========================
Ligand/Receptor binding
========================

  *** HgfR[125I] boundby[Xlink] pHgf[125I] is detectable
    *** cells: B5589 in BMLS
    *** source: 1846706-Fig-3b
  *** pHgf[125I] copptby[Xlink] HgfR[Ab] is detectable
    *** cells: B5589 in BMLS
    *** source: 1846706-Fig-3c

=====================
Auto Kinase Activity
=====================

  *** HgfR[Ab]IP IVKA(auto)[pYAb] is detectable
    *** cells: GTL16 in BMS
    *** source: 2005882-Fig-2a
  *** HgfR[Ab]IP IVKA(auto)[32P-ATP] is increased irt Hgf (times)
    *** cells: A431 in BMLS
    *** times: 0 5+ 10+ 60+ 180+ min
    *** source: 10970810-Fig-1d

===========================
Phosphorylation on Tyrosine
===========================

  *** HgfR[Ab] Yphos[pYAb-ppt] is increased irt Hgf (10 min)
    *** cells: B5589 in BMLS
    *** source: 1846706-Fig-2a
  *** HgfR[Ab]IP Yphos[pYAb] is increased irt Hgf (tnr)
    *** cells: A549 in BMLS
    *** source: 7513258-Fig-1a
  *** HgfR[Ab]IP Yphos[pYAb] is increased irt Hgf (15 min)
    *** cells: A549 in BMLS
    *** source: 8387483-Fig-1
  *** HgfR[Ab]IP Yphos[pYAb] is increased irt Hgf (15 min)
    *** cells: GTL16 in BMLS
    *** inhibited by: TMO [cotreatment]
    *** source: 8387483-Fig-4
  *** HgfR[Ab] Yphos[pYAb] is increased irt Hgf (tnr)
    *** cells: MDCK in BMLS
    *** source: 9252406-Fig-1b
  *** HgfR[Ab]IP Yphos[pYAb] is increased irt Hgf (times)
    *** cells: rENCNs in BMLS
    *** times: 0 5+ 10+ min
    *** source: 9681449-Fig-2
  *** HgfR[Ab]IP Yphos[pYAb] is increased irt Hgf (15 min)
    *** cells: HEK293 in BMLS
    *** source: 9748249-Fig-1a
  *** HgfR[Ab]IP Yphos[pYAb] is increased irt Hgf (tnr)
    *** cells: MIMCD3 in BMS
    *** unaffected by: U0126 [pretreatment]
    *** source: 11445578-Fig-4a
  *** HgfR[Ab]IP Yphos[pYAb] is increased irt Hgf (times)
    *** cells: HEK293T in BMS
    *** times: 0 10++ 20++ min
    *** source: 11894096-Fig-S4
  *** HgfR[Ab]IP Yphos[pYAb] is increased irt Hgf (times)
    *** cells: HEK293T in BMS
    *** times: 0 10++ 30++ 60+ 120+ min
    *** comment: decrease at 60-120 min is reversed itpo xEnd3(mnr)"SH3"
    *** comment: decrease at 60-120 min is unaffected itpo xCin85(mnr)"PCC"
    *** comment: decrease at 60-120 min is unaffected itpo xCbl(mnr)"480"
    *** source: 11894096-Fig-3c
  *** HgfR[Ab]IP Yphos[pYAb] is increased irt Hgf (times)
    *** cells: HELA in BMS
    *** times: 0 1++ 5++ 15+ min
    *** source: 11894096-Fig-2b
  *** HgfR[MW] Yphos[pYAb] is increased irt Hgf (5 min)
    *** cells: HEK293 in BMLS
    *** unaffected by: xMuc20 [addition]
    *** source: 15314156-Fig-2a

==============================
Phosphorylation on Y1234/Y1235
==============================

does not require Src--

  *** HgfR[phosAb] phos(Y1234/Y1235)[phosAb] is increased irt Hgf (15 min)
    *** cells: HEK293<xGab1> in BMLS
    *** unaffected by: xSrc [addition]
    *** unaffected by: xSrc(mnr)"KD" [addition]
    *** source: 12941962-Fig-2a
  *** HgfR[phosAb] phos(Y1234/Y1235)[phosAb] is increased irt Hgf (15 min)
    *** cells: MDCK in BMLS
    *** unaffected by: xSrc(mnr)"KD" [addition]
    *** source: 12941962-Fig-2b

  *** HgfR[phosAb] phos(Y1234/Y1235)[phosAb] is increased irt Hgf (times)
    *** cells: hBMECs in BMS
    *** times: 0+ 5++ 15++ 30++ min
    *** source: 17055484-Fig-2
  *** HgfR[phosAb] phos(S1234/S1235)[phosAb] is increased irt Hgf (times)
    *** cells: HELA in BMS
    *** times: 0 5+ 15++ 30++ 60+ min
    *** source: 19109251-Fig-2d

=====================================
Phosphorylation on an unreported site
=====================================

  *** HgfR[phosAb] phos(sitenr)[phosAb] is increased irt Hgf (times)
    *** cells: CHANG in BMLS
    *** times: 0 10+++ 30++ 60+ 120+ 240 360 480 min
    *** source: 19071214-Fig-1b

