=====================
Relocation to nucleus
=====================

not Fadd--

  *** xStat1[XFP] locatedin(nucleus)[IHC] is increased irt Ifng (1 hr)
    *** cells: mEFs in BMS
    *** does not req: Fadd [KO]
    *** source: 15549108-Fig-S3b

not Pias1--

  *** Stat1[Ab] infraction(nuclear)[WB] is increased irt Ifng
    *** cells: mEFs in BMS
    *** times: 0+ 15++ 60++ 120+ min
    *** unaffected by: Pias1 [KO]
    *** source: 17606919-Fig-7b

not Pias2--

  *** Stat1[Ab] infraction(nuclear)[WB] is increased irt Ifng
    *** cells: mEFs in BMS
    *** times: 0+ 15++ 60++ 120+ min
    *** unaffected by: Pias4 [KO]
    *** source: 17606919-Fig-7a

required features including Y701 phos site

  *** xStat1[tAb] locatedin(nucleus)[IHC] is increased irt Ifng (30 min)
    *** cells: HUH7<xStat1> in BMS
    *** inhibited by: xStat1(Y701A) [substitution]
    *** inhibited by: xStat1(R378A/K379A) [substitution]
    *** inhibited by: xStat1(K410A/K413A) [substitution]
    *** inhibited by: xStat1(K413A/R418A) [substitution]
    *** source: 11150296-Fig-5
  *** xStat1[XFP] locatedin(nucleus)[IHC] is increased irt Ifng (1 hr)
    *** cells: HELAS3<xStat1> in BMS
    *** times: 0+ 1++ 8+ hr
    *** inhibited by: xStat1(L407A/L409A) [substitution]
    *** inhibited by: xStat1(L407T/L409T) [substitution]
    *** partially inhibited by: xStat1(L407V/L409V) [substitution]
    *** inhibited by: xStat1(K410E/K413E) [substitution]
    *** source: 11823427-Fig-1a
  *** Stat1[Ab] infraction(nuclear)[WB] is increased irt Ifng (15 min)
    *** cells: 2C4 in BMS
    *** comment: Stat1 in nuc-fraction is phosed on Y701 [phosAb]
    *** source: 15935617-Fig-5b
  *** xStat1[Ab] locatedin(nucleus)[IHC] is increased irt Ifng (30 min)
    *** cells: U3A<Stat1~null><xStat1> in BMS
    *** unaffected by: xStat1(N460A) [substitution]
    *** unaffected by: xStat1(K336A) [substitution]
    *** source: 11350940-Fig-6c
  *** xStat1[Ab] locatedin(nucleus)[IHC] is increased irt Ifng (times)
    *** cells: mEFs<Stat1~null> in BMS
    *** times: 0 30+ 360 min
    *** unaffected by: xStat1(E705A) [substitution]
    *** comment: substitution with xStat1(K703R) causes retention in the nucleus at 360 min
    *** source: 16857984-Fig-5
  *** xStat1[XFP] locatedin(nucleus)[IHC] is increased irt Ifng (30 min)
    *** cells: HT1080<xStat1> in BMS
    *** unaffected by: xStat1(L407A) [substitution]
    *** source: 11927559-Fig-4a
  *** xStat1[XFP] locatedin(nucleus)[IHC] is increased irt Ifng (30 min)
    *** cells: U3A<Stat1~null><xStat1> in BMS
    *** inhibited by: xStat1(R602L) [substitution]
    *** unaffected by: xStat1(R405A) [substitution]
    *** inhibited by: xStat1(L407A) [substitution]
    *** unaffected by: xStat1(K410A) [substitution]
    *** source: 11927559-Fig-1
  *** xStat1[XFP] locatedin(nucleus)[IHC] is increased irt Ifng (times)
    *** cells: HELAS3<xStat1> in BMS
    *** times: 0+ 1++ 8+ hr
    *** unaffected by: xStat1(F404Y) [substitution]
    *** source: 11823427-Fig-1a

chemicals

  *** xStat1[XFP] locatedin(nucleus)[IHC] is increased irt Ifng (times)
    *** cells: U3A<Stat1~null><xStat1> in BMS "treated with CHX; nuclear extracts"
    *** times: 0 30++ 60++ 120+ 240+ 480 min
    *** comment: return to cytoplasm is inhibited by LMB pretreatment
    *** source: 11080165-Fig-2a

no extras

  *** Stat1[Ab] locatedin(nucleus)[IHC] is increased irt Ifng (1 hr)
    *** cells: MDAMB468 in BMS
    *** source: 14565859-Fig-3a,3b
  *** Stat1[Ab] locatedin(nucleus)[IHC] is increased irt Ifng (1 hr)
    *** cells: SKBR3 in BMS
    *** source: 14565859-Fig-3c,3d
  *** Stat1[Ab] locatedin(nucleus)[IHC] is increased irt Ifng (30 min)
    *** cells: A431 in BMS
    *** source: 12270932-Fig-2a
  *** xStat1[XFP] locatedin(nucleus)[IHC] is increased irt Ifng (30 min)
    *** cells: U3A<Stat1~null><xStat1> in BMS
    *** source: 11080165-Fig-1a
  *** xStat1[Ab] infraction(nuclear)[WB] is detectable-but unchanged irt Ifng (30 min)
    *** cells: U3A<Stat1~null><xStat1> in BMS
    *** source: 11823427-Fig-1b
  *** Stat1[Ab]IP infraction(nuclear)[WB] is increased irt Ifng (times)
    *** cells: HEPG2 in BMS
    *** times: 0 2+ 4+ 8+ hr
    *** source: 10201928-Fig-4a
