{
 
"Egf":{"stype" : "basicOp",
	 "name" : "Egf",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "category" : "Ligand", "spnumber" : "P01133", "hugosym" : "EGF", "contains" : [ "Epidermal growth factor", "Urogastrone" ], "synonyms" : [ "Pro-epidermal growth factor", "EGF_HUMAN" ], "sort" : "BProtein" }
},
"EgfR":{"stype" : "basicOp",
	 "name" : "EgfR",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "category" : "Receptor", "spnumber" : "P00533", "hugosym" : "EGFR", "synonyms" : [ "Epidermal growth factor receptor", "ERBB1", "Receptor tyrosine-protein kinase ErbB-1", "EGFR_HUMAN" ], "sort" : "BProtein" }
},
"Gab1":{"stype" : "basicOp",
	 "name" : "Gab1",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "spnumber" : "Q13480", "hugosym" : "GAB1", "synonyms" : [ "GRB2-associated binding protein 1", "GRB2-associated binder-1", "GABI_HUMAN" ], "sort" : "GabS" }
},
"Gab2":{"stype" : "basicOp",
	 "name" : "Gab2",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "spnumber" : "Q9UQC2", "hugosym" : "GAB2", "synonyms" : [ "GRB2-associated binding protein 2", "GRB2-associated binder-2", "pp100", "KIAA0571", "GABJ_HUMAN" ], "sort" : "GabS" }
},
"Gabs":{"stype" : "basicOp",
	 "name" : "Gabs",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "category" : "Family", "members" : [ "Gab1", "Gab2" ], "comment" : "", "sort" : "GabS" }
},
"Hras":{"stype" : "basicOp",
	 "name" : "Hras",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "spnumber" : "P01112", "hugosym" : "HRAS", "synonyms" : [ "GTPase HRas", "Transforming protein p21", "v-Ha-ras Harvey rat sarcoma viral oncogene homolog", "Harvey murine sarcoma virus oncogene", "H-Ras-1", "c-H-ras", "HRAS1", "RASH1", "RASH_HUMAN" ], "sort" : "BProtein" }
},
"Pi3k":{"stype" : "basicOp",
	 "name" : "Pi3k",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "subunits" : [ "Pik3cs", "Pik3rs" ], "comment" : [ "PI3 Kinase is a heterodimer of:", "a p110 catalytic subunit: Pik3ca, Pik3cb, Pik3cd or Pik3cg", "a p85 regulatory subunit: Pik3r1, Pik3r2, or Pik3r3 " ], "sort" : "Composite" }
},
"Pik3c?":{"stype" : "basicOp",
	 "name" : "Pik3c?",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "sort" : "Pik3cS" }
},
"Pik3ca":{"stype" : "basicOp",
	 "name" : "Pik3ca",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "subunitof" : "Pi3k", "spnumber" : "P42336", "hugosym" : "PIK3CA", "synonyms" : [ "Phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha isoform", "PI3-kinase p110 subunit alpha", "PtdIns-3-kinase p110", "Pi3k", "PK3CA_HUMAN" ], "sort" : "Pik3cS" }
},
"Pik3cb":{"stype" : "basicOp",
	 "name" : "Pik3cb",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "subunitof" : "Pi3k", "spnumber" : "P42338", "hugosym" : "PIK3CB", "synonyms" : [ "Phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit beta isoform", "PI3-kinase p110 subunit beta", "PtdIns-3-kinase p110", "Pi3kbeta", "PK3CA_HUMAN" ], "sort" : "Pik3cS" }
},
"Pik3cd":{"stype" : "basicOp",
	 "name" : "Pik3cd",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "subunitof" : "Pi3k", "spnumber" : "O00329", "hugosym" : "PIK3CD", "synonyms" : [ "Phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit delta isoform", "PI3-kinase p110 subunit delta", "PtdIns-3-kinase p110", "Pi3k p110delta", "PK3CA_HUMAN" ], "sort" : "Pik3cS" }
},
"Pik3cg":{"stype" : "basicOp",
	 "name" : "Pik3cg",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "subunitof" : "Pi3k", "spnumber" : "P48736", "hugosym" : "PIK3CG", "synonyms" : [ "Phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit gamma isoform", "PI3-kinase p110 subunit gamma", "PtdIns-3-kinase p110", "Pi3kgamma", "PK3CA_HUMAN" ], "sort" : "Pik3cS" }
},
"Pik3cs":{"stype" : "basicOp",
	 "name" : "Pik3cs",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "category" : "Family", "members" : [ "Pik3ca", "Pik3cb", "Pik3cd", "Pik3cg" ], "sort" : "Pik3cS" }
},
"Pik3r1":{"stype" : "basicOp",
	 "name" : "Pik3r1",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "subunitof" : "Pi3k", "spnumber" : "P27986", "hugosym" : "PIK3R1", "synonyms" : [ "Phosphatidylinositol 3-kinase regulatory alpha subunit", "PI3-kinase p85-alpha subunit", "PtdIns-3-kinase p85-alpha", "GRB1", "P85A_HUMAN" ], "sort" : "Pik3rS" }
},
"Pik3r2":{"stype" : "basicOp",
	 "name" : "Pik3r2",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "subunitof" : "Pi3k", "spnumber" : "O00459", "hugosym" : "PIK3R2", "synonyms" : [ "Phosphatidylinositol 3-kinase regulatory beta subunit", "PI3-kinase p85-beta subunit", "PtdIns-3-kinase p85-beta", "P85B_HUMAN" ], "sort" : "Pik3rS" }
},
"Pik3r3":{"stype" : "basicOp",
	 "name" : "Pik3r3",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "subunitof" : "Pi3k", "spnumber" : "Q92569", "hugosym" : "PIK3R3", "synonyms" : [ "Phosphatidylinositol 3-kinase regulatory gamma subunit", "PI3-kinase", "p85-gamma subunit", "PtdIns-3-kinase p85-gamma", "p55PIK", "P55G_HUMAN" ], "sort" : "Pik3rS" }
},
"Pik3r?":{"stype" : "basicOp",
	 "name" : "Pik3r?",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "sort" : "Pik3rS" }
},
"Pik3rs":{"stype" : "basicOp",
	 "name" : "Pik3rs",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "category" : "Family", "members" : [ "Pik3r1", "Pik3r2", "Pik3r3" ], "sort" : "Pik3rS" }
},
"Sos1":{"stype" : "basicOp",
	 "name" : "Sos1",
	 "modname" : "PROTEINOPS",
	 "metadata" : { "category" : "Guanine Nucleotide Exchange Factor", "spnumber" : "Q07889", "hugosym" : "SOS1", "synonyms" : [ "Son of sevenless protein homolog 1", "SOS-1", "SOS1 guanine nucleotide exchange factor", "Son of sevenless, drosophila homolog 1 ", "SOS1_HUMAN" ], "sort" : "BProtein" }
},

"DAG":{"stype" : "basicOp",
	 "name" : "DAG",
	 "modname" : "CHEMICALOPS",
	 "metadata" : { "sort" : "Chemical" }
},
"cAMP":{"stype" : "basicOp",
	 "name" : "cAMP",
	 "modname" : "CHEMICALOPS",
	 "metadata" : { "sort" : "Chemical" }
},

"EgfR-gene":{"stype" : "basicOp",
	 "name" : "EgfR-gene",
	 "modname" : "GENEOPS",
	 "metadata" : { "sort" : "Gene" }
},
"Erk1-gene":{"stype" : "basicOp",
	 "name" : "Erk1-gene",
	 "modname" : "GENEOPS",
	 "metadata" : { "sort" : "Gene" }
},
"Erk2-gene":{"stype" : "basicOp",
	 "name" : "Erk2-gene",
	 "modname" : "GENEOPS",
	 "metadata" : { "sort" : "Gene" }
},
 
} 
