*** Accs--
  *** Accs[phosAb] phos(MSGLH)[phosAb] is decreased irt Tnf (16 hr)
    *** cells: L6 in BMLS "differentiated into myotubes"
    *** source: 17141630(D)
*** Ampkas--
  *** Ampkas[phosAb] phos(T172)[phosAb] is decreased irt Tnf (16 hr)
    *** cells: L6 in BMLS "differentiated into myotubes"
    *** partially reqs: Ppm1a [RNAi]
    *** source: 17141630(D)
  *** Ampkas[phosAb] phos(T172)[phosAb] is increased irt Tnf (times)
    *** cells: HELA in BMLS
    *** times: 0 2+ 5++ 10 min
    *** source: 16835226-Fig-8c
*** AP1-reporter--
  *** AP1-reporter[Luc] is increased irt Tnf (4 hr)
    *** cells: hUVECs in BMS
    *** inhibited by: Ebselen [pretreatment]
    *** source: 14720501-Fig-6a
  *** AP1-reporter[Luc] is increased irt Tnf (6 hr)
    *** cells: mEFs<Tak1~null><xTak1> in BMS
    *** reqs: xTak1 [omission]
    *** inhibited by: xTak1(K158R) [addition]
    *** source: 20038579-Fig-7e
  *** AP1-reporter[Luc] is increased irt Tnf (tnr)
    *** cells: SW480 in BMS
    *** reqs: Tnik [RNAi]
    *** source: 21710659-Fig-3b
*** Bag4--
  *** Bag4[Ab] copptby[WB] TnfR1[Ab] is decreased irt Tnf (5 min)
    *** cells: JURKAT<Pten~null> in BMS
    *** source: 9915703-Fig-4a
  *** Bag4[Ab] copptby[WB] TnfR1[Ab] is decreased irt Tnf (5 min)
    *** cells: U937 in BMS
    *** source: 9915703-Fig-4a
  *** Bag4[Ab] copptby[WB] TnfR1[Ab] is decreased irt Tnf (times)
    *** cells: JURKAT<Pten~null> in BMS
    *** times: 0+++ 2++ 5+ 10++ min
    *** source: 9915703-Fig-4b
  *** Bag4[Ab] copptby[WB] TnfR1[Ab] is decreased irt Tnf (times)
    *** cells: U937 in BMS
    *** times: 0+++ 2++ 5+ 10++ min
    *** source: 9915703-Fig-4b
*** Bcl2--
  *** Bcl2[Ab] prot-exp[WB] is unchanged irt Tnf (times)
    *** cells: mThyCs in BMS
    *** times: 0+ 10+ 20+ 30+ 60+ min
    *** does not req: Tnfaip3 [KO]
    *** source: 11009421-Fig-2c
*** Bcl2a1--
  *** Bcl2a1-gene mRNA[Northern] is increased irt Tnf (times)
    *** cells: U2OS in BMS
    *** times: 0 1+ 2++ hr
    *** inhibited by: xPias1 [addition]
    *** source: 15657437-Fig-2c
*** Bcl2l2--
  *** Bcl2l2-gene mRNA[RTPCR] is increased irt Tnf (12 hr)
    *** cells: THP1 in BMS
    *** reqs: Ampka1 [RNAi]
    *** source: 22833096-Fig-7c
*** Bcl3--
  *** Bcl3-gene mRNA[Northern] is increased irt Tnf (2 hr)
    *** cells: mLFs in BMS
    *** source: 15241416-Fig-1a
  *** Bcl3-gene mRNA[RTPCR] is increased irt Tnf (12 hr)
    *** cells: THP1 in BMS
    *** reqs: Ampka1 [RNAi]
    *** source: 22833096-Fig-S6
*** Bcl10--
  *** Bcl10-gene mRNA[RTPCR] is increased irt Tnf (times)
    *** cells: MCF7 in BMS
    *** times: 0+ 15++ 30+ 60+ min
    *** source: 16280327-Fig-3e
  *** Bcl10[Ab] copptby[WB] Akt1[Ab] is detectable-but unchanged irt Tnf (times)
    *** cells: MCF7 in BMS
    *** times: 0+ 15+ 30+ 60+ min
    *** source: 16280327-Fig-5b
*** Bclxl--
  *** Bclxl[Ab] prot-exp[WB] is unchanged irt Tnf (times)
    *** cells: mThyCs in BMS
    *** times: 0+ 10+ 20+ 30+ 60+ min
    *** does not req: Tnfaip3 [KO]
    *** source: 11009421-Fig-2c
*** Braf--
  *** Braf[phosAb] phos(T598/S601)[phosAb] is increased irt Tnf (10 min)
    *** cells: CCD18CO in BMLS
    *** reqs: Mlk3 [RNAi]
    *** source: 15258589-Fig-3b
*** Casp3--
  *** Casp3[Ab] cleavage[WB] is increased irt Tnf (6 hr)
    *** cells: HELA in BMS
    *** repressed by: Erc1 [RNAi]
    *** source: 15218148-Fig-3e
  *** Casp3[Ab] cleavage[WB] is increased irt Tnf (18 hr)
    *** cells: A431 in BMS "containing CHX"
    *** source: 11226410(D)
  *** Casp3[Ab] cleavage[WB] is unchanged irt Tnf (18 hr)
    *** cells: A431 in BMS
    *** source: 11226410(D)
*** Casp8--
  *** Casp8[Ab] cleavage[WB] is increased irt Tnf (times)
    *** cells: HT1080<xIkba(mnr)"DN"> in BMS
    *** times: 0 5 30+ 60++ 90++ 180+++ min
    *** comment: results represent Casp8 in Fadd-IP
    *** source: 16940186-Fig-4c
  *** Casp8[Ab] copptby[WB] Fadd[Ab] is increased irt Tnf (times)
    *** cells: HT1080<xIkba(mnr)"DN"> in BMS
    *** times: 0 5 30+ 60++ 90++ 180+ min
    *** source: 16940186-Fig-4c
  *** Casp8[Ab] copptby[WB] rTnf[tAb] is unchanged irt Tnf (times)
    *** cells: HT1080 in BMS
    *** times: 0 5 30 60 240 min
    *** unaffected by: xIkba(mnr)"degradation-deficient-mut" [addition]
    *** source: 12887920(D)
  *** Casp8[Ab]IP cleavage[WB] is increased irt Tnf (times)
    *** cells: HT1080 in BMS
    *** times: 0 5 30 60 120++ 240++ 480+ min
    *** source: 12887920(D)
  *** xCasp8[tAb]IP cleavage[WB] is increased irt Tnf (6 hr)
    *** cells: HEK293 in BMS
    *** source: 16585540-Fig-2a
*** Casp10--
  *** Casp10[Ab] cleavage[WB] is increased irt Tnf (times)
    *** cells: HT1080 in BMS
    *** times: 0 5 30 60 120+++ 240++ 480+ min
    *** comment: prolonged by xIkba(mnr)"degradation-deficient-mut" [addition]
    *** source: 12887920(D)
  *** Casp10[Ab] copptby[WB] Casp8[Ab] is increased irt Tnf (times)
    *** cells: HT1080 in BMS
    *** times: 0 5 30 60 120++ 240+ 480 min
    *** comment: prolonged by xIkba(mnr)"degradation-deficient-mut" [addition]
    *** source: 12887920(D)
*** CcL2--
*** CcL5--
  *** CcL5[Ab] secretion[ELISA] is increased irt Tnf (24 hr)
    *** cells: hBSMCs in BMS
    *** unaffected by: Tnf [cotreatment]
    *** source: 17541284-Fig-1d
  *** CcL8-gene mRNA[RTPCR] is increased irt Tnf (4 hr)
    *** cells: mEFs<Rela~null><xRela> in BMS
    *** reqs: xRela [omission]
    *** unaffected by: xRela(S468A) [substitution]
    *** source: 16046471-Fig-5c
*** CcL11--
  *** CcL11-gene mRNA[RTPCR] is increased irt Tnf (24 hr)
    *** cells: hBSMCs in BMS
    *** source: 17541284-Fig-2
  *** CcL11-gene mRNA[RTPCR] is increased irt Tnf (times)
    *** cells: hFibros in BMS
    *** times: 0 2+ 8+ 24+ 48+ hr
    *** source: 11544308-Fig-3
  *** CcL11-gene promo-reporter[Luc] is unchanged irt Tnf (20 hr)
    *** cells: hBSMCs in BMS
    *** source: 17541284-Fig-4
  *** CcL11[Ab] secretion[ELISA] is unchanged irt Tnf (24 hr)
    *** cells: hBSMCs in BMS
    *** source: 17541284-Fig-1a
  *** CcL11-gene mRNA[RTPCR] is increased irt Tnf (72 hr)
    *** cells: mEFs in BMS
    *** source: 14733929-Fig-1b
  *** CcL11[Ab] secretion[ELISA] is increased irt Tnf (72 hr)
    *** cells: mEFs in BMS
    *** does not req: Stat6 [KO]
    *** source: 14733929-Fig-4
  *** CcL11[Ab] secretion[ELISA] is increased irt Tnf (72 hr)
    *** cells: mEFs in BMS
    *** inhibited by: xSocs1 [addition]
    *** source: 14733929-Fig-6b
  *** CcL11[Ab] secretion[ELISA] is increased irt Tnf (72 hr)
    *** cells: mEFs in BMS
    *** source: 14733929-Fig-1a
  *** CcL11-gene mRNA[RTPCR] is increased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0 2 4 8+ 12+ 24++ 36++ hr
    *** unaffected by: Ifng [cotreatment]
    *** source: 14733929-Fig-2
*** CcL13--
  *** CcL13[Ab] secretion[ELISA] is unchanged irt Tnf (24 hr)
    *** cells: hBSMCs in BMS
    *** source: 17541284-Fig-1c
*** CcL26--
  *** CcL26-gene mRNA[RTPCR] is unchanged irt Tnf (times)
    *** cells: hFibros in BMS
    *** times: 0 2 8 24 48 hr
    *** source: 11544308-Fig-3
  *** CcL26[Ab] secretion[ELISA] is unchanged irt Tnf (24 hr)
    *** cells: hBSMCs in BMS
    *** source: 17541284-Fig-1b
  *** CcL26[Ab] secretion[ELISA] is unchanged irt Tnf (times)
    *** cells: hFibros in BMS
    *** times: 0 2 8 24 48 hr
    *** source: 11544308-Fig-3
  *** CcL26[Ab] secretion[ELISA] is unchanged irt Tnf (tnr)
    *** cells: HEK293<xStat6> in BMS
    *** source: 11544308-Fig-9
  *** Cd44-gene mRNA[RTPCR] is increased irt Tnf (12 hr)
    *** cells: THP1 in BMS
    *** reqs: Ampka1 [RNAi]
    *** source: 22833096-Fig-6b
*** Cd54--
  *** Cd54[Ab] surface-exp[FACS] is increased irt Tnf (48 hr)
    *** cells: mEFs in BMS
    *** does not req: Jak1 [KO]
    *** source: 9590172-Fig-2e
*** Cebpb--
  *** Cebpb[Ab] infraction(nuclear)[WB] is detectable-but unchanged irt Tnf (times)
    *** cells: mSPImacs in BMS
    *** times: 0+ 10+ 30+ 60+ min
    *** source: 19733238-Fig-2c
*** Cezanne--
*** Ciap1--
*** Ciap1--
  *** Ciap1[Ab] cleavage[WB] is increased irt Tnf (times)
    *** cells: HT1080 in BMS
    *** times: 0 5 30 60 120+++ 240++ 480+ min
    *** inhibited by: xIkba(mnr)"degradation-deficient-mut" [addition]
    *** source: 12887920(D)
  *** Ciap1[Ab] copptby[WB] Casp8[Ab] is increased irt Tnf (times)
    *** cells: HT1080 in BMS
    *** times: 0 5 30 60+ 120++ 240++ 480+ min
    *** source: 12887920-Fig-4a
  *** Ciap1[Ab] copptby[WB] Traf2[Ab] is detectable-but unchanged irt Tnf (5 min)
    *** cells: HELA in BMS
    *** source: 8943045-Fig-5
  *** Ciap1[Ab] copptby[WB] Ubc13[Ab] is increased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0 15+ 30+ 45 60 90 120 240 min
    *** comment: decrease after 30 min requires Tax1bp1 [KO]
    *** source: 20185725-Fig-S1c
  *** Ciap1[Ab] prot-exp[WB] is unchanged irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 10+ 20+ 30+ 60+ 90+ 120+ 180+ min
    *** does not req: Tnfaip3 [KO]
    *** source: 11009421-Fig-2c
*** Ciap2--
  *** Ciap2-gene promo-reporter[Luc] is increased irt Tnf (36 hr)
    *** cells: mEFs in BMS
    *** does not req: Tpl2 [KO]
    *** source: 15670770-Fig-1f
*** Csnk2--
  *** Csnk2[Ab] copptby[WB] xRela[tAb] is decreased irt Tnf (times)
    *** cells: mEFs<Rela~null><xRela> in BMS
    *** times: 0++ 5++ 15+ 60+ min
    *** inhibited by: xRela(F529A) [substitution]
    *** source: 10938077-Fig-1b
*** CxcL1--
*** CxcL2--
*** CxcL10--
*** E2f1--
  *** E2f1[Ab] oligo-binding[EMSA] is unchanged irt Tnf (15 min)
    *** cells: MCF7 in BMS
    *** source: 15657437-Fig-7a
*** EgfR--
*** EgfR--
  *** EgfR[Ab] cleavage[WB] is increased irt Tnf (18 hr)
    *** cells: A431 in BMS "containing CHX"
    *** source: 11226410(D)
  *** EgfR[Ab] cleavage[WB] is unchanged irt Tnf (18 hr)
    *** cells: A431 in BMS
    *** source: 11226410(D)
  *** EgfR[Ab]IP surface-exp[FACS] is decreased irt Tnf (15 min)
    *** cells: HELA in BMS
    *** reversed by: SB203580 [pretreatment]
    *** source: 19687304-Fig-5c
  *** EgfR[phosAb] phos(Y869)[phosAb] is unchanged irt Tnf (times)
    *** cells: HELA in BMS
    *** times: 0 5 10 min
    *** source: 19687304-Fig-1a
  *** EgfR[phosAb] phos(Y998)[phosAb] is unchanged irt Tnf (times)
    *** cells: HELA in BMS
    *** times: 0 5 10 min
    *** source: 19687304-Fig-1a
  *** EgfR[phosAb] phos(Y1092)[phosAb] is unchanged irt Tnf (times)
    *** cells: HELA in BMS
    *** times: 0 5 10 min
    *** source: 19687304-Fig-1a
  *** EgfR[phosAb] phos[WBMS] is increased irt Tnf (10 min)
    *** cells: HELA in BMS
    *** inhibited by: 5Z7Oxozeaenol [pretreatment]
    *** unaffected by: PD153035 [pretreatment]
    *** source: 19687304-Fig-1c
  *** EgfR[phosAb] phos[WBMS] is increased irt Tnf (10 min)
    *** cells: HELA in BMS
    *** reqs: Tak1 [RNAi]
    *** source: 19687304-Fig-1b
  *** EgfR[phosAb] phos[WBMS] is increased irt Tnf (times)
    *** cells: HELA in BMS
    *** times: 0 5+ 10+ min
    *** source: 19687304-Fig-1a
  *** xEgfR[XFP] locatedin(vesicles)[IHC] is increased irt Tnf (15 min) 
    *** cells: HELA<xEgfR> in BMS
    *** inhibited by: 5Z7Oxozeaenol [pretreatment]
    *** unaffected by: PD153035 [pretreatment]
    *** source: 19687304-Fig-1e
  *** xEgfR[XFP] locatedin(vesicles)[IHC] is increased irt Tnf (15 min) 
    *** cells: HELA<xEgfR> in BMS
    *** inhibited by: SB203580 [pretreatment]
    *** unaffected by: U0126 [pretreatment]
    *** source: 19687304-Fig-5a
*** Egr1--
*** Eif4e--
*** Eif4ebp1--
  *** Eif4ebp1[Ab] phos[WBMS] is increased irt Tnf (60 min)
    *** cells: MKN74 in BMS
    *** partially inhibited by: Rapamycin [pretreatment]
    *** source: 11352916-Fig-8c
  *** Eif4ebp1[phosAb] phos(S65)[phosAb] is increased irt Tnf (times)
    *** cells: MCF7 in BMLS
    *** times: 0 5+ 10++ 20++ 30++ min
    *** source: 17693255-Fig-1a
  *** Eif4ebp1[phosAb] phos(S65)[phosAb] is increased irt Tnf (times)
    *** cells: MDAMB453 in BMLS
    *** times: 0+ 5++ 10++ 20+ 30+ min
    *** source: 17693255-Fig-1a
*** Erc1--
  *** Erc1[Ab]IP IVKA(Ikba)[32P-ATP] is increased irt Tnf (7 min)
    *** cells: HELA in BMS
    *** source: 15218148-Fig-1d
  *** Erk1-gene mRNA[RTPCR] is unchanged irt Tnf (24 hr)
    *** cells: 3T3L1 in BMS "differentiated into adipocytes"
    *** source: 17500068-Fig-2
  *** Erk2-gene mRNA[RTPCR] is unchanged irt Tnf (24 hr)
    *** cells: 3T3L1 in BMS "differentiated into adipocytes"
    *** source: 17500068-Fig-2
*** Erk5--
  *** Erk5[Ab] phos[WBMS] is unchanged irt Tnf (20 min)
    *** cells: HELA in BMLS
    *** source: 9790194-Fig-1a
  *** Erk5[Ab]IP IVKA(Mef2c)[32P-ATP] is unchanged irt Tnf (20 min)
    *** cells: HELA in BMLS
    *** source: 9790194-Fig-1a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Tnf (times)
    *** cells: HACAT in BMLS
    *** times: 0 5 15+ 30+ 60 120 min
    *** source: 18675783-Fig-4a
*** Eselectin--
*** Fadd--
  *** Fadd[Ab] copptby[WB] Casp8[Ab] is increased irt Tnf (times)
    *** cells: HT1080 in BMS
    *** times: 0 5 30 60++ 120++ 240++ 480+ min
    *** comment: prolonged by xIkba(mnr)"degradation-deficient-mut" [addition]
    *** source: 12887920-Fig-4a
  *** Fadd[Ab] copptby[WB] Tnf[Flag] is unchanged irt Tnf (times)
    *** cells: HT1080 in BMS
    *** times: 0 5 30 60 240 min
    *** unaffected by: xIkba(mnr)"degradation-deficient-mut" [addition]
    *** source: 12887920(D)
  *** Fadd[Ab] copptby[WB] TnfR1[Ab] is increased irt Tnf (10 min)
    *** cells: JURKAT<Pten~null> in BMS
    *** reqs: Tradd [RNAi]
    *** source: 16611992-Fig-5d
*** Flip--
  *** Flip[Ab] cleavage[WB] is increased irt Tnf (times)
    *** cells: HT1080 in BMS
    *** times: 0 5 30 60+ 120++ 240++ 480+++ min
    *** enhanced by: xIkba(mnr)"degradation-mut" [addition]
    *** source: 12887920(D)
  *** Flip[Ab] copptby[WB] Casp8[Ab] is increased irt Tnf (times)
    *** cells: HT1080 in BMS
    *** times: 0 5 30 60+ 120++ 240++ 480+++ min
    *** inhibited by: xIkba(mnr)"degradation-deficient-mut" [addition]
    *** source: 12887920(D)
  *** Flip[Ab] copptby[WB] Casp8[Ab] is increased irt Tnf (times)
    *** cells: HT1080 in BMS
    *** times: 0 16+ hr
    *** inhibited by: xIkba(mnr)"degradation-deficient-mut" [addition]
    *** source: 12887920(D)
  *** Flip[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: C2C12<xCiap1(mnr)"KD"> in BMS
    *** times: 0+ 5+ 15+ 30 60 min
    *** source: 18697935-Fig-2b
  *** Flip[Ab] prot-exp[WB] is unchanged irt Tnf (times)
    *** cells: C2C12 in BMS
    *** times: 0+ 5+ 15+ 30+ 60+ min
    *** source: 18697935-Fig-2b
*** Fos--
  *** Foxo13s[phosAb] phos(CTWPL)[phosAb] is increased irt Tnf (30 min)
    *** cells: mEFs in BMLS
    *** partially reqs: Ikke and/or Tbk1 [KO]
    *** source: 21464307-Fig-2b
*** Gbp1--
  *** Gbp1-gene promo-reporter[Luc] is increased irt Tnf (4 hr)
    *** cells: mEFs in BMLS
    *** cells: mEFs<Pkr~null><xPkr> in BMLS
    *** does not req: xPkr [omission]
    *** unaffected by: xPkr(K296R)"KD" [addition]
    *** source: 9029059-Fig-6b
  *** Gbp1-gene promo-reporter[Luc] is increased irt Tnf (4 hr)
    *** cells: mEFs in BMLS
    *** unaffected by: xPkr [addition]
    *** partially inhibited by: xPkr(K296R)"KD" [addition]
    *** source: 9029059-Fig-6a
  *** Gsk3b[phosAb] phos(S9)[phosAb] is unchanged irt Tnf (times)
    *** cells: MDAMB453 in BMLS
    *** times: 0 5 10 20 30 min
    *** source: 17693255-Fig-S1c
*** Gsk3s--
  *** Gsk3s[phosAb] phos(SFAE)[phosAb] is increased irt Tnf (30 min)
    *** cells: mEFs in BMLS
    *** bkg reqs: Ikke and/or Tbk1 [KO]
    *** source: 21464307-Fig-2b
*** Hif1a--
  *** Hif1a-gene mRNA[Northern] is increased irt Tnf (3 hr)
    *** cells: hSNFs in BMLS
    *** source: 10926858-Fig-2
  *** Hif1a-gene mRNA[Northern] is unchanged irt Tnf (4 hr)
    *** cells: HEPG2 in BMS
    *** source: 10477681-Fig-5
  *** Hif1a-gene mRNA[RTPCR] is unchanged irt Tnf (8 hr)
    *** cells: LLCPK1 in BMS
    *** unaffected by: Sulfasalazine [pretreatment]
    *** source: 12808024-Fig-7
  *** Hif1a-gene mRNA[RTPCR] is unchanged irt Tnf (8 hr)
    *** cells: LLCPK1 in BMS
    *** unaffected by: xIkba(mnr)"DN" [addition]
    *** source: 12808024-Fig-7
  *** Hif1a-gene mRNA[RTPCR] is unchanged irt Tnf (8 hr)
    *** cells: LLCPK1 in BMS
    *** unaffected by: xNfkb1(1-433) + xRela [addition]
    *** source: 12808024-Fig-7
  *** Hif1a[Ab] oligo-binding[EMSA] is increased irt Tnf (6 hr)
    *** cells: LLCPK1 in BMS
    *** source: 11514583-Fig-7
  *** Hif1a[Ab] prot-exp[ELISA] is increased irt Tnf (times)
    *** cells: hUVECs in BMS
    *** times: 0 4+ 24 hr
    *** source: 18606657-Fig-1a
  *** Hif1a[Ab] prot-exp[IHC] is increased irt Tnf (16 hr)
    *** cells: LLCPK1 in BMS
    *** source: 12808024-Fig-1a
  *** Hif1a[Ab] prot-exp[WB] is increased irt Tnf (2 hr)
    *** cells: mEFs in BMS
    *** bkg reqs: Ripk1 [KO]
    *** source: 12479793-Fig-2a
  *** Hif1a[Ab] prot-exp[WB] is increased irt Tnf (4 hr)
    *** cells: A549 in BMS
    *** source: 12479793-Fig-4a
  *** Hif1a[Ab] prot-exp[WB] is increased irt Tnf (4 hr)
    *** cells: HEK293 in BMS
    *** source: 12479793-Fig-4a
  *** Hif1a[Ab] prot-exp[WB] is increased irt Tnf (4 hr)
    *** cells: MCF7 in BMS
    *** source: 12479793-Fig-4a
  *** Hif1a[Ab] prot-exp[WB] is increased irt Tnf (6 hr)
    *** cells: LLCPK1 in BMS
    *** inhibited by: DMNQ [cotreatment]
    *** source: 11514583-Fig-2b
  *** Hif1a[Ab] prot-exp[WB] is increased irt Tnf (6 hr)
    *** cells: LLCPK1 in BMS
    *** inhibited by: Genistein [pretreatment] no-bkg-control
    *** source: 11514583-Fig-3b
  *** Hif1a[Ab] prot-exp[WB] is increased irt Tnf (6 hr)
    *** cells: LLCPK1 in BMS
    *** inhibited by: Wortmannin [pretreatment]
    *** source: 11514583-Fig-4b
  *** Hif1a[Ab] prot-exp[WB] is increased irt Tnf (8 hr)
    *** cells: LLCPK1 in BMS
    *** comment: prot-exp is decreased by addition of CHX after Tnf
    *** source: 12808024-Fig-8a
  *** Hif1a[Ab] prot-exp[WB] is increased irt Tnf (8 hr)
    *** cells: LLCPK1 in BMS
    *** inhibited by: ActinomycinD [pretreatment]
    *** source: 12808024-Fig-4a
  *** Hif1a[Ab] prot-exp[WB] is increased irt Tnf (16 hr)
    *** cells: LLCPK1 in BMS
    *** inhibited by: Sulfasalazine [pretreatment]
    *** source: 12808024-Fig-5a
  *** Hif1a[Ab] prot-exp[WB] is increased irt Tnf (16 hr)
    *** cells: LLCPK1 in BMS
    *** inhibited by: xAkt1(K179A) [addition]
    *** source: 11514583-Fig-6c
  *** Hif1a[Ab] prot-exp[WB] is increased irt Tnf (16 hr)
    *** cells: LLCPK1 in BMS
    *** inhibited by: xIkba(mnr)"DN" [addition]
    *** unaffected by: xIkba [addition]
    *** source: 12808024-Fig-5b
  *** Hif1a[Ab] prot-exp[WB] is increased irt Tnf (16 hr)
    *** cells: LLCPK1 in BMS
    *** inhibited by: xPik3r1(del(479-513)) [addition]
    *** source: 11514583-Fig-5c
  *** Hif1a[Ab] prot-exp[WB] is increased irt Tnf (16 hr)
    *** cells: LLCPK1 in BMS
    *** partially inhibited by: xNfkb1(1-433) + xRela [addition]
    *** source: 12808024-Fig-6
  *** xHif1a[Ab] prot-exp[WB] is increased irt Tnf (times)
    *** cells: HEK293<xHif1a> in BMS
    *** times: 0 4+ 8+++ 12++ 16++ 20+ 24+ hr
    *** source: 12808024-Fig-1b
  *** xHif1a[Ab] prot-exp[WB] is increased irt Tnf (times)
    *** cells: HEK293<xHif1a> in BMS
    *** times: 0+ 4++ 8++ 16++ hr
    *** source: 12808024-Fig-3a
  *** Hif1a[Ab] prot-exp[WB] is increased irt Tnf (times)
    *** cells: LLCPK1 in BMS
    *** times: 0 2+ 6++ 10+++ 14+++ 18+++ 24 hr
    *** source: 11514583-Fig-1b
  *** Hif1a[Ab] prot-exp[WB] is increased irt Tnf (times)
    *** cells: NIH3T3 in BMS
    *** times: 0 2+ 4+ 6 hr
    *** source: 12479793-Fig-1a
  *** Hif1a[Ab] prot-exp[WB] is increased irt Tnf (times)
    *** cells: rA2ECs in BMS
    *** times: 0 15+ 30++ 60++ 120++ 240++ 480++ 960++ 1440+ 2880+ 4320 5760 min
    *** source: 11566189-Fig-1
  *** Hif1a[Ab] prot-exp[WB] is increased irt Tnf (tnr)
    *** cells: NIH3T3 in BMS
    *** inhibited by: ActinomycinD [addition] no-bkg-control
    *** source: 12479793-Fig-1b
  *** Hif1a[Ab] prot-exp[WB] is unchanged irt Tnf (tnr)
    *** cells: HEPG2 in BMS "nuclear-extracts"
    *** source: 10477681-Fig-3
  *** Hif1a[Ab] prot-stability[CHX-WB] is unchanged irt Tnf (tnr)
    *** cells: NIH3T3 in BMS
    *** source: 12479793-Fig-1d
  *** xHif1a[Ab] ubiq[tUbAb-ppt] is increased irt Tnf (times)
    *** cells: HEK293<xHif1a><xUbiq> in BMS
    *** times: 0 4+ 8++ 12++ 16++ 20++ 24+ hr
    *** source: 12808024-Fig-1b
  *** HRE-reporter[Luc] is increased irt Tnf (16 hr)
    *** cells: LLCPK1 in BMS
    *** source: 11514583-Table-1
*** Hsp90--
  *** Hsp90[Ab] copptby[WB] TnfR1[Ab] is increased irt Tnf (5 min)
    *** cells: HELA in BMS
    *** inhibited by: Geldanamycin [addition]
    *** source: 11864612-Fig-6c
*** Hspb1--
  *** Hspb1[phosAb] phos(S82)[phosAb] is unchanged irt Tnf (30 min)
    *** cells: mEFs in BMLS
    *** does not req: Mnk1 and/or Mnk2 [DKO]
    *** source: 15254222-Fig-3a
  *** Iceberg-gene mRNA[Northern] is increased irt Tnf (times)
    *** cells: THP1 in BMS
    *** times: 0 2 6+ 12 hr
    *** source: 11051551(D)
  *** Iceberg-gene mRNA[Northern] is increased irt Tnf (tnr)
    *** cells: hUVECs in BMS
    *** source: 11051551(D)
  *** Ier3-gene mRNA[Northern] is increased irt Tnf (times)
    *** cells: mEFs in BMS "on gelatin"
    *** times: 0 15 60++ 120 min
    *** source: 14636585(D)
  *** Ier3-gene mRNA[Northern] is increased irt Tnf (times)
    *** cells: mEFs<Ikba~null> in BMS
    *** times: 0 15 60 120+ min
    *** source: 14636585(D)
  *** Ier3-gene mRNA[Northern] is increased irt Tnf (times)
    *** cells: mEFs<Mekk3~null> in BMS
    *** times: 0 15 60 120+ min
    *** source: 14636585(D)
  *** Ier3-gene mRNA[RTPCR] is increased irt Tnf (12 hr)
    *** cells: THP1 in BMS
    *** partially reqs: Ampka1 [RNAi]
    *** source: 22833096-Fig-S6
  *** Ifnb1-gene mRNA[RTPCR] is unchanged irt Tnf (times)
    *** cells: mBMDCs in BMS
    *** times: 0 1 2 4 6 hr
    *** unaffected by: Ifng (4 hr) [pretreatment]
    *** source: 17018642-Fig-6
*** Ifng--
  *** Ifng-gene mRNA[RPA] is unchanged irt Tnf (4 hr)
    *** cells: mBMNKs<Rag1~null> in BMS
    *** source: 10229825-Fig-1b
  *** Ifng[Ab] secretion[ELISA] is unchanged irt Tnf (4 hr)
    *** cells: mBMNKs<Rag1~null> in BMS
    *** source: 10229825-Fig-1a
*** Ikba--
  *** Ikba[Ab] upshift[WBMS] is increased irt Tnf (times)
    *** cells: HELA in BMS "pretreated with Z-LLF-CHO"
    *** times: 0 5+ 10++ 15++ 20 min
    *** source: 8657102-Fig-6a
  *** xIkba[tAb] upshift[WBMS] is increased irt Tnf (times)
    *** cells: HELA in BMS "pretreated with Z-LLF-CHO"
    *** times: 0 5+ 10+ 15+ 20+ min
    *** inhibited by: xIkba(S32A/S36A) [substitution]
    *** source: 8657102-Fig-6a
  *** xIkba[tAb]IP ubiq[UbAb] is increased irt Tnf (12 min)
    *** cells: HELA in BMS "pretreated with Z-LLF-CHO"
    *** inhibited by: xIkba(S32A/S36A) [substitution]
    *** source: 8657102-Fig-6b
  *** xIkba[tAb]IP upshift[WBMS] is increased irt Tnf (12 min)
    *** cells: HELA in BMS "pretreated with Z-LLF-CHO"
    *** inhibited by: xIkba(S32A/S36A) [substitution]
    *** source: 8657102-Fig-6b
  *** xIkba[tAb]IP upshift[WBMS] is increased irt Tnf (12 min)
    *** cells: HELA in BMS "pretreated with Z-LLF-CHO"
    *** partially inhibited by: xIkba(K21R/K22R) [substitution]
    *** source: 8657102-Fig-6b
  *** Ikba{phos}[phosAb] upshift[WBMS] is increased irt Tnf (5 min)
    *** cells: HELA in BMS
    *** does not req: Usp21 [RNAi]
    *** source: 19910467-Fig-4b
*** Ikbb--
  *** Ikbb[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0++ 15+ 30+ 60 120 240+ min
    *** partially reqs: Pkr [KO]
    *** source: 10648614-Fig-3
  *** Ikbb[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: T98G in BMS
    *** times: 0+ 12+ 30 60 90 120 240 min
    *** source: 10648614-Fig-2a
*** Ikk1--
  *** Ikk1[Ab] copptby[WB] xPpp2cb[tAb] is decreased irt Tnf (times)
    *** cells: HEK293 in BMS
    *** times: 0+ 5+ 15 30+ 60+ min
    *** source: 14585847-Fig-1b
  *** Ikk1[Ab] infraction(nuclear)[WB] is detectable-but unchanged irt Tnf (30 min)
    *** cells: mEFs in BMS
    *** source: 19666475-Fig-5f
  *** xIkk1[Ab] infraction(nuclear)[WB] is detectable-but unchanged irt Tnf (30 min)
    *** cells: mEFs<Ikk1~null><xIkk1> in BMS
    *** unaffected by: xIkk1(1-737)"delNBD" [substitution]
    *** source: 19666475-Fig-5f
  *** Ikk1[Ab]IP IVKA(Nfkb2)[32P-ATP] is unchanged irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0 15 180 min
    *** source: 12387745-Fig-6b
  *** Ikk2[Ab] infraction(nuclear)[WB] is unchanged irt Tnf (30 min)
    *** cells: mEFs in BMS
    *** source: 19666475-Fig-5f
  *** Ikk2[Ab] infraction(nuclear)[WB] is unchanged irt Tnf (30 min)
    *** cells: mEFs<Ikk1~null><xIkk1> in BMS
    *** unaffected by: xIkk1(1-737)"delNBD" [substitution]
    *** source: 19666475-Fig-5f
  *** Ikke[Ab]IP prot-exp[WB] is increased irt Tnf (24 hr)
    *** cells: HELA in BMS
    *** source: 17003035-Fig-2d
*** IL1b--
*** IL6--
*** IL8--
  *** IL12a-gene mRNA[RTPCR] is unchanged irt Tnf (times)
    *** cells: mBMDCs in BMS
    *** times: 0 1 2 4 6 hr
    *** unaffected by: Ifng (4 hr) [pretreatment]
    *** source: 17018642-Fig-6
  *** IL13Ra1-gene mRNA[RTPCR] is unchanged irt Tnf (8 hr)
    *** cells: HACAT in BMS
    *** source: 12776189-Fig-1b
  *** IL13Ra2-gene mRNA[RTPCR] is unchanged irt Tnf (8 hr)
    *** cells: HACAT in BMS
    *** source: 12776189-Fig-1a
  *** IL13Ra2[Ab] surface-exp[FACS] is unchanged irt Tnf (24 hr)
    *** cells: HACAT in BMS
    *** source: 12776189-Fig-1c
*** Irak1--
  *** Irak1[Ab] upshift[WBMS] is unchanged irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0 15 30 min
    *** source: 17337443-Fig-3c
*** Irak4--
  *** Irak4[Ab] phos[WBMS] is unchanged irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0 15 30 min
    *** source: 17337443-Fig-3c
*** Irf1--
*** Irf3--
  *** Irf3[Ab] oligomerization[NativeWB] is unchanged irt Tnf (1 hr)
    *** cells: U373 in BMS
    *** source: 12062447-Fig-1a
*** Irs1--
  *** Irs1[phosAb] phos(S307)[phosAb] is increased irt Tnf (times)
    *** cells: MDAMB453 in BMLS
    *** times: 0+ 10++ 20++ 30+++ min
    *** source: 18949383-Fig-1a
  *** Irs1[phosAb] phos(S636/S639)[phosAb] is increased irt Tnf (times)
    *** cells: MDAMB453 in BMLS
    *** times: 0+ 10++ 20++ 30++ min
    *** source: 18949383-Fig-1a
*** Itch--
  *** Jnk1-gene mRNA[RTPCR] is unchanged irt Tnf (24 hr)
    *** cells: 3T3L1 in BMS "differentiated into adipocytes"
    *** source: 17500068-Fig-2
  *** Jnk2-gene mRNA[RTPCR] is unchanged irt Tnf (24 hr)
    *** cells: 3T3L1 in BMS "differentiated into adipocytes"
    *** source: 17500068-Fig-2
  *** Jnks[phosAb] phos(TPY)[phosAb] is increased irt Tnf (times)
    *** cells: HACAT in BMLS
    *** times: 0 5 15+ 30+ 60 120 min
    *** source: 18675783-Fig-4a
*** Jun--
*** Junb--
  *** Kpna3[Ab] copptby[WB] Nfkb1[Ab] is increased irt Tnf (30 min)
    *** cells: A549 in BMS
    *** source: 15677444-Fig-2a
  *** Kpna3[Ab] copptby[WB] Rela[Ab] is increased irt Tnf (30 min)
    *** cells: A549 in BMS
    *** source: 15677444-Fig-2a
*** Lkb1--
  *** Lkb1[phosAb] phos(S428)[phosAb] is increased irt Tnf (tnr)
    *** cells: B16F1 in BMLS
    *** source: 19274086-Fig-2a
  *** Lkb1[phosAb] phos(S428)[phosAb] is increased irt Tnf (tnr)
    *** cells: MEWO in BMLS
    *** source: 19274086-Fig-2a
  *** Lkb1[phosAb] phos(S428)[phosAb] is unchanged irt Tnf (tnr)
    *** cells: 3731T in BMLS
    *** source: 19274086-Fig-2a
*** Map4k4--
  *** xMap4k4[tAb]IP IVKA(MBP)[32P-ATP] is increased irt Tnf (times)
    *** cells: HEK293T<xMap4k4> in BMS
    *** times: 0 1+ 5++ 10+ 30+ 60+ min
    *** source: 9890973-Fig-8a
*** Mapkapk2--
*** Mek1--
  *** Mek1[phosAb] phos(S218/S222)[phosAb] is unchanged irt Tnf (10 min)
    *** cells: CCD18CO in BMLS
    *** source: 15258589-Fig-2a
*** Mek12s--
  *** Mek12s[phosAb] phos(sitenr)[phosAb] is unchanged irt Tnf (times)
    *** cells: 3DO in BMS
    *** times: 0+ 5+ 10+ 20+ 40+ 80+ 160+ min
    *** unaffected by: xIkba(S32A/S36A/S283A/S288A/T291A/S293A/T296A)"DN" [addition]
    *** source: 14743220-Fig-2d
*** Mkk3--
  *** Mkk3[Ab]IP IVKA(P38a)[32P-ATP] is increased irt Tnf (10 min)
    *** cells: HEK293 in BMS
    *** comment: unaffected by rGadd45b in IVKA
    *** source: 14743220-Fig-3e
*** Mkk36s--
  *** Mkk36s[phosAb] phos(sitenr)[phosAb] is increased irt Tnf (times)
    *** cells: 3DO in BMS
    *** times: 0+ 5++ 10+ 20+ 40+ 80+ 160+ min
    *** unaffected by: xIkba(S32A/S36A/S283A/S288A/T291A/S293A/T296A)"DN" [addition]
    *** source: 14743220-Fig-2d
  *** Mtor[Ab]IP IVKA(Eif4ebp1)[32P-ATP] is increased irt Tnf (30 min)
    *** cells: MCF7 in BMLS
    *** source: 17693255-Fig-1b
*** Nemo--
  *** Nemo[Ab] infraction(nuclear)[WB] is detectable-but unchanged irt Tnf (30 min)
    *** cells: mEFs in BMS
    *** source: 19666475-Fig-5f
  *** Nemo[Ab] infraction(nuclear)[WB] is detectable-but unchanged irt Tnf (30 min)
    *** cells: mEFs<Ikk1~null><xIkk1> in BMS
    *** inhibited by: xIkk1(1-737)"delNBD" [substitution]
    *** source: 19666475-Fig-5f
  *** Nemo[Ab]IP IVKA(Tank)[32P-ATP] is increased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0 5+ 10+ 20 30 min
    *** reqs: Ripk1 [KO]
    *** source: 16336209-Fig-4d
  *** Nemo[Ab]IP IVKA(Tank)[32P-ATP] is increased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0 5+ 15++ 30+ 60 min
    *** does not req: Traf2 [KO]
    *** source: 16336209-Fig-4c
  *** Nemo[Ab]IP IVKA(Tank)[32P-ATP] is increased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0 5++ 10++ 20+ 30+ min
    *** comment: Tank phos is delayed by 5 min in TnfR2 KO mEFs
    *** source: 16336209-Fig-4b
  *** Nemo[Ab]IP IVKA(Tank)[32P-ATP] is increased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0 15+ 30++ min
    *** does not req: Ikk1 [KO]
    *** source: 16336209-Fig-3b
  *** Nemo[Ab]IP IVKA(Tank)[32P-ATP] is increased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0 15+ 30++ min
    *** reqs: Ikk1 and/or Ikk2 [DKO]
    *** source: 16336209-Fig-3a
  *** Nemo[Ab]IP IVKA(Tank)[32P-ATP] is increased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0 15+ 30++ min
    *** reqs: Ikk2 [KO]
    *** source: 16336209-Fig-3b
  *** xNemo[Ab]IP phos(S85)[phosAb] is unchanged irt Tnf (30 min)
    *** cells: HEK293<xNemo> in BMS
    *** source: 16497931-Fig-2b
  *** Nemo[Ab]IP phos(S85)[phosAb] is unchanged irt Tnf (30 min)
    *** cells: hLymphoblasts in BMS
    *** source: 16497931-Fig-2d
  *** xNemo[tAb]IP sumo[tSuAb] is unchanged irt Tnf (times)
    *** cells: HEK293<xNemo><xSumo1> in BMS
    *** times: 0 30 60 120 min
    *** source: 14651848-Fig-1b
*** Nfkb--
  *** Nfkb-reporter[Luc] is increased irt Tnf (5 hr)
    *** cells: mEFs in BMS
    *** reqs: Ikk1 [KO]
    *** source: 19666475-Fig-5d
  *** Nfkb-reporter[Luc] is increased irt Tnf (5 hr)
    *** cells: mEFs<Ikk1~null><xIkk1> in BMS
    *** reqs: xIkk1 [omission]
    *** unaffected by: xIkk1(1-737)"delNBD" [substitution]
    *** source: 19666475-Fig-5d
  *** Nfkb-reporter[Luc] is increased irt Tnf (6 hr)
    *** cells: mEFs in BMS
    *** reqs: Ripk1 [KO] no-bkg-control
    *** source: 12479793-Fig-3a
  *** Nfkb-reporter[Luc] is increased irt Tnf (6 hr)
    *** cells: mEFs<Tak1~null><xTak1> in BMS
    *** reqs: xTak1 [omission]
    *** inhibited by: xTak1(K158R) [addition]
    *** source: 20038579-Fig-7c
  *** Nfkb-reporter[Luc] is increased irt Tnf (6 hr)
    *** cells: mEFs<Tak1~null><xTak1> in BMS
    *** unaffected by: xTak1(K34R) [substitution]
    *** unaffected by: xTak1(K52R/K54R) [substitution]
    *** unaffected by: xTak1(K58R) [substitution]
    *** inhibited by: xTak1(K63R) [substitution]
    *** unaffected by: xTak1(K72R) [substitution]
    *** unaffected by: xTak1(K91R) [substitution]
    *** unaffected by: xTak1(K150R) [substitution]
    *** inhibited by: xTak1(K158R) [substitution]
    *** unaffected by: xTak1(K172R) [substitution]
    *** unaffected by: xTak1(K190R) [substitution]
    *** unaffected by: xTak1(K209R) [substitution]
    *** unaffected by: xTak1(K227R) [substitution]
    *** unaffected by: xTak1(K253R) [substitution]
    *** unaffected by: xTak1(K257R) [substitution]
    *** unaffected by: xTak1(K269R) [substitution]
    *** unaffected by: xTak1(K282R) [substitution]
    *** source: 20038579-Fig-4c
  *** Nfkb-reporter[Luc] is increased irt Tnf (8 hr)
    *** cells: HEK293T in BMS
    *** inhibited by: xTnfaip3 [addition]
    *** unaffected by: xTnfaip3(C103A) [addition]
    *** source: 19131965-Fig-5f
  *** Nfkb-reporter[Luc] is increased irt Tnf (8 hr)
    *** cells: mEFs<Tax1bp1~null> in BMS
    *** inhibited by: xTax1bp1 [addition]
    *** partially inhibited by: xTax1bp1(S593A) [addition]
    *** partially inhibited by: xTax1bp1(S666A) [addition]
    *** inhibited by: xTax1bp1(S593A/S666A) [addition]
    *** source: 21765415-Fig-5b
  *** Nfkb-reporter[Luc] is increased irt Tnf (8 hr)
    *** cells: THP1 in BMS
    *** repressed by: Rnf11 [RNAi]
    *** inhibited by: xRnf11 [addition]
    *** source: 19131965-Fig-2a
  *** Nfkb[RE] oligo-binding[EMSA] is increased irt Tnf (1 hr)
    *** cells: 70Z3<Nemo~null><xNemo> in BMS
    *** inhibited by: NBDpeptide [pretreatment]
    *** source: 14651848-Fig-4c
  *** Nfkb[RE] oligo-binding[EMSA] is increased irt Tnf (2 hr)
    *** cells: HEK293 in BMS
    *** does not req: Atm [RNAi]
    *** source: 14651848-Fig-6a
  *** Nfkb[RE] oligo-binding[EMSA] is increased irt Tnf (2 hr)
    *** cells: HEK293 in BMS
    *** does not req: Atr [RNAi]
    *** source: 14651848-Fig-6a
  *** Nfkb[RE] oligo-binding[EMSA] is increased irt Tnf (30 min)
    *** cells: CEM in BMS
    *** partially inhibited by: LMB [pretreatment]
    *** source: 14651848-Fig-7b
  *** Nfkb[RE] oligo-binding[EMSA] is increased irt Tnf (30 min)
    *** cells: hPBTCs in BMS
    *** source: 16497931-Fig-2g
  *** Nfkb[RE] oligo-binding[EMSA] is increased irt Tnf (times)
    *** cells: mEFs in BMS "nuclear-extracts"
    *** times: 0 15+ 30++ 60+ min
    *** partially reqs: Ikk1 [KO]
    *** source: 19666475-Fig-5c
  *** Nfkb[RE] oligo-binding[EMSA] is increased irt Tnf (times)
    *** cells: mEFs<Ikk1~null><xIkk1> in BMS "nuclear-extracts"
    *** times: 0 15++ 30++ 60+ min
    *** partially reqs: xIkk1 [omission]
    *** partially inhibited by: xIkk1(1-737)"delNBD" [substitution]
    *** source: 19666475-Fig-5c
*** Nfkb1--
  *** Nfkb1-gene mRNA[RTPCR] is increased irt Tnf (12 hr)
    *** cells: THP1 in BMS
    *** does not req: Ampka1 [RNAi]
    *** source: 22833096-Fig-S6
  *** Nfkb1{p50}[Ab] snaggedby[WB] rKpna1[GST] is increased irt Tnf (30 min)
    *** cells: A549 in BMS
    *** source: 15677444-Fig-1a
  *** Nfkb1{p50}[Ab] snaggedby[WB] rKpna1[GST] is unchanged irt Tnf (30 min)
    *** cells: A549 in BMS
    *** source: 15677444-Fig-1b
  *** Nfkb1{p50}[Ab] snaggedby[WB] rKpna5[GST] is unchanged irt Tnf (30 min)
    *** cells: A549 in BMS
    *** source: 15677444-Fig-1a
  *** Nfkb1{p50}[Ab] snaggedby[WB] rKpna6[GST] is unchanged irt Tnf (30 min)
    *** cells: A549 in BMS
    *** source: 15677444-Fig-1a
  *** Nfkb1{p50}[Ab] snaggedby[WB] rKpna6[GST] is unchanged irt Tnf (30 min)
    *** cells: A549 in BMS
    *** source: 15677444-Fig-1b
  *** Nfkb1{p50}[Ab] snaggedby[WB] rKpnb1[GST] is unchanged irt Tnf (30 min)
    *** cells: A549 in BMS
    *** source: 15677444-Fig-1b
*** Nfkb2--
  *** Nfkb2-gene mRNA[MicroArray] is increased irt Tnf (4 hr)
    *** cells: L929SA in BMS
    *** unaffected by: SB203580 + PD98059 [addition]
    *** source: 12628924-Fig-8e
  *** Nfkb2-gene mRNA[MicroArray] is increased irt Tnf (4 hr)
    *** cells: mEFs in BMS
    *** does not req: Msk1 and/or Msk2 [DKO]
    *** source: 12628924-Fig-8e
  *** Nfkb2[Ab] cleavage[WB] is unchanged irt Tnf (times)
    *** cells: HEK293<xCd40> in BMS
    *** times: 0 30 300 min
    *** source: 12374738-Fig-1d
  *** Nfkb2{p52}[Ab] copptby[WB] Ikke[Ab] is detectable-but unchanged irt Tnf (24 hr)
    *** cells: HELA in BMS
    *** source: 17003035-Fig-2d
  *** xNfkb2{p52}[Gal4-DBD] Gal4-reporter[Luc] is increased irt Tnf (24 hr)
    *** cells: HEK293 in BMS
    *** enhanced by: xIkke [addition]
    *** unaffected by: xIkke(K38A)"KD" [addition]
    *** unaffected by: xIkk1 [addition]
    *** source: 17003035-Fig-4d
  *** Nfkb2{p100}[Ab] copptby[WB] Ikke[Ab] is increased irt Tnf (24 hr)
    *** cells: HELA in BMS
    *** comment: this could be due to increase in Nfkb2 prot-exp
    *** source: 17003035-Fig-2a
  *** Nfkb2{p100}[Ab] copptby[WB] Rela[Ab] is increased irt Tnf (24 hr)
    *** cells: HELA in BMS
    *** source: 17003035-Fig-5b
  *** Nfkb2{p100}[Ab]IP prot-exp[WB] is increased irt Tnf (24 hr)
    *** cells: HELA in BMS
    *** source: 17003035-Fig-2b
  *** Nfkbiz-gene mRNA[Northern] is unchanged irt Tnf (2 hr)
    *** cells: mLFs in BMS
    *** source: 15241416-Fig-1a
*** Nos2a--
  *** Nos2a-gene mRNA[RTPCR] is increased irt Tnf (times)
    *** cells: mBMMs in BMS
    *** times: 0 30+ 60+ 180++ min
    *** unaffected by: Pias1 [KO]
    *** source: 15657437-Fig-3a
  *** Nos2a-gene mRNA[RTPCR] is increased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0 30 60+ 180++ min
    *** repressed by: Pias4 [KO]
    *** source: 17606919-Fig-3b
  *** Nos2a-gene mRNA[RTPCR] is increased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0 30+ 60++ 180++ min
    *** unaffected by: Pias4 [KO]
    *** source: 17606919-Fig-2a
  *** Nos2a-gene mRNA[RTPCR] is unchanged irt Tnf (times)
    *** cells: mBMDCs in BMS
    *** times: 0 1 2 4 6 hr
    *** comment: unaffected by Ifng pretreatment (4 hr)
    *** source: 17018642-Fig-6
  *** P38s[phosAb] phos(TGY)[phosAb] is unchanged irt Tnf (times)
    *** cells: HACAT in BMLS
    *** times: 0 5 15 30 60 120 min
    *** source: 18675783-Fig-4a
*** Parp1--
  *** Parp1[Ab] cleavage[WB] is increased irt Tnf (6 hr)
    *** cells: HELA in BMS
    *** repressed by: Erc1 [RNAi]
    *** source: 15218148-Fig-3e
  *** Parp1[Ab] cleavage[WB] is increased irt Tnf (16 hr)
    *** cells: JURKAT<Pten~null> in BMS
    *** partially inhibited by: xSyk [addition]
    *** partially repressed by: Syk [RNAi]
    *** source: 15240695-Fig-6c
  *** Parp1[Ab] cleavage[WB] is increased irt Tnf (24 hr)
    *** cells: JURKAT<Pten~null><Ripk1~null><xRipk1> in BMS
    *** inhibited by: xRipk1(K377R)"Ubiq-deficient-mut" [substitution]
    *** source: 16603398-Fig-3b
  *** Parp1[Ab] cleavage[WB] is unchanged irt Tnf (24 hr)
    *** cells: JURKAT<Pten~null> in BMS
    *** repressed by: Ripk1 [KO]
    *** source: 16603398-Fig-3b
  *** Pik3cb-gene mRNA[RTPCR] is increased irt Tnf (12 hr)
    *** cells: THP1 in BMS
    *** reqs: Ampka1 [RNAi]
    *** source: 22833096-Fig-7c
*** Pin1--
  *** Pin1[Ab] copptby[WB] Rela[Ab] is increased irt Tnf (tnr)
    *** cells: HEK293T in BMS
    *** comment: lysates were immunodepleted of Ikba first
    *** source: 14690596-Fig-3b
  *** Pkca[phosAb] phos(S657)[phosAb] is detectable-but unchanged irt Tnf (30 min)
    *** cells: mEFs in BMS
    *** source: 21464307-Fig-S2a
*** Pkci--
  *** Pkci[Ab] copptby[WB] Dusp1[Ab] is increased irt Tnf (times)
    *** cells: HEK293 in BMS
    *** times: 0 1 5+ min
    *** source: 10022904-Fig-3c
*** Pkcz--
  *** Pkcz[Ab]IP IVKA(snr)[32P-ATP] is increased irt Tnf (10 min)
    *** cells: EJ in BMLS
    *** source: 9020886-Fig-3
  *** Pkcz[Ab]IP IVKA(snr)[32P-ATP] is increased irt Tnf (10 min)
    *** cells: TE671 in BMLS
    *** source: 9020886-Fig-3
  *** xPkcz[tAb]IP phos[32Pi] is increased irt Tnf (10 min)
    *** cells: BOSC23 in BMLS
    *** source: 9020886-Fig-4
  *** Ppm1a-gene mRNA[RTPCR] is increased irt Tnf (16 hr)
    *** cells: L6 in BMLS  "myotubes"
    *** times: 0 2+ 8++ 16+++ hr
    *** source: 17141630(D)
*** Ptgs2--
  *** Ptgs2-gene mRNA[Northern] is increased irt Tnf (16 hr)
    *** cells: mEFs in BMS
    *** does not req: Tab2 [KO]
    *** source: 12556483-Fig-3c
  *** Ptgs2-gene mRNA[RTPCR] is increased irt Tnf (times)
    *** cells: HELA in BMS
    *** times: 0 30+ 60+ 120 min
    *** reqs: Erc1 [RNAi]
    *** source: 15218148-Fig-3b
*** Rel--
  *** Rel-gene mRNA[RTPCR] is increased irt Tnf (12 hr)
    *** cells: THP1 in BMS
    *** does not req: Ampka1 [RNAi]
    *** source: 22833096-Fig-S6
  *** Rel[Ab] oligo-binding[EMSA] is unchanged irt Tnf (30 min)
    *** cells: mEFs in BMS
    *** source: 9390694-Fig-6b
*** Rela--
  *** Rela[Ab] copptby[WB] Ikba[Ab] is decreased irt Tnf (tnr)
    *** cells: HEK293T in BMS
    *** source: 14690596-Fig-3b
  *** Rela[Ab] copptby[WB] Ikke[Ab] is increased irt Tnf (24 hr)
    *** cells: HELA in BMS
    *** source: 17003035-Fig-5c
  *** Rela[Ab] copptby[WB] Msk1[Ab] is increased irt Tnf (15 min)
    *** cells: L929SA in BMS
    *** inhibited by: H89 [addition]
    *** source: 12628924-Fig-6b
  *** Rela[Ab] copptby[WB] Nfkb2[Ab] is increased irt Tnf (24 hr)
    *** cells: HELA in BMS
    *** source: 17003035-Fig-5b
  *** Rela[Ab] copptby[WB] Pkcz[Ab] is increased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0 5+ 10+ 20+ min
    *** inhibited by: Lactacystin [addition]
    *** source: 11684013-Fig-4c
  *** Rela[Ab] snaggedby[WB] rKpna1[GST] is increased irt Tnf (30 min)
    *** cells: A549 in BMS
    *** source: 15677444-Fig-1a
  *** Rela[Ab] snaggedby[WB] rKpna1[GST] is unchanged irt Tnf (30 min)
    *** cells: A549 in BMS
    *** source: 15677444-Fig-1b
  *** Rela[Ab] snaggedby[WB] rKpna3[GST] is increased irt Tnf (30 min)
    *** cells: A549 in BMS
    *** source: 15677444-Fig-1a
  *** Rela[Ab] snaggedby[WB] rKpna3[GST] is increased irt Tnf (30 min)
    *** cells: A549 in BMS
    *** source: 15677444-Fig-1b
  *** Rela[Ab] snaggedby[WB] rKpna3[GST] is increased irt Tnf (30 min)
    *** cells: A549 in BMS
    *** unaffected by: rKpna3(mnr)"ARM3" [substitution]
    *** inhibited by: rKpna3(mnr)"ARM7+8" [substitution]
    *** source: 15677444-Fig-7c
  *** Rela[Ab] snaggedby[WB] rKpna3[GST] is increased irt Tnf (times)
    *** cells: A549 in BMS
    *** times: 0 1 2 4 8+ 15++ 30+++ 60+++ 120++ min
    *** source: 15677444-Fig-3b
  *** Rela[Ab] snaggedby[WB] rKpna4[GST] is increased irt Tnf (30 min)
    *** cells: A549 in BMS
    *** source: 15677444-Fig-1b
  *** Rela[Ab] snaggedby[WB] rKpna5[GST] is unchanged irt Tnf (30 min)
    *** cells: A549 in BMS
    *** source: 15677444-Fig-1a
  *** Rela[Ab] snaggedby[WB] rKpna6[GST] is unchanged irt Tnf (30 min)
    *** cells: A549 in BMS
    *** source: 15677444-Fig-1a
  *** Rela[Ab] snaggedby[WB] rKpna6[GST] is unchanged irt Tnf (30 min)
    *** cells: A549 in BMS
    *** source: 15677444-Fig-1b
  *** Rela[Ab] snaggedby[WB] rKpnb1[GST] is unchanged irt Tnf (30 min)
    *** cells: A549 in BMS
    *** source: 15677444-Fig-1a
  *** xRela[Ab] snaggedby[WB] rPin1[GST] is increased irt Tnf (tnr)
    *** cells: HELA in BMS
    *** source: 14690596-Fig-3c
  *** Rela[Ab]IP phos[32Pi] is increased irt Tnf (5 min)
    *** cells: HELA in BMS
    *** unaffected by: ALLN [addition]
    *** source: 10521409-Fig-1d
  *** Rela[Ab]IP phos[32Pi] is increased irt Tnf (10 min)
    *** cells: HELA in BMS
    *** inhibited by: PD144795 [addition]
    *** source: 10938077-Fig-3c
  *** Rela[Ab]IP phos[32Pi] is increased irt Tnf (10 min)
    *** cells: HELA in BMS
    *** source: 9792644-Fig-1
  *** Rela[Ab]IP phos[32Pi] is increased irt Tnf (15 min)
    *** cells: L929SA in BMS
    *** inhibited by: H89 [addition]
    *** source: 12628924-Fig-2c
  *** Rela[Ab]IP phos[32Pi] is increased irt Tnf (times)
    *** cells: HELA in BMS
    *** times: 0 2 5+ 10+ 20+ min
    *** source: 10521409-Fig-1b
  *** Rela[phosAb] phos(S311)[phosAb] is increased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0 10+ 30++ min
    *** reqs: Pkcz [KO]
    *** source: 12881425-Fig-2a
  *** Rela[phosAb] phos(S468)[phosAb] is detectable-but unchanged irt Tnf (15 min)
    *** cells: SKW64 in BMS
    *** source: 16046471-Fig-3b
  *** Rela[phosAb] phos(S468)[phosAb] is increased irt Tnf (15 min)
    *** cells: HELA in BMS
    *** inhibited by: PS1145 [pretreatment]
    *** unaffected by: SB203580 [pretreatment]
    *** unaffected by: PD98059 [pretreatment]
    *** unaffected by: LY294002 [pretreatment]
    *** unaffected by: SP600125 [pretreatment]
    *** unaffected by: GSK3inhibitorI [pretreatment]
    *** source: 16046471-Fig-4d
  *** Rela[phosAb] phos(S468)[phosAb] is increased irt Tnf (15 min)
    *** cells: HELA in BMS
    *** inhibited by: xIkk2(mnr)"DN" [addition]
    *** source: 16046471-Fig-4a
  *** Rela[phosAb] phos(S468)[phosAb] is increased irt Tnf (15 min)
    *** cells: HELA in BMS
    *** source: 16046471-Fig-3b
  *** Rela[phosAb] phos(S468)[phosAb] is increased irt Tnf (15 min)
    *** cells: HELA in BMS
    *** unaffected by: xIkba(mnr)"SuperRepressor" [addition]
    *** source: 16046471-Fig-4a
  *** Rela[phosAb] phos(S468)[phosAb] is increased irt Tnf (15 min)
    *** cells: HELA in BMS
    *** unaffected by: xIkk1(mnr)"DN" [addition]
    *** source: 16046471-Fig-4a
  *** Rela[phosAb] phos(S468)[phosAb] is increased irt Tnf (15 min)
    *** cells: HEP3B in BMS
    *** source: 16046471-Fig-3b
  *** Rela[phosAb] phos(S468)[phosAb] is increased irt Tnf (15 min)
    *** cells: hHepaticStellateCells in BMS
    *** source: 16046471-Fig-3b
  *** Rela[phosAb] phos(S468)[phosAb] is increased irt Tnf (15 min)
    *** cells: hPBMCs in BMS
    *** source: 16046471-Fig-3b
  *** Rela[phosAb] phos(S468)[phosAb] is increased irt Tnf (15 min)
    *** cells: JURKAT<Pten~null> in BMS
    *** source: 16046471-Fig-3b
  *** Rela[phosAb] phos(S468)[phosAb] is increased irt Tnf (15 min)
    *** cells: MCF7 in BMS
    *** source: 16046471-Fig-3b
  *** xRela[phosAb] phos(S468)[phosAb] is increased irt Tnf (15 min)
    *** cells: mEFs<Rela~null><xRela> in BMS
    *** inhibited by: xRela(S468A) [substitution]
    *** source: 16046471-Fig-5a
  *** Rela[phosAb] phos(S468)[phosAb] is increased irt Tnf (15 min)
    *** cells: U251 in BMS
    *** source: 16046471-Fig-3b
  *** Rela[phosAb] phos(S468)[phosAb] is increased irt Tnf (times)
    *** cells: HELA in BMS
    *** times: 0 7++ 15+ 30 60 120 min
    *** enhanced by: CalyculinA [pretreatment]
    *** source: 16046471-Fig-3a
  *** Rela[phosAb] phos(S468)[phosAb] is unchanged irt Tnf (15 min)
    *** cells: hPBMCs in BMS
    *** source: 16046471-Fig-3b
  *** Rela[phosAb] phos(S529)[phosAb] is increased irt Tnf (times)
    *** cells: HELA in BMS
    *** times: 0 5+ 10+ 30 min
    *** inhibited by: MG132 [addition]
    *** source: 10938077-Fig-4
  *** Rela[phosAb] phos(sitenr)[phosAb] is increased irt Tnf (times)
    *** cells: HELA in BMS
    *** times: 0 5+ 10+ 15++ 30++ min
    *** bkg repressed by: Usp21 [RNAi]
    *** source: 19910467-Fig-4b
  *** xRela[tAb]IP phos(S311)[phosAb] is increased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0 10+ 30++ min
    *** inhibited by: xRela(S311A) [substitution]
    *** source: 12881425-Fig-2a
  *** xRela[tAb]IP phos[32Pi] is increased irt Tnf (10 min)
    *** cells: mEFs<Rela~null> in BMS
    *** inhibited by: xRela(S529A) [substitution]
    *** unaffected by: xRela(S276A) [substitution]
    *** source: 9792644-Fig-5
  *** xRela[tAb]IP phos[32Pi] is increased irt Tnf (tnr)
    *** cells: HEK293T in BMS
    *** inhibited by: xRela(T254A) [substitution]
    *** source: 14690596-Fig-3h
*** Ripk1--
  *** Ripk1[Ab] cleavage[WB] is increased irt Tnf (times)
    *** cells: HT1080 in BMS
    *** times: 0 5 30 60 120++ 240++ 480+ min
    *** comment: prolonged by xIkba(mnr)"degradation-deficient-mut" [addition]
    *** source: 12887920(D)
  *** Ripk1[Ab] copptby[WB] Casp8[Ab] is increased irt Tnf (6 hr)
    *** cells: JURKAT<Pten~null> in BMS
    *** reqs: Fadd [KO]
    *** source: 12887920(D)
  *** Ripk1[Ab] copptby[WB] Fadd[Ab] is increased irt Tnf (times)
    *** cells: HT1080<xIkba(mnr)"DN"> in BMS
    *** times: 0 5 30 60+ 90++ 180+ min
    *** source: 16940186-Fig-4c
  *** Ripk1[Ab] phos[WBMS-PPase] is increased irt Tnf (10 min)
    *** cells: mEFs in BMS
    *** source: 15175328-Fig-1b
  *** Ripk1[Ab] phos[WBMS] is increased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0 5+ 10+ min
    *** source: 16115877-Fig-8a,8b
  *** Ripk1[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs<Nemo~null> in BMS
    *** times: 0++ 5++ 60+ 120 min
    *** comment: Ripk1 is upshifted at 5 min
    *** source: 16547522-Fig-5c
  *** Ripk1[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs<Nemo~null><xNemo(L320P)> in BMS
    *** times: 0++ 5++ 30++ 60+ 120 min
    *** comment: Ripk1 is upshifted at 5 min
    *** inhibited by: MG132 [addition]
    *** comment: Ripk1 is upshifted at 5-120 min itpo MG132
    *** source: 16547522-Fig-5d
  *** Ripk1[Ab] prot-exp[WB] is unchanged irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 5+ 60+ 120+ min
    *** comment: Ripk1 is upshifted at 5 min
    *** source: 16547522-Fig-5c
  *** Ripk1[Ab] prot-exp[WB] is unchanged irt Tnf (times)
    *** cells: mEFs<Nemo~null><xNemo> in BMS
    *** times: 0+ 5+ 30+ 60+ 120+ min
    *** comment: Ripk1 is upshifted at 5 min
    *** unaffected by: MG132 [addition]
    *** comment: Ripk1 is upshifted at 5-120 min itpo MG132
    *** source: 16547522-Fig-5d
*** Rnf11--
  *** Rnf11[Ab] prot-exp[WB] is unchanged irt Tnf (8 hr)
    *** cells: THP1 in BMS
    *** source: 19131965-Fig-2a
*** RoRc-- RoRc-gene--
  *** RoRc-gene mRNA[RTPCR] is unchanged irt Tnf (3 days)
    *** cells: hNaiveCD4TCs in BMS
    *** source: 18454151-Fig-2b
*** Rsks--
  *** Rsks[phosAb] phos(sitenr)[phosAb] is increased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0 15+ 30 min
    *** does not req: Ikk1 [KO]
    *** does not req: Ikk2 [KO]
    *** comment: decrease in phos at 30 min is not seen in Ikk-null cells
    *** source: 11733537-Fig-2
  *** Rsks[phosAb] phos(T359/S363)[phosAb] is increased irt Tnf (5 min)
    *** cells: MEWO in BMLS
    *** source: 19274086-Fig-2a
  *** Rsks[phosAb] phos(T359/S363)[phosAb] is unchanged irt Tnf (5 min)
    *** cells: 3731T in BMLS
    *** source: 19274086-Fig-2a
  *** Rsks[phosAb] phos(T359/S363)[phosAb] is unchanged irt Tnf (5 min)
    *** cells: B16F1 in BMLS
    *** source: 19274086-Fig-2a
*** S1p--
  *** S1p[Ab] secretion[ELISA] is increased irt Tnf (30 min)
    *** cells: HEK293<xSphk1> in BMS
    *** inhibited by: xSphk1(S225A) [substitution]
    *** source: 14532121(D)
  *** Sgk1-gene mRNA[RTPCR] is increased irt Tnf (12 hr)
    *** cells: THP1 in BMS
    *** reqs: Ampka1 [RNAi]
    *** source: 22833096-Fig-7c
*** Smad6--
  *** Smad6-gene mRNA[RTPCR] is unchanged irt Tnf (2 hr)
    *** cells: mPECs in BMLS
    *** source: 17384642-Fig-4g
*** Smad7--
  *** Smad7-gene mRNA[RTPCR] is unchanged irt Tnf (2 hr)
    *** cells: mPECs in BMLS
    *** source: 17384642-Fig-4f
  *** Smad7-gene mRNA[RTPCR] is unchanged irt Tnf (6 hr)
    *** cells: CMT93 in BMS
    *** source: 17384642-Fig-S3a
  *** Smad7-gene mRNA[RTPCR] is unchanged irt Tnf (6 hr)
    *** cells: CMT93 in BMS
    *** source: 17384642-Fig-S3b
  *** Smad7-gene mRNA[RTPCR] is unchanged irt Tnf (6 hr)
    *** cells: mBMMs in BMS
    *** source: 17384642-Fig-S3a
  *** xSmad7[tAb] copptby[WB] Tab2[Ab] is unchanged irt Tnf (times)
    *** cells: MCF7 in BMS
    *** times: 0+ 5+ 15+ 30+ min
    *** source: 17384642-Fig-6d
*** Sp1--
  *** Sp1[RE] oligo-binding[EMSA] is unchanged irt Tnf (15 min)
    *** cells: MCF7 in BMS
    *** comment: binding is unaffected by addition of rPias1 to lysates
    *** source: 15657437-Fig-7c
*** Sphk1--
  *** Sphk1[Ab]IP IVLKA(Sphingosine)[TLC] is increased irt Tnf (times)
    *** cells: HEK293 in BMS
    *** times: 0 7+ 15++ 30++ min
    *** source: 14532121(D)
  *** Sphk1[Ab]IP phos(S225)[phosAb] is increased irt Tnf (times)
    *** cells: HEK293 in BMS
    *** times: 0 7++ 15+ 30+ min
    *** inhibited by: Geldanamycin [addition]
    *** source: 14532121(D)
  *** xSphk1[phosAb] phos(S225)[phosAb] is increased irt Tnf (times)
    *** cells: HEK293<xSphk1> in BMS
    *** times: 0 7+ 15+ 30+ min
    *** inhibited by: PD98059 [addition]
    *** inhibited by: U0126 [addition]
    *** source: 14532121(D)
  *** xSphk1[tAb]IP IVLKA(Sphingosine)[TLC] is increased irt Tnf (times)
    *** cells: HEK293<xSphk1> in BMS
    *** times: 0 7+ 15++ 30++ min
    *** inhibited by: xSphk1(S225A) [substitution]
    *** source: 14532121(D)
  *** xSphk1[tAb]IP phos[32Pi] is increased irt Tnf (times)
    *** cells: HEK293<xSphk1> in BMS
    *** times: 0 5+ 10++ 30++ min
    *** source: 14532121(D)
*** Sqstm1--
  *** Sqstm1[Ab] copptby[WB] Ripk1[Ab] is increased irt Tnf (times)
    *** cells: HELA in BMS
    *** times: 0 2++ 5++ 10+ 20 min
    *** source: 10356400-Fig-3d
  *** Sqstm1[Ab] copptby[WB] TnfR1[Ab] is increased irt Tnf (times)
    *** cells: HELA in BMS
    *** times: 0 2++ 5++ 10+ 20 min
    *** source: 10356400-Fig-8
  *** xSqstm1[tAb] copptby[WB] Ripk1[Ab] is increased irt Tnf (times)
    *** cells: HEK293 in BMS
    *** times: 0 2++ 5+ 10+ 20 min
    *** source: 10356400-Fig-3d
*** Stat1--
  *** Stat1[Ab] locatedin(nucleus)[IHC] is unchanged irt Tnf (times)
    *** cells: A431 in BMS
    *** times: 0 60 min
    *** source: 10848577-Fig-3c
*** Stat3--
  *** xStat3[phosAb] phos(S727)[phosAb] is increased irt Tnf (30 min)
    *** cells: NIH3T3<xStat3> in BMS
    *** source: 10521505-Fig-1a
  *** xStat3[phosAb] phos(S727)[phosAb] is increased irt Tnf (45 min)
    *** cells: COS1<xStat3> in BMS
    *** source: 10521505-Fig-1a
  *** xStat3[phosAb] phos(Y705)[phosAb] is unchanged irt Tnf (45 min)
    *** cells: COS1<xStat3> in BMS
    *** source: 10521505-Fig-1a
*** Stat6--
  *** Stat6[Ab] oligo-binding[EMSA] is unchanged irt Tnf (30 min)
    *** cells: hFibros in BMS
    *** source: 11544308-Fig-5
  *** Stat6[Ab]IP Yphos[pYAb] is unchanged irt Tnf (40 min)
    *** cells: HACAT in BMS
    *** source: 12776189-Fig-2a
  *** Stat6RE-reporter[Luc] is unchanged irt Tnf (40 min)
    *** cells: HACAT in BMS
    *** source: 12776189-Fig-2b
*** Syk--
  *** Syk[Ab] copptby[WB] TnfR2[Ab] is increased irt Tnf (times)
    *** cells: JURKAT<Pten~null> in BMS
    *** times: 0 15+ 30++ 60+ 120 sec
    *** source: 15240695-Fig-8b
  *** xSyk[Ab] copptby[WB] TnfR2[Ab] is increased irt Tnf (tnr)
    *** cells: JURKAT<Pten~null> in BMS
    *** source: 15240695-Fig-8c
*** Tab1--
*** Tab2--
*** Tak1--
*** Tank--
  *** Tank-gene mRNA[RTPCR] is unchanged irt Tnf (tnr)
    *** cells: HELA in BMS
    *** source: 16336209-Fig-8
*** Tax1bp1--
  *** Tax1bp1[Ab] prot-exp[WB] is increased irt Tnf (times)
    *** cells: mBMMs in BMS
    *** times: 0 15+ 60+ min
    *** source: 21765415-Fig-2k
  *** Tax1bp1[Ab]IP prot-exp[WB] is increased irt Tnf (15 min)
    *** cells: mEFs<Ikk1~null><xIkk1> in BMS
    *** unaffected by: xIkk1(K44M)"KD" [substitution]
    *** source: 21765415-Fig-1g
*** Tnf--
  *** Tnf[125I] internalization[Surface-strip] is increased irt Tnf (60 min)
    *** cells: U937 in BMS
    *** inhibited by: Monodansylcadaverine [addition]
    *** source: 10187805-Fig-1a
  *** Tnf[biotin] internalization[IHC] is increased irt Tnf (times)
    *** cells: U937 in BMS
    *** times: 0 30+ 60++ min
    *** inhibited by: Monodansylcadaverine [addition]
    *** source: 10187805-Fig-1a
*** Tnfaip3--
*** TnfR1--
  *** TnfR1[Ab] colocwith[IHC] Cav1[Ab] is detectable
    *** cells: EAHY926 in BMS
    *** inhibited by: Methyl-beta-cyclodextrin [addition]
    *** source: 15793306-Fig-1c
  *** TnfR1[Ab] colocwith[IHC] Cltc[Ab] is detectable
    *** cells: EAHY926 in BMLS
    *** unaffected by: Tnf (30,60 min) [stim]
    *** source: 15793306-Fig-6
  *** TnfR1[Ab] colocwith[IHC] Cltc[Ab] is increased irt Tnf (60 min)
    *** cells: EAHY926 in BMLS
    *** source: 15793306-Fig-7a
  *** TnfR1[Ab] colocwith[IHC] Rab5s[Ab] is increased irt Tnf (60 min)
    *** cells: EAHY926 in BMLS
    *** source: 15793306-Fig-7a
  *** TnfR1[Ab] copptby[WB] Cav1[Ab] is detectable
    *** cells: EAHY926 in BMLS
    *** inhibited by: Methyl-beta-cyclodextrin [addition]
    *** source: 15793306-Fig-5
  *** TnfR1[Ab] surface-exp[FACS] is decreased irt Tnf (times)
    *** cells: EAHY926 in BMLS
    *** times: 0+++ 5++ 15+ 30+ 60+ min
    *** inhibited by: Methyl-beta-cyclodextrin [addition]
    *** source: 15793306-Fig-4d
  *** TnfR1[Ab]IP ubiq[tUbAb] is increased irt Tnf (times)
    *** cells: HT1080<xUbiq> in BMS
    *** times: 0 2+ 10++ min
    *** comment: TnfR1-Ubiq was located in the Triton-Insoluble fraction
    *** source: 12753742(D)
*** TnfR2--
  *** TnfR2[Ab] copptby[WB] Syk[Ab] is increased irt Tnf (times)
    *** cells: JURKAT<Pten~null> in BMS
    *** times: 0 15+ 30++ 60+ 120 sec
    *** source: 15240695-Fig-8a
*** Tnik
  *** Tnik[Ab] prot-exp[WB] is increased irt Tnf (24 hr)
    *** cells: SW480 in BMS
    *** source: 21710659-Fig-3a
*** Tpl2--
  *** Tpl2[Ab] copptby[WB] Nfkb1[Ab] is decreased irt Tnf (10 min)
    *** cells: HELA in BMS
    *** comment: only the long form of TPl2 is decreased irt Tnf
    *** inhibited by: Piceatannol [addition]
    *** source: 16291755-Fig-5a
  *** Tpl2[Ab] copptby[WB] Nfkb1[Ab] is decreased irt Tnf (10 min)
    *** cells: mBMMs in BMS
    *** comment: only the long form of TPl2 is decreased irt Tnf
    *** inhibited by: Piceatannol [addition]
    *** source: 16291755-Fig-5a
*** Tradd--
  *** Tradd[Ab] cleavage[WB] is increased irt Tnf (times)
    *** cells: HT1080 in BMS
    *** times: 0 5 30 60 120 240+ 480+ min
    *** enhanced by: xIkba(mnr)"degradation-mut" [addition]
    *** source: 12887920(D)
  *** Tradd[Ab] copptby[WB] Casp8[Ab] is increased irt Tnf (times)
    *** cells: HT1080 in BMS
    *** times: 0 5 30 60++ 120++ 240++ 480+ min
    *** comment: prolonged by xIkba(mnr)"degradation-deficient-mut" [addition]
    *** source: 12887920(D)
*** Traf1--
  *** Traf1[Ab] copptby[WB] Casp8[Ab] is increased irt Tnf (times)
    *** cells: HT1080 in BMS
    *** times: 0 5 30 60+ 120+ 240++ 480++++ min
    *** inhibited by: xIkba(mnr)"degradation-deficient-mut" [addition]
    *** source: 12887920(D)
*** Traf2--
  *** Traf2[Ab] copptby[WB] Casp8[Ab] is increased irt Tnf (times)
    *** cells: HT1080 in BMS
    *** times: 0 5 30 60++ 120++ 240++ 480+ min
    *** comment: prolonged by xIkba(mnr)"degradation-deficient-mut" [addition]
    *** source: 12887920(D)
  *** Traf2[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: JURKAT<Pten~null><xTnfR2> in BMS
    *** times: 0+++ 30+++ 60+++ 120++ 240+ min
    *** reqs: xTnfR2 [omission]
    *** inhibited by: Lactacystin [addition]
    *** source: 11907583-Fig-1a
  *** Traf2[Ab] prot-exp[WB] is unchanged irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 10+ 20+ 30+ 60+ 90+ 120+ 180+ min
    *** does not req: Tnfaip3 [KO]
    *** source: 11009421-Fig-2c
  *** xTraf2[tAb] prot-exp[WB] is decreased irt Tnf (4 hr)
    *** cells: JURKAT<Pten~null><xTnfR2> in BMS
    *** inhibited by: xCiap1(mnr)"E3-activity-mut" [substitution]
    *** source: 11907583-Fig-1a
*** Traf6--
  *** Traf6[Ab] copptby[WB] Tab2[Ab] is unchanged irt Tnf (times)
    *** cells: HEK293<xIL1R1> in BMS
    *** times: 0 3 15 min
    *** source: 14633987-Fig-6b
  *** Traf6[Ab] copptby[WB] Tab3[Ab] is unchanged irt Tnf (times)
    *** cells: HEK293<xIL1R1> in BMS
    *** times: 0 3 15 min
    *** source: 14633987-Fig-6b
  *** Traf6[Ab] copptby[WB] TnfR1[Ab] is unchanged irt Tnf (10 min)
    *** cells: HEK293 in BMS
    *** source: 16115877-Fig-7b
*** Tsc1--
  *** Tsc1[Ab]IP ubiq[UbAb] is increased irt Tnf (30 min)
    *** cells: MCF7 in BMS "pretreated with MG132"
    *** source: 17693255-Fig-S10a
*** Tsc2--
  *** Tsc2[Ab] infraction(membrane)[WB] is unchanged irt Tnf (30 min)
    *** cells: MCF7 in BMLS
    *** comment: author says that there is a decrease
    *** source: 17693255-Fig-5f
  *** Tsc2[Ab]IP ubiq[UbAb] is increased irt Tnf (30 min)
    *** cells: MCF7 in BMS "pretreated with MG132"
    *** source: 17693255-Fig-S10a
*** Ubc13--
  *** Ubc13[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mBMMs in BMS
    *** times: 0++ 2++ 4+ 6 hr
    *** repressed by: Tnfaip3 [RNAi]
    *** source: 20185725-Fig-3d
  *** Ubc13[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 2+ 4+ 6 hr
    *** does not req: Itch [KO]
    *** source: 20185725-Fig-S5c
  *** Ubc13[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 2+ 4+ 6 hr
    *** does not req: Rnf11 [RNAi]
    *** source: 20185725-Fig-S5a
  *** Ubc13[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0+ 2+ 4+ 6 hr
    *** reversed by: MG132 [pretreatment]
    *** source: 20185725-Fig-3e
  *** Ubc13[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0++ 2++ 4+ 6 hr
    *** repressed by: Tax1bp1 [KO]
    *** source: 20185725-Fig-S4d
  *** Ubc13[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0++ 2++ 4+ 6 hr
    *** repressed by: Tnfaip3 [KO]
    *** source: 20185725-Fig-S4b
  *** Ubc13[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs<Tnfaip3~null><xTnfaip3> in BMS
    *** times: 0+ 1+ 2+ 4+ 6 hr
    *** comment: reversed by xTnfaip3(C103A) [subsitution]
    *** comment: reversed by xTnfaip3(C624A/C627A) [subsitution]
    *** source: 20185725-Fig-S8b
  *** Ubc13[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs<Tnfaip3~null><xTnfaip3> in BMS
    *** times: 0+ 2+ 4+ 6 hr
    *** unaffected by: xTnfaip3(1-699) [substitution]
    *** unaffected by: xTnfaip3(1-640) [substitution]
    *** reversed by: xTnfaip3(1-468) [substitution]
    *** reversed by: xTnfaip3(1-367) [substitution]
    *** reversed by: xTnfaip3(1-590) [substitution]
    *** source: 20185725-Fig-4b
  *** Ubc13[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs<Tnfaip3~null><xTnfaip3> in BMS
    *** times: 0+ 2+ 4+ 6 hr
    *** unaffected by: xTnfaip3(1-699) [substitution]
    *** unaffected by: xTnfaip3(1-640) [substitution]
    *** reversed by: xTnfaip3(1-468) [substitution]
    *** reversed by: xTnfaip3(1-367) [substitution]
    *** reversed by: xTnfaip3(1-590) [substitution]
    *** source: 20185725-Fig-S6
  *** Ubc13[Ab]IP ubiq[tUbAb] is increased irt Tnf (4 hr)
    *** cells: mEFs<xUbiq> in BMS
    *** inhibited by: xUbiq(K63only) [substitution]
    *** unaffected by: xUbiq(K48only) [substitution]
    *** source: 20185725-Fig-3b
  *** Ubc13[Ab]IP ubiq[UbAb] is increased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0 3+ 4++ hr
    *** reqs: Tax1bp1 [KO]
    *** source: 20185725-Fig-S3a
  *** Ubc13[Ab]IP ubiq[UbAb] is increased irt Tnf (times)
    *** cells: mEFs in BMS
    *** times: 0 3+ 4++ hr
    *** reqs: Tnfaip3 [KO]
    *** source: 20185725-Fig-S3a
*** Ube2d3--
  *** Ube2d3[Ab] prot-exp[WB] is decreased irt Tnf (times)
    *** cells: mEFs<Tnfaip3~null><xTnfaip3> in BMS
    *** times: 0++ 2++ 4+ 6 hr
    *** unaffected by: xTnfaip3(1-699) [substitution]
    *** unaffected by: xTnfaip3(1-640) [substitution]
    *** reversed by: xTnfaip3(1-468) [substitution]
    *** reversed by: xTnfaip3(1-367) [substitution]
    *** reversed by: xTnfaip3(1-590) [substitution]
    *** source: 20185725-Fig-S6
  *** Ube2d3[Ab] prot-exp[WB] is unchanged irt Tnf (times)
    *** cells: mBMMs in BMS
    *** times: 0+ 2++ 4+ 6+ hr
    *** unaffected by: Tnfaip3 [RNAi]
    *** source: 20185725-Fig-3d
*** Usp21--
  *** Usp21[Ab] copptby[WB] Ripk1[Ab] is unchanged irt Tnf (times)
    *** cells: HELA in BMS
    *** times: 0+ 2+ 5+ 15+ 30+ min
    *** source: 19910467-Fig-2e
  *** Usp21[Ab] copptby[WB] Ripk1[Ab] is unchanged irt Tnf (times)
    *** cells: HELA in BMS
    *** times: 0+ 15+ 30+ 60+ 90+ 120+ min
    *** source: 19910467-Fig-S1d
*** Vcam1--
  *** Vcam1[Ab] surface-exp[ELISA] is increased irt Tnf (8 hr)
    *** cells: hUVECs in BMS
    *** inhibited by: Ebselen [pretreatment]
    *** source: 14720501-Fig-7a
  *** Vegf[Ab] secretion[WB] is increased irt Tnf (tnr)
    *** cells: MCF7<xTsc1> in BMS
    *** inhibited by: xTsc1(S487A/S511A) [substitution]
    *** source: 17693255-Fig-S11e
*** Zap70--
  *** Zap70[Ab]IP Yphos[pYAb] is unchanged irt Tnf (times)
    *** cells: JURKAT<Pten~null> in BMS
    *** times: 0 5 15 30 60 120 sec
    *** source: 15240695-Fig-1e
*** TgfbR2--
  *** TgfbR2-gene promo-reporter[Luc] is unchanged irt Tnf (24 hr)
    *** cells: hFibros in BMLS
    *** source: 17107667-Fig-1b
  *** TgfbR2[Ab] prot-exp[WB] is decreased irt Tnf (24 hr)
    *** cells: hFibros in BMLS
    *** source: 17107667-Fig-1a
*** CcL7--
  *** CcL7[Ab] secretion[ELISA] is increased irt Tnf (tnr)
    *** cells: HEK293 in BMS
    *** unaffected by: xSocs1 [addition]
    *** unaffected by: xSocs2 [addition]
    *** unaffected by: xSocs3 [addition]
    *** source: 15589317-Fig-1
  *** CcL7[Ab] secretion[ELISA] is increased irt Tnf (tnr)
    *** cells: HEK293 in BMS
    *** unaffected by: xSocs1 [addition]
    *** unaffected by: xSocs1(F58A) [addition]
    *** unaffected by: xSocs2 [addition]
    *** unaffected by: xSocs3 [addition]
    *** unaffected by: xSocs3(F25A) [addition]
    *** source: 15589317-Fig-7
