==============
Kinase Actvity
==============

  *** Mnk1[Ab]IP IVKA(Eif4e)[32P-ATP] is increased irt PMA (30 min)
    *** cells: HEK293 in BMLS
    *** source: 11154262-Fig-5c
  *** xMnk1[GST]IP IVKA(Eif4e)[32P-ATP] is increased irt PMA (tnr)
    *** cells: HEK293T<xMnk1> in BMS
    *** inhibited by: xMnk1(T197A/T202A) [substitution]
    *** source: 9155017-Fig-9
  *** xMnk1[tAb]IP IVKA(Eif4e)[32P-ATP] is increased irt PMA (30 min)
    *** cells: HEK293<xMnk1> in BMLS
    *** source: 12897141-Fig-3f
  *** xMnk1[tAb]IP IVKA(Eif4e)[32P-ATP] is increased irt PMA (times)
    *** cells: HEK293 in BMLS
    *** times: 0 5 15+ 30++ min
    *** source: 11154262-Fig-5a
  *** xMnk1[tAb]IP IVKA(Eif4e)[32P-ATP] is increased irt PMA (times)
    *** cells: HEK293 in BMLS
    *** times: 0 5 15+ 30++ min
    *** source: 11154262-Fig-6a

Chemicals

  *** xMnk1[GST]IP IVKA(Eif4e)[32P-ATP] is increased irt PMA (tnr)
    *** cells: HEK293T<xMnk1> in BMS
    *** inhibited by: PD98059 [pretreatment]
    *** inhibited by: SB203580 [pretreatment]
    *** source: 9155017-Fig-9


===============
Phosphorylation
===============

  *** Mnk1[phosAb] phos(T250/T257)[phosAb] is increased irt PMA (15 min)
    *** cells: mEFs in BMLS
    *** source: 15254222-Fig-3a
  *** xMnk1[tAb]IP phos(T250/T257)[phosAb] is increased irt PMA (30 min)
    *** cells: HEK293<xMnk1> in BMLS
    *** source: 12897141-Fig-3g

