  *** xZfand5[tAb] oligomerization[2TagPpt] is detectable
    *** cells: HEK293 in BMS
    *** source: 14754897-Fig-5b
*** xZfyve16--
  *** xZfyve16[tAb] copptby[WB] xAcvR1[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 17272273-Fig-4e
  *** xZfyve16[tAb] copptby[WB] xAcvR1b[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 17272273-Fig-4e
  *** xZfyve16[tAb] copptby[WB] xAcvRl1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 17272273-Fig-4e
  *** xZfyve16[tAb] copptby[WB] xBmpR1a[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 17272273-Fig-4e
  *** xZfyve16[tAb] copptby[WB] xBmpR1b[tAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xZfyve16(1-886) [substitution]
    *** source: 17272273-Fig-4d
  *** xZfyve16[tAb] copptby[WB] xBmpR1b[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 17272273-Fig-4e
  *** xZfyve16[tAb] copptby[WB] xSmad1[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 17272273-Fig-4a
  *** xZfyve16[tAb] copptby[WB] xSmad2[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 17272273-Fig-4a
  *** xZfyve16[tAb] copptby[WB] xSmad2[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 17272273-Fig-4c
  *** xZfyve16[tAb] copptby[WB] xSmad3[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 17272273-Fig-4a
  *** xZfyve16[tAb] copptby[WB] xSmad4[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 17272273-Fig-4a
  *** xZfyve16[tAb] copptby[WB] xSmad4[tAb] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xZfyve16(mnr)"SBD" [substitution]
    *** source: 17272273-Fig-4c
  *** xZfyve16[tAb] copptby[WB] xSmad6[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 17272273-Fig-4a
  *** xZfyve16[tAb] copptby[WB] xSmad7[tAb] is undetectable
    *** cells: HEK293T in BMS
    *** source: 17272273-Fig-4a
  *** xZfyve16[tAb] copptby[WB] xTgfbR1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** inhibited by: xZfyve16(1-886) [substitution]
    *** source: 17272273-Fig-4d
  *** xZfyve16[tAb] copptby[WB] xTgfbR1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 17272273-Fig-4e
  *** xZnf274[Ab] copptby[WB] xTraf1[tAb] is undetectable
    *** cells: HEK293<xZnf274><xTraf1> in BMS
    *** source: 14960584-Fig-3d
  *** xZnf274[Ab] copptby[WB] xTraf2[tAb] is undetectable
    *** cells: HEK293<xZnf274><xTraf2> in BMS
    *** source: 14960584-Fig-3d
  *** xZnf274[Ab] copptby[WB] xTraf3[tAb] is undetectable
    *** cells: HEK293<xZnf274><xTraf3> in BMS
    *** source: 14960584-Fig-3d
  *** xZnf274[Ab] copptby[WB] xTraf5[tAb] is undetectable
    *** cells: HEK293<xZnf274><xTraf5> in BMS
    *** source: 14960584-Fig-3d
*** Znf364--
  *** Znf364[Ab] locatedin(perinuclear-region)[IHC] is increased itpo xRab7a
    *** cells: BHK in BMS
    *** source: 12972561(D)
  *** xZnf364[tAb] locatedin(perinuclear-region)[IHC] is increased itpo xRab7a
    *** cells: BHK in BMS
    *** inhibited by: xRab7a(T22N) [substitution]
    *** inhibited by: xRab7a(N125I) [substitution]
    *** source: 12972561(D)
  *** xZnf364[tAb]IP ubiq[UbAb] is increased by (rUbe1 + rUbe2d2 + rZnf364 + rUbiq)
    *** cells: none
    *** IPfrom: HEK293 in BMS
    *** inhibited by: xZnf364(C229S)"ring-finger-mut"[tAb]IP [substitution]
    *** source: 17462600(D)
  *** IL21-gene mRNA[RTPCR] is increased itpo xRoRc
    *** cells: mSpNaiveCD4TCs in BMS "containing anti-Cd3 + anti-Cd28"
    *** source: 17581537-Fig-S1
  *** IL21-gene mRNA[RTPCR] is increased itpo xTbet
    *** cells: mSpNaiveCD4TCs in BMS "containing anti-Cd3 + anti-Cd28"
    *** source: 17581537-Fig-S1
  *** IL21-gene mRNA[RTPCR] is unchanged itpo xCxcL9
    *** cells: mSpNaiveCD4TCs in BMS "containing anti-Cd3 + anti-Cd28"
    *** source: 17581537-Fig-S1
  *** IL21-gene mRNA[RTPCR] is unchanged itpo xFoxp3
    *** cells: mSpNaiveCD4TCs in BMS "containing anti-Cd3 + anti-Cd28"
    *** source: 17581537-Fig-S1
  *** xFoxp3[tAb] copptby[WB] xRoRc[tAb] is detectable
    *** cells: HEK293T<xRoRc><xFoxp3> in BMS
    *** inhibited by: xFoxp3(188-429)"delN" [substitution]
    *** inhibited by: xFoxp3(mnr)"delExon2" [substitution]
    *** partially inhibited by: xFoxp3(mnr)"delZnF" [substitution]
    *** unaffected by: xFoxp3(mnr)"delZip" [substitution]
    *** unaffected by: xFoxp3(mnr)"delFKH" [substitution]
    *** source: 18434325-Fig-4a
  *** IL17a-gene promo-reporter[Luc] is increased itpo xRoRc
    *** cells: HEK293T in BMS
    *** source: 18434325-Fig-2a
  *** IL17a-gene promo-reporter[Luc] is increased itpo xRoRc
    *** cells: HEK293T in BMS
    *** partially inhibited by: xFoxp3 [addition]
    *** source: 18434325-Fig-3b
  *** IL17a-gene promo-reporter[Luc] is increased itpo xRoRc
    *** cells: HEK293T in BMS
    *** inhibited by: xFoxp3 [addition]
    *** partially inhibited by: xFoxp3(188-429)"delN" [addition]
    *** partially inhibited by: xFoxp3(mnr)"delExon2" [addition]
    *** inhibited by: xFoxp3(mnr)"delZnF" [addition]
    *** inhibited by: xFoxp3(mnr)"delZip" [addition]
    *** unaffected by: xFoxp3(mnr)"delFKH" [addition]
    *** source: 18434325-Fig-4b
  *** IL17a-gene promo-reporter[Luc] is unchanged itpo xFoxp3
    *** cells: HEK293T in BMS
    *** source: 18434325-Fig-3b
  *** xRoRc[tAb] boundto(IL17a-gene)[ChIP] is detectable
    *** cells: HEK293T<xRoRc> in BMS
    *** source: 18434325-Fig-2e
  *** xRoRc[tAb] boundto(IL17a-gene)[ChIP] is detectable
    *** cells: HEK293T<xRoRc> in BMS
    *** partially inhibited by: xFoxp3 [addition]
    *** source: 18434325-Fig-3d
  *** SBE-reporter[Luc] is increased itpo xTgfbR1(mnr)"CA"
    *** cells: HEK293T in BMS
    *** unaffected by: xFoxp3 [addition]
    *** source: 18434325-Fig-3c
  *** SBE-reporter[Luc] is unchanged itpo xFoxp3
    *** cells: HEK293T in BMS
    *** source: 18434325-Fig-3c
