=====================================
Proteins required for mRNA expression
=====================================

not Irak1--

  *** IL1b-gene mRNA[RTPCR] is increased irt IL1b (18 hr)
    *** cells: hUVECs in BMS
    *** does not req: Irak1 [RNAi]
    *** source: 19181383-Fig-3b

Irak4--

  *** IL1b-gene mRNA[RTPCR] is increased irt IL1b (18 hr)
    *** cells: hUVECs in BMS
    *** reqs: Irak1 and/or Irak4 [RNAi]
    *** source: 19181383-Fig-3b
  *** IL1b-gene mRNA[RTPCR] is increased irt IL1b (18 hr)
    *** cells: hUVECs in BMS
    *** reqs: Irak4 [RNAi]
    *** comment: response can be rescued with either xIrak4 or xIrak4(K213A/K214A)"KD"
    *** comment: response is not rescued with xIrak4(1-185)
    *** source: 19181383-Fig-4b
  *** IL1b-gene mRNA[RTPCR] is increased irt IL1b (18 hr)
    *** cells: hUVECs in BMS
    *** reqs: Irak4 [RNAi]
    *** source: 19181383-Fig-3a

