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Phosphorylation on S1981 S1983 S367 S2296
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Mre11--  ???

  *** Atm[Ab]IP phos(S1893)[phosAb] is unchanged irt IR (times)
    *** cells: ATLD6<Mre11~fmut> in BMS
    *** times: 0 15 60 min
    *** source: 16858402-Fig-4b
  *** Atm[Ab]IP phos(S367)[phosAb] is unchanged irt IR (times)
    *** cells: ATLD4<Mre11~fmut> in BMS
    *** times: 0 15++ 30+ min
    *** source: 21149446-Fig-6b
  *** Atm[Ab]IP phos(S1891)[phosAb] is unchanged irt IR (times)
    *** cells: ATLD4<Mre11~fmut> in BMS
    *** times: 0+ 15++ 30++ min
    *** source: 21149446-Fig-6b

Nbs1--  ???

  *** Atm[Ab]IP phos(S1893)[phosAb] is unchanged irt IR (times)
    *** cells: NBS03LA<Nbs1~fmut> in BMS
    *** times: 0 15 60 min
    *** source: 16858402-Fig-4a
  *** Atm[Ab]IP phos(S367)[phosAb] is unchanged irt IR (times)
    *** cells: NBS03LA<Nbs1~fmut> in BMS
    *** times: 0 15++ 30+ min
    *** source: 21149446-Fig-6a
  *** Atm[Ab]IP phos(S1891)[phosAb] is increased irt IR (times)
    *** cells: NBS03LA<Nbs1~fmut> in BMS
    *** times: 0+ 15++ 30++ min
    *** comment: the increase is significantly less than that seen in C3ABR
    *** source: 21149446-Fig-6a

Rad50--  ???

  *** Atm[Ab]IP phos(S367)[phosAb] is unchanged irt IR (times)
    *** cells: F239HTERT<Rad50~fmut> in BMS
    *** times: 0+ 15++ 30+ min
    *** source: 21149446-Fig-6c
  *** Atm[Ab]IP phos(S1893)[phosAb] is increased irt IR (60 min)
    *** cells: HA239<Rad50~fmut> in BMS
    *** comment: the increase is significantly less than that seen in C3ABR
    *** source: 16858402-Fig-4c

Atm kinase activity (AT1ABR contains a kinase dead mutant of Atm)

  *** Atm[Ab]IP phos(S1893)[phosAb] is unchanged irt IR (1 hr)
    *** cells: AT1ABR<Atm~fmut> in BMS
    *** source: 16858402-Fig-3c
  *** Atm[Ab]IP phos(S367)[phosAb] is unchanged irt IR (1 hr)
    *** cells: AT1ABR<Atm~fmut> in BMS
    *** source: 21149446-Fig-4c
  *** Atm[Ab]IP phos(S1891)[phosAb] is unchanged irt IR (1 hr)
    *** cells: AT1ABR<Atm~fmut> in BMS
    *** source: 21149446-Fig-4c
  *** Atm[Ab]IP phos(S1891)[phosAb] is unchanged irt IR (1 hr)
    *** cells: AT1ABR<Atm~fmut> in BMS
    *** source: 21149446-Fig-5b
  *** Atm[Ab]IP phos(S1893)[phosAb] is unchanged irt IR (1 hr)
    *** cells: AT1ABR<Atm~fmut> in BMS
    *** source: 21149446-Fig-4c
  *** Atm[Ab]IP phos(S2996)[phosAb] is unchanged irt IR (1 hr)
    *** cells: AT1ABR<Atm~fmut> in BMS
    *** source: 21149446-Fig-5b

chemicals

  *** Atm[Ab]IP phos(S1893)[phosAb] is increased irt IR (1 hr)
    *** cells: C3ABR in BMS
    *** inhibited by: KU55933 [pretreatment]
    *** source: 21149446-Fig-4a
  *** Atm[Ab]IP phos(S1893)[phosAb] is increased irt IR (1 hr)
    *** cells: C3ABR in BMS
    *** inhibited by: Wortmannin [pretreatment]
    *** source: 21149446-Fig-4b
  *** Atm[Ab]IP phos(S1893)[phosAb] is increased irt IR (1 hr)
    *** cells: C3ABR in BMS
    *** inhibited by: KU55933 [pretreatment]
    *** source: 16858402-Fig-3e
  *** Atm[Ab]IP phos(S1893)[phosAb] is increased irt IR (1 hr)
    *** cells: C3ABR in BMS
    *** partially inhibited by: Wortmannin [pretreatment]
    *** source: 16858402-Fig-3d
  *** Atm[Ab]IP phos(S367)[phosAb] is increased irt IR (1 hr)
    *** cells: C3ABR in BMS
    *** inhibited by: KU55933 [pretreatment]
    *** source: 21149446-Fig-4a
  *** Atm[Ab]IP phos(S367)[phosAb] is increased irt IR (1 hr)
    *** cells: C3ABR in BMS
    *** inhibited by: Wortmannin [pretreatment]
    *** source: 21149446-Fig-4b
  *** Atm[Ab]IP phos(S2996)[phosAb] is increased irt IR (1 hr)
    *** cells: C3ABR in BMS
    *** inhibited by: KU55933 [pretreatment]
    *** source: 21149446-Fig-5a

no extras

  *** Atm[Ab]IP phos(S1893)[phosAb] is increased irt IR (1 hr)
    *** cells: C3ABR in BMS
    *** source: 21149446-Fig-2a
  *** Atm[Ab]IP phos(S1893)[phosAb] is increased irt IR (times)
    *** cells: C3ABR in BMS
    *** times: 0 6+ 15+ 30+ 60+ 120+ 240+ 480+ 1440+ min
    *** source: 21149446-Fig-2b
  *** Atm[Ab]IP phos(S2996)[phosAb] is increased irt IR (1 hr)
    *** cells: C3ABR in BMS
    *** source: 21149446-Fig-3a
  *** Atm[Ab]IP phos(S2996)[phosAb] is increased irt IR (times)
    *** cells: C3ABR in BMS
    *** times: 0 6+ 15+ 30+ 60+ 120+ 240+ 480+ 1440 min
    *** source: 21149446-Fig-3b
  *** Atm[Ab]IP phos(S1893)[phosAb] is increased irt IR (1 hr)
    *** cells: C3ABR in BMS
    *** source: 16858402-Fig-3b
  *** Atm[Ab]IP phos(S1893)[phosAb] is increased irt IR (1 hr)
    *** cells: C3ABR in BMS
    *** source: 16858402-Fig-3c
  *** Atm[Ab]IP phos(S1893)[phosAb] is increased irt IR (60 min)
    *** cells: C3ABR in BMS
    *** source: 16858402-Fig-4c
  *** Atm[Ab]IP phos(S1893)[phosAb] is increased irt IR (times)
    *** cells: C3ABR in BMS
    *** times: 0 15+ 30+ 60++ 120++ 240++ 480++ 1440+ min
    *** source: 16858402-Fig-3a
  *** Atm[Ab]IP phos(S1893)[phosAb] is increased irt IR (times)
    *** cells: C3ABR in BMS
    *** times: 0+ 15++ 60+++ min
    *** source: 16858402-Fig-4a
  *** Atm[Ab]IP phos(S1893)[phosAb] is increased irt IR (times)
    *** cells: C3ABR in BMS
    *** times: 0+ 15++ 60+++ min
    *** source: 16858402-Fig-4b
  *** Atm[Ab]IP phos(S367)[phosAb] is increased irt IR (1 hr)
    *** cells: C3ABR in BMS
    *** source: 21149446-Fig-2a
  *** Atm[Ab]IP phos(S367)[phosAb] is increased irt IR (times)
    *** cells: C3ABR in BMS
    *** times: 0 6+ 15+ 30+ 60+ 120+ 240+ 480+ 1440+ min
    *** source: 21149446-Fig-2b
  *** Atm[Ab]IP phos(S367)[phosAb] is increased irt IR (times)
    *** cells: C3ABR in BMS
    *** times: 0 15++ 30+ min
    *** source: 21149446-Fig-6a
  *** Atm[Ab]IP phos(S367)[phosAb] is increased irt IR (times)
    *** cells: C3ABR in BMS
    *** times: 0 15++ 30+ min
    *** source: 21149446-Fig-6b
  *** Atm[Ab]IP phos(S367)[phosAb] is increased irt IR (times)
    *** cells: NFFHTERT in BMS
    *** times: 0+ 15++ 30+ min
    *** source: 21149446-Fig-6c



















