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Traf6 ubiquitination
====================

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Traf6 ubiquitination is increased by dimerization
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  *** xTraf6((1-358)/GyrB)[tAb]IP ubiq[UbAb] is increased irt CoumermycinA (tnr)
    *** cells: HEK293 in BMS
    *** source: 11460167-Fig-4d
  *** xTraf6((1-358)/GyrB)[tAb]IP upshift[WBMS] is increased irt CoumermycinA (times)
    *** cells: HEK293 in BMS
    *** times: 0 2 5 10+ 15++ 20+++ 25+++ 60 min
    *** source: 11460167-Fig-4c
  *** xTraf6((1-358)/GyrB)[tAb]IP upshift[WBMS] is increased irt CoumermycinA (tnr)
    *** cells: HEK293 in BMS
    *** source: 11460167-Fig-4d

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Coprecipitations
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*** Btk--

  *** xTraf6[tAb] copptby[WB] xBtk[Ab] is undetectable
    *** cells: HEK293 in BMS
    *** source: 12724322(D)

Ecsit--

  *** Traf6[Ab] copptby[WB] xEcsit[tAb] is detectable
    *** cells: COS in BMS
    *** source: 10465784-Fig-2a
  *** Traf6[Ab] copptby[WB] xEcsit[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 10465784-Fig-2a

Mavs--

  *** xTraf6[tAb] copptby[WB] xMavs[Ab] is detectable
    *** cells: HEK293 in BMS
    *** source: 16125763-Fig-S5a

Mekk3--

  *** xTraf6[tAb] copptby[WB] xMekk3[tAb] is detectable
    *** cells: mEFs in BMS
    *** source: 14661019(D)
  *** xMekk3[tAb] copptby[WB] xTraf6[tAb] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xTraf6(110-522)"T6dR" [substitution]
    *** partially inhibited by: xTraf6(260-522)"T6dRZ" [substitution]
    *** inhibited by: xTraf6(1-288)"T6dCT" [substitution]
    *** inhibited by: xTraf6(1-348)"T6dT" [substitution]
    *** source: 19843958-Fig-6b

Nod1--

  *** xTraf6[tAb] copptby[WB] xNod1[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 10329646(D)
Peli1--

  *** xTraf6[Ab] copptby[WB] xPeli1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12804775-Fig-1

Peli2--

  *** xTraf6[Ab] copptby[WB] xPeli2[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12804775-Fig-1

Peli3--

  *** xTraf6[tAb] copptby[WB] xPeli3[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12874243-Fig-5b

Sqstm1--

  *** xTraf6[tAb] copptby[WB] xSqstm1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 10747026-Fig-5
  *** xTraf6[tAb] copptby[WB] xSqstm1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 10747026-Fig-10

Tab1--

  *** xTraf6[tAb] copptby[WB] xTab1[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 12724322(D)
  *** xTraf6((1-358)/GyrB)[Ab] copptby[WB] xTab1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xTraf6((1-358)/GyrB/C70A) [substitution]
    *** source: 19112497-Fig-1d

Tab2--

  *** xTraf6[tAb] copptby[WB] xTab2[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 14633987-Fig-4a
  *** xTraf6[tAb] copptby[WB] xTab2[tAb] is detectable
    *** cells: HEK293<xIL1R1> in BMS
    *** source: 14633987-Fig-6a
  *** xTraf6[tAb] copptby[WB] xTab2[tAb] is detectable
    *** cells: HEK293 in BMS
    *** source: 10882101(D)
  *** xTraf6((1-358)/GyrB)[Ab] copptby[WB] xTab2[tAb] is detectable
    *** cells: HEK293T in BMS
    *** unaffected by: xTraf6((1-358)/GyrB/C70A) [substitution]
    *** source: 19112497-Fig-1c

Tab3--

  *** xTraf6[tAb] copptby[WB] xTab3[tAb] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: xTab2 [addition]
    *** source: 14633987-Fig-4c

Tak1--

  *** xTraf6[tAb] copptby[WB] xTak1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** source: 19843958-Fig-S4
  *** xTak1[tAb] copptby[WB] xTraf6[tAb] is detectable
    *** cells: HEK293T in BMS
    *** enhanced by: xTraf6(C86A/H87A) [substitution]
    *** source: 19112497-Fig-1b
  *** xTraf6((1-358)/GyrB)[Ab] copptby[WB] xTak1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** enhanced by: xTraf6((1-358)/GyrB/C70A) [substitution]
    *** source: 19112497-Fig-1d
  *** xTraf6((1-358)/GyrB)[Ab] copptby[WB] xTak1[tAb] is detectable
    *** cells: HEK293T in BMS
    *** enhanced by: xTraf6((1-358)/GyrB/C70A) [substitution]
    *** unaffected by: xTraf6((1-358)/GyrB/C70A/mnr)"K32-348R" [substitution]
    *** source: 19112497-Fig-2c

Tank--

  *** xTraf6[tAb] copptby[WB] xTank[tAb] is undetectable
    *** cells: HEK293 in BMS
    *** source: 10759890-Fig-4b

Trif--

  *** xTraf6[tAb] copptby[WB] xTrif[tAb] is detectable
    *** cells: HEK293 in BMS
    *** unaffected by: xTnfaip3 [addition]
    *** source: 15474016-Fig-3a

Tifa--

  *** xTraf6[tAb] snaggedby[WB] Tifa[GST] is detectable
    *** cells: HEK293T in BMS
    *** source: 12566447-Fig-1d
