================
Rac1 GTP binding
================

requires Pxn phosphorylation sites S83 and Y118

  *** Rac1[Ab] GTP-association[BDPD] is increased irt Hgf (10 min)
    *** cells: MIMCD3<xPxn> in BMLS
    *** inhibited by: xPxn(S83A) [substitution]
    *** inhibited by: xPxn(Y118A/F120V/P121A) [substitution]
    *** source: 15494312-Fig-4e

Chemicals

  *** Rac1[Ab] GTP-association[BDPD] is increased irt Hgf (10 min)
    *** cells: MIMCD3 in BMLS
    *** inhibited by: U0126 [pretreatment]
    *** inhibited by: LY294002 [pretreatment]
    *** source: 15494312-Fig-4g

No extras

  *** Rac1[Ab] GTP-association[BDPD] is increased irt Hgf (times)
    *** cells: MDCK in BMS
    *** times: 0+ 5++ 15+++ 30++ 60+ min
    *** source: 10793146-Fig-2c
  *** xRac1[tAb] GTP-association[BDPD] is increased irt Hgf (times)
    *** cells: MDCK<xRac1> in BMS
    *** times: 0+ 5+ 15++ 30++ 60+ min
    *** source: 10793146-Fig-2b

