========================
direct dephosphorylation
========================

  *** xSmad1[tAb]IP phos(S206)[phosAb] is decreased by rCtdsp2
    *** cells: none
    *** IPfrom: HEK293 in BMS "treated with Egf for 30 min"
    *** source: 17085434-Fig-4a

================
indirect effects
================

  *** xSmad1[phosAb] phos(S206)[phosAb] is decreased itpo xCtdsp2
    *** cells: HEK293 in BMS
    *** inhibited by: xCtdsp2(D107E)"CIA" [substitution]
    *** source: 17085434-Fig-2a
  *** xSmad1[phosAb] phos(S206)[phosAb] is detectable
    *** cells: HEK293 in BMS "treated with Bmp? for 1 hr"
    *** inhibited by: xCtdsp2 [addition]
    *** source: 17085434-Fig-2b

=========================
S463/S425 is not dephosed
=========================

  *** xSmad1[phosAb] phos(S463/S425)[phosAb] is detectable
    *** cells: HEK293 in BMS "treated with Bmp? for 1 hr"
    *** unaffected by: xCtdsp2 [addition]
    *** source: 17085434-Fig-2b
