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Fak2 kinase activity is increased itpo Src
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  *** xFak2[Ab]IP IVKA(PolyGluTyr)[32P-ATP] is increased itpo xSrc
    *** cells: HELA in BMS
    *** unaffected by: xSrc(Y530F) [substitution]
    *** inhibited by: xSrc(K297R)"KD" [substitution]
    *** inhibited by: xSrc(K297R/Y530F) [substitution]
    *** inhibited by: xFak2(K457A/D567A)"KD" [substitution]
    *** source: 14963038-Fig-4a

  *** xFak2(K457A)[Ab]IP Yphos[pYAb] is increased itpo xSrc
    *** cells: HEK293T in BMS
    *** source: 10085136-Fig-2a
  *** xFak2(K457A)[Ab]IP Yphos[pYAb] is increased itpo xSrc
    *** cells: HEK293T in BMS
    *** unaffected by: xFak2(Y402F/Y881F) [substitution]
    *** source: 10085136-Fig-2c

  *** xFak2[phosAb] phos(Y402)[phosAb] is increased itpo xSrc
    *** cells: HELA in BMS
    *** unaffected by: xSrc(Y530F) [substitution]
    *** inhibited by: xSrc(K297R)"KD" [substitution]
    *** inhibited by: xSrc(K297R/Y530F) [substitution]
    *** unaffected by: xFak2(K457A/D567A)"KD" [substitution]
    *** source: 14963038-Fig-4a
  *** xFak2[phosAb] phos(Y579)[phosAb] is increased itpo xSrc
    *** cells: HELA in BMS
    *** unaffected by: xSrc(Y530F) [substitution]
    *** inhibited by: xSrc(K297R)"KD" [substitution]
    *** inhibited by: xSrc(K297R/Y530F) [substitution]
    *** unaffected by: xFak2(K457A/D567A)"KD" [substitution]
    *** source: 14963038-Fig-4a
  *** xFak2[phosAb] phos(Y580)[phosAb] is increased itpo xSrc
    *** cells: HELA in BMS
    *** unaffected by: xSrc(Y530F)"CA" [substitution]
    *** inhibited by: xSrc(K297R)"KD" [substitution]
    *** inhibited by: xSrc(K297R/Y530F) [substitution]
    *** unaffected by: xFak2(K457A/D567A)"KD" [substitution]
    *** source: 14963038-Fig-4a
  *** xFak2[phosAb] phos(Y881)[phosAb] is increased itpo xSrc
    *** cells: HELA in BMS
    *** unaffected by: xSrc(Y530F)"CA" [substitution]
    *** inhibited by: xSrc(K297R)"KD" [substitution]
    *** inhibited by: xSrc(K297R/Y530F) [substitution]
    *** unaffected by: xFak2(K457A/D567A)"KD" [substitution]
    *** source: 14963038-Fig-4a

  *** Fak2[Ab] copptby[WB] Src[Ab] is detectable-but unchanged irt Egf (15 min)
    *** cells: A431 in BMS
    *** source: 14963038-Fig-7c

  *** xFak2[tAb] copptby[WB] Src[Ab] is detectable
    *** cells: mBMPOs in BMS
    *** unaffected by: xFak2(K457A)"KD" [substitution]
    *** inhibited by: xFak2(Y402F) [substitution]
    *** source: 12514172-Fig-5a
  *** Fak2[Ab] copptby[WB] Src[Ab] is detectable
    *** cells: mBMPOs in BMS
    *** enhanced by: xFak2(WT) [addition]
    *** enhanced by: xFak2(K457A)"KD" [addition]
    *** unaffected by: xFak2(Y402F) [addition]
    *** comment: enhance coppt probably due to increase in xFak2 protein
    *** source: 12514172-Fig-5a

  *** xFak2[Ab] copptby[WB] xSrc(mnr)"CA"[Ab] is detectable
    *** cells: HELA<xStat3> in BMS
    *** source: 14963038-Fig-3
  *** xSrc(mnr)"CA"[Ab] copptby[WB] xFak2[Ab] is detectable
    *** cells: HELA<xStat3> in BMS
    *** source: 14963038-Fig-3



  *** Src[Ab]IP phos(Y416)[phosAb] is increased itpo xFak2
    *** cells: HEK293T in BMS
    *** inhibited by: xFak2(Y402F) [substitution]
    *** unaffected by: xFak2(Y881F) [substitution]
    *** inhibited by: xFak2(mnr)"KD" [substitution]
    *** source: 10329689-Fig-1c

  *** Src[Ab]IP Yphos[pYAb] is detectable
    *** cells: mBMPOs in BMS
    *** unaffected by: xFak2(WT) [addition]
    *** unaffected by: xFak2(K457A)"KD" [addition]
    *** unaffected by: xFak2(Y402F) [addition]
    *** source: 12514172-Fig-5b
