==========================
IL4 binding requires IL2Rg
==========================

  *** xIL4R[125I] boundby[Xlink] rIL4[125I] is detectable
    *** cells: COS7<xIL4R> in BMS
    *** reqs: xIL4R [omission]
    *** enhanced by: xIL2Rg [addition]
    *** unaffected by: xIL2Rb [addition]
    *** source: 8266078-Fig-1a
  *** xIL4R[125I] boundby[Xlink] rIL4[125I] is detectable
    *** cells: COS7<xIL4R><xIL2Rg> in BMS
    *** enhanced by: xIL2Rg(mnr)"del-SH2" [substitution]
    *** enhanced by: xIL2Rg(mnr)"del-Cterm" [substitution]
    *** source: 8266078-Fig-1a

==================
Effects of IL13Ra?
==================

  *** rIL4[125I] receptor-binding[RIA] is detectable
    *** cells: CHO<xIL13Ra1><xIL4R> in BMS
    *** comment: can be displaced by IL13
    *** source: 9013879-Fig-3



=================================
Tyrosine Phosphorylation of IL4R
=================================

  *** IL4R[Ab]IP Yphos[pYAb] is increased irt IL4 (5 min)
    *** cells: HT29 in BMS
    *** comment: anti-IL4R Ab "P7" sees wrong size protein (140 kD)
    *** source: 8609418-Fig-4a
  *** IL4R[Ab]IP Yphos[pYAb] is increased irt IL4 (5 min)
    *** cells: WIDR in BMS
    *** comment: anti-IL4R Ab "P7" sees wrong size protein (140 kD)
    *** source: 8609418-Fig-4a
  *** IL4R[Ab]IP Yphos[pYAb] is increased irt IL4 (10 min)
    *** cells: hPHAblasts in BMS
    *** source: 7822337-Fig-4b
  *** IL4R[Ab]IP Yphos[pYAb] is increased irt IL4 (10 min)
    *** cells: TF1 in BMS
    *** source: 7822337-Fig-4a
  *** IL4R[Ab]IP Yphos[pYAb] is increased irt IL4 (times)
    *** cells: mSpCs in BMS "blasted with anti-TcRb/IL2"
    *** times: 0 1+ 5+ min
    *** inhibited by: kIL4R(Y500F) [knockin]
    *** source: 14557412-Fig-2a
  *** xIL4R[Ab]IP Yphos[pYAb] is increased irt IL4 (tnr)
    *** cells: COS7 in BMLS
    *** source: 8916957-Fig-7a
  *** IL4R[Ab]IP Yphos[pYAb] is increased irt IL4 (tnr)
    *** cells: FDCP1<xIrs1> in BMLS "IL3-deprived"
    *** source: 8124718-Fig-5
  *** IL4R[Ab]IP Yphos[pYAb] is increased irt IL4 (tnr)
    *** cells: mSpCs<Cd4~neg><Cd45~neg><Cd8~pos> in BMS "treated with anti-Cd3,anti-Cd28/IL2"
    *** source: 17200144-Fig-2a
