=============================================
Use of Trka is based on similarity with EgfR
=============================================
*** Abl1--
  *** Abl1[Ab] copptby[WB] Crks[Ab] is detectable-but unchanged irt Ngf (times)
    *** cells: PC12<xTrka> in BMS
    *** times: 0+ 1+ 2+ 5+ 60+ 180+ min
    *** source: 15167895-Fig-5c
  *** xAbl1[Ab] copptby[WB] xTrka[Ab] is detectable
    *** cells: HEK293T<xAbl1><xTrka> in BMS
    *** source: 10679771-Fig-1
  *** xAbl1[Ab] copptby[WB] xTrka[Ab] is detectable
    *** cells: HEK293T<xAbl1><xTrka> in BMS
    *** unaffected by: xTrka(K538A) [substitution]
    *** source: 10679771-Fig-2
  *** Abl1[Ab] copptby[WB] xTrka[Ab] is detectable
    *** cells: PC12<xTrka> in BMS
    *** source: 10679771-Fig-5
*** Akt1--
*** Araf--
*** Arms--
*** Atf2--
*** Bcar1--
  *** Bcar1[Ab] copptby[WB] Crk[Ab] is increased irt Ngf (times)
    *** cells: PC12 in BMLS
    *** times: 0+ 2+ 5+++ 15+++ 30+++ 60+++ min
    *** source: 11278445-Fig-5c
*** Braf--
  *** Braf[Ab] copptby[WB] Raf1[Ab] is increased irt Ngf (times)
    *** cells: PC12 in BMLS
    *** times: 0+ 5+++ 30++ min
    *** source: 16508002-Fig-5a
  *** Braf[Ab]IP IVKA(Mek1,Erk2,MBP)[32P-ATP] is increased irt Ngf (times)
    *** cells: PC6 in BMLS
    *** times: 0 10+ 15+ 60+ min
    *** partially reqs: Rin1 [RNAi]
    *** source: 16157584-Fig-7b
  *** Braf[phosAb] phos(S446)[phosAb] is increased irt Ngf (times)
    *** cells: PC6 in BMLS
    *** times: 0 10+ 15+++ 60++ min
    *** partially reqs: Rin1 [RNAi]
    *** source: 16157584-Fig-7a
*** Cbl--
  *** Cbl[Ab] copptby[WB] CrkL[Ab] is unchanged irt Ngf (times)
    *** cells: PC12 in BMLS
    *** times: 0 5 10 min
    *** source: 11466412-Fig-4c
  *** Cbl[Ab]IP IVLKA(PtdIns)[TLC] is unchanged irt Ngf (5 min)
    *** cells: PC12 in BMLS
    *** source: 8550620-Fig-2
  *** Creb1[phosAb] phos(S133)[phosAb] is increased irt Ngf (15 min)
    *** cells: PC12 in BMLS
    *** unaffected by: SB203580 [pretreatment]
    *** unaffected by: PD98059 [pretreatment]
    *** partially inhibited by: Ro318220 [pretreatment]
    *** source: 9687510-Fig-13a
*** Crk--
*** CrkL--
*** Csk----
  *** Csk[Ab] copptby[WB] Matk[Ab] is unchanged irt Ngf (10 min)
    *** cells: PC12 in BMLS
    *** source: 10329710-Fig-1d
  *** Csk[Ab] copptby[WB] Trka[Ab] is unchanged irt Ngf (10 min)
    *** cells: PC12 in BMLS
    *** source: 10329710-Fig-1d
*** Efs--
  *** Efs[Ab] copptby[WB] Crk[Ab] is increased irt Ngf (times)
    *** cells: PC12 in BMLS
    *** times: 0+ 10++ 30+++ min
    *** source: 11278445-Fig-5d
*** EgfR--
  *** EgfR[Ab] copptby[WB] CrkL[Ab] is unchanged irt Ngf (times)
    *** cells: PC12 in BMLS
    *** times: 0 5 10 min
    *** source: 11466412-Fig-4c
*** Egr1--
*** Elk1--
*** Erk1--
*** Erk2--
*** Erk5--
  *** Erk5[phosAb] phos(sitenr)[phosAb] is increased irt Ngf (tnr)
    *** cells: PC6 in BMLS
    *** source: 16157584-Fig-1d
*** Erks--
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Ngf (times)
    *** cells: PC6 in BMLS
    *** times: 0 5++ 15+++ 60+ min
    *** does not req: Rin1 [RNAi]
    *** source: 16157584-Fig-3a
  *** Erks[phosAb] phos(TEY)[phosAb] is increased irt Ngf (tnr)
    *** cells: PC6 in BMLS
    *** source: 16157584-Fig-1d
*** Fos--
*** Foxo1--
*** Foxo3--
*** Foxo4--
  *** Foxo4[phosAb] phos(sitenr)[phosAb] is increased irt Ngf (10 min)
    *** cells: PC12 in BMS
    *** inhibited by: Wortmannin [pretreatment]
    *** inhibited by: LY294002 [pretreatment]
    *** unaffected by: PD98059 [pretreatment]
    *** unaffected by: Rapamycin [pretreatment]
    *** source: 11953455-Fig-9c
  *** Foxo4[phosAb] phos(sitenr)[phosAb] is increased irt Ngf (times)
    *** cells: PC12 in BMS
    *** times: 0 2++ 5++ 10++ 20++ 40+ min
    *** source: 11953455-Fig-9a
*** Frs2--
  *** Frs2[Ab] copptby[WB] Crk[Ab] is increased irt Ngf (times)
    *** cells: PC12 in BMLS
    *** times: 0 2 5+ 15+ 30+ 60+ min
    *** source: 11278445-Fig-8a
  *** xFrs2[Ab] copptby[WB] Crk[Ab] is increased irt Ngf (times)
    *** cells: PC12<xFrs2> in BMLS
    *** times: 0 10+ 30+ 60+ min
    *** inhibited by: xFrs2(Y436F) [substitution]
    *** unaffected by: xFrs2(Y192F/Y306F/Y349F/Y392F) [substitution]
    *** source: 11278445-Fig-9
  *** Frs2[Ab]IP prot-exp[WB] is unchanged irt Ngf (times)
    *** cells: PC12 in BMLS
    *** times: 0+ 2+ 5+ 15+ 30+ 60+ min
    *** source: 11278445-Fig-8b
*** Gab1--
*** Gab2--
  *** Gab2[Ab] copptby[WB] CrkL[Ab] is increased irt Ngf (times)
    *** cells: PC12 in BMLS
    *** times: 0 2+ 5+ 10+ 30++ 60++ min
    *** source: 11466412-Fig-4d
  *** Gab2[Ab] copptby[WB] CrkL[Ab] is increased irt Ngf (times)
    *** cells: PC12 in BMLS
    *** times: 0+ 5++ 10++ min
    *** source: 11466412-Fig-4c
*** Grb2--
*** Hd--
  *** Hd[Ab] copptby[WB] Trka[Ab] is increased irt Ngf (15 min)
    *** cells: PC12 in BMLS
    *** source: 11733534-Fig-3d
*** Hras--
  *** Hspb1[phosAb] phos(S82)[phosAb] is increased irt Ngf (times)
    *** cells: PC6 in BMLS
    *** times: 0 5+ 15+ 60+ min
    *** reqs: Rin1 [RNAi]
    *** source: 16157584-Fig-3a
*** Ikba--
*** Ikk1--
*** Ikk2--
*** Irak1--
  *** Irak1[Ab] copptby[WB] Myd88[Ab] is increased irt Ngf (times)
    *** cells: PC12 in BMS
    *** times: 0 1++ 2+ 5 15 30 min
    *** source: 12034707-Fig-2b
*** Jnks--
*** Jun--
  *** Jun-gene mRNA[Northern] is increased irt Ngf (30 min)
    *** cells: PC12 in BMS
    *** source: 1710174-Fig-2b
  *** xJun(TAD)[Gal4-DBD] Gal4-reporter[Luc] is unchanged irt Ngf (tnr)
    *** cells: PC12 in BMLS
    *** source: 9560161-Fig-2b
*** Matk--
  *** Matk[Ab] copptby[WB] Csk[Ab] is unchanged irt Ngf (10 min)
    *** cells: PC12 in BMLS
    *** source: 10329710-Fig-1c
*** Mek12s--
*** Mekk1--
  *** Mekk1[Ab]IP IVKA(Mek1)[32P-ATP] is detectable-but unchanged irt Ngf (times)
    *** cells: PC12 in BMS
    *** times: 0+ 1+ 2+ 5+ 10+ 20+ 45+ 90+ 180+ min
    *** source: 8647237-Fig-1b
*** Mkk36s--
  *** Mkk36s[phosAb] phos(SVAKT)[phosAb] is increased irt Ngf (tnr)
    *** cells: PC6 in BMLS
    *** source: 16157584-Fig-1d
  *** Msk1[Ab]IP IVKA(Crosstide)[32P-ATP] is increased irt Ngf (15 min)
    *** cells: PC12 in BMLS
    *** unaffected by: SB203580 [pretreatment]
    *** unaffected by: PD98059 [pretreatment]
    *** inhibited by: PD98059 + SB203580 [pretreatment]
    *** source: 9687510-Fig-13b
*** Myd88--
*** Nfkb--
  *** Nfkb-reporter[Luc] is increased irt Ngf (4 hr)
    *** cells: HEK293<xIrak1><xNgfR> in BMS
    *** reqs: xIrak1 [omission]
    *** reqs: xNgfR [omission]
    *** source: 12034707-Fig-6a
  *** Nfkb-reporter[Luc] is increased irt Ngf (4 hr)
    *** cells: HEK293I1A<Irak1~null><xIrak1><xNgfR> in BMS
    *** reqs: xIrak1 [omission]
    *** reqs: xNgfR [omission]
    *** source: 12034707-Fig-5c
  *** Nfkb-reporter[Luc] is increased irt Ngf (4 hr)
    *** cells: PC12 in BMS
    *** enhanced by: K252a [pretreatment]
    *** source: 12034707-Fig-4a
  *** Nfkb-reporter[Luc] is increased irt Ngf (4 hr)
    *** cells: PC12<xIrak1> in BMS
    *** enhanced by: K252a [pretreatment]
    *** source: 12034707-Fig-4a
  *** Nfkb-reporter[Luc] is increased irt Ngf (4 hr)
    *** cells: PC12<xIrak1> in BMS
    *** inhibited by: xIrak1(mnr)"KD" [substitution]
    *** source: 12034707-Fig-4a
  *** Nfkb-reporter[Luc] is increased irt Ngf (5 hr)
    *** cells: rSchwann in BMLS
    *** reqs: Traf6 [KO]
    *** source: 15548667-Fig-1a
  *** Nfkb-reporter[Luc] is increased irt Ngf (24 hr)
    *** cells: HEK293<xNgfR><xRipk2> in BMS
    *** reqs: both [omissions]
    *** source: 11487608-Fig-4b
  *** Nfkb-reporter[Luc] is increased irt Ngf (24 hr)
    *** cells: rSchwann in BMS
    *** inhibited by: xRipk2(mnr)"DN" [addition]
    *** source: 11487608-Fig-5c
  *** Nfkb-reporter[Luc] is increased irt Ngf (times)
    *** cells: PC12 in BMS
    *** times: 0 30 60 180++ 360+ min
    *** enhanced by: K252a [pretreatment]
    *** source: 12034707-Fig-4b
  *** Nfkb-reporter[Luc] is unchanged irt Ngf (24 hr)
    *** cells: HEK293 in BMS
    *** unaffected by: xNgfR [addition]
    *** source: 11487608-Fig-4b
*** Nfkb1--
  *** Nfkb1[Ab] oligo-binding[EMSA] is increased irt Ngf (2 hr)
    *** cells: Lcells<xNgfR> in BMS
    *** source: 8614802-Fig-3
*** Ngf--
  *** Ngf[125I] copptby[Xlink] xTrkb[Ab] is undetectable
    *** cells: NIH3T3<xTrkb> in BMS
    *** source: 1849459-Fig-3
  *** Ngf[125I] receptor-binding[RIA] is undetectable
    *** cells: NIH3T3<xTrkb> in BMS
    *** source: 1849459-Fig-1
*** NgfR--
  *** xNgfR[Ab] copptby[WB] xRipk2[Ab] is increased irt Ngf (times)
    *** cells: HEK293<xNgfR><xRipk2> in BMS
    *** times: 0 1 2+ 5+ 10 20 30 min
    *** source: 11487608-Fig-4a
  *** xNgfR[tAb] copptby[WB] xArms[Ab] is detectable
    *** cells: HEK293<xNgfR><xArms> in BMS
    *** source: 1150334-Fig-4a
  *** xP38a[tAb]IP IVKA(Atf2)(sitenr)[phosAb] is increased irt Ngf (tnr)
    *** cells: PC6 in BMLS
    *** source: 16157584-Fig-4b
  *** xP38d[tAb]IP IVKA(Atf2)(sitenr)[phosAb] is unchanged irt Ngf (tnr)
    *** cells: PC6 in BMLS
    *** source: 16157584-Fig-4b
  *** xP38g[tAb]IP IVKA(Atf2)(sitenr)[phosAb] is unchanged irt Ngf (tnr)
    *** cells: PC6 in BMLS
    *** source: 16157584-Fig-4b
*** P38s--
*** Pi3k--
  *** Pi3k[Ab] copptby[WB] Gab1[Ab] is detectable-but unchanged irt Ngf (times)
    *** cells: PC12 in BMLS
    *** times: 0+ 1+ 5+ 10+ 20+ 60+ min
    *** source: 9356464-Fig-1
*** Pik3rs--
  *** Pik3rs[Ab]IP Yphos[pYAb] is increased itpo xNgfR
    *** cells: PC12 in BMS
    *** source: 11312266-Fig-7b
*** Plcg1--
*** Pxn--
*** Raf1--
  *** Raf1[Ab] snaggedby[WB] rRheb{GMPPNP}[GST] is increased irt Ngf (5 min)
    *** cells: PC12 in BMS
    *** bkg inhibited by: rRheb{GDP} [substitution]
    *** source: 9001246-Fig-3c
  *** Raf1[Ab] snaggedby[WB] rRheb{GMPPNP}[GST] is increased irt Ngf (5 min)
    *** cells: PC12 in BMS
    *** inhibited by: rRheb{GDP} [substitution]
    *** source: 9001246-Fig-3c
*** Rap1a--
*** RapGef1--
*** Rasa1--
  *** Rasa1[Ab] copptby[WB] Shc1[Ab] is increased irt Ngf (5 min)
    *** cells: PC12<xTrka> in BMS
    *** source: 8155326-Fig-3e
*** RasGrf1--
  *** xRasGrf1[tAb]IP Yphos[pYAb] is detectable
    *** cells: COS7<xTrka><xRasGrf1> in BMS
    *** enhanced by: xRasGrf1(29-528) [substitution]
    *** source: 10691301-Fig-7
  *** xRasGrf1[tAb]IP Yphos[pYAb] is detectable
    *** cells: COS7<xTrka><xRasGrf1> in BMS
    *** partially inhibited by: xTrka(K547A) [substitution]
    *** source: 10691301-Fig-7
*** Rel--
  *** Rel[Ab] oligo-binding[EMSA] is increased irt Ngf (2 hr)
    *** cells: Lcells<xNgfR> in BMS
    *** source: 8614802-Fig-3
*** Rela--
*** Rin1--
*** Ripk1--
  *** Ripk1[Ab] copptby[WB] NgfR[Ab] is unchanged irt Ngf (10 min)
    *** cells: rSchwann in BMS
    *** source: 11487608-Fig-2b
*** Ripk2--
*** Rit1--
  *** Rsk1[Ab]IP IVKA(Crosstide)[32P-ATP] is increased irt Ngf (15 min)
    *** cells: PC12 in BMLS
    *** unaffected by: SB203580 [pretreatment]
    *** unaffected by: PD98059 [pretreatment]
    *** unaffected by: PD98059 + SB203580 [pretreatment]
    *** source: 9687510-Fig-13b
*** S6ks--
  *** S6ks[Ab] phos[WBMS] is increased irt Ngf (times)
    *** cells: PC12 in BMLS
    *** times: 0+ 1+ 5++ 10++ 20++ min
    *** source: 10601297-Fig-4b
  *** S6ks[Ab] phos[WBMS] is increased irt Ngf (times)
    *** cells: PC12<xGab1> in BMLS
    *** times: 0+ 1+ 5++ 10++ 20++ min
    *** source: 10601297-Fig-4b
  *** S6ks[Ab] phos[WBMS] is increased irt Ngf (tnr)
    *** cells: PC12<xGab1> in BMLS
    *** source: 10601297-Fig-4a
*** Sh2d3c--
  *** Sh2d3c[Ab]IP phos[WBMS-PPase] is increased irt Ngf (3 min)
    *** cells: PC12 in BMLS
    *** source: 10692442-Fig-5a
*** Shc1--
*** Shp2--
  *** Shp2[Ab] copptby[WB] CrkL[Ab] is detectable-but unchanged irt Egf (times)
    *** cells: PC12 in BMLS
    *** times: 0+ 5+ 10+ min
    *** source: 11466412-Fig-4c
  *** Shp2[Ab] copptby[WB] CrkL[Ab] is detectable-but unchanged irt Ngf (times)
    *** cells: PC12 in BMLS
    *** times: 0+ 5+ 10+ min
    *** source: 11466412-Fig-4c
  *** Shp2[Ab] copptby[WB] Gab1[Ab] is increased irt Ngf (times)
    *** cells: PC12 in BMLS
    *** times: 0+ 1+ 5++ 10++ 20++ 60++ min
    *** source: 9356464-Fig-1
*** Sos1--
  *** Sos1[Ab] phos[WBMS] is increased irt Ngf (times)
    *** cells: PC12 in BMLS
    *** times: 0 2++ 5+++ 15+++ 30+ 60+ min
    *** source: 11278445-Fig-4a
*** Sqstm1--
*** Trka--
  *** Trka[Ab] copptby[WB] Crk[Ab] is unchanged irt Ngf (times)
    *** cells: PC12 in BMLS
    *** times: 0 2 5 15 30 60 min
    *** source: 11278445-Fig-6
  *** Trka[Ab] copptby[WB] CrkL[Ab] is increased irt Ngf (times)
    *** cells: PC12 in BMLS
    *** times: 0 2+ 5 10 30 60 min
    *** source: 11466412-Fig-4d
  *** Trka[Ab] copptby[WB] Csk[Ab] is unchanged irt Ngf (10 min)
    *** cells: PC12 in BMLS
    *** source: 10329710-Fig-1a 
  *** xTrka[Ab] copptby[WB] Rgs19ip1[Ab] is detectable-but unchanged irt Ngf (times)
    *** cells: PC12<xTrka> in BMS
    *** times: 0+ 10+ 30+ min
    *** source: 11251075-Fig-4a
  *** xTrka[Ab] copptby[WB] Shc1[Ab] is increased irt Ngf (5 min)
    *** cells: PC12<xTrka> in BMS
    *** source: 8155326-Fig-3b
  *** xTrka[Ab] copptby[WB] Shc1[Ab] is increased irt Ngf (tnr)
    *** cells: NIH3T3<xTrka> in BMS
    *** inhibited by: xTrka(Y496F) [substitution]
    *** inhibited by: xTrka(Y496F/Y791F) [substitution]
    *** unaffected by: xTrka(Y791F) [substitution]
    *** inhibited by: xTrka(K544N)"KD" [substitution]
    *** source: 8155326-Fig-6a
  *** xTrka[Ab] Yphos[pYAb-ppt] is detectable
    *** cells: NIH3T3<xTrka> in BMS
    *** source: 1831195-Fig-1
  *** Trka[Ab]IP phos(Y496)[phosAb] is increased irt Ngf (times)
    *** cells: PC12 in BMLS
    *** times: 0 5+ 10+ 30+ 60+ min
    *** source: 11466412-Fig-4e
  *** Trka[Ab]IP prot-exp[WB] is unchanged irt Ngf (times)
    *** cells: PC12 in BMLS
    *** times: 0+ 2+ 5+ 15+ 30+ 60+ min
    *** source: 11278445-Fig-7b
  *** Trka[Ab]IP ubiq[UbAb] is unchanged irt Ngf (times)
    *** cells: PC12 in BMLS
    *** times: 0 2 5 15 30 60 min
    *** source: 11278445-Fig-7b
  *** xTrka[Ab]IP Yphos[pYAb] is detectable
    *** cells: HEK293T<xAbl1><xTrka> in BMS
    *** inhibited by: xTrka(K538A) [substitution]
    *** source: 10679771-Fig-2
  *** xTrka[tAb] snaggedby[WB] rEif3a[GST] is detectable
    *** cells: SF9<xTrka> in BMS "treated with Ngf for 10 min"
    *** source: 10691301-Fig-3
  *** xTrka[tAb] snaggedby[WB] rIna[GST] is detectable
    *** cells: COS7<xTrka> in BMS
    *** inhibited by: xTrka(K547A) [substitution]
    *** source: 10691301-Fig-6a
  *** xTrka[tAb] snaggedby[WB] rIna[GST] is detectable
    *** cells: SF9<xTrka> in BMS "treated with Ngf for 10 min"
    *** source: 10691301-Fig-3
  *** xTrka[tAb] snaggedby[WB] rPlcg1[GST] is detectable
    *** cells: SF9<xTrka> in BMS "treated with Ngf for 10 min"
    *** source: 10691301-Fig-3
  *** xTrka[tAb] snaggedby[WB] rPrph[GST] is detectable
    *** cells: COS7<xTrka> in BMS
    *** inhibited by: xTrka(K547A) [substitution]
    *** source: 10691301-Fig-6a
  *** xTrka[tAb] snaggedby[WB] rPrph[GST] is detectable
    *** cells: SF9<xTrka> in BMS "treated with Ngf for 10 min"
    *** source: 10691301-Fig-3
  *** xTrka[tAb] snaggedby[WB] rPsmb6[GST] is detectable
    *** cells: COS7<xTrka> in BMS
    *** inhibited by: xTrka(K547A) [substitution]
    *** source: 10691301-Fig-6a
  *** xTrka[tAb] snaggedby[WB] rPsmb6[GST] is detectable
    *** cells: SF9<xTrka> in BMS "treated with Ngf for 10 min"
    *** source: 10691301-Fig-3
  *** xTrka[tAb] snaggedby[WB] rRasGrf1(29-528)[GST] is detectable
    *** cells: COS7<xTrka> in BMS
    *** partially inhibited by: xTrka(K547A) [substitution]
    *** source: 10691301-Fig-6a
  *** xTrka[tAb] snaggedby[WB] rRasGrf1(29-528)[GST] is detectable
    *** cells: SF9<xTrka> in BMS "treated with Ngf for 10 min"
    *** source: 10691301-Fig-3
*** Trkb--
  *** xTrkb[125I] boundby[Xlink] rNgf[125I] is undetectable
    *** cells: COS<xTrkb> in BMS
    *** source: 1710174-Fig-3
