=============
Oligo binding
=============

requires K320R, Pcaf

  *** rTp53[Ab] oligo-binding[EMSA] is detectable
    *** cells: none
    *** comment: enhanced by pre-acetyl with Pcaf
    *** comment: enhancement is reversed when rTp53(K319R/K320R/K321R) is substituted
    *** source: 9891054-Fig-5
  *** rTp53 oligo-binding[EMSA] is detectable
    *** cells: none
    *** comment: enhanced by pre-acetyl with rPcaf
    *** source: 9744860-Fig-5a

=========
Reporters
=========

requires K320

  *** Tp53-reporter[SAP] is increased itpo xTp53
    *** cells: SAOS2 in BMS
    *** partially inhibited by: xTp53(K319R/K320R/K321R) [substitution]
    *** partially inhibited by: xTp53(K320R) [substitution]
    *** unaffected by: xTp53(K351R) [substitution]
    *** source: 9891054-Fig-6






















