=================
Kinase Activation
=================

Mekk3--

  *** xP38s[tAb]IP IVKA(Atf2)[32P-ATP] is increased irt Sorbitol (30 min)
    *** cells: NIH3T3 in BMLS
    *** inhibited by: xMekk3(mnr)"DN" [addition]
    *** source: 8653792-Fig-4c

Mekk4--

  *** xP38a[tAb]IP IVKA(Atf2)[32P-ATP] is increased irt Sorbitol (20 min)
    *** cells: COS7 in BMLS
    *** inhibited by: xMekk4(K1371R)"DN" [addition]
    *** source: 9305639-Fig-10a

not Rik1--

  *** P38a[Ab]IP IVKA(Atf2)[32P-ATP] is increased irt Sorbitol (15 min)
    *** cells: mEFs in BMS
    *** does not req: Ripk1 [KO]
    *** source: 14585994-Fig-1c

not Traf2--

  *** P38a[Ab]IP IVKA(Atf2)[32P-ATP] is increased irt Sorbitol (15 min)
    *** cells: mEFs in BMS
    *** does not req: Traf2 [KO]
    *** source: 14585994-Fig-2c

  *** P38a[Ab]IP IVKA(Atf2)[32P-ATP] is increased irt Sorbitol (times)
    *** cells: HELA in BMS
    *** times: 0 15+ 30++ 60++ 120++ min
    *** source: 7535770-Fig-5
  *** xP38a[tAb]IP IVKA(Atf2)[32P-ATP] is increased irt Sorbitol (15 min)
    *** cells: HELA in BMS
    *** source: 9430721-Fig-5
  *** xP38a[tAb]IP IVKA(Atf2)[32P-ATP] is increased irt Sorbitol (20 min)
    *** cells: HEK293T<xP38a> in BMS
    *** source: 10575011-Fig-1a
  *** xP38a[tAb]IP IVKA(Atf2)[32P-ATP] is increased irt Sorbitol (20 min)
    *** cells: HELA in BMS
    *** source: 8663524-Fig-5
  *** xP38a[tAb]IP Yphos[pYAb] is increased irt Sorbitol (30 min)
    *** cells: HELA in BMS
    *** source: 9003778-Fig-3a
  *** xP38b[tAb]IP IVKA(Atf2)[32P-ATP] is increased irt Sorbitol (20 min)
    *** cells: HELA in BMS
    *** source: 8663524-Fig-5
  *** xP38b[tAb]IP IVKA(Atf2)[32P-ATP] is increased irt Sorbitol (times)
    *** cells: HELA in BMS
    *** times: 0 15 45+ min
    *** source: 9430721-Fig-5
  *** xP38g[tAb]IP IVKA(Atf2)[32P-ATP] is increased irt Sorbitol (15 min)
    *** cells: HELA in BMS
    *** source: 9430721-Fig-5
  *** P38s[Ab]IP IVKA(Atf2)[32P-ATP] is increased irt Sorbitol (15 min)
    *** cells: HEK293 in BMS
    *** source: 10347227-Fig-6b
  *** P38s[Ab]IP IVKA(Atf2)[32P-ATP] is increased irt Sorbitol (times)
    *** cells: NIH3T3 in BMLS
    *** times: 0 10+ 30+ min
    *** source: 8653792-Fig-4a


===========================
Phosphorylation on TGY site
===========================

not Mlk3--

  *** P38s[phosAb] phos(TGY)[phosAb] is increased irt Sorbitol (times)
    *** cells: mEFs in BMS
    *** times: 0 5+ 15+ 30+ 45+ 60+ 90+ 120+ min
    *** does not req: Mlk3 [KO]
    *** source: 15831472-Fig-8b

not Stat1--

  *** xP38s[phosAb] phos(TGY)[phosAb] is increased irt Sorbitol (tnr)
    *** cells: COS7<xSumo1> in BMS
    *** unaffected by: xStat1(S727E) [substitution]
    *** unaffected by: xStat1(S727D) [substitution]
    *** unaffected by: xStat1(S727A) [substitution]
    *** source: 17897103-Fig-5a
  *** xP38s[phosAb] phos(TGY)[phosAb] is increased irt Sorbitol (times)
    *** cells: COS7<xSumo1> in BMS
    *** times: 0+ 30++ 60++ min
    *** unaffected by: xStat1(S727A) [substitution]
    *** source: 17897103-Fig-4b

chemicals

  *** xP38s[phosAb] phos(TGY)[phosAb] is increased irt Sorbitol (times)
    *** cells: COS7<xSumo1> in BMS
    *** times: 0 10+ 30++ 60++ min
    *** unaffected by: SB202190 [addition]
    *** unaffected by: PD98059 [addition]
    *** source: 17897103-Fig-3c
  *** xP38s[phosAb] phos(TGY)[phosAb] is increased irt Sorbitol (times)
    *** cells: COS7<xSumo1> in BMS
    *** times: 0+ 15++ 60++ min
    *** unaffected by: SB202190 [addition]
    *** source: 17897103-Fig-2c
  *** xP38s[phosAb] phos(TGY)[phosAb] is increased irt Sorbitol (times)
    *** cells: COS7<xSumo1> in BMS
    *** times: 0+ 30++ 60++ min
    *** unaffected by: SB202190 [addition]
    *** unaffected by: xStat1(S727A) [substitution]
    *** source: 17897103-Fig-4b
