mod EGFRULES is inc ALLOPS .

var xout : Soup .
vars clm cli clc nuc : Soup .
var sig : Soup .
var egfrc : Soup .

*** ~/evidence/Egf-Evidence/00EgfEvidence.txt

rl[001.EgfR.irt.Egf]:
  {XOut  | xout Egf                     }
  {EgfRC | egfrc EgfR                   }
  =>
  {XOut  | xout                         }
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) } .
  -----------------------------------------
  *** ~/evidence/Egf-Evidence/EgfR.irt.Egf.001.txt

*** Abl1--

rl[222.Abl1.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) }
  {CLc   | clc   Abl1                   }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) }
  {CLc   | clc   [Abl1 - act]           } .
  -----------------------------------------
  *** ~/evidence/Egf-Evidence/Abl1.irt.Egf.222.txt

*** Akt1--  

rl[227.Akt1.irt.Egf]:
  {EgfRC  | egfrc ([EgfR - Yphos] : Egf) Pi3k [Gab1 - Yphos]
                  Freud1 RalGds  gnai13s:Gnai13S             }
  {CLc    | clc   Sin1 Rictor Akt1                           }
  =>
  {EgfRC  | egfrc ([EgfR - Yphos] : Egf) Pi3k [Gab1 - Yphos] 
                  Freud1 RalGds  gnai13s:Gnai13S             }
  {CLc    | clc   Sin1 Rictor [Akt1 - act]                   } .
  ----------------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Akt1.irt.Egf.227.txt

*** Araf--

rl[815.Araf.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) }
  {CLc   | clc   Araf                   }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) }
  {CLc   | clc    [Araf - act]          } .
  ----------------------------------------------------
  *** ~/evidence/Egf-Evidence/Araf.irt.Egf.815.txt

*** ArhGap5--

rl[1271.ArhGap5.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Src - act] }
  {CLc   | clc    ArhGap5                           }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Src - act] }
  {CLc   | clc   [ArhGap5 - Yphos]                                                     } .
  ----------------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/ArhGap5.irt.Egf.1271.txt

*** ArhGef4--

rl[156.ArhGef4.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Src - act]                   }
  {CLc   | clc    ArhGef4                                             }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Src - act] [ArhGef4 - Yphos] }
  {CLc   | clc                                                        } .
  ----------------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/ArhGef4.irt.Egf.156.txt

*** ArhGef7--

rl[264.ArhGef7.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Src - act]                   }
  {CLc   | clc   Fak1 ArhGef7                                         }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Src - act] [ArhGef7 - Yphos] }
  {CLc   | clc   Fak1                                                 } .
  ---------------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/ArhGef7.irt.Egf.264.txt

*** Atf1--

rl[628.Atf1.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)                     }
  {NUc   | nuc    [msk12s:Msk12S - act] Atf1                }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)                     }
  {NUc   | nuc    [msk12s:Msk12S - act] [Atf1 - phos(S 63)] } .
  --------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Atf1.irt.Egf.628.txt

*** Atf2--

rl[352.Atf2.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) }
  {CLc   | clc   [Jnks - act] Atf2      }
  {NUc   | nuc                          }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) }
  {CLc   | clc   [Jnks - act]           }
  {NUc   | nuc   [Atf2 - phos]          } .
  -----------------------------------------
  *** ~/evidence/Egf-Evidence/Atf2.irt.Egf.352.txt

*** Bmx--

rl[263.Bmx.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)               }
  {CLc   | clc   Bmx                                  }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Bmx - Yphos] }
  {CLc   | clc                                        } .
  -------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Bmx.irt.Egf.263.txt

*** Braf--

rl[310.Braf.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)           }
  {CLi   | cli    [Hras - GTP]                    }
  {CLc   | clc   IqGap1 [Mlk3 - act]  Braf        }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)           }
  {CLi   | cli    [Hras - GTP]                    }
  {CLc   | clc   IqGap1 [Mlk3 - act] [Braf - act] } .
  ---------------------------------------------------
  *** ~/evidence/Egf-Evidence/Braf.irt.Egf.310.txt

*** Cbl--

rl[096.Cbl.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)               }
  {CLc   | clc   Cbl                                  }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Cbl - Yphos] }
  {CLc   | clc                                        } .
  -------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Cbl.irt.Egf.096.txt

*** Cblb--

rl[353.Cblb.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)                }
  {CLc   | clc   Cblb                                  }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Cblb - Yphos] }
  {CLc   | clc                                         } .
  --------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Cblb.irt.Egf.353.txt

*** Cdc42--

rl[399.Cdc42.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Src - act] 
                  [cdc42gef:Cdc42GEF - Yphos]         }
  {CLi   | cli    [Cdc42 - GDP]                       }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Src - act] 
                  [cdc42gef:Cdc42GEF - Yphos]         }
  {CLi   | cli    [Cdc42 - GTP]                       } .
  -------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Cdc42.irt.Egf.399.txt

*** Cin85--

rl[550.Cin85.irt.Egf.Cbl]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Cbl - Yphos]       }
  {CLc   | clc   Cin85                                      }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Cbl - Yphos] Cin85 }
  {CLc   | clc                                              } .
  -----------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Cin85.irt.Egf.Cbl.550.txt

rl[579.Cin85.irt.Egf.Cblb]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Cblb - Yphos]       }
  {CLc   | clc     Cin85                                     }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Cblb - Yphos] Cin85 }
  {CLc   | clc                                               } .
  ------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Cin85.irt.Egf.Cblb.579.txt

*** Creb1--

rl[403.Creb1.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [mek12s:Mek12S - act] }
  {NUc   | nuc   [msk12s:Msk12S - act] Creb1                  }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [mek12s:Mek12S - act] }
  {NUc   | nuc   [msk12s:Msk12S - act] [Creb1 - phos(S 133)]  } .
  ---------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Creb1.irt.Egf.403.txt

*** Crk--

rl[102.Crk.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)               }
  {CLc   | clc   Crk                                  }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Crk - Yphos] }
  {CLc   | clc                                        } .
  -------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Crk.irt.Egf.102.txt

*** CrkL--

rl[115.CrkL.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)                }
  {CLc   | clc   CrkL                                  }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [CrkL - Yphos] }
  {CLc   | clc                                         } .
  ------------------------------------------------------
  *** ~/evidence/Egf-Evidence/CrkL.irt.Egf.115.txt

*** Csk--

rl[474.Csk.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)  [Pag1 - Yphos]     }
  {CLc   | clc   Csk                                        }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)  [Pag1 - Yphos] Csk }
  {CLc   | clc                                              } .
  -----------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Csk.irt.Egf.474.txt

*** Dbl--

rl[389.Dbl.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)               }
  {CLc   | clc   Dbl                                  }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Dbl - Yphos] }
  {CLc   | clc                                        } .
  -------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Dbl.irt.Egf.389.txt

*** Dok1--

rl[486.Dok1.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Shp2 - Yphos]                }
  {CLc   | clc   Dok1                                                 }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Shp2 - Yphos] [Dok1 - Yphos] }
  {CLc   | clc                                                        } .
  -----------------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Dok1.irt.Egf.486.txt

*** Dok2--

rl[103.Dok2.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)                 }
  {CLc   | clc   Dok2                                   }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)  [Dok2 - Yphos] }
  {CLc   | clc                                          } .
  -------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Dok2.irt.Egf.103.txt

*** EgfR--

rl[828.EgfR.ubiq.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Cbl - Yphos] [Src - act]  }
  {CLc   | clc   Ube2l3                                            }
  =>
  {EgfRC | egfrc ([EgfR - ubiq] : Egf)  [Cbl - Yphos] [Src - act] }
  {CLc   | clc   Ube2l3                                           } .
  -------------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/EgfR.ubiq.irt.Egf.828.txt

***(
rl[580.EgfR.Internalized]:
  {EgfRC | egfrc ([EgfR - ubiq] : Egf)  [cbls:CblS - Yphos] 
                 Cin85 [Tnk2 - Yphos]                         }
  {EEm   | eem                                                }
  =>
  {EgfRC | egfrc                                              }
  {EEm   | eem   ([EgfR - ubiq] : Egf) [Tnk2 - Yphos]
                 [cbls:CblS - Yphos] Cin85                    } .
  ---------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/EgfR.Internalized.580.txt

rl[585.EgfR.Degraded]:
  {CLi   | cli    [Rala - GTP]                                        }
  {EEm | eem ([EgfR - ubiq] : Egf) [Tnk2 - Yphos] [cbls:CblS - Yphos] }
  {Sig | sig                                                          }
  =>
  {CLi   | cli    [Rala - GTP]                                        }
  {EEm | eem  [Tnk2 - Yphos]  [cbls:CblS - Yphos]                     }
  {Sig | sig  [EgfR - degraded] [Egf - degraded]                      } .
  -----------------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/EgfR.Degraded.585.txt
)***

*** Egr1--  Egr1-gene--

rl[620.Egr1-gene.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)  }
  {NUc   | nuc   Egr1-gene               }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)  }
  {NUc   | nuc   [Egr1-gene - on]        } .
  -------------------------------------------
  *** ~/evidence/Egf-Evidence/Egr1-gene.irt.Egf.620.txt

*** Eif4ebp1--

rl[016.Eif4ebp1.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) gnai13s:Gnai13S }
  {CLc   | clc   Eif4ebp1                               }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) gnai13s:Gnai13S }
  {CLc   | clc   [Eif4ebp1 - phos(S 65)]                } .
  -----------------------------------------------------------
  *** ~/evidence/Ins-Evidence/Eif4ebp1.irt.Egf.016.txt

*** Elk1--

rl[946.Elk1.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)      }
  {CLi   | cli    [Hras - GTP]               }
  {NUc   | nuc    [Erks - act] Elk1          }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)      }
  {CLi   | cli    [Hras - GTP]               }
  {NUc   | nuc    [Erks - act] [Elk1 - act]  } .
  -----------------------------------------------
  *** ~/evidence/Egf-Evidence/Elk1.irt.Egf.946.txt

*** EndA1--

rl[546.EndA1.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)       }
  {CLc   | clc   EndA1                        }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) EndA1 }
  {CLc   | clc                                } .
  ------------------------------------------------
  *** ~/evidence/Egf-Evidence/EndA1.irt.Egf.546.txt

*** Eps8--

rl[112.Eps8.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)                }
  {CLc   | clc   Eps8                                  }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Eps8 - Yphos] }
  {CLc   | clc                                         } .
  --------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Eps8.irt.Egf.112.txt

*** Eps15--

rl[1100.Eps15.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) }
  {CLc   | clc   Eps15                  }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) }
  {CLc   | clc    [Eps15 - Yphos]       } .
  -----------------------------------------
  *** ~/evidence/Egf-Evidence/Eps15.irt.Egf.1100.txt

*** Erbb2--

rl[113.Erbb2.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)                 }
  {CLm   | clm   Erbb2                                  }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Erbb2 - Yphos] }
  {CLm   | clm                                          } .
  ---------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Erbb2.irt.Egf.113.txt

*** ErkS--

rl[196.Erks.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)  [Fak2 - act] [gab:GabS - Yphos]
                  [Git1 - Yphos] Pi3k [Shp2 - Yphos] [Shc1 - Yphos] [Src - act]   }
  {CLi   | cli   [Hras - GTP] plds:PldS                                           }
  {CLc   | clc   [Braf - act] IqGap1 [Mek1 - act] [Mlk3 - act] Shoc2 Erks         }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Fak2 - act] [gab:GabS - Yphos]
                  [Git1 - Yphos] Pi3k [Shp2 - Yphos] [Shc1 - Yphos] [Src - act]   }
  {CLi   | cli   [Hras - GTP] plds:PldS                                           }
  {CLc   | clc   [Braf - act] IqGap1 [Mek1 - act] [Mlk3 - act] Shoc2 [Erks - act] } .
  -----------------------------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Erks.irt.Egf.196.txt

rl[1602.Erks.to.nuc.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)         }
  {CLc   | clc   [Erks - act]                   }
  {NUc   | nuc                                  }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)         }
  {CLc   | clc                                  }
  {NUc   | nuc   [Erks - act]                   } .
  ---------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Erks.to.nuc.irt.Egf.1602.txt

*** Erk5--

rl[028.Erk5.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)                             }
  {CLi   | cli    [Hras - GTP]                                      }
  {CLc   | clc    [Mek5 - act]  [mekk23:Mekk23S - act]Erk5          }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)                             }
  {CLi   | cli    [Hras - GTP]                                      }
  {CLc   | clc    [Mek5 - act]  [mekk23:Mekk23S - act] [Erk5 - act] } .
  ---------------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Erk5.irt.Egf.028.txt

*** Fak2--

rl[186.Fak2.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Src - act]              }
  {CLc   | clc   Fak2                                            }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Src - act] [Fak2 - act] }
  {CLc   | clc                                                   } .
  ------------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Fak2.irt.Egf.186.txt

*** Flna--

rl[1274.Flna.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)          }
  {CLc   | clc   [rsks:RskS - act] Flna          }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)          }
  {CLc   | clc   [rsks:RskS - act] [Flna - phos] } .
  --------------------------------------------------
  *** ~/evidence/Egf-Evidence/Flna.irt.Egf.1274.txt

*** Fos--

rl[246.Fos.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)           }
  {NUc   | nuc   [Erks - act] Fos                 }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)           }
  {NUc   | nuc   [Erks - act] [Fos - phos(T 325)] } .
  ----------------------------------------------------
  *** ~/evidence/Egf-Evidence/Fos.irt.Egf.246.txt

*** Fos-gene--

rl[631.Fos-gene.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)  }
  {CLc   | clc   [mek12s:Mek12S - act]   }
  {NUc   | nuc   Fos-gene                }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)  }
  {CLc   | clc   [mek12s:Mek12S - act]   }
  {NUc   | nuc   [Fos-gene - on]         } .
  ------------------------------------------
  *** ~/evidence/Egf-Evidence/Fos-gene.irt.Egf.631.txt

*** Gab1--

rl[116.Gab1.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) gnai13s:Gnai13S                }
  {CLc   | clc   Gab1                                                  }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) gnai13s:Gnai13S [Gab1 - Yphos] }
  {CLc   | clc                                                         } .
  ------------------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Gab1.irt.Egf.116.txt

*** Gab2--

rl[075.Gab2.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)                }
  {CLc   | clc   Gab2                                  }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Gab2 - Yphos] }
  {CLc   | clc                                         } .
  --------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Gab2.irt.Egf.075.txt

*** Git1--

rl[398.Git1.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Src - act]                }
  {CLc   | clc   Git1                                              }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Src - act] [Git1 - Yphos] }
  {CLc   | clc                                                     } .
  ---------------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Git1.irt.Egf.398.txt

*** Gnai1--

rl[012.Gnai1.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)       }
  {CLi   | cli   Gnai1                        }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) Gnai1 }
  {CLi   | cli                                } .
  -----------------------------------------------
  *** ~/evidence/Egf-Evidence/Gnai1.irt.Egf.012.txt

*** Gnai3--

rl[013.Gnai3.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)       }
  {CLi   | cli   Gnai3                        }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) Gnai3 }
  {CLi   | cli                                } .
  -----------------------------------------------
  *** ~/evidence/Egf-Evidence/Gnai3.irt.Egf.013.txt

*** Grb2--

rl[117.Grb2.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)      }
  {CLc   | clc   Grb2                        }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) Grb2 }
  {CLc   | clc                               } .
  -----------------------------------------------
  *** ~/evidence/Egf-Evidence/Grb2.irt.Egf.117.txt

*** Gsk3s--

rl[1601.Gsk3s.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) }
  {CLc   | clc   [Gsk3s - act]          }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) }
  {CLc   | clc   [Gsk3s - phos(SFAE)]   } .
  -----------------------------------------------
  *** ~/evidence/Egf-Evidence/Gsk3s.irt.Egf.1601.txt

*** HistH3--

rl[1057.HistH3.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) }
  {NUc   | nuc   HistH3                 }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) }
  {NUc   | nuc   [HistH3 - phos(S 11)]  } .
  -----------------------------------------------
  *** ~/evidence/Egf-Evidence/HistH3.irt.Egf.1057.txt

*** Hpk1--

rl[218.Hpk1.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [crks:CrkS - Yphos]              }
  {CLc   | clc   Hpk1                                                    }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [crks:CrkS - Yphos] [Hpk1 - act] }
  {CLc   | clc                                                           } .
  --------------------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Hpk1.irt.Egf.218.txt

*** Hras--

rl[529.Hras.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [gab:GabS - Yphos]
                  [hrasgef:HrasGEF - Yphos] Pi3k [Shp2 - Yphos] }
  {CLi   |  cli   [Hras - GDP]                                  }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [gab:GabS - Yphos]
                  [hrasgef:HrasGEF - Yphos] Pi3k [Shp2 - Yphos] }
  {CLi   | cli    [Hras - GTP]                                  } .
  ---------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Hras.irt.Egf.529.txt

*** Irf1--

rl[760.Irf1-gene.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)  }
  {NUc   | nuc   Irf1-gene               }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)  }
  {NUc   | nuc   [Irf1-gene - on]        } .
  -------------------------------------------
  *** ~/evidence/Egf-Evidence/Irf1-gene.irt.Egf.760.txt

*** Jak1--

rl[913.Jak1.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)                }
  {CLc   | clc   Jak1                                  }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Jak1 - Yphos] }
  {CLc   | clc                                         } .
  --------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Jak1.irt.Egf.913.txt

*** Jak2--

rl[126.Jak2.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)                }
  {CLc   | clc   Jak2                                  }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Jak2 - Yphos] }
  {CLc   | clc                                         } .
  --------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Jak2.irt.Egf.126.txt

*** JnkS--

rl[678.JnkS.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Eps8 - Yphos] }
  {CLi   | cli    [Cdc42 - GTP]                        }
  {CLc   | clc    [Mlk3 - act] Jnks                    }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Eps8 - Yphos] }
  {CLi   | cli    [Cdc42 - GTP]                        }
  {CLc   | clc    [Mlk3 - act] [Jnks - act]            } .
  --------------------------------------------------------
  *** ~/evidence/Egf-Evidence/JnkS.irt.Egf.678.txt

*** Jun--

rl[627.Jun.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)  }
  {CLi   | cli    [Hras - GTP]           }
  {NUc   | nuc     Jun                   }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)  }
  {CLi   | cli    [Hras - GTP]           }
  {NUc   | nuc    [Jun - phos]           } .
  ------------------------------------------
  *** ~/evidence/Egf-Evidence/Jun.irt.Egf.627.txt

*** Jun-gene--

rl[664.Jun-gene.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)  }
  {CLc   | clc     [mek12s:Mek12S - act] }
  {NUc   | nuc      Jun-gene             }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)  }
  {CLc   | clc    [mek12s:Mek12S - act]  }
  {NUc   | nuc    [Jun-gene - on]        } .
  ------------------------------------------
  *** ~/evidence/Egf-Evidence/Jun-gene.irt.Egf.664.txt

*** Junb--  Junb-gene--

rl[661.Junb-gene.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)  }
  {NUc   | nuc   Junb-gene               }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)  }
  {NUc   | nuc   [Junb-gene - on]        } .
  -------------------------------------------
  *** ~/evidence/Egf-Evidence/Junb-gene.irt.Egf.661.txt

*** Kras--

rl[161.Kras.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) krasgef:KrasGEF }
  {CLi   | cli   [Kras - GDP]                           }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) krasgef:KrasGEF }
  {CLi   | cli    [Kras - GTP]                          } .
  ---------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Kras.irt.Egf.161.txt

*** Lkb1--

rl[530.Lkb1.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Mek1 - act]                      }
  {CLc   | clc   Lkb1                                                     }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Mek1 - act] [Lkb1 - phos(S 431)] }
  {CLc   | clc                                                            } .
  ---------------------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Lkb1.irt.Egf.530.txt

*** Mapkapk2--

rl[662.Mapkapk2.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)        }
  {CLc   | clc   [P38s - act]  Mapkapk2        }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)        }
  {CLc   | clc   [P38s - act] [Mapkapk2 - act] } .
  -----------------------------------------------
  *** ~/evidence/Egf-Evidence/Mapkapk2.irt.Egf.662.txt

*** Mek1--

rl[639.Mek1.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [gab:GabS - Yphos] }
  {CLc   | clc   [Mlk3 - act] [Braf - act]  Mek1           }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [gab:GabS - Yphos] }
  {CLc   | clc   [Mlk3 - act] [Braf - act] [Mek1 - act]    } .
  -------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Mek1.irt.Egf.639.txt

*** Mek5--

rl[570.Mek5.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) }
  {CLc   | clc   Mek5                   }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) }
  {CLc   | clc   [Mek5 - act]           } .
  ------------------------------------------
  *** ~/evidence/Egf-Evidence/Mek5.irt.Egf.570.txt

*** Mekk1--

rl[480.Mekk1.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) }
  {CLc   | clc   Mekk1                  }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) }
  {CLc   | clc    [Mekk1 - act]         } .
  -----------------------------------------
  *** ~/evidence/Egf-Evidence/Mekk1.irt.Egf.480.txt

*** Mekk2--

rl[1106.Mekk2.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) }
  {CLc   | clc   Mekk2                  }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) }
  {CLc   | clc    [Mekk2 - act]         } .
  -------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Mekk2.irt.Egf.1106.txt

*** Mekk3--

rl[217.Mekk3.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)               }
  {CLc   | clc   Mekk3                                }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Mekk3 - act] }
  {CLc   | clc                                        } .
  -------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Mekk3.irt.Egf.217.txt

*** Mlk3--

rl[1063.Mlk3.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)              }
  {CLi   | cli    [cdc42rac1s:Cdc42Rac1S - GTP]      }
  {CLc   | clc     Mlk3                              }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) }
  {CLi   | cli    [cdc42rac1s:Cdc42Rac1S - GTP]      }
  {CLc   | clc    [Mlk3 - act]                       } .
  ------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Mlk3.irt.Egf.1063.txt

*** Mras--

rl[334.Mras.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)  }
  {CLi   | cli   [Mras - GDP]            }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)  }
  {CLi   | cli    [Mras - GTP]           } .
  -------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Mras.irt.Egf.334.txt

*** Msk1--

rl[166.Msk1.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)      }
  {CLc   | clc    [Mek1 - act] [P38s - act]  }
  {NUc   | nuc     Msk1                      }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)      }
  {CLc   | clc    [Mek1 - act] [P38s - act]  }
  {NUc   | nuc    [Msk1 - act]               } .
  -------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Msk1.irt.Egf.166.txt

*** Msk2--

rl[763.Msk2.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)               }
  {CLc   | clc    [Mek1 - act] [P38s - act]           }
  {NUc   | nuc     Msk2                               }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)  [Mek1 - act] }
  {CLc   | clc    [Mek1 - act] [P38s - act]           }
  {NUc   | nuc    [Msk2 - act]                        } .
  -------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Msk2.irt.Egf.763.txt

*** Myc--  

rl[808.Myc.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)          }
  {NUc   | nuc   Myc                             }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)          }
  {NUc   | nuc   [Myc - phos(S 62)]              } .
  --------------------------------------------------
  *** ~/evidence/Egf-Evidence/Myc.irt.Egf.808.txt

*** Myc-gene--

rl[668.Myc-gene.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)  [Shc1 - Yphos] }
  {NUc   | nuc     Myc-gene                             }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)  [Shc1 - Yphos] }
  {NUc   | nuc    [Myc-gene - on]                       } .
  ----------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Myc-gene.irt.Egf.668.txt

*** Nckipsd--

rl[1272.Nckipsd.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Src - act] }
  {CLc   | clc    Nckipsd                           }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Src - act] }
  {CLc   | clc   [Nckipsd - Yphos]                                                     } .
  ----------------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Nckipsd.irt.Egf.1272.txt

*** Nos2a--  Nos2a-gene--

rl[173.Nos2a-gene.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)          }
  {NUc   | nuc   [Stat3 - act] Nos2a-gene        }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)          }
  {NUc   | nuc   [Stat3 - act] [Nos2a-gene - on] } .
  ----------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Nos2a-gene.irt.Egf.173.txt

*** Nras--

rl[165.Nras.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) nrasgef:NrasGEF  }
  {CLi   | cli    [Nras - GDP]                           }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) nrasgef:NrasGEF  }
  {CLi   | cli    [Nras - GTP]                           } .
  ----------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Nras.irt.Egf.165.txt

*** P38s--

rl[940.P38s.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) }
  {CLc   | clc     P38s                 }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) }
  {CLc   | clc    [P38s - act]          } .
  -----------------------------------------
  *** ~/evidence/Egf-Evidence/P38s.irt.Egf.940.txt

*** Pag1--

rl[147.Pag1.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)                }
  {CLm   | clm   Pag1                                  }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Pag1 - Yphos] }
  {CLm   | clm                                         } .
  ---------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Pag1.irt.Egf.147.txt

*** Pak1--

rl[937.Pak1.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)          }
  {CLi   | cli    [cdc42rac1s:Cdc42Rac1S - GTP]  }
  {CLc   | clc     Pak1                          }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)          }
  {CLi   | cli    [cdc42rac1s:Cdc42Rac1S - GTP]  }
  {CLc   | clc    [Pak1 - act]                   } .
  --------------------------------------------------
  *** ~/evidence/Egf-Evidence/Pak1.irt.Egf.937.txt

*** Pdpk1-- Freud1--

rl[1079.Pdpk1.Freud1.to.EgfR]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) Pi3k                      }
  {CLc   | clc     Freud1  Pdpk1                                  } 
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) Pi3k Freud1 [Pdpk1 - act] }
  {CLc   | clc                                                    } .
  -------------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Pdpk1.Freud1.to.EgfR.1079.txt

*** Pi3k--

rl[172.Pi3k.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)      }
  {CLc   | clc     Pi3k                      }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) Pi3k }
  {CLc   | clc                               } .
  ----------------------------------------------
  *** ~/evidence/Egf-Evidence/Pi3k.irt.Egf.172.txt

*** Pkcd--

rl[724.Pkcd.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)            }
  {CLc   | clc     Pkcd                            }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)            }
  {CLc   | clc    [Pkcd - phos(T 507) phos(S 645)] } .
  --------------------------------------------------
  *** ~/evidence/Egf-Evidence/Pkcd.irt.Egf.724.txt

*** Pkcz--

rl[002.Pkcz.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) Pi3k }
  {CLc   | clc     Pkcz                      }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) Pi3k }
  {CLc   | clc    [Pkcz - act]               } .
  -----------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Pkcz.irt.Egf.002.txt

*** Plce1--

rl[311.Plce1.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Rap2b - GTP]       }
  {CLc   | clc     Plce1                                    }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Rap2b - GTP] Plce1 }
  {CLc   | clc                                              } .
  ------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Plce1.irt.Egf.311.txt

*** Plcg1--

rl[176.Plcg1.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Shp2 - Yphos] [Src - act]   }
  {CLc   | clc     Plcg1                                             }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Shp2 - Yphos] [Src - act]
                  [Plcg1 - phos(Y 783)]                              }
  {CLc   | clc                                                       } .
  ------------------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Plcg1.irt.Egf.176.txt

*** Plscr1--

rl[184.Plscr1.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)                   }
  {CLm   | clm   Plscr1                                   }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)  [Plscr1 - Yphos] }
  {CLm   | clm                                            } .
  -----------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Plscr1.irt.Egf.184.txt

*** Ptk6--

rl[532.Ptk6.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)              }
  {CLc   | clc     Ptk6                              }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Ptk6 - act] }
  {CLc   | clc                                       } .
  ------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Ptk6.irt.Egf.532.txt

*** Shp2--

rl[188.Shp2.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)                 }
  {CLc   | clc   Shp2                                   }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)  [Shp2 - Yphos] }
  {CLc   | clc                                          } .
  ---------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Shp2.irt.Egf.188.txt

*** Pxn--

rl[1102.Pxn.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)               }
  {CLc   | clc    [Ptk6 - act] Pxn                    }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Pxn - Yphos] }
  {CLc   | clc    [Ptk6 - act]                        } .
  --------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Pxn.irt.Egf.1102.txt

*** Rac1--

rl[683.Rac1.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Pxn - Yphos] 
                  [rac1gef:Rac1GEF - Yphos]             }
  {CLi   | cli    [Rac1 - GDP]                          }
  {CLc   | clc    [Ptk6 - act]                          }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Pxn - Yphos] 
                  [rac1gef:Rac1GEF - Yphos]             }
  {CLi   | cli    [Rac1 - GTP]                          }
  {CLc   | clc    [Ptk6 - act]                          } .  
  ----------------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Rac1.irt.Egf.683.txt

*** Raf1--

rl[378.Raf1.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Gab1 - Yphos] }
  {CLi   | cli   [Hras - GTP]                          }
  {CLc   | clc   [Braf - act] Raf1                     }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Gab1 - Yphos] }
  {CLi   | cli   [Hras - GTP]                          }
  {CLc   | clc   [Braf - act]  [Raf1 - act]            } .
  -------------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Raf1.irt.Egf.378.txt

*** Rala--

rl[1064.Rala.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) ralagef:RalaGEF }
  {CLi   | cli    [Rala - GDP]                          }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) ralagef:RalaGEF }
  {CLi   | cli    [Rala - GTP]                          } .
  --------------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Rala.irt.Egf.1064.txt

*** Ralb--

rl[1107.Ralb.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)         }
  {CLi   | cli     ralbgef:RalbGEF [Ralb - GDP] }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)         }
  {CLi   | cli     ralbgef:RalbGEF [Rala - GTP] } .
  -------------------------------------------------
  *** ~/evidence/Egf-Evidence/Ralb.irt.Egf.1107.txt

*** RalGds--

rl[1085.RalGds.to.EgfR]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)                }
  {CLi   | cli    [ralgdspull:RalGdsPull - GTP]        }
  {CLc   | clc   RalGds                                }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)                }
  {CLi   | cli    [ralgdspull:RalGdsPull - GTP] RalGds }
  {CLc   | clc                                         } .
  --------------------------------------------------------
  *** ~/evidence/Egf-Evidence/RalGds.to.EgfR.1085.txt
  *** requirement for a RalGdsPull from common rules

*** Rap1a--

rl[369.Rap1a.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Cbl - Yphos]
                  [rap1agef:Rap1aGEF - Yphos]              }
  {CLi   | cli    [Rap1a - GDP]                            }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Cbl - Yphos] 
                  [rap1agef:Rap1aGEF - Yphos]              }
  {CLi   | cli    [Rap1a - GTP]                            } .
  ------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Rap1a.irt.Egf.369.txt

*** Rap2b--

rl[365.Rap2b.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Src - act]  }
  {CLi   | cli    [Rap2b - GDP]                      }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Src - act]  }
  {CLi   | cli    [Rap2b - GTP]                      } .
  ------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Rap2b.irt.Egf.365.txt

*** RapGef1--

rl[452.RapGef1.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Crk - Yphos]  [Src - act]     }
  {CLc   | clc     RapGef1                                             }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Crk - Yphos]  [Src - act]
                  [RapGef1 - Yphos]                                    }
  {CLc   | clc                                                         } .
  ------------------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/RapGef1.irt.Egf.452.txt

*** Rasa1--

rl[537.Rasa1.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)                  }
  {CLc   | clc     Rasa1                                 }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)  [Rasa1 - Yphos] }
  {CLc   | clc                                           } .
  ----------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Rasa1.irt.Egf.537.txt

*** RasGrp3--

rl[440.RasGrp3.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Src - act]                   }
  {CLc   | clc   RasGrp3                                              }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Src - act] [RasGrp3 - Yphos] }
  {CLc   | clc                                                        } .
  ---------------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/RasGrp3.irt.Egf.440.txt

*** Rela--

rl[727.Rela.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) }
  {CLc   | clc    Rela                  }
  {NUc   | nuc                          }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) }
  {CLc   | clc                          }
  {NUc   | nuc   [Rela - act]           } .
  -----------------------------------------
  *** ~/evidence/Egf-Evidence/Rela.irt.Egf.727.txt

*** Rps6--

rl[1600.Rps6.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) gnai13s:Gnai13S                }
  {CLc   | clc   Rps6                                                  }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) gnai13s:Gnai13S                }
  {CLc   | clc   [Rps6 - phos(S 235)phos(S 236)phos(S 240)phos(S 244)] } .
  ------------------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Rps6.irt.Egf.1600.txt

*** Rin1--

rl[1570.Rin1.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) }
  {CLc   | clc    Rin1                  }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) }
  {CLc   | clc    Rin1                  } .
  -----------------------------------------
  *** ~/evidence/Egf-Evidence/Rin1.irt.Egf.1570.txt


*** Rit1--

rl[281.Rit1.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) }
  {CLi   | cli    [Rit1 - GDP]          }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) }
  {CLi   | cli    [Rit1 - GTP]          } .
  -----------------------------------------
  *** ~/evidence/Egf-Evidence/Rit1.irt.Egf.281.txt

*** Rsk1--

rl[1108.Rsk1.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)                  }
  {CLc   | clc   [Erks - act] [Mek1 - act]  Rsk1         }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)                  }
  {CLc   | clc   [Erks - act] [Mek1 - act] [Rsk1 - act]  } .
  --------------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Rsk1.irt.Egf.1108.txt
  *** ~/evidence/Egf-Evidence/Rsks.irt.Egf.txt

*** Rsk2--

rl[1267.Rsk2.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)      }
  {CLc   | clc    [Mek1 - act]   Rsk2        }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)      }
  {CLc   | clc    [Mek1 - act]  [Rsk2 - act] } .
  ----------------------------------------------
  *** ~/evidence/Egf-Evidence/Rsk2.irt.Egf.1267.txt

*** Rsk3--

rl[663.Rsk3.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)     }
  {CLc   | clc    [Mek1 - act] Rsk3         }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)     }
  {CLc   | clc    [Mek1 - act] [Rsk3 - act] } .
  ---------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Rsk3.irt.Egf.663.txt

*** S6k1--

rl[1111.S6k1.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) Pi3k gnai13s:Gnai13S  }
  {CLi   | cli   [Cdc42 - GTP]                                }
  {CLc   | clc   (Mlst8 : Mtor : Raptor) S6k1                 }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)  Pi3k gnai13s:Gnai13S }
  {CLi   | cli   [Cdc42 - GTP]                                }
  {CLc   | clc   (Mlst8 : Mtor : Raptor) [S6k1 - act]         } .
  ----------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/S6k1.irt.Egf.1111.txt

*** Sh2d3a--

rl[454.Sh2d3a.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)                  }
  {CLc   | clc   Sh2d3a                                  }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Sh2d3a - Yphos] }
  {CLc   | clc                                           } .
  ----------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Sh2d3a.irt.Egf.454.txt

*** Sh2d3c--

rl[545.Sh2d3c.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)                  }
  {CLc   | clc   Sh2d3c                                  }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Sh2d3c - Yphos] }
  {CLc   | clc                                           } .
  ----------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Sh2d3c.irt.Egf.545.txt

*** Shc1--

rl[191.Shc1.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)                }
  {CLc   | clc   Shc1                                  }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Shc1 - Yphos] }
  {CLc   | clc                                         } .
  ------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Shc1.irt.Egf.191.txt

*** Smad3--

rl[906.Smad3.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)        }
  {CLc   | clc    [Erks - act] Smad3           }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)        }
  {CLc   | clc    [Erks - act] [Smad3 - phos]  } .
  ---------------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Smad3.irt.Egf.906.txt

*** Socs3-- Socs3-gene--

rl[1075.Socs3-gene.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)  }
  {NUc   | nuc   Socs3-gene              }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)  }
  {NUc   | nuc   [Socs3-gene - on]       } .
  -------------------------------------------
  *** ~/evidence/Egf-Evidence/Socs3-gene.irt.Egf.1075.txt

*** Sos1--

rl[197.Sos1.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) Grb2                }
  {CLc   | clc   Sos1                                       }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) Grb2 [Sos1 - Yphos] }
  {CLc   | clc                                              } .
  -------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Sos1.irt.Egf.197.txt

*** Src--

rl[207.Src.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Shp2 - Yphos]             }
  {CLi   | cli   Src                                               }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Shp2 - Yphos] [Src - act] }
  {CLi   | cli                                                     } .
  ---------------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Src.irt.Egf.207.txt

*** Stat1--

rl[235.Stat1.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)                 }
  {CLc   | clc   Stat1                                  }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Stat1 - Yphos] }
  {CLc   | clc                                          } .
  ---------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Stat1.irt.Egf.235.txt


rl[964.Stat1.to.nuc.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Stat1 - Yphos] }
  {NUc   | nuc                                          }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)                 }
  {NUc   | nuc   [Stat1 - Yphos]                        } .
  ---------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Stat1.to.nuc.irt.Egf.964.txt

*** Stat3--

rl[241.Stat3.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Src - act] [Fak2 - act]  }
  {CLc   | clc   [Mekk1 - act] Stat3                              }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Src - act] [Fak2 - act]
                  [Stat3 - Yphos]                                 }
  {CLc   | clc    [Mekk1 - act]                                   } .
  -------------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Stat3.irt.Egf.241.txt

rl[963.Stat3.to.nuc.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Stat3 - Yphos]   }
  {NUc   | nuc                                            }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)                   }
  {NUc   | nuc   [Stat3 - act]                            } .
  ---------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Stat3.to.nuc.irt.Egf.963.txt

*** Stat5a--

rl[253.Stat5a.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)                  }
  {CLc   | clc   Stat5a                                  }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Stat5a - Yphos] }
  {CLc   | clc                                           } .
  ----------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Stat5a.irt.Egf.253.txt


rl[948.Stat5a.to.nuc.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Stat5a - Yphos] }
  {NUc   | nuc                                           }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)                  }
  {NUc   | nuc   [Stat5a - Yphos]                        } .
  ----------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Stat5a.to.nuc.irt.Egf.948.txt

*** Stat5b--

rl[907.Stat5b.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)                  }
  {CLc   | clc   Stat5b                                  }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Stat5b - Yphos] }
  {CLc   | clc                                           } .
  ----------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Stat5b.irt.Egf.907.txt


rl[947.Stat5b.to.nuc.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Stat5b - Yphos] }
  {NUc   | nuc                                           }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)                  }
  {NUc   | nuc   [Stat5b - Yphos]                        } .
  ----------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Stat5b.to.nuc.irt.Egf.947.txt

*** Tbp--  Tbp-gene--

rl[1547.Tbp-gene.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Stat5b - Yphos] }
  {CLc   | clc    [Jnks - act]                           }
  {NUc   | nuc    [Elk1 - act] Tbp-gene                  }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Stat5b - Yphos] }
  {CLc   | clc    [Jnks - act]                           }
  {NUc   | nuc    [Elk1 - act] Tbp-gene                  } .
  ----------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Tbp-gene.irt.Egf.1547.txt

*** Tnk2--

rl[254.Tnk2.irt.Egf]:
  {EgfRC | egfrc ([EgfR - ubiq] : Egf)                 }
  {CLc   | clc   Tnk2                                  }
  =>
  {EgfRC | egfrc ([EgfR - ubiq] : Egf)  [Tnk2 - Yphos] }
  {CLc   | clc                                         } .
  ---------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Tnk2.irt.Egf.254.txt

*** Tns3--

rl[551.Tns3.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)                }
  {CLc   | clc     Tns3                                }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Tns3 - Yphos] }
  {CLc   | clc                                         } .
  ------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Tns3.irt.Egf.551.txt

*** Vav1--

rl[388.Vav1.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)                }
  {CLc   | clc   Vav1                                  }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Vav1 - Yphos] }
  {CLc   | clc                                         } .
  --------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Vav1.irt.Egf.388.txt

*** Vav2--

rl[268.Vav2.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Shp2 - Yphos] [Src - act] }
  {CLc   | clc   Vav2                                              }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Shp2 - Yphos] [Src - act]
                 [Vav2 - Yphos]                                    }
  {CLc   | clc                                                     } .
  ----------------------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Vav2.irt.Egf.268.txt

*** Vav3--

rl[374.Vav3.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)                }
  {CLc   | clc   Vav3                                  }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) [Vav3 - Yphos] }
  {CLc   | clc                                         } .
  ------------------------------------------------------
  *** ~/evidence/Egf-Evidence/Vav3.irt.Egf.374.txt

*** Ywhaz--

rl[552.Ywhaz.irt.Egf]:
  {EgfRC | egfrc ([EgfR - Yphos] : Egf)       }
  {CLc   | clc   Ywhaz                        }
  =>
  {EgfRC | egfrc ([EgfR - Yphos] : Egf) Ywhaz }
  {CLc   | clc                                } .
  -----------------------------------------------
  *** ~/evidence/Egf-Evidence/Ywhaz.irt.Egf.552.txt

endm
