=============
Transcription
=============

not Parp14--

  *** Irf1-gene mRNA[RTPCR] is increased irt Ifng (tnr)
    *** cells: M12 in BMS
    *** does not req: Parp14 [RNAi]
    *** source: 16537510-Fig-4f
  *** Irf1-gene mRNA[RTPCR] is increased irt Ifng (tnr)
    *** cells: M12 in BMS
    *** unaffected by: xParp14(1216-1817) [substitution]
    *** source: 16537510-Fig-3e

not Pias1--

  *** Irf1-gene mRNA[RTPCR] is increased irt Ifng (times)
    *** cells: mBMMs in BMS
    *** times: 0 2++ 4++ 6+ hr
    *** unaffected by: Pias1 [KO]
    *** source: 15311277-Fig-2a
  *** Irf1-gene mRNA[RTPCR] is increased irt Ifng (times)
    *** cells: mEFs in BMS
    *** times: 0 60+ 180++ 360++ min
    *** repressed by: Pias1 [KO]
    *** source: 17606919-Fig-4c

not Pias4--

  *** Irf1-gene mRNA[RTPCR] is increased irt Ifng (times)
    *** cells: mBMDCs in BMS
    *** times: 0 60++ 180++ 360+ min
    *** repressed by: Pias4 [KO]
    *** source: 17606919-Fig-5c

Pkr--

  *** Irf1-gene promo-reporter[Luc] is increased irt Ifng (4 hr)
    *** cells: mEFs in BMLS
    *** unaffected by: xPkr [addition]
    *** inhibited by: xPkr(K296R)"KD" [addition]
    *** source: 9029059-Fig-1a
  *** Irf1-gene promo-reporter[Luc] is increased irt Ifng (4 hr)
    *** cells: mEFs<Pkr~null><xPkr> in BMLS
    *** reqs: xPkr [omission]
    *** inhibited by: xPkr(K296R)"KD" [addition]
    *** source: 9029059-Fig-1b

Stat1--

  *** Irf1-gene mRNA[RTPCR] is increased irt Ifng (times)
    *** cells: mEFs<Stat1~null><xStat1> in BMS
    *** times: 0 2++ 6+ 12+ hr
    *** inhibited by: xStat1(K703R) [substitution]
    *** comment: substitution with xStat1(K703R) shows a delayed response at 12 hr
    *** unaffected by: xStat1(E705A) [substitution]
    *** source: 16857984-Fig-6a

chemicals

  *** Irf1-gene mRNA[RPA] is increased irt Ifng (15 hr)
    *** cells: 2FTGH in BMS
    *** unaffected by: CytochalasinD [pretreatment]
    *** unaffected by: Nocodazole [pretreatment]
    *** source: 11350940-Fig-1a

no extras

  *** Irf1-gene mRNA[Northern] is increased irt Ifng (tnr)
    *** cells: BJAB in BMS
    *** source: 9133417-Fig-5c
  *** Irf1-gene mRNA[RTPCR] is increased irt Ifng (times)
    *** cells: mBMMs in BMS
    *** times: 0 10 30+ 45+ 60++ 90+ min
    *** source: 17293456-Fig-1b
  *** Irf1-gene mRNA[RTPCR] is increased irt Ifng (times)
    *** cells: mBMMs in BMS "purified-nuclei"
    *** times: 0 10 30+ 45++ 60++ 90+ min
    *** source: 17293456-Fig-1b
  *** Irf1-gene mRNA[Northern] is increased irt Ifng (28 hr)
    *** cells: BJAB in BMS
    *** unaffected by: IL4 [cotreatment]
    *** source: 10201928-Fig-1a


===========
Translation
===========

Stat1--

  *** Irf1[Ab] prot-exp[WB] is increased irt Ifng (60 min)
    *** cells: mEFs in BMS
    *** reqs: Stat1 [KO]
    *** source: 17293456-Fig-3g
  *** Irf1[Ab] prot-exp[WB] is increased irt Ifng (times)
    *** cells: mBMMs in BMS
    *** times: 0 30+ 120++ 240++ min
    *** partially inhibited by: xStat1(S727A) [addition]
    *** source: 17293456-Fig-4e

no extras

  *** Irf1[Ab] prot-exp[WB] is increased irt Ifng (90 min)
    *** cells: mPECs in BMS
    *** does not req: Pkr [KO]
    *** source: 11694524-Fig-6
  *** Irf1[Ab] prot-exp[WB] is increased irt Ifng (times)
    *** cells: mBMMs in BMS
    *** times: 0 10 30 45+ 60++ 90++ 120++ 150++ min
    *** source: 17293456-Fig-1c
  *** Irf1[Ab] prot-exp[WB] is increased irt Ifng (times)
    *** cells: mBMMs in BMS "nuclear-extracts"
    *** times: 0 30 60+ min
    *** source: 17293456-Fig-6
  *** Irf1[Ab] prot-exp[WB] is increased irt Ifng (times)
    *** cells: mHepatocytes in BMLS
    *** times: 0 30 60+ 480+ min
    *** source: 15246962-Fig-4
  *** Irf1[Ab] prot-exp[WB] is increased irt Ifng (times)
    *** cells: mKupfferCells in BMLS
    *** times: 0+ 30+ 60+ 480++ min
    *** source: 15246962-Fig-4
  *** Irf1[Ab] prot-exp[WB] is increased irt Ifng (times)
    *** cells: mSinusoidalEndothelialCells in BMLS
    *** times: 0 30+ 60+ 480+ min
    *** source: 15246962-Fig-4

=====================
Transcription Factors
=====================

  *** Stat1[Ab] boundto(Irf1-gene)[ChIP] is increased irt Ifng (times)
    *** cells: mBMMs in BMS
    *** times: 0 20++ 60+ min
    *** unaffected by: Pias1 [KO]
    *** source: 15311277-Fig-4b
  *** Stat1[Ab] boundto(Irf1-gene)[ChIP] is increased irt Ifng (times)
    *** cells: mEFs in BMS
    *** times: 0 30+ 60+ min
    *** does not req: Irf1 [KO]
    *** source: 17293456-Fig-3f
