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Mek1 is phosphorylated on T292 by activated Erk2
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  *** rMek1[32P] phos[32P-ATP] is increased by rErk2{act}
    *** cells: none
    *** comment: rErk2 activated by coexpression of rMek(del(32-51)/S218D/S222D) in e.coli
    *** unaffected by: rMek1(T292A) [substitution]
    *** unaffected by: rMek1(S298A) [substitution]
    *** unaffected by: rMek1(T292A/S298A) [substitution]
    *** source: 11948406-Fig-3a
  ----------------------------------------------------------------------
  *** rMek1[phosAb] phos(T292)[phosAb] is increased by rErk2{act}
    *** cells: none
    *** comment: rErk2 activated by coexpression of rMek(del(32-51)/S218D/S222D) in e.coli
    *** source: 11948406-Fig-3b
  *** rMek1[phosAb] phos(T292)[phosAb] is increased by rErk2(mnr)"CA"
    *** cells: none
    *** source: 14993270-Fig-5a
  ----------------------------------------------------------------------
  *** xMek1[tAb]IP phos(T292)[phosAb] is increased itpo xErk2
    *** cells: COS1 in BMLS
    *** source: 14993270-Fig-4b
  *** xMek1[tAb]IP phos(T292)[phosAb] is unchanged itpo xErk2
    *** cells: COS1 in BMLS "in suspension"
    *** source: 14993270-Fig-7a,7b
  ----------------------------------------------------------------------
  *** xMek1(S218D/S222D)"CA"[tAb]IP phos(T292)[phosAb] is increased itpo xErk2
    *** cells: COS1 in BMLS
    *** unaffected by: xMek1(T386A) [substitution]
    *** unaffected by: xMek1(T386D) [substitution]
    *** source: 14993270-Fig-6b
  *** xMek1(S218D/S222D)"CA"[tAb]IP phos(T292)[phosAb] is increased itpo xErk2
    *** cells: COS1 in BMLS
    *** source: 14993270-Fig-3b,6b
  *** xMek1(S218D/S222D)"CA"[tAb]IP phos(T292)[phosAb] is increased itpo xErk2
    *** cells: COS1 in BMLS "in suspension"
    *** source: 14993270-Fig-7b,8a,8b

====================================================
Mek1 is not phosphorylated on S298 by activated Erk2
====================================================

  *** rMek1[phosAb] phos(S298)[phosAb] is unchanged by rErk2{act}
    *** cells: none
    *** comment: rErk2 activated by coexpression of rMek(del(32-51)/S218D/S222D) in e.coli
    *** source: 11948406-Fig-3b
  ----------------------------------------------------------------------
  *** xMek1[tAb]IP phos(S298)[phosAb] is unchanged itpo xErk2
    *** cells: COS1 in BMS
    *** source: 14993270-Fig-2b
  *** xMek1[tAb]IP phos(S298)[phosAb] is unchanged itpo xErk2
    *** cells: COS1 in BMLS
    *** source: 14993270-Fig-2b
  ----------------------------------------------------------------------
  *** xMek1(S218D/S222D)"CA"[tAb]IP phos(S298)[phosAb] is decreased itpo xErk2
    *** cells: COS1 in BMLS
    *** inhibited by: xMek1(T292A) [substitution]
    *** source: 14993270-Fig-4a,6b
  *** xMek1(S218D/S222D)"CA"[tAb]IP phos(S298)[phosAb] is decreased itpo xErk2
    *** cells: COS1 in BMLS
    *** inhibited by: xErk2(T183A)"KD" [substitution]
    *** source: 14993270-Fig-3b
  *** xMek1(S218D/S222D)"CA"[tAb]IP phos(S298)[phosAb] is decreased itpo xErk2
    *** cells: COS1 in BMLS
    *** source: 14993270-Fig-3b,6b
  *** xMek1(S218D/S222D)"CA"[tAb]IP phos(S298)[phosAb] is decreased itpo xErk2
    *** cells: COS1 in BMLS
    *** partially inhibited by: U0126 [addition]
    *** source: 14993270-Fig-4a

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Other Stuff
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  *** rMek1(265-301)[32P] phos[32P-ATP] is increased by rErk2
    *** cells: none
    *** source: 9677429-Fig-4
