=============
Transcription
=============

Hmgb1-- and/or Hmgb2-- and/or Hmgb3--

  *** ProTnf-gene mRNA[RTPCR] is increased irt PolyIC-transfection (times)
    *** cells: mFLcDCs in BMS
    *** times: 0 3+ 6++ hr
    *** partially reqs: Hmgb1 [KO]
    *** source: 19890330-Fig-3a
  *** ProTnf-gene mRNA[RTPCR] is increased irt PolyIC-transfection (times)
    *** cells: RAW2647 in BMS
    *** times: 0 3+ 6+ hr
    *** partially reqs: Hmgb1 and/or Hmgb2 and/or Hmgb3 [KO]
    *** source: 19890330-Fig-S5a

Peli1--

  *** ProTnf-gene mRNA[RTPCR] is increased irt PolyIC (times)
    *** cells: mBMDCs in BMLS
    *** times: 0 2++ 4+ hr
    *** reqs: Peli1 [KO]
    *** source: 19734906-Fig-2d
  *** ProTnf-gene mRNA[RTPCR] is increased irt PolyIC (times)
    *** cells: mEFs in BMLS
    *** times: 0 2++ 4+ hr
    *** reqs: Peli1 [KO]
    *** source: 19734906-Fig-2a
  *** ProTnf-gene mRNA[RTPCR] is increased irt PolyIC (times)
    *** cells: mSpBCs in BMLS
    *** times: 0 2++ 4+ hr
    *** reqs: Peli1 [KO]
    *** source: 19734906-Fig-2e

Pkr--  ????

  *** ProTnf-gene mRNA[RTPCR] is increased irt PolyIC (2 hr)
    *** cells: BEAS2B in BMS
    *** inhibited by: xPkr(del(361-366))"CIA" [addition]
    *** source: 12055262-Fig-3b
  *** ProTnf-gene mRNA[RPA] is increased irt PolyIC-transfection (4 hr)
    *** cells: mEFs in BMLS
    *** does not req: Pkr [KO]
    *** source: 11113181-Fig-7a

Trif--

  *** ProTnf-gene mRNA[RTPCR] is increased irt PolyIC (2 hr)
    *** cells: mBMMs in BMS "immortalized"
    *** reqs: Trif [KO]
    *** source: 22065573-Fig-1b

chemicals

  *** ProTnf-gene mRNA[RTPCR] is increased irt PolyIC (2 hr)
    *** cells: mBMMs in BMS "immortalized"
    *** unaffected by: JSH23 [pretreatment]
    *** source: 22065573-Fig-1b
  *** ProTnf-gene mRNA[RTPCR] is increased irt PolyIC (2 hr)
    *** cells: mBMMs in BMS "immortalized"
    *** unaffected by: JSH23 [pretreatment]
    *** unaffected by: CHX [pretreatment]
    *** source: 22065573-Fig-2b
  *** ProTnf-gene mRNA[RTPCR] is increased irt PolyIC (2 hr)
    *** cells: THP1 in BMS "differentiated with Csf1"
    *** unaffected by: JSH23 [pretreatment]
    *** source: 22065573-Fig-1c
  *** ProTnf-gene mRNA[RTPCR] is increased irt PolyIC (2 hr)
    *** cells: BEAS2B in BMS
    *** inhibited by: anti-MsR1 [pretreatment]
    *** source: 17709607-Fig-2a
  *** ProTnf-gene mRNA[RTPCR] is increased irt PolyIC (2 hr)
    *** cells: BEAS2B in BMS
    *** inhibited by: DextranSulfate [cotreatment]
    *** inhibited by: Fucoidan [cotreatment]
    *** inhibited by: Ac-LDL [cotreatment]
    *** unaffected by: Heparin [cotreatment]
    *** unaffected by: Fetuin [cotreatment]
    *** source: 17709607-Fig-1a
  *** ProTnf-gene mRNA[RTPCR] is increased irt PolyIC (2 hr)
    *** cells: hBECs in BMLS
    *** inhibited by: anti-MsR1 [pretreatment]
    *** source: 17709607-Fig-2b
  *** ProTnf-gene mRNA[RTPCR] is increased irt PolyIC (2 hr)
    *** cells: hBECs in BMLS
    *** inhibited by: DextranSulfate [cotreatment]
    *** source: 17709607-Fig-1c
  *** ProTnf-gene mRNA[RTPCR] is increased irt PolyIC (2 hr)
    *** cells: mBMMs in BMS
    *** unaffected by: SmacMimetic [pretreatment]
    *** source: 19898473-Fig-6a

no extras

  *** ProTnf-gene mRNA[RTPCR] is increased irt PolyIC (2 hr)
    *** cells: BEAS2B in BMS
    *** source: 12055262-Fig-1c
  *** ProTnf-gene mRNA[RTPCR] is increased irt PolyIC (2 hr)
    *** cells: BEAS2B in BMS
    *** source: 12055262-Fig-1d
  *** ProTnf-gene mRNA[RTPCR] is increased irt PolyIC (times)
    *** cells: BEAS2B in BMS
    *** times: 0 30 60+ 120++ 240+ 480 min
    *** source: 12055262-Fig-1b
  *** ProTnf-gene mRNA[RTPCR] is increased irt PolyIC (times)
    *** cells: hLECs in BMS
    *** times: 0 30+ 60+ 120+ 240+ 480 min
    *** source: 12055262-Fig-1a
  *** ProTnf-gene mRNA[RTPCR] is unchanged irt PolyC (2 hr)
    *** cells: BEAS2B in BMS
    *** source: 12055262-Fig-1c
  *** ProTnf-gene mRNA[RTPCR] is unchanged irt PolyI (2 hr)
    *** cells: BEAS2B in BMS
    *** source: 12055262-Fig-1c

===========
Translation
===========

  *** Tnf[Ab] secretion[ELISA] is increased irt PolyIC (4 hr)
    *** cells: mPECs in BMS
    *** inhibited by: Unc93b1(H412R) [fmut]
    *** source: 16415873-Fig-1a

=========
Secretion
=========

  *** Tnf[Ab] secretion[ELISA] is increased irt PolyIC (24 hr)
    *** cells: hMDDCs in BMS
    *** inhibited by: Z-FA-FMK [pretreatment]
    *** source: 23255358-Fig-2e
  *** xTnf[Ab] prot-exp[FACS] is increased irt PolyIC (tnr)
    *** cells: mBMDCs in BMS
    *** unaffected by: xUnc93b1 [addition]
    *** inhibited by: xUnc93b1(H412R) [addition]
    *** source: 16415873-Fig-4a
