===============
Kinase Activity
===============

  *** Mkk4[Ab]IP IVKA(Jnk1,Jun)[32P-ATP] is increased irt Tnf (times)
    *** cells: HELA in BMS
    *** times: 0 5+ 10+ min
    *** source: 9535930-Fig-5b
  *** Mkk4[Ab]IP IVKA(Jnk1,Jun)[32P-ATP] is unchanged irt Tnf (15 min)
    *** cells: mEFs in BMS
    *** source: 11390361-Fig-1b
  *** Mkk4[Ab]IP IVKA(Jnk1)[32P-ATP] is increased irt Tnf (10 min)
    *** cells: HEK293 in BMS
    *** comment: unaffected by rGadd45b in IVKA
    *** source: 14743220-Fig-3e
  *** xMkk4[tAb]IP IVKA(Jnk1,Jun)[32P-ATP] is unchanged irt Tnf (30 min)
    *** cells: HEK293 in BMLS
    *** source: 9891090-Fig-9
  *** Mkk4[Ab]IP IVKA(Jnk1,Jun)[32P-ATP] is increased irt Tnf (times)
    *** cells: KB in BMS
    *** times: 0 5+ 15+ 30 60 120 180 min
    *** source: 9384583-Fig-5a
  *** Mkk4[Ab]IP IVKA(Jnk1,Jun)[32P-ATP] is increased irt Tnf (times)
    *** cells: U937 in BMS
    *** times: 0 5+ 15+ 30+ 60 120 180 min
    *** source: 9384583-Fig-5a

=======================
Phosphorylation on T261
=======================

not Irak4--

  *** Mkk4[phosAb] phos(T261)[phosAb] is increased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0 15+ 30 min
    *** unaffected by: xIrak4(K213A/K214A)"KD" [addition]
    *** source: 17337443-Fig-3c

Chemicals

  *** Mkk4[phosAb] phos(T261)[phosAb] is increased irt Tnf (15 min)
    *** cells: hUVECs in BMS
    *** inhibited by: Ebselen [pretreatment]
    *** source: 14720501-Fig-5

=====================================
Phosphorylation on an unreported site
=====================================

Tpl2--

  *** Mkk4[phosAb] phos(sitenr)[phosAb] is increased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0 10+ 20+ 30+ 40+ 60+ min
    *** reqs: Tpl2 [KO]
    *** source: 15833743-Fig-4

not Ikba--

  *** Mkk4[phosAb] phos(sitenr)[phosAb] is increased irt Tnf (times)
    *** cells: 3DO in BMS
    *** times: 0 5+ 10+ 20+ 40+ 80+ 160+ min
    *** unaffected by: xIkba(S32A/S36A/S283A/S288A/T291A/S293A/T296A)"DN" [addition]
    *** source: 14743220-Fig-2d

No extras

  *** Mkk4[phosAb] phos(sitenr)[phosAb] is increased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0 10+ 20+ 45 60 180 min
    *** source: 15545623-Fig-5a

